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jo lab

Our lab studies the mechanisms by which blood flow regulates endothelial biology and dysfunction, which leads to atherosclerosis and aortic valve calcification. In addition to in vitro (a cone-and-plate bioreactor) systems, the lab also developed an in vivomodel (a mouse partial carotid ligation model) in conjunction with OMICs approaches to understand how disturbed flow vs. stable flow differently regulate vascular and valve endothelial biology and pathobiology at the genome-, epigenome-, and metabolome-wide level.With these methods, we have been able to carry out several OMICs studies that have allowed us to identify mechanosensitive mRNAs, microRNAs, epigenetic DNA methylome, metabolites, and long non-coding RNAs (on-going work). These genome-, epigenome- and metabolome-wide OMICs studies have guided us not only to identify mechanosensitive genes, metabolites and epigenetic changes, but to demonstrate the critical role that some of these flow-sensitive molecular transducers play a role in controlling endothelial biology, atherosclerosis and aortic valve disease

Postdoctoral Fellow in Mechanobiology and Disease at Emory

A postdoctoral position is available immediately to study the mechanisms by which mechano-sensitive genes and epigenetics regulate vascular biology, atherosclerosis and aortic valve disease, and to develop gene-based therapies and targeted delivery methods in Coulter Department of Biomedical Engineering at Emory University in Atlanta, Georgia, USA. We are looking for a motivated and talented biomedical scientist or engineer with PhD or MD in related fields and with strong publication record. Please apply here: https://faculty-emory.icims.com/jobs/18016/job, and also send your CV by e-mail to Professor Jo. Applications will be reviewed on a rolling basis until filled but by June 10, 2018.

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jo lab

Nanomedicinelab

BioRxiv, posted online Aug. 1, 2018

2D Materials, 2018, 5: 035020

Journal of Controlled Release, 2018, 276: 157-167

ACS Nano, 2018, 12(2): 1373-1389

2D Materials, 2018, 5: 035014

Chem, 2018, 4(2): 334358

Nanoscale, 2018, 10:1180-1188

Advanced Healthcare Materials, 2017, 7 (4): 1700815

Science Robotics, 2017, 2, 12, eaaq1155

Nanoscale, 2018, 10, 12561264

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Nanomedicinelab

nanomedicine: nanotechnology for cancer treatment – YouTube

Solving radiotherapy s biggest limitation. Medicine is now using physics every day to treat cancer patients. Nanotechnologies or Nanomedicine can help clinicians deliver safer and more efficient treatments by shifting the intended effect from the macroscopic to the subcellular level. http://www.nanobiotix.comwww.laurentlevy.com

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nanomedicine: nanotechnology for cancer treatment – YouTube

Cryptocurrency News: XRP Validators, Malta, and Practical Tokens

Cryptocurrency News & Market Summary
Investors finally saw some light at the end of the tunnel last week, with cryptos soaring across the board. No one quite knows what kicked off the rally—as it could have been any of the stories we discuss below—but the net result was positive.

Of course, prices won’t stay on this rocket ride forever. I expect to see a resurgence of volatility in short order, because the market is moving as a single unit. Everything is rising in tandem.

This tells me that investors are simply “buying the dip” rather than identifying which cryptos have enough real-world value to outlive the crash.

So if you want to know when.

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Cryptocurrency News: XRP Validators, Malta, and Practical Tokens

Cryptocurrency News: Bitcoin ETFs, Andreessen Horowitz, and Contradictions in Crypto

Cryptocurrency News
This was a bloody week for cryptocurrencies. Everything was covered in red, from Ethereum (ETH) on down to the Basic Attention Token (BAT).

Some investors claim it was inevitable. Others say that price manipulation is to blame.

We think the answers are more complicated than either side has to offer, because our research reveals deep contradictions between the price of cryptos and the underlying development of blockchain projects.

For instance, a leading venture capital (VC) firm launched a $300.0-million crypto investment fund, yet liquidity continues to dry up in crypto markets.

Another example is the U.S. Securities and Exchange Commission’s.

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Cryptocurrency News: Bitcoin ETFs, Andreessen Horowitz, and Contradictions in Crypto

Cryptocurrency News: Looking Past the Bithumb Crypto Hack

Another Crypto Hack Derails Recovery
Since our last report, hackers broke into yet another cryptocurrency exchange. This time the target was Bithumb, a Korean exchange known for high-flying prices and ultra-active traders.

While the hackers made off with approximately $31.5 million in funds, the exchange is working with relevant authorities to return the stolen tokens to their respective owners. In the event that some is still missing, the exchange will cover the losses. (Source: “Bithumb Working With Other Crypto Exchanges to Recover Hacked Funds,”.

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Cryptocurrency News: Looking Past the Bithumb Crypto Hack

Cryptocurrency News: This Week on Bitfinex, Tether, Coinbase, & More

Cryptocurrency News
On the whole, cryptocurrency prices are down from our previous report on cryptos, with the market slipping on news of an exchange being hacked and a report about Bitcoin manipulation.

However, there have been two bright spots: 1) an official from the U.S. Securities and Exchange Commission (SEC) said that Ethereum is not a security, and 2) Coinbase is expanding its selection of tokens.

Let’s start with the good news.
SEC Says ETH Is Not a Security
Investors have some reason to cheer this week. A high-ranking SEC official told attendees of the Yahoo! All Markets Summit: Crypto that Ethereum and Bitcoin are not.

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Cryptocurrency News: This Week on Bitfinex, Tether, Coinbase, & More

Ripple Price Forecast: XRP vs SWIFT, SEC Updates, and More

Ripple vs SWIFT: The War Begins
While most criticisms of XRP do nothing to curb my bullish Ripple price forecast, there is one obstacle that nags at my conscience. Its name is SWIFT.

The Society for Worldwide Interbank Financial Telecommunication (SWIFT) is the king of international payments.

It coordinates wire transfers across 11,000 banks in more than 200 countries and territories, meaning that in order for XRP prices to ascend to $10.00, Ripple needs to launch a successful coup. That is, and always has been, an unwritten part of Ripple’s story.

We’ve seen a lot of progress on that score. In the last three years, Ripple wooed more than 100 financial firms onto its.

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Ripple Price Forecast: XRP vs SWIFT, SEC Updates, and More

Cryptocurrency Price Forecast: Trust Is Growing, But Prices Are Falling

Trust Is Growing…
Before we get to this week’s cryptocurrency news, analysis, and our cryptocurrency price forecast, I want to share an experience from this past week. I was at home watching the NBA playoffs, trying to ignore the commercials, when a strange advertisement caught my eye.

It followed a tomato from its birth on the vine to its end on the dinner table (where it was served as a bolognese sauce), and a diamond from its dusty beginnings to when it sparkled atop an engagement ring.

