Express Pilates Class 4 - Better Exercise Physiology
Our Express Pilates classes are short 10 to 15 minute Pilates workouts designed to get you moving with a focus on improving your core strength and posture. I...
By: Better Exercise Physiology
The rest is here:
Express Pilates Class 4 - Better Exercise Physiology - Video
Lesson 5 - Basic Exercise Physiology
Lesson 5 - Basic Exercise Physiology.
By: Monique Guidry
Continue reading here:
Lesson 5 - Basic Exercise Physiology - Video
NL16 Cell Physiology by Aj.Rungtawan 17-2-14
By: IChiMaii
Go here to read the rest:
NL16 Cell Physiology by Aj.Rungtawan 17-2-14 - Video
Raleigh, NC (PRWEB) February 18, 2014
Applied Research Associates, Inc. (ARA) will present BioGears(TM) at the Medicine Meets Virtual Reality Conference(MMVR) in Manhatttan Beach, California.
BioGears(TM) is a $7M, multi-year program that will deliver an open source, comprehensive, extensible human physiology engine that will drive immersive medical education and training technologies. The BioGears(TM) project will enable the public to develop medical simulations that will benefit military as well as civilian medicine. Dr. Bryan Bergeron, a consulting medical doctor and a researcher working on BioGears(TM), said this project represents the next stage in the evolution of modern physiology computing. It's logical, accessible, extensible, and open. What else could you ask for?
BioGears(TM) physiology modeler, Mr. Rodney Metoyer, will present the four main thrust areas of the program at MMVR. At program maturation, BioGears(TM) will include: 1. An open source physiology engine, 2. An open source common data model, 3. Extensive documentation to enable integration and model extension, and 4. A website that will promote community involvement and contributions.
Mr. Metoyer is a former Army combat medic and understands the importance of advancements in medical training technologies. He said, BioGears(TM) will be a powerful tool because our open source engine and common data model will allow a wide variety of users to create accurate simulated physiology that fits the needs of the medical simulation and training community.
The BioGears(TM) research team is planning the first mini build release of the engine and the full website launch in Fall 2014 with the beta build release in Fall 2015. The mini build will include showcase scenarios that demonstrate the degrees of patient customization, the numerous insults and injuries, and the various assessments available in the engine. The showcase scenarios will serve as a framework to enable community discussions about how to contribute to the project.
One of the showcase scenarios will simulate a healthy adult male who is dehydrated and performing work at high altitudes. This scenario will demonstrate our energy balance system that Mr. Metoyer and Dr. Bergeron are developing jointly. Mr. Metoyer said, The energy system will allow us to model nutrient consumption and heat production, heat flow, the physiological effects of exercise and rest, dehydration, and fed or starved states. It will provide the ability for our simulated humans of various body states to interact with and react to differing environmental conditions.
Rodney Metoyer will present BioGears(TM) for the Military Medical Simulation Session at MMVR on Wednesday, February 19 2014, at 1:20 at the Manhattan Beach Marriott Hotel. This session will inform the public of developments within the military medical simulation community, share ideas and engage the research community in advancing simulation goals.
If you are interested in the BioGears(TM) program and plan to attend MMVR, please stop by our booth or contact Jenn Carter (jcarter(at)ara(dot)com) to set up a meeting with our team.
###
Read more here:
ARA's BioGears(TM) Presented at Medicine Meets Virtual Reality Conference
Physiology Call of Duty
And now for something completely different. ----------------------------------------------------------------------------- Follow Me: http://www.twitter.com/T...
By: christrout91
Original post:
Physiology & Call of Duty - Video
M. Elizabeth Tidball, a physiology professor at George Washington University whose surveys of graduates of womens-only colleges pointed to the advantages of such institutions and had an enduring influence on debates about academic and professional opportunities for women, died Feb. 3 at the Buckinghams Choice retirement community in Adamstown, Md. She was 84.
The cause was pancreatic cancer, said Margaret Shannon, the historian and archivist of the Cathedral Choral Society, the resident symphonic chorus of Washington National Cathedral. Dr. Tidball sang in the choruss alto section for nearly five decades and was the societys president from 1982 to 1984. She was the first woman to hold that post.
