A doctor who loves night shifts

Emergency medicine physician, world-class educator and blogger extraordinaire Dr. Mike Cadogan was recently interviewed by Elsevier Australia:

Interviewer:

What are the best and worst parts of night shifts? Do you have any tips for surviving nights?

Mike Cadogan:

I love night shifts. The dark corridors, the cool air, the rising moon, the autonomy of decision-making, the authority, the midnight snacks and the sense of joyous achievement walking home with the sun rising and against the tide of tired, depressed faces gripping their morning coffees and bemoaning the need to be at work on such a glorious sunny day…

Think positive, be strong and enjoy autonomy. Remember that everybody else is on night shift with you, and most of them don’t want to be there either…but there is no need to be grumpy, rude, or pompous. Make friends with the night owls and collaborate, you will find your workload will dramatically decrease… Make enemies with the permanent night staff at your peril!

References

Interview with Mike Cadogan, author of the acclaimed On Call: Principles and Protocols by Student Ambassador Emma Sharp.
Image source: A halo around the Moon. Wikipedia, GNU Free Documentation License.

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Medical student about Kindle: those once 40-lb volumes are now in the pocket of my white coat

A medical student emailed the Kindle team: "What you have here is a great product. I am a third year medical student out of New York, and have loaded a bunch of my textbooks onto the Kindle. Those once 40lb volumes of ill-fated tree trunks, are less than a pound, and now in the pocket of my white coat. Really a great asset!"

A former law student commented: "If I had a Kindle in law school, I think I would be 2 inches taller, and not need glasses..."

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Insulin is one of the top 10 high risk medications worldwide for prescription errors

Insulin has been identified as one of the top 10 high risk medicines worldwide. Errors are common - the first national audit in England and Wales showed prescribing errors in 19.5% of cases.

Not only are mistakes common, they often lead to harm - 3% of medication errors are related to insulin, but these errors were also twice as likely to cause harm as errors for other prescribed drugs.

Errors relating to insulin arise because insulin has a narrow therapeutic range and requires precise dose adjustments with careful administration and monitoring.

Over 20 different types of insulin are in use, in various strengths and forms, and with a range of delivery devices, including insulin syringes (from vials), insulin pens (prefilled or reusable), or infusion pumps.

References:

Safer administration of insulin: summary of a safety report from the National Patient Safety Agency. BMJ 2010; 341:c5269 doi: 10.1136/bmj.c5269 (Published 13 October 2010).

Image source: Wikipedia, public domain.

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Ads for Target in-store clinic

Target pushes hard the ads for its in-store clinics - 4 of them in the Sunday edition of The Chicago Tribune:

Walmart is also entering the field of NP-staffed clinics in a major way, followed by CVS Pharmacy:

Walmart has been adding health clinics to its stores during the last 3 years as part of its drive for "one-stop shopping." There were 100 in-store clinics in 21 states in 2010.

In fact, Minute Clinic is the largest retail clinic chain in the country, with 600 clinics in CVS stores in 24 states. Almost half of Minute Clinic's clientele don't have a primary-care doctor of their own.

Comments from Twitter:

@napernurse: Pharm son works for #Walgreens. Costs them $5 to be seen by NP for whatever 🙂 Can just walk-in & now WAG on "Blue Button" campaign.

Related:
"The Clinic" at Walmart - Operated by "Family Medicine Specialists"

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New Complication from Contaminated Cocaine – Bilateral Necrosis of the Ear Lobes and Cheeks

Interesting fact: Traces of cocaine taint up to 90% of paper money in the United States. Paper money become contaminated with cocaine during drug deals and directly through drug use, such as snorting cocaine through rolled bills. Amounts of cocaine found on U.S. bills ranged from 0.006-1,240 micrograms of cocaine per banknote (50 grains of sand) (http://bit.ly/27V5Yt).

Since 2005, levamisole (commonly used as to treat worm infections in humans and animals), has increasingly been used to mix cocaine for street use.