The voiceover said: “This is a shipment passed 200 times, transparently tracked from port to port. This is the IBM blockchain.”

Let that sink in—IBM.

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Cryptocurrency Price Forecast: Trust Is Growing, But Prices Are Falling

Cryptocurrency News: Vitalik Buterin Doesn’t Care About Bitcoin ETFs

Cryptocurrency News
While headline numbers look devastating this week, investors might take some solace in knowing that cryptocurrencies found their bottom at roughly $189.8 billion in market cap—that was the low point. Since then, investors put more than $20.0 billion back into the market.

During the rout, Ethereum broke below $300.00 and XRP fell below $0.30, marking yearly lows for both tokens. The same was true down the list of the top 100 biggest cryptos.

Altcoins took the brunt of the hit. BTC Dominance, which reveals how tightly investment is concentrated in Bitcoin, rose from 42.62% to 53.27% in just one month, showing that investors either fled altcoins at higher.

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Cryptocurrency News: Vitalik Buterin Doesn’t Care About Bitcoin ETFs

Cryptocurrency News: New Exchanges Could Boost Crypto Liquidity

Cryptocurrency News
Even though the cryptocurrency news was upbeat in recent days, the market tumbled after the U.S. Securities and Exchange Commission (SEC) rejected calls for a Bitcoin (BTC) exchange-traded fund (ETF).

That news came as a blow to investors, many of whom believe the ETF would open the cryptocurrency industry up to pension funds and other institutional investors. This would create a massive tailwind for cryptos, they say.

So it only follows that a rejection of the Bitcoin ETF should send cryptos tumbling, correct? Well, maybe you can follow that logic. To me, it seems like a dramatic overreaction.

I understand that legitimizing cryptos is important. But.

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Cryptocurrency News: New Exchanges Could Boost Crypto Liquidity

Cryptocurrency News: Bitcoin ETF Rejection, AMD Microchip Sales, and Hedge Funds

Cryptocurrency News
Although cryptocurrency prices were heating up last week (Bitcoin, especially), regulators poured cold water on the rally by rejecting calls for a Bitcoin exchange-traded fund (ETF). This is the second time that the proposal fell on deaf ears. (More on that below.)

Crypto mining ran into similar trouble, as you can see from Advanced Micro Devices, Inc.‘s (NASDAQ:AMD) most recent quarterly earnings. However, it wasn’t all bad news. Investors should, for instance, be cheering the fact that hedge funds are ramping up their involvement in cryptocurrency markets.

Without further ado, here are those stories in greater detail.
ETF Rejection.

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Cryptocurrency News: What You Need to Know This Week

Cryptocurrency News
Cryptocurrencies traded sideways since our last report on cryptos. However, I noticed something interesting when playing around with Yahoo! Finance’s cryptocurrency screener: There are profitable pockets in this market.

Incidentally, Yahoo’s screener is far superior to the one on CoinMarketCap, so if you’re looking to compare digital assets, I highly recommend it.

But let’s get back to my epiphany.

In the last month, at one point or another, most crypto assets on our favorites list saw double-digit increases. It’s true that each upswing was followed by a hard crash, but investors who rode the trend would have made a.

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Nanomedicine – Wikipedia

Nanomedicine is the medical application of nanotechnology.[1] Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials (materials whose structure is on the scale of nanometers, i.e. billionths of a meter).

Functionalities can be added to nanomaterials by interfacing them with biological molecules or structures. The size of nanomaterials is similar to that of most biological molecules and structures; therefore, nanomaterials can be useful for both in vivo and in vitro biomedical research and applications.Thus far, the integration of nanomaterials with biology has led to the development of diagnostic devices, contrast agents, analytical tools, physical therapy applications, and drug delivery vehicles.

Nanomedicine seeks to deliver a valuable set of research tools and clinically useful devices in the near future.[2][3] The National Nanotechnology Initiative expects new commercial applications in the pharmaceutical industry that may include advanced drug delivery systems, new therapies, and in vivo imaging.[4] Nanomedicine research is receiving funding from the US National Institutes of Health Common Fund program, supporting four nanomedicine development centers.[5]

Nanomedicine sales reached $16 billion in 2015, with a minimum of $3.8 billion in nanotechnology R&D being invested every year. Global funding for emerging nanotechnology increased by 45% per year in recent years, with product sales exceeding $1 trillion in 2013.[6] As the nanomedicine industry continues to grow, it is expected to have a significant impact on the economy.

Nanotechnology has provided the possibility of delivering drugs to specific cells using nanoparticles.[7] The overall drug consumption and side-effects may be lowered significantly by depositing the active agent in the morbid region only and in no higher dose than needed. Targeted drug delivery is intended to reduce the side effects of drugs with concomitant decreases in consumption and treatment expenses. Drug delivery focuses on maximizing bioavailability both at specific places in the body and over a period of time. This can potentially be achieved by molecular targeting by nanoengineered devices.[8][9] A benefit of using nanoscale for medical technologies is that smaller devices are less invasive and can possibly be implanted inside the body, plus biochemical reaction times are much shorter. These devices are faster and more sensitive than typical drug delivery.[10] The efficacy of drug delivery through nanomedicine is largely based upon: a) efficient encapsulation of the drugs, b) successful delivery of drug to the targeted region of the body, and c) successful release of the drug.[citation needed]

Drug delivery systems, lipid-[11] or polymer-based nanoparticles, can be designed to improve the pharmacokinetics and biodistribution of the drug.[12][13][14] However, the pharmacokinetics and pharmacodynamics of nanomedicine is highly variable among different patients.[15] When designed to avoid the body’s defence mechanisms,[16] nanoparticles have beneficial properties that can be used to improve drug delivery. Complex drug delivery mechanisms are being developed, including the ability to get drugs through cell membranes and into cell cytoplasm. Triggered response is one way for drug molecules to be used more efficiently. Drugs are placed in the body and only activate on encountering a particular signal. For example, a drug with poor solubility will be replaced by a drug delivery system where both hydrophilic and hydrophobic environments exist, improving the solubility.[17] Drug delivery systems may also be able to prevent tissue damage through regulated drug release; reduce drug clearance rates; or lower the volume of distribution and reduce the effect on non-target tissue. However, the biodistribution of these nanoparticles is still imperfect due to the complex host’s reactions to nano- and microsized materials[16] and the difficulty in targeting specific organs in the body. Nevertheless, a lot of work is still ongoing to optimize and better understand the potential and limitations of nanoparticulate systems. While advancement of research proves that targeting and distribution can be augmented by nanoparticles, the dangers of nanotoxicity become an important next step in further understanding of their medical uses.[18]

