Personalised medicine for all could be a possibility in the "very near future" as everybody will soon be able to have their entire DNA make-up mapped for as little as £100, a leading professor said.
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Everybody's DNA could be on genetic map in 'very near future'
By Caroline Arbanas - Our bodies contain far more microbial genes than human genes.
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"I think if we accidentally discover something we must tell them. ... I think we have an obligation to tell them." - Dr. Daniel Notterman Analyzing a person’s genetic makeup can produce a road map of disease the person is likely to encounter and possible paths for avoiding or defeating it.
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Inside each of us, in every cell, are potential answers to great mysteries. Our genes can offer insight into the seemingly innocuous: Why do I despise cilantro? Why are my ears so impossibly big? And they hold darker secrets: risks for sudden heart failure, diabetes, of fast-growing cancers and Alzheimer’s disease.
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Lawrence LeBlond for redOrbit.com - Your Universe Online Perfection is something that all humans strive for at one time or another, be it scoring a perfect 100 on a test, making the perfect soufflé, having the perfect play in basketball, or even landing the perfect job. For others, perfection is a state of well-being—as in being perfectly healthy. While achieving perfect health may be plausible ...
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Nobody Is Perfect: Study Shows People Have 400 Genetic Flaws In DNA
A new genetic test has resulted in remarkably more applicable information than the current routine of prenatal testing, suggests a new study published in The New England Journal of Medicine. The test uses microarray analysis to more effectively examine a fetus's DNA than is currently possible with the karyotyping method, a visual examination of the fetus's chromosomes. The blinded trial, led by ...
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( University of Texas Medical Branch at Galveston ) A new test for analyzing the chromosomes of stillborn babies, known as microarray analysis, has now proven 40 percent more effective in pinpointing potential genetic causes of death than the old karyotype testing procedure. Researchers at the University of Texas Medical Branch at Galveston, along with a team of other national leaders in ...
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New applications of a genetic test could help parents learn more about the genetics of their unborn children. read more
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Our bodies contain far more microbial genes than human genes. And a new study suggests that just as human DNA varies from person to person, so too does the massive collection of microbial DNA in the intestine. The research is the first to catalog the genetic variation of microbes that live in the gut.
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Advanced genetic tests performed before birth on a fetus can spot potential defects better than current prenatal tests and may help pinpoint abnormalities that cause stillbirths, researchers said.
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Precision medicine and cancer genetics were among the topics discussed during 11 breakout sessions guided by 30 UCSF faculty members at the Nov. 7 showcase for the UCSF Helen Diller Family Comprehensive Cancer Center.
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Cancer, Genetic Risks and Precision Medicine Highlighted at Showcase
Lawrence LeBlond for redOrbit.com - Your Universe Online Two new papers published in the New England Journal of Medicine ( NEJM ) show that genetic testing in early pregnancy reveals far more about potential birth defects and stillbirth risk than current prenatal testing does, based on a multi-center clinical trial using both methods. The clinical trials showed that 6 percent of certain fetuses ...
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Genetic Test Reveals More About Potential Birth Defects Than Conventional Methods
Fifteen new genetic regions associated with coronary artery disease have been identified by a large, international consortium of scientists -- taking a significant step forward in understanding the root causes of this deadly disease.
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Inflammation may be a cause of plaque buildup in heart vessels
( Stanford University Medical Center ) Fifteen new genetic regions associated with coronary artery disease have been identified by a large, international consortium of scientists -- including researchers at the Stanford University School of Medicine -- taking a significant step forward in understanding the root causes of this deadly disease.
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International study points to inflammation as a cause of plaque buildup in heart vessels
Nearly three-quarters of mutations in genes that code for proteins -- the workhorses of the cell -- occurred within the past 5,000 to 10,000 years, fairly recently in evolutionary terms, said a national consortium of genomic and genetic experts, including those at Baylor College of Medicine.
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An all-new edition of Genomic and Personalized Medicine promises to be a one-stop shop for doctors and other health professionals as they face the rapid growth of genetic and genomic testing in the clinic.
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New Book on Genome and Personalized Medicine Preps Doctors for Changing Reality
NEW YORK (GenomeWeb News) – A personalized molecular medicine company offering physicians access to clinically actionable genetic tests has been launched.
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CAMBRIDGE -- With personalized medicine becoming a key focus for medical research and diagnosing conditions, Partners HealthCare System, the region’s largest hospital and physicians network, is positioning itself to become a national leader in the emerging field.
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Public release date: 29-Nov-2012 [ | E-mail | Share ]
Contact: Lauren Woods Law2014@med.cornell.edu 646-317-7401 New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
NEW YORK (Nov. 29, 2012) -- Weill Cornell Medical College researchers Dr. Shahin Rafii and Dr. Xin-Yun Huang have been elected new Fellows of the American Association for the Advancement of Science (AAAS), the world's largest general scientific society, for their significant contributions to the advancement of the biological sciences.
