Nanotechnology researchers develop color-changing stress sensor

It is helpful - even life-saving - to have a warning sign before a structural system fails, but, when the system is only a few nanometers in size, having a sign that's easy to read is a challenge. Now, thanks to a clever bit of molecular design by University of Pennsylvania and Duke University bioengineers and chemists, such warning can come in the form of a simple color change.

Connecting the dots – fused metal shapes on DNA origami

DNA origami is a design technique that is used by nanotechnology researchers to fold DNA strands into something resembling a programmable pegboard on which different nanocomponents can be attached. These DNA assemblies allow the bottom-up fabrication of complex nanostructures with arbitrary shapes and patterns on a 100 nm scale. For instance, DNA origami have been heralded as a potential breakthrough for the creation of nanoscale circuits and devices. DNA can also be metallized with different metals, resulting in conducting nanowires. Researchers have now have developed a method to assemble metallic nanocircuits with arbitrary shapes, by attaching metallic nanoparticles to select locations of the DNA origami and then fusing them to form wires, rings, or any other complex shape. These pre-designed structures are programmed by fully utilizing the self-assembling and recognition properties of DNA.