Biotechnology: Things you should know about Gene Therapy

Introduction

Genetic disorders are becoming common nowadays due to stressful modern lifestyle. Latest technologies are the added values to create many genetic disorders. To overcome the disorders, Gene therapy is a blessing. In order to compensate abnormal genes and make a good gene, genetic material is introduced into cells. In this way, mutated gene will act as a normal gene. Let us see in detail.

Ways to insert the gene

There are indirect ways need to be followed to make a gene to function as if it is inserted directly does not function. Carrier also called as vector is used to deliver the gene. In the place of vectors, virus play the role as they are getting modified and hence people are not affected with new diseases when it is integrated into the chromosome of the human cell.

The vectors need to get injected to specific tissue in the body or outwardly patient’s cell is removed and exposed to the vector. In either of the ways need to be again returned to the patient. Successful treatment makes proper genes and genetic disorders get solved.

Gene therapy for treating cancer

Cancer is the dangerous disease and there are many ways to cure cancer including surgery, chemotherapy, and radiation. But cancerous cells in due course again spread and hence it is a deadly disease. Gene therapy is the best way discovered nowadays for treating cancer.
Let us see the basic fundamentals of cells. cells include packets of data in genes, created either from DNA or RNA. Sequence is there for DNA and if it is in the order, there will be no problem. But at the same time If there is disorder occurs in portion of the genes either turning or changing the position, cells lost their control and abnormal growth is seen which result in cancerous tumors. It can spread in mouth, breast, lung etc.,

Specialists in Gene therapy analyze the patient’s criticality first and follow the treatment procedures. One way is they replace missing or mutated genes into wholesome genes. Inserting totally new genes for fighting cancer, placing DNA into cancerous cells to undergo chemotherapy and radiation or injecting bad gene to destroy them etc., Mesothelioma type of cancers are not at all responded in formal therapies and hence one need to undergo gene therapy essentially. Need to have consultations with doctors to overcome their deadly disease.

Gene therapy importance

Doctors decide whether gene therapy is suitable by the following approaches. If genetic disorders are from mutations in one or more genes or whether a normal copy of the gene that is available in the patient is enough to fix the problems in the affected cells, then doctors determine that gene therapy will be more helpful rather than going for traditional methods.

Conclusion

Genetic engineering is a vast topic. Latest Science innovations in the field of genetic engineering yields for gene therapy. Doctors and scientists together working to find out whether gene therapy is the best suitable way for treating deadly diseases like cancer and others. Let us salute for the positive force of gene therapy.

 

Source:
http://www.biotechblog.org/entry/biotechnology-gene-therapy/

Biodiscovery and what a fish can see – Video


Biodiscovery and what a fish can see
Biodiscovery is the science of collecting organic structures from the natural environment. These natural specimens collected from coral reefs and sponges have evolved over millions of years and provide scientists with unimaginable chemical structures that are later made into medical and technological products. For example sunscreens, cures to disease even possibly cures to cancers. This video covers biodiscovery, biotechnology and even how scientists are now able to looking at how fish sense their environment through the perspective of a fish.From:Trevor DominicViews:0 0ratingsTime:04:24More inScience Technology

Excerpt from:
Biodiscovery and what a fish can see - Video

Ribbon "lifting" for 100000th cross display at IRRI – Video


Ribbon "lifting" for 100000th cross display at IRRI
Also see: http://www.youtube.com On 29 November 2012, the community at the International Rice Research Institute (IRRI; irri.org) celebrated the 100000th rice breeding cross, a true milestone in the Institute #39;s 52-year history existence. The parents for the 100000th cross were IR09M105 and NSICRC 214.The objective of this particular cross was to improve eating quality. In this clip, Bas Bouman (left), director of the Global Rice Science Partnership (GRiSP) and Bruce Tolentino, deputy director general for communications and partnerships, "lift" the ribbon at the display showing the mature plants resulting from the cross along with the parents in the background. Glenn Gregorio, senior scientist in Plant Breeding, Genetics, and Biotechnology (PBGB) at IRRI, is the MC wrapped in the ribbon by Dr. Bouman at the conclusion. Special guest at the event was Rizal M. Herrera, who was among the first breeders to make crosses at IRRI in the early 1960s - http - Mr. Herrera arrived at IRRI in 1961 as a research aide and retired 36 years later in 1997 as a senior assistant scientist. Below is his poem-essay about how, in rice breeding, marriage respects no boundaries. Marriage Respects No Boundaries by Rizal M. Herrera IRRI rice breeder, 1961-97 Innocent-looking rice plants also engage in courtship and marriage practices. The rites are simple, devoid of elegant, expensive entourage, and there are no high government officials in flashy cars acting as principal sponsors. The bride, the ...From:irrivideoViews:64 3ratingsTime:02:29More inEducation

