Is Cameron Diazs clean wine as revolutionary as she thinks? – The Irish Times

Cameron Diaz gives a happy sigh. Im really excited, she says to her friend Katherine Power. On the table are two bottles of their new wine, Avaline, launched just last month.We were mad for a while, Diaz adds. You were a little bit more mad than I was. You had some real anger.

Anger? About wine?

When Diaz and Power decided to make their own wine, they discovered theres more to it than fermented grape juice. No transparency, no labelling, says Power, so shocked by what she found thatshe threw out all her wine.

The pair, speaking on Instagram, say they became determined to make a clean, chemical-free wine and are now, according to their publicist, on a mission to bring transparency to the wine industry.

Theyre not the only ones. Out of nowhere has come Good Clean Wine, which pairs with a healthy lifestyle; the Wonderful Wine Company, which offers wellness without deprivation; and Scout & Cellar, a multilevel-marketing company that boasts of its clean-crafted wine and intends to disrupt the wine industry and do better for the planet, among others.

Dr Creina Stockley sighs when she hears this over Zoom. Ive been in the industry for close to 30 years, and this comes up periodically, just under different names minimal intervention is one she remembers.Its a marketing exercise.

A pharmacologist and lecturer at the University of Adelaide, Stockley is a world authority on wine additives and processing aids, the heart of this issue.

Unlike the food industry, winemakers dont have to list ingredients. This has opened a door for opportunists, who profit by claiming that other wineries fill their wines with noxious chemicals (they dont).

The clean-wine companies are chasing a lucrative prize a piece of the 45 billionwellness market. A Scout & Cellar recruitment video notes that 68 per cent of consumers will pay more for products if theyre free of ingredients perceived as bad; disparaging the competition is good marketing. Its also working; the company reportedly made 16 millionin 2018, its first year.

Strangely, for companies committed to ripping the lid off the wine industry, the clean-wine gang is pretty quiet about where their own wines come from, and most declined to be interviewed. Where many wineries love giving encyclopaedic detail about the hill where their grapes are grown, for example, the Wonderful Wine Company simply says its white comes from France.

People are very interested in origin stories, says Brian Smith, chief executive of Winc Wines, which launched the Wonderful Wine Co in May, but the modern consumer is looking for, How does this fit into my life?

Winc Wines, which Smith founded with Geoff McFarlane, is one of the United Statesmost sophisticated online direct-wine businesses. Asked how Wonderful Wines offer wellness without deprivation, Smith says they use organic grapes wherever possible and dont manipulate their wines.

Which is an interesting claim, because wine doesnt make itself. If you drop Vitis vinifera grapes in a tub and leave them, they ferment, but what youll get is vinegar or cloudy, sour wine. Winemaking is both art and science, and, over centuries, winemakers have learned to prevent taints and spoilage, from using sulphur dioxide as an antibacterial and antioxidantto dropping egg whites into the wine to remove harsh-tasting tannins, a process known as fining.

Yet only 40 years agoa wine could be good one year and horrible the next. Since thenan explosion of microbiology, chemistry and viticulture research has driven a quality revolution.

Todays winemakers have an array of yeasts, antimicrobials and fining agents to choose from. Some function as ingredients that go into the wine, like extra acidity to perk up grapes from warm regions. Others are processing aids, mostly used to take things out of the wine.

Some have terrifying names, like polyvinylpolypyrrolidone (or PVPP, for short), but its the same binding agent found in aspirin tablets. Its sometimes used to reduce colour, to achieve pale pink ross. Such aids are legally defined and heavily regulated, and they dont stay in the wine.

But all this research has also allowed commercial winemakers to create bland, homogeneous wines that taste the same each year, regardless of vintage variation. In the US, some mass-market red wines have grape concentrate added the best known of which is Mega Purple to give extra colour and sweetness. Its illegal to add concentrate in the EU, where nothing can be added that changes the essential nature of a wine.

Many wine lovers are appalled by such practices, which render terroir the origin, or sense of place redundant.The backlash has led to a new category: natural wines. These are made by the nothing added, nothing taken away principle, usually from organic grapes.

But between natural and mass-market wines lies a vast and varied world. Just because winemaking tools exist doesnt mean people use them wineries dont spend money on things they dont need, and artisanal winemakers, in particular, pride themselves on their hands-off approach.

Stockley says, in any case, that modern wine needs less intervention than in the past, partly because winemakers have learned to make things smarter and better, but mostly because of improved grape growing. Some winemaking aids are no longer permitted; until 1997, animal blood could be used for fining. Ferrocyanide, which Scout & Cellar claims is a common additive in commercial wines, was a processing aid thats no longer legal.

So why not list ingredients? Dr Ignacio Snchez Recarte, secretary general of the Comit Europen des Entreprises Vins, which represents the EUs wine sector, says its because wine isnt made by an industrial process. While, say, a commercial bakery works to a strict, unchanging recipe, winemaking decisions change each vintage. Asking a small winery to update labels every year would impose an economic burden.

If you have anything in the wine with potential allergenic effects, you are obliged to indicate that on the label, however, and he adds that the wine sector understands modern consumers want transparency. Legislative change is under way in the EU.

I expect that by the end of 2022 there will be labels on wine, he says, adding that they will be either traditional labels or elabels. They will list ingredients, not processing aids nor will they show if the producer used pesticides.

Now youre opening up a can of worms, says Jamie Goode PhD, wine writer and author of wine textbooks. You cant grow grapes from Vitis vinifera without spraying eight to 14 times a year. The problem is mildew and then, at the end of the growing season, rot.

One of wines paradoxes is that the most prized, expensive grapes come from regions prone to fungal diseases, which can only be treated with commercial pesticides or, for organic growers, applications of copper sulphate.

Its all about the concentration, says Goode, adding: There are strict regulations concerning their use and concerning residue levels that are permitted. Wine is one of the most regulated and safe products there is.

Promising ultraviolet-light therapies are being trialled that may eliminate pesticides forever, but, for the moment, there is another potential way to avoid them. Its to farm in drier, warmer areas with less disease pressure, like Languedoc, in southern France birthplace of the Wonderful Wines white.

There are plenty of warm regions producing grapes at lower cost. California also has a grape glut right now, and theres more wine in tanks than many wineries know what to do with. Some use the best for themselves, then quietly sell the rest to whats known as the bulk wine market, where everything from commodity grapes to certified organic wines are sold.

Wineries also use their excess to make on-demand wines for buyers. In a twist, these exclusive wines often come from big wineries; despite being thoroughly conventional, they can even be marketed as minimal intervention or clean, because these are meaningless terms.

< p>Its a type of wine known as private label, which can be highly profitable because the seller doesnt have vineyards or wineries to maintain. Most winemakers talk obsessively about their land and heritage (try and stop them), so if these details are missing or vague, the wine could be private label, although some mass-market brands also omit this information.

Diaz and Powers Avaline, for example, is silent on who makes it. Then theres Scout & Cellars $25 (21) Gallivant chardonnay, whose web copy says its made by a fifth-generation family winery founded in Monterey in 1883, but not which one. In contrast, consider the $18 (15) Wente Vineyards Morning Fog chardonnay, which has a downloadable technical sheet explaining the region, soils and winemaking. Coincidentally, its also made by a fifth-generation family winery founded in 1883 in Monterey.

