Marco Luigetti,1,2 Angela Romano,2 Andrea Di Paolantonio,2 Giulia Bisogni,3 Mario Sabatelli2,3

1Neurology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; 2Universit Cattolica del Sacro Cuore, Rome, Italy; 3Centro Clinico NEMO Adulti, Rome, Italy

Correspondence: Marco LuigettiNeurology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo A Gemelli 8, Rome 00168, ItalyTel +39-06-3015 4435Fax +39-06-3550 1909Email mluigetti@gmail.com

Abstract: Hereditary transthyretin amyloidosis (hATTR) with polyneuropathy (formerly known as Familial Amyloid Polyneuropathy) is a rare disease due to mutations in the gene encoding transthyretin (TTR) and characterized by multisystem extracellular deposition of amyloid, leading to dysfunction of different organs and tissues. hATTR amyloidosis represents a diagnostic challenge for neurologists considering the great variability in clinical presentation and multiorgan involvement. Generally, patients present with polyneuropathy, but clinicians should consider the frequent cardiac, ocular and renal impairment. Especially a hypertrophic cardiomyopathy, even if usually latent, is identifiable in at least 50% of the patients. Therapeutically, current available options act at different stages of TTR production, including synthesis inhibition (liver transplantation and/or gene-silencing drugs) or tetramer TTR stabilization (TTR stabilizers), increasing survival at different disease stages.

Keywords: amyloid, polyneuropathy, clinical care, therapy, transthyretin

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Diagnosis and Treatment of Hereditary Transthyretin Amyloidosis (hATTR | TCRM - Dove Medical Press

WESTERLY "Time is brain" is a phrase used by doctors to stress the importance of rapid care for stroke patients.

"If someone waits too long, unfortunately, there may be less that we can do to help them," Dr. Ryan Carter, who chairs the Westerly Hospital Emergency Department, said during a recent interview.

With the importance of a speedy response in mind, Westerly Hospital, after completing a long certification process, is once again able to accept and provide initial treatment to all but the most severe stroke patients. The service went into effect on Jan. 1.

For about the previous 10 years, Rhode Island Department of Health regulations required stroke patients to be treated at either primary or comprehensive stroke centers. But now a third category acute stroke ready has been established. Westerly Hospital gained the certification as an acute stroke ready facility from the Joint Commission on Accreditation of Healthcare Organizations last February, and the state's emergency medical services protocols were updated more recently to reflect the new certification category.

The certification allows smaller and rural hospitals to demonstrate their ability to comply with standards of care for the initial treatment of stroke patients when prompt action and proper medications can save lives and limit the long-term disabling effects of strokes.

As an acute stroke ready facility, Westerly Hospital has shown it has the infrastructure and capability to care for acute strokes, including administration of intravenous thrombolytic therapy. Most acute stroke patients will be transferred to a primary or comprehensive stroke center that would provide ongoing care and / or endovascular procedures after initial stabilization in Westerly.

To gain the acute stroke ready certification, the hospital had to demonstrate four basic capabilities: access to trained medical personnel who are able to assess stroke patients; access to a neurologist; quick access to a CAT scan; and a system in place to deliver the clot busting intravenous thrombolytic therapy.

"Because time is brain we need to get this medication to these patients as quick as possible," said Lisa Bedard, stroke and neurodiagnostics manager at Westerly Hospital.

The lack of in-house neurologists had previously been an obstacle for Westerly Hospital, but the evolution of telemedicine and the hospital's acquisition by Yale New Haven Health in 2016 allow Yale New Haven neurologists who specialize in stroke care to assess patients remotely through the use of a telecart. The device includes an audio component and a high definition camera that enable neurologists in New Haven to see and hear patients as if they were in the same room. "The doctor can see anything that I can see," said Marlea Bergeson, a registered nurse and clinical coordinator of the Westerly Hospital Emergency Department.

When assessing whether a patient has suffered a stroke, doctors look for both overt and subtle signs such as facial droop, facial asymmetry, whether a patient's pupils are equal, and quality of speech. Neurologists in New Haven are notified as soon as Westerly Hospital receives a potential stroke patient and can see CAT scan results immediately in real time before patients even leave the scan room.

In addition to being certified as an acute stroke ready facility, the hospital worked with the Rhode Island Department of Health's Ambulance Advisory Board to get protocols changed to allow for the acceptance and treatment of stroke patients.

"That was a big hurdle to get over because we had to convince them so everyone knows what acute stroke ready hospitals are," said Tim Law, chief paramedic for Westerly and L+M hospitals and a member of the Rhode Island Stroke Task Force.

With the new protocols in place, patients who suffer strokes in the Westerly region now stand a greater chance of receiving care quickly. Rather than a 20 minute ride to New London or a slightly longer trip to Wakefield, they can be treated at Westerly Hospital.

"The advantage to that is time. Somebody in Westerly will get here and get imaged and treated more quickly than being transported to L+M or South County Hospital and that is advantageous from a health point of view," said Dr. William Conlin, an emergency medicine physician at Westerly Hospital.

Because each passing minute is critical, when paramedics respond to a 911 call they score a patient's symptoms to determine the type of facility a patient should go to. More severe symptoms require treatment at a primary or comprehensive stroke center.

Ralph Miro, director of nursing for the Westerly Hospital Emergency Department, stressed the importance of public awareness of stroke symptoms. He recommended using acronym FAST: face drooping, arm weakness, speech difficulty, and time to call 911.

"The tendency for many families is to put the patient in the car and bring them in that manner, but actually what they should do is access 911 and ensure that they have highly trained medical personnel to bring them in as soon as possible," Miro said.

Strokes occur when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts.When that happens, part of the brain cannot get the blood and oxygen it needs.

Bedard thanked state Sen. Dennis Algiere, R-Westerly, for his help in developing new legislation that allows for the recognition of acute stroke ready hospitals in Rhode Island.

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Acute stroke response is again close at hand in Westerly area - The Westerly Sun

In 2019, the market size of Rare Neurological Disease Treatment Market is million US$ and it will reach million US$ in 2025, growing at a CAGR of from 2019; while in China, the market size is valued at xx million US$ and will increase to xx million US$ in 2025, with a CAGR of xx% during forecast period.

In this report, 2019 has been considered as the base year and 2019 to 2025 as the forecast period to estimate the market size for Rare Neurological Disease Treatment .

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Market Potential

Genetically engineered to model a predominantly, an inherited, and a rare neurological human disease called ataxia telangiectasia (AT), the ExeGen ATM MiniSwine has been cleared for commercial use by the FDA. In regard to the model, the FDA has exercised enforcement discretion. This powerful investigational platform by Exemplar could be offered to drug developers, researchers, and scientists looking to develop innovative therapeutics and define disease mechanisms to address ATs pathologies. It is expected to enable improved predictive efficacy and superior translational research.

Global Rare Neurological Disease Treatment Market: Regional Outlook

North America is envisaged to rake in a handsome demand for rare neurological disease treatment because such diseases are considered to be a serious health concern. However, some researchers say there are only a few people affected by rare neurological conditions. The demand for rare neurological disease treatment could be high due to lack of sufficient options and complications of the disease. Moreover, healthcare and government institutions in the region are collaborating to develop a strong research network for the purpose of allowing advancement in rare disease treatment, enrollment in studies and trials, and data sharing.

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Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2014 to 2019.

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Chapter 13, 14 and 15, to describe Rare Neurological Disease Treatment sales channel, distributors, customers, research findings and conclusion, appendix and data source.

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Rare Neurological Disease Treatment Market To Exceed Revenues Worth US$ By The End Of 2017 2025 Dagoretti News - Dagoretti News

The Neurology Software market has been changing all over the world and we have been seeing a great growth In the Neurology Software market and this growth is expected to be huge by 2025. The growth of the market is driven by key factors such as manufacturing activity, risks of the market, acquisitions, new trends, assessment of the new technologies and their implementation. This report covers all of the aspects required to gain a complete understanding of the pre-market conditions, current conditions as well as a well-measured forecast.