Read more:
Ribbon "lifting" for 100000th cross display at IRRI - Video

Life Un(Ltd), Charis Thompson, Three Times a Woman- A Gendered Economy of Stem Cell Innovation Pt. 2 – Video


Life Un(Ltd), Charis Thompson, Three Times a Woman- A Gendered Economy of Stem Cell Innovation Pt. 2
This presentation was part of CSW #39;s Life (Un)Ltd project, and took place on October 24, 2012. Life (UnLtd) is an interdisciplinary project initiated by CSW Associate Director Rachel Lee that engages recent developments in biosciences and biotechnology, foregrounding critical, aesthetic, and ethics-based approaches to what have become global research and marketing industries.From:UCLAViews:6 0ratingsTime:36:53More inEducation

Read this article:
Life Un(Ltd), Charis Thompson, Three Times a Woman- A Gendered Economy of Stem Cell Innovation Pt. 2 - Video

2012 Interview with Joe Bouton, Ph.D. – Video


2012 Interview with Joe Bouton, Ph.D.
After an association that began in the mid-1990s, Dr. Joe Bouton retired from the Samuel Roberts Noble Foundation in December 2012. In late October 2012, Bouton sat for an interview in which he reviewed his time with the Noble Foundation and looked to the future of the Forage Improvement Division and the organization #39;s forage breeding program. During his tenure at the Noble Foundation, Bouton served as a non-resident fellow, acting head of the Forage Biotechnology Group, director of the Forage Improvement Division, senior vice president and senior professor. Before coming to the Noble Foundation as director of the Forage Improvement Division, Bouton had a successful career at the University of Georgia at Athens. His forage breeding work has resulted in the release of many commercialized cultivars that are important to farmers and ranchers in the Southern Great Plains and across the southeastern United States.From:thenoblefoundationViews:9 0ratingsTime:05:30More inEducation

Read more here:
2012 Interview with Joe Bouton, Ph.D. - Video

Life UnLtd, Charis Thompson, Three Times a Woman A Gendered Economy of Stem Cell Innovation Pt 1 – Video


Life UnLtd, Charis Thompson, Three Times a Woman A Gendered Economy of Stem Cell Innovation Pt 1
This presentation was part of CSW #39;s Life (Un)Ltd project, and took place on October 24, 2012. Life (UnLtd) is an interdisciplinary project initiated by CSW Associate Director Rachel Lee that engages recent developments in biosciences and biotechnology, foregrounding critical, aesthetic, and ethics-based approaches to what have become global research and marketing industries.From:UCLAViews:6 0ratingsTime:27:24More inEducation

Original post:
Life UnLtd, Charis Thompson, Three Times a Woman A Gendered Economy of Stem Cell Innovation Pt 1 - Video

Passfail.com News: Tuesday Sector Leaders: Music


Passfail.com News: Tuesday Sector Leaders: Music Electronics Stores, Biotechno...
In trading on Tuesday, music electronics stores shares were relative leaders, up on the day by about 1.7%. Leading the group were shares of Radioshack (RSH), up about 5.1% and shares of Best Buy (BBY) up about 2.4% on the day. Also showing relative strength are biotechnology shares, up on the day by about 1.7% as a group, led by Acadia Pharmaceuticals (ACAD), trading higher by about 138.3% and Peregrine Pharmaceuticals (PPHM), trading higher by about 17.9% on Tuesday. This is Sayoko Murase for Passfail.com, taking you behind the ticker. For Passfail.com, Behind The Ticker (TM) Pass Fail NewsFrom:passfailtvViews:0 0ratingsTime:00:45More inNews Politics