Nanoparticles are under research for their potential to decrease antibiotic resistance or for various antimicrobial uses.[19][20][21] Nanoparticles might also used to circumvent multidrug resistance (MDR) mechanisms.[7]

Advances in lipid nanotechnology were instrumental in engineering medical nanodevices and novel drug delivery systems, as well as in developing sensing applications.[22] Another system for microRNA delivery under preliminary research is nanoparticles formed by the self-assembly of two different microRNAs deregulated in cancer.[23] One potential application is based on small electromechanical systems, such as nanoelectromechanical systems being investigated for the active release of drugs and sensors for possible cancer treatment with iron nanoparticles or gold shells.[24]

Some nanotechnology-based drugs that are commercially available or in human clinical trials include:

Existing and potential drug nanocarriers have been reviewed.[7][30][31][32][33]

Nanoparticles have high surface area to volume ratio. This allows for many functional groups to be attached to a nanoparticle, which can seek out and bind to certain tumor cells.[34] Additionally, the small size of nanoparticles (5 to 100 nanometers), allows them to preferentially accumulate at tumor sites (because tumors lack an effective lymphatic drainage system). Limitations to conventional cancer chemotherapy include drug resistance, lack of selectivity, and lack of solubility.[35]

In vivo imaging is another area where tools and devices are being developed.[36] Using nanoparticle contrast agents, images such as ultrasound and MRI have a favorable distribution and improved contrast. In cardiovascular imaging, nanoparticles have potential to aid visualization of blood pooling, ischemia, angiogenesis, atherosclerosis, and focal areas where inflammation is present.[36]

The small size of nanoparticles endows them with properties that can be very useful in oncology, particularly in imaging.[7] Quantum dots (nanoparticles with quantum confinement properties, such as size-tunable light emission), when used in conjunction with MRI (magnetic resonance imaging), can produce exceptional images of tumor sites. Nanoparticles of cadmium selenide (quantum dots) glow when exposed to ultraviolet light. When injected, they seep into cancer tumors. The surgeon can see the glowing tumor, and use it as a guide for more accurate tumor removal.These nanoparticles are much brighter than organic dyes and only need one light source for excitation. This means that the use of fluorescent quantum dots could produce a higher contrast image and at a lower cost than today’s organic dyes used as contrast media. The downside, however, is that quantum dots are usually made of quite toxic elements, but this concern may be addressed by use of fluorescent dopants.[37]

Tracking movement can help determine how well drugs are being distributed or how substances are metabolized. It is difficult to track a small group of cells throughout the body, so scientists used to dye the cells. These dyes needed to be excited by light of a certain wavelength in order for them to light up. While different color dyes absorb different frequencies of light, there was a need for as many light sources as cells. A way around this problem is with luminescent tags. These tags are quantum dots attached to proteins that penetrate cell membranes.[37] The dots can be random in size, can be made of bio-inert material, and they demonstrate the nanoscale property that color is size-dependent. As a result, sizes are selected so that the frequency of light used to make a group of quantum dots fluoresce is an even multiple of the frequency required to make another group incandesce. Then both groups can be lit with a single light source. They have also found a way to insert nanoparticles[38] into the affected parts of the body so that those parts of the body will glow showing the tumor growth or shrinkage or also organ trouble.[39]

Nanotechnology-on-a-chip is one more dimension of lab-on-a-chip technology. Magnetic nanoparticles, bound to a suitable antibody, are used to label specific molecules, structures or microorganisms. In particular silica nanoparticles are inert from the photophysical point of view and might accumulate a large number of dye(s) within the nanoparticle shell.[40] Gold nanoparticles tagged with short segments of DNA can be used for detection of genetic sequence in a sample. Multicolor optical coding for biological assays has been achieved by embedding different-sized quantum dots into polymeric microbeads. Nanopore technology for analysis of nucleic acids converts strings of nucleotides directly into electronic signatures.[citation needed]

Sensor test chips containing thousands of nanowires, able to detect proteins and other biomarkers left behind by cancer cells, could enable the detection and diagnosis of cancer in the early stages from a few drops of a patient’s blood.[41] Nanotechnology is helping to advance the use of arthroscopes, which are pencil-sized devices that are used in surgeries with lights and cameras so surgeons can do the surgeries with smaller incisions. The smaller the incisions the faster the healing time which is better for the patients. It is also helping to find a way to make an arthroscope smaller than a strand of hair.[42]

Research on nanoelectronics-based cancer diagnostics could lead to tests that can be done in pharmacies. The results promise to be highly accurate and the product promises to be inexpensive. They could take a very small amount of blood and detect cancer anywhere in the body in about five minutes, with a sensitivity that is a thousand times better a conventional laboratory test. These devices that are built with nanowires to detect cancer proteins; each nanowire detector is primed to be sensitive to a different cancer marker.[24] The biggest advantage of the nanowire detectors is that they could test for anywhere from ten to one hundred similar medical conditions without adding cost to the testing device.[43] Nanotechnology has also helped to personalize oncology for the detection, diagnosis, and treatment of cancer. It is now able to be tailored to each individuals tumor for better performance. They have found ways that they will be able to target a specific part of the body that is being affected by cancer.[44]

Magnetic micro particles are proven research instruments for the separation of cells and proteins from complex media. The technology is available under the name Magnetic-activated cell sorting or Dynabeads among others. More recently it was shown in animal models that magnetic nanoparticles can be used for the removal of various noxious compounds including toxins, pathogens, and proteins from whole blood in an extracorporeal circuit similar to dialysis.[45][46] In contrast to dialysis, which works on the principle of the size related diffusion of solutes and ultrafiltration of fluid across a semi-permeable membrane, the purification with nanoparticles allows specific targeting of substances. Additionally larger compounds which are commonly not dialyzable can be removed.[citation needed]

The purification process is based on functionalized iron oxide or carbon coated metal nanoparticles with ferromagnetic or superparamagnetic properties.[47] Binding agents such as proteins,[46] antibodies,[45] antibiotics,[48] or synthetic ligands[49] are covalently linked to the particle surface. These binding agents are able to interact with target species forming an agglomerate. Applying an external magnetic field gradient allows exerting a force on the nanoparticles. Hence the particles can be separated from the bulk fluid, thereby cleaning it from the contaminants.[50][51]

The small size (

This approach offers new therapeutic possibilities for the treatment of systemic infections such as sepsis by directly removing the pathogen. It can also be used to selectively remove cytokines or endotoxins[48] or for the dialysis of compounds which are not accessible by traditional dialysis methods. However the technology is still in a preclinical phase and first clinical trials are not expected before 2017.[53]

Nanotechnology may be used as part of tissue engineering to help reproduce or repair or reshape damaged tissue using suitable nanomaterial-based scaffolds and growth factors. Tissue engineering if successful may replace conventional treatments like organ transplants or artificial implants. Nanoparticles such as graphene, carbon nanotubes, molybdenum disulfide and tungsten disulfide are being used as reinforcing agents to fabricate mechanically strong biodegradable polymeric nanocomposites for bone tissue engineering applications. The addition of these nanoparticles in the polymer matrix at low concentrations (~0.2 weight%) leads to significant improvements in the compressive and flexural mechanical properties of polymeric nanocomposites.[54][55] Potentially, these nanocomposites may be used as a novel, mechanically strong, light weight composite as bone implants.[citation needed]

For example, a flesh welder was demonstrated to fuse two pieces of chicken meat into a single piece using a suspension of gold-coated nanoshells activated by an infrared laser. This could be used to weld arteries during surgery.[56]Another example is nanonephrology, the use of nanomedicine on the kidney.