Unfortunately, all wine, however its made, contains a dangerous chemical: alcohol. No matter how sustainably the grapes are grown nor how consciously its made, there is no wine that wont deliver a hangover if you drink too much.

Wine is not a wellness potion. Its a snapshot of time, a manifestation of the place and the people who made it, which works a special magic when paired with friends and food.

When it comes to clean wine, the only thing being cleaned is your wallet. Guardian

Felicity Carter is editor-in-chief of Meiningers Wine Business International magazine

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Is Cameron Diazs clean wine as revolutionary as she thinks? - The Irish Times

What happens when bacteria resist treatment? Trobix lands $3M to protect us from next ‘Super Bug’ – Geektime

Trobix Innovation Ltd. an Israeli-based biotechnology company developing therapies to remove the threat of antimicrobial resistance, announces the closing of a $3 million Series A funding led by its lead investor, Chartered Opus. The funding will be used to advance the company's antimicrobial resistance platform technology and to further the pre-clinical development of its lead product, TBX101, which aims to treat patients carrying gut antimicrobial-resistant bacteria, resulting in antibiotic sensitive gut microbiome.

"I am grateful to Chartered Opus for their confidence in our technology and their trust in our team", said Dr. Adi Elkeles, Founder & CEO of Trobix Bio, which was founded in 2018. "Antimicrobial-resistant threatens to undermine the achievements of modern medicine, and Trobix Bio is committed to developing products that can effectively tackle this imminent threat", he added.

Antimicrobial resistance is a big issue, especially following the outbreak of the COVID-19 pandemic. According to the World Health Organization (WHO), microorganisms such as bacteria, fungi, viruses, and others develop a resistance once introduced to antimicrobial drugs like antibiotics. In light of the Coronavirus, effective treatments become a must, as they affect treatments that become ineffective, further allowing viruses to spread or diseases to take over.

Without a clear solution for the microbial resistance, the BioTech world continues to witness medical procedures such as organ transplants, cancer chemotherapy, diabetes management and major surgery (for example, cesarean sections or hip replacements) become very high risk. Which is not only scary on medical treatment level but also significantly increases healthcare costs, with prolonging hospital stay and more intensive care required. This is exactly where solutions like the one of Trobix Bio comes into play.

"The Covid-19 pandemic stresses the urgent need to tackle the global challenges of infectious diseases, and the global need for a solution to the threat of antimicrobial resistance was there from day one", says Eyal Agmoni, Chairman of Chartered Group. "Trobix Bio is set to revolutionize the landscape of phage-based nanomedicine by introducing its game-changing, precision particle disruptive technology. We are very happy with the progress made by the team and are glad to be part of this unique venture".

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What happens when bacteria resist treatment? Trobix lands $3M to protect us from next 'Super Bug' - Geektime

Global Healthcare Nanotechnology (Nanomedicine) Market Worth $475B by 2027 – Therapeutics Will Account for $369B – Benzinga

Dublin, Aug. 05, 2020 (GLOBE NEWSWIRE) -- The "Healthcare Nanotechnology (Nanomedicine) - Global Market Trajectory & Analytics" report has been added to ResearchAndMarkets.com's offering.

The publisher brings years of research experience to this 9th edition of the report. The 190-page report presents concise insights into how the pandemic has impacted production and the buy side for 2020 and 2021. A short-term phased recovery by key geography is also addressed.

Global Healthcare Nanotechnology (Nanomedicine) Market to Reach $475.2 Billion by 2027

Amid the COVID-19 crisis, the global market for Healthcare Nanotechnology (Nanomedicine) estimated at US$183.9 Billion in the year 2020, is projected to reach a revised size of US$475.2 Billion by 2027, growing at a CAGR of 14.5% over the analysis period 2020-2027.

Therapeutics, one of the segments analyzed in the report, is projected to record a 14.1% CAGR and reach US$369.5 Billion by the end of the analysis period. After an early analysis of the business implications of the pandemic and its induced economic crisis, growth in the Regenerative medicine segment is readjusted to a revised 15.7% CAGR for the next 7-year period.

The U.S. Market is Estimated at $54.3 Billion, While China is Forecast to Grow at 14% CAGR

The Healthcare Nanotechnology (Nanomedicine) market in the U.S. is estimated at US$54.3 Billion in the year 2020. China, the world's second largest economy, is forecast to reach a projected market size of US$82.8 Billion by the year 2027 trailing a CAGR of 14% over the analysis period 2020 to 2027.

Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at 12.8% and 12.5% respectively over the 2020-2027 period. Within Europe, Germany is forecast to grow at approximately 10.7% CAGR.

In-vitro diagnostics Segment to Record 16.3% CAGR

In the global In-vitro diagnostics segment, USA, Canada, Japan, China and Europe will drive the 16.1% CAGR estimated for this segment. These regional markets accounting for a combined market size of US$5.7 Billion in the year 2020 will reach a projected size of US$16.2 Billion by the close of the analysis period.

China will remain among the fastest growing in this cluster of regional markets. Led by countries such as Australia, India, and South Korea, the market in Asia-Pacific is forecast to reach US$56.9 Billion by the year 2027.

Competitors identified in this market include, among others:

Total Companies Profiled: 46

For more information about this report visit https://www.researchandmarkets.com/r/moa2yk

Research and Markets also offers Custom Research services providing focused, comprehensive and tailored research.

Read the rest here:
Global Healthcare Nanotechnology (Nanomedicine) Market Worth $475B by 2027 - Therapeutics Will Account for $369B - Benzinga

In COVID-19 Crisis, Older Canadians Are More Resilient than Younger Generations, Research Finds – The Suburban Newspaper

Edward Jones, in partnership with Age Wave, released a landmark study on Aug. 4 that takes a comprehensive look at retirement in Canada, focusing specifically on four central pillars: health, family, purpose and finances.

The study examines trends affecting the rapid transformation of retirement in Canada as the country's aging population approaches this new stage of life. This includes the impact of COVID-19 which has accelerated many of the trends unearthed in this study.

Despite COVID-19's severe and disproportionate impact on the health of aging adults, older Canadians reported they are coping far better than younger ones. "The Four Pillars of the New Retirement" study of 1,000 Canadian respondents across five-generations revealed that 38 per cent of Gen Z and 36 per cent of millennials said they have suffered mental health declines since the pandemic began, while only 20 per cent of baby boomers and 7 per cent of silent generation respondents said the same. The majority of Canadian retirees (51 per cent) defined retirement as a whole new chapter filled with new choices, freedoms and challenges, and they do so in a more holistic way across four important areas of health, family, purpose and finance.

"We've certainly seen COVID-19's disruptive influence on finances, with the pandemic impacting retirement timing and financial confidence," said David Gunn, Country Leader, Edward Jones Canada. "However, the pandemic has brought families closer and renewed the focus on important discussions about planning earlier for retirement, saving more for emergencies and even talking through end-of-life plans and long-term care costs."

