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Northwestern Medicine joins $20 million national uterine fibroid study

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PUBLIC RELEASE DATE:

30-Sep-2014

Contact: Kara Spak kspak@nmh.org 312-926-0755 Northwestern Memorial Hospital @NMHnews

CHICAGO Northwestern Medicine will be one of ten investigational sites for a landmark study that seeks to improve the way uterine fibroids, one of the most prevalent health issues impacting women, are treated.

The Patient-Centered Outcomes Research Institute (PCORI) and the Agency for Healthcare Research and Quality (AHRQ) today announced that AHRQ has selected the research team that will conduct a five-year, $20 million project funded by PCORI to evaluate the effectiveness of different treatment strategies for women with uterine fibroids.

Erica E. Marsh, MD, a reproductive endocrinologist with Northwestern Fertility and Reproductive Medicine, serves as the principal investigator for Northwestern's portion of the $20 million research project, which evaluates the effectiveness of different treatment strategies for women with uterine fibroids by building a national database tracking patients, treatments and outcomes.

"Right now there's very, very little clinical trial data on fibroid outcomes," said Marsh, who is also an assistant professor of Obstetrics and Gynecology-Reproductive Endocrinology & Infertility at Northwestern University Feinberg School of Medicine. "This type of study with a huge sample size in the thousands across the nation will allow us to start to tease apart some of those questions we've always asked ourselves as physicians who take care of women with fibroids. What can I tell my patients about the risk of occurrence after one treatment versus another? The impact on fertility? The likelihood that her symptoms will return? Having this type of outcomes data will allow us to answer some of those questions."

The project, a collaboration between PCORI and the AHRQ, combines the unique expertise and patient population of ten of the country's most successful uterine fibroid programs.

Uterine fibroids are the most common noncancerous tumors in women of childbearing age and the second most common reason these women undergo surgery. Uterine fibroids can lead to significant pain, bleeding, and fertility problems. Treatment options include watchful waiting; treatment with drugs or hormones, embolization, or ultrasound; and invasive procedures such as partial or total hysterectomy. However, there is little evidence about the effectiveness of these therapies or their outcomes, including fibroid reoccurrence and women's ability to have children.

The research team is composed of a research and data coordinating center based at the Duke Clinical Research Institute, and nine top-tier clinical centers, each contributing information about geographically, racially, ethnically, and clinically diverse women who have received medical or surgical treatment for uterine fibroids. Patients will be reporting on what happens to them over time after their treatment. Women who have had uterine fibroids, as well as other stakeholders, are directly involved in determining the direction of the research and are participating as active members of the research team.

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Northwestern Medicine joins $20 million national uterine fibroid study

Athletes Care Sports Medicine Centres Toronto Impressive Five Star Review by… – Video

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Primary Montessori Day School Receive Tribute & Medicine Help By Charles Myrick Of ACRX – Video

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Primary Montessori Day School Receive Tribute Medicine Help By Charles Myrick Of ACRX
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Educare de Spiritus Webinar on the Power of Alternative Medicine and Psychotherapy: the New Paradigm – Video

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Educare de Spiritus Webinar on the Power of Alternative Medicine and Psychotherapy: the New Paradigm
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New data on financial ties in medicine

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The industry spent nearly $3.5 billion on such payments in the five-month period from August through December 2013, according to the Centers for Medicare and Medicaid Services, which released data on 4.4 million payments.

The massive trove of information named companies and many of the recipients. Also listed were types of payments, with details down to travel destinations. About 546,000 clinicians and 1,360 teaching hospitals received payments. Some doctors had ownership stakes in companies.

The release is part of a new initiative called Open Payments, mandated by the Affordable Care Act. It was intended to allow patients to look up their own doctors online, but that isn't fully ready yet. In future years, the information will cover a full 12 months and will be easier to search, officials said.

Susan Phillips, a senior vice president for Penn Medicine, the university's health system, said the school did not have access to the data until Tuesday afternoon and could not immediately provide details.

The data indicate that the bulk of the Lilly money consisted of royalties for Amyvid, the company's radioactive tracing agent used to scan for signs of Alzheimer's disease. It was developed at Penn.

The Novartis payment was listed as "compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program."

Consumer groups called the data release a much-needed step toward transparency about relationships that can influence patients' care. But doctors and industry said the government rushed to release the data, and raised questions about accuracy and lack of context.

The administration said it was not pointing a finger at the medical profession or the pharmaceutical industry.

"Open Payments does not identify which financial relationships . . . could cause conflicts of interest," said Shantanu Agrawal, the agency official overseeing the project. "It simply makes the data available to the public." Under Obama, government policy has shifted toward opening the books of the medical profession.

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New data on financial ties in medicine

UI College of Medicine Proposes New Intercampus Ties to Strengthen Bioengineering

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Newswise The University of Illinois College of Medicine has presented to the universitys Board of Trustees a white paper with a series of recommendations that would integrate engineering and technology into medical training programs, develop a new bioengineering institute, and build upon research that would attract more federal dollars to the four regional College of Medicine campuses at Chicago, Peoria, Rockford and Urbana-Champaign.

The initiative would draw upon the strengths in engineering and medicine that exist across all campuses of the University of Illinois. The UI College of Medicine, based at the Chicago campus, is the largest in the nation -- and the most diverse -- and is part of a comprehensive health sciences center. The Urbana-Champaign campus, in turn, has one of the top-ranked colleges of engineering in the country, as well as renowned strengths in supercomputing, basic and applied sciences, and humanities.

The University of Illinois is well-positioned to leverage and integrate existing engineering and medical expertise to provide our students new opportunities for learning and research in bioengineering and biotechnology, said Dr. Dimitri Azar, dean of the College of Medicine. A unified College of Medicine, together with UICs six other health science colleges, have the potential to promote university-wide collaborations that take advantage of our existing strengths.

The key, Azar said, is to couple the College of Medicines access to clinical learning opportunities with the Urbana-Champaign campuss College of Engineering, which is engaged in advanced bioengineering research and device development.

We must reorganize and recruit additional faculty to support new programs that integrate engineering and medical education, Azar said.

Short-term recommendations include expanding opportunities for students at all campuses by incorporating engineering into medical training; developing a new medical engineering training track; expanding an engineering-based M.D./Ph.D. program and residency programs; and formalizing partnerships with regional health systems to expand clinical training opportunities at College of Medicine sites in Peoria and Urbana-Champaign.

All of these initiatives could be achieved relatively quickly and at modest cost, Azar said.

The proposal to establish a multi-campus Illinois Translational BioEngineering Institute within the College of Medicine -- to aid in the recruitment of additional faculty in engineering and medicine and attract more federal funding for bioengineering research -- would require additional resources, Azar said, and could be done as a final step. The recommendations are designed to be accomplished within the current unified College of Medicine structure in a step-wise fashion, leading up to the development of the institute, Azar said.

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Dan Peer seminar on Harnessing RNAi-based nanomedicines for precision medicine – Video

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Dan Peer seminar on Harnessing RNAi-based nanomedicines for precision medicine
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Dan Peer seminar on Harnessing RNAi-based nanomedicines for precision medicine - Video

Total Body Fat Burning Exercises: Medicine Ball Slams | Workout Anywhere – Video

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