Neuro-electronic interfacing is a visionary goal dealing with the construction of nanodevices that will permit computers to be joined and linked to the nervous system. This idea requires the building of a molecular structure that will permit control and detection of nerve impulses by an external computer. A refuelable strategy implies energy is refilled continuously or periodically with external sonic, chemical, tethered, magnetic, or biological electrical sources, while a nonrefuelable strategy implies that all power is drawn from internal energy storage which would stop when all energy is drained. A nanoscale enzymatic biofuel cell for self-powered nanodevices have been developed that uses glucose from biofluids including human blood and watermelons.[57] One limitation to this innovation is the fact that electrical interference or leakage or overheating from power consumption is possible. The wiring of the structure is extremely difficult because they must be positioned precisely in the nervous system. The structures that will provide the interface must also be compatible with the body’s immune system.[58]

Molecular nanotechnology is a speculative subfield of nanotechnology regarding the possibility of engineering molecular assemblers, machines which could re-order matter at a molecular or atomic scale. Nanomedicine would make use of these nanorobots, introduced into the body, to repair or detect damages and infections. Molecular nanotechnology is highly theoretical, seeking to anticipate what inventions nanotechnology might yield and to propose an agenda for future inquiry. The proposed elements of molecular nanotechnology, such as molecular assemblers and nanorobots are far beyond current capabilities.[1][58][59][60] Future advances in nanomedicine could give rise to life extension through the repair of many processes thought to be responsible for aging. K. Eric Drexler, one of the founders of nanotechnology, postulated cell repair machines, including ones operating within cells and utilizing as yet hypothetical molecular machines, in his 1986 book Engines of Creation, with the first technical discussion of medical nanorobots by Robert Freitas appearing in 1999.[1] Raymond Kurzweil, a futurist and transhumanist, stated in his book The Singularity Is Near that he believes that advanced medical nanorobotics could completely remedy the effects of aging by 2030.[61] According to Richard Feynman, it was his former graduate student and collaborator Albert Hibbs who originally suggested to him (circa 1959) the idea of a medical use for Feynman’s theoretical micromachines (see nanotechnology). Hibbs suggested that certain repair machines might one day be reduced in size to the point that it would, in theory, be possible to (as Feynman put it) “swallow the doctor”. The idea was incorporated into Feynman’s 1959 essay There’s Plenty of Room at the Bottom.[62]

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Nanomedicine – Wikipedia

Nanomedicine Conferences | Nanotechnology Events …

About Conference

ME Conferences invites all the participants from all over the world to attendNanomedicine and Nanotechnology in Health CareDuring 17-19 September, 2018 at Abu Dhabi, UAE. This includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions. And it provides an opportunity to learn about the complexity of the Diseases, discuss interventional procedures, look at new and advances in Nanotechnology and their efficiency and efficacy in diagnosing and treating various diseases and also in Healthcare treatments.

ME Conferences organizes 1000+ Global Events Every Year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open access journals which contains over 1,00,000 eminent personalities, reputed scientists as editorial board and organizing committee members. ME Conferences journals have over 5 million readers and the fame and success of the same can be attributed to the strong editorial board which contains over 30000 eminent personalities and the rapid, quality and quick review processing.ME Conferences make the perfect platform for global networking as it brings together renowned speakers and scientists across the globe to a most exciting and memorable scientific event filled with much enlightening interactive sessions, international workshops, world class international exhibitions and poster presentations.

Why to attend?

This Conference Nanomedicinemeet 2018 will focus on Healthcare and Medicine. World-renowned speakers, the most recent techniques, tactics, and the newest updates in fields Nanotechnology and Engineering, Medical Nanotechnology, Tissue Engineering are hallmarks of this conference. Nanomedicinemeet-2018 is an exciting opportunity to showcase the modern technology, the new products of your company, and/or the service your industry may offer to a broad international audience. It covers a lot of topics and it will be a nice platform to showcase their recent researches on Nanotechnology, MaterialScienceand other interesting topics.

Target Audience:

The termNano medicineencompasses a broad range of technologies and materials. Types of nanomaterials that have been investigated for use as drugs,, drug carriersor other Nonmedical agents. There has been steep growth in development of devices that integrate nanomaterials or other nanotechnology. Thenanotechnology-based medical devices market is categorized into three major segments, namely, therapeutic applications, diagnostics applications, and research applications. Rising incidence of lifestyle and age-related disorders (such as cardiovascular and hearing disorders) has contributed significantly to the growth of the nanotechnology-based active implantable devices market. Nanotechnology, or systems/device manufacture at the molecular level, is a multidisciplinary scientific field undergoing explosive development. The genesis of nanotechnology can be traced to the promise of revolutionary advances across medicine, communications and genomics. On the surface, miniaturization provides cost effective and more rapidlyfunctioningbiological components. Less obvious though is the fact that Nanometer sized objects also possess remarkableself-ordering and assemblybehaviors under the control of forces quite different from macro objects.

Advances in technology have increased our ability to manipulate the world around us . Nanotechnology is rapidly emerging within the realm of medicine. Nanomedicine is the process of diagnosing, treating, and preventing disease andtraumatic injury, of relieving pain, and of preserving and improving human health, using molecular tools and molecular knowledge of the human body. An exciting and promising area of Nano technological development is the building of Nanorobots. Highly precise positioning techniques are required in Miniaturing in chip technology, optics , micro mechanic, medicine , gene and biotechnology. The new manipulation technology is the desire to enter the micro and Nano world not only by viewing but also acting, alteringmicro andNanosized objects. Nanorobots plays a critical roles for many applications in the human body, such astargetingtumoral lesionsfor therapeutic purposes, miniaturization of the power source with an effective onboard controllable propulsion and steering system have prevented the implementation of such mobile robots.