"COVID-19's impact forever changed the reality of many Canadians, yet we've observed a resilience among Canadian retirees in contrast to younger generations," said Ken Dychtwald, Ph.D., psychologist/gerontologist and founder and CEO of Age Wave. "Older Canadians recognize the value of a long-term view, and so as they think about their lives, longevity and legacy, they're able to pull from an array of experiences that help them weather current storms, feel gratitude about many aspects of their lives and still plan for the future."

The four pillars to living well in the "new retirement"

The study goes beyond the impacts of COVID-19 and outlines what makes today's retirement "new". Canada's retirement landscape is unique - increasing longevity and a groundswell of Boomers entering retirement make this one of the most significant societal shifts in history. The study found, changing attitudes and aspirations coupled with external forces (i.e. economic downturns, the pandemic, technology, etc.) have drastically changed the expectations of those approaching or entering retirement and will shape what retirement looks like for generations to come.

The study identified four key pillars for living well in the "new retirement":

When it comes to living well in retirement, 97 per cent of retirees and 99 per cent of those age 75 and over, say that health is more important than wealth. 91 per cent of Canadian retirees say it's never too late to improve health, however, there is an intention/action gap as 51 per cent of Canadian retirees don't exercise regularly, and 33 per cent say they don't maintain a healthy diet. While physical health usually declines with age, for many Canadians mental health rises.

A bright spot coming out of the pandemic is the deepening of family ties. Two-thirds of Gen Z define family as "anyone they love and care for, regardless of whether they are related by blood, marriage or adoption." They believe in "families of affinity" or families of choice. As we approach what is expected to be the largest generational wealth transfer in recent memory, retirees cite they worry about their children more (44 per cent) and are willing to do whatever it takes, personally and financially, to support family members in need, even if it means sacrificing their own financial security (63 per cent). The study also found, 47 per cent of Canadians overall and 30 per cent of Canadians age 65 and over have yet to begin discussing their end-of-life care preferences with their family or close friends.

Retirees with a strong sense of purpose are happier, healthier and live longer, according to the study. This cohort reports they find their strongest sense of purpose from spending time with loved ones (72 per cent) and many (46 per cent) find purpose by being generous or helping others, particularly women (54 per cent). They are also looking for meaningful ways to carve out their free time. They don't just want to keep busy; they want to make useful and rewarding contributions to community and family. As the country's population continues to age, 89 per cent of Canadians agree that there should be more ways for retirees to help in their communities.

According to the study, a chief financial goal amongst retirees, is to have enough resources to provide security (48 per cent) and the freedom to live the lives they want (47 per cent). Retirees' greatest financial worry is not economic uncertainty like recessions, inflation or taxes, despite the disruption associated with COVID-19. Their greatest concerns are encountering unexpected expenses (54 per cent) and the cost of health care, including long-term care (47 per cent). Pre-retirees express even higher concerns about health and long-term care (59 per cent) with three quarters of those who plan to retire (74 per cent) stating they have no idea what their health and long-term care costs may be in retirement.

"Beyond finances, we can help our clients envision and truly realize a holistic and fulfilling retirement, which, we know includes decisions about their health, family and purpose," said Gunn. "Empathy and knowledge allow us to better serve as a trusted advisor to our clients in a human-centered way and work together to achieve what's most important to Canadians and their families."

While the above findings feature a selection of data regarding the new definition of retirement, further examination of the four pillars of health, family, purpose and finances reveal their highly intertwined nature and influence in shaping retirees' overall quality of life. For the complete study, please visit http://www.edwardjones.ca/newretirement

Edward Jones is a full-service investment dealer with more than 850 financial advisors in Canadian communities from coast-to-coast.

Edward Jones Canada, http://www.edwardjones.ca

Age Wave, http://www.agewave.com

AB

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In COVID-19 Crisis, Older Canadians Are More Resilient than Younger Generations, Research Finds - The Suburban Newspaper

In COVID-19 Crisis, Older Americans Are More Resilient Than Younger Generations, Edward Jones and Age Wave Research Finds – PRNewswire

ST. LOUIS, Aug. 4, 2020 /PRNewswire/ --Despite COVID-19's severe and disproportionate impact on the health of aging adults, older Americans reported they are coping far better than younger ones, according to the Edward Jones and Age Wave study released today, "The Four Pillars of the New Retirement." The9,000-person, five-generation study in the U.S. and Canada revealed that in the U.S. 37% of Gen Z and 27% of millennials said they have suffered mental health declines since the pandemic began, while only 15% of baby boomers and 8% of silent generation respondents said the same.

"COVID-19's impact forever changed the reality of many Americans, yet we've observed a resilience among U.S. retirees in contrast to younger generations," said Ken Dychtwald, Ph.D., psychologist/gerontologist and founder and CEO of Age Wave. "Older Americans tend to recognize the value of a long-term view, and so as they think about their lives, longevity and legacy, they're able to pull from an array of experiences that help them weather current storms, feel gratitude about many aspects of their lives and still plan for the future."

The landmark Edward Jones and Age Wave research uncovered a new definition for retirement, as far more than simply the end of work. The majority of U.S. retirees (55%) defined retirement as a whole new chapter filled with new choices, freedoms and challenges, and they do so in a more holistic way across four important areas of health, family, purpose and finance.

COVID-19's Impact on Family Closeness and Finances COVID-19's initial dramatic impact on the U.S. economy and personal financial situations may very well leave long-lasting implications. Reflecting a great deal of generational generosity, 24 million Americans* have provided financial support to adult children due to COVID-19, and an overwhelming 71% of retirees said they would offer financial support to their family even if it could jeopardize their own financial future. Despite COVID-19's negative impact on finances, 67% of Americans said the pandemic has brought their families closer together. The research also revealed that 20 million Americans stopped making retirement savings contributions during the COVID-19 pandemic and only a quarter of working Americans were on track with their retirement savings prior to the pandemic.[i]

"We've certainly seen COVID-19's disruptive force on finances, with the pandemic influencing retirement timing and financial confidence," said Ken Cella, Edward Jones Client Services Group Principal. "However, this cloud has brought several silver linings in terms of family closeness and important discussions about planning earlier for retirement, saving more for emergencies and even talking through end-of-life plans and long-term care costs."

Social Relationships as Predictor of Health and Purpose While loneliness is pervasive across all five generations, as people age, physical isolation becomes a greater health risk, as deadly as smoking a pack of cigarettes a day[ii], and it is linked to increased risk for heart disease and dementia.[iii]While most retirees (76%) said they derive the greatest sense of purpose from social relationships, specifically time spent with loved ones, 72% noted that one of their biggest fears is becoming a burden on their families.

"Retirees say they miss people and purpose, not paychecks, when they retire, but 31% of new retirees are struggling to find purpose in this stage of life. They want to feel useful, not just youthful, and keep learning and growing at every age," Dychtwald added.

The study found that 89% of all Americans feel that there should be more ways for retirees to use their talents and knowledge for the benefit of their communities and society at large.