In 2009, 70% of cocaine seized at U.S. borders contained levamisole, causing an increase in cases of neutropenia among cocaine abusers.
Recently, researchers observed a new complication of levamisole contamination – vasculitis. Two cocaine abusers with similar cases of neutropenia and vasculitis presented to the University of Rochester Medical Center within 8 days of each other - with purplish plaques on their cheeks, earlobes, legs, thighs and buttocks. While the patients were not tested for levamisole levels, exposure was likely due to recent cocaine use.
Doctors should suspect levamisole exposure in patients presenting with both neutropenia and necrotic skin lesions.

See the dramatic photos from a similar case published in the NEJM here: Toxic Effects of Levamisole in a Cocaine User

References:
Bilateral Necrosis of Earlobes and Cheeks: Another Complication of Cocaine Contaminated With Levamisole. Ann of Int Med, June 1, 2010,  vol. 152  no. 11  758-759.

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Oral symptoms of systemic diseases – what to suspect?

Examination of the oral cavity (mouth) may reveal findings pointing to an underlying systemic condition, and allow for early diagnosis and treatment.
Oral examination should include evaluation for:
- mucosal changes
- periodontal inflammation and bleeding
- condition of the teeth
Examples of lesions:
- Oral findings of anemia may include mucosal pallor, atrophic glossitis, and candidiasis.
- Oral ulceration may be found in patients with lupus erythematosus (SLE), pemphigus vulgaris, or Crohn disease. Oral manifestations of lupus erythematosus may include honeycomb plaques (silvery white, scarred plaques); raised keratotic plaques (verrucous lupus erythematosus); erythema, purpura, petechiae, and cheilitis.
Oral findings in patients with Crohn disease may include diffuse mucosal swelling, cobblestone mucosa, and localized mucogingivitis.
- Diffuse melanin pigmentation may be an early manifestation of Addison disease.
- Periodontal inflammation or bleeding should prompt investigation of conditions such as diabetes mellitus, human immunodeficiency virus (HIV) infection, thrombocytopenia, and leukemia.
- In patients with gastroesophageal reflux disease (GERD), bulimia, or anorexia, exposure of tooth enamel to acidic gastric contents may cause irreversible dental erosion. Severe erosion may require dental restoration. 
- In patients with pemphigus vulgaris, thrombocytopenia, or Crohn disease, oral changes may be the first sign of disease.
References:
Oral manifestations of systemic disease. Chi AC, Neville BW, Krayer JW, Gonsalves WC. Am Fam Physician. 2010 Dec 1;82(11):1381-8.
Image source: Head and neck. Wikipedia, public domain.

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Burnout and Educational Debt Affect Medical Knowledge Among IM Residents (measured by exam scores)

Doctors are not impervious to stresses of daily life. Physician distress is common and has been associated with negative effects on patient care.

This JAMA study of internal medicine residents used data collected during 2008-2009 Internal Medicine In-Training Examination (IM-ITE). Participants were 16,000 IM residents, representing 74% of all eligible US internal medicine residents - approximately 7700 US medical graduates and 8500 international medical graduates (IMGs).

Quality of life was rated “as bad as it can be” or “somewhat bad” by 15% of residents.

Burnout, emotional exhaustion and depersonalization were reported by 51%, 46%, and 29% of residents, respectively.

Burnout was less common among international medical graduates than among US medical graduates (45% vs 59%),

Greater educational debt was associated with the presence of at least 1 symptom of burnout (61% vs 44%; for debt greater than $200 000 relative to no debt).

Residents reporting QOL “as bad as it can be” and emotional exhaustion daily had exam scores 2.7 points and 4.2 points lower than those with QOL “as good as it can be” and no emotional exhaustion, respectively.

Residents reporting debt greater than $200,000 had exam scores 5 points lower than those with no debt.

Suboptimal QOL and burnout were common among IM residents. Burnout was associated with higher debt and was jess frequent among international medical graduates (IMGs).

Low QOL, emotional exhaustion, and educational debt were associated with lower IM-ITE scores.

