Successful results of a University of Liverpool-led trial that utilized nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, a leading annual conference of HIV research, clinical practice and progress.

The healthy volunteer trial, conducted by the collaborative nanomedicine research program led by pharmacologist Andrew Owen and materials chemist Steve Rannard, and in collaboration with the St Stephen's AIDS Trust at the Chelsea & Westminster Hospital in London, examined the use of nanotechnology to improve the delivery of drugs to HIV patients. The results were from two trials which are the first to use orally dosed nanomedicine to enable HIV therapy optimization.

Nanotechnology is the manipulation of matter on an atomic, molecular, and supramolecular scale. Nanomedicine is the application of nanotechnology to the prevention and treatment of disease in the human body. By developing smaller pills that are better for patients and less expensive to manufacture, this evolving discipline has the potential to dramatically change medical science and is already having an impact in a number of clinically used therapies and diagnostics worldwide.

Currently, the treatment of HIV requires daily oral dosing of HIV drugs, and chronic oral dosing has significant complications that arise from the high pill burden experienced by many patients across populations with varying conditions leading to non-adherence to therapies.

Recent evaluation of HIV patient groups have shown a willingness to switch to nanomedicine alternatives if benefits can be shown. Research efforts by the Liverpool team have focused on the development of new oral therapies, using Solid Drug Nanoparticle (SDN) technology which can improve drug absorption into the body, reducing both the dose and the cost per dose and enabling existing healthcare budgets to treat more patients.

The trial results confirmed the potential for a 50 percent dose reduction while maintaining therapeutic exposure, using a novel approach to formulation of two drugs: efavirenz (EFV) and, lopinavir (LPV). EFV is the current WHO-recommended preferred regimen, with 70% of adult patients on first-line taking an EFV-based HIV treatment regimen in low- and middle-income countries.

The trial is connected to the University's ongoing work as part of the multinational consortium OPTIMIZE, a global partnership working to accelerate access to simpler, safer and more affordable HIV treatment. Funded by the U.S. Agency for International Development, OPTIMIZE is led by the Wits Reproductive Health & HIV Institute in Johannesburg, South Africa, and includes the interdisciplinary Liverpool team, Columbia University, Mylan Laboratories and the Medicines Patent Pool (MPP). OPTIMIZE is supported by key partners including UNITAID and the South African Medical Research Council (SAMRC)

Benny Kottiri, USAID's Office of HIV/AIDS Research Division Chief, said: "The potential applications for HIV treatment are incredibly promising. By aligning efforts, these integrated investments offer the potential to reduce the doses required to control the HIV virus even further, resulting in real benefits globally. This would enable the costs of therapy to be reduced which is particularly beneficial for resource-limited countries where the burden of disease is highest."

Source: University of Liverpool

More here:

New Nano Approach Could Cut Dose of Leading HIV Treatment in Half - Infection Control Today

New nano approach could cut dose of leading HIV treatment in half Science Daily The healthy volunteer trial, conducted by the collaborative nanomedicine research programme led by Pharmacologist Professor Andrew Owen and Materials Chemist Professor Steve Rannard, and in collaboration with the St Stephen's AIDS Trust at the ... and more »

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New nano approach could cut dose of leading HIV treatment in half - Science Daily

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An explosion of nanotechnology research and development is occurring as newly identified forms of carbon, including graphene, carbon nanotubes and nano-diamonds, pave the way for new products and industries.

Innovations are snowballing in fields as diverse as medicine to clean energy.

Using ever more technology to manipulate and control structures at the nanoscale, scientists and engineers around the world are also looking to develop more effective medicines, longer lasting batteries for our mobile devices (including cars) and greener energy generation as well as many other applications that will benefit from big advances in small things.

We are on the cusp of nanotechnology being useful and used right across the economy and its very exciting.

Once considered science fiction, nanotech now plays a big part in our everyday life, from the materials used in computer chips and increasingly compact electronics to your phone display and the comfortable soles of running shoes.

Well before scientists understood what an atom was let alone a nanoparticle, Venetian artisans were working at nano-particle scale about 1500 years ago by treating gold in glass to generate unique visual effects.

The discipline of nanotechnology took off in the mid-1990s when the ability to see or more correctly image surfaces and particles in the range of 1-100nm (about 1/10,000 the width of a human hair) became possible.

From a practical point of view, nanotechnology is all about the way molecules arrange with each other to form a higher order structure in much the same way as bricks and glass can be organised to make a house.

We can do this by design, where we use advanced lithography to make computer chips, or we can start to design the molecules or sub-structures so that they can organise themselves.

We can also leverage the observation that the properties of materials can also change when particles become very small.

A very visible example is the transparent sunscreens that we use on a regular basis. Gone are the days when the most effective sunscreen, zinc cream, was white (or vividly coloured as it became).

Zinc oxide has the inherent ability to absorb dangerous ultraviolet light but if the particles are large, they also scatter visible light, making it appear white.By making the particles smaller, they no longer scatter light and become transparent to the human eye in a relatively simple optical trick.

In another example, gold is normally considered to be a very stable, inert material but very small gold particles have interesting catalytic properties and may lead to an economic route to split water into hydrogen and oxygen.

In addition, like many small metal and semiconducting materials, gold also changes colour to red and blue when they are very small, rather than their more familiar gold colour, which can make provide interesting optical effects from security printing to the detection of fingerprints on difficult surfaces.

Professor David Lewis leads the Centre for NanoScale Science and Technology (CNST) at Flinders where researchers work with industry under the State Government assisted NanoConnect program.

NanoConnect aims to help companies understand how the best materials and nanotechnology can help them in their processes.

The CNST, and other nanotech experts such as Professor Amanda Ellis, are leading research efforts in a number of nano fields, including making DNA nanostructures for a range of applications from bio-sensing to genotyping as well as integrating piezoelectric (energy harvesting) polymers into carbon-based energy storage devices.

Synthetic and biomaterial based polymer membranes incorporating nanotech advances are also being developed for uses such as water and gas purification.

Read more about nanotechnology and other research at Flinders in the Universitys 50th anniversary publication, The Investigator Transformed.

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Nano-size revolution is getting bigger - InDaily

Successful results of a University of Liverpool-led trial that utilized nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, a leading annual conference of HIV research, clinical practice, and progress.

The healthy volunteer trial, conducted by the collaborative nanomedicine research program led by Pharmacologist Professor Andrew Owen and Materials Chemist Professor Steve Rannard, and in collaboration with the St Stephens AIDS Trust at the Chelsea & Westminster Hospital in London, examined the use of nanotechnology to improve the delivery of drugs to HIV patients. The results were from two trials which are the first to use orally dosed nanomedicine to enable HIV therapy optimization.

Nanotechnology is the manipulation of matter on an atomic, molecular, and supramolecular scale. Nanomedicine is the application of nanotechnology to the prevention and treatment of disease in the human body. By developing smaller pills that are better for patients and less expensive to manufacture, this evolving discipline has the potential to dramatically change medical science and is already having an impact in a number of clinically used therapies and diagnostics worldwide.

Currently, the treatment of HIV requires daily oral dosing of HIV drugs, and chronic oral dosing has significant complications that arise from the high pill burden experienced by many patients across populations with varying conditions leading to non-adherence to therapies.

Recent evaluation of HIV patient groups has shown a willingness to switch to nanomedicine alternatives if benefits can be shown. Research efforts by the Liverpool team have focused on the development of new oral therapies, using Solid Drug Nanoparticle (SDN) technology which can improve drug absorption into the body, reducing both the dose and the cost per dose and enabling existing healthcare budgets to treat more patients.

The trial results confirmed the potential for a 50 percent dose reduction while maintaining therapeutic exposure, using a novel approach to formulation of two drugs: efavirenz (EFV) and, lopinavir (LPV). EFV is the current WHO-recommended preferred regimen, with 70 percent of adult patients on first-line taking an EFV-based HIV treatment regimen in low- and middle-income countries.

The trial is connected to the Universitys ongoing work as part of the multinational consortium OPTIMIZE, a global partnership working to accelerate access to simpler, safer and more affordable HIV treatment. Funded by the U.S. Agency for International Development, OPTIMIZE is led by the Wits Reproductive Health & HIV Institute in Johannesburg, South Africa, and includes the interdisciplinary Liverpool team, Columbia University, Mylan Laboratories, and the Medicines Patent Pool (MPP). OPTIMIZE is supported by key partners including UNITAID and the South African Medical Research Council (SAMRC).

Benny Kottiri, USAIDs Office of HIV/AIDS Research Division Chief, says, The potential applications for HIV treatment are incredibly promising. By aligning efforts, these integrated investments offer the potential to reduce the doses required to control the HIV virus even further, resulting in real benefits globally. This would enable the costs of therapy to be reduced which is particularly beneficial for resource-limited countries where the burden of disease is highest.

Source: University of Liverpool

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New Technique Cuts HIV Treatment in Half - Controlled Environments Magazine

EVANSTON - Northwestern Universitys International Institute for Nanotechnology (IIN) is now accepting nominations for two prestigious international prizes: the $250,000 Kabiller Prize in Nanoscience and Nanomedicine and the $10,000 Kabiller Young Investigator Award in Nanoscience and Nanomedicine.

The deadline for nominations is May 15, 2017. Details are available on the IIN website.

Our goal is to recognize the outstanding accomplishments in nanoscience and nanomedicine that have the potential to benefit all humankind, said David G. Kabiller, a Northwestern trustee and alumnus. He is a co-founder of AQR Capital Management, a global investment management firm in Greenwich, Connecticut.

The two prizes, awarded every other year, were established in 2015 through a generous gift from Kabiller. Current Northwestern-affiliated researchers are not eligible for nomination until 2018 for the 2019 prizes.

The Kabiller Prize the largest monetary award in the world for outstanding achievement in the field of nanomedicine celebrates researchers who have made the most significant contributions to the field of nanotechnology and its application to medicine and biology.

The Kabiller Young Investigator Award recognizes young emerging researchers who have made recent groundbreaking discoveries with the potential to make a lasting impact in nanoscience and nanomedicine.

The IIN at Northwestern University is a hub of excellence in the field of nanotechnology, said Kabiller, chair of the IIN executive council and a graduate of Northwesterns Weinberg College of Arts and Sciences and Kellogg School of Management. As such, it is the ideal organization from which to launch these awards recognizing outstanding achievements that have the potential to substantially benefit society.

Nanoparticles for medical use are typically no larger than 100 nanometers comparable in size to the molecules in the body. At this scale, the essential properties (e.g., color, melting point, conductivity, etc.) of structures behave uniquely. Researchers are capitalizing on these unique properties in their quest to realize life-changing advances in the diagnosis, treatment and prevention of disease.

Nanotechnology is one of the key areas of distinction at Northwestern, said Chad A. Mirkin, IIN director and George B. Rathmann Professor of Chemistry in Weinberg. We are very grateful for Davids ongoing support and are honored to be stewards of these prestigious awards.

An international committee of experts in the field will select the winners of the 2017 Kabiller Prize and the 2017 Kabiller Young Investigator Award and announce them in September.

The recipients will be honored at an awards banquet Sept. 27 in Chicago. They also will be recognized at the 2017 IIN Symposium, which will include talks from prestigious speakers, including 2016 Nobel Laureate in Chemistry Ben Feringa, from the University of Groningen, the Netherlands.