(Family photo) - M. Elizabeth Tidball, a physiology professor at George Washington University and a member of the Cathedral Choral Society, presents flowers to Paul Callaway, the groups founder and first musical director, after his final concert in 1984.
A look at those who have died this year.
Known to her acquaintances as Lee, Dr. Tidball joined George Washington University in 1960 and remained a researcher and professor in the physiology department until her retirement in 1994. She was widely known as an advocate for women in academia generally and the sciences in particular.
Her prominence stemmed in large part from a study she began in the late 1960s. Dr. Tidball examined 1,500 listings in the reference guide Whos Who of American Women and found that graduates of womens colleges were two to three times more likely than graduates of coeducational colleges to be included in the guide for their professional accomplishments.
The article appeared in the journal Educational Record in 1973. Critics have noted that the study did not control for socioeconomic background or the self-selecting nature of student body populations. But for years, the article continued to be cited in discussions of womens educational and career paths.
Its publication followed closely the enactment in 1972 of Title IX, the federal legislation prohibiting sex discrimination in education, and coincided with an intensifying debate about the role of womens colleges in American society. The number of such institutions fell, according to the New York Times, from 300 in 1960 to 70 in 2000.
Dr. Tidball a graduate of the womens-only Mount Holyoke College in South Hadley, Mass. steadfastly championed their advantages. Among their merits, she argued, was the greater proportion of female faculty members and administrators who could be role models for female students.
In the 1970s and 80s, she conducted variations on her original study, including surveys of women who received doctoral degrees and who were admitted to medical schools. Those surveys, too, pointed to the merits of womens institutions, said Lisa Wolf-Wendel, a co-author with Dr. Tidball of the volume Taking Women Seriously: Lessons and Legacies for Educating the Majority.
Continued here:
M. Elizabeth Tidball, GWU professor and Cathedral Choral Society president, dies
Everyday our cells take in nutrients from food and convert them into the building blocks that make life possible. However, it has been challenging to pinpoint exactly how a single nutrient or vitamin changes gene expression and physiology. Scientists at the University of Massachusetts Medical School have developed a novel interspecies model system that allows these questions to be answered. In a study appearing in the journal Cell, UMMS researchers use this new approach to show how bacterially supplied vitamin B12 changes gene expression, development and fertility in the model organism C. elegans.
"In mammals, micronutrients are provided by a combination of diet and gut flora," said A.J. Marian Walhout, PhD, co-director of the Program in Systems Biology and professor of molecular medicine at UMMS and senior author of the study. "We've developed a powerful approach that can be used to unravel the complex interaction between nutrients, gene expression and physiology by systematically studying both the predator (worm) and the prey (bacteria). With it we can begin to answer important questions about how what we eat affects how we function."
The key to the study was a set of complimentary genetic screens performed on the transparent roundworm C. elegans and two kinds of bacteria that comprised the worm's diet -- Comamonas and E. coli. In a pair of papers published last year, Walhout and colleagues described dramatic changes in gene expression between worms fed only Comamonas and those fed only E. coli bacteria. Linked to these genetic changes were profound physiological differences between the worms. Comamonas-fed worms developed faster and were less fertile than their E. coli-fed counterparts.
By genetically dissecting the two bacteria and using a special C. elegans strain developed to sense changes to diet-related gene expression, Walhout and colleagues were able to zero in on a set of genes present in Comamonas but absent from E. coli. Further testing confirmed that these genes were responsible for producing vitamin B12 in Comamonas and it was the presence of the micronutrient that accounted for the genetic and physiological differences seen between the worms on different diets.
Importantly, Walhout found that vitamin B12 fulfills two important functions in C. elegans: It helps regulate development through the methionine/SAM cycle, which is needed for the production of cell membranes in new cells. It also alleviates potentially toxic buildups of the short-chain fatty acid propionic acid, which can alter gene expression or harm cells.
"C. elegans fed E. coli are actually vitamin B12 deficient and this reflects only one natural state of the animal," said Walhout. "Because E. coli has been the standard laboratory diet for decades it would be interesting to study other characteristics of the worm, such as behavior, mating and movement, on a vitamin B12 rich diet."