References:

Quality of Life, Burnout, Educational Debt, and Medical Knowledge Among Internal Medicine Residents. JAMA, 2011;306(9):952-960. doi: 10.1001/jama.2011.1247
Stress overdose for doctors. Star Tribune.
Image source: OpenClipArt.org, public domain.

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Medical problems among prisoners

From a recent review in The Lancet:

More than 10 million people are incarcerated worldwide, and this number has increased by one million in the past decade.

Some of the major medical problems include:

- Mental disorders and infectious diseases are more common in prisoners
- High rates of suicide in prison
- Increased mortality on release

High risk groups among prisoners:

- women
- prisoners aged 55 years and older
- juveniles

References:
The health of prisoners. The Lancet, Volume 377, Issue 9769, Pages 956 - 965, 12 March 2011.
“A very severe physical trial”. The Lancet, Volume 377, Issue 9769, Page 876, 12 March 2011.

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Biobank – BMJ video

BMJ medical innovations: When it comes to doing epidemiological studies, numbers matter. We find out about the UK's biobank - a project to collect information and samples from 500,000 volunteers, which should help scientists look for links between lifestyle and health.

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One doctor prescribed more than a million hydrocodone tablets

A California diet center doctor known by patients as “Candy Man” was sentenced to four years in federal prison for dispensing what authorities said were massive amounts of powerful painkillers in exchange for cash.

Records revealed that he ordered more than a million hydrocodone tablets in 2008, more than any other doctor in the nation.

Prosecutors estimated that he made nearly $700,000 that year from selling controlled substances. However, authorities said they couldn’t account for 75% of the pills purchased over a 13-month period because he didn’t keep records of the transactions.

In the meantime, the NYTimes reports that Florida is shutting ‘Pill Mill’ clinics. Florida has long been the nation’s center of the illegal sale of prescription drugs: some doctors there bought 89% of all the Oxycodone sold in the country last year. This has changed dramatically with the introduction of new legislation.

References:
Doc gets 4 years for dispensing drugs for cash. MSNBC.
Florida Shutting ‘Pill Mill’ Clinics. NYTimes.
Image source: public domain.

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3,000 Pills Later – A Nutraceutical Experiment – TIME Video

The TIME magazine writer John Cloud took over 3,000 vitamins and supplements in a span of 5 months to see how his health would change. He was taking 28 pills a day. The results may surprise you.

He gained weight. His HDL increased but nobody was sure why. His vitamin D level increased but the follow-up level was done in June when he was spending more time in the sun anyway. That was all.

References:
Nutrition In a Pill. TIME.

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Should a doctor block his/her patients on Google+ or Twitter?

According to the Guardian newspaper, the current UK guidelines state that "Doctors must not "friend" their patients on Facebook."

Should a doctor block his/her patients on Google+ then? What about Twitter?

Social media platforms, their use, and the perception of the ways they are used are all changing. The ban of professional use of the most popular services is not the way forward.

Doctors are natural communicators and should do very well on social media platforms. Patients, and society in general, would only benefit from physicians who share ideas and focus on education.

Simple guidance for social media use
The suggested guidance for social media use by health professionals is very simple and based on a recent book by a nurse and social media advocate:
1. Remember the basics:
- your professional focus
- the laws around patient privacy (HIPAA in the U.S.)
- the professional standards of regulatory bodies and of your employers
2. After that, explore all the different social media tools that are out there:

The Cycle of Online Information (click to enlarge the image):

References:

Facebook friends a no-no for doctors. Guardian.
Doctors are natural communicators - social media is extension of what they do every day

Comments from Google+:

Steven Eisenberg - Create a circle of patients and share/filter as appropriate? Hmmmm... Thoughts?