The report has been segmented as per the examined essential aspects such as sales, revenue, market size, and other aspects involved to post good growth numbers in the market.

Top Companies are covering This Report:- Epic, Brainlab, healthfusion, Athenahealth, Practice Fusion, Nextgen, Bizmatics, Greenway Health, Allscripts, Kareo, Advanced Data Systems, NueMD, etc.

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Description:

In this report, we are providing our readers with the most updated data on the Neurology Software market and as the international markets have been changing very rapidly over the past few years the markets have gotten tougher to get a grasp of and hence our analysts have prepared a detailed report while taking in consideration the history of the market and a very detailed forecast along with the market issues and their solution.

The given report has focused on the key aspects of the markets to ensure maximum benefit and growth potential for our readers and our extensive analysis of the market will help them achieve this much more efficiently. The report has been prepared by using primary as well as secondary analysis in accordance with porters five force analysis which has been a game-changer for many in the Neurology Software market. The research sources and tools that we use are highly reliable and trustworthy. The report offers effective guidelines and recommendations for players to secure a position of strength in the Neurology Software market. The newly arrived players in the market can up their growth potential by a great amount and also the current dominators of the market can keep up their dominance for a longer time by the use of our report.

Neurology Software Market Type Coverage:

Advanced Neurology EMR Software, Other, etc.

Neurology Software Market Application Coverage:

Hospitals, College & Research Institutes, Other, etc.

Market Segment by Regions, regional analysis covers

North America (United States, Canada, Mexico)

Asia-Pacific (China, Japan, Korea, India, Southeast Asia)

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Competition analysis

As the markets have been advancing the competition has increased by manifold and this has completely changed the way the competition is perceived and dealt with and in our report, we have discussed the complete analysis of the competition and how the big players in the Neurology Software market have been adapting to new techniques and what are the problems that they are facing.

Our report which includes the detailed description of mergers and acquisitions will help you to get a complete idea of the market competition and also give you extensive knowledge on how to excel ahead and grow in the market.

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Reports Intellect is your one-stop solution for everything related to market research and market intelligence. We understand the importance of market intelligence and its need in todays competitive world.

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Neurology Software Market to Witness Rapid Growth by 2025 | Brainlab, healthfusion, Athenahealth, Practice Fusion, Nextgen, Bizmatics. Dagoretti News...

Jon Becker, For the Daily News

Photo: Michael David-Lorne Jordan/David-Lorne Photographic

Auburn is home to new neurology office

Auburn is now the site of a new neurology office led by the former chairman of neurosciences at MidMichigan Regional Medical Center-Midland.

Dr. Gregory Dardas, now with Owosso-based Memorial HealthCare, is leading the Auburn practice that was unveiled to the public during a recent ribbon-cutting ceremony.

The Memorial Healthcare Institute for Neurosciences and Multiple Sclerosis, located at 4600 Garfield Road, is up and running in a building that formerly housed a temporary employment service agency and civil engineering firm.

"They completely renovated the entire building and have converted it into state-of-the art medical offices," said Paul Wasek, Williams Township supervisor. "Any kind of specialty field that the medical community brings to this area is a welcome sight. It's a good sign that a need is being met."

The Auburn location currently has five employees, including the addition of a new EMG certified technician, who is expected to join the medical team after the first of the year.

"Opening an office for our neurological practice in the Auburn area gives Memorial Healthcare the opportunity to expand our geographical footprint in a way that makes our world-class treatment of complex neurological disorders more accessible to patients across Mid-Michigan," said Brian Long, president & CEO of Memorial Healthcare. "This office will compliment Memorial Healthcare's existing neurological services in the Owosso, Saginaw, Bay City and Midland areas."

Dardas, said officials, is well-suited to lead this specialty practice that will treat a wide variety of neurological conditions.

"Dr. Dardas brings a wealth of knowledge and experience in treating Parkinson's disease, dementia, headaches, peripheral neuropaths, myopathies and neuromuscular diseases to Memorial Healthcare," said Dr. Rany Aburashad, chief of neurology and director of multiple sclerosis at Memorial Healthcare. "This experience will further elevate our ability to provide cutting-edge, industry-leading neurological treatment to our patients."

While Dardas heads up the Auburn practice, he is supported by Memorial's broader team that includes Aburashed, who is credited for being the first in the United States to utilize neurofilament light chain technology testing for MS patients in a clinical setting.

"Patients from all over the world seek out treatment and care for neurological conditions, and we continue to attract the top doctors in other specialty areas whose vision for patient care aligns with ours," said Long. "When patients want the best care, regardless of ailment, they come to Memorial Healthcare."

The new Auburn practice in Williams Township represents another move by Memorial to expand its presence in small communities throughout Mid-Michigan.

"At Memorial Healthcare, our core mission is to provide world class medical treatment combined with small town values," Long said, noting its flagship facility in Owosso is developing a new $30 million Community Wellness Center and also is opening a new location in St. John's. "It's this patient-centric vision that is driving our ambitious growth and development plans."

"Having these types of top-notch medical services available right here in our community is huge," Wasek said. "Our community is aging. People are living longer."

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Auburn is home to new neurology office - Midland Daily News

Novela Neurotech, a company developing AI-powered wireless, smart neural interface systems, joins Canadas Creative Destruction Lab to adjust its health technologies to the needs of patients with difficult neurological disorders.

Our core mission is to foster a new era of neurological treatments by focusing on their electrical signalling within the brain. Rather than flooding the brain with chemical drugs, we aim to precisely interfere with aberrant neural signalling that leads to disorders.

To that end, we are developing a platform that accelerates these technologies at multiple stages, including pre-clinical discovery, clinical trials and post-market, real-world evidence data collection, says Ray Iskander, Cofounder and CEO of Novela Neurotech.

Depression, addiction, epilepsy and chronic pain plague millions of people globally, yet traditional pharmaceutical solutions fail in approximately 30 percent of cases. The root causes of these mental disorders are buried within the electrical communications of complex brain circuits.

By listening in on these brain communications and decoding their messages using neural interfaces, it may be feasible to target and disrupt the brains signals that lead to unsafe neurological episodes, such as seizures or cravings, with a burst of electrical stimulation.

Electrical stimulators, such as spinal cord stimulators for back pain, have been around for decades, but theyre not very adaptable and can only stimulate in a few forms.

We are bringing the power of AI to neural stimulators, miniaturising them into seamless interfaces with the brain, says Dr. Salam Gabran, Technical Cofounder of Novela Neurotech.

The complexity of the brain makes it extremely difficult to record from and decode messages in specific neural circuits. For the past decade, Novela Neurotech has been working on a wireless, bi-directional and flexible interface that is designed to sit within the brain and silently monitor for disease-causing electrical signals.

On 11 December, 2019 Novela Neurotech showcased its production-ready neural interface that miniaturises a roomful of equipment into a device smaller than the tip of a finger at Creative Destruction Lab, a seed-stage program that supports massively-scalable companies rooted in translational science and technology.

The device, made through state-of-the-art microfabrication technologies, is just one aspect of Novelas Neureka platform to accelerate next-generation neurological treatments throughout the entire therapeutic developmental process. During preclinical discovery stage, the software ecosystem promotes data sharing and collaboration between neuroscientists, data scientists and neurologists. Due to the brains complexity and the difficulties for a single institution to gather enough data for mining, a collaborative platform is tantamount for accelerating this initial discovery phase while dramatically reducing research costs.

Depression, addiction, and chronic pain remains some of todays hardest disorders to manage and treat. Its clear that neurological treatments require new therapeutic avenues in addition to pharmaceuticals.