Financial Advisors as Connectors and Confidence Builders As Americans redefine retirement in a broader way across the four pillars, the majority of U.S. respondents felt their ideal financial advisor is a guide who can understand them and help them achieve their goals. In fact, 84% of those working with a financial advisor said that their financial advisor relationship gave them a greater sense of comfort regarding their finances during the pandemic.

Further underscoring the fundamental importance of financial security, retirees are often met by new challenges as they enter retirement. Thirty-six percent of retirees said managing money in retirement is more confusing than saving for retirement, and they want help navigating. Fifty-two percent of retirees cited healthcare costs, including long-term care, as the most common financial worry. This concern was also echoed by pre-retirees as more than two-thirds (68%) of those who plan to retire in the next 10 years said they have no idea what their healthcare and long-term care costs will be in retirement.

"Beyond finances, we can help our clients envision and truly realize a holistic retirement, which, we know includes decisions about their health, family and purpose," said Cella. "Empathy and knowledge allow us to better serve our clients in a human-centered way and work together to achieve what's most important to them and their families."

While the above findings feature a selection of respondents' thoughts regarding the new definition of retirement, further examination of the four pillars of health, family, purpose and finances reveal their highly intertwined nature and influence in shaping retirees' overall quality of life. For more details from The Four Pillars of the New Retirement, please visit http://www.EdwardJones.com/NewRetirement.

MethodologyThis report is based on a large-scale investigation of what it means to live well in retirement that began in November 2019. The study was conducted by Edward Jones in partnership with Age Wave and The Harris Poll.

As part of the study, The Harris Poll conducted an online, representative survey from May 21 through June 4, 2020among more than 9,000 adults age 18+, in the US and Canada, including n=3,000 among a US general population, n=1,000 among a Canadian general population, and oversamples of approximately 500 in each of the following 10 metropolitan regions: Atlanta, Charlotte, Cleveland, Dallas, Kansas City, Los Angeles, Portland, Raleigh-Durham, St. Louis, and Toronto.Results were weighted where necessary to bring them into line with their actual proportions in the population.

*Estimated projections to the US population are calculated based on the 2019 Census Current Population Survey.

About Edward Jones Edward D. Jones & Co., L.P., a Fortune 500 company headquartered in St. Louis, provides financial services in the U.S. and, through its affiliate, in Canada. Every aspect of the firm's business, from the investments offered to the location of branch offices, caters to individual investors. The firm's 19,000-plus financial advisors serve more than 7 million clients with a total of $1.2 trillion in client assets under care. Visit http://www.edwardjones.comor the recruiting website at http://www.careers.edwardjones.com. Member SIPC.

About Age Wave Under the leadership of Founder and CEO Ken Dychtwald, Ph.D., Age Wave is the nation's foremost thought leader on population aging and its profound business, social, financial, health care, workforce, and cultural implications. Dychtwald's long-awaited new book What Retirees Want: A Holistic View of Life's Third Age was just published (Wiley, July 15,2020). Since its inception in 1986, the firm has advised numerous non-profits and over half the Fortune 500. For more information, please visitwww.agewave.com.

About The Harris Poll The Harris Poll is one of the longest-running surveys in the U.S.;tracking public opinion, motivations and social sentiment since 1963. The Harris Poll is now part of Harris Insights & Analytics, a global consulting and market research firm that delivers social intelligence for transformational times. The Harris Poll works with clients in three primary areas; building twenty-first-century corporate reputation, crafting brand strategy and performance tracking, and earning organic media through public relations research. Learn more atwww.theharrispoll.com

[i]Federal Reserve, Report on the Economic Well-Being of U.S. Households in 2018 - May 2019

[ii]Holt-Lunstad J, Smith TB, Layton JB. Social relationships and mortality risk: a meta-analytic review. PLoS Med., July 2010

[iii]National Institute on Aging, "Social isolation, loneliness in older people pose health risks," April 23, 2019.

SOURCE Edward Jones

https://www.edwardjones.com

Link:
In COVID-19 Crisis, Older Americans Are More Resilient Than Younger Generations, Edward Jones and Age Wave Research Finds - PRNewswire

Global Healthcare Nanotechnology (Nanomedicine) Market Worth $475B by 2027 – Therapeutics Will Account for $369B – GlobeNewswire

Dublin, Aug. 05, 2020 (GLOBE NEWSWIRE) -- The "Healthcare Nanotechnology (Nanomedicine) - Global Market Trajectory & Analytics" report has been added to ResearchAndMarkets.com's offering.

The publisher brings years of research experience to this 9th edition of the report. The 190-page report presents concise insights into how the pandemic has impacted production and the buy side for 2020 and 2021. A short-term phased recovery by key geography is also addressed.

Global Healthcare Nanotechnology (Nanomedicine) Market to Reach $475.2 Billion by 2027

Amid the COVID-19 crisis, the global market for Healthcare Nanotechnology (Nanomedicine) estimated at US$183.9 Billion in the year 2020, is projected to reach a revised size of US$475.2 Billion by 2027, growing at a CAGR of 14.5% over the analysis period 2020-2027.

Therapeutics, one of the segments analyzed in the report, is projected to record a 14.1% CAGR and reach US$369.5 Billion by the end of the analysis period. After an early analysis of the business implications of the pandemic and its induced economic crisis, growth in the Regenerative medicine segment is readjusted to a revised 15.7% CAGR for the next 7-year period.

The U.S. Market is Estimated at $54.3 Billion, While China is Forecast to Grow at 14% CAGR

The Healthcare Nanotechnology (Nanomedicine) market in the U.S. is estimated at US$54.3 Billion in the year 2020. China, the world's second largest economy, is forecast to reach a projected market size of US$82.8 Billion by the year 2027 trailing a CAGR of 14% over the analysis period 2020 to 2027.

Among the other noteworthy geographic markets are Japan and Canada, each forecast to grow at 12.8% and 12.5% respectively over the 2020-2027 period. Within Europe, Germany is forecast to grow at approximately 10.7% CAGR.

In-vitro diagnostics Segment to Record 16.3% CAGR

In the global In-vitro diagnostics segment, USA, Canada, Japan, China and Europe will drive the 16.1% CAGR estimated for this segment. These regional markets accounting for a combined market size of US$5.7 Billion in the year 2020 will reach a projected size of US$16.2 Billion by the close of the analysis period.

China will remain among the fastest growing in this cluster of regional markets. Led by countries such as Australia, India, and South Korea, the market in Asia-Pacific is forecast to reach US$56.9 Billion by the year 2027.

Competitors identified in this market include, among others:

Total Companies Profiled: 46

For more information about this report visit https://www.researchandmarkets.com/r/moa2yk

Research and Markets also offers Custom Research services providing focused, comprehensive and tailored research.

The rest is here:
Global Healthcare Nanotechnology (Nanomedicine) Market Worth $475B by 2027 - Therapeutics Will Account for $369B - GlobeNewswire

Scientists Found a Way to Tweak Proteins That Prolongs Life of Roundworms, Will It Work on Humans Too? – Science Times

Scientists from the Korea Advanced Institute of Science and Technology (KAIST) have found a way to tweak proteins that control cellular activity levels. That means they were able to turn up and down levels in roundworm that prolongs its lifespan.