The winner of the inaugural Kabiller Prize, in 2015, was Joseph DeSimone the Chancellors Eminent Professor of Chemistry at the University of North Carolina at Chapel Hill and the William R. Kenan Jr. Distinguished Professor of Chemical Engineering at North Carolina State University and of Chemistry at UNC-Chapel Hill.

DeSimone was honored for his invention of particle replication in non-wetting templates (PRINT) technology that enables the fabrication of precisely defined, shape-specific nanoparticles for advances in disease treatment and prevention. Nanoparticles made with PRINT technology are being used to develop new cancer treatments, inhalable therapeutics for treating pulmonary diseases, such as cystic fibrosis and asthma, and next-generation vaccines for malaria, pneumonia and dengue.

Warren Chan, professor at the Institute of Biomaterials and Biomedical Engineering at the University of Toronto, was the recipient of the inaugural Kabiller Young Investigator Award, also in 2015. Chan and his research group have developed an infectious disease diagnostic device for a point-of-care use that can differentiate symptoms.

In total, the IIN represents and unites more than $1 billion in nanotechnology infrastructure, research and education. These efforts, plus those of many other groups, have helped transition nanomedicine from a laboratory curiosity to life-changing technologies that are positively impacting the world.

The IIN houses numerous centers and institutes, including the Ronald and JoAnne Willens Center for Nano Oncology, an NIH Center of Cancer Nanotechnology Excellence, an Air Force Center of Excellence for Advanced Bioprogrammable Nanomaterials, and the Convergence Science & Medicine Institute.

Link:

Nominations invited for $250,000 Kabiller Prize in Nanoscience and ... - Northwestern University NewsCenter

February 21, 2017 Credit: University of Liverpool

Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, a leading annual conference of HIV research, clinical practice and progress.

The healthy volunteer trial, conducted by the collaborative nanomedicine research programme led by Pharmacologist Professor Andrew Owen and Materials Chemist Professor Steve Rannard, and in collaboration with the St Stephen's AIDS Trust at the Chelsea & Westminster Hospital in London, examined the use of nanotechnology to improve the delivery of drugs to HIV patients. The results were from two trials which are the first to use orally dosed nanomedicine to enable HIV therapy optimisation.

Manipulation of matter

Nanotechnology is the manipulation of matter on an atomic, molecular, and supramolecular scale. Nanomedicine is the application of nanotechnology to the prevention and treatment of disease in the human body. By developing smaller pills that are better for patients and less expensive to manufacture, this evolving discipline has the potential to dramatically change medical science and is already having an impact in a number of clinically used therapies and diagnostics worldwide.

Currently, the treatment of HIV requires daily oral dosing of HIV drugs, and chronic oral dosing has significant complications that arise from the high pill burden experienced by many patients across populations with varying conditions leading to non-adherence to therapies.

Developing new therapies

Recent evaluation of HIV patient groups have shown a willingness to switch to nanomedicine alternatives if benefits can be shown. Research efforts by the Liverpool team have focused on the development of new oral therapies, using Solid Drug Nanoparticle (SDN) technology which can improve drug absorption into the body, reducing both the dose and the cost per dose and enabling existing healthcare budgets to treat more patients.

The trial results confirmed the potential for a 50 percent dose reduction while maintaining therapeutic exposure, using a novel approach to formulation of two drugs: efavirenz (EFV) and, lopinavir (LPV). EFV is the current WHO-recommended preferred regimen, with 70% of adult patients on first-line taking an EFV-based HIV treatment regimen in low- and middle-income countries.

The trial is connected to the University's ongoing work as part of the multinational consortium OPTIMIZE, a global partnership working to accelerate access to simpler, safer and more affordable HIV treatment. Funded by the U.S. Agency for International Development, OPTIMIZE is led by the Wits Reproductive Health & HIV Institute in Johannesburg, South Africa, and includes the interdisciplinary Liverpool team, Columbia University, Mylan Laboratories and the Medicines Patent Pool (MPP). OPTIMIZE is supported by key partners including UNITAID and the South African Medical Research Council (SAMRC).

Potential applications

Benny Kottiri, USAID's Office of HIV/AIDS Research Division Chief, said: "The potential applications for HIV treatment are incredibly promising. By aligning efforts, these integrated investments offer the potential to reduce the doses required to control the HIV virus even further, resulting in real benefits globally. This would enable the costs of therapy to be reduced which is particularly beneficial for resource-limited countries where the burden of disease is highest."

Explore further: New nanomedicine approach aims to improve HIV drug therapies

More information: The presentation is available online: http://www.croiwebcasts.org/console/player/33376?mediaType=slideVideo&

Cells within our bodies divide and change over time, with thousands of chemical reactions occurring within each cell daily. This makes it difficult for scientists to understand what's happening inside. Now, tiny nanostraws ...

Drugs disguised as viruses are providing new weapons in the battle against cancer, promising greater accuracy and fewer side effects than chemotherapy.

DNA, the stuff of life, may very well also pack quite the jolt for engineers trying to advance the development of tiny, low-cost electronic devices.

The precise control of electron transport in microelectronics makes complex logic circuits possible that are in daily use in smartphones and laptops. Heat transport is of similar fundamental importance and its control is ...

A new technique using liquid metals to create integrated circuits that are just atoms thick could lead to the next big advance for electronics.

The ability of small intestine cells to absorb nutrients and act as a barrier to pathogens is "significantly decreased" after chronic exposure to nanoparticles of titanium dioxide, a common food additive found in everything ...

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New nano approach could cut dose of leading HIV treatment in half - Phys.Org

The satellites are launched

Science Ministry spokesman

Two Israeli nano-satellites were successfully launched into space from India at 6am Wednesday, using a launcher from the Indian Space Research Organization.

The new nano-satellites are the size of milk cartons, allowing Israeli researchers better navigation and easy information access.

One of the satellites belongs to Ben Gurion University and will provide Israel with high-resolution photos. The BGUSAT is equipped with cameras able to detect climate trends and changes, and has a small chip allowing it to function like a larger satellite. The BGUSAT weighs 11 pounds (5 kg).

The second satellite belongs to SpacePharma, the Israeli company which first developed nano-satellites. This satellite has a mini-lab on board which conducts four experiments, some of which investigate the effect of zero gravity on different substances. The experiments are controlled by the researchers via a direct application on their smartphones. The automatic system allows the researchers to change the experiments as necessary, as well as receive data on radiation, temperature, and more. The SpacePharma satellite weights 9.92 lbs (4.5 kg) and is equipped with a camera which can take microscopic pictures.

A record 101 other satellites from around the globe left the same launcher together with the Israeli satellites. All of the satellites entered an orbit 310.75 miles (500 kilometers) high within minutes after launch.

88 of the other satellites launched on the PSLV launcher belong to a US company, three of them belong to India, and the others belong to Kazakhstan, Holland, Switzerland, and the United Arab Emirates.

Launched together, the 102 satellites weighed 1,378 kilograms. India's three satellites were released at a lower orbit, but the other 97 will orbit together with the Israeli satellites at a height of 310.75 miles (500 kilometers) from Earth.

The launcher traveled at a speed of 16780.6 mph (27,000 km per hour), which is forty times faster than the average airplane.

The Israeli satellites will serve researchers from Israel and around the world, providing information for climate research and medicine. Science, Technology and Space Minister Ofir Akunis (Likud) said, "We are proud to see how Israeli research has launched. We are proud of the Israeli researchers who developed these two small satellites, which will help us advance medical and environmental research for the sake of all humanity."

The rest is here:

Israel launches two nano-satellites - Arutz Sheva

Automated system classifies skin cancers

Skin cancer, the most common human malignancy, is usually diagnosed visually and then confirmed with follow-up biopsies and histological tests. Automated classification of skin lesions is desirable but challenging because such lesions vary greatly in appearance. Now, researchers from Stanford University have devised a deep-learning algorithm that can classify skin cancers from images. They trained the algorithm using a dataset of 129,450 clinical images representing more than 2000 different skin diseases. In tests on clinical images, the algorithm could diagnose the most common and the most deadly types of skin cancer malignant carcinomas and melanomas, respectively with equivalent performance to a group of 21 board-certified dermatologists (Nature 542 115).

"We made a very powerful machine learning algorithm that learns from data," said Andre Esteva, co-lead author of the paper and a graduate student in the Thrun lab. "Instead of writing into computer code exactly what to look for, you let the algorithm figure it out." The authors note that the system has yet to be validated in a real-world clinical setting, but has extensive potential to affect primary care. They also hope to make the algorithm smartphone compatible in the near future. "My main eureka moment was when I realized just how ubiquitous smartphones will be," added Esteva. "Everyone will have a supercomputer in their pockets with a number of sensors in it, including a camera. What if we could use it to visually screen for skin cancer? Or other ailments?"

Researchers at the University of Michigan Medical School have designed a portable cancer diagnostic system that enables faster and more accurate diagnosis of brain tumours in the operating room. Typically, after removing the tumour, the surgeon must wait 30 to 40 minutes while the tissue is sent to a pathology lab for processing, sectioning, staining, mounting and interpretation. This can delay decision-making in the operating room, while tissue processing can introduce artefacts. Instead, the Michigan researchers have developed a stimulated Raman histology (SRH) system that can provide fast analysis of fresh brain tumour samples in the operating room, with no sample processing or staining required (Nature Biomedical Engineering 1 0027).

SRH is based on stimulated Raman scattering microscopy, using a fibre-laser-based microscope. The technology produces images that are virtually coloured to highlight cellular and architectural features and are almost indistinguishable from traditionally stained samples. The researchers imaged tissue from 101 neurosurgical patients using the new approach and conventional methods. Both produced accurate results but SRH was much faster. Neuropathologists given 30 samples, processed via SRH or traditional methods, were equally likely to make a correct diagnosis with either sample. The team has also built a machine learning process that could predict brain tumour subtype with 90% accuracy. "By achieving excellent image quality in fresh tissues, we're able to make a diagnosis during surgery," said first author Daniel Orringer. "Our technique may disrupt the intraoperative diagnosis process in a great way, reducing it from a 30-minute process to about three minutes. Initially, we developed this technology as a means of helping surgeons detect microscopic tumour, but we found the technology was capable of much more than guiding surgery."

A research team headed up at the Center for Nanomedicine in the Republic of Korea has developed the Nano MRI Lamp a platform based on an MRI contrast that only "switches on" in the presence of the targeted disease. The Nano MRI Lamp technology combines two magnetic materials: a superparamagnetic quencher (magnetic nanoparticle) and a paramagnetic enhancer (MRI contrast agent). When the two materials are separated by more than 7nm, the MRI signal is on, whereas when they are placed closer than 7nm, the signal is switched off. The researchers named this approach magnetic resonance tuning (Nature Materials doi: 10.1038/nmat4846).

The team tested the Nano MRI Lamp's performance by detecting the presence of MMP-2, an enzyme that can induce tumour metastasis, in mice with cancer. They connected the two magnetic materials with a linker, bringing them close together and switching the MRI signal off. In the presence of cancer, the MMP-2 cleaves this linker, separating the materials and switching the MRI signal on. The resulting MR image thus indicated the location of the tumour, with the signal brightness correlated with MMP-2 concentration in the cancerous tissue. "The current contrast agent is like using a flashlight during a sunny day: its effect is limited. Instead, this new technology is like using a flash light at night and therefore more useful," explained team leader Jinwoo Cheon.