Were thankful for being selected for the Creative Destruction Lab and collaborating with their strong network of accomplished mentors and investors to further bring our technologies, inventions and insights to help millions in need, says Iskander.

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Creating the technology to disrupt seizures and addiction - SciTech Europa

The Interventional Neurology Device market study offers an extensive analysis of the trends observed in the growth against the global setting. This report delivers conclusive information relating to various aspects of the market viz. the commercial applications, size of the industry and speculated profit margin over the planned timeline. It also demonstrates the competitive landscape with an emphasis on the leading producers in the forecast years, highlighting their product portfolios and regional business ventures.

Global Interventional Neurology Device Market Report 2019 Market Size, Share, Price, Trend and Forecast is a professional and in-depth study on the current state of the global Interventional Neurology Device industry.

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The global market size of Interventional Neurology Device is $XX million in 2018 with XX CAGR from 2014 to 2018, and it is expected to reach $XX million by the end of 2026 with a CAGR of XX% from 2019 to 2026.

This report on the Interventional Neurology Device market delivers a cumulative synopsis of the speculations of this business, overall, along with an evaluation of its segmentations. It predicts the Interventional Neurology Device market to advance as one of the most profitable verticals, generating massive revenue by the end of the forecast years, exhibiting a sizable growth rate over the calculated period. The opportunities for growth and expansion that are prominent in the sector as well as the geographical coverage of the industry have also been investigated by the report.

A synopsis of the fundamentals of this report:

Identifying the basic business drivers, challenges, and tactics adopted:

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Outlining the competitive landscape of the Interventional Neurology Device market:

A brief outlook of the key companies in the Interventional Neurology Device market, focusing on companies such as

MedtronicJohnson and JohnsonTerumo CorporationPenumbra, Inc.Merit Medical Systems, IncW.L. Gore & AssociatesMicroport Scientific CorporationMedikit Co., Ltd.StrykerOthers

These particulars additionally consist of a basic summary of the corporations, company profile, and the product portfolio of the company in focus.

The report analyses the gathered information relating to the profits accrued, sales, gross margins, price patterns, revenue and updates on the activities of the company.

Most important types of Interventional Neurology Device products covered in this report are:

Embolization & coilingNeurothrombectomy Devices

Most widely used downstream fields of Interventional Neurology Device market covered in this report are:

Treatment of Cerebral AneurysmsTreatment of Cerebral VasospasmVertebroplasty

Browse complete Interventional Neurology Device report description And Full TOC @ https://www.marketexpertz.com/industry-overview/global-interventional-neurology-device-market

In this study, the years considered to estimate the market size of Interventional Neurology Device are as follows:

History Year: 2014-2018

Base Year: 2018

Estimated Year: 2019

Forecast Year 2019 to 2026

For the data information by region, company, type and application, 2018 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.

Key Stakeholders:

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Interventional Neurology Device Market (2019-2026) | Size, Growth Trends, Future Prospects, And Their Contribution to the Global Industry Scenario |...

A Terrace man is recovering from chemical burns on his face after being attacked with suspected battery acid and police say that the two culprits remain at large.

Mike Anderson, 51, was walking home after attending the Philanthropy Day event at the Terrace Art Gallery on Sparks Street near Davis Avenue at 8 p.m. on Nov. 15 when he was approached by two men, according to RCMP.

One of them asked Anderson, who is legally blind, for the time. But when Anderson brought his wristwatch up close to his face, the two men sprayed him directly in the face with an acidic substance, which he says he believes might be car battery acid.

I felt my face get wet, and thenI thought they were going to hit me, so I covered myself up. But my eyes were burning, an emotional Anderson told the Terrace Standard on Monday.

Unable to see as the chemical singed his eyes and blistered his face, all he could hear was the uproarious laughter from his attackers. Then he heard a womens voice, asking them to leave.

Soon after, they were gone.

READ MORE: Terrace man recovering from machete attack

I could open one of my eyes, it would sting and kept closing, but I found a puddle so I could wash my face. I tried to use my phone but it was slippery, and it wouldnt unlock, Anderson says. But I was close to home.

In a news release after the incident, RCMP described the two suspects as Indigenous and in their 20s. One had a small beard, the other was wearing a hoodie.

For Anderson, who was diagnosed this year with a complex neurological condition, walking the two blocks from the art gallery to his home is more difficult than for most people.

In August, Anderson suffered two herniated discs in his spine and was flown to Vancouver General Hospital for two weeks for doctors to administer a nerve block, a method of producing anesthesia.

Then a month later in September, he was walking over to a follow-up appointment for his back, he started to feel unwell. Fearing something was wrong, Anderson went to the hospital, where he lost feeling on his left side. He was sent back to VGH right away.

Doctors diagnosed Anderson with conversion disorder, a neurological condition that mimics the symptoms of a stroke. Rather than damage the actual structure of the brain, the disorder impacts a persons ability to do certain things, resulting in conditions including blindness, paralysis and speech problems.

They didnt know why it was happening, he says. Then they eliminated stroke and said it was neurological, but no clots, bleeding or tumours, so thats good news but it will still take time to retrain my brain.

After the attack, the only way Anderson was able to tell how close he was from home was because he could smell the gas coming from a sewer lift station, a concrete sewer basin in the ground, and knew his street was the next one over.

He was able to get home, struggled with the security keypad on his front door, and washed his face in the sink. He called his son on his landline, who then came home and took him to the hospital. Hospital staff could still smell the chemical on his clothes when he was admitted, he says.

It smelled like sulfur, like rotten eggs. RCMP arent sure what it was, but hospital staff think it was maybe car battery acid.

It took six hours to completely flush the substance out of his eyes and lungs, he says. Hospital staff treated the painful blisters on Andersons face with a cream.

Although hes trying to recover, the fear of being attacked while walking around Terrace has stayed with him.

I was scared. I didnt know where they were, and my eyes are bad because of other conditions. I just hoped I hoped I could see again, he says.

Anderson has been to a few eye appointments since the attack, and was told while his eyes are still irritated, no permanent damage was done to his already limited vision.

READ MORE: Terrace ranks in top 10 of magazines Canadas Most Dangerous Places list

After being diagnosed, Andersons family started a GoFundMe page and have since started it back up again after he was attacked. So far, theyve raised $7,010 out of their $8,000 goal to pay for Andersons medical expenses.

The community support to help him and his family has been overwhelming, Anderson says.

Karleen Lemiski contacted the Helping Hands of Terrace about Andersons story, and the organization jumped on board to cover any of his prescription costs, along with a monetary donation. The Terrace Royal Canadian Legion Branch 13 also contacted Anderson to see if they could help with any mobility items, such as a wheelchair, a walker, which can be used to help a person with mobility issues get around, and grab-bars.

The Kimmunity Angels Society was also contacted, and they are looking into whether they can reimburse Andersons September medical flight back from VGH, his new glasses or other medical expenses.

MaXXed Out Cross Trainings Denise Manion has also set up a fundraiser for a heavyweight sled pull competition scheduled for Nov. 28 to Dec. 6 to help the Anderson family.

Police are asking anyone who may have seen anything or know anything about this incident to contact investigators at 250-638-7429.

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Terrace man with neurological medical conditions burned in acid attack - Coast Mountain News

Accurate treatment begins with strong diagnostic tools. Theneurologists in Phoenix at Foothills Neurology has both the diagnostics and the specialized treatment necessary to provideexcellent neurology care.

The Foothills Neurology staff consists of a full range of dedicated providers ready to assist your neurological care. Our topneurologist and neurology care providers work as a team to offer patients some of the most comprehensive carein the Phoenix area. As experts in neurological disorders, we treat each individual with compassion and excellent care we would offer our own family. We take time to get to know you as a person, not just a diagnosis. We understandthe anxiety of having a neurological condition can, at times,feel worsethan the condition itself. That is why our dedicated team is here to support you. We take as much time as you need to discuss your condition as well as understand the possibilities and the treatment plan. We are happy to answer your questions and ease your fears by replacing them with genuine support and understanding. Our commitment is to enhance your quality of life. Our patients are in good hands with our strong team of specialists, neurologists and other providers devoted to your health. Schedule an appointment with a Phoenix neurologistat our conveniently located office off theI-10 Maricopa Freeway and East Chandler Boulevard.

