Parkinson’s disease patients get free lifetime access to 23andMe personal genome service.

By Michelle Clement | February 24, 2012 |  

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23andMe are offering free lifetime access to their personal genome service to people who have been diagnosed with Parkinson’s disease for their participation in their Parkinson’s disease research initiative.

Below is a promotional video for the project that highlights Muhammad Ali’s struggle with Parkinson’s disease and his participation in 23andMe’s research program. If you or someone you know has Parkinson’s disease, watch the video, check out the website, and explore your options for participation.

About the Author: Michelle Clement has a B.Sc. in zoology and a M.Sc. in organismal biology, both from The Ohio State University. Her thesis research was on the ecophysiology of epidermal lipids and water homeostasis in house sparrows. She now works as a technical editor for The American Chemical Society. Like this blog on Facebook. Follow on Twitter @physilology.

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The views expressed are those of the author and are not necessarily those of Scientific American.

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Dopamine Improves Creativity in Parkinson’s

By Rick Nauert PhD Senior News Editor
Reviewed by John M. Grohol, Psy.D. on February 24, 2012

New research suggests administration of dopamine can uncover latent creative talents among some individuals with Parkinson’s disease.

European scientists discovered Parkinson’s disease patients can suddenly become creative when they take dopamine therapy, producing pictures, sculptures, novels and poetry. However, the extreme focus on the new interests may limit performance of normal daily tasks and social activities.

In the study, Italian researchers studied 36 patients with Parkinson’s disease — 18 with increased artistic production and 18 without — and compared them with 36 healthy controls without Parkinson’s. None of the patients had engaged in artistic hobbies before they took dopamine.

“Patients were included in the artistic group if they started working on creative projects for two or more hours a day after starting taking dopamine” explains lead author Dr Margherita Canesi.

“Our findings suggest that the patients’ newly acquired artistic skills were probably there all along, but did not start to emerge until they took the dopamine therapy.

“They did not appear to be connected with abnormal repetitive behaviors, such as impulse control disorders or punding – stereotyped behavior characterized by an intense fascination with a complex, excessive, non-goal oriented, repetitive activity.

“Other researchers have noted that altered creative drive has been observed in patients who have neurodegenerative diseases or have had a stroke. However the anatomical and physiological understanding of creativity is difficult to establish and quantify.”

Dopamine is a neurotransmitter that helps control the brain’s reward and pleasure centers. It helps to regulate movement and emotional responses and enables people to see rewards and work towards them.
A deficiency in dopamine is the critical factor influencing Parkinson’s disease. Physicians often prescribe dopamine therapy to increase dopamine levels in the brain.

Key findings of the study included:

The artwork presented by the patients was mainly drawings/paintings (83%), poetry/novels (50%) and sculpture (28%). In 78% of cases, the patients showed more than one skill, normally writing plus painting or drawing. Some of the patients produced art that was sold and books that were published, but, at the other end of the scale, some of the creative work was of a very poor quality. By using the Torrence Test of Creative Thinking to compare the three groups, the researchers showed that the artistic Parkinson’s Disease patients had similar overall and individual scores to the healthy controls. However the non-artistic patients had significantly lower overall scores than the healthy controls and significantly lower scores than the artistic patients when it came to the elaboration sub-score. There was no correlation between the Torrence Test of Creative Thinking scores and the scores obtained using the Barratt Impulsivity Scale, one of the oldest and most widely used measures of impulsive personality traits. The researchers also used the Minnesota Impulsive Disorders Interview. This showed that one creative patient was positive for compulsive sexual behaviour, one creative patient for compulsive buying and two creative and three non-creative patients for pathological gambling. However, there was little difference in the Torrence scores for patients who tested positive or negative on the Minnesota scale. None of the patients or healthy controls displayed the stereotyped behaviour measured by the Punding Rating Scale.

“In conclusion, we found that newly acquired creative drive in patients with Parkinson’s Disease, after the introduction of dopaminergic therapy, is not related to impulsivity or impulse control disorders as measured by the Barratt Impulsivity Scale or the Minnesota Impulsive Disorders Interview” says Dr Canesi.

“We believe that their desire to be creative could represent emerging innate skills, possibly linked to repetitive and reward-seeking behaviours. Further studies are needed to support our preliminary observations.”

Source: Wiley-Blackwell

Elderly man holding paint brushes photo by shutterstock.

APA Reference
Nauert PhD, R. (2012). Dopamine Improves Creativity in Parkinson’s. Psych Central. Retrieved on February 25, 2012, from http://psychcentral.com/news/2012/02/24/dopamine-improves-creativity-in-parkinson%e2%80%99s/35229.html

 

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Money for new dementia schemes

Volunteer Pat Gibson listening to a lady at a Norfolk Pabulum Cafe. The cafes are run by Age UK Norfolk and more are to be created thanks to investment in dementia projects.

A million pounds is being ploughed into new dementia care schemes in Norfolk and Suffolk, as the two counties work together to tackle one of the biggest health challenges they face.

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The number of people with dementia is predicted to rise by 51pc in the next 15 years, but in Norfolk the number is

expected to increase by 62pc in that time – pushing the total to above 20,000 – and in Suffolk by 65pc.

Last year the Norfolk and Suffolk Dementia Alliance was launched in a bid to bring together all the health, education social care, private and voluntary organisations working in this area.

The aim of the alliance is to seek out the best research, technology and training to make East Anglia a leader, nationally and internationally, in dementia care.

By working together, the alliance’s partners hope to cut out duplication, improve pathways of care for people with dementia and reduce any postcode lottery that currently exists by rolling out the most successful schemes across the two counties.

The Norfolk and Suffolk Dementia Alliance started out life as a health partnership called the Norfolk and Waveney Health Innovation and Education Cluster (HIEC), which bid for some money from the Department of Health.

It was one of the 17 successful applicants across the country and was awarded £650,000 to use research and innovation, such as assistive technologies, to help the area’s ageing population by improving services.

Now Norfolk and Suffolk county councils have stumped up around £200,000 each, and along with around £350,000 of the HIEC funding the money has now been approved for a series of schemes across the two counties.

These include new dementia cafes, hospital dementia care co-ordinators, a dementia-focused revamp of a hospital ward, reminiscence therapy training, and new physical activity groups for people with dementia.

David Edwards, chairman of the Norfolk and Suffolk Dementia Alliance, said: “This investment makes a major step forward in improving all types of dementia services, both in Norfolk and Suffolk.

“This reflects the powerful alliance of all partners which is so crucial in making significant progress for our population.”

In addition to the £750,000 investment, and funds committed to the ongoing work of creating an integrated ‘whole system’ approach, the Norfolk County Workforce Group, an NHS group aimed at developing the healthcare workforce, is putting in £130,000 of funding for a new postgraduate certificate in dementia leadership at the University of East Anglia over the next two years.

This will enable senior nurses, or health, social or residential care workers at a similar senior level to learn more about how to deliver excellent quality care for people with dementia.

The recent £1m investment is in addition to the £1.2m already invested in dementia related pilot projects such as creating dementia intensive support teams and dementia primary care practitioners funded by the primary care trust.