Walhout and colleagues say that this system can also be adapted to identify genetic and physiological changes caused by other micronutrients in C. elegans. With the proper human analogs, it's possible that we could one day predict the precise interaction between diet, gene expression and physiology that occurs when we eat a carrot, hamburger, steak or any other food. Doing so might someday lead to new insights into a variety of conditions or diseases such as high cholesterol, heart disease, diabetes and obesity. It can also be used to explore the precise benefits of bacteria found in gut flora.
"It turns out a single transgenic worm is a powerful tool for exploring the complex interaction between macro and micronutrients, gene expression and physiology," said Emma Watson, a doctoral student in the Walhout Lab and first author on the Cell study.
Story Source:
The above story is based on materials provided by University of Massachusetts Medical School. Note: Materials may be edited for content and length.
Original post:
Vitamin B12 accelerates worm development: New model for isolating the effects of nutrients on gene expression and ...
PUBLIC RELEASE DATE:
13-Feb-2014
Contact: Lisa Larson lisa.larson@umassmed.edu 508-856-2000 University of Massachusetts Medical School
WORCESTER, MA Everyday our cells take in nutrients from food and convert them into the building blocks that make life possible. However, it has been challenging to pinpoint exactly how a single nutrient or vitamin changes gene expression and physiology. Scientists at the University of Massachusetts Medical School have developed a novel interspecies model system that allows these questions to be answered. In a study appearing in the journal Cell, UMMS researchers use this new approach to show how bacterially supplied vitamin B12 changes gene expression, development and fertility in the model organism C. elegans.
"In mammals, micronutrients are provided by a combination of diet and gut flora," said A.J. Marian Walhout, PhD, co-director of the Program in Systems Biology and professor of molecular medicine at UMMS and senior author of the study. "We've developed a powerful approach that can be used to unravel the complex interaction between nutrients, gene expression and physiology by systematically studying both the predator (worm) and the prey (bacteria). With it we can begin to answer important questions about how what we eat affects how we function."
The key to the study was a set of complimentary genetic screens performed on the transparent roundworm C. elegans and two kinds of bacteria that comprised the worm's diet Comamonas and E. coli. In a pair of papers published last year, Walhout and colleagues described dramatic changes in gene expression between worms fed only Comamonas and those fed only E. coli bacteria. Linked to these genetic changes were profound physiological differences between the worms. Comamonas-fed worms developed faster and were less fertile than their E. coli-fed counterparts.
By genetically dissecting the two bacteria and using a special C. elegans strain developed to sense changes to diet-related gene expression, Walhout and colleagues were able to zero in on a set of genes present in Comamonas but absent from E. coli. Further testing confirmed that these genes were responsible for producing vitamin B12 in Comamonas and it was the presence of the micronutrient that accounted for the genetic and physiological differences seen between the worms on different diets.
Importantly, Walhout found that vitamin B12 fulfills two important functions in C. elegans: It helps regulate development through the methionine/SAM cycle, which is needed for the production of cell membranes in new cells. It also alleviates potentially toxic buildups of the short-chain fatty acid propionic acid, which can alter gene expression or harm cells.
"C. elegans fed E. coli are actually vitamin B12 deficient and this reflects only one natural state of the animal," said Walhout. "Because E. coli has been the standard laboratory diet for decades it would be interesting to study other characteristics of the worm, such as behavior, mating and movement, on a vitamin B12 rich diet."
Walhout and colleagues say that this system can also be adapted to identify genetic and physiological changes caused by other micronutrients in C. elegans. With the proper human analogs, it's possible that we could one day predict the precise interaction between diet, gene expression and physiology that occurs when we eat a carrot, hamburger, steak or any other food. Doing so might someday lead to new insights into a variety of conditions or diseases such as high cholesterol, heart disease, diabetes and obesity. It can also be used to explore the precise benefits of bacteria found in gut flora.
See the rest here:
Vitamin B12 accelerates worm development
Image Caption: Analysis for the distribution of shapes of melanin-containing organelles (melanosomes) in fossil and living amniotes shows that fuzz-covered dinosaurs like Sinosauropteryx share similarities with living lizards, turtles and crocodilians. In these living taxa color and the shape of the melanosomes are not linked in such a way that color can be reconstructed from melanosome shape alone. Melanosomes in Sinosauropteryx don't presently tell us if this animal was brown, blackish or grey. However, feathered dinosaurs are similar to birds, and we can estimate their color. Credit: Li et al. (authors)
University of Texas at Austin
New research that revises the rules allowing scientists to decipher color in dinosaurs may also provide a tool for understanding the evolutionary emergence of flight and changes in dinosaur physiology prior to its origin.