Visit link:
Passfail.com News: Tuesday Sector Leaders: Music

Mario Ottiglio of IFPMA on WHO R


Mario Ottiglio of IFPMA on WHO R D financing and treaty negotiations
Interview with Mario Ottiglio, Associate Director, Public Affairs Global Health Policy for the International Federation of Pharmaceutical Manufacturers and Associations (IFPMA). IFPMA is a Geneva based trade organization that represents the research-based pharmaceutical industry, including the biotechnology and vaccine sectors. Mario was interviewed by KEI on November 26, 2012, about the WHO negotiations on a medical R D treaty.From:KEIWashDCViews:4 0ratingsTime:01:48More inScience Technology

View post:
Mario Ottiglio of IFPMA on WHO R

NCSU MB 351 Presentation: Food Spoilage! – Video


NCSU MB 351 Presentation: Food Spoilage!
References: Alfaro, Danilo. "Food Poisoning and Food Spoilage." Culinary Arts. About.com, nd Web. 19 Sept. 2012. culinaryarts.about.com Bailey, Regina. "Bacteria and Food Poisoning." Biology. About.com, nd Web. 19 Sept. 2012. biology.about.com Blackburn, Clive De W, ed. Food Spoilage Microorganisms. Woodhead Publishing, 2006. Knovel. Web. 19 Sept. 2012. http://www.knovel.com Edublogs.org. "Beano Lab." Brebeuf Jesuit Biotechnology, 2012. Web. 30 Oct. 2012. bjpsbiotech.edublogs.org Eye Of Science. "Bacillus Coagulans, SEM." Science Photo Library. Np, nd Web. 30 Oct. 2012. http://www.sciencephoto.com Fischer, Peter. "Molding Bread as a Natural Clock." The Age Of The Earth And The Formation Of The Universe. Timothy H. Heaton, 2005. Web. 30 Oct. 2012. orgs.usd.edu "Food Contamination and Spoilage." Hygiene And Environmental Health HEAT Module. LabSpace, nd Web. 19 Sept. 2012. labspace.open.ac.uk "Food Spoilage and Additives." Biotopics.co.uk, nd Web. 6 Oct. 2012. http://www.biotopics.co.uk "Hardychrom Candida." Hardy Diagnostics. Hugo: Hardy User Group Observer, 1996. Web. 30 Oct. 2012. catalog.hardydiagnostics.com "Kenya Could Save Millions of Shillings If It Can Make Use of a Fungus Which Reduces Aflatoxins in Cereal Crops."Organic Farmer Magazine. The Organic Farmer, Sept. 2010. Web. http://www.organicfarmermagazine.org Mouldy Foods, Cheese, Bread, and Fruit." Science Photo Library. Science Photo, nd Web. 30 http://www.sciencephoto.com "Preservation of Foods." Army Medical. Integrated Publishing, nd Web. 19 ...From:Katherine BarefootViews:0 0ratingsTime:09:40More inEducation

Read more here:
NCSU MB 351 Presentation: Food Spoilage! - Video

ECOLife Expo 2012: Jing Liu (Lund University) talks about AMPTS and biogas power – Video


ECOLife Expo 2012: Jing Liu (Lund University) talks about AMPTS and biogas power
ECOLife Expo 2012: Jing Liu (Lund University) talks about AMPTS and biogas power Jing Liu, Ph.D, Associate Professor at the Department of Biotechnology of Lund University, talks about the present of biogas power, introducing AMPTS.From:nicklandtubeViews:0 1ratingsTime:02:03More inScience Technology

Read the rest here:
ECOLife Expo 2012: Jing Liu (Lund University) talks about AMPTS and biogas power - Video