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Home | Foothills Neurology

In spite of how they appear, the left and right hemispheres of the human brain tend to be far from perfect reflections of each other. Some neurological disorders can affect that imbalance, causing the two halves to appear strikingly alike.

So far, studies on whether autism is among those conditions have been less than convincing. To get a more definitive answer, researchers analysed thousands of brains and showed there is slightly more symmetry for those on the spectrum.

But what does that really mean?

To get this answer, scientistsfrom the Enhancing Neuro-Imaging Genetics through Meta-Analysis consortium collected decades of brain scans from more than 1,700 individuals diagnosed with autism spectrum disorder (ASD) and more than 1,800 with no diagnosis.

The consortium were hardly strangers to analysing huge banks of data, having only recently conducted a similar study on ASD brain anatomy involving more than 3,000 subjects.

The condition covers a spectrum of characteristics that can make life a little more challenging for some, affecting their ability to socialise, communicate, and process stimuli.

With such variation in behaviours, sensations, and impact, tracing the traits making up ASD down to simple neurological differences is no easy task.

Doing so could help make the disorder easier to diagnose and lead to novel therapies, opening the way to providing better methods of assistance for those who need it.

So researchers have been busy looking for clues on all levels of anatomy, from the genes to the gross architecture of our squishy bits.

There have been plenty of investigations into the overall structures of autism-related brains, discovering subtle differences such as the thickness of the cerebral cortex and how key areas link together.

Comparing the ways our brain's mirrored hemispheres reflect each other is a fair way to understand how they develop and communicate.

After all, for most of us, it's differences both between and within the two halves that governs everything from movement to cognitive processes.

Unfortunately, there's still so much we don't know about this contrast between the hemispheres, or 'lateralisation'. So when it comes to learning how lateralisation might be linked with more profound neurological differences, we're still in the dark ages.

There are studies that have found people with ASD have unusually symmetrical brains. There are also studies that found no such thing.

They also tend to be more left handed, and seem less symmetrical in other areas of the brain.

If you're confused about what to make of the mess of conflicting studies, you're not the only one.

"Previous studies have suggested that people with autism spectrum disorder are less likely to have the typical asymmetries for language dominance or hand preference," says geneticist Merel Postema from the Max Planck Institute for Psycholinguistics in the Netherlands.

"However, it has not been clear whether asymmetry of the brain's anatomy is affected in autism, because different studies have reported different findings."

Comparing the thickness of the cortex forming key parts of the brain's outer layer, the researchers found there was comparably less variability across the hemispheres in brains from people with ASD.

These differences didn't vary much depending on sex, medication, or IQ, making it more likely that there was something about autistic brains that accounted for this increased symmetry.

In spite of the significance of the results, it's not enough of a difference to base a diagnosis on.

"The very small average differences in brain asymmetry between affected people and controls mean that changes of brain asymmetry will not be useful in terms of clinical prediction", says the study's leader, Clyde Francks from the Max Planck Institute for Psycholinguistics.

"But the findings might inform our understanding of the neurobiology of autism spectrum disorder".

Some of the differences, for example, appeared in areas containing networks that work harder while we're resting. Just how this might account for some of autism's traits if at all is a task for future studies.

No doubt, there'll be more research on this in the future. Having more information on how our brain works as a whole not only helps us better understand how ASD arises, but how behaviours and functions common to all of us might develop.

This research was published in Nature Communications.

Go here to see the original:
People With Autism Have More Symmetrical Brains. Here's What That Could Mean - ScienceAlert

Get my MCI Treatment Checklist here: https://gocogno.com/mild-cognitive-impairment-treatment/

The Mayo Clinic guidelines on how to get ready to see a primary care doctor or MCI specialist are here: https://www.mayoclinic.org/diseases-conditions/mild-cognitive-impairment/diagnosis-treatment/drc-20354583

Read the Virginia Laken guest blog on why its important to bring someone with you to every appointment: http://virginialaken.com/2019/10/an-absurd-question-written-by-beth/

I know this seems silly now, in the world of instant, on-demand everything, but when I was a kid, they would show The Wizard of Oz on TV once a year.

For us kids, that was a huge deal. We looked forward to it for weeks. And if you missed it, Oh man, you had to wait a whole year for it to come back on TV again.

So really, all Im saying here is that year is a long time to wait for anything, whether its Dorothy and the witch, or whether its something really significant, like say, your next appointment with your neurologist.

For someone with MCI, you can wait months for that first visit with a neurologist. And then have to wait a year to see the neurologist again.

So you really want to be ready for that visit, to get the most out of it. And thats what I want to talk about today.

Hi, Im Tony Dearing, of GoCogno.com, the website for people with mild cognitive impairment.

If you have MCI, or youre dealing with it in your family, I dont have to tell you how important that first or next visit with the neurologist is. People spend months anxiously awaiting it and stressing out about it.

And I want to make sure that you get the most out of it.

So today, I want to share with you three resources to help you do that.

No. 1 is this excellent resource from the Mayo Clinic. It has put together this helpful resource guide that shows you want to expect from a visit to a neurologist and how to get ready for it. You can see some of the examples here.

If you dont already have this tip sheet, you should get it, and familiarize yourself with it. And heres a link to it:https://www.mayoclinic.org/diseases-conditions/mild-cognitive-impairment/diagnosis-treatment/drc-20354583

Tip No. 2 Familiarize yourself with the treatment guidelines for MCI and be prepared to discuss them with your neurologist.

Almost undoubtedly, your neurologist belongs to the American Academy of Neurology. And the academy has an official set of treatment guidelines for mild cognitive impairment.

There was a period of time, way too long, in fact, when these guidelines had become dated. The academy went more than 15 years without updating these guidelines.

Fortunately, thats now been rectified. The academy has actually updated the guidelines twice in the last three years.

So the current guidelines are complete and up to date, and reflect the very best, latest thinking in how MCI should be treated.

I know you want the best possible treatment, and I want to make sure you get it.

So I put together an MCI Treatment Checklist, which you can sign up for and receive. With it, youll also get my weekly brain health email, if youre not already getting it. Both are absolutely free, and here a link to get the checklist:https://gocogno.com/mild-cognitive-impairment-treatment/

Finally, heres tip No. 3. As youre preparing for that visit, make sure that you have someone, ideally a spouse or family member, whos available to go along with you.

This is really important, and to understand why, I encourage you to read a recent post on the blog Virginia Laken, who has MCI and writes about her experiences. This recent piece is a guest post written by Virginias daughter, describing a visit that her mother had with the neurologist and why it was so important that the daughter was there too. You can read that guest post here:http://virginialaken.com/2019/10/an-absurd-question-written-by-beth/

So thats three resources to help you prepare for your next visit to the neurologist. How about you? Do you have any suggestions or tips? Add them to the comments below, or send me an email at tonydearing@gocogno.com.

I hope to hear from you, and I look forward to seeing you again next week. Until then, as always, be kind to your mind.

See the rest here:
How to get ready for that all-important visit to a neurologist - GoCogno.com

Shore Neurology was honored to have Dr. Ferencz listed as a Top Doctor in Toms River in 2016.

Shore Neurology, P.A. opened in 1986 with the goal of providing progressive neurological care to the Ocean and Monmouth County communitities. Our seven physicians and our nurse practitioner deliver care in our offices in Toms River and Brick, New Jersey.