In a survey comparing the hair, skin, fuzz and feathers of living terrestrial vertebrates and fossil specimens, a research team from The University of Texas at Austin, the University of Akron, the China University of Geosciences and four other Chinese institutions found evidence for evolutionary shifts in the rules that govern the relationship between color and the shape of pigment-containing organelles known as melanosomes, as reported in the Feb. 13 edition of Nature.
At the same time, the team unexpectedly discovered that ancient maniraptoran dinosaurs, paravians, and living mammals and birds uniquely shared the evolutionary development of diverse melanosome shapes and sizes. (Diversity in the shape and size of melanosomes allows scientists to decipher color.) The evolution of diverse melanosomes in these organisms raises the possibility that melanosome shape and size could yield insights into dinosaur physiology.
Melanosomes have been at the center of recent research that has led scientists to suggest the colors of ancient fossil specimens covered in fuzz or feathers.
Melanosomes contain melanin, the most common light-absorbing pigment found in animals. Examining the shape of melanosomes from fossil specimens, scientists have recently suggested the color of several ancient species, including the fuzzy first-discovered feathered dinosaur Sinosauropteryx, and feathered species like Microraptor and Anchiornis.
According to the new research, color-decoding works well for some species, but the color of others may be trickier than thought to reconstruct.
Comparing melanosomes of 181 extant specimens, 13 fossil specimens and all previously published data on melanosome diversity, the researchers found that living turtles, lizards and crocodiles, which are ectothermic (commonly known as cold-blooded), show much less diversity in the shape of melanosomes than birds and mammals, which are endothermic (warm-blooded, with higher metabolic rates).
The limited diversity in melanosome shape among living ectotherms shows little correlation to color. The same holds true for fossil archosaur specimens with fuzzy coverings scientists have described as protofeathers or pycnofibers. In these specimens, melanosome shape is restricted to spherical forms like those in modern reptiles, throwing doubt on the ability to decipher the color of these specimens from fossil melanosomes.
Read the rest here:
Revision To Rules To Decipher Color In Dinosaurs Suggests Connection Between Color And Physiology
Everyday our cells take in nutrients from food and convert them into the building blocks that make life possible. However, it has been challenging to pinpoint exactly how a single nutrient or vitamin changes gene expression and physiology. Scientists at the University of Massachusetts Medical School have developed a novel interspecies model system that allows these questions to be answered. In a study appearing in the journalCell, UMMS researchers use this new approach to show how bacterially supplied vitamin B12 changes gene expression, development and fertility in the model organismC. elegans.
In mammals, micronutrients are provided by a combination of diet and gut flora, said A.J. Marian Walhout, PhD, co-director of the Program in Systems Biology and professor of molecular medicine at UMMS and senior author of the study. Weve developed a powerful approach that can be used to unravel the complex interaction between nutrients, gene expression and physiology by systematically studying both the predator (worm) and the prey (bacteria). With it we can begin to answer important questions about how what we eat affects how we function.
The key to the study was a set of complimentary genetic screens performed on the transparent roundwormC. elegansand two kinds of bacteria that comprised the worms diet ComamonasandE. coli. In a pair of papers published last year, Walhout and colleagues described dramatic changes in gene expression between worms fed onlyComamonasand those fed onlyE. colibacteria. Linked to these genetic changes were profound physiological differences between the worms.Comamonas-fed worms developed faster and were less fertile than theirE. coli-fed counterparts.
By genetically dissecting the two bacteria and using a specialC. elegansstrain developed to sense changes to diet-related gene expression, Walhout and colleagues were able to zero in on a set of genes present inComamonasbut absent fromE. coli. Further testing confirmed that these genes were responsible for producing vitamin B12 inComamonasand it was the presence of the micronutrient that accounted for the genetic and physiological differences seen between the worms on different diets.