Willie Cruickshank, of the dementia alliance, said: “Things have got a lot better in the past two or three years in terms of how we recognise dementia but we have a long way to go.

“Times are tight and we need to not just improve what we are doing, but also improve the way we are doing it.

“I firmly believe we need to invest in great crisis prevention.”

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Saskatchewan starts to fill trial spots for controversial MS liberation therapy

REGINA – Saskatchewan multiple sclerosis patients hoping to take part in a clinical trial of a controversial treatment may soon get a call from the ministry of health.

But only around 10 per cent of those who applied will actually get that call.

Deb Jordan, a ministry spokeswoman, said 670 people had signed up as of Thursday.

The deadline to apply for the two-year, double-blind trial of liberation therapy was midnight Friday.

Jordan said names will be randomly drawn starting next week to determine who will fill 86 spots in the test taking place in Albany, N.Y.

A successful candidate must be a Saskatchewan resident, under the age of 60 and not had liberation treatment.

“Once we verify that information, then the applicant will be forwarded to the folks who are involved in the clinical trial,” said Jordan.

“I want to also emphasize that the fact that a patient may be drawn does not necessarily mean that they will move on to the clinical trial.

“There's the medical assessment that has to take place by the team and it is the … clinical team that is operating the clinical trial that will ultimately make the decisions about the patients who will be participating in the trial.”

Jordan said the process could take several months.

The treatment is based on a hypothesis by Italian vascular surgeon Dr. Paolo Zamboni that a condition he dubbed chronic cerebrospinal venous insufficiency, or CCSVI, may be linked to multiple sclerosis. The theory suggests that narrowed neck veins create a backup of blood that can lead to lesions in the brain and inflammation.

Liberation therapy involves opening up blocked neck veins.

The idea that the condition might be linked to the progressive neurological disease has divided the medical community.

Some patients have reported substantial improvements in their symptoms after the therapy. Other studies have raised doubts about its effectiveness and questioned the benefits when weighed against the risks of complications from the operation.

The procedure is not offered in Canada and some patients have travelled around the world to seek it out.

At least two Canadians have died after having the treatment.

With a population slightly more than one million, Saskatchewan has some of the highest rates of MS in the country. An estimated 3,500 Saskatchewan residents have the illness. Canada's rate of MS is among the highest in the world at 240 per 100,000 people. On the Prairies, the rate is 340 per 100,000 people.

Saskatchewan was the first province to pledge clinical trials when it put up $5 million and issued a call for proposals in October 2010. The goal was to proceed with clinical trials by the spring of 2011.

But last June, the government said only one proposal had been received and it didn't meet criteria set by an expert panel.

That's when the province looked to New York.

The double-blind aspect of the study means only half of the patients will actually receive the treatment. Patients and physicians who do the followup will not know who got the treatment.

Jordan said the number of applications is in an expected range. Not everyone would be interested, she said.

“People have to take the information and assess it and decide for themselves whether they want to participate in a clinical trial or not,” she said.

“Very clearly, while 86 Saskatchewan patients will participate in the trial, half will receive the procedure and half will not, so how that may factor into an individual patient's decision making can only be determined by them.”

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Exciting developments

The latest research on vitamin E is looking at the lesser-known forms of the vitamin, namely tocotrienols.

IF someone were to run a quick survey as to what is the most common exhortation uttered to a loved one whose health is not optimal, it would probably be, ?Take your vitamins?.

The term ?vitamins? has become part of modern popular nomenclature. It?s a quick and convenient way of assuaging the guilt felt by those who know they are not taking good care of their health.

Of course, nothing beats a healthy diet and lifestyle to take good care of health, but for many who find such activities bothersome and time-consuming, the vitamin appears, rightly or otherwise, to be somewhat of a solution.

The term vitamin describes organic substances that are chemically unrelated, but required in small quantities, for a variety of body functions. These are not manufactured by the body, so they need to be ingested to prevent disorders of metabolism. They can be broadly divided into water-soluble and fat-soluble vitamins.

Most of the vitamins we are familiar with today were ?discovered? in the early part of the 20th century. Through the years, studies have elucidated the many important functions of these substances.

In the next few months, we will be looking at one such vitamin, vitamin E, and the research that has been carried out on the many possible benefits this vitamin can confer.

Vitamin E primer

It is recorded that vitamin E was officially recognised in 1925. In 1969, the US Food and Drug Administration (FDA) formally recognised it as an essential nutrient for humans.

Vitamin E is a fat-soluble compound, and it has many biological functions, of which the best known is its antioxidant function. In a nutshell, it protects cell membranes from oxidation and destruction. Other functions include enzymatic activities, gene expression, and neurological function.

In terms of vitamin E deficiency, it is rare, and overt deficiency symptoms have not been found in healthy people who obtain little vitamin E from their diets.

However, as fat is required to absorb vitamin E, those with fat-malabsorption syndromes (such as Crohn?s Disease) are more likely to become deficient. Deficiency symptoms include peripheral neuropathy, ataxia, skeletal myopathy, retinopathy, and impairment of the immune response.

Those with inherited disorders such as Ataxia and Vitamin E Deficiency (AVED) can have such severe vitamin E deficiency that they develop nerve damage and lose the ability to walk unless they take large doses of supplemental vitamin E.

The first use for vitamin E as a therapeutic agent was conducted in 1938 by Widenbauer. He used wheat germ oil supplement that contains vitamin E on 17 premature newborn infants suffering from growth failure. Eleven out of the original 17 patients recovered and were able to resume normal growth rates.

Since then, many other studies have been carried out on vitamin E that looked at various aspects of health and metabolism.

In general, there are eight isomers of vitamin E, and these can be broadly divided into tocopherols (four sub-types) and tocotrienols (four sub-types).

Tocopherol is an important lipid-soluble antioxidant in the body. It protects cell membranes from oxidation, removing free radical intermediates and preventing oxidation reaction. Tocopherols can be found mostly in wheat germ oil, sunflower, and safflower oils.

Compared to tocopherols, tocotrienols are sparsely studied. This might be due to the fact that they were only discovered after tocopherols. Current research direction is starting to give more prominence to the tocotrienols, the lesser known but more potent antioxidants in the vitamin E family. Palm fruit oil is the richest source of tocotrienols.

Vitamin E and health

Many believe vitamin E has the potential to promote health and prevent diseases. This is because vitamin E is a powerful antioxidant, with additional roles in anti-inflammatory, inhibition of platelet aggregation, and enhancement of the immune system.

Studies, however, have shown mixed results. Several studies have associated higher vitamin E intakes with lower rates of heart diseases while randomised clinical trials raised a doubt on the efficacy of vitamin E supplements to prevent such diseases.

In general, such clinical trials have not provided evidence that intake of vitamin E supplements helps repress cardiovascular disease.

Other studies also looked at the effects of vitamin E on cancer, eye conditions and even cognitive decline. In general, these have not revealed conclusive results.