Let’s Play Deus Ex: Human Revolution Ep. 3 – Video


Let #39;s Play Deus Ex: Human Revolution Ep. 3
(Mature)(Casual)(Commentary) Cyberpunk with me. The game is set in 2027, 25 years before the first game in the series, at a time when multinational corporations have grown in power beyond the control of national governments. The game follows Adam Jensen, the newly hired security director at Sarif Industries, a growing biotechnology firm. After terrorists brutally attack Sarif #39;s Detroit-based headquarters, the mortally wounded Jensen is forced to undergo radical life-saving surgeries that replace large areas of his body with advanced prostheses. Returning to work, he becomes embroiled in the global politics of the human enhancement movement in the search for those responsible for the attack. A central theme to the game is the rise of corporations in globalization, espionage, human survival, poverty and the ethics of advancing humans with artificial replacements for body parts. playlist - http://www.youtube.comFrom:AngryjollyViews:0 0ratingsTime:22:17More inGaming

Read this article:
Let's Play Deus Ex: Human Revolution Ep. 3 - Video

Therapeutic Uses of Disaccharides presentation – Video


Therapeutic Uses of Disaccharides presentation
A presentation in Therapeutic Uses of Disaccharides presented by a team of Veterinary Medicine second year students, Cairo University (2012-2013). Narrated by Salma Waheed Abdelhaleem. References: Wikipedia, McGraw Hill, hartONline, designidentity, wise, Howard Hughes medical institute, Harvard School of Public Health, BBC news, world health organization, edentvproject, Pearson education Inc, Medicomdigital, Epinex diagnostics Inc, discovery health channel, Your Practice Online, 3D Medical Animation Library, Dr. RUFUS #39; Medical website, Ucyclyd Pharma, Mechanisms in Medicine, visiblebody, MAYO Clinic, Cancer treatment centers of America, National Center for Biotechnology Information (NCBI), National Cancer InstituteFrom:SalmaWaheedViews:1 0ratingsTime:28:02More inEducation

Read the original here:
Therapeutic Uses of Disaccharides presentation - Video

Extracting DNA – Video


Extracting DNA
Get the best offer here redirect.viglink.com?key=f341fd9454fc162be8b38d504acbd4e1 out=http%3A%2F%2Fwww%2Eamazon%2Ecom%2Fdp%2FB005CIRCL0 Product Description Extracting DNA DNA has often been called "the building block of life". Therefore, the extraction of this key biological material, which is the first step in its analysis and manipulation, is of primary importance to the field of biotechnology. Your students will use a simple and quick method to isolate DNA and observe its physical characteristics using a variety of sources. Grades 7-10.From:Zelda PointerViews:0 0ratingsTime:00:56More inSports

Excerpt from:
Extracting DNA - Video

Deus Ex: Human Revolution – Gameplay [First mission] – Video


Deus Ex: Human Revolution - Gameplay [First mission]
Deus Ex: Human Revolution is a cyberpunk-themed action role-playing video game developed by Eidos Montreal and published by Square Enix, which also produced the game #39;s CGI sequences. Released in August 2011, it is the third game in the Deus Ex series, and a prequel to the original game released in 2000.[13] The Mac OS X version of the game, an "Ultimate Edition" which also contains The Missing Link downloadable content, is published by Feral Interactive and was released on April 26, 2012.[3] The game is set in 2027, 25 years before the first game in the series, at a time when multinational corporations have grown in power beyond the control of national governments. The game follows Adam Jensen, the newly hired security director at Sarif Industries, a growing biotechnology firm. After terrorists brutally attack Sarif #39;s Detroit-based headquarters, the mortally wounded Jensen is forced to undergo radical life-saving surgeries that replace large areas of his body with advanced prostheses. Returning to work, he becomes embroiled in the global politics of the human enhancement movement in the search for those responsible for the attack. A central theme to the game is the rise of corporations in globalization, espionage, human survival, poverty and the ethics of advancing humans with artificial replacements for body parts. Human Revolution received critical acclaim upon its release, with many reviewers praising the open-ended nature of the game and the weight of social ...From:TheManCowBearViews:1 0ratingsTime:34:43More inGaming