The first-in-human application of a PET radiotracer designed to identify both early and metastatic prostate cancer has been reported by a USChina research team. The new tracer is a Ga-68-labelled peptide BBN-RGD agent that targets both gastrin-releasing peptide receptor and integrin v3, both of which are overexpressed in prostate cancer cells. The study included 13 patients with prostate cancer (four newly diagnosed and nine post-therapy) and five healthy volunteers. PET/CT using Ga-68-BBN-RGD detected 20 bone lesions in seven patients, either with primary prostate cancer or after radical prostatectomy. No adverse side effects were found during the procedure and two-week follow-up, demonstrating the safety of the radiotracer (J. Nucl. Med. 58 228).

"Compounds capable of targeting more than one biomarker have the ability of binding to both early and metastatic stages of prostate cancer, creating the possibility for a more prompt and accurate diagnostic profile for both primary and the metastatic tumours," explained senior investigator Xiaoyuan Chen, from the Laboratory of Molecular Imaging and Nanomedicine at NIBIB. Looking ahead, Chen says that Ga-68-BBN-RGD could play a role in staging and detecting prostate cancer and provide guidance for internal radiation therapy, using the same peptide labelled with therapeutic radionuclides. He points out that larger-scale clinical investigations are warranted.

MSOM offers 3D in vivo skin mapping Raman imaging steps closer to the clinic Multifunctional bubbles image and treat PET helps quantify bone metastases response

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Research briefs: diagnostic imaging - Medical Physics Web (subscription)

Transparency Market Research Report Added "Nanomedicine Market - Global Industry Analysis, Size, Share,Growth, Trends and Forecast, 2013 - 2019"

This press release was orginally distributed by SBWire

Albany, NY -- (SBWIRE) -- 02/14/2017 -- The global nanomedicine market will exhibit a CAGR of 12.3% within a forecast period of 2013 to 2019. The market was valued at US$78.54 bn in 2012 and is expected to reach US$177.60 bn before the end of 2019, according to a research report released by market intelligence firm, Transparency Market Research. The report, titled "Nanomedicine Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast, 2013 - 2019," holds vital data on this market for to help the market stakeholders in strategic planning in the near future.

Download PDF Brochure: http://www.transparencymarketresearch.com/sample/sample.php?flag=S&rep_id=1753

According to the data given in the report, the global nanomedicine market is primarily driven by an increase in the rate of investments made into it. These investments are coming in the form of government support and collaborations within the healthcare industry. Most of the investments are made to improve the research and development efforts in the global nanomedicine market.The high rate of investments is being made to complement the rising prevalence of chronic diseases, which is increasing the number of patients with unresolved medical requirements.

Major restraints on the global nanomedicine market, as stated in the report, are the high costs associated with the development of effective nanomedicine, along with the overall insufficiency of framework in terms of regulatory guidance.The future of the global nanomedicine market could rely on a growing trend of identifying new applications in nanomedicine, along with its increasing scope of use in emerging economies.

The report provides a segmented analysis of the global nanomedicine market in terms of applications and geography.In terms of applications, the global nanomedicine market was led by the oncology segment in 2012, when it held nearly 38.0% of the market. Oncology holds a high percentage of nanomedicine use in the commercialized sense, allowing it to hold the largest share in the global nanomedicine market. The report, however, states that the oncology segment will lose market share to the cardiovascular segment, which is growing at the fastest rate due to an increasing population of geriatric citizens around the world.

The regional analysis of the global nanomedicine market provided in the report reveals Asia Pacific to exhibit the fastest CAGR of 14.6% between 2013 and 2019. This region owes its rapid growth rate to the increase in awareness of the benefits of nanomedicine usage in the treatment of chronic diseases. This is more relevant to China and India, where the growing rate of diagnosis of chronic illnesses, coupled with the increase in healthcare expenditure and collaborative efforts, is promoting the use of nanomedicine.

Till 2012, the global nanomedicine market was led by North America owing to the highly advanced infrastructure and services present in the healthcare industry. The report suggests that North America will maintain its dominance over the global nanomedicine market for the given forecast period.

The key players in the global nanomedicine market are Teva Pharmaceutical Industries Ltd., Sigma-Tau Pharmaceuticals Inc., UCB SA, Nanosphere Inc., Pfizer Inc., GE Healthcare, Merck & Co. Inc., Johnson & Johnson, Mallinckrodt plc, Celgene Corporation, Abbott Laboratories, and CombiMatrix Corp.

About Transparency Market Research Transparency Market Research (TMR) is a global market intelligence company providing business information reports and services. The company's exclusive blend of quantitative forecasting and trend analysis provides forward-looking insight for thousands of decision makers. TMR's experienced team of analysts, researchers, and consultants use proprietary data sources and various tools and techniques to gather and analyze information.

Contact Us Transparency Market Research State Tower, 90 State Street, Suite 700 Albany, NY 12207 United States Tel: +1-518-618-1030 USA - Canada Toll Free: 866-552-3453 Email: sales@transparencymarketresearch.com Website: http://www.transparencymarketresearch.com

For more information on this press release visit: http://www.sbwire.com/press-releases/global-nanomedicine-market/release-766924.htm

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Global Nanomedicine Market Is Primarily Driven by an Increase in the Rate of Investments Made Into It - Digital Journal

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Nanomedical Devices Industry Size, Application Analysis, Regional Outlook, Competitive Strategies and Forecast to 2027

Market Research Future

PUNE, MAHARASHTRA, INDIA, February 14, 2017 /EINPresswire.com/ Market Highlights Till now, around 250 nanomedicine products are being tested or used in humans. According to experts, the long-term impact of nanomedicinal products on human health and the environment is still not certain. During the last 10 years, there has been steep growth in development of devices that integrate nanomaterials or other nanotechnology. Enhancement of in vivo imaging and testing has been a highly popular area of research, followed by bone substitutes and coatings for implanted devices. The market for Nano-Medical Devices is booming.

Ask for your specific company profile and country level customization on report. Request a Sample Report @ https://www.marketresearchfuture.com/sample_request/1236

Segmentation Global Nano-Medical Devices Market has been segmented on the basis of types which comprises of Implantable Biosensors, Implantable cardioverter-Defibrillators (ICD), Implantable drug delivery system and others. On the basis of applications, the market is segmented into Disease indication, Drug release regulation, controlling fast or irregular heartbeat, consistent drug delivery and others. On the basis of end users, market is segmented into Hospitals, clinics, research institutes and others.

Key Players Stryker Corporation (U.S.) Medtronic (Ire) 3M Company (U.S.) St. Jude Medical, Inc. (U.S.) PerkinElmer, Inc. (U.S.) Starkey Hearing Technologies Smith & Nephew plc.

Regional Analysis of Nano-Medical devices Market: Globally North America is the largest market for Nano medical devices. The North American market for nanomedical devices is expected to grow at a CAGR of XX% and is expected to reach at US$ XXX Million by the end of the forecasted period. Europe is the second-largest market for Nano-Medical Devices which is expected to grow at a CAGR of XX%. Asia is the fastest growing market in the segment.

Taste the market data and market information presented through more than 85 market data tables and figures spread in 130 numbers of pages of the project report. Avail the in-depth table of content TOC & market synopsis on Global Nanomedical Devices Market Research Report- Forecast To 2027

Brief TOC of Global Nano-Medical Devices Market 1 Executive Summary 2 Scope of the Report 2.1 Market Definition 2.2 Scope of the Study 2.3 Markets Structure

3 Market Research Methodology 3.1 Research Process 3.2 Secondary Research 3.3 Primary Research 3.4 Forecast Model

4 Market Landscape 5 Industry Overview of Global Nano-Medical Devices Market 5.1 Introduction 5.2 Growth Drivers 5.3 Impact analysis 5.4 Market Challenges Continued.

Browse full Nano-Medical Devices Market @ https://www.marketresearchfuture.com/reports/nanomedical-devices-market

Study Objectives of Nanomedical devices Market: To provide detailed analysis of the market structure along with forecast for the next 10 years of the various segments and sub-segments of the nanomedical devices Market To provide insights about factors affecting the market growth To analyze the nanomedical devices Market based on various factors- price analysis, supply chain analysis, porters five force analysis etc. To provide historical and forecast revenue of the market segments and sub-segments with respect to four main geographies and their countries- Americas, Europe, Asia, and Rest of World. To provide country level analysis of the market with respect to the current market size and future prospective To provide country level analysis of the market for segments by types, by applications, by end users and sub-segments. To provide overview of key players and their strategic profiling in the market, comprehensively analyzing their core competencies, and drawing a competitive landscape for the market

About Market Research Future: At Market Research Future (MRFR), we enable our customers to unravel the complexity of various industries through our Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services.

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Nanomedical Devices Industry Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2027 - Satellite PR News (press release)

Daejeon, Korea (Scicasts) A research team led by CHEON Jinwoo at the Center for Nanomedicine, within the Institute for Basic Science (IBS), developed the Nano MRI Lamp: A new technology platform that tunes the magnetic resonance imaging (MRI) signals "ON" only in the presence of the targeted disease.

Published in Nature Materials, this study can overcome the limitations of existing MRI contrast agents.

MRI is an increasingly popular non-invasive technique for diagnosis and, importantly, does not use harmful radiation. Some tissues show a natural contrast on MRI, but for some specific types of imaging, patients are administered a MRI contrast agent to enhance the difference between the target area and the rest of the body. "Typical MRI contrast agents, like gadolinium, are injected in an "ON" state and distributed across the whole biological system with relatively large background signal," explains Director Cheon. "We found a new principle to switch the MRI contrast agent "ON" only in the location of the target." IBS scientists discovered how to switch the signal ON/OFF by using the Nano MRI Lamp.

The Nano MRI Lamp technology consists of two magnetic materials: A quencher (magnetic nanoparticle) and an enhancer (MRI contrast agent). The switch is due to the distance between the two. When the two materials are at a critical distance, farther than 7 nanometers (nm), the MRI signal is "ON", whereas when they are placed closer than 7 nm, the MRI signal is "OFF". The researchers named this phenomenon Magnetic REsonance Tuning (MRET), which is analogous to the powerful optical sensing technique called Fluorescence Resonance Energy Transfer (FRET).

The researchers tested the Nano MRI Lamp for cancer diagnosis. They detected the presence of an enzyme that can induce tumour metastasis, MMP-2 (matrix metalloproteinase-2) in mice with cancer. They connected the two magnetic materials with a linker that is naturally cleaved by MMP-2. Since the linker keeps the two materials close to each other, the MRI signal was "OFF". However, in the presence of the cancer, the linker is cleaved by MMP-2, which cause the two materials to be separated and the MRI signal switched "ON". Therefore, the MRI signal indicated the location of MMP-2, and the tumour. The scientists also found that the brightness of the MRI signal correlates with the concentration of MMP-2 in the cancerous tissue.

Most importantly, the Nano MRI Lamp remains switched off until it meets a biomarker associated with a specific disease, allowing higher sensitivity. "The current contrast agent is like using a flashlight during a sunny day: Its effect is limited. Instead, this new technology is like using a flash light at night and therefore more useful," explains Cheon.