Importantly, Walhout found that vitamin B12 fulfills two important functions inC. elegans: It helps regulate development through the methionine/SAM cycle, which is needed for the production of cell membranes in new cells. It also alleviates potentially toxic buildups of the short-chain fatty acid propionic acid, which can alter gene expression or harm cells.
C. elegansfedE. coliare actually vitamin B12 deficient and this reflects only one natural state of the animal, said Walhout. BecauseE. colihas been the standard laboratory diet for decades it would be interesting to study other characteristics of the worm, such as behavior, mating and movement, on a vitamin B12 rich diet.
Walhout and colleagues say that this system can also be adapted to identify genetic and physiological changes caused by other micronutrients inC. elegans. With the proper human analogs, its possible that we could one day predict the precise interaction between diet, gene expression and physiology that occurs when we eat a carrot, hamburger, steak or any other food. Doing so might someday lead to new insights into a variety of conditions or diseases such as high cholesterol, heart disease, diabetes and obesity. It can also be used to explore the precise benefits of bacteria found in gut flora.
It turns out a single transgenic worm is a powerful tool for exploring the complex interaction between macro and micronutrients, gene expression and physiology, said Emma Watson, a doctoral student in the Walhout Lab and first author on theCellstudy.
Like Loading...
Follow this link:
B12 drives gene expression
FORT LAUDERDALE, Florida, February 14. THE 2014 Legends of Texas Clinic, sponsored by ASCA, will be April 11, 12, 7 13 in Houston, Texas.
Clinic Schedule 8 AM -- 4 PM Level 3 Physiology of Training Course
5 PM -- 6 PM Keynote: The Art of Selling the Sport of Swimming to Parents and Athletes John Leonard, ASCA
6:15 PM -- 7:15 PM What are the Components of the Environment that can Develop Elite Athletes? Panel Discussion
8 AM -- 4 PM Level 3 Physiology of Training Course John Leonard, ASCA
5 PM -- 6 PM Keynote: The Art of Selling the Sport of Swimming to Parents and Athletes John Leonard, ASCA
6:15 PM -- 7:15 PM What are the Components of the Environment that can Develop Elite Athletes? Panel Discussion
8 AM -- 4 PM Level 3 Physiology of Training Course John Leonard, ASCA
5 PM -- 6 PM Keynote: The Art of Selling the Sport of Swimming to Parents and Athletes John Leonard, ASCA
6:15 PM -- 7:15 PM What are the Components of the Environment that can Develop Elite Athletes? Panel Discussion
See more here:
The 2014 Legends of Texas Clinic
Change your physiology
Change your physiology change your emotions.
By: tera littlejohn
See the article here:
Change your physiology - Video
Diffusion Its Importance for Human Physiology : Biology DNA
Subscribe Now: http://www.youtube.com/subscription_center?add_user=ehoweducation Watch More: http://www.youtube.com/ehoweducation Diffusion is passive moveme...
By: eHowEducation
See the original post here:
Diffusion & Its Importance for Human Physiology : Biology & DNA - Video
St Mary #39;s MSc Applied Sport and Exercise Physiology Postgraduate Programme
Hear from St Mary #39;s University students on the MSc Applied Sport and Exercise Physiology postgraduate programme. Part of the School of Sport, Health and Appl...
By: St Mary #39;s University, Twickenham
Go here to read the rest:
St Mary's MSc Applied Sport and Exercise Physiology Postgraduate Programme - Video
Physiology of Memory (Part 6)
The role of PKM zeta, part 1.
By: Brian Kurilla
More here:
Physiology of Memory (Part 6) - Video
Lipids are a diverse collection of macromolecules essential for normal physiology, but the tissue distribution and function for many individual lipid species remain unclear. Here, we report a mass spectrometry survey of lipid abundance across 18 mouse tissues, detecting ~1,000 mass spectrometry features, of which we identify 179 lipids from the glycerolipids, glycerophospholipids, lysophospholipids, acylcarnitines, sphingolipids and cholesteryl ester classes. Our data reveals tissue-specific organization of lipids and can be used to generate testable hypotheses. For example, our data indicates that circulating triglycerides positively and negatively associated with future diabetes in humans are enriched in mouse adipose tissue and liver, respectively, raising hypotheses regarding the tissue origins of these diabetes-associated lipids. We also integrate our tissue lipid data with gene expression profiles to predict a number of substrates of lipid-metabolizing enzymes, highlighting choline phosphotransferases and sterol O-acyltransferases. Finally, we identify several tissue-specific lipids not present in plasma under normal conditions that may be of interest as biomarkers of tissue injury, and show that two of these lipids are released into blood following ischemic brain injury in mice. This resource complements existing compendia of tissue gene expression and may be useful for integrative physiology and lipid biology.