Read more:
Deus Ex: Human Revolution - Gameplay [First mission] - Video

Paques Brasil officially opened by Princess Máxima – Video


Paques Brasil officially opened by Princess Máxima
On the 21st of November 2012, Her Royal Highness Princess Máxima of the Netherlands inaugurated Paques Brasil Sistemas para Tratamento de Efluentes Ltda in Piracicaba, Brazil. Princess Máxima performed the official opening ceremony in the presence of the Minister for Foreign Trade and Development Cooperation, Ms. Lilianne Ploumen and the Dutch ambassador in Brazil, Mr. Kees Rade. Afterwards, the Princess was given a tour in the new manufacturing facilities and got informed about the Paques biological treatment technologies for wastewater and gas. The Prince of Orange and Princess Máxima are visiting Brazil from 19th to 23rd of November. This visit coincides with the economic mission of the Dutch Ministry of Foreign Affairs, which aims at strengthening economic ties with Brazil, including in the field of Bio-based Economy. The new subsidiary Paques Brasil is the third sales/production site of the Dutch company Paques, which in the last decades has specialized in the purification of water and gas based on biotechnology. With these technologies Paques has proven to be able to help companies and governments to meet one of the greatest challenges of our contemporary society: reducing the water and CO2 footprint and recovering valuable resources from waste (water). Paques #39; technologies are applied in various sectors all over the world.From:PaquesTVViews:0 0ratingsTime:02:03More inScience Technology

See the original post:
Paques Brasil officially opened by Princess Máxima - Video

Reaction wood — a key cause of variation in cell wall recalcitrance in willow

Background:
The recalcitrance of lignocellulosic cell wall biomass to deconstruction varies greatly in angiosperms, yet the source of this variation remains unclear. Here, in eight genotypes of short rotation coppice willow (Salix sp.) variability of the reaction wood (RW) response and the impact of this variation on cell wall recalcitrance to enzymatic saccharification was considered.
Results:
A pot trial was designed to test if the 'RW response' varies between willow genotypes and contributes to the differences observed in cell wall recalcitrance to enzymatic saccharification in field-grown trees. Biomass composition was measured via wet chemistry and used with glucose release yields from enzymatic saccharification to determine cell wall recalcitrance. The levels of glucose release found for pot-grown control trees showed no significant correlation with glucose release from mature field-grown trees. However, when a RW phenotype was induced in pot-grown trees, glucose release was strongly correlated with that for mature field-grown trees. Field studies revealed a 5-fold increase in glucose release from a genotype grown at a site exposed to high wind speeds (a potentially high RW inducing environment) when compared with the same genotype grown at a more sheltered site.
Conclusions:
Our findings provide evidence for a new concept concerning variation in the recalcitrance to enzymatic hydrolysis of the stem biomass of different, field-grown willow genotypes (and potentially other angiosperms). Specifically, that genotypic differences in the ability to produce a response to RW inducing conditions (a 'RW response') indicate that this RW response is a primary determinant of the variation observed in cell wall glucan accessibility. The identification of the importance of this RW response trait in willows, is likely to be valuable in selective breeding strategies in willow (and other angiosperm) biofuel crops and, with further work to dissect the nature of RW variation, could provide novel targets for genetic modification for improved biofuel feedstocks.Source:
http://www.biotechnologyforbiofuels.com/content/5/1/83

Mp3 Spiderworks – Shiver – Video


Mp3 Spiderworks - Shiver
ll4.me Mp3 Spiderworks - Shiver A highly atmospheric album soaked by an intense psychedelia. 6 MP3 Songs ROCK: Psychedelic, ROCK: Progressive Rock Details: Spiderworks is a heavy experimental rock band from Riverside, California that has existed off and on since 1988. The band was founded by Chris Vigil (vocals) and Monte Williams (bass), two central figures in the hardcore underground art and music scene in Riverside. Vigil and Williams later recruited Dan Hill (drums), Joe Hill (guitar), and Mike McKinnon (guitar); this lineup has remained intact. Spiderworks made their debut as an aggressive metal-tinged hardcore punk band, but soon morphed into an experimental punk-metal project heavily influenced by bands such as Voivod, Celtic Frost, Iron Maiden, Black Flag, and The Melvins. After releasing a cassette EP, Spiderworks were signed to the fledgling Alchemy Records label. The band recorded their debut "Black" album, but became entangled in a dispute with the label, which folded soon after. Left without a record contract, Spiderworks released the album independently around 1990. The album represented a musical evolution of sorts and featured a much more technically precise form of thrash/metal/punk. Lyrically the album was loosely conceptual, exploring the ambiguities of corporate biotechnology, urban expansion, and religious thought. The album was moderately successful and helped build a strong following for the band. By the end of 1990, Spiderworks began a string of ...From:michaelwyant9865Views:1 0ratingsTime:00:12More inPeople Blogs