In that sense, drugs could be designed to combat age-related problems and increase the lifespan of humans.

The enzyme in roundworms that the scientists tweaked is responsible for converting the sugar into energy when the cellular level is low, in which they found that it can be controlled. Like roundworms, humans also have these proteins, which means that there is a possibility of developing longevity-promoting drugs.

(Photo: Pixabay)Scientists Found A Way To Tweak Proteins That Prolongs Life of Roundworms, Will It Work on Humans Too?

Read: Long Life: Here's How to Extend Your Lifespan According to Science

One of the most commonly used in lab testing, the Korean scientists used the roundworm Caenorhabditis elegans(C. elegans) for their study, published in Science Advances.

C. elegans experienced a boost in its lifespan when the scientists altered a couple of proteins responsible for monitoring the cellular energy levels.

These proteins are the VRK-1 and AMPK, and both work in tandem in roundworm cells. VRK-1's job is to tell AMPK to stick a phosphate molecule on it. AMPK's role then is to monitor the energy levels in cells when it is running low.

In short, VRK-1controls AMPK, and AMPK controls the cellular energy levels. The researchers were able to turn up and down the cellular activity that tells it to produce VRK-1 protein through various biological research tools, such as introducing foreign genes into the roundworm.

Pretty much, this gene remained unchanged over the course of evolution, which is why most complex organisms, including humans, have it.

According to lead author Sang-soon Park, he and his colleagues successfully increased the production of VRK-1 protein that boosts the lifespan of roundworms. They found that its activity increased when the worm has low cellular energy levels.

Simply saying, there is reduced mitochondrial respiration, and a decline in its function are associated with age-related illness. Mitochondriais the powerhouse of a cell.

However, the mild inhibition of mitochondrial respiration has shown to promote a longer lifespan for other species like flies and mammals.

Read Also:Scientists to Improve "Longevity Gene" Efficiency in Battling the Aging Process

When Park and his colleagues tried tweaking the same protein in humans, they found that they could also replicate the same process that occurs in roundworms.

Moreover, Professor Seung-Jae V. Lee, one of the researchers, explained that their research raises a very intriguing possibility that VRK-1 can also increase human lifespan. Perhaps drugs that promote longevity can be developed to alter the activity of VRK-1.

In that way, humans will be able to combat age-related illnesses that involve the disruption of chemical reactions in the body and diseases of the mitochondria.

But the researchers advise conducting more research to better understanding the workings of VRK-1 before developing longevity drugs. They added that they still need to figure out the exact mechanics of how AMPK controls energy levels in cells.

Read More: Are Scientists Close to Discovering a Way to Delay Aging?

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Scientists Found a Way to Tweak Proteins That Prolongs Life of Roundworms, Will It Work on Humans Too? - Science Times

Nine Cambridge researchers among this year’s Royal Society medal and award winners – Cambridge Network

President of the Royal Society, Venki Ramakrishnan, said: "The Royal Societys medals and awards celebrate those researchers whose ground-breaking work has helped answer fundamental questions and advance our understanding of the world around us. They also champion those who have reinforced sciences place in society, whether through inspiring public engagement, improving our education system, or by making STEM careers more inclusive and rewarding.

"This year has highlighted how integral science is in our daily lives, and tackling the challenges we face, and it gives me great pleasure to congratulate all our winners and thank them for their work."

Sir Alan Fersht FMedSci FRS, Emeritus Professor in the Department of Chemistry and former Master of Gonville and Caius College, is awarded the Copley Medal for the development and application of methods to describe protein folding pathways at atomic resolution, revolutionising our understanding of these processes.

"Most of us who become scientists do so because science is one of the most rewarding and satisfying of careers and we actually get paid for doing what we enjoy and for our benefitting humankind. Recognition of ones work, especially at home, is icing on the cake," said Sir Alan. "Like many Copley medallists, I hail from a humble immigrant background and the first of my family to go to university. If people like me are seen to be honoured for science, then I hope it will encourage young people in similar situations to take up science."

As the latest recipient of the Royal Societys premier award, Sir Alan joins an elite group of scientists, that includes Charles Darwin, Albert Einstein and Dorothy Hodgkin, and more recently Professor John Goodenough (2020) for his research on the rechargeable lithium battery, Peter Higgs (2015), the physicist who hypothesised the existence of the Higgs Boson, and DNA fingerprinting pioneer Alec Jeffreys (2014).

Read the full story, with the complete list of Cambridges 2020 winners and their award citations

Reproduced courtesy of the University of Cambridge

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Nine Cambridge researchers among this year's Royal Society medal and award winners - Cambridge Network

What are ACE scores and why do they matter? – Record Searchlight

Shasta County health officials revealed a 5-year public health plan that focuses on prevention and fighting Adverse Childhood Experiences.

When Kaiser Permanente and the U.S. Centers for Disease Control and Prevention launched the study to measure Adverse Childhood Experiences (ACE) levels in Shasta County in 2012, the results they found were striking.

The ACE study examined categories of childhood physical and emotional abuse and neglect. It measured household dysfunction includingdomestic violence, mental illnessand substance abusethat create toxic stress leading to neuro-system changes during child development.

The higher the ACE score a child has, the higher the risk of developing chronic illnesses like heart disease, chronic obstructive pulmonary disease (COPD), depression and cancer.

More: Hotline launches to support Shasta County parents and caregivers through COVID-19

Shasta Countys ACE score was found to be double the state average. Forty percent of the adults surveyed in Shasta County reported a score of 4 or higher.

Since the study published, schools, youth centersand even law enforcement officials have adopted trauma-sensitive methods to support youth trying to develop healthy coping mechanisms to overcome trauma.

Almost all Shasta County school districts have attended a trauma-informed training or received ACEs training with the Shasta County Office of Education.

The Happy Valley Primary School was able to overwhelmingly decrease bad behavior offenses in the last three years, Principal Shelly Craig said. The Shasta County Probation Department began tracking juvenile behavior patterns in order to reverse them as well, Chief Probation Officer Tracie Nealsaid viaemail.

Peer Court jury training by the Anderson Police in 2019.(Photo: Youth Options Shasta)

Susan Wilson, executive director of Youth Options Shasta and steering committee member of the Strengthening Families Collaborative, said the study was the confirmation of a problem that youth groups and health agency administrators knew had beenprevalent for a long time.

We have struggled in the northern part of California. We have struggled for a long time. We have struggled because we have low education levels. We have struggled because we have high poverty. We have high poor results in physical health. Statistics show that our kids are not learning at the same level as the kids typical in California, Wilson said.

Before the study published, Wilson and other community organizers were already putting together the Strengthening Families Collaborative curriculum, and introducing Protective Factors for Mental, Emotional, and Behavioral Disorders variables that promote developmental competencies in youth.

All these things happened together, not as a result of the ACEs study. The ACEs study was almost a confirmation of the problem that we knew we had. In other words, we knew kids were not doing well, Wilson said. But we didnt have the background of ACEs, the study, the data, to inform us. When we did the study and got the results we sat back like wow.