Beyond cancer diagnosis, the Nano MRI Lamp can, in principle, be applied to investigate a variety of biological events, such as enzymolysis, pH variation, protein-protein interactions, etc. IBS scientists expect that it would be useful for both in vitro and in vivo diagnostics.

"Although we still have a long way to go, we established the principle and believe that the MRET and Nano MRI Lamp can serve as a novel sensing principle to augment the exploration of a wide range of biological systems," concludes Cheon. The research group is now working on developing safer and smarter multitasking contrast agents, which can simultaneously record and interpret multiple biological targets, and eventually allow a better understanding of biological processes and accurate diagnosis of diseases.

Article adapted from a Institute for Basic Science news release.

Publication: Distance-dependent magnetic resonance tuning as a versatile MRI sensing platform for biological targets. Jin-sil Choi et al. Nature Materials (February 06, 2017): Click here to view.

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Scientists Devise New Platform to Overcome the Limits of MRI Contrast Agents - Scicasts (press release) (blog)

The Nanomedicine Translation Advisory Board (NanomedTAB) offers a free-of-charge mentoring program to promising nanomedicine teams and projects at any stage of development to assess, advise and accelerate their translation and get to commercial application faster and more reliably. To reach this objective, the TAB counts on 11 experts from the industry, specifically recruited for their diverse, extensive and complementary experience in the translation of innovative technologies for healthcare.

The fourth TABs round is now open to companies, public and private research entities, and other organisations leading nanomedicine innovative projects in Europe. Deadline for applications is 27th February 2017.

Selected projects in this round will be invited to attend the TAB-In Session, designed as 2-hour face-to-face meetings with the experts. These meetings will be organised on 4th April 2017 in London in the framework of the European Nanomedicine Meeting 2017 (http://www.britishsocietynanomedicine.org/enm-2017-conference1.html).

Applications to the TAB should be submitted through the following link: http://www.nanomedtab.eu/?apply.

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The First European Nanomedicine Mentoring Program Launches a New Edition - Apply to boost your project ... - Cordis News

A research team led by CHEON Jinwoo at the Center for Nanomedicine, within the Institute for Basic Science (IBS), developed the Nano MRI Lamp: A new technology platform that tunes the magnetic resonance imaging (MRI) signals "ON" only in the presence of the targeted disease. Published inNature Materials, this study can overcome the limitations of existing MRI contrast agents.

MRI is an increasingly popular non-invasive technique for diagnosis and, importantly, does not use harmful radiation. Some tissues show a natural contrast on MRI, but for some specific types of imaging, patients are administered a MRI contrast agent to enhance the difference between the target area and the rest of the body. "Typical MRI contrast agents, like gadolinium, are injected in an "ON" state and distributed across the whole biological system with relatively large background signal," explains Director Cheon. "We found a new principle to switch the MRI contrast agent "ON" only in the location of the target." IBS scientists discovered how to switch the signal ON/OFF by using the Nano MRI Lamp.

The Nano MRI Lamp technology consists of two magnetic materials: A quencher (magnetic nanoparticle) and an enhancer (MRI contrast agent). The switch is due to the distance between the two. When the two materials are at a critical distance, farther than 7 nanometers (nm), the MRI signal is "ON", whereas when they are placed closer than 7 nm, the MRI signal is "OFF". The researchers named this phenomenon Magnetic REsonance Tuning (MRET), which is analogous to the powerful optical sensing technique called Fluorescence Resonance Energy Transfer (FRET).

The researchers tested the Nano MRI Lamp for cancer diagnosis. They detected the presence of an enzyme that can induce tumor metastasis, MMP-2 (matrix metalloproteinase-2) in mice with cancer. They connected the two magnetic materials with a linker that is naturally cleaved by MMP-2. Since the linker keeps the two materials close to each other, the MRI signal was "OFF". However, in the presence of the cancer, the linker is cleaved by MMP-2, which cause the two materials to be separated and the MRI signal switched "ON". Therefore, the MRI signal indicated the location of MMP-2, and the tumor. The scientists also found that the brightness of the MRI signal correlates with the concentration of MMP-2 in the cancerous tissue.

Most importantly, the Nano MRI Lamp remains switched off until it meets a biomarker associated with a specific disease, allowing higher sensitivity. "The current contrast agent is like using a flashlight during a sunny day: Its effect is limited. Instead, this new technology is like using a flash light at night and therefore more useful," explains Cheon.

Beyond cancer diagnosis, the Nano MRI Lamp can, in principle, be applied to investigate a variety of biological events, such as enzymolysis, pH variation, protein-protein interactions, etc. IBS scientists expect that it would be useful for both in vitro and in vivo diagnostics.

"Although we still have a long way to go, we established the principle and believe that the MRET and Nano MRI Lamp can serve as a novel sensing principle to augment the exploration of a wide range of biological systems," concludes Cheon. The research group is now working on developing safer and smarter multitasking contrast agents, which can simultaneously record and interpret multiple biological targets, and eventually allow a better understanding of biological processes and accurate diagnosis of diseases.

See original here:

Smarter MRI Diagnosis with Nano MRI Lamp - R & D Magazine

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Report Summary

The Japan Nanomedicine Industry Market Research Report 2017 is a professional and in-depth study on the current state of the Nanomedicine industry.

The report provides a basic overview of the industry including definitions, classifications, applications and industry chain structure. The Nanomedicine market analysis is provided for the Japan markets including development trends, competitive landscape analysis, and key regions development status.

Development policies and plans are discussed as well as manufacturing processes and Bill of Materials cost structures are also analyzed. This report also states import/export consumption, supply and demand Figures, cost, price, revenue and gross margins.

The report focuses on Japan major leading industry players providing information such as company profiles, product picture and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis is also carried out. The Nanomedicine industry development trends and marketing channels are analyzed. Finally the feasibility of new investment projects are assessed and overall research conclusions offered.

This report studies Nanomedicine focuses on top manufacturers in Japan market, with capacity, production, price, revenue and market share for each manufacturer, covering:

Affilogic

LTFN

Bergmannstrost

Grupo Praxis

Biotechrabbit

Bracco

Materials ResearchCentre

Carlina technologies

ChemConnection

CIC biomaGUNE

CIBER-BBN

Contipro

Cristal Therapeutics

DTI

Endomagnetics

Fraunhofer ICT-IMM

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Key Topics Covered:

Chapter One Industry Overview

Chapter Two Manufacturing Cost Structure Analysis of Nanomedicine

Chapter Three Technical Data and Manufacturing Plants Analysis

Chapter Four Sales Analysis of Nanomedicine by Regions, Product Type, and Applications

Chapter Five Sales Revenue Analysis of Nanomedicine by Regions,Product Type, and Applications

Chapter Six Analysis of Nanomedicine Production, Supply, Sales and Demand Market Status 2010-2016

Chapter Seven Analysis of Nanomedicine Industry Key Manufacturers

Chapter Eight Price and Gross Margin Analysis

Chapter Nine Marketing Trader or Distributor Analysis of Nanomedicine

Chapter Ten Analysis of Nanomedicine Production, Supply, Sales and Demand Development Forecast 2017-2021

Chapter Eleven Industry Chain Suppliers of Nanomedicine with Contact Information

Chapter Twelve New Project Investment Feasibility Analysis of Nanomedicine

Chapter Thirteen Conclusion of the Japan Nanomedicine Industry Report 2017

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Global Nanomedicine Industry Market Research Report 2017

China Nanomedicine Industry Market Research Report 2017

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Germany/Korea/Australia/Brazil/Russia/India/Indonesia/ Malaysia/Saudi Arabia/Middle East/Europe/Asia/Asia-Pacific/Southeast Asia/North America/ Latin America/South America/AMER/EMEA/Africa etc Countries/Regions and Sales/Industry Versions Respectively

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Japan Nanomedicine Industry Market Research Report 2017 - cHollywood News Portal (press release)

Written by AZoNanoFeb 7 2017

The Nano MRI Lamp consists of two magnetic materials: A quencher (magnetic nanoparticle) and an enhancer (MRI contrast agent). The MRI signal depends on the distance between the two materials. The enhancer produces a bright MRI signal only when it is at a critical distance of at least 7 nm away from the quencher. The signal is due to the rapid fluctuations of the electron spins of the enhancer. A fast flipping of the electron spins influences the water molecule, whose energy emission is detected as MRI signals. (CREDIT: IBS)

A new technology platform, the Nano MRI Lamp, is capable of tuning the magnetic resonance imaging (MRI) signals "ON" only in the vicinity of the targeted disease. This platform was developed by a research team led by Cheon Jinwoo at the Center for Nanomedicine, within the Institute for Basic Science (IBS).

This study can surpass the limitations of currently prevalent MRI contrast agents. The details of the research were published in Nature Materials.

MRI is a non-invasive method for diagnosis that is increasingly popular as it does not use destructive radiation. Certain tissues display a natural contrast on MRI, but for certain specific types of imaging, patients are given a MRI contrast agent to increase the difference between the target area and the rest of the body.

Typical MRI contrast agents, like gadolinium, are injected in an "ON" state and distributed across the whole biological system with relatively large background signal. We found a new principle to switch the MRI contrast agent "ON" only in the location of the target.

Cheon Jinwoo, IBS

IBS researchers discovered how to turn the signal ON/OFF using the Nano MRI Lamp.

The Nano MRI Lamp technology comprises of two magnetic materials: An enhancer (MRI contrast agent) and a quencher (magnetic nanoparticle). The switch is due to the distance between the two. When the two materials are positioned closer than 7 nm, the MRI signal is "OFF", whereas when they are at a critical distance, beyond 7 nm, the MRI signal is "ON".

The team christened this phenomenon Magnetic REsonance Tuning (MRET), which is similar to the powerful optical sensing method called Fluorescence Resonance Energy Transfer (FRET).

The Nano MRI Lamp was tested by the researchers to diagnose cancer. The presence of an enzyme that can stimulate tumor metastasis, MMP-2 (matrix metalloproteinase-2) in mice with cancer was detected. The researchers connected the two magnetic materials using a linker that is naturally cleaved by MMP-2.

As the linker maintains the two materials close together, the MRI signal was "OFF". However, when cancer was present, the linker is cleaved by MMP-2, which results in the two materials becoming separated and the MRI signal being switched "ON". Thus, the MRI signal revealed the location of MMP-2, and the tumor. The researchers also discovered that the MRI signals brightness matches with the concentration of MMP-2 in the tumor.

Most notably, the Nano MRI Lamp stays on OFF mode until it meets a biomarker linked with a specific disease, thus allowing better sensitivity.

The current contrast agent is like using a flashlight during a sunny day: Its effect is limited. Instead, this new technology is like using a flash light at night and therefore more useful.

Cheon Jinwoo, IBS

In addition to cancer diagnosis, in theory the Nano MRI Lamp can be used to analyze a number of biological events, such as pH variation, enzymolysis, and protein-protein interactions. IBS researchers suppose that it would be practical for both in vivo and in vitro diagnostics.

Although we still have a long way to go, we established the principle and believe that the MRET and Nano MRI Lamp can serve as a novel sensing principle to augment the exploration of a wide range of biological systems.