The therapeutic properties of light have been known for thousands of years, but it was only in the last century that photodynamic therapy (PDT) was developed. It is an emerging modality for the treatment of a variety of diseases that require the killing of pathological cells (e.g. cancer cells or infectious micro-organisms) or the removal of unwanted tissue (e.g. neovascularization in the choroid or atherosclerotic plaques in the arteries). It is based on the excitation of nontoxic photosensitizers.Photodynamic therapy(PDT) uses the combination of dyes with visible light to produce reactive oxygen species and kill bacteria and destroy unwanted tissue. Nanotechnology plays a great role insolubilizing thephotosensitizers, metal nanoparticles can carry out Plasmon resonance enhancement, andfullerenescan act as photosensitizers, themselves.

Nanotechnology is becoming increasingly important for the several sectors. Promising results and applications are already being developed in the areas of nutrient delivery systems through bioactive Nano encapsulation,biosensorsto detect and quantifypathogens organic compounds. The sensitivity and performance of biosensors is being improved by using nanomaterials for their construction. The use of these nanomaterials has allowed the introduction of many new signal transduction technologies in biosensors. Many scientists have involved themselves to know the application and the benefits of nanotechnology in different areas of food industry that include bioactive Nano encapsulation, edible thin film, packages andNano sensors.

Green chemistry and Nano science are both emerging fields that take advantage of molecular-level designing and have enormous potential for advancing our science. Nano science is the study of materials that are on the length-scale of 100 nanometers or smaller and have properties that are dependent on their physical size. The principles of green chemistry can guide responsible development of Nano science, while the new strategies of Nano science can fuel the development ofgreener productsand processes.Phytochemicalsoccluded in tea have been extensively used as dietary supplements and as naturalpharmaceuticalsin the treatment The parallel development of green chemistry and Nano science and the potential synergy of the two fields can lead to more successful and profitable technologies with reduced environmental impacts and improved conservation of resources. In recent years, green synthesis ofmetal nanoparticlesis an interesting issue of the nanoscience.

Nanotechnologyis enabling technology that deals with Nano-meter sized objects. It is expected that nanotechnology will be developed at several levels: materials, devices and systems. The combination of biology and nanotechnology has led to a new generation ofNano devicesthat opens the possibility to characterize the chemical, physical, mechanical, and other molecular properties. And it can be even used to characterize the single molecules or cells at extraordinarily high throughput.Nanoparticleswith distinctive chemical compositions, sizes, shapes, and surface chemistries can be engineered easily and this technique has wide range of applications in biological systems.Utility of nanotechnology to biomedical sciences imply creation of materials and devices designed tointeraction in sub-cellular scaleswith a high degree of specificity.

Biopolymer nanoparticles are offering numerous advantages which embrace the simplicity of their preparation from well-understood biodegradable, biocompatible polymers and their high stability inbiological fluidsduring storage. Since the emergence of Nanotechnology in the past decades, the development and design of organic andbioorganic nanomaterialshas become an important field of research. And several types of polymers have been tested and are used in drug delivery systems; including nanoparticles, dendrimers, capsosomes and micelles. Researchers have found, the synthesized polymers even serves as a good carrier and plays a vital role in carrying a drug. And in other hand they are used in food industries too for food package purposes. There are thousands of organic chemicals are in present in various pharmaceutical to consumer product and are being used in dyes, flavoring agents. It can be explained in organic compounds ranging in diameter from 10 to 1m.Ultrafine particlesare the same asnanoparticlesand between 1 and 100 nanometers in size, fine particles are sized between 100 and 2,500 nanometers, and coarse particles cover a range between 2,500 and 10,000nanometers.

The biological synthesis ofnanoparticlesis synthesis method through which we can control, size and shape of nanoparticles and it increasingly regarded as a rapid, ecofriendly, and easily scaled-up technology. Over the past few years researches have shown their interest inmetallic nanoparticlesand their synthesis has greatly increased. However, drawbacks such as the involvement oftoxic chemicalsand the high-energy requirements of production. Synthesizing living organisms such as bacteria, fungi and plants is an alternative way to overcome the drawbacks. Plant mediated synthesis of nanoparticles is the green chemistry that connects. Generally, metal nanoparticles are synthesized and stabilized by using physical and chemical: the chemical approach, such as chemical reduction,electrochemical techniques,photochemical reactionsin reverse micelles. There is a growing attention to biosynthesis the metal nanoparticles using organisms. Among these organisms, plants seem to be the best candidate and they are suitable for large scale biosynthesis of nanoparticles.

Nanoparticles used asdrug deliveryvehicles are generally below 100 nm , and are coated with different biodegradable materials such as natural or synthetic polymers (PEG,PVA,PLGA,etc.), lipids, or metals , it plays significant role on cancer treatment as well as it holds tremendous potential as an effective drug delivery system. A targeted drug delivery system (TDDS) is a system, which releases the drug in a controlled manner. Nanosystems with different compositions and biological properties have been extensively investigated for drug and gene delivery applications. To achieve efficient drug delivery it is important to understand the interactions ofNanomaterialswith the biological environment, targetingcell-surface receptors, drug release, multiple drug administration, stability of therapeutic agents. Nanotechnology refers to structures roughly in the 1100 nm size regime in at least one dimension. Despite this size restriction, nanotechnology commonly refers to structures that are up to several hundred nanometers in size and that are developed bytop-down or bottom-up engineering of individual components.

Nanosuspention formulation can be used to improve the solubility of the poorly soluble drugs. One of the major problems associated with poorly soluble drugs is very low bioavailability. The Preparation ofNanosuspentionis simple and applicable to all drugs which are water insoluble. It consists of the pure poorly water-soluble drug without any matrix material suspended in dispersion . Various techniques are used for the enhancement of the solubility of poorly soluble drugs which include physical and chemical modifications of drug and other methods like particle size reduction,crystal engineering, salt formation, solid dispersion, use ofsurfactant, complexation A range of parameters like solubility, stability at room temperature, compatibility with solvent, excipient, andphotostabilityplay a critical role in the successful formulation of drugs. Use of some drug which is potentially restricted because of its toxic side-effects and its poor solubility, making it unsuitable for intravenous use in patients withdrug malabsorption.

Nano medicine drives the convergence of nanotechnology and medicine it is delineated as the application of nanotechnology in healthcare. The field of tissue engineering has developed in phases: initially researchers searched for inert biomaterialsto act solely as replacement structures in the body. Tissue engineering is classified as an associate field of biomaterialsand engineering. It focuses on the use of cellular and material-based therapies aimed attargeted tissue regenerationcaused by traumatic, degenerative, and genetic disorders.It covers a broad range of applications, in practice the term has come to represent applications that repair or replace structural tissues (i.e., bone, cartilage, blood vessels, bladder, etc.). Today, these Nano scale technologies are coming to the forefront in medicine because of their biocompatibility, tissue-specificity, and integration and ability to act as therapeutic carriers.