New directions in vitamin E

Over the years, research on vitamin E has looked mainly at alpha-tocopherol. And while hopes were high that vitamin E supplements would give a positive effect on health, the research does not largely support this notion. The results of the research did not look encouraging: vitamin E, even at large doses, does not decrease mortality in adults and may slightly increase it; it does not improve blood sugar control or decrease the risk of stroke; daily supplementation of vitamin E does not decrease the risk of prostate cancer.

A 2007 study concluded that supplementation with alpha-tocopherol did not reduce the risk of major cardiovascular events in middle aged and older men.

However, recent developments warrant a serious reconsideration of vitamin E. As mentioned, most of the studies above looked at the possible effects of tocopherols, not tocotrienols. Research on tocotrienols has indicated that they have neuroprotective, anti-cancer and cholesterol-lowering properties that are often not exhibited by tocopherols.

The structure of tocotrienols suggests a better penetration into tissues layered with multiple saturated fats, making them more suited for use as supplements and such.

Since the 1980s, there have been more studies on tocotrienol showing that they may be more potent in their antioxidation and other effects than the usual suspects in vitamin E.

There appears to be more to vitamin E than just tocopherols. Research has progressed to a stage where scientists have identified the additional unique properties and benefits of tocotrienols.

Malaysian connection

Looking at the overall research on vitamin E, it is prudent to take the wholesome full spectrum of vitamin E; rather than choosing between tocopherols and tocotrienols, as Mother Nature provides it.

Vitamin E supplements currently available in health food stores consist mainly of d-alpha tocopherol or d-mixed tocopherols.

It is interesting to note that the major form of vitamin E in the Western diet occurs in the form of gamma-tocopherol because of the abundance of soy and corn-derived products. On the other hand, in the Eastern diet, the major form of vitamin E is gamma-tocotrienol from palm fruit oil and rice-derived products. Maybe, the ideal vitamin E formula should consist of all the forms of tocopherols and tocotrienols.

This could explain why Carotech Inc, a public-listed company in Malaysia, is the world?s first and largest producer of natural full spectrum of tocotrienol and tocopherol-complex. It is also the only GMP-certified tocotrienol producer in the world. The company is now working with a number of leading researchers in the world, carrying out studies on tocotrienols and its effects on a wide range of health issues; from liver diseases to prostate cancer, skin rejuvenation as well as hair loss.

References:

1. Effects of vitamin E on ruminant animal ? scholarsresearchlibrary.com/ABR-vol2…/ABR-2011-2-4-244-251.

2. US National Institutes of Health ? Dietary Supplement Fact Sheet – Vit E. ods.od.nih.gov/factsheets/vitamine/.

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Ataxia Long Term Disability.MOD – Dysarthria speaker gives Long Term Disability Toastmaster speech – Video

http://www.youtube.com/watch?v=ElySddF5tqU

14-01-2010 10:05 I have ataxic dysarthria from a stroke in 3/2/08 and had Brain surgery to remove the culprit AVM in 2/26/09. The AVM Cerebellar stroke left me with speech, balance and walking disorders that I have worked hard, through therapy, to over come. I am working with UW PT and the UW speech and hearing clinic. Recovery is a full time job, but if you view other videos of me on UTube, you will see it is paying off. I use Toastmasters to keep me motivated about speaking better. I used to talk for a living so speaking well again is VERY important. The purpose of this speech was to deliver a 8-10 sales presentation that used COMPLEX mulit-sylabic words – like Long-term dis-a-bil-i-ty in-sur-ance. 10 syllables!! Whew! Getting there. (We use these Utube videos to help me practice my speech at the UW and also to track my progress with my threapist/insurance providers etc. UTube rocks! :-)

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Dementia death risk doubles on some antipsychotics

An analysis of tens of thousands of people in nursing homes in the U.S. suggests that residents who take certain antipsychotic drugs for dementia are at about double the risk of dying compared to residents not taking those specific medications.

All the residents in the study, published Friday in the British Medical Journal (BMJ), were over age 65.

The Harvard Medical School study, the largest ever undertaken among U.S. nursing home residents, focused on 75,445 nursing-home residents from 45 states from 2001 to 2005. Their risks of death were looked at during a six-month period.

The study notes that the U.S. Food and Drug Administration (FDA) warned in 2005 that atypical antipsychotic drugs — also known as second-generation antipsychotics —are associated with an increased risk of death in older people with dementia, but it wasn't know whether the risk depends on the type of drug the person is taking.

In 2008, the FDA expanded that warning to include conventional antipsychotics — also called neuroleptics — a class of drug used to relieve symptoms including hallucinations and delusions, and to calm very aggressive patients.

The Harvard researchers conclude that not all antipsychotic medication carries the same risk of death in older people, and “clinicians may want to consider this evidence when evaluating […] the best approach to treatment of behavioural problems.” They also stress the importance of prescribing such drugs in the lowest possible dose, and closely monitoring patients shortly after they start treatment.

As the population ages, dementia — the progressive deterioration in cognitive function, or the ability to process thought — is becoming a very real concern. The Alzheimer Society of Canada, which is lobbying the Canadian government to create a plan to respond to concerns that more than 500,000 people have Alzheimer's or other dementia, with that number expected to double by 2038.

In the U.S., the number of people with some form of dementia is estimated at up to five million.

In the Harvard study, the antipsychotic drugs taken by nursing-home residents included:

Aripiprazole.

Haloperidol.

Olanzapine.

Quetiapine.

Risperidone.

Ziprasidone.

Out of the 75,445 residents, a total of 6,598 died within the six-month study from non-cancer related causes. Patients treated with haloperidol had double the risk of death compared to those taking risperidone, while those taking quetiapine had a reduced risk.

The effect of haloperidol was strongest during the first 40 days of treatment, and that did not change after the dosage was adjusted. Almost half of deaths (49 per cent) were recorded as due to circulatory disorders, 10 per cent due to to brain disorders and 15 due to respiratory disorders.

Besides age, gender and whether a patient had any physical illnesses or lived in a part of the U.S. that may raise their risk of death, the state of the nursing homes they were in — including their size, the occupancy rate, availability of special-care units and staffing levels — were taken into consideration.

The study was partially funded by U.S. National Institute of Mental Health, and researchers reported no funding or relationships with any organizations that may have influenced their work.

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Autism Detection Is Delayed in Minorities

By Rick Nauert PhD Senior News Editor
Reviewed by John M. Grohol, Psy.D. on February 22, 2012

A new study suggests the symptoms of autism in toddlers from a minority background are more significant than those noted in age-equivalent Caucasian children.

The investigation was the first prospective study of ethnic differences in the symptoms of autism among toddlers.

Researchers determined minority toddlers have more delayed language, communication and gross motor skills than Caucasian children with the disorder. Researchers at the Kennedy Krieger Institute believe subtle developmental delays may be going unaddressed in minority toddlers until more severe symptoms develop.

Autistic spectrum disorders are found in equal prevalence among all racial and ethnic groups. However, some studies have shown that children of African American, Hispanic and Asian descent are less likely to receive an early diagnosis of autism than Caucasian children.

In this new study, Rebecca Landa, Ph.D., director of the Center for Autism and Related Disorders at the institute, investigated whether the symptoms of autism in toddlers play a role in this disparity in diagnosis.