Our providers are specialists in the treatment of disorders of the nervous system and address diseases of the brain, spinal cord, nerves and muscles. Some of the problems that our neurologists will diagnose and treat are strokes, epilepsy (seizures), headaches and migraines, dementias (Alzheimers disease), multiple sclerosis, Parkinsons disease and various forms of pain. Our neurologists may serve as consultants to other physicians as well as provide long-term care to patients with chronic neurological disorders.

We are a general neurology group practice offering extensive care for a wide range of neurological conditions. We offer several types of neurological subspecialty expertise, including:

Electroencephalograms, electromyograms, nerve conduction velocity studies, physical therapy, carotid ultrasound, and transcranial doppler are all performed in our office.

Our hospital affiliations include Community Medical Center, Ocean Medical Center, HealthSouth Rehabilitation Center and Shore Rehabilitation Institute.

Our physicians and nurse practitioners endeavor to provide you with the best comprehensive neurologic care available.

We hope you find this website helpful in your health and medical care decisions. Please contact us with any questions or for an appointment.

More:
Shore Neurology, P.A. | Jersey Shore, NJ, Neurologists

Expertise and Innovative Care for Neurological Disorders

Headaches, stroke, pain and other conditions related to the nervous system can sometimes evade precise diagnosis and treatment. University Hospitals Neurological Instituteat UH Ahuja Medical Centers Risman Pavilion provides immediate access to an unprecedented level of neurological care for patients in Clevelands eastern suburbs. From standard diagnostic evaluations to advanced neurosurgical procedures, we offer a full range of neurological services and a sophisticated level of care that cannot be found anywhere else on the eastside.

More than just neurology and neurosurgery, our integrated multidisciplinary clinic is staffed by our senior faculty, many of whom are nationally recognized experts in a wide variety of disciplines.

In addition to general neurology, we specialize in:

UH Ahuja Medical Center offers direct access to the same multidisciplinary team of specialists, advanced technology and full range of medical resources available at UH Neurological Institute, based at University Hospitals Cleveland Medical Center. Learn moreabout the services provided at University Hospitals Neurological Institute.

Continue reading here:
Neurosurgery & Neurology Services| UH Ahuja Medical Center ...

Special Topics in Water Resources Planning and Management Graduate Community and Regional Planning -- Water management is complicated and highly contentious. This course evaluates various aspects of water resources including quality, flooding, supply and allocation and the... read more Landscape Architecture Design Studio I - VI Undergraduate Landscape Architecture and Horticulture -- Refer to department. People, Places and Environment Undergraduate, General Education Community and Regional Planning 0807 Have you ever thought about the relationship people have to their place-home, neighborhood, town, or city? How about to the environment? Have you ever thought about how people... read more Sustainable Design Undergraduate, General Education Landscape Architecture and Horticulture 0841 What's the big deal about global warming and how should we respond to it? Explore the issues and underlying causes. See how contemporary designers from Germany, Netherlands, UK... read more Green vs. Grey Urban Ecology Undergraduate, General Education Landscape Architecture and Horticulture 0852 Using Philadelphia as Living Laboratory, Learning about urban ecology, work required to planting, explore park infrastructure, vacant lot revitalization, and community gardens. Fundamentals of Horticulture Undergraduate Landscape Architecture and Horticulture 1001 Principles of horticultural science; basic techniques of horticulture, including soil management, plant propagation, selection and maintenance of plant materials, and landscape... read more Natural and the Built Environment Undergraduate Landscape Architecture and Horticulture 1013 An introduction to the interrelated disciplines of Landscape Architecture, Horticulture, Planning, and Architecture. Explores existing and natural site conditions and their impact... read more Intro To Community & Regional Planning Undergraduate Community and Regional Planning 1017 Theory and practice of urban planning in the United States. Discussion of planning policy, methodology, and implementation in such areas as land use, housing, environment,... read more Plant Ecology Undergraduate Landscape Architecture and Horticulture 1112 The structure and function of plants are studied in relationship to their fit into the environment. The interaction of plants with each other and with their environment through... read more Woody Plants I Undergraduate Landscape Architecture and Horticulture 1211 The study of native and introduced trees, shrubs, and vines that are the foundation of our natural and designed landscapes with emphasis on identification, culture, association in... read more Woody Plants II Undergraduate Landscape Architecture and Horticulture 1212 Continuation of the study of native and introduced trees, shrubs, and vines that are the foundation of our natural and designed landscapes with emphasis on identification, culture... read more Urban Form & Design Undergraduate Community and Regional Planning 2114 Basic design principles, techniques, and practices of sustainable urban form and design. The topics for most readings, projects, and guest lectures are people oriented and examine... read more Land Use Planning Undergraduate Community and Regional Planning 2166 At the heart and soul of community and regional planning is land use. How we use land and the institutional and legal basis by which we establish and implement land use goals are... read more Environmental Planning Undergraduate Community and Regional Planning 2213 A comprehensive overview of physical and environmental systems, including land, air, and water, and how planning can be conducted to protect such systems. Topics include... read more Herbaceous Plants I Undergraduate Landscape Architecture and Horticulture 2221 The identification, culture, and appropriate designs for native and cultivated annuals, perennials, bulbs, and wildflowers; collaboration with nature in designing and maintaining... read more Herbaceous Plants II Undergraduate Landscape Architecture and Horticulture 2222 Topics include: identification, culture, and creation of environmentally appropriate designs for native and cultivated annuals, perennials, herbs, and roses; cost analysis;... read more Landscape Engineering I - III Undergraduate Landscape Architecture and Horticulture 2241, 2242, 3243 Emphasizes the basic concepts, ideas, and techniques that deal with the visual, functional, and ecological aspects of grading and landform manipulation. Introduction to the... read more Sustainable Food Systems Planning Undergraduate Community and Regional Planning 2251 Planners are paying attention to the notion of food system planning: farm land preservation and environmental stewardship; economic development including distribution, processing... read more Food Crops I Undergraduate Landscape Architecture and Horticulture 2334 An introductory hands-on course in sustainable food production, handling, and distribution of crops. Food tasting is an integral part of this course. Food Crops II Undergraduate Landscape Architecture and Horticulture 2335 Hands - on course in organic food production, emphasis is on managing and harvesting crops. Students cultivate, manage and harvest their own vegetable/fruit garden. Geographic Information Systems Undergraduate Community and Regional Planning 2524 Basic principles and techniques of GIS, a computer-based system that uses spatial (geographic) data to analyze and solve real-world issues. Lab exercises, exams, and projects... read more Water Design in the City Undergraduate Landscape Architecture and Horticulture 2754 Cities throughout history have thrived or failed because of water. Every society's ability to secure its water supply, clean stormwater, and address flooding issues impacts the... read more Summer Field Ecology Undergraduate Landscape Architecture and Horticulture 2758 Students learn to "read" the landscape through the exploration of the landscape provinces of the Delaware River Basin. Through visiting landscapes in each of the sub-regions, they... read more Applied Plant Physiology Undergraduate Landscape Architecture and Horticulture 3122 Highlights the major environmental factors that affect plant growth and development and explores ecologically sound approaches to solving stress-related problems. Focuses on... read more Ecological Planning and Development Undergraduate Community and Regional Planning 3155 The fundamentals of the ecological planning method developed by landscape architect and regional planner, Ian McHarg, establish a basis to plan and develop both individual... read more Sustainability in Suburban Communities Undergraduate Community and Regional Planning 3255 The physical forms of suburban communities and the social and economic patterns that shape residents' lives make achieving sustainability in suburbia challenging and problematic.... read more Sustainable Community Design and Development Undergraduate Community and Regional Planning 3256 Introduces students to the concept of sustainable development and how it has been applied to the design and development of communities. Beginning with an examination of the... read more Planting Design Undergraduate Landscape Architecture and Horticulture 3345 Considers the integration of plants into the design process and emphasizes scale, development density, natural site characteristics, natural plant associations, and individual... read more Applied Entomology Undergraduate Landscape Architecture and Horticulture 3423 In lecture and laboratory, students learn the basic diagnostic skills for identifying pest problems. Integrated Pest Management (IPM) is emphasized as the approach for managing... read more Applied Plant Pathology Undergraduate Landscape Architecture and Horticulture 3424 Explores plant pathological theories and practices. The causes of plant diseases, such as fungi, bacteria, virus, nematodes, plant parasites, as well as environmental stresses,... read more Landscape Restoration Undergraduate Landscape Architecture and Horticulture 3514 Develops an ecologically based understanding of how to establish, restore, and manage meadows, forest, and wetland systems. Emphasizes natural processes and integrating the built... read more Landscape Management Undergraduate Landscape Architecture and Horticulture 3523 Develops an understanding of issues of professional, innovative, and appropriate landscape management. Major focus is given to site analysis, pruning, nutrition, water management... read more Internet and Digital Technologies for Community Engagement Undergraduate Community and Regional Planning 3555 Emerging technologies are directly influencing the planning and management of our urban areas in very profound and pervasive ways. Planning and related professionals increasingly... read more Intro to Emergency Planning Undergraduate Community and Regional Planning 3755 Provides a fundamental understanding of the emergency planning process, the phases of emergency management, and the roles and responsibilities of all parties involved. Students... read more Sustainable Community Design and Development Graduate Community and Regional Planning 5256 Introduction to the evolution, theory, and practice of planning for sustainable communities. Students evaluate recent conceptions of sustainable development, building an... read more Planning Theory Graduate Community and Regional Planning 8013 Provides the base knowledge of planning theory that serves as a springboard into more advanced courses in this degree program. 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Students are required to draw on and implement knowledge about wetland ecosystems to develop a... read more Public Lands Studio Graduate Landscape Architecture and Horticulture 8153 Material presented in LARC 8352: Policies of Public Design Seminar is addressed in this design studio, which focuses on a public project, such as a metropolitan park or regional... read more Environmental Planning Graduate Community and Regional Planning 8213 Environmental issues and concepts faced by planners and the methods used to address them. Applying principles of natural science disciplines to the analysis of man`s physical... read more Sustainability in Suburban Communities Graduate Community and Regional Planning 8255 The physical forms of suburban communities and the social and economic patterns that shape residents' lives make achieving sustainability in suburbia challenging and problematic.... read more Environmental Policy Graduate Community and Regional Planning 8257 This course identifies the complexities associated with environmental politics and management from both national and international perspectives. The first part of the course... read more Aesthetics Ecology Design Seminar Graduate Landscape Architecture and Horticulture 8351 Students learn about the emerging aesthetic associated with ecological design. Form and psychological experience of design are presented through readings and discussion. 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Explores the influences of... read more Integrated Transportation and Land Use Planning Graduate Community and Regional Planning 8656 Context-sensitive design seeks to blend transportation functions with other human activities and land-use characteristics. Often transportation and land-use decisions have worked... read more Non-motorized Transportation Planning Graduate Community and Regional Planning 8657 Transportation planning in the United States has long focused on improving conditions for motorized travel, primarily by personal cars and light duty trucks. The effects of an... read more NE Woodland Ecosystem Graduate Landscape Architecture and Horticulture 8751 The course presents terrestrial forest ecosystems and the biotic and abiotic factors that affect them. Students learn the components of forest ecosystems, including degradation... read more Wetland Ecology Graduate Landscape Architecture and Horticulture 8752 Refer to department. 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It includes strategies... read more Capstone Restoration Design Project Graduate Landscape Architecture and Horticulture 9995 Refer to department.