Neil Mehta - In real life, what would you do if you run into a patient at a party? At a grocery store? Would BMA ask the docs to not talk with them? Turn their backs? Would that be professional? Do you ask you patients about their hobbies, interests travels? Does it help you become a more patient-centered provider?
Social Media is here to stay. Just as we have boundaries in RL we need to talk about appropriate boundaries in SoMe. The answer is probably use common sense and put the interest of the patient first. In some countries, it is routine practice to give your patient your cell phone number. So does the answer depend on your cultural and societal norms? It is a slippery slope and a number of issues need to be figured out - privacy, reimbursement, liability etc. What if the Social (professional) network exchange was behind appropriate firewalls/tunneled, what if the pts, PHR was accessible? What if we had a ACO model with no fee for service but the system was responsible for keeping their patients healthy?

Jeffrey Benabio, MD - Ves, here's the comment I put on David Lewis's post:

The difficulty is in how we define friends in this space. The doctor-patient relationship is unique and it's difficult (usually impossible) to have both a healthy friendship and healthy doctor-patient relationship without compromising both.

Patients depend on me, not as a friend, but as their physician. The expectations for a friend and a physician are different; it is difficult to have two sets of expectations for the same person.

As a physician, I'm privy to information that is personal, sometimes compromising, and often affects other people that both I and the patient knows. Patients must share things with me that they would never share with a friend. My duty as physician is only to care for her; if she and I were friends, then what she shared with me could be damaging to her in her social or personal life. I could not be both her friend and her physician.

Friends can also sometimes become romantic partners. This is verboten in a doctor-patient relationship.

The relationship between friends must be egalitarian and mutual. This is not true of doctor-patient relationships. I must advise patients what to do. I cannot tell my patients about my problems ("Boy you think that's a rash, look at this one on my leg!").

Their role as patient is to get and stay well. My role is to do everything in my ability to help them achieve that. They pay me to do this. They expect me to do this. There cannot be any reciprocity.

In fact, unlike friends, it's inappropriate for physicians to accept gifts from patients. Do patients who buy me a bottle of wine get special treatment? Do my "friend" patients have special access to me? Special privileges? It would be unfair to all my "non-friend" patients. This is where something innocuous in a friendship becomes unethical in medicine.

I examine, touch and sometimes hurt patients this is unique to medicine. Imagine that I must touch the genitals of a patient to treat him or her. This action has no place in a friendship and both the doctor-patient relationship the friendship would be compromised.

Imagine if a patient found that my political or religious beliefs were inconsonant with his beliefs. This could compromise my ability to be the best physician for him if he was unable to trust me because I was Jewish or Muslim or Catholic. This might force him to find a new physician at a time when he's sick or vulnerable and would compromise his ability to get the best care.

I have a great relationship with my patients; we are friendly and engage in enjoyable conversations about life, politics and the weather. But each of these relationships is a doctor-patient relationship that best serves the needs of the patient above all else.

The problem with social media friendships for physicians is that they're too close to real life friendships. All my online patient friends are "doctor-patient-friends" and I endeavor to keep it that way for their sake.

Steven Eisenberg - Jeffrey- SO well said. Very complex indeed.

Nancy Onyett, FNP-C - I totally agree with Jeffrey Benabio MD. The AMA and ANA for Advanced Practice has these points under the Code of Ethics for Professioal Conduct. Dr. Benabio breaks this down ito layman terms. Great post TY:)

Neil Mehta - Great discussion. Social Media (web 2.0) means a two way discussion as opposed to a static one way lecture (web 1.0). The facebook model is just one type of a social networking model which is one type of social media (medium). Seems professional bodies would not want us to "Friend" our patients and most people would agree. "Friend" is very much a FB term which has a connotation that means Friends see each others posts, photos, videos on Facebook. What do people think of doctor-patient communications using Online Social Media in the broad sense of the term?

Examples include:

A doctor posts some patient education material on YouTube that the patient sees and comments on.
What about the functionality of asymmetric circles? That prevents reciprocity.
We have seen how sending periodic SMS to pts with chronic conditions improves adherence. Is it possible to extend that model?

Nancy Onyett, FNP-C - I feel safer using my own EMR for patient correspondence through encrypted email. I am not sure if creating a circle of patients would be feasible unless it was for education and HIPPA/Privacy would not be violated --may be difficult to do.