“We found the toddlers in the minority group were significantly further behind than the non-minority group in development of language and motor skills and showed more severe autism symptoms in their communication abilities,” says Landa, whose study included children and parents of African American, Asian and Hispanic descent.

“It’s really troubling when we look at these data alongside diagnosis statistics because they suggest that children in need of early detection and intervention are not getting it.”

The study is published in the Journal of Autism and Developmental Disorders.

Researchers examined development in 84 toddlers with ASD at an average 26-28 months of age using three standardized instruments that evaluate child development.

Children were evaluated by their caregivers using the Communication and Symbolic Behavior Scales Developmental Caregiver Questionnaire (CSBS-DP CQ) and by research clinicians using the Mullen Scales of Early Learning and the Autism Diagnostic Observation Schedule-Generic (ADOS).

Researchers then controlled for participants’ socioeconomic status. All three tools indicated a significant difference between minority and non-minority children.

Previous studies show that detection of ASD is possible at as early as 14 months of age. While early diagnosis is crucial for accessing intervention services, studies examining children from minority groups suggest considerable delays in the diagnosis of ASD in these children relative to their Caucasian peers.

The results may stem from cultural differences in what communities perceive as typical and atypical development in young children, the relationships between families and respected community physicians, and the stigma that some cultures place on disability as areas where education and awareness could have meaningful impact.

“Addressing cultural influences gives us a clear target to improve service delivery to minority children, but these findings may also suggest biological and other culturally related differences between Caucasian and minority children with autism,” Landa said.

“There are other complex diseases that present differently in different ethnic groups and more research is needed to investigate this possibility.”

Landa has since initiated a new study that will document the age at which minority parents first noticed signs of developmental disruption in their children, the specific nature of the behavior that concerned them, and the children’s intervention history.

Additional research is also needed to study group-specific differences in the presentation of autism symptoms between a variety of minority groups.

“Although questions remain on why these differences exist, by taking steps to develop more culturally sensitive screening and assessment practices, with a special focus on educating parents, clinicians and health educators, I believe we can empower parents to identify early warning signs and ensure minority children have the same access to services as their Caucasian peers,” said Landa.

Source: Kennedy Krieger Institute

Upset Toddler photo by shutterstock.

APA Reference
Nauert PhD, R. (2012). Autism Detection Is Delayed in Minorities. Psych Central. Retrieved on February 26, 2012, from http://psychcentral.com/news/2012/02/22/autism-detection-is-delayed-in-minorities/35136.html

 

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Training parents is good medicine for children with autism behavior problems, study suggests

ScienceDaily (Feb. 24, 2012) — Children with autism spectrum disorders who also have serious behavioral problems responded better to medication combined with training for their parents than to treatment with medication alone, Yale researchers and their colleagues report in the February issue of Journal of the American Academy of Child & Adolescent Psychiatry.

“Serious behavioral problems interfere with everyday living for children and their families,” said senior author on the study Lawrence Scahill, professor at Yale University School of Nursing and the Child Study Center. “Decreasing these serious behavioral problems results in children who are more able to manage everyday living.”

Scahill and his team completed a federally funded multi-site trial on 124 children ages 4 to 13 with autism spectrum disorders at three U.S. sites including Yale, Ohio State University, and Indiana University. In addition to autism spectrum disorders, children in the study had serious behavioral problems, including multiple and prolonged tantrums, aggression, and/or self-injurious behavior on a daily basis.

The children in the study were randomly assigned to medication alone for six months or medication plus a structured training program for their parents for six months. Parent training included regular visits to the clinic to teach parents how to respond to behavior problems to help children adapt to daily living situations. The study medication, risperidone, is approved for the treatment of serious behavioral problems in children with autism.

“In a previous report from this trial, we showed that the combined treatment was superior to medication alone in reducing the serious behavioral problems,” said Scahill. “In the current report, we show that combination treatment was better than medication alone on measures of adaptive behavior. We note that both groups — medication alone and combined treatment group — demonstrated improvement in functional communication and social interaction. But the combined group showed greater improvement on several measures of everyday adaptive functioning.”

Based on these findings, Scahill and his team are now conducting a study that uses parent training as a stand-alone strategy in treating younger children with autism spectrum disorders. This study is being conducted at Yale and four other medical centers across the country. The investigators also plan to publish the parent training manuals as a way to share this intervention with the public.

Other authors on the study included Christopher J. McDougle, Michael G. Aman, Cynthia Johnson, Benjamin Handen, Karen Bearss, James Dziura, Eric Butter, Naomi G. Swiezy, L. Eugene Arnold, Kimberly A. Stigler, Denis D. Sukhodolsky, Luc Lecavalier, Stacie L. Pozdol, Roumen Nikolov, Jill A. Hollway, Patricia Korzekwa, Allison Gavaletz, Arlene E. Kohn, Kathleen Koenig, Stacie Grinnon, James A. Mulick, Sunkyung Yu, and Benedetto Vitiello.

The National Institute of Mental Health funded the study. The work was also funded, in part, by the Yale Clinical and Translational Science Award (CTSA) grant from the National Center for Research Resources at the National Institutes of Health.

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The above story is reprinted from materials provided by Yale University. The original article was written by Karen N. Peart.

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Journal Reference:

Lawrence Scahill, Christopher J. McDougle, Michael G. Aman, Cynthia Johnson, Benjamin Handen, Karen Bearss, James Dziura, Eric Butter, Naomi G. Swiezy, L. Eugene Arnold, Kimberly A. Stigler, Denis D. Sukhodolsky, Luc Lecavalier, Stacie L. Pozdol, Roumen Nikolov, Jill A. Hollway, Patricia Korzekwa, Allison Gavaletz, Arlene E. Kohn, Kathleen Koenig, Stacie Grinnon, James A. Mulick, Sunkyung Yu, Benedetto Vitiello. Effects of Risperidone and Parent Training on Adaptive Functioning in Children With Pervasive Developmental Disorders and Serious Behavioral Problems. Journal of the American Academy of Child & Adolescent Psychiatry, 2012; 51 (2): 136 DOI: 10.1016/j.jaac.2011.11.010

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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In Saguenay, a family takes on a disease that haunts the region

Sonia Gobeil can trace her ancestors to the pioneers who first settled the isolated Saguenay region northeast of Quebec City, but she had never heard of the devastating brain disease they passed on through their genes until her son was diagnosed with it.

The disease, an inherited form of ataxia, affects the part of the brain that co-ordinates movement. It can skip generations and miss entire branches of family trees, only to pop up according to the laws of genetics and chance, leaving most patients in a wheelchair by the time they are 40. It is more common in the Saguenay and Charlevoix regions of Quebec than anywhere else in the world.

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The history of the disease there begins with a small population of immigrants from France who first settled the Charlevoix region in the 17th century. Researchers suspect that several of those people carried a copy of a rare genetic mutation that on its own is benign, but can wreak havoc in the brains of those unlucky enough to inherit two copies – one from each parent.