Polymeric nanoparticles (NPs) are one of the most studied organic strategies for Nano medicine. Intense interest lies in the potential ofpolymeric NPsto revolutionize modern medicine. Polymeric NPs include drug delivery techniques such as conjugation and entrapment of drugs,prodrugs, stimuli-responsive systems,imaging modalities, and theranostics.The use of biodegradable polymeric nanoparticles (NPs) for controlled drug delivery has shown significanttherapeutic potential. Concurrently, targeted delivery technologies are becoming increasingly important as a scientific area of investigation. Polymericnanoparticles-based therapeutics show great promise in the treatment of a wide range of diseases, due to the flexibility in which their structures can be modified, with intricate definition over their compositions, structures and properties. Advances in polymerizationchemistries and the application of reactive, efficient andorthogonal chemicalmodification reactionshave enabled the engineering of multifunctional polymericnanoparticles.

In recent years,microbubbleand Nano bubble technologies have drawn great attention due to their wide applications in many fields of science and technology, such as water treatment,biomedical engineering, and nanomaterials.Nano bubblesexhibit unique characteristics; due to their minute size and high internal pressure, they can remain stable in water for prolonged periods of time. Nanobubbles can be created whengold nanoparticlesare struck by short laser pulses. The short-lived bubbles are very bright and can be made smaller or larger by varying the power of the laser. Because they are visible under a microscope, nanobubbles can be used to either diagnose sick cells or to track the explosions that are destroying them.

Natural productshave been used in medicine for many years. Many top-sellingpharmaceuticalsare natural compounds or their derivatives.. And plant- or microorganism-derived compounds have shown potential as therapeutic agents against cancer, microbial infection, inflammation, and other disease conditions. Natural products had huge success in the post-World War II era as antibiotics, and the two terms have become synonymous.While large pharmaceutical companies have favored screening synthetic compound libraries for drug discovery, small companies have started to explore natural products uses against cancer, microbial infection, inflammation, and other diseases.The incorporation of nanoparticles into a delivery system for natural products would be a major advance in the efforts to increase their therapeutic effects. Recently, advances have been made showing that nanoparticles can significantly increase the bioavailability of natural products bothin vitro and in vivo.

Nanoscience and nanotechnology are new frontiers of this century and food nanotechnology is an emerging technology. Food technology is regarded as one of the industry sectors where nanotechnology will play an important role in the future. The development of new products and applications involving nanotechnologies holds great promise in different industrial sectors, Nanotechnology may revolutionize the food industry by providing stronger, high-barrier packaging materials, more potentantimicrobial agents. Several possibilities exist to exploit the benefits of nanotechnologies during different phases of the food chain with the aim to enhance animal nutrition and health. Several complex set of engineering and scientific challenges in the food and bioprocessing industries for manufacturing high quality and safe food through efficient and sustainable means can be solved through nanotechnology. Bacteria identification and food quality monitoring using biosensors; intelligent, active, and smart food packaging systems; and Nanoencapsulationofbioactive food compoundsare few examples of emerging applications of nanotechnology for the food industry.

The main current applications of Nanotechnology for surgeons are in the areas of development of surgical implants using Nanomaterials, Imaging, Drug Delivery and development of Tissue Engineering products, such as scaffolds with enhanced materialcell interaction. An example of this is the development of a scaffold for delivery of stem cells to replace defective retinal pigmented epithelial cells in age-related Macular Degeneration. In Dentistry research has been done, liposomal Nanoparticles that contained collagenase and performed tests with them in rats, and found compared to conventional surgery, collagenase weakened the collagen fibers, making it easier to shift the teeth afterward with braces.

Nanoparticles with their unique size-dependent properties are at the forefront of advanced material engineering applications in several fields. Metals, non-metals, bio-ceramics, and manypolymeric materialsare used to produce nanoparticles of the respective materials. These are functional in producing liposomes, PEG and many more. Due to their small size nanoparticles has found to be interacting with human bodies same like of gases. Nanoparticles of the same composition can display behavioral differences when interacting with different environments. Nanoparticles can enter the human body via inhalation, ingestion, or skin contact. The range of pathologiesrelated to exposure tonanoparticles encompasses respiratoryand even several organs and leads to diseases. Accurate in vitro assessment ofnanoparticle cytotoxicityrequires a careful selection of the test systems. Due to high adsorption capacity and optical activity, engineered nanoparticles are highly potential in influencing classical cytotoxicity assays.

One of the exciting features of nanotechnology is its utility in the field of Nano medicine, therapeutics, and medical devices . When these small size materials are introduced into biological systems, their extremely small size and their unique Nano scale properties make it possible to use them as delivery vectors and probes for biological diagnostics,bioimagingand therapeutics. In fact, when size decreases, thesurface area to volume ratioof materials becomes very large, so that a vast suitable surface is available forchemical interactions withbiomolecules. This critically implied that nanotechnology is facing a transition into the tangible advancement ofhuman therapeutics. Recently, There are multiple clinical trials of nanomaterials have done; both for therapeutics and for medical devices.

Related conferences: Nanomedicine Conferences | Nanotechnology Events | Nano Healthcare Congress | Nanomedicine Meet | Nanoscience Event | Nanoengineering Conference | Tissue Engineering Meeting

Related Societies:

USA:International Organization of Materials, International Association of Nanotechnology, Graphene Stakeholders Association, Nano Science and Technology Institute (NSTI),NanoBusiness Commercialization Association, Alliance for Nanotechnology in Cancer,International association of nanotechnology,National Institute for Nanotechnology, Waterloo Institute for Nanotechnology, The Institute for Molecular Manufacturing (IMM),NanoBusiness Alliance, Nanotechnology and Nanoscience Student Association (NANSA),Nano Science and Technology Institute (NSTI),National Cancer Institute, National Nanotechnology Initiative,American Nano society, Metals and Minerals Societies, Society for Advancement of Material and process Engineering,American Composites Manufacturers Association, Brazilian Composites Materials Association,Canadian Biomaterials Society, American Institute of Aeronautics and Astronautics (AIAA).

Europe:International Union of Crystallography, European Nanoscience and Nanotechnology Association (ENNA),German Association of Nanotechnology, Nanotechnology Industries Association, The Institute of Nanotechnology (IoN), Nanotechnology Industries Association (NIA),Russian Society of Scanning Probe Microscopy and Nanotechnology, Society of Nanoscience and Nanotechnology, Federation of Materials Societies, Society for Biomaterials, Federation of European Materials Societies

Asia-Pacific & Middle East:Nano Technology Research Association (NTRA), Asian Nanoscience and Nanotechnology Association (ANNA), Nanoscience & Nanotechnology, ASPEN-Asian society of precision engineering and nanotechology, The International Association of Nanotechnology (IANT), Iran Nanotechnology Initiative Council (INIC), National Institutes of Health, Society of Materials Science, Japan Society for Composite Materials, Australasian Society for Biomaterials and Tissue Engineering, Australasian Ceramic Society, Materials Research Society, National Centre for Nanoscience and Technology.