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Available Courses | Office of Sustainability

ColumbiaDoctors neurologists are among the most renowned neurology experts in the world. Neurology and neurosurgery services atNewYork-Presbyterian/Columbia University Medical Center continuously rank among the top programs in the nation, and the Department of Neurology is ranked #2 for NIH-funded research. Patients choose ColumbiaDoctors Neurology, at the famed Neurological Institute of New York or any of our six other convenient locations, for the finest neurological care available.

As one of the largest programs in the country, representing all subspecialties of Neurology, ColumbiaDoctors Neurology offers special expertise in the full range of neurological disorders. Patients who need an initial diagnosis, a second opinion or ongoing care for a wide variety of both chronic and acute neurological disorders will find help and hope with our caring and compassionate providers. Most of our clinicians are also involved in laboratory-based research and clinical trials, offering patients the newest therapeutic options and diagnostic tools.

For your scheduling convenience, ColumbiaDoctors Neurology has implemented a Same Day Neurology Program for new patients! First-time patients who call 646-426-3876 (646-42-NEURO) before 11:00 am are offered a same-day appointment with one of our general neurological specialists from the Division of Multispecialty Neurology. New patients calling after 11:00 am are offered a next day appointment. We offer patients requesting a particular neurologist the soonest available appointment or place them on a waitlist for appointments 10 or more days out.

Our neurological specialties include:

ColumbiaDoctors Neurology Aging and Dementia specialists provide comprehensive, coordinated care for those affected by aging, memory, or related behavioral disorders, including mild cognitive impairment, Alzheimer's disease, Creutzfeldt-Jakob disease, Lewy Body disease, Frontotemporal degeneration, and other less common disorders. Our multidisciplinary team of subspecialty-trained neurologists, neuropsychologists, psychiatrists, genetic counselors, social workers, nurses and other healthcare professionals work together to identify the exact cause of the patient's impairment and advise the patient and his or her family on the best treatment plan for the specific condition.

ColumbiaDoctors Neurology specialists within the Eleanor and Lou Gehrig ALS Center provide comprehensive care to individuals and families with ALS, PLS, and related forms of motor neuron disease (MND). Our ALS physicians and associated healthcare professionals form a multidisciplinary team that offers compassionate care to ALS/MND patients and families and provide the resources necessary to meet the evolving challenges of living with motor neuron disease. Research activities - including clinical trials and genome analysis - are integrated into the ALS Center clinics to give individuals the chance to participate in the fight against ALS/MND. Our personalized approach to patient care values knowledge, understanding, and hope.

The Comprehensive Epilepsy Center team at ColumbiaDoctors Neurology is dedicated to the evaluation and care of patients with epilepsy. We provide state-of-the-art medical and surgical treatment for managing epilepsy in adults, adolescents, and children, with the goal of helping patients gain control of seizures and improve their quality of life. Patients with epilepsy, particularly those with difficult to treat seizures or special issues such as pregnancy, memory, mood, or sleep disorders, will receive cutting-edge care in our center.

ColumbiaDoctors headache and facial pain neurologists have subspecialty training in diagnosing, treating and managing headache and facial pain disorders, in both adults and children. Together, our neurological experts work within an integrated team of pain management specialists, pain psychologists, oral and maxillofacial surgeons, neurosurgeons, and physical medicine specialists to address both common as well as rare intractable headache and facial pain disorders.

ColumbiaDoctors neurologists in the Multiple Sclerosis Clinical Care & Research Center lead a world-class treatment and research facility devoted to exemplary patient care and ground-breaking clinical research for multiple sclerosis and related autoimmune disorders. Our team gives patients comprehensive, coordinated access to a full array of neurological, rehabilitative, and psycho-social services to meet the specific needs of patients with MS.

ColumbiaDoctors Multispecialty Neurology Practice is composed of a coordinated team of neurological specialists with particular expertise in diagnosing and treating both common and complex neurological disorders.

ColumbiaDoctors Neuromuscular Medicine specialists provide comprehensive, multidisciplinary clinical care and advanced electrophysiological diagnostic testing for a broad spectrum of both adult and pediatric neuromuscular disorders. Subspecialty centers and programs within our Division of Neuromuscular Medicine include the Eleanor and Lou Gehrig ALS Center, the Peripheral Neuropathy Center, and the MDA Clinic and H. Houston Merritt Center for Inherited Myopathies and Mitochondrial Diseases.