The population grew and, 100 years later, the migrants pushed the government to open the territory around the Saguenay River for settlement. There, they carved out a society in the forested wilderness, largely cut off from the rest of the province and generating their own distinctive genetic map. For generations, families were large – 11 children a household on average in the early 1900s – and marriages outside the Catholic faith were discouraged by the church. The Saguenay also got few newcomers. The first passable road to Quebec City, 200 kilometres away, was opened in 1951.

Today, the Saguenay remains strikingly homogeneous: 98 per cent of its 273,000 residents are francophone Quebeckers, and immigrants make up less than 1 per cent of the population.

The remoteness has produced a form of proud self-reliance, a trait that’s now being put to the service of probing the region’s genetic history and dealing with its legacy. In addition to autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), which Ms. Gobeil’s two sons have, three other genetic diseases are much more common in the region than elsewhere in the world. One causes a buildup of lactic acid in blood and can be deadly; another is an enzyme deficiency that can lead to liver and kidney failure. The third causes a birth defect in which the structure that connects the two hemispheres of the brain is missing or only partially formed. Since 2010, couples have had access to free genetic screening. About 1,800 people have been screened so far for the diseases, which affect one in five in the region. A local group goes into elementary and high schools to teach children about hereditary diseases, using simple devices like beaded necklaces to explain DNA and genetics.

Ms. Gobeil’s first born, François, was three when his pre-school teachers noticed that his gait was awkward when he ran. She and husband Jean Groleau didn’t think the problem was serious. They were shocked when doctors diagnosed the boy, now nine, with ARSACS. Their second son, Laurent, who is now six, also has the disease. François can’t skate or play hockey, which he loves. Both boys have a stiff left leg.

After François was diagnosed, the couple learned there was no treatment and no research under way to find one.

“Knowing there was no research being done was like a punch in the stomach. But at the same time, we saw it as an open door.” The condition is hereditary; we can’t change that they have it. But with research, we can do something about it and try to change the path of the future,” said Ms. Gobeil, a lawyer in Montreal.

Follow this link:
In Saguenay, a family takes on a disease that haunts the region

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Easily Treat Your Dis-ease 1/3 – Video

24-02-2012 09:52 Reverse over 900 Diseases with Nutrition "Unless we put medical freedom into the Constitution, the time will come when medicine will organize into an undercover dictatorship to restrict the art of healing to one class of Men and deny equal privileges to others; the Constitution of the Republic should make a Special privilege for medical freedoms as well as religious freedom." Presented By; http://www.RockinRon.YoungevityOnline.com How to Survive and Thrive and more interviews http://www.infowarsteam.com Dr. Benjamin Rush warned about loss of medical freedom over 200 years ago JD Heyes Natural News February 7, 2012 http://www.naturalnews.com (NaturalNews) For those of you worried about maintaining your medical freedom in the age of rising authoritarianism, it may comfort you to know that at least one of our country's founding fathers shared your concerns.

See more here:
Easily Treat Your Dis-ease 1/3 - Video

Significant state-by-state differences in black, white life expectancy

ScienceDaily (Feb. 24, 2012) — A UCLA-led group of researchers tracing disparities in life expectancy between blacks and whites in the U.S. has found that white males live about seven years longer on average than African American men and that white women live more than five years longer than their black counterparts.

But when comparing life expectancy on a state-by-state basis, the researchers made a surprising discovery: In those states in which the disparities were smallest, the differences often were not the result of African Americans living longer but of whites dying younger than the national average. And, interestingly, the area with the largest disparities wasn't a state at all but the nation's capital, Washington D.C.

The findings are published in the February issue of the peer-reviewed journal Health Services Research.

"In health-disparities research, there is an assumption that large disparities are bad because vulnerable populations are not doing as well as they should, while areas with small disparities are doing a better job at health equity," said Dr. Nazleen Bharmal, the study's lead researcher and a clinical instructor in the division of general internal medicine and health services research at the David Geffen School of Medicine at UCLA. "In our study, we show that the reason there are small disparities in life expectancy is because white populations are doing as poorly as black populations, and the goal in these states should be to raise health equity for all groups."

The data on which the researchers relied included both health-related and non-health-related deaths, such as murder and accidents. The findings, however, still highlight the need to improve the health of the nation's African Americans, the researchers said.

The research team studied death-certificate data from the U.S. Multiple Cause of Death for the years 1997-2004. The data covered 17,834,236 individuals in all 50 states and the District of Columbia. The researchers noted race/ethnicity, sex, the age at death and the state where each subject was born, lived and died.

Overall, the national life expectancy was 74.79 years for white men and 67.66 years for black men. Among women, the average life span was 79.84 years for whites and 74.64 for blacks. In every state, gaps were narrower between women than men.

New Mexico had the smallest disparities between blacks and whites (3.76 years for men and 2.45 years for women), while the District of Columbia had the largest (13.77 years for men and 8.55 years for women).

States with the largest disparities

In addition to Washington, D.C., the states with the largest disparities between white and black men were New Jersey, Nebraska, Wisconsin, Michigan, Pennsylvania and Illinois; in these states, the gap was greater than eight years because African American men's lives were shorter than the national average for black men and white men's life spans were equal to or greater than the national average.

For women, the states with the largest disparities in longevity were Illinois, Rhode Island, Kansas, Michigan, New Jersey, Wisconsin, Minnesota, Iowa, Florida and Nebraska, where the difference between black and white women was more than six years. White women in these states lived longer than average, while black women had average or lower life expectancy.

States with the smallest disparities

In addition to New Mexico, which had the smallest disparities, eight other states had black-white disparities of less than six years among men: Kentucky, West Virginia, Nevada, Oklahoma, Washington, Colorado, New York and Arizona.

In four of these states -- Kentucky, West Virginia, Nevada and Oklahoma -- the smaller disparities were due to a combination of African American men living longer than the national average and whites having shorter lives. But in New Mexico, Washington, Colorado, New York and Arizona, both black and white men lived longer than average, with black men having life spans that were particularly longer than the national average.

Among women, the states with the smallest differences were New Mexico, New York, West Virginia, Kentucky and Alabama -- each with disparities of less than four years. These smaller disparities were the result of black women being longer-lived than average and whites being shorter-lived.

Fifty-eight percent of African Americans live in 10 states: New York, California, Texas, Florida, Georgia, Illinois, North Carolina, Maryland, Missouri and Louisiana. Eliminating the disparities in just these states, the researchers said, would bring the national disparity down substantially. For instance, eliminating the disparity in Florida alone would reduce the national disparity from 7.13 years to 6.63 years for men and from 5.20 years to 4.74 years for women.

Because disease prevention and health promotion efforts identify and monitor magnitudes in disparities, these findings could point to new ways that government agencies can track and measure differences in health outcomes, the authors write. Also, the researchers feel that these differences in life expectancy should be considered when funding health programs at local and national levels. Finally, they write, state governments should consider these differences in black-white longevity in formulating health policy, given that coverage through health programs such as Medicaid varies widely among states.

There are some limitations to the study. Among them, the researchers did not account for population changes during the years covered in their analysis, though, they said, it is doubtful such changes would alter the overall findings. Also, they did not consider the tendency of people to move from place to place, which could influence health. They also could not use data from 11 states, but those areas had such small numbers of African Americans that the estimates would not have been reliable.