Cheon Jinwoo, IBS

The research team is currently involved in developing smarter and safer multitasking contrast agents, which can record and interpret numerous biological targets at the same time, and ultimately allow a better comprehension of biological processes and accurate diagnosis of diseases.

Read more from the original source:

New Nano MRI Lamp May Help Overcome Limitations in MRI Diagnosis - AZoNano

NLM ID: 101562615 Index Copernicus Value: 4.22

You can find a clear view of peer review process by clicking here.

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Exploitation of biomaterials, devices or methodologies on the nanoscale.

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Nanomedicine Nanotechnology Journals | Peer Review | OMICS

Nanobiotechnology, bionanotechnology, and nanobiology are terms that refer to the intersection of nanotechnology and biology.[1] Given that the subject is one that has only emerged very recently, bionanotechnology and nanobiotechnology serve as blanket terms for various related technologies.

This discipline helps to indicate the merger of biological research with various fields of nanotechnology. Concepts that are enhanced through nanobiology include: nanodevices (such as biological machines), nanoparticles, and nanoscale phenomena that occurs within the discipline of nanotechnology. This technical approach to biology allows scientists to imagine and create systems that can be used for biological research. Biologically inspired nanotechnology uses biological systems as the inspirations for technologies not yet created.[2] However, as with nanotechnology and biotechnology, bionanotechnology does have many potential ethical issues associated with it.

The most important objectives that are frequently found in nanobiology involve applying nanotools to relevant medical/biological problems and refining these applications. Developing new tools, such as peptoid nanosheets, for medical and biological purposes is another primary objective in nanotechnology. New nanotools are often made by refining the applications of the nanotools that are already being used. The imaging of native biomolecules, biological membranes, and tissues is also a major topic for the nanobiology researchers. Other topics concerning nanobiology include the use of cantilever array sensors and the application of nanophotonics for manipulating molecular processes in living cells.[3]

Recently, the use of microorganisms to synthesize functional nanoparticles has been of great interest. Microorganisms can change the oxidation state of metals. These microbial processes have opened up new opportunities for us to explore novel applications, for example, the biosynthesis of metal nanomaterials. In contrast to chemical and physical methods, microbial processes for synthesizing nanomaterials can be achieved in aqueous phase under gentle and environmentally benign conditions. This approach has become an attractive focus in current green bionanotechnology research towards sustainable development.[4]

The terms are often used interchangeably. When a distinction is intended, though, it is based on whether the focus is on applying biological ideas or on studying biology with nanotechnology. Bionanotechnology generally refers to the study of how the goals of nanotechnology can be guided by studying how biological "machines" work and adapting these biological motifs into improving existing nanotechnologies or creating new ones.[5][6] Nanobiotechnology, on the other hand, refers to the ways that nanotechnology is used to create devices to study biological systems.[7]

In other words, nanobiotechnology is essentially miniaturized biotechnology, whereas bionanotechnology is a specific application of nanotechnology. For example, DNA nanotechnology or cellular engineering would be classified as bionanotechnology because they involve working with biomolecules on the nanoscale. Conversely, many new medical technologies involving nanoparticles as delivery systems or as sensors would be examples of nanobiotechnology since they involve using nanotechnology to advance the goals of biology.

The definitions enumerated above will be utilized whenever a distinction between nanobio and bionano is made in this article. However, given the overlapping usage of the terms in modern parlance, individual technologies may need to be evaluated to determine which term is more fitting. As such, they are best discussed in parallel.

Most of the scientific concepts in bionanotechnology are derived from other fields. Biochemical principles that are used to understand the material properties of biological systems are central in bionanotechnology because those same principles are to be used to create new technologies. Material properties and applications studied in bionanoscience include mechanical properties(e.g. deformation, adhesion, failure), electrical/electronic (e.g. electromechanical stimulation, capacitors, energy storage/batteries), optical (e.g. absorption, luminescence, photochemistry), thermal (e.g. thermomutability, thermal management), biological (e.g. how cells interact with nanomaterials, molecular flaws/defects, biosensing, biological mechanisms s.a. mechanosensing), nanoscience of disease (e.g. genetic disease, cancer, organ/tissue failure), as well as computing (e.g. DNA computing)and agriculture(target delivery of pesticides, hormones and fertilizers.[8] The impact of bionanoscience, achieved through structural and mechanistic analyses of biological processes at nanoscale, is their translation into synthetic and technological applications through nanotechnology.

Nano-biotechnology takes most of its fundamentals from nanotechnology. Most of the devices designed for nano-biotechnological use are directly based on other existing nanotechnologies. Nano-biotechnology is often used to describe the overlapping multidisciplinary activities associated with biosensors, particularly where photonics, chemistry, biology, biophysics, nano-medicine, and engineering converge. Measurement in biology using wave guide techniques, such as dual polarization interferometry, are another example.

Applications of bionanotechnology are extremely widespread. Insofar as the distinction holds, nanobiotechnology is much more commonplace in that it simply provides more tools for the study of biology. Bionanotechnology, on the other hand, promises to recreate biological mechanisms and pathways in a form that is useful in other ways.

Nanomedicine is a field of medical science whose applications are increasing more and more thanks to nanorobots and biological machines, which constitute a very useful tool to develop this area of knowledge. In the past years, researchers have done many improvements in the different devices and systems required to develop nanorobots. This supposes a new way of treating and dealing with diseases such as cancer; thanks to nanorobots, side effects of chemotherapy have been controlled, reduced and even eliminated, so some years from now, cancer patients will be offered an alternative to treat this disease instead of chemotherapy, which causes secondary effects such as hair loss, fatigue or nausea killing not only cancerous cells but also the healthy ones. At a clinical level, cancer treatment with nanomedicine will consist on the supply of nanorobots to the patient through an injection that will seek for cancerous cells leaving untouched the healthy ones. Patients that will be treated through nanomedicine will not notice the presence of this nanomachines inside them; the only thing that is going to be noticeable is the progressive improvement of their health.[9]

Nanobiotechnology (sometimes referred to as nanobiology) is best described as helping modern medicine progress from treating symptoms to generating cures and regenerating biological tissues. Three American patients have received whole cultured bladders with the help of doctors who use nanobiology techniques in their practice. Also, it has been demonstrated in animal studies that a uterus can be grown outside the body and then placed in the body in order to produce a baby. Stem cell treatments have been used to fix diseases that are found in the human heart and are in clinical trials in the United States. There is also funding for research into allowing people to have new limbs without having to resort to prosthesis. Artificial proteins might also become available to manufacture without the need for harsh chemicals and expensive machines. It has even been surmised that by the year 2055, computers may be made out of biochemicals and organic salts.[10]

Another example of current nanobiotechnological research involves nanospheres coated with fluorescent polymers. Researchers are seeking to design polymers whose fluorescence is quenched when they encounter specific molecules. Different polymers would detect different metabolites. The polymer-coated spheres could become part of new biological assays, and the technology might someday lead to particles which could be introduced into the human body to track down metabolites associated with tumors and other health problems. Another example, from a different perspective, would be evaluation and therapy at the nanoscopic level, i.e. the treatment of Nanobacteria (25-200nm sized) as is done by NanoBiotech Pharma.

While nanobiology is in its infancy, there are a lot of promising methods that will rely on nanobiology in the future. Biological systems are inherently nano in scale; nanoscience must merge with biology in order to deliver biomacromolecules and molecular machines that are similar to nature. Controlling and mimicking the devices and processes that are constructed from molecules is a tremendous challenge to face the converging disciplines of nanotechnology.[11] All living things, including humans, can be considered to be nanofoundries. Natural evolution has optimized the "natural" form of nanobiology over millions of years. In the 21st century, humans have developed the technology to artificially tap into nanobiology. This process is best described as "organic merging with synthetic." Colonies of live neurons can live together on a biochip device; according to research from Dr. Gunther Gross at the University of North Texas. Self-assembling nanotubes have the ability to be used as a structural system. They would be composed together with rhodopsins; which would facilitate the optical computing process and help with the storage of biological materials. DNA (as the software for all living things) can be used as a structural proteomic system - a logical component for molecular computing. Ned Seeman - a researcher at New York University - along with other researchers are currently researching concepts that are similar to each other.[12]

DNA nanotechnology is one important example of bionanotechnology.[13] The utilization of the inherent properties of nucleic acids like DNA to create useful materials is a promising area of modern research. Another important area of research involves taking advantage of membrane properties to generate synthetic membranes. Proteins that self-assemble to generate functional materials could be used as a novel approach for the large-scale production of programmable nanomaterials. One example is the development of amyloids found in bacterial biofilms as engineered nanomaterials that can be programmed genetically to have different properties.[14]Protein folding studies provide a third important avenue of research, but one that has been largely inhibited by our inability to predict protein folding with a sufficiently high degree of accuracy. Given the myriad uses that biological systems have for proteins, though, research into understanding protein folding is of high importance and could prove fruitful for bionanotechnology in the future.

Lipid nanotechnology is another major area of research in bionanotechnology, where physico-chemical properties of lipids such as their antifouling and self-assembly is exploited to build nanodevices with applications in medicine and engineering.[15]

Meanwhile, nanotechnology application to biotechnology will also leave no field untouched by its groundbreaking scientific innovations for human wellness; the agricultural industry is no exception. Basically, nanomaterials are distinguished depending on the origin: natural, incidental and engineered nanoparticles. Among these, engineered nanoparticles have received wide attention in all fields of science, including medical, materials and agriculture technology with significant socio-economical growth. In the agriculture industry, engineered nanoparticles have been serving as nano carrier, containing herbicides, chemicals, or genes, which target particular plant parts to release their content.[16] Previously nanocapsules containing herbicides have been reported to effectively penetrate through cuticles and tissues, allowing the slow and constant release of the active substances. Likewise, other literature describes that nano-encapsulated slow release of fertilizers has also become a trend to save fertilizer consumption and to minimize environmental pollution through precision farming. These are only a few examples from numerous research works which might open up exciting opportunities for nanobiotechnology application in agriculture. Also, application of this kind of engineered nanoparticles to plants should be considered the level of amicability before it is employed in agriculture practices. Based on a thorough literature survey, it was understood that there is only limited authentic information available to explain the biological consequence of engineered nanoparticles on treated plants. Certain reports underline the phytotoxicity of various origin of engineered nanoparticles to the plant caused by the subject of concentrations and sizes . At the same time, however, an equal number of studies were reported with a positive outcome of nanoparticles, which facilitate growth promoting nature to treat plant.[17] In particular, compared to other nanoparticles, silver and gold nanoparticles based applications elicited beneficial results on various plant species with less and/or no toxicity.[18][19] Silver nanoparticles (AgNPs) treated leaves of Asparagus showed the increased content of ascorbate and chlorophyll. Similarly, AgNPs-treated common bean and corn has increased shoot and root length, leaf surface area, chlorophyll, carbohydrate and protein contents reported earlier.[20] The gold nanoparticle has been used to induce growth and seed yield in Brassica juncea.[21]

This field relies on a variety of research methods, including experimental tools (e.g. imaging, characterization via AFM/optical tweezers etc.), x-ray diffraction based tools, synthesis via self-assembly, characterization of self-assembly (using e.g. MP-SPR, DPI, recombinant DNA methods, etc.), theory (e.g. statistical mechanics, nanomechanics, etc.), as well as computational approaches (bottom-up multi-scale simulation, supercomputing).