ColumbiaDoctors Neuro-Oncology specialists provide expert, coordinated care and support to those diagnosed with a brain or central nervous system tumor. Our multidisciplinary team of neuro-oncologists, nurse practitioners and experienced healthcare professionals integrate all aspects of patient care, drawing upon the expertise of highly trained and experienced specialists and other health professionals, to give patients the most current, cutting-edge care and treatment options.

ColumbiaDoctors Neuropsychology Service provides comprehensive neuropsychological testing to diagnose or rule out various conditions in patients and to describe their impact on a person's cognitive functioning. Our tests are tailored to meet the specific needs and concerns of each patient.

Every member of ColumbiaDoctors Neurology movement disorders team is not only specially trained in the care of patients with movement disorders, but also conducts cutting-edge research that advances our knowledge of these complex neurological diseases. Our center is world-renowned for excellence in both clinical care and research related to Parkinson's disease and other movement disorders.

ColumbiaDoctors Neurology has several neurologists who specialize in the diagnosis and treatment of peripheral neuropathies. This group of disorders typically result from damage to the nerves responsible for sending information between the brain, the spinal cord, and the rest of the body. We deliver comprehensive studies, including nerve conduction and advanced treatment options to help a patient best understand his or her diagnosis and treatment options.

ColumbiaDoctors Neurology Sleep Disorder neurologists have expertise in the diagnosis and treatment of sleep disorders, from the common to the complex. We specialize in sleepdisorders (including sleep apnea) in patients with neurologic and/or psychiatric disease. ColumbiaDoctors Neurology offers a range of sleep assessment options, such as testing done during an office visit, overnight studies in our sleep lab, and at-home sleep assessment options.

ColumbiaDoctors Neurology stroke and cerebrovascular disease experts create a continuum of care to minimize damage and give a patient the best chance of survival and quality of life after a stroke. We conduct cutting-edge clinical, epidemiological, and basic science investigations on stroke and cerebrovascular disease making sure our patients receive state-of-the-art care. NewYork-Presbyterian Hospital at Columbia University Medical Center is a major referral center for patients with strokes, guiding the care of patients from other medical centers in the area and in the nation.

ColumbiaDoctors Neurology offers a wide range of advanced diagnostic and treatment services to address each individual patients needs. These include:

ColumbiaDoctors Neurology locations are conveniently located in and around the New York City area:

ColumbiaDoctors Neurology - The Neurological Institute of New York710 West 168th StreetNew York, NY 10032

ColumbiaDoctors Neurology - Midtown51 West 51st Street, Suite 380New York, NY 10019ColumbiaDoctors Child Neurology - Harkness Pavilion180 Fort Washington Avenue, 5th FloorNew York, NY 10032

ColumbiaDoctors Neurology Riverdale3050 Corlear AvenueBronx, NY 10463

ColumbiaDoctors Neurology Westside Pediatrics21 West 86th StreetNew York, NY 10024

ColumbiaDoctors Neurology - Tarrytown155 White Plains RoadTarrytown, NY 10591

Read more here:
Neurology | ColumbiaDoctors

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In this new business intelligence report, Interventional Neurology Device Market Research serves a platter of market forecast, structure, potential, and socioeconomic impacts associated with the global Interventional Neurology Device market. With Porters Five Forces and DROT analyses, the research study incorporates a comprehensive evaluation of the positive and negative factors, as well as the opportunities regarding the Interventional Neurology Device market.

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Interventional Neurology Device Market: Business Opportunities, Current Trends and Industry Analysis by 2037 - Packaging News 24

Emotional issues, fatigue, and difficulties in thinking represent common symptomatic themes in patients with Huntington disease (HD), according to a study published in Neurology.

Patients with manifest HD and prodromal HD (n=20), as well as caregivers of patients with HD (n=20) were included in this international cross-sectional survey study. Researchers conducted qualitative interviews that asked participants about symptoms of HD that had the greatest impact on their lives. Patterns in responses were recorded to identify relevant symptoms across the population. A cross-sectional study was also performed with 156 patients with HD and 233 caregivers. In this study, the researchers examined both the prevalence and importance of 216 symptoms and 15 symptomatic themes in the disease.

Symptomatic themes in this study were defined as concepts that represented a group of like symptoms. In study participants with HD, the most prevalent symptomatic themes included emotional issues (83.0%), fatigue (82.5%), and difficulty thinking (77.0%). As assessed by the average life impact scores, the symptomatic themes associated with the highest relative importance to patients with and caregivers of HD included difficulty thinking (1.91), impaired sleep or daytime sleepiness (1.90), and emotional issues (1.81).

Conversely, the researchers observed a lower prevalence of symptomatic themes in patients who were employed, had High Total Functional Capacity scores, and had prodromal HD. Patients with HD had relatively high rates of emotional issues (71.2%) and fatigue (69.5%), despite these patients having no clinical features of HD.

Patients with manifest HD and caregivers of patients with HD did not participate in the survey as matched pairs, which represents a potential limitation of the study. Another limitation of the study was the self-reported nature of the Total Functional Capacity score and the lack of external validation by a clinician.

The researchers concluded that the knowledge gained of these symptoms is relevant for those in the process of developing experimental therapeutics for those with HD and for those who wish to better explore the symptomatic burden of this population.

Disclosure: Several study authors declared affiliations with the pharmaceutical industry. Please see the original reference for a full list of authors disclosures.

Reference

Glidden AM, Luebbe EA, Elson MJ, et al. Patient-reported impact of symptoms in Huntington disease: PRISM-HD [published online March 19, 2020]. Neurology. doi: 10.1212/WNL.0000000000008906

Here is the original post:
Patients With Huntington Disease Frequently Report Emotional Issues, Fatigue, and Difficulty Thinking - Neurology Advisor

Neurology is the branch of medicine that involves the nerves and nervous system. Neurologists at Summit Medical Group provide comprehensive care for a wide variety of adult neurological disorders, including diseases of the brain, spinal cord, nerves, and muscles.

Our facility is equipped with state-of-the-art imaging, including magnetic resonance imaging (MRI), carotid ultrasound, computed tomography (CT) scans, and electroencephalograph (EEG) testing. We also can take and submit blood work for laboratory testing, administer infusions and epidural injections, and perform physical therapy.

Common nervous system disorders that a neurologist can diagnose and treat include:

Strokes Damage to part of the brain when its blood supply is suddenly reduced or stopped. A stroke also is called a cerebral vascular accident or CVA. The part of the brain deprived of blood dies and can no longer function properly.

Epilepsy (seizures) A condition caused by brief, strong surges of electricity that affect all or part of the brain. Seizures can impact physical and mental health.

Headaches Pain in the upper neck and head that varies in severity and frequency. Headaches occur from a wide range of causes.

Dementias such as Alzheimers disease A gradual loss of mental functions such as the ability to think, remember, reason, and plan.

Multiple sclerosis A disease of the central nervous system (the brain and spinal cord) that causes loss of coordination and muscle control.

Parkinsons disease A disease that occurs when some of the nerve centers in the brain lose the ability to control muscle movement. The condition can result in rigid muscles, tremors, and difficulty with walking and swallowing.

Various forms of pain Neuropathic pain can result from injury or damage to the nerves.

Neurologists at Summit Medical Group are highly qualified and have extensive training and clinical experience. In addition, they have taught courses in some of the nations top academic centers.

Summit Medical Group neurologists are experts in:

See experts at our Go Red Day: Heart Disease and Stroke Awareness Expo discuss important ways you can protect your health.