Also, the study covered all causes of mortality, including murder and accidental deaths. Going forward, the researchers plan to investigate disparities in life expectancy by cause of death.

In addition to Dr. Nazleen Bharmal, researchers included Chi-Hong Tseng and Mitchell Wong of UCLA and Robert Kaplan of the National Institutes of Health.

Bharmal was funded by the Robert Wood Johnson Clinical Scholars Program and a National Research Service Award Fellowship at UCLA.

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The above story is reprinted from materials provided by University of California - Los Angeles Health Sciences.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Nazleen Bharmal, Chi-Hong Tseng, Robert Kaplan, Mitchell D. Wong. State-Level Variations in Racial Disparities in Life Expectancy. Health Services Research, 2012; 47 (1pt2): 544 DOI: 10.1111/j.1475-6773.2011.01345.x

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

See original here:
Significant state-by-state differences in black, white life expectancy

Medical Update: Parkinson’s Disease Research – Video

http://www.youtube.com/watch?v=-7lmNqIEuzw

09-11-2011 17:09 David Eidelberg, MD, Director of the Leonard and Susan Feinstein Center for Neurosciences at the Feinstein Institute for Medical Research, discusses new, innovative and non-invasive methods to capture better images of a patients’ brain circuitry, eventually leading to earlier and better diagnoses, and the development of effective treatments for Parkinson’s and other diseases. Topics include: The Feinstein Institute’s endowment as one of the select Morris K. Udall Centers of Excellence in Parkinson’s Disease Research, the affiliation agreement between the Feinstein Institute and the Thomas Hartman Foundation for Parkinson’s Research to better understand Parkinson’s, comparisons of MRI, PetScan and other testing methods, the ability to measure side effects from levodopa, and the ability to scan the brain throughout the course of the disease to identify damaged brain circuits at the earliest stage.

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Medical Update: Parkinson’s Disease Research – Video

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Study Shows Differences in Black, White Life Expectancy

For Immediate Use
Feb. 24, 2012

Smaller disparities often due to whites being shorter-lived than average

Newswise — A UCLA-led group of researchers tracing disparities in life expectancy between blacks and whites in the U.S. has found that white males live about seven years longer on average than African American men and that white women live more than five years longer than their black counterparts.

But when comparing life expectancy on a state-by-state basis, the researchers made a surprising discovery: In those states in which the disparities were smallest, the differences often were not the result of African Americans living longer but of whites dying younger than the national average. And, interestingly, the area with the largest disparities wasn't a state at all but the nation's capital, Washington D.C.

The findings are published in the February issue of the peer-reviewed journal Health Services Research.

"In health-disparities research, there is an assumption that large disparities are bad because vulnerable populations are not doing as well as they should, while areas with small disparities are doing a better job at health equity," said Dr. Nazleen Bharmal, the study's lead researcher and a clinical instructor in the division of general internal medicine and health services research at the David Geffen School of Medicine at UCLA. "In our study, we show that the reason there are small disparities in life expectancy is because white populations are doing as poorly as black populations, and the goal in these states should be to raise health equity for all groups."

The data on which the researchers relied included both health-related and non–health-related deaths, such as murder and accidents. The findings, however, still highlight the need to improve the health of the nation's African Americans, the researchers said.

The research team studied death-certificate data from the U.S. Multiple Cause of Death for the years 1997–2004. The data covered 17,834,236 individuals in all 50 states and the District of Columbia. The researchers noted race/ethnicity, sex, the age at death and the state where each subject was born, lived and died.

Overall, the national life expectancy was 74.79 years for white men and 67.66 years for black men. Among women, the average life span was 79.84 years for whites and 74.64 for blacks. In every state, gaps were narrower between women than men.

New Mexico had the smallest disparities between blacks and whites (3.76 years for men and 2.45 years for women), while the District of Columbia had the largest (13.77 years for men and 8.55 years for women).

States with the largest disparities

In addition to Washington, D.C., the states with the largest disparities between white and black men were New Jersey, Nebraska, Wisconsin, Michigan, Pennsylvania and Illinois; in these states, the gap was greater than eight years because African American men's lives were shorter than the national average for black men and white men's life spans were equal to or greater than the national average.

For women, the states with the largest disparities in longevity were Illinois, Rhode Island, Kansas, Michigan, New Jersey, Wisconsin, Minnesota, Iowa, Florida and Nebraska, where the difference between black and white women was more than six years. White women in these states lived longer than average, while black women had average or lower life expectancy.

States with the smallest disparities

In addition to New Mexico, which had the smallest disparities, eight other states had black–white disparities of less than six years among men: Kentucky, West Virginia, Nevada, Oklahoma, Washington, Colorado, New York and Arizona.

In four of these states — Kentucky, West Virginia, Nevada and Oklahoma — the smaller disparities were due to a combination of African American men living longer than the national average and whites having shorter lives. But in New Mexico, Washington, Colorado, New York and Arizona, both black and white men lived longer than average, with black men having life spans that were particularly longer than the national average.

Among women, the states with the smallest differences were New Mexico, New York, West Virginia, Kentucky and Alabama — each with disparities of less than four years. These smaller disparities were the result of black women being longer-lived than average and whites being shorter-lived.

Fifty-eight percent of African Americans live in 10 states: New York, California, Texas, Florida, Georgia, Illinois, North Carolina, Maryland, Missouri and Louisiana. Eliminating the disparities in just these states, the researchers said, would bring the national disparity down substantially. For instance, eliminating the disparity in Florida alone would reduce the national disparity from 7.13 years to 6.63 years for men and from 5.20 years to 4.74 years for women.

Because disease prevention and health promotion efforts identify and monitor magnitudes in disparities, these findings could point to new ways that government agencies can track and measure differences in health outcomes, the authors write. Also, the researchers feel that these differences in life expectancy should be considered when funding health programs at local and national levels. Finally, they write, state governments should consider these differences in black–white longevity in formulating health policy, given that coverage through health programs such as Medicaid varies widely among states.

There are some limitations to the study. Among them, the researchers did not account for population changes during the years covered in their analysis, though, they said, it is doubtful such changes would alter the overall findings. Also, they did not consider the tendency of people to move from place to place, which could influence health. They also could not use data from 11 states, but those areas had such small numbers of African Americans that the estimates would not have been reliable.

Also, the study covered all causes of mortality, including murder and accidental deaths. Going forward, the researchers plan to investigate disparities in life expectancy by cause of death.

In addition to Dr. Nazleen Bharmal, researchers included Chi-Hong Tseng and Mitchell Wong of UCLA and Robert Kaplan of the National Institutes of Health.

Bharmal was funded by the Robert Wood Johnson Clinical Scholars Program and a National Research Service Award Fellowship at UCLA.

General Internal Medicine and Health Services Research is a division within the department of medicine at the David Geffen School of Medicine at UCLA. It provides a unique interactive environment for collaborative efforts between health services researchers and clinical experts with experience in evidence-based work. The division's 100-plus clinicians and researchers are engaged in a wide variety of projects that examine issues related to access to care, quality of care, health measurement, physician education, clinical ethics and doctor–patient communication. The division's researchers have close working relationships with economists, statisticians, social scientists and other specialists throughout UCLA and frequently collaborate with their counterparts at the RAND Corp. and Charles Drew University.