Bader ALHablani - Great discussion...please allow me to ask a question here.Quote from the article: "Yet accepting Facebook friends presents doctors with difficult ethical issues," he said. "For example, doctors could become aware of information about their patients that has not been disclosed as part of a clinical consultation." End of quote. Suppose patient XYZ is one of my friends on Google+. And I am following Dr. ABC and vice versa. What would happen when I post an article (to my extended circles) and patient XYZ writes a comment/reply that contain an information which “could [make] Dr. ABC “aware of information about their patients that has not been disclosed as part of clinical consultation”, please? Dr. ABC would be able to see his/her comments, right please?

doc emer - I also have excellent friendship relationships with my online patient-friends in FB. I think it even helps in treatment/management. Problems may occur, as in any form of communicating, but are rare and isolated. A good doctor is friends with his patients, be it online or otherwise.

Michael Zelman - Psychologists have explicit rules about avoiding multiple relationships, being "friends" with patients falls under that category. The intent is to protect the patient and therapeutic relationship between client and professional. There are obvious parallels between physician and patient. This is not to say that every aspect of a social media relationship would be negative, but virtual friending can blur boundaries, change expectations, violate confidentiality, and lead to expectations of more out of the relationship than is healthy or allowed. It may be possible to navigate social media relationships while avoiding multiple relationships with a practitioner as a business; i.e., group practice, hospital, community clinic where patients and community members follow the entity (not individual), but in a 1-way, asymmetric manner as proposed above. Even with that much care is needed to protect patient rights under various Federal and State privacy laws.

http://www.apa.org/ethics/code/index.aspx

"3.05 Multiple Relationships

(a) A multiple relationship occurs when a psychologist is in a professional role with a person and (1) at the same time is in another role with the same person, (2) at the same time is in a relationship with a person closely associated with or related to the person with whom the psychologist has the professional relationship, or (3) promises to enter into another relationship in the future with the person or a person closely associated with or related to the person.

A psychologist refrains from entering into a multiple relationship if the multiple relationship could reasonably be expected to impair the psychologist's objectivity, competence, or effectiveness in performing his or her functions as a psychologist, or otherwise risks exploitation or harm to the person with whom the professional relationship exists.

Multiple relationships that would not reasonably be expected to cause impairment or risk exploitation or harm are not unethical.

(b) If a psychologist finds that, due to unforeseen factors, a potentially harmful multiple relationship has arisen, the psychologist takes reasonable steps to resolve it with due regard for the best interests of the affected person and maximal compliance with the Ethics Code.

(c) When psychologists are required by law, institutional policy, or extraordinary circumstances to serve in more than one role in judicial or administrative proceedings, at the outset they clarify role expectations and the extent of confidentiality and thereafter as changes occur. (See also Standards 3.04, Avoiding Harm, and 3.07, Third-Party Requests for Services.)

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Adult stem cell infusion to treat MS – collaboration trial between Cleveland Clinic and Case

Cleveland Clinic, University Hospitals Seidman Cancer Center and Case Western Reserve University are collaborating on a clinical trial designed to treat the debilitating effects of multiple sclerosis by using a patient's own adult stem cells.

Mesenchymal stem cells, or MSCs, are found in the bone marrow. More than 150 clinical trials are currently testing MSCs' ability to encourage tissue repair as a way to treat a variety of conditions such as osteoarthritis, diabetes, emphysema and stroke.

In this trial, a patient's MSCs are harvested at Case's University Hospital, cultivated in a special laboratory and then injected intravenously back into the patient at the Cleveland Clinic.

See the two videos below that describe the project - the first is from the Cleveland Clinic and shows one of the patients, the second is from Case and focuses on the researchers:

References:
Clinical trials using adult stem cells to treat MS. Cleveland Plain Dealer.