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Neurology | Summit Medical Group

Elanco Animal Health (Credelio)

"Weve worked diligently to communicate the class change to veterinarians and also feature specific language on seizures in our Credelio advertisements. Also, FDA did not determine the final language re: seizure risk until after Credelio was approved. So, Elanco included the following language in the Credelio label with approval from the FDA: 'Use with caution in dogs with a history of seizures' at time of product approval."

"Nothing is more important to Merck Animal Health than the safety and efficacy of our products and the well-being of animals. We continue to encourage all pet owners to speak to their veterinarian before making any decisions about flea and tick control products. Parasites like fleas and ticks are not only a nuisance for pets and their owners, but if left untreated they can transmit serious diseases to pets.

It is important to note that the FDA updated the labeling for the entire class of isoxazoline drugs in September of 2018.

Pet-owner product materials, including advertising, displays and brochures have been updated with the new safety information.

Merck Animal Health is confident in the safety and efficacy of our products such as Bravecto and follow all legal and regulatory requirements. The safety and efficacy of Bravecto has been established through comprehensive research in more than 170 clinical research studies. In addition, more than 125 million doses of Bravecto have been distributed in 85 countries. The overall worldwide reporting rate for adverse events for our products containing isoxazoline remains classified as rare."

"In September 2018, the U.S. Food and Drug Administrations (FDA) Center for Veterinary Medicine (CVM) released a public communication to pet owners and veterinarians regarding the use of flea-and-tick-control products within the isoxazoline class of drugs. In this announcement, the FDA reported receiving reports of neurological signs in some dogs and cats following the use of products within the class. CVM issues these communications to veterinarians and pet owners to aid in making decisions about animal health products.

NexGard is an oral, beef-flavored soft chew that is administered monthly to dogs. It contains the active substance afoxolaner, a compound in the isoxazoline class, for the treatment and prevention of flea infestations and the treatment and control of ticks in dogs for one month. NexGard is approved by regulatory authorities for use in more than 100 countries, with more than 330 million doses sold worldwide. While the FDA notes that reports involving neurological signs have been reported for all isoxazoline products, they remain very rarely reported with NexGard (very rare defined as The most commonly reported adverse events in the US are vomiting, pruritus, lethargy, diarrhea, and anorexia. The NexGard label was updated with the information that the FDA described in their announcement.

The efficacy and safety of our products are paramount, and we believe that it is important for veterinarians and pet owners to be aware of any potential risks associated with products used in pets. As with any veterinary product, we recommend that pet owners discuss with their veterinarian before using a product."

"Zoetis colleagues, many of us pet owners, care about the well-being of pets, and we are committed to providing safe and effective products to veterinarians, pet owners and the animals in their care. We all sympathize with the frustration and concerns of pet owners when their pets are sick.

Our product Simparica (sarolaner) Chewables is one of four tick and flea medications for dogs in the isoxazoline class currently on the market. The labeling for Simparica is approved by the FDA. The product label and all of our promotional materials have always included information about neurologic signs such as tremors, unsteadiness, and/or seizures that have been associated with use of medicines in the isoxazoline class in some dogs.

Our product labeling for Simparica was approved by the FDA and updated in June 2019 to reflect their comments on neurologic events. Here is the website with prescribing and safety information for Simparica. You can click through from here for more detailed information that is shared in the packaging as well. https://www.zoetisus.com/products/dogs/simparica/prescribing-information.aspx

We are confident that Simparica, which has been sold in the U.S. for 4 years, remains an effective and safe tick and flea option for dogs. The overall global reporting rate for any clinical sign reported for Simparica (including vomiting, lethargy, diarrhea or any neurologic sign), is classified as very rare as defined by international regulatory authorities as less than 1 report per 10,000 doses administered (This rate was calculated based on all reports regardless of any causal relationship to the product). Simparicas adverse event profile continues to be predictable and consistent with pre-approval studies and looks similar to other isoxazoline products on the market.

We focus on ensuring veterinarians have the proper education, prescribing and safety information to share with pet owners, so that they can best advise each pet owner which products are the best choice for their individual pet and best suited to each pets medical needs. We also encourage pet owners to have regular conversations with veterinarians about their pets health.

Unfortunately, all medicines come with some potential risks and side effects and that is why their use should always be taken in consultation with a veterinarian. For the vast majority of pets, tick and flea medicines are safe, effective and help greatly reduce health risks that can come from parasites, such as Lyme disease, anemia and other infectious diseases. These are serious health concerns for all dogs and regular use of tick and flea medicines is recommended by veterinarians throughout the United States.

Revolution Plus for cats is also an isoxazoline product (sarolaner) and was approved in the U.S. in 2018 and launched there in 2019. Simparica was approved in launched in the U.S. in 2016."

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Flea and tick medication companies respond to 5 On Your Side - WRAL.com

In this weeks DocWire Homepage news: The CDC confirms the first possible case of COVID-19 community spread in America; mistreatment in medical school is more common among women, minority, and LGB students; brain iron may predict the onset of dementia in patients with Parkinsons disease; and find out what rare condition a Stranger Things actor has helped raise public awareness on.

This week, the Centers for Disease Control and Prevention (CDC) confirmed an infection of theWuhan coronavirus, COVID-19, in California in a person who reportedly did not have any relevant travel history to an area affected by the outbreak, nor did they have exposure to a known patient with the virus. This development comes after the CDC warned Americans on Tuesday to prepare for an imminent COVID-19 spread in the U.S., saying its not a matter of if, but when.The CDC noted that the federal government is currently working closely with state, tribal, and territorial partners to mitigate the spread of COVID-19, which hasnow killedat least 2,800 people worldwide.

CDC Confirms First Possible Instance of COVID-19 Community Spread in U.S.

The findings of a new study suggest that female, underrepresented minority (URM), Asian, multiracial, and lesbian, gay, or bisexual (LGB) students seem to bear a disproportionate burden of the mistreatment inmedical school. Thestudy appearedinJAMA Internal Medicine. In this cohort study, they analyzed data from the 2016 and 2017 Association of American Medical Colleges Questionnaire, which annually surveys graduating students from all 140 accredited allopathic medical schools in the US. The results showed that mistreatment was more commonly reported by women, minority, and LGB students compared to their male, white, and heterosexual counterparts.

Study: Mistreatment in Medical School is More Prevalent Among Female, Minority, and LGB Students

Measures of iron in the brain might eventually predict dementia inpatients withParkinsons disease (PD), according to the findings of astudy publishedin theJournal of Neurology, Neurosurgery, and Psychiatry. In this study, the researchers analyzed 100 patients with early-to-mid stage PD along with 37 age-matched controls using an algorithm for assessing cognitive decline risk in PD. Subsequent to analysis, the results showed that iron accumulation in the hippocampus and thalamus brain regions are associated with poor memory and thinking scores in patients with PD. First author, PhD student George Thomas (UCL Queen Square Institute of Neurology), added that: Its really promising to see measures like this which can potentially track the varying progression of Parkinsons disease, as it could help clinicians devise better treatment plans for people based on how their condition manifests.

Measures of Brain Iron May Predict the Onset of Dementia in Patients with Parkinsons Disease

TheNetflixoriginal series,Stranger Things,has helped generate increased public awareness of the rare disorder cleidocranial dysplasia (CCD) thanks to actor Gaten Matarazzo III, according to the findings of aresearch letterpublished in JAMA Otolaryngology Head & Neck Surgery. Since the introduction of CCD onStranger Things,Matarazzo helped establish the foundation CCD Smiles to promote global awareness, provide dental care assistance, and support research.Through their expansive reach to the public and media connections, celebrities such as Matarazzo may serve as positive agents to raise awareness and educate the general public, the research authors wrote.

Stranger Things Actor Gaten Matarazzo III Has Increased Public Awareness of Cleidocranial Dysplasia

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This Week: First Possible Community Spread of COVID-19 in the U.S.; Stranger Things Actor Raising Public Awareness; and more - DocWire News