See the original post:
Mp3 Spiderworks - Shiver - Video

Methane production by treating vinasses from hydrous ethanol using a modified UASB reactor

Background:
A modified laboratory-scale upflow anaerobic sludge blanket (UASB) reactor was used to obtain methane by treating hydrous ethanol vinasse. Vinasses or stillage are waste materials with high organic loads, and a complex composition resulting from the process of alcohol distillation. They must initially be treated with anaerobic processes due to their high organic loads. Vinasses can be considered multipurpose waste for energy recovery and once treated they can be used in agriculture without the risk of polluting soil, underground water or crops. In this sense, treatment of vinasse combines the elimination of organic waste with the formation of methane. Biogas is considered as a promising renewable energy source. The aim of this study was to determine the optimum organic loading rate for operating a modified UASB reactor to treat vinasse generated in the production of hydrous ethanol from sugar cane molasses.
Results:
The study showed that chemical oxygen demand (COD) removal efficiency was 69% at an optimum organic loading rate (OLR) of 17.05 kg COD/m3-day, achieving a methane yield of 0.263 m3/kg CODadded and a biogas methane content of 84%. During this stage, effluent characterization presented lower values than the vinasse, except for potassium, sulfide and ammonia nitrogen. On the other hand, primers used to amplify the 16S-rDNA genes for the domains Archaea and Bacteria showed the presence of microorganisms which favor methane production at the optimum organic loading rate.
Conclusions:
The modified UASB reactor proposed in this study provided a successful treatment of the vinasse obtained from hydrous ethanol production.Methanogen groups (Methanobacteriales and Methanosarcinales) detected by PCR during operational optimum OLR of the modified UASB reactor, favored methane production.Source:
http://www.biotechnologyforbiofuels.com/content/5/1/82

World-leading Cancer Researcher Professor Paul Workman Joins The Innovation Debate 2012 – Video


World-leading Cancer Researcher Professor Paul Workman Joins The Innovation Debate 2012
To watch the debate live register FREE today at http://www.innovationdebate.com Professor Paul Workman, Deputy Chief Executive and head of cancer therapeutics at The Institute of Cancer Research, London, will join the distinguished panel of world-leading experts and chairman Professor Jim Al-Khalili for The Innovation Debate 2012, taking place on 20th November at 4pm at the Royal Society in London and webcast live at http Together they will debate "How do we innovate in a time of austerity?" and "Are we doing enough to nurture innovators of the future?" Presenting his views on the current state of innovation, Professor Workman - who has also been a scientific founder of two successful biotechnology companies - said: "We are facing a serious challenge to the whole cancer drug discovery and development #39;ecosystem #39;. "We are making real progress but nowhere near as much as we could be in converting the incredible increase in our understanding of how cancer develops - especially our knowledge of the genomes of cancer cells - into new targeted therapies for cancer patients. "There is also a major challenge to the pharmaceutical industry in switching from the previous one-size-fits-all blockbuster model to the new future, which will be all about personalised medicines targeted to multiple small patient groups based on cancer genes. "At The Innovation Debate, I will discuss the important changes needed to address these challenges and to realise the full potential of cancer research for ...From:InnovationdebateViews:3236 1ratingsTime:02:18More inPeople Blogs

See more here:
World-leading Cancer Researcher Professor Paul Workman Joins The Innovation Debate 2012 - Video