Continued here:

Nanobiotechnology - Wikipedia

Nanomedicine Overview

What if doctors had tiny tools that could search out and destroy the very first cancer cells of a tumor developing in the body? What if a cell's broken part could be removed and replaced with a functioning miniature biological machine? Or what if molecule-sized pumps could be implanted in sick people to deliver life-saving medicines precisely where they are needed? These scenarios may sound unbelievable, but they are the ultimate goals of nanomedicine, a cutting-edge area of biomedical research that seeks to use nanotechnology tools to improve human health.

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A lot of things are small in today's high-tech world of biomedical tools and therapies. But when it comes to nanomedicine, researchers are talking very, very small. A nanometer is one-billionth of a meter, too small even to be seen with a conventional lab microscope.

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Nanotechnology is the broad scientific field that encompasses nanomedicine. It involves the creation and use of materials and devices at the level of molecules and atoms, which are the parts of matter that combine to make molecules. Non-medical applications of nanotechnology now under development include tiny semiconductor chips made out of strings of single molecules and miniature computers made out of DNA, the material of our genes. Federally supported research in this area, conducted under the rubric of the National Nanotechnology Initiative, is ongoing with coordinated support from several agencies.

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For hundreds of years, microscopes have offered scientists a window inside cells. Researchers have used ever more powerful visualization tools to extensively categorize the parts and sub-parts of cells in vivid detail. Yet, what scientists have not been able to do is to exhaustively inventory cells, cell parts, and molecules within cell parts to answer questions such as, "How many?" "How big?" and "How fast?" Obtaining thorough, reliable measures of quantity is the vital first step of nanomedicine.

As part of the National Institutes of Health (NIH) Common Fund [nihroadmap.nih.gov], the NIH [nih.gov] has established a handful of nanomedicine centers. These centers are staffed by a highly interdisciplinary scientific crew, including biologists, physicians, mathematicians, engineers and computer scientists. Research conducted over the first few years was spent gathering extensive information about how molecular machines are built.

Once researchers had catalogued the interactions between and within molecules, they turned toward using that information to manipulate those molecular machines to treat specific diseases. For example, one center is trying to return at least limited vision to people who have lost their sight. Others are trying to develop treatments for severe neurological disorders, cancer, and a serious blood disorder.

The availability of innovative, body-friendly nanotools that depend on precise knowledge of how the body's molecular machines work, will help scientists figure out how to build synthetic biological and biochemical devices that can help the cells in our bodies work the way they were meant to, returning the body to a healthier state.

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Last Updated: January 22, 2014

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Nanomedicine Fact Sheet - Genome.gov | National Human ...

Conference Series LLCinvites all the participants from all over the world to attend 10th International Conference on Nanomedicine and Nanotechnology in Health Care during July 25-27, 2016 at Avani Atrium, Bangkok, Thailand. It will include presentations and discussions to help attendees address the current trends and research on the applications of Nanomedicine and nanotechnology in healthcare. The theme of the conference is "Embarking Next Generation Delivery Vehicles for affordable Healthcare!"

Nanomedicineis innovating the healthcare industry and impacting our society, but is still in its infancy in clinical performance and applications. The aim of thisNanomedicine 2016conference is to bring together leading academic, clinical and industrial experts to discuss development of innovative cutting-edge Nanomedicine and challenges in Nanomedicine clinical translation.

Track 01:Nanomedicine

Nanomedicine applications in the field of medicine are vast. It helps in the detection, diagnosis, prevention, treatment and follow-up of many diseases.Personalized Nanomedicineis being applied in all the branches of medicine like Radiology, Neurology, Surgery, Pulmonology, Dentistry, Orthopaedics, Ophthalmology etc.Nanomedicine conferencesfocusses on how Nanomedicine can be the next delivery vehicle for making healthcare affordable.

RelatedNanomedicine Conferences|Nano science Meeting |Healthcare Meeting

Nanomaterials Conference April 21-23 2016, UAE; MedicalNanotechnologySummit June 9-11 2016, Dallas; Molecular Nanoscience Meeting September 26-28 2016, UK; Nanotechnology Expo November 10-12 2016, Australia; Nanotech Expo December 5-7 2016, USA; International Conference onNanoscienceand Nanotechnology (ICONN), 711 February 2016, Australia; International Conference onNanobiotechnology, Drug Delivery, and Tissue Engineering, 1st- 2ndApril 2016, Czech Republic; International Conference on Biotechnology, Bioengineering andNanoengineering, April 14-15, 2016, Portugal; Meeting and Expo onNanomaterialsand Nanotechnology, 25th - 27th April 2016, UAE;NANOTEXNOLOGY, 29 July, 2016, Greece, American Society For Nanomedicine, Washington, USA, Society for Personalized Nanomedicine, Florida, USA

Track 02: Nanomedicine and Drug delivery

There are a many ways thatnanotechnologycan make the delivery of drugs more systematic and accost effective treatment for the patient. Numerous biological materials like albumin, gelatine and phospholipids for liposomes, and more substances of a chemical nature like various polymers and solid metal containing nanoparticles are under investigation for preparation of nanoparticles. The hazards that are introduced by usingnanoparticles for drug deliveryare more than that posed by conventional hazards imposed by chemical delivery.

RelatedNanomedicine Conferences|Nanotechnology Conferences|Healthcare Meeting:

Bioavailability and Bioequivalence Summit August 29-31, 2016, USA;Surgical OncologyConference during September 01-03, 2016, Brazil; Precision Medicine ConferenceNovember 03-05, 2016, USA; Translational MedicineConference November 17-19, 2016, USA;Mesothelioma Summit,November 03-04, 2016, Spain; International Conference onBiotechnologyand Nanotechnology, April 14-15, 2016, Portugal;Nanotech Conference & Exhibition, 01-03 June, 2016, France; Materials Scienceand Nanotechnology Conference July 28- 29, 2016, China; 7thInternationalnanotechnology Summit: fundamentals and applications, August 19-10, 2016 Hungary, Society for Personalized Nanomedicine, Florida, USA, European Society for Nanomedicine, Basel, Switzerland

Track 03:Nanomedicine and Nanotechnology

Nanomedicine is an emerging specialty born from Nanotechnology. Bothnanomedicine and nanotechnologyare emerging as the new direction in the diagnosis and drug therapy. Nanomedicine can change the face of healthcare in the future using nanotechnology.Nanomedicinehelps detect, repair, understand and control the human biological system. Nanomedicine can be used forpersonalized Nanomedicine.

RelatedNanomedicine Conferences|Nano science Meeting |Healthcare Meeting:

Nanomaterials Conference April 21-23 2016, UAE; MedicalNanotechnologySummit June 9-11 2016, Dallas; Molecular Nanoscience Meeting September 26-28 2016, UK; Nanotechnology Expo November 10-12 2016, Australia; Nanotech Expo December 5-7 2016, USA; International Conference onNanoscienceand Nanotechnology (ICONN), 711 February 2016, Australia; International Conference onNanobiotechnology, Drug Delivery, and Tissue Engineering, 1st- 2ndApril 2016, Czech Republic, Biotechnology, Bioengineering andNanoengineering Conference, April 14-15, 2016, Portugal; Nanomaterials Conferenceand Nanotechnology, 25th - 27th April 2016, UAE;NANOTEXNOLOGY, 29 July, 2016, Greece, International Association of Nanotechnology, California, USA, French Society for Nanomedicine, Lille, France

Track 04:Nanomedicine and Nanobiotechnology

Nanobiotechnologyis the intersection of nanotechnology and biology. Nanobiotechnology has multitude of potentials for advancing medical science thereby improving health care practices around the world. Nanomedicine is used to treat diseases bygene therapy. Nano biotechnologies are being applied to molecular diagnostics and several technologies are in development.

RelatedNanomedicine Conferences|Nanotechnology Conferences|Healthcare Meeting:

NanoConference June 20-21, 2016 Cape Town, South Africa; Medical NanotechnologyCongress and Expo June 9-11, 2016 Dallas, USA; Nanotechnology Congress June 27-29, 2016 Valencia, Spain; 11th Nanobiotechnology MeetingSeptember 26-28, 2016 London, UK: Nanotechnology Expo November 10-12, 2016 Melbourne, Australia: International Conference on NanotechnologyModellingand Simulation April 1-2, 2016 Prague, Czech Republic: The 5th Conference onNanomaterialsJanuary 14-16, 2016 Bangkok, Thailand: Nanotechnology Conference and Expo Baltimore, USA, 4th to 6th April 2016: 4thNanoscience Conference (ICNT2016) Kuala Lumpur, Malaysia, 28th - 29th January 2016: 4th Conference on Materials ScienceNew York, USA, American Nano Society, Florida, USA, Sustainable Nanotechnology Organization, Washington, USA

Track 05:Nanomedicine and Bioengineering

Nanomedicinehas a considerable role in Bioengineering. To design and construct an apt scaffold is the major challenge inRegenerative medicinetoday. The cell-cell and cell-matrix interactions in the biosystems happen at the nanoscale level. Therefore the application of nanotechnology at that level helps in modifying the cellular function to mimic the native tissue in a more appropriate way. The application ofBioengineeringhas transformed the designing the manufacturing of scaffolds and artificial grafts.

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Stem Cell Research conference February 29-March 02 2016, USA, Bio banking ConferenceAugust 18-19 2016, USA; Regenerative Medicine Conference,September 12-14 2016, Germany; 6th Pharmacogenomics ConferenceSeptember 12-14, 2016, Berlin, Germany; Conference onRestorative MedicineOctober 24-26, 2016, USA ; Conference onRegeneration, January 10 14, 2016, USA; ISSCR Conference onNeural Degenerationand Disease, 18th Biotechnology Meeting, April 11-12, 2016, Italy; 14th European Symposium on Drug Delivery, 13th-15thApril 2016, The Netherlands Sustainable Nanotechnology Organization, Washington, USA, Asian Nanoscience and Nanotechnology Association, Kagawa, Japan

Track 06:Nanomedicine and Cancer

Cancer Nanomedicineaims to use the nanostructures and nanoscale processes for the prevention, detection, diagnosis and treatment of cancer and other concomitant areas. Even when molecular changes occur in a smaller percentage of cells, which may be cancer related targets.Nanomedicine in cancercan help in the sensitive detection of them. The use of Nanotechnology to combat cancer is still under development. Severalnanocarrierdrugs andnanotherapeuticsare available in market and some in Clinical trials.

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CancerDiagnostics Expo June 13-15 2016, Italy; Conference onCancer Immunologyand Immunotherapy July 28-30 2016, Australia;Cancer GenomicsSummit August 8-9 2016, USA; 12th Cancer TherapySummit September 26-28 2016, UK; International Conference onCervical CancerSeptember 22-23 2016, Austria; TheBiomarkerConference, 18th-19th February 2016, USA; Cancer Vaccines: Targeting Cancer Genes forImmunotherapy, March 610 2016, Canada; 18th Conference on Biotechnology Advances, April 11-12, 2016, Italy; 14th European Drug Delivery Summit, April 13-15 2016, The Netherlands; 18th InternationalCancer NanomedicineConference and Novel Drug Delivery Systems, April 22 - 23, 2016, United Kingdom, Asian Nanoscience and Nanotechnology Association, Kagawa, Japan, European Nanoscience and Nanotechnology Association, Bulgaria.

