MicroRNA: Keeping death in check

Recent research has illuminated a surprisingly important role for tiny RNA molecules, known as microRNAs, in downregulating the production of a variety of proteins and researchers have now teased out the role of microRNAs in managing p53 levels

A roundabout method of reading data can improve quantum memory

Researchers who hope to create quantum computers are currently investigating various methods to store data. Nitrogen atoms embedded in diamond show promise for encoding quantum bits (qubits), but the process of reading the information results in an extremely weak signal. Now physicists have demonstrated a roundabout approach for generating a significantly stronger signal from these sorts of qubits.

Quantum dot based siRNA approach selectively inhibits brain cancer cells

Oncogenes are genes that are associated with the development of cancer - when mutated or expressed at high levels, they can help turn a normal cell into a tumor cell. Promising new chemotherapeutic strategies have therefore focused on suppressing oncogenes. One such approach is based on RNA interference (RNAi), a technique wherein small double-stranded RNA molecules can sequence-specifically inhibit the expression of targeted oncogenes. The idea here is that with the help of small interfering RNA (siRNA), key oncogenes that modulate signaling pathways and thereby regulate the behavior of malignant tumor cells can be manipulated. To harness the full potential of this approach, the prime requirements are to deliver the siRNA molecules with high selectivity and efficiency into tumor cells and to monitor both siRNA delivery and the resulting knockdown effects at the single-cell level.

European collaboration makes breakthrough in developing graphene

A collaborative research project has brought the world a step closer to producing a new material on which future nanotechnology could be based. Researchers across Europe, including the UK's National Physical Laboratory (NPL), have demonstrated how an incredible material, graphene, could hold the key to the future of high-speed electronics, such as micro-chips and touchscreen technology.