For more news, visit the UCLA Newsroom and follow us on Twitter.

Comment/Share

See the original post:
Study Shows Differences in Black, White Life Expectancy

Easily Treat Your Dis-ease 3/3 – Video

24-02-2012 10:03 Reverse over 900 Diseases with Nutrition "Unless we put medical freedom into the Constitution, the time will come when medicine will organize into an undercover dictatorship to restrict the art of healing to one class of Men and deny equal privileges to others; the Constitution of the Republic should make a Special privilege for medical freedoms as well as religious freedom." Presented By; http://www.RockinRon.YoungevityOnline.com How to Survive and Thrive and more interviews http://www.infowarsteam.com Dr. Benjamin Rush warned about loss of medical freedom over 200 years ago JD Heyes Natural News February 7, 2012 http://www.naturalnews.com (NaturalNews) For those of you worried about maintaining your medical freedom in the age of rising authoritarianism, it may comfort you to know that at least one of our country's founding fathers shared your concerns.

See original here:
Easily Treat Your Dis-ease 3/3 - Video

New Roles for Increasing Percentage of Older Citizens in an Aging America

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Senior Citizen Longevity & Statistics

New Roles for Increasing Percentage of Older Citizens in an Aging America

Number of older people is only natural resource that's actually growing, says Stanford Center on Longevity's Laura Carstensen. Chance to improve transportation, redesign the suburbs and gain from the talents and experience of our elders

By Stephen Tung

Laura Carstensen, director of the Stanford Center on Longevity

Feb. 21, 2012 - As the United States grows older ? with 10,000 people turning 65 every day ? and the number of people over 60 expected to surpass those under 15 within four years, common fears can play across the mind: dwindling Social Security, infirm elders, a smaller workforce and delayed retirement.

But that's only part of the picture, said Laura Carstensen, director of the Stanford Center on Longevity.

"The shame is that we're only looking at the problems," she said. "There are problems, but we're not looking for opportunities."

"It's surprising to people when you say something like the number of older people in the world is the only natural resource that's actually growing," she said.

In her talk Friday in Vancouver at the annual meeting of the American Association for the Advancement of Science, Carstensen discussed not only the need for social and scientific accommodations for an aging population, but also new roles for older people. The talk was, "Challenges and Opportunities of a Society of Longer Lives."

She and other speakers in "The American Society in 2035" symposium debunked myths, present research and discuss potential policy and societal solutions.

"This is a looming crisis," said Carstensen. "We will suffer many negative consequences if we don't apply science and technology to solve the problems of older people, rebuild the environments in which we live ? physical, societal and social ? and find ways to put this resource [older people] to use."

Revising social norms

Our culture is a starting point for change, said Carstensen. "The norms that tell us when to get an education, when to work, when to marry, when to retire evolved when life was half as long," she said.

"If we continue to abide by all of those norms, people will pack all of life basically into the first 65 years, and it will be too pressured," she said. "There will be too much to do. You're raising kids, reaching the peak of your career, taking care of aging parents, all at the same time.

"And then, bam! You have 30 years of leisure. That's a bad model, that's not working for anybody."

Money from 40 years of work can't fund 30 years of retirement.

Instead, Carstensen proposes to spread out work for more years, cut the number of working days per week and the hours worked per day, and integrate more sabbaticals into working schedules to give more time to other obligations.

"That will help governments [by alleviating] the strain on government programs to support people for decades longer than they were designed to do," she said. "And it will help individuals, because life can get easier and feel better."

Refocusing medicine

Sustaining the health of an aging population is an obvious issue. Carstensen identifies chronic, long-term diseases as a much bigger problem today than before. Most of the medical advances in the last century involved acute diseases that affected mainly young people, she said. There has been less progress on chronic diseases that inflict old people, like diabetes, arthritis and osteoporosis.

"Flash back 100 years, this wasn't a big problem," she said. "It wasn't a big problem for society or most individuals, because you were dead before you would get those diseases. But today, they are problems."

Redesigning the suburbs

As the country ages, our homes need to be redesigned, Carstensen said.

"The built environment that we live in today presumed a young population," she said. "A population of relatively young people, who raised families of four children, lived in the suburbs in a big house with three or four bedrooms and a yard, where you have to have a car.

"Today, you have a couple or a widow, in their 80s or 90s, their kids are gone," she said. "They're living in a house that's too big for them. It's not good for the environment, in terms of energy consumption. And if they get to a point where they can't drive, they're essentially isolated.

"We often like to say the problem is old people," Carstensen said. "The problem is the environment."

She suggests redesigning the suburbs by providing better public transportation, retrofitting sidewalks to be safer and adding benches. Increased mobility would give residents more opportunities to continue to work within society.

Rethinking roles for older people

The growing number of aging people are more capable in some respects than their younger counterparts, said Carstensen.

"We have presumed, even in science, that age is associated with decline," she said. "But it turns out that's not true. The profile for aging is much more nuanced. There is decline, but there are also improvements ? in emotional functioning, improvements in knowledge.

"If you have a large population of emotionally stable, knowledgeable and relatively healthy old people, that's a good resource."

One potential job would be to mentor younger generations. With millions of illiterate American children and an alarming number of failing high school students with busy or uneducated parents unable to help them, Carstensen envisions that the older and wiser can lend a hand.

"If we can channel the talents of older people into solving the problems of our educational system, we will win big," she said. "Hugely big, in the sense of the future of the country, and future scientists and engineers."

Stephen Tung is a science-writing intern at the Stanford News Service.

 

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New Roles for Increasing Percentage of Older Citizens in an Aging America

Study shows significant state-by-state differences in black, white life expectancy

Public release date: 24-Feb-2012
[ | E-mail | Share ]

Contact: Enrique Rivero
erivero@mednet.ucla.edu
310-794-2273
University of California - Los Angeles Health Sciences

A UCLA-led group of researchers tracing disparities in life expectancy between blacks and whites in the U.S. has found that white males live about seven years longer on average than African American men and that white women live more than five years longer than their black counterparts.

But when comparing life expectancy on a state-by-state basis, the researchers made a surprising discovery: In those states in which the disparities were smallest, the differences often were not the result of African Americans living longer but of whites dying younger than the national average. And, interestingly, the area with the largest disparities wasn't a state at all but the nation's capital, Washington D.C.

The findings are published in the February issue of the peer-reviewed journal Health Services Research.

"In health-disparities research, there is an assumption that large disparities are bad because vulnerable populations are not doing as well as they should, while areas with small disparities are doing a better job at health equity," said Dr. Nazleen Bharmal, the study's lead researcher and a clinical instructor in the division of general internal medicine and health services research at the David Geffen School of Medicine at UCLA. "In our study, we show that the reason there are small disparities in life expectancy is because white populations are doing as poorly as black populations, and the goal in these states should be to raise health equity for all groups."

The data on which the researchers relied included both health-related and non?health-related deaths, such as murder and accidents. The findings, however, still highlight the need to improve the health of the nation's African Americans, the researchers said.