Track 07:Nanomedicine and Healthcare

Nanomedicineaffects almost all the aspects of healthcare. Nanomedicine helps to engineer novel and advanced tools for the treatment of various diseases and the improvement of human biosystems usingmolecular Nanotechnology. Cardiovascular diseases, Neurodegenerative disorders, Cancer, Diabetes, Infectious diseases, HIV/AIDS are the main diseases whose treatment can be benefitted by using nanomedicine.

RelatedNanomedicine Conferences|Nano science Meeting |Healthcare Meeting:

Bioequivalence and Bioavailability Summit August 29-31, 2016, USA;Surgical OncologyConference during September 01-03, 2016, Brazil; Precision Medicine ConferenceNovember 03-05, 2016, USA; Translational MedicineConference November 17-19, 2016, USA;Mesothelioma Summit,November 03-04, 2016, Spain; International Conference onBiotechnologyand Nanotechnology, April 14-15, 2016, Portugal;Nanotech Conference & Exhibition, 01-03 June, 2016, France; Materials Scienceand Nanotechnology Conference July 28- 29, 2016, China; 7thInternationalnanotechnology Summit: fundamentals and applications, August 19-10, 2016 Hungary, Society for Personalized Nanomedicine, Florida, USA, European Society for Nanomedicine, Basel, Switzerland

Track 08:Nanomedicine and Healthcare Applications

Nanomedicineapplications in healthcare Industry are broad. It helps to engineer newNano medical devices, design nanoparticles for detection and drug delivery in cancer. Nanomedicine can be applied in allied areas of healthcare like Wound healing, Food Industry and Hair growth. Nanomedicine is being widely used forpublic health and Nutrition.

RelatedNanomedicine Conferences|Nanotechnology Conferences|Healthcare Meeting:

NanoConference June 20-21, 2016 Cape Town, South Africa; Medical NanotechnologyCongress and Expo June 9-11, 2016 Dallas, USA; Nanotechnology Congress June 27-29, 2016 Valencia, Spain; 11th Nanobiotechnology MeetingSeptember 26-28, 2016 London, UK: Nanotechnology Expo November 10-12, 2016 Melbourne, Australia; International Conference on NanotechnologyModellingand Simulation April 1-2, 2016 Prague, Czech Republic: The 5th Conference onNanomaterialsJanuary 14-16, 2016 Bangkok, Thailand: Nanotechnology Conference and Expo Baltimore, USA, 4th to 6th April 2016: 4thNanoscience Conference (ICNT2016) Kuala Lumpur, Malaysia, 28th - 29th January 2016: 4th Conference on Materials ScienceNew York, USA, American Nano Society, Florida, USA, Sustainable Nanotechnology Organization, Washington, USA.

Track 09: Nanotechnology and Food

Nanotechnology has begun to find potential applications in the area of functional food by engineering biological molecules toward functions very different from those they have in nature, opening up a whole new area of research and development. Of course, there seems to be no limit to whatfood technologistsare prepared to do to our food and nanotechnology will give them a whole new set of tools to go to new extremes. Nanotechnology may revolutionize the food industry by providing stronger, high-barrier packaging materials, more potent antimicrobial agents, and a host of sensors which can detect trace contaminants, gasses or microbes in packaged foods.

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Biopolymers Congress, August 01-03, 2016, UK; Conference onSustainable BioplasticsNovember 10-12, 2016, Spain; Biopolymers andBioplastics Summit, September 12-14, 2016, USA; Biofuelsand Bioenergy September 1-3, 2016, Brazil; Public HealthSummit March 10-12, 2016, Spain; 5th Annual PharmaceuticalMicrobiology Conference, 2021 January 2016, United Kingdom; 18th International Conference on Biomaterials,Colloidsand Nanomedicine, January 21-22, 2016, France; 13th National Conference and Technology Exhibition On Medical Devices &PlasticsDisposables, February 12-13, 2016, USA; 18th International Conference onToxicology, February 25 - 26, 2016; United Kingdom; Faraday Discussion:Nanoparticleswith Morphological and Functional Anisotropy, 46 July 2016, United Kingdom, Asian Nanoscience and Nanotechnology Association, Kagawa, Japan, European Nanoscience and Nanotechnology Association, Bulgaria

Track 10:Nanomedicine and Nanotheranostics

Nanotheranosticscombine both the Non-invasive diagnosis and treatment of diseases and helps to monitor the drug release and dispersion of the drug, thereby increasing the effectiveness of therapy.Cancer nanotheranosticshold a great promise in improving the treatment outcomes in Cancer. Nanotheranostics are currently being used in theBiomarker Discovery. Nanotheranostics include both Genomics based theranostics and Proteomics based theranostics

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Pharmacology SummitAugust 08-10 2016, UK;Conference onClinical TrialsAugust 22-24 2016, USA; Neuropharmacology MeetingSeptember 15-17 2016, USA;PharmacovigilanceSummit September 19-21 2016 in Austria; Drug DiscoveryExpo October 24-26 2016, Turkey; 18th International Conference onBioengineering, Biotechnology and Nanotechnology, January 18 - 19, 2016, United Kingdom; 4thImmunogenicity& Immunotoxicity Conference January 25-26, 2016, USA; Genomics andpersonalized medicine conference, 07-11 February, 2016, Canada;Conference onAntibodiesas Drugs, 06-10 March, 2016, Canada; Pharmaceutical Sciences Congress, 28 August - 1 September 2016, Argentina, American Society For Nanomedicine , Washington, USA, Society for Personalized Nanomedicine, Florida, USA

Track 11: Nanomedicine and Nanobiology

Nano biologyis the branch where basic biology of the organism and nanotechnology meet. Nano biology helps in addressing the basic mechanisms of human health and diseases at the cellular and molecular level.Nano biologyapplied in microbiology is Nanomicrobiology. Recently certain nanoparticles are being designed to act against infections

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Conference onPharmaceutics March 07-09 2016, Spain; BiosimilarsCongress June 27-29, 2016 Valencia, Spain; Drug DeliverySummit June 30- July 02 2016, USA; Conference onPharmaceuticalRegulatory Affairs and IPR September 12-14 2016, USA; Asia Pacific MassSpectrometryCongress October 10-12 2016, Malaysia;Advanced MaterialsConference (IC2NAM), January 15th 2016; New Zealand; Modern PhenotypicDrug Discovery Summit: Defining the Path Forward, April 26, 2016; USA; 10th IEEE international Conference on Molecular Medicineand Engineering, 17-20 April 2016, Japan; 2ndDrug Delivery Meeting: Advanced Mechanisms & Product Design, May 18-19, 2016, 2016; 6th International Conference on Manipulation, Manufacturing and Measurement on theNanoscale, 18-22 July 2016, China, International Association of Nanotechnology, California, USA, French Society for Nanomedicine, Lille, France, , Asian Nanoscience and Nanotechnology Association, Kagawa, Japan, European Nanoscience and Nanotechnology Association, Bulgaria

Track 12:Nanomedicine and Nanopharmaceuticals

Nanopharmaceuticalssuch as liposomes,quantum dots, dendrimers,carbon nanotubesand polymeric nanoparticles have brought considerable changes in drug delivery and the medical system. Nanopharmaceuticals offer a great benefit for the patients in comparison with the conventional drugs. There are several advantages of these drugs such as enhanced oral bioavailability, improved dose proportionality, enhanced solubility and dissolution rate, suitability for administration and reduced food effects.

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Conference onPharmaceutics March 07-09 2016, Spain; BiosimilarsCongress June 27-29, 2016 Valencia, Spain; Drug DeliverySummit June 30- July 02 2016, USA; Conference onRegulatory Affairs and IPR September 12-14 2016, USA; Asia Pacific MassSpectrometryCongress October 10-12 2016, Malaysia;Advanced MaterialsConference (IC2NAM), January 15th 2016; New Zealand; Modern PhenotypicDrug Discovery: Defining the Path Forward, April 26, 2016; USA; 10th IEEE international Conference on Molecular Medicineand Engineering, 17-20 April 2016, Japan; 2ndDrug Delivery Meeting: Advanced Mechanisms & Product Design, May 18-19, 2016, 2016; 6th International Conference on Manipulation, Manufacturing and Measurement on theNanoscale, 18-22 July 2016, China, International Association of Nanotechnology, California, USA, French Society for Nanomedicine, Lille, France.

Track 13:Nanomedicine and Nanotoxicology

Nanotoxicologyis intended to address the toxicological activities of nanoparticles and their products to determine whether and what extent they may pose a threat to the environment and to human health and defined as the study of the nature and mechanism of toxic effects of nanoscale materials/particles on living organisms and other biological systems. It also deals with the quantitative assessment of the severity and frequency of nanotoxic effects in relation to the exposure of the organisms. The knowledge from nanotoxicology study will be the base for designing safenanomaterialsandnanoproducts,and also direct used innanomedicalsciences.

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Pharmacology andEthnopharmacology Conference May 02-04 2016, USA; Conference on Toxicogenomics June 09-10 2016, USA; Environmental ToxicologySummit August 25-26 2016, Brazil; BiosimilarsCongress September 12-14, 2016 USA; ToxicologySummit October 27-29 2016, Italy;Biosimilarsand Biologics Congress 1-2 February, 2016, Germany; The Oxford ChemicalImmunologyConference, 45 April 2016, United Kingdom; Toxicology and risk assessment conference, April 4-6, 2016; USA; 18th International Conference onBioinformaticsand Bioengineering, April 25-16, 2016, France; Toxicology Meeting, September 47, 2016, Turkey, Society for Personalized Nanomedicine, Florida, USA, European Society for Nanomedicine, Basel, Switzerland

Track 14:Nanomedicine and Nanomedical Devices

Nanomedical devicesshow great promise in various applications for health care. Many nano scale devices have already been approved by the FDA. Nano scale materials can be used as delivery mechanisms allowing cells to absorb therapeutics into the cell wall. Various nano materials are being researched for use in cancer therapeutics.Nanowiresand needles are being researched and developed for use in epilepsy and heart control.Nanosized surgical instrumentscan be used to perform microsurgeriesand better visualization of surgery.

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Generic Drug Market Expo Oct 31- Nov 02 2016, Spain; Medical Devices Expo December 1-3 2016, USA; African Surgical and Medical Devices Expo June 20-21, 2016, South Africa; Conference on Biomaterials March 14-16 2016, UK; Bioavailability & Bioequivalence Summit August 29-31 2016, USA; Microbiology Summit, 2021 January 2016, United Kingdom; 18th International Conference on Biomaterials, Colloids and Nanomedicine, January 21-22, 2016, France; 13th Medical Devices Exhibition & Plastics Disposables, February 12-13, 2016, USA; 18th International Conference on Toxicology, February 25 - 26, 2016; United Kingdom; Faraday Discussion: Nanoparticles with Morphological and Functional Anisotropy, 46 July 2016, United Kingdom, International Association of Nanotechnology, California, USA, French Society for Nanomedicine, Lille, France

Track 15:Nanomedicine and Nanodiagnostics

The use of Nanotechnology in clinical diagnosis is termed asNano diagnostics. Diagnosis at the single cell level or molecular level can be possible through Nano diagnostics. They can even be incorporated even in the current diagnostic methods like Biochips.Nanobiosensorsare promising devices for Clinical applications.