Theme: Role of Nanotechnology in Humans life

Summary:

The field of Nanotechnology has recently emerged as the most commercially viable technology of this century because of its wide-ranging applications in our daily lives. Man-made Nanostructured materials such as fullerenes, nanoparticles, Nano powders, Nanotubes, Nanowires, Nanorods, Nano-fibers, Quantum dots, Dendrimers, Nano clusters, Nanocrystals, and Nanocomposites are globally produced in large quantities due to their wide potential applications, e.g., in skincare and consumer products, healthcare, electronics, photonics, biotechnology, engineering products, Pharmaceuticals, drug delivery, and agriculture. Many emerging economies such as Brazil, China, India, Iran, UAE, Malaysia, Mexico, Singapore and South Africa have ambitious research and development (R&D) plans for Nanotechnology.A group of scientists who have mapped out the uses of Nanotechnology and the needs of global health argue that Nano medicine is relevant for the developing world. They surveyed researchers worldwide and concluded that Nanotechnology could greatly contribute to meeting the Millennium Development Goals for health.

Importance and scope:

Nanotechnologyis becoming a crucial driving force behind innovation in medicine and healthcare, with a range of advances including Nano scale therapeutics, biosensors, implantable devices, drug delivery systems, and imaging technologies. Universities also have begun to offer dedicated Nano medicine degree programs (example:MSc program in Nanotechnology for Medicine and Health Care). Nanotechnology will be getting to be progressively prevalent these times Around learners. Actually, if you follow again of the Inception about nanotechnology, you will discover that Ayurveda need long been utilizing gold Also silver nanoparticles, known as bhasmas, to treat Different therapeutic ailments. Presently, nanotechnology may be generally utilized within huge numbers industries, going from cosmetics, agriculture, and materials should pharmaceutical Also human services. Nanomedicine may be the provision for nanotechnology for those diagnoses, detection, and medicine Also aversion of illnesses. Presently there need aid various items on the business that would the outcome from claiming nanotechnology. Talking for scratching the surface, we likewise have Nano auto wax that fills done the individuals minor cracks more successfully Furthermore provides for you a shinier vehicle. There need aid likewise Nano items accessible with stay with your eyewear What’s more different optical units cleaner, dryer, What’s more that’s only the tip of the iceberg tough.

Conference highlights:

Why in Abu Dhabi?

Abu Dhabi is the federal capital and centre of government in the United Arab Emirates sits off the mainland on an island in the Persian (Arabian) Gulf. It is the largest city of the Emirate of Abu Dhabi and one of the most modern cities in the world. It is a well-ordered, industrious city with a pretty waterside location. Innovative Nano Technology LLC was founded in the beginning of 2016 in Al Ain City, Abu Dhabi, United Arab Emirates. It was established with the goal of taking a leading role in the field of Nano Technology Based Coatings, and is considered as one of the first Companies who offer the new Nano technology based Coatings in the region.

Why to attend?

United Arab Emirates has a number of universities that offer research and educational opportunities in nanotechnology. United Arab Emirates University, The first and foremost comprehensive National University in the United Arab Emirates. eFORS office is the University consultancy office within the college of engineering that deals with several science and technology issues including Biochemical and Biopharmaceutical Processes and Bioengineering and Nanotechnology. Reports released during October 2012 revealed that the worlds second largest foundry, Globalfoundries has agreed to partner with Masdar Institute to develop Abu Dhabi as a centre for semiconductor R&D and manufacturing excellence. In September, the company allowed students and professors to use its technology facilities at its Abu Dhabi branch. The facilities have a laboratory-like environment with powerful production servers, engineering work stations and a high-speed data network that can be used for enabling remote access to very advanced nanotechnology engineering systems

Technology domains of patent applications in UAE

This graph shows the global Nanomedicine market size, measured in terms of revenues, such as sales revenues, grants revenues, and milestones. From2006to date, a steady growth has occurred, which is expected to continue through2014, at aCAGRof13.5% [BCCResearch, Nanotechnology in Medical Applications. The drug delivery market is the largest contributing application segment, whereas biomaterials are the fastest growing application area in this market. Nanomedicine accounts for77Marketed Products Worldwide, representing an Industry with an estimated market $249.9Billion by2016[ETPNdata,BCC].

Globally, the industry players would centering essentially once R&D to get Regard for Different clinical trials for future Nanodrugs with a chance to be economically accessible in the business sector. If a chance to be generally arranged for exactly of the most punctual What’s more The greater part essential requisitions of Nano medicine for regions for example, gene treatment and tissue building. The a greater amount propelled requisitions for Nano medicine will pose interesting tests As far as order Furthermore support about exploratory dexterity.

Nano medicine market :

Nano-enabled medical products beganappearing on the market over a decade ago and some have become best-sellers in theirtherapeutic categories. The main areas in which Nanomedical products have made animpact are cancer, CNS diseases, cardiovascular disease, and infection control. At present, cancer is one of the largesttherapeutic areas in which Nano-enabled products have made major contributions; theseinclude Abraxane, Depocyt, Oncospar, Doxil,and Neulasta. Cancer is a prime focus forNano pharmaceutical R&D, and companieswith clinical-stage developments in this fieldinclude Celgene, Access, Camurus, andCytimmune. Treatments for CNS disorders includingAlzheimers disease and stroke also feature prominently in Nano therapeutic research,seeking to build on achievements already posted by products such as Tysabri, Copazone,and Diprivan. According to BCC Research,this is a field hungry for successfultherapeutic advances and annual growth fromexisting and advanced pipeline products isexpected to reach 16% over the next 5 years.

Nanotechnology Companies in Asia and Middle East:

Nano Congress 2017

We gratefully thank all our wonderful Speakers, Conference Attendees, Students, Media Partners, Associations and Sponsors for making Nano Congress 2017 Conference the best ever!

The19thNano Congress for Next Generation, hosted by the ME Conferences was held duringAugust 31- September 01, 2017atBrussels, Belgiumbased on the themeNext Generation Nanotechnology Concepts Methodologies Tools and Applications”. Benevolent response and active participation was received from the Organizing Committee Members along with Scientists, Researchers, Students and leaders from various fields of Nanotechnology who made this event a grand success.

ME Conferences expresses its gratitude to the conference Moderator,namelyDr.Dominique Ausserrefor taking up the responsibility to coordinate during the sessions. We are indebted to your support.