After the ACEs study, organizations like Youth Options Shasta, which connects youth to peer court and restorative justice practices, began to incorporate some additional screening when evaluating teenagers, an at-risk population with high ACE scores that the group works with.

Peer court youth jury deliberations in the jury room.(Photo: Youth Options Shasta)

ACEs are predictable and as a result, preventable, said Kelly Rizzi, director of School and District Support at Shasta County Office of Education. Rizzi joined the Shasta County Office of Education seven years ago to address the literacy issue in Shasta County, but learned the bleak literacy levels were related to trauma.

Many of the students who were struggling with literacy were living in toxic stress conditions and persistent fear, Rizzi said, damaging their amygdala the part of the brain that plays an importantrolesin the expression of emotion and behavior. That unrelenting stress can also shutoff the learning and growth that takes place in the prefrontal cortex of the brain, which is linked to decision making andreasoning.

What we really have is a regulation gap, not an education gap, Rizzi said. What we learned is we can teach kids to self-regulate. Your ACE score doesnt define you; it informs you and empowers you to make different decisions for yourself, your family and community.

More: Coronavirus live updates: Twelve more Shasta County residents test positive

In the last ten years a whole generation has come into adulthood but the population is changing slowly. To measure the effectiveness of the community's response to address high ACE scores in real time, it starts with the children, said Donnell Ewert, Director of the Shasta County Health and Human Services Agency.

Some experts question whether its wise to ask children about traumatic life events to generate a trend, out of concern that itll have an adverse effect on young people. Organizations and schools have begun efforts to respond to ACEs, but the challenge is measuring the effectiveness of the initiatives, Ewert said.

He said that the agency has frameworks in place to measure behavior shifts in people involved with the probation department, as well as the homeless populationand other high-risk populations.

But, Ewert said, the high ACE scores will not change dramatically in a short period of time.It will take years to see a difference.

Almost all Shasta County school districts have adopted a "social-emotional learning" program in the last fiveyears and noticed a reduction in bad behavior, Rizzi said. That is one way of tracking the effectiveness of ACEs reduction efforts.

Peer Court trial held in Shasta Lake City Council Chambers in 2016.(Photo: Youth Options Shasta)

The reality is, if youre not talking about it on a regular basis, it goes by the wayside, Rizzi said. Before COVID-19, schools began holding ACEs training for parents but now we cant hold gatherings. Our best bet is to teach the teachers and kids in classes.

At Happy Valley Primary School, Craig, the principal, began assessing the response to students basic needs by measuring daily and weekly data ranking bad behavior at a low level, medium level or high level.

Happy Valley has a total of about 490 students, with 240 primary students inpre-K through third grade. The trauma-informed practices, behavior dataand systems Craig adopted when she began working at the district three years ago have benefited the student body and decreased incidents of bad behavior significantly, she said.Students are taught to self-regulate by relating to issues and identifying coping methods so they can return to learning.

More: What will the new school year look like in Shasta County school districts?

The longevity data is going to be crucial moving forward, but in the first year as principal, I was spending 80% of my time focused on student discipline, and as Im transitioning out of this year (third year), I would say 7% of my time is spent on student discipline, Craig said. Its a significant culture change. It just looks different.

Reversing the risky effects of high ACE scores in the community is difficult but not impossible, Wilson said.

Youth advisory members attend the annual California Youth Court Summit trip in 2014.(Photo: Youth Options Shasta)

Another method of measuring the effectiveness of the community response can be tracking the number of toxicology screenings at birth whichcould indicate that mothers are paying attention to risks caused by ACEs, such as substance abuse.

People who successfully complete probation demonstrate an ability to overcome the high level of ACE scores and transform negative behavior patterns, she added.

At the Shasta County Probation Department, Neal collects data to include short, moderateand long term goals and analyzes the data every sixmonths. Staff is trained to develop cognitive skills and work with traumatized youth, she said.

Some key observation points include school graduation rates, employment, truancy, parental involvement and the level of conflict within the home. Success with mental health and substance abuse treatments are also considered.

"There is an emphasis on gender-specific trauma groups and exploring what trauma impacts people, developing awareness to triggers and healthy coping skills," Neal said in an email. "Being involved in the juvenile criminal justice system creates an enormous amount of stress and trauma in itself."

Nada Atieh is a Report For America corps member and education reporter focusing on childhood trauma and the achievement gap for the Redding Record Searchlight. Follow her on Twitter at @nada_atieh. Help local journalism thrive by subscribing today!

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What are ACE scores and why do they matter? - Record Searchlight

Testosterone Replacement Therapy Market 2020 Segments Analysis: Companies Bayer HealthCare Pharmaceuticals, Sandoz, Clarus Therapeutics, TesoRx -…

The Global Testosterone Replacement Therapy Market Report enfolds a comprehensive analysis and assessment of the global Testosterone Replacement Therapy market. The report mainly intends to help market players and clients to understand the market in terms of structure, scope, profitability, attractiveness, and growth possibilities. The report also highlights a detailed review of market segmentation, potentials, emerging trends, and volatilities in the global Testosterone Replacement Therapy market.

Also, precise evaluation of market revenue, sales volume, global demand, and production is covered in the global Testosterone Replacement Therapy market report. The report further illuminates a thorough assessment of market competition, major market players, and the global Testosterone Replacement Therapy industry environment. It also underscores crucial market dynamics, pricing trends, demand-supply proportions, growth-driving forces, market restraining factors, and limitations in the global Testosterone Replacement Therapy market these poses a direct impact on the development of the market.

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The market ruining disaster of COVID-19 has been severely affecting all fields of the global economy as well as the global Testosterone Replacement Therapy market. The pandemic has disrupted well-ordered market operations across the world. Though, the global Testosterone Replacement Therapy market is expected to reach projected CAGR during the forecast period as rising technological development, product innovations, and rapid industrializations are likely to boost market development in the near future. Also, soaring Testosterone Replacement Therapy demand, raw material affluence, adept infrastructures, and product awareness are uplifting the Testosterone Replacement Therapy market growth.

The leading companies are operating in the Testosterone Replacement Therapy industry at global and regional levels to cater to the rising demand for the Testosterone Replacement Therapy . The companies also execute various product research, innovation, development, and technology adoptions to offer better fit products in the market. The report examines all their efforts alongside business strategies, which include product launches, brand promotions, mergers, acquisitions, amalgamations, and ventures.

Companies production bases, capacities, manufacturing volume, product specifications, raw material, concentration rate, cost analysis, major vendors, global presence, distribution networks, serving segments, and effective production processes are evaluated in the report that offers the detailed notion of each companys organizational structure.

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Significantly, the report reviews their financial status by assessing gross margin, profit, sales volume, production cost, pricing structure, revenue, and growth rate. The referred analysis prompted other market contenders and investors to comprehend the strengths, weaknesses, and market positions of their rivals.

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Testosterone Replacement Therapy Market 2020 Segments Analysis: Companies Bayer HealthCare Pharmaceuticals, Sandoz, Clarus Therapeutics, TesoRx -...