Original post:
A systematic survey of lipids across mouse tissues ...
Contact Information
Available for logged-in reporters only
Newswise BIRMINGHAM, Ala. The idea that sex sells is generally accepted as fact. The idea that the sex of cells is important to biomedical research is not as well-known, but an article co-written by a researcher at the University of Alabama at Birmingham, suggests that the sex of individual cells matters.
The sex of a cell is determined by the presence of sex chromosomes: every cell can be categorized as either male or female. The significance of a cells sex is a concept that has been generally overlooked by the research community, but there is now a growing body of evidence that has some researchers examining important implications.
Male cells have an X and a Y chromosome, while female cells have two X chromosomes, said Cathy Fuller, Ph.D., associate professor in the Department of Cell, Developmental and Integrative Biology at UAB. There is now good reason to consider that studies conducted in male cells will produce results different from those of identical studies using female cell lines. This could have a profound effect on fields such as personalized medicine.
This month, Fuller, along with colleague Paul Insel, Ph.D., of the departments of Pharmacology and Medicine at the University of California-San Diego, published an editorial in the American Journal of Physiology-Cell Physiology called I Dont Know the Question, but Sex is Definitely the Answer! The editorial comes on the heels of a 2012 decision by the American Physiology Society to require authors to report the sex of the cells lines, biological materials and animals used in their experiments.
Fuller and Insel looked at two articles published in AJP-Cell and one in Nature that laid out the reasons that the APS decision to disclose the sex of cell lines was essential. They wrote that the lessons learned from these articles suggest the APS policy could have an important effect on patient care.
We have assumed that cells bearing an XY genotype behave the same as cells that are XX, but we dont really know if that is correct, said Fuller. Do T-84 cells, derived from a male colon cancer patient, behave the same as Ht-29 colon cancer cells, derived from a female? And will a colon cancer drug tested in one cell line work in the same fashion in all patients?
An additional complication, according to Fuller, is that many cell lines frequently used in research are old some have been around for more than 50 years and some supposedly male lines have lost the Y chromosome through the many repetitive cell culture cycles.
As we move closer to the concept of personalized medicine, where drugs and therapies can be tailored for the individual patient, we will need a more complete understanding of the physiology of that patient down to the cellular level, Fuller said. A drug that was tested in a cell line without a Y chromosome might not work as well in a patient who does have Y chromosomes. This could help explain why certain drugs work better in some patients than in others. Fuller says investigators working on developing drugs such as small molecules and biologics will need to consider that sex differences may underlie differences in responsiveness of different cells used in high-throughput screens, as well as considering the sex of the patient group to whom the drugs are targeted. Sex differences will be particularly important in stem cell-based therapies, such that the sex of both the donor and the recipient should be considered. She also suspects that other scientific journals will follow suit and require investigators to identify the sex of their cell lines. The good news is that the sex of many of the major cell lines currently in use is known and that information is available to researchers. About UAB Known for its innovative and interdisciplinary approach to education at both the graduate and undergraduate levels, the University of Alabama at Birmingham is an internationally renowned research university and academic medical center and the state of Alabamas largest employer, with some 23,000 employees and an economic impact exceeding $5 billion annually on the state. The five pillars of UABs mission deliver knowledge that will change your world: the education of students, who are exposed to multidisciplinary learning and a new world of diversity; research, the creation of new knowledge; patient care, the outcome of bench-to-bedside translational knowledge; service to the community at home and around the globe, from free clinics in local neighborhoods to the transformational experience of the arts; and the economic development of Birmingham and Alabama. Learn more at http://www.uab.edu.
Read more:
Sex Cells
artery review for anatomy and physiology 2 elnmeer
vessels review for test.
By: ketrava
Read the original:
artery review for anatomy and physiology 2 elnmeer - Video