Similarly we also extend our appreciation towards our Poster judge namely,Dr. Arturs Medvids.

The conference was initiated with theHonorable presenceof theKeynote forum. The list includes:

The meeting reflected various sessions, in which discussions were held on the following major scientific tracks:

Nano Materials Synthesis and Characterisation

Nano Photonics

Molecular Nanotechnology

Nanotechnology and Cosmetics

Nanotechnology in Agriculture and Food Industry

Carbon Based Nano materials and Devices

Nanotechnology Safety

Nano Medicine and Nano Biotechnology

Nano Science and Technology

Nano Applications

Nano-electronics

Nano Biomaterials

Nano Biometric

Advanced Nanomaterials

Nano Technology in Tissue Engineering

Nanotech for Energy and Environment

Nano Computational Modelling

ME Conferences offers its heartfelt appreciation to organizations such asAllied Academies,Andrew John Publishing Inc.,New York private Equity Forum,Crowd Reviewsand other eminent personalities who supported the conference by promoting in various modes online and offline which helped the conference reach every nook and corner of the globe. ME Conferences also took privilege to felicitate the Keynote Speakers, Organizing Committee Members, Chairs and sponsors who supported this event

Excerpt from:

Nanomedicine Conferences | Nanotechnology Events …

Nanomedicine – Official Site

The mission of Nanomedicine: Nanotechnology, Biology, and Medicine (Nanomedicine: NBM) is to promote the emerging interdisciplinary field of nanomedicine.

Nanomedicine: NBM is an international, peer-reviewed journal presenting novel, significant, and interdisciplinary theoretical and experimental results…

The mission of Nanomedicine: Nanotechnology, Biology, and Medicine (Nanomedicine: NBM) is to promote the emerging interdisciplinary field of nanomedicine.

Nanomedicine: NBM is an international, peer-reviewed journal presenting novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in the life sciences. Content includes basic, translational, and clinical research addressing diagnosis, treatment, monitoring, prediction, and prevention of diseases.

The potential scope of nanomedicine is broad, and we expect it to eventually involve all aspects of medicine. Sub-categories include synthesis, bioavailability, and biodistribution of nanomedicines; delivery, pharmacodynamics, and pharmacokinetics of nanomedicines; imaging; diagnostics; improved therapeutics; innovative biomaterials; interactions of nanomaterials with cells, tissues, and living organisms; regenerative medicine; public health; toxicology; point of care monitoring; nutrition; nanomedical devices; prosthetics; biomimetics; and bioinformatics.

Article formats include Communications, Original Articles, Reviews, Perspectives, Technical and Commercialization Notes, and Letters to the Editor. We invite authors to submit original manuscripts in these categories.

Excerpt from:

Nanomedicine – Official Site

Nanomedicine Fact Sheet – National Human Genome Research …

NanomedicineOverview

What if doctors had tiny tools that could search out and destroy the very first cancer cells of a tumor developing in the body? What if a cell’s broken part could be removed and replaced with a functioning miniature biological machine? Or what if molecule-sized pumps could be implanted in sick people to deliver life-saving medicines precisely where they are needed? These scenarios may sound unbelievable, but they are the ultimate goals of nanomedicine, a cutting-edge area of biomedical research that seeks to use nanotechnology tools to improve human health.

Top of page

A lot of things are small in today’s high-tech world of biomedical tools and therapies. But when it comes to nanomedicine, researchers are talking very, very small. A nanometer is one-billionth of a meter, too small even to be seen with a conventional lab microscope.

Top of page

Nanotechnology is the broad scientific field that encompasses nanomedicine. It involves the creation and use of materials and devices at the level of molecules and atoms, which are the parts of matter that combine to make molecules. Non-medical applications of nanotechnology now under development include tiny semiconductor chips made out of strings of single molecules and miniature computers made out of DNA, the material of our genes. Federally supported research in this area, conducted under the rubric of the National Nanotechnology Initiative, is ongoing with coordinated support from several agencies.

Top of page

For hundreds of years, microscopes have offered scientists a window inside cells. Researchers have used ever more powerful visualization tools to extensively categorize the parts and sub-parts of cells in vivid detail. Yet, what scientists have not been able to do is to exhaustively inventory cells, cell parts, and molecules within cell parts to answer questions such as, “How many?” “How big?” and “How fast?” Obtaining thorough, reliable measures of quantity is the vital first step of nanomedicine.

As part of the National Institutes of Health (NIH) Common Fund [nihroadmap.nih.gov], the NIH [nih.gov] has established a handful of nanomedicine centers. These centers are staffed by a highly interdisciplinary scientific crew, including biologists, physicians, mathematicians, engineers and computer scientists. Research conducted over the first few years was spent gathering extensive information about how molecular machines are built.

Once researchers had catalogued the interactions between and within molecules, they turned toward using that information to manipulate those molecular machines to treat specific diseases. For example, one center is trying to return at least limited vision to people who have lost their sight. Others are trying to develop treatments for severe neurological disorders, cancer, and a serious blood disorder.

The availability of innovative, body-friendly nanotools that depend on precise knowledge of how the body’s molecular machines work, will help scientists figure out how to build synthetic biological and biochemical devices that can help the cells in our bodies work the way they were meant to, returning the body to a healthier state.

Top of page

Last Updated: January 22, 2014

See the article here:

Nanomedicine Fact Sheet – National Human Genome Research …

Nanomedicine

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Nanomedicine

Nanomedicinelab

2D Materials, 2018, 5: 035020

Journal of Controlled Release, 2018, 276: 157-167

ACS Nano, 2018, 12(2): 1373-1389

2D Materials, 2018, 5: 035014

Chem, 2018, 4(2): 334358

Nanoscale, 2018, 10:1180-1188

Advanced Healthcare Materials, 2017, 7 (4): 1700815

Science Robotics, 2017, 2, 12, eaaq1155

Nanoscale, 2018, 10, 12561264

In Vivo Reprogramming in Regenerative Medicine (Springer Publishing) 21st Nov. 2017, pp: 65-82

See the rest here:

Nanomedicinelab

Nanomedicinelab

2D Materials, 2018, 5: 035020

Journal of Controlled Release, 2018, 276: 157-167

ACS Nano, 2018, 12(2): 1373-1389

2D Materials, 2018, 5: 035014

Chem, 2018, 4(2): 334358

Nanoscale, 2018, 10:1180-1188

Advanced Healthcare Materials, 2017, 7 (4): 1700815

Science Robotics, 2017, 2, 12, eaaq1155

Nanoscale, 2018, 10, 12561264

In Vivo Reprogramming in Regenerative Medicine (Springer Publishing) 21st Nov. 2017, pp: 65-82

View post:

Nanomedicinelab


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