Related:

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Disease-Specific, Social Network-Initiated Study by Mayo Clinic and Dr. Tweet

Mayo Clinic is the clear leader in social media use by hospitals at this time. Mayo has published 1,500 YouTube videos, has a social media center with approximately 20 employees, and external advisory board with experts that span the globe. They have a social media "residency" program where (for a fee) they are ready to teach you how to blog, Twitter, Facebook and YouTube in 3.5 days. Unhappy with the Facebook use for healthcare, Mayo launched their own social network for patients. But why stop there? Mayo Clinic figured out that you can collect data from the clusters of patients with rare conditions that form spontaneously in social networks. This pilot study is a novel example of “patient-initiated research.” I think this is great and potentially very useful to patients and science. Let's hope more hospitals follow in the footsteps of these pioneers.

The two videos below illustrate the start of Disease-Specific, Social Networking Community-Initiated Study Focused on Spontaneous Coronary Artery Dissection (SCAD):

The chest pain experienced by the woman you're about to meet was much more than a difficult recovery. She had a heart attack when a rare and deadly condition stopped blood flow to her heart. The same thing happened to another woman. After sharing their stories on social networking sites they found more women with the same problem. That's when they contacted Mayo Clinic to convince cardiologists to use the information they gathered on the internet to research this condition.

Dr. Sharonne Hayes, Professor of Medicine in Cardiovascular Diseases at Mayo Clinic in Rochester, MN, discusses her article appearing in the September 2011 issue of Mayo Clinic Proceedings on using social media to research and treat spontaneous coronary artery dissection (SCAD).

After being approached by several members of an international disease-specific support group on a social networking site, the researchers used it to identify patients who had been diagnosed as having at least 1 episode of spontaneous coronary artery dissection and recruited them to participate in a clinical investigation of their condition. Medical records were collected and reviewed, the original diagnosis was independently confirmed by review of imaging studies, and health status (both interval and current) was assessed.

Recruitment of all 12 participants was complete within 1 week of institutional review board approval. All participants completed the study questionnaires and provided the required medical records and coronary angiograms and ancillary imaging data.

This study involving patients with spontaneous coronary artery dissection demonstrates the feasibility of and is a successful model for developing a “virtual” multicenter disease registry through disease-specific social media networks to better characterize an uncommon condition. This study is a prime example of patient-initiated research that could be used by other health care professionals and institutions.

A cute factoid? The lead author of this social network-initiated study is actually called Dr. Tweet (as in a message on Twitter).

References

Electronic Communication and Medical Research: Beyond the Record

Spontaneous Coronary Artery Dissection: A Disease-Specific, Social Networking Community–Initiated Study

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The diabetes pandemic: 1 in 4 U.S. adults now has diabetes

The number of adults with diabetes has doubled within the past 30 years.

70% of the increase is attributed to population growth and ageing. However, the number also reflects the unfortunate global shift towards a western lifestyle of unhealthy diet and physical inactivity, with obesity as the outcome.

Between 1980 and 2008, the global body-mass index (BMI) increased by 0·4—0·5 kg/m2 per decade.

In the USA, 10% of infants and toddlers already carry excess weight. More than 20% of children between the ages of 2 years and 5 years are overweight or obese.

By 2030, the number of individuals with diabetes worldwide is expected to rise to half a billion (470 million) - almost 80% of whom will be in low-income and middle-income countries. In these regions, diabetes drugs and insulin are often inaccessible or are too expensive.

References:
The diabetes pandemic. The Lancet, Volume 378, Issue 9786, Page 99, 9 July 2011.
Image source: Wikipedia, public domain.

Related from Amazon - pancreas plush toy:

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AMA Guide to Assessing and Counseling Older Drivers

Motor vehicle injuries are a leading cause of injury-related deaths in the older population (persons 65 years and older). Per mile driven, the fatality rate for drivers 85 years and older is 9 times higher than the rate for drivers 25 to 69 years old.

Physicians play an important role in the safe mobility of their older patients. The AMA encourages physicians to make driver safety a routine part of their geriatric medical services and the guide is freely available as PDF documents here:

AMA Physician's Guide to Assessing and Counseling Older Drivers

For example, dementia is just one of the risks that older drivers face:

Evaluation of driving risk in dementia (click to enlarge the image).