The research team studied death-certificate data from the U.S. Multiple Cause of Death for the years 1997?. The data covered 17,834,236 individuals in all 50 states and the District of Columbia. The researchers noted race/ethnicity, sex, the age at death and the state where each subject was born, lived and died.

Overall, the national life expectancy was 74.79 years for white men and 67.66 years for black men. Among women, the average life span was 79.84 years for whites and 74.64 for blacks. In every state, gaps were narrower between women than men.

New Mexico had the smallest disparities between blacks and whites (3.76 years for men and 2.45 years for women), while the District of Columbia had the largest (13.77 years for men and 8.55 years for women).

States with the largest disparities

In addition to Washington, D.C., the states with the largest disparities between white and black men were New Jersey, Nebraska, Wisconsin, Michigan, Pennsylvania and Illinois; in these states, the gap was greater than eight years because African American men's lives were shorter than the national average for black men and white men's life spans were equal to or greater than the national average.

For women, the states with the largest disparities in longevity were Illinois, Rhode Island, Kansas, Michigan, New Jersey, Wisconsin, Minnesota, Iowa, Florida and Nebraska, where the difference between black and white women was more than six years. White women in these states lived longer than average, while black women had average or lower life expectancy.

States with the smallest disparities

In addition to New Mexico, which had the smallest disparities, eight other states had black?white disparities of less than six years among men: Kentucky, West Virginia, Nevada, Oklahoma, Washington, Colorado, New York and Arizona.

In four of these states ? Kentucky, West Virginia, Nevada and Oklahoma ? the smaller disparities were due to a combination of African American men living longer than the national average and whites having shorter lives. But in New Mexico, Washington, Colorado, New York and Arizona, both black and white men lived longer than average, with black men having life spans that were particularly longer than the national average.

Among women, the states with the smallest differences were New Mexico, New York, West Virginia, Kentucky and Alabama ? each with disparities of less than four years. These smaller disparities were the result of black women being longer-lived than average and whites being shorter-lived.

Fifty-eight percent of African Americans live in 10 states: New York, California, Texas, Florida, Georgia, Illinois, North Carolina, Maryland, Missouri and Louisiana. Eliminating the disparities in just these states, the researchers said, would bring the national disparity down substantially. For instance, eliminating the disparity in Florida alone would reduce the national disparity from 7.13 years to 6.63 years for men and from 5.20 years to 4.74 years for women.

Because disease prevention and health promotion efforts identify and monitor magnitudes in disparities, these findings could point to new ways that government agencies can track and measure differences in health outcomes, the authors write. Also, the researchers feel that these differences in life expectancy should be considered when funding health programs at local and national levels. Finally, they write, state governments should consider these differences in black?white longevity in formulating health policy, given that coverage through health programs such as Medicaid varies widely among states.

There are some limitations to the study. Among them, the researchers did not account for population changes during the years covered in their analysis, though, they said, it is doubtful such changes would alter the overall findings. Also, they did not consider the tendency of people to move from place to place, which could influence health. They also could not use data from 11 states, but those areas had such small numbers of African Americans that the estimates would not have been reliable.

Also, the study covered all causes of mortality, including murder and accidental deaths. Going forward, the researchers plan to investigate disparities in life expectancy by cause of death.

###

In addition to Dr. Nazleen Bharmal, researchers included Chi-Hong Tseng and Mitchell Wong of UCLA and Robert Kaplan of the National Institutes of Health.

Bharmal was funded by the Robert Wood Johnson Clinical Scholars Program and a National Research Service Award Fellowship at UCLA.

General Internal Medicine and Health Services Research is a division within the department of medicine at the David Geffen School of Medicine at UCLA. It provides a unique interactive environment for collaborative efforts between health services researchers and clinical experts with experience in evidence-based work. The division's 100-plus clinicians and researchers are engaged in a wide variety of projects that examine issues related to access to care, quality of care, health measurement, physician education, clinical ethics and doctor?patient communication. The division's researchers have close working relationships with economists, statisticians, social scientists and other specialists throughout UCLA and frequently collaborate with their counterparts at the RAND Corp. and Charles Drew University.

For more news, visit the UCLA Newsroom and follow us on Twitter.

[ | E-mail | Share ]

 

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

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Study shows significant state-by-state differences in black, white life expectancy

Rick Santorum: Live Longer with God [Dean's Corner]

Why has our life expectancy increased so much since the American Revolution?

According to Presidential candidate Rick Santorum: "Because God says they have rights."

What about the role of sanitation, nutrition, education, medicine?

This is an example of religious faith clashing with reason, with all due respect to those with faith.

From "Human Longevity: The Major Determining Factors" by Joseph A. Knight, M.D.:

Wealth, and an affluent environment, significantly correlate with life expectancy as shown by a marked increase in life expectancy over the past century due to the marked improvement in sanitation, nutrition, education and medicine.

And from American Scientist:

As early as 1840, life expectancy started increasing in Sweden. Soon, the trend appeared in other developed countries, too. In the United States, for example, white females in 1900 lived an average of 48 years; by 2000, they lived an average of 87 years. This 39- year increase in average lifespan really took hold by mid-century, largely due to reduced mortality before puberty, which killed 24 percent of the women born in 1900. Young girls-no longer taken by accidents or infectious diseases- survived to die as old ladies.

In the 1920s, extensive public- health measures, including sanitary sewers and clean drinking water, triggered this decreased mortality. Later, antibiotics and improved medical care increased average life spans even more. As the 20th century rolled by, the elderly grew more healthy and mentally independent than their parents at the same ages. In addition, the average person lived longer than ever. Consequently, the probability of some proportion of them surviving for more than a century increased, as well.

Follow this link:
Rick Santorum: Live Longer with God [Dean's Corner]

Kenneth Pelletier: Health and Your Whole Being (excerpt) – Thinking Allowed w/ Jeffrey Mishlove – Video

25-08-2010 09:26 NOTE: This is an excerpt from the full 90-minute DVD. http://www.thinkingallowed.com What constitutes a balanced lifestyle? How can diet, exercise and stress management combine to produce optimal states of health? Dr. Kenneth Pelletier, one of the world's foremost authorities on holistic lifestyle, notes that health of the whole being requires both individual responsibility and choice and proper support from the health care system. He then focuses on the details of developing a personal holistic health program. He addresses issues of nutrition, environmental factors, stress management, exercise and relaxation, strengthening the immune system and promoting longevity. Finally, he discusses the importance of spirituality and personal attunement with nature. Kenneth R. Pelletier, Ph.D., is a Clinical Professor of Medicine, Department of Medicine, at the University of Maryland School of Medicine and at the University of Arizona School of Medicine. At the University of Maryland, he is Director of the Corporate Health Improvement Program (CHIP) which is a collaborative research program between CHIP and 20 of the Fortune 500 corporations. He is author of Healthy People in Unhealthy Places, Longevity, Holistic Medicine and Mind As Healer--Mind As Slayer.

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Kenneth Pelletier: Health and Your Whole Being (excerpt) - Thinking Allowed w/ Jeffrey Mishlove - Video