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Bioavailability and Bioequivalence Summit August 29-31, 2016, USA;Surgical OncologyConference during September 01-03, 2016, Brazil; Precision Medicine ConferenceNovember 03-05, 2016, USA; Translational MedicineConference November 17-19, 2016, USA;Mesothelioma Summit,November 03-04, 2016, Spain; International Conference onBiotechnologyand Nanotechnology, April 14-15, 2016, Portugal;Nanotech Conference & Exhibition, 01-03 June, 2016, France; Materials Scienceand Nanotechnology Conference July 28- 29, 2016, China; 7thInternationalnanotechnology Summit: fundamentals and applications, August 19-10, 2016 Hungary, Society for Personalized Nanomedicine, Florida, USA, European Society for Nanomedicine, Basel, Switzerland.

Track 15:Nanoethics and Regulations

Nanoethicsis the study ethical and social implications of nanotechnologys. It is an emerging but controversial field.Nanoethics is a debatable field.As the research is increasing on nanomedicine, there are certain regulations to increase their efficacy and address the associated safety issues. Other issues in nanoethics include areas likeresearch ethics, environment,global equity, economics, politics, national security, education, life extension and space exploration.

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Generic Drug Market Expo Oct 31- Nov 02 2016, Spain; Medical Devices Expo December 1-3 2016, USA; African Surgical and Medical Devices Expo June 20-21, 2016, South Africa; Conference on Biomaterials March 14-16 2016, UK; Bioavailability & Bioequivalence Summit August 29-31 2016, USA; Microbiology Summit, 2021 January 2016, United Kingdom; 18th International Conference on Biomaterials, Colloids and Nanomedicine, January 21-22, 2016, France; 13th Medical Devices Exhibition & Plastics Disposables, February 12-13, 2016, USA; 18th International Conference on Toxicology, February 25 - 26, 2016; United Kingdom; Faraday Discussion: Nanoparticles with Morphological and Functional Anisotropy, 46 July 2016, United Kingdom, International Association of Nanotechnology, California, USA, French Society for Nanomedicine, Lille, France.

Track 17:Nanomedicine Technologies

Nanomedicine technologiescould find an enhanced position in various areas and applications of the healthcare sector including drug delivery, drug discovery, screening and development, diagnostics and medical devices.BIOMEMSrefers to the application of micro electromechanical systems to micro- and nanosystems for genomics, proteomics, drug-delivery analysis, molecular assembly, tissue engineering, biosensor development, nanoscale imaging, etc.Nanoroboticsrefers to the still largely theoretical nanotechnology engineering discipline of designing and building nanorobots. Different companies are developing novel technologies in Nanomedicine likeNanoTherm therapyandNanobody technology. Nanomedicine in drug discovery is playing a key role in the growing part of pharmaceutical research and development.

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Pharmacology andEthnopharmacology Conference May 02-04 2016, USA; Conference on Toxicogenomics June 09-10 2016, USA; Environmental ToxicologySummit August 25-26 2016, Brazil; BiosimilarsCongress September 12-14, 2016 USA; ToxicologySummit October 27-29 2016, Italy;Biosimilarsand Biologics Congress 1-2 February, 2016, Germany; The Oxford ChemicalImmunologyConference, 45 April 2016, United Kingdom; Toxicology and risk assessment conference, April 4-6, 2016; USA; 18th International Conference onBioinformaticsand Bioengineering, April 25-16, 2016, France; Toxicology Meeting, September 47, 2016, Turkey, Society for Personalized Nanomedicine, Florida, USA, European Society for Nanomedicine, Basel, Switzerland.

Conference Series LLCinvites the contributors across the globe to participate in the premier International Conference on Nanomedicine and Nanotechnology in Health Care (Nanomedicine-2016), to discuss the theme: "Nanomedicine: The Remarkable Technology Thats Changing the Face of Healthcare The conference will be held at Avani Atrium, Bangkok, Thailand during July 25-27,2016.

Conference Series Llc organizes a conference series of 1000+ Global Events inclusive of 300+ Conferences, 500+ Upcoming and Previous Symposiums and Workshops in USA, Europe & Asia with support from 1000 more scientific societies and publishes 700+ Open access journals which contains over 30000 eminent personalities, reputed scientists as editorial board members

International Conference on Nanomedicine and Nanotechnology in Health Care (Nanomedicine 2016) aims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results about all aspects of Nanomedicine in Healthcare. It also provides the premier interdisciplinary forum for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns, practical challenges encountered and the solutions adopted in the field of Nanomedicine. The conference program will cover a wide variety of topics relevant to the nanomedicine, including: nanomedicine in drug discover and delivery, nanodiagnostics, theranostics, applications of nanomedine in healthcare applications and disease treatments.

Why to attend?

With members from around the world focused on learning about nanomedicine and its advances; this is your best opportunity to reach the largest assemblage of participants from the Nanotechnology community. Conduct presentations, distribute information, meet with current and potential scientists, make a splash with new drug developments, and receive name recognition at this 3-day event.

Target Audience:

Nanomedicine Academia Professors , Medical professionals, Nanomedicine Department heads, Nanomedicine researchers, Nanomedicine CTOs, Nanomedicine product managers, business development managers, Entrepreneurs, Industry analysts, Investors, Students, Media representatives and decision makers from all corners of Nanoscience research area around the globe.

We therefore encourage all colleagues from all over the world to participate and help us to make this an unforgettable important and enjoyable meeting.

We look forward to seeing you in Bangkok, Thailand !!!

For more

10th International conference on Nanomedince and Nantotechnology in Healthcare

July 25-27, 2016 Bangkok, Thailand

Summary of Nanomedicine Conference:

Nanomedicine 2016 welcomes attendees, presenters, and exhibitors from all over the world to Bangkok, Thailand. We are delighted to invite you all to attend and register for the 10th International conference and exhibition on Nanomedicine and Nanotechnology in Healthcare which is going to be held during July 25-27, 2016 at Bangkok, Thailand. The organizing committee is gearing up for an exciting and informative conference program including plenary lectures, symposia, workshops on a variety of topics, poster presentations and various programs for participants from all over the world. We invite you to join us at the Nanomedicine-2016, where you will be sure to have a meaningful experience with scholars from around the world. All the members of Nanomedicine 2016 organizing committee look forward to meet in person.

Scope and Importance:

The emergence of nanomedicine and the application of nanomaterials in the healthcare industry will bring about groundbreaking improvements to the current therapeutic and diagnostic scenario. Some of the drivers of this market include increasing research funding, rising government support, improved regulatory framework, technological know-how and rising prevalence of chronic diseases such as diabetes, cancers, obesity, kidney disorders, orthopedic diseases and others.

Market Analysis:

In the past few years, the global nanomedicine market has witnessed an increasing use of novel nanomaterials and emergence of nanorobotics on a global front. The market has also observed a significant demand for personalized medicines due to its ability to treat patients based on customized treatments and other medical and genetic conditions.

Overall research in various disciplines:

The North American nanomedicine market held the majority of global market share in 2012 because of the rapidly growing nanomedicine market in the Asia-Pacific, Latin American and African region, presence of large number of patented nanomedicine products and favorable regulatory framework in the region. In addition, the presence of sophisticated healthcare infrastructure supports development of advanced products such as nano probes, nanorobots, monoclonal antibody based immunoassays and nanoparticle based imaging agents for early detection of diseases.

However, the Asia-Pacific region is expected to grow at a faster CAGR owing to presence of high unmet healthcare needs, research collaborations and increase in nanomedicine research funding in emerging economies such as China, India and other economies in the region. China is expected to surpass the United States in terms of nanotechnology funding in the near future, which indicates the growth offered by this region.

Nanomedicine study in various countries:

Companies involved in Nanomedicine:

GE Healthcare, Mallinckrodt plc, Nanosphere Inc., Pfizer Inc., Merck & Co Inc., Celgene Corporation, CombiMatrix Corporation, Abbott Laboratories are some of the major companies in the Nanomedicine market.

Why Bangkok, Thailand?

Bangkok is the cultural, economic and political capital of Thailand. The city features both old-world charm and modern convenience. Many visitors in Bangkok are overwhelmed by the sheer size of the city and the vast number of attractions it has to offer. Indeed, there are many sightseeing opportunities in Bangkok, spanning for more than two centuries of rapid development following the citys founding in 1782. As Bangkok is considered a transport hub and a popular travel destination in Asia, we believe it would be beneficial to all the delegates who are attending the conference.

At present the research on nanomedicine is currently less due to the unavailability of funds and lack of proper expertise. The Asia-Pacific region is expected to grow at a faster CAGR owing to presence of high unmet healthcare needs, research collaborations and increase in nanomedicine research funding in emerging economies such as China, India and other economies in the region. China is expected to surpass the United States.

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Nanomedicine Overview

What if doctors had tiny tools that could search out and destroy the very first cancer cells of a tumor developing in the body? What if a cell's broken part could be removed and replaced with a functioning miniature biological machine? Or what if molecule-sized pumps could be implanted in sick people to deliver life-saving medicines precisely where they are needed? These scenarios may sound unbelievable, but they are the ultimate goals of nanomedicine, a cutting-edge area of biomedical research that seeks to use nanotechnology tools to improve human health.

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A lot of things are small in today's high-tech world of biomedical tools and therapies. But when it comes to nanomedicine, researchers are talking very, very small. A nanometer is one-billionth of a meter, too small even to be seen with a conventional lab microscope.

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Nanotechnology is the broad scientific field that encompasses nanomedicine. It involves the creation and use of materials and devices at the level of molecules and atoms, which are the parts of matter that combine to make molecules. Non-medical applications of nanotechnology now under development include tiny semiconductor chips made out of strings of single molecules and miniature computers made out of DNA, the material of our genes. Federally supported research in this area, conducted under the rubric of the National Nanotechnology Initiative, is ongoing with coordinated support from several agencies.

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For hundreds of years, microscopes have offered scientists a window inside cells. Researchers have used ever more powerful visualization tools to extensively categorize the parts and sub-parts of cells in vivid detail. Yet, what scientists have not been able to do is to exhaustively inventory cells, cell parts, and molecules within cell parts to answer questions such as, "How many?" "How big?" and "How fast?" Obtaining thorough, reliable measures of quantity is the vital first step of nanomedicine.

As part of the National Institutes of Health (NIH) Common Fund [nihroadmap.nih.gov], the NIH [nih.gov] has established a handful of nanomedicine centers. These centers are staffed by a highly interdisciplinary scientific crew, including biologists, physicians, mathematicians, engineers and computer scientists. Research conducted over the first few years was spent gathering extensive information about how molecular machines are built.

Once researchers had catalogued the interactions between and within molecules, they turned toward using that information to manipulate those molecular machines to treat specific diseases. For example, one center is trying to return at least limited vision to people who have lost their sight. Others are trying to develop treatments for severe neurological disorders, cancer, and a serious blood disorder.

The availability of innovative, body-friendly nanotools that depend on precise knowledge of how the body's molecular machines work, will help scientists figure out how to build synthetic biological and biochemical devices that can help the cells in our bodies work the way they were meant to, returning the body to a healthier state.

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Last Updated: January 22, 2014

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Nanomedicine Fact Sheet - Genome.gov