For patients with dementia, the following characteristics are useful for identifying
patients at increased risk for unsafe driving:

- Clinical Dementia Rating scale (Level A)
- caregiver’s rating of a patient’s driving ability as marginal or unsafe (Level B)
- history of crashes or traffic citations (Level C)
- reduced driving mileage or self-reported situational avoidance (Level C)
- Mini-Mental State Examination scores of 24 or less (Level C)
- aggressive or impulsive personality characteristics (Level C)

References:

AMA Physician's Guide to Assessing and Counseling Older Drivers

Evaluation of driving risk in dementia - practice parameter update

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Survival Guide – Chigoe Flea – National Geographic Video

Survival Guide - Chigoe Flea - National Geographic Video.

Tunga penetrans is hyperendemic in East Asia, India, and South America, where it originated, and in Sub-Saharan Africa, where it was introduced from South America in the late 19th century.

Tungiasis is caused by the penetration of the gravid female chigoe flea into the epidermis to feed on blood and tissue juices, usually on the feet and under the toenails or in the interdigital web spaces.

Management strategies for tungiasis include extracting all embedded fleas immediately with sterile needles or curettes, administering tetanus prophylaxis, and treating secondary wound infections with appropriate antibiotics. For heavy infestations with multiple lesions, oral therapy for 3 days with either thiabendazole or a single oral dose of niridazole (30 mg/kg) has been recommended.

References:

The Epidemiology, Diagnosis, Management, and Prevention of Ectoparasitic Diseases in Travelers. James H. Diaz MD, Dr PH. Journal of Travel Medicine, Volume 13, Issue 2, pages 100–111, March 2006.

Related reading:

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Persistent Sexual Side Effects Related to Finasteride (Popecia) Use for Male Hair Loss

Finasteride (Propecia) has been associated with reversible adverse sexual side effects in multiple trials for the treatment of male pattern hair loss (MPHL).

This study included 71 otherwise healthy men aged 21–46 years who reported new onset of sexual side effects associated with the temporal use of finasteride, and in which the symptoms persisted for 3 months despite the discontinuation of finasteride.

Patients reported the following new-onset persistent sexual dysfunction associated with the use of finasteride:

- 94% developed low libido
- 92% developed erectile dysfunction
- 92% developed decreased arousal
- 69% developed problems with orgasm

The mean duration of finasteride use was 28 months and the mean duration of persistent sexual side effects was 40 months from the time of finasteride cessation to the interview date.

Physicians treating MPHL should discuss the potential risk of persistent sexual side effects associated with finasteride

Minoxodil - Costco
Minoxodil - Costco.

References:

Persistent Sexual Side Effects of Finasteride for Male Pattern Hair Loss. Michael S. Irwig MD, Swapna Kolukula. The Journal of Sexual Medicine, 2011.

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Management of Hirsutism (Excess Hair)

Hirsutism is a source of significant anxiety in women. While polycystic ovary syndrome (PCOS) or other endocrine conditions are responsible for excess androgen in many patients, other patients have normal menses and normal androgen levels (“idiopathic” hirsutism).

The finding of polycystic ovaries on ultrasound  is not required for the diagnosis of polycystic ovary syndrome (PCOS). Gonadotropin-dependent ovarian hyperandrogenism is believed to cause PCOS. However, mild adrenocorticotropic-dependent adrenal hyperandrogenism also is a feature in many cases.

Even women with mild hirsutism can have elevated androgen levels, and thus, they may benefit from a laboratory evaluation.

Laser treatment does not result in complete, permanent hair reduction, but it is more effective than other methods such as shaving, waxing, and electrolysis. It produces hair reduction for up to 6 months. The effect is enhanced with multiple treatments. Interestingly, a portable laser hair removal device is currently available from Amazon (this post is not a recommendation or endorsement of the product).

References:
Update on the management of hirsutism. Cleveland Clinic Journal of Medicine June 2010 vol. 77 6 388-398.
Image source: Skin layers. Wikipedia, public domain.

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