Here’s What Stress Is Doing to Your Health and Testosterone – The Good Men Project

Stress is ubiquitous it affects all of us one way or another. Low-level stress that you can easily overcome is usually not bad for you. In fact, it can even be good for you. Stress can motivate you, improve your athletic performance, and help you adapt to your environment.

But long-term or excessive stress can have a profoundly negative effect on your health and even reduce your lifespan. Research shows that stress reduces testosterone levels, which may be one reason why stress is strongly linked with weight gain, poor sleep, and erectile dysfunction (ED).

Getting your stress under control is one of the most important ways to achieve a healthy, satisfying life. In this article, Ill dive into exactly what stress is and what it is doing to your health, testosterone, and sex life. Then Ill explain exactly how to beat it.

We throw the term around all the time, but what exactly is stress?

Stress is a feeling of psychological strain or pressure. It occurs from our own perception of an event or stressor as threatening or challenging to us. To be clear, stress is not the actual events or stressors in your life. Your response to those stressors is what triggers your feeling of stress.

Psychologists sometimes classify stressors into four types (1):

1. Ambient stressors, like noise in a cafe or traffic.2. Hassles or micro stressors, like not being able to find your keys.3. Major life events, like getting fired, getting married, or having a child.4. Crises or catastrophes, like a natural disaster.

These have different effects on your overall well-being, but even hassles or micro stressors, when they are constant, can create levels of stress that ultimately affect our health.

Stress has a massive physiological effect on our bodies. When we feel stress, our brain sends out a signal to our body and activates a fight or flight response. Our pupils dilate, our heart rate increases and our body releases a number of hormones and chemicals to get us ready to react such as adrenaline, endorphins, and cortisol.

This response is useful if were encountering a situation where we really do need to fight or get away. Athletes, soldiers in combat, or even firefighters benefit from this reaction to stressful situations.

But for most of us, this bodily response is unnecessary. And, when stress is chronic, occurring over a long period of time, these effects can be toxic and dangerous to our health. The amount of stress that you have, and your stress resiliency, can even predict how long you will live.

Risk of Disease

One of the most worrying effects of stress on our health is its relationship to disease; research shows that chronic, severe stress vastly increases a persons risk for several chronic health conditions.

For example, theres significant evidence that stress increases the risk of cardiovascular diseases like heart attack, stroke, high blood pressure, and hypertension as well as diabetes and certain types of cancer (2, 3, 4). Stress is also clearly associated with mental illness, including depression, schizophrenia, and anxiety (5, 6).

Immune Function

Studies have shown that stress clearly reduces immune function and can cause a person to be more susceptible to illnesses like colds. Scientists have suggested that stress can affect immune system function at the cellular level, changing the bodys chemical immune response.

Poor Lifestyle Habits

The way that we cope with stress may also have an impact on our health. When individuals cope with stress by consuming excessive alcohol, smoking, or binge-eating, the result is poorer health. Stress can cause some people to engage in unhealthy habits as a way to cope with the psychological discomfort.

Stress has such a powerful effect on us in part because its psychological. It affects the hormonal balance in our body, but it also affects our mental health. Both aspects can impact sexual function and performance.

Stress has been shown to directly affect testosterone levels. When youre stressed, your body releases the stress hormone cortisol. And high cortisol levels crush your testosterone.

Research has found a clear association between high cortisol levels and low levels of testosterone. The lowered testosterone levels caused by stress, in turn, leads to low energy, weight gain, loss of mental focus, and loss of sexual function.

And stress is one of the most common causes of ED. Sexual function depends on the complex interaction between physiological and psychological factors. Besides reducing testosterone levels, which contribute to erectile dysfunction, it can also affect the psychological processes associated with sexual arousal.

Finding ways to effectively cope with stress is an essential part of creating a healthy lifestyle, achieving optimal testosterone levels, and supporting a fulfilling sex life. But how?

Develop Stress Resiliency

This is one of the most important things that you can do to reduce stress: develop ways to cope effectively with stress and create stress resiliency.

Stress resiliency refers to your ability to respond to and cope with the stressors that you face in everyday life. Creating resilience to stress can help you experience it less often, for less time, and thus reduce the negative health effects.

To develop stress resiliency, try the following:

1. Start to think of stress as an opportunity for growth. Ask yourself: What is the stressor? Why am I stressed about it? Where can I feel the stress in my body? What can I do right now to cope and calm myself down? What can I learn to grow from it?

2. Develop healthy coping habits. These include exercise, meditation, breathing techniques, hobbies you enjoy, and even sex.

3. Sleep! Sleep is critical for optimal health, but especially when it comes to stress resilience. Good quality sleep allows your body to heal and recover. And good quality sleep lowers cortisol.

4. Get social support. Engaging with the important people in your life is one of the most effective ways to cope with stress. Even giving social support can improve your stress.

5. Focus on eating good quality food. The foods you eat can directly promote or reduce inflammation in your body, and thus affect cortisol production.

Exercise

Exercise is one of the most effective ways to beat back stressors (15). Research shows that people who exercise consistently are better able to develop stress resilience and reduce the health consequence of stress (16).

Meditation

Research is increasingly finding the benefits of meditation on everything from cognitive health to physical energy levels. Meditation also turns out to be an effective way to cope with life stressors, even if you do it for just five to ten minutes a day.

The benefits of meditation include:

Stress reduction Better sleep Feeling relaxed Better focus and attention More positive mood Reductions in depression and anxiety.

Everyone experiences stress. If stress becomes chronic, and you lose your ability to cope with it, stress can crush your health, leading to weight gain, low testosterone levels, poor energy, and increased risk of erectile dysfunction.

But, when you have effective coping mechanisms and view stress as helpful not harmful, you can overcome it and rise to the occasion. Learning to beat stress will help you boost your immune system, lose weight, feel healthier, and enjoy the benefits of higher testosterone.

1. Wheaton, B., & Montazer, S. (2010). Stressors, stress, and distress. A handbook for the study of mental health: Social contexts, theories, and systems, 171-199.

2. Dimsdale, J. E. (2008). Psychological stress and cardiovascular disease. Journal of the American College of Cardiology, 51(13), 1237-1246.

3. Harris, M. L., Oldmeadow, C., Hure, A., Luu, J., Loxton, D., & Attia, J. (2017). Stress increases the risk of type 2 diabetes onset in women: A 12-year longitudinal study using causal modelling. PloS one, 12(2), e0172126.

4. Mo
reno-Smith, M., Lutgendorf, S. K., & Sood, A. K. (2010). Impact of stress on cancer metastasis. Future Oncology, 6(12), 1863-1881.

5. Bartolomucci, A., & Leopardi, R. (2009). Stress and depression: preclinical research and clinical implications. PloS one, 4(1), e4265.

6. Corcoran, C., Mujica-Parodi, L., Yale, S., Leitman, D., & Malaspina, D. (2002). Could stress cause psychosis in individuals vulnerable to schizophrenia?. CNS Spectrums, 7(1), 33.

7. Segerstrom, S. C., & Miller, G. E. (2004). Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry. Psychological Bulletin, 130(4), 601.