Dr. Rafii, director of the Ansary Stem Cell Institute and the Arthur B. Belfer Professor in Genetic Medicine at Weill Cornell, is honored for his important contributions to the field of vascular biology, stem cell homeostasis and the development of transformative preclinical models to induce organ regeneration and target tumors. Dr. Huang, professor of physiology and biophysics at Weill Cornell, is recognized for his distinguished contributions in the field of cellular signaling, particularly his investigations of G-protein-mediated cell signaling.
"Dr. Rafii and Dr. Huang's research discoveries in cellular communication, stem cell research, cancer and vascular disease have led to major advancements in biomedical research and the development of targeted therapies," says Dr. Laurie H. Glimcher, the Stephen and Suzanne Weiss Dean of Weill Cornell Medical College, who is also a Fellow of AAAS. "Weill Cornell is very proud of the work of these two world-renowned innovators in medicine and their new membership in this prominent community of scientists dedicated to advancing science around the world."
This year, Dr. Rafii and Dr. Huang are among the 702 new Fellows awarded election to the AAAS for their scientifically or socially-distinguished efforts to advance science or its applications. This prestigious honor of AAAS election is bestowed by peer Fellows of AAAS.
Dr. Rafii and Dr. Huang will be presented with an official certificate and a gold and blue rosette pin, representing science and engineering, on Saturday, Feb. 16 at the AAAS Fellows Forum during the 2013 AAAS Annual Meeting in Boston, MA. Also, new AAAS Fellows will be announced in the AAAS' journal Science on Nov. 30.
Dr. Rafii, an internationally known vascular biologist, cancer and stem-cell authority, is also an investigator of Howard Hughes Medical Institute at Weill Cornell. Dr. Rafii's research explores innovative therapeutic frontiers for cancer and vascular disorders. His research focuses on the understanding of stem cell biology, as well as the means to develop and test innovative approaches to treat cancer and vascular disorders by exploring the therapeutic potential of human and embryonic stem cells and, most recently, amniotic-fluid derived cells for treatment of human malignancies, vascular diseases and genetic disorders. His work has paved the way for stem-cell therapy for the treatment of vascular insufficiencies. Dr. Rafii received his undergraduate degree in chemistry from Cornell University and his medical degree from Albert Einstein College of Medicine. He has been funded by multiple grants from the National Institute of Health's Heart, Lung and Blood Institute, and is an active member of the Tumor Microenvironment Study Section at the National Cancer Institute. He is an elected member of the American Society of Clinical Investigation, an American Cancer Society Scholar and a Translational Researcher of the Leukemia & Lymphoma Society.
Dr. Huang's research focuses on G protein-coupled receptors and G proteins that are key cell signaling molecules with the ability to control and disseminate information flow. G protein-coupled receptors represent approximately 40 percent of the current drug targets. These receptors are activated by a diverse array of ligands, including photons, odorants, chemokines, hormones, growth factors and neurotransmitters. The GPCR-G protein signaling system plays critical roles in various physiological functions such as cardiovascular and neurological functions, and in human diseases such as cancer. Dr. Huang examines signal transduction using biochemical, genetic, molecular, cellular and structural biological approaches to uncover fundamental mechanisms that govern cellular signaling and physiological functions. His team inspects cross-talk between G proteins and nonreceptor tyrosine kinases, two of the most widely used cellular signaling mechanisms. Dr. Huang explores the activation mechanisms of G proteins by G protein-coupled receptors, the regulatory mechanisms of endothelial cell migration, blood vessel formation and tumor angiogenesis by G proteins, as well as the control mechanisms for actin cytoskeletal reorganization, cell migration and tumor metastasis. Dr. Huang completed his undergraduate studies at Wuhan University in China, received his Ph.D. from the University of Houston and his postdoctoral research training at Columbia University and Harvard University.
The AAAS Fellows tradition began in 1874. Currently, members can be considered for the rank of Fellow if nominated by the steering groups of the Association's 24 sections, or by any three Fellows who are current AAAS members, or by the AAAS chief executive officer. Each steering group then reviews the nominations of individuals within its respective section and a final list is forwarded to the AAAS Council, which votes on the aggregate list. The Council is the policymaking body of the Association, chaired by the AAAS president, and consisting of the members of the board of directors, the retiring section chairs, delegates from each electorate and each regional division and two delegates from the National Association of Academies of Science.
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Lone Frank, on a mission to discover what makes an identity, decides that her genes are not necessarily her fate Lone Frank is self-obsessed, in a generous way. She is on a mission to discover what makes an identity, a life trajectory, a career choice, a social animal. There is just one identity she can describe without fear of contradiction. The key is her genome. So think of her as a pioneer ...
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My Beautiful Genome: exposing our genetic future, one quirk at a time – review