8. Cohen, S., Doyle, W. J., Skoner, D. P., Rabin, B. S., & Gwaltney, J. M. (1997). Social ties and susceptibility to the common cold. JAMA, 277(24), 1940-1944.

9. Steptoe, A., Wardle, J., Pollard, T. M., Canaan, L., & Davies, G. J. (1996). Stress, social support and health-related behavior: a study of smoking, alcohol consumption and physical exercise. Journal of Psychosomatic Research, 41(2), 171-180.

10. Mulligan, C. J. (2016). Early environments, stress, and the epigenetics of human health. Annual Review of Anthropology, 45, 233-249.

11. Glad, C. A., Andersson-Assarsson, J. C., Berglund, P., Bergthorsdottir, R., Ragnarsson, O., & Johannsson, G. (2017). Reduced DNA methylation and psychopathology following endogenous hypercortisolisma genome-wide study. Nature: Scientific Reports, 7, 44445.

12. Wein, H. (2010). Stress Hormone Causes Epigenetic Changes. NIH Research Matters. https://www.nih.gov/news-events/nih-research-matters/stress-hormone-causes-epigenetic-changes

13. Rubinow, D. R., Roca, C. A., Schmidt, P. J., Danaceau, M. A., Putnam, K., Cizza, G., & Nieman, L. (2005). Testosterone suppression of CRH-stimulated cortisol in men. Neuropsychopharmacology, 30(10), 1906-1912.

14. Rosen, R. C. (2001). Psychogenic erectile dysfunction: classification and management. Urologic Clinics of North America, 28(2), 269-278.

15. Bond, D. S., Lyle, R. M., Tappe, M. K., Seehafer, R. S., & DZurilla, T. J. (2002). Moderate aerobic exercise, Tai Chi, and social problem-solving ability in relation to psychological stress. International Journal of Stress Management, 9(4), 329-343.

16. Hsu, Y. C., Tsai, S. F., Yu, L., Chuang, J. I., Wu, F. S., Jen, C. J., & Kuo, Y. M. (2016). Long-term moderate exercise accelerates the recovery of stress-evoked cardiovascular responses. Stress, 19(1), 125-132.

17. Yassin, A. A., & Doros, G. (2013). Testosterone therapy in hypogonadal men results in sustained and clinically meaningful weight loss. Clinical Obesity, 3(3-4), 73-83.

18. Craig, B. W., Brown, R., & Everhart, J. (1989). Effects of progressive resistance training on growth hormone and testosterone levels in young and elderly subjects. Mechanisms of Ageing and Development, 49(2), 159-169.

19. Osterberg, E. C., Bernie, A. M., & Ramasamy, R. (2014). Risks of testosterone replacement therapy in men. Indian journal of urology: IJU: journal of the Urological Society of India, 30(1), 2.

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Dear Abby: Overworked husband likes his choices – Manistee News Advocate

A man can't stop working.

A man can't stop working.

Photo: Kaisersosa67/Getty Images/iStockphoto

A man can't stop working.

A man can't stop working.

Dear Abby: Overworked husband likes his choices

DEAR ABBY: I have a wonderful husband of almost 20 years and two teenage children. My husband is incredibly hardworking in his stressful career and has provided a very comfortable life for us. The trouble is, he puts work ahead of any self-care. He works most waking hours, doesn't eat well, exercises rarely, is overweight the list goes on. When I ask/encourage/nag him to make positive lifestyle choices, he reminds me of the life insurance he has and turns it around on me and says I am stressing him.

Abby, I love my husband, and I worry that this will cut his life and our life together short. Can you help?

Beside myself with worry

DEAR BESIDE YOURSELF: I wish I could wave a magic wand and make your husband receptive to what you are trying to do for him. But until he's ready to address these issues and do something about them, nothing will change.

If he enjoys his career and takes pride in the fact that you and your children are and will be provided for, then he's living the life he has chosen for himself. This does not mean you must give up entirely suggesting healthy lifestyle choices, but perhaps do it a little less often and in terms of activities he might enjoy.

DEAR ABBY: After a long and successful life, my uncle recently passed away. His wife is my mother's sister. During one of our phone calls, she told me she and my cousins had written his obituary and that it would be published soon. To my shock and dismay, I located the obituary and discovered that my sister and I were not mentioned as his niece and nephew. I am still terribly hurt. Why would they do this?

My sister and I grew up spending every major holiday and birthday with my uncle. The obituary did include his other niece and nephew who live on the opposite side of the country and kept in touch only with an occasional phone call and holiday card. I included my cousins in my parents' and sister's obituaries, all of whom have passed in the last few years.

I feel that I must address this with them, but I don't want to add to the pain they are going through while they mourn their loss. I now dread attending the memorial because I'm worried friends of our family may bring it up, and I won't know what to say.

Hurt nephew in Illinois

DEAR NEPHEW: Even when a death is expected, many people go into a state of shock, which interferes with their ability to sequence facts. It is entirely possible that the obituary was written when your aunt and cousins weren't thinking straight, which is why you were omitted. If someone brings it up at the memorial which I doubt will happen rather than nurse hurt feelings, I hope you will point out that the family, including you, is grieving. Period.

DEAR ABBY: How do you politely ask a neighbor to mow his lawn at reasonable times of the day? Mine seems to be doing it three days a week and always when we want to enjoy our backyard.

Trying to relax

DEAR TRYING: If you are on speaking terms with this neighbor, explain that the noise from his lawnmower interferes with your ability to enjoy your backyard and ask POLITELY if he could schedule it at another hour of the day. If he is a good neighbor, he should be willing to accommodate you.

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Dear Abby: Overworked husband likes his choices - Manistee News Advocate

Courtney A. Mullings’s newly released My God, It’s Cancer brings an inspiring journey of seeking God along the struggles of dealing with cancer – PR…

MEADVILLE, Pa. (PRWEB) August 04, 2020

My God, Its Cancer: My epic journey with a late-stage terminal cancer, sustained by outrageous faith for healing through grace: a strong testimony of Gods powerful healing grace in the life of a man who constantly faces the darkness and the loss of hope. My God, Its Cancer: My epic journey with a late-stage terminal cancer, sustained by outrageous faith for healing through grace is the creation of published author Courtney A. Mullings, a former telecommunications consultant and devout Christian. He is traveling on an intense hope-filled, faith-based journey as he copes with the effects of his cancer.

Mullings shares, Life is not fair! Imagine going steadfastly through life, enjoying a healthy lifestyle, playing by the rules and obeying the Word of God, only to be blindsided by a terminal cancer diagnosis in the prime of your life.

In My God, Its Cancer, Courtney Mullings shares the inspiring story of the medical, emotional and spiritual struggles encountered on his journey with what science defines as an incurable cancer. His exceptional life moments with the disease are encapsulated and documented to reveal episodes of struggles with guilt and unworthiness, and how he coped with the multiple failures and setbacks through his faith.

Travel with him to experience how he continuously sought God as his refuge and remained fervently faithful that he would receive complete healing through Gods grace. Courtneys faith gave him indomitable strength. Learn how his outrageous faith reinforces the concept of transcendental hope beyond what can be seen or reasoned through our natural senses, but as he has experienced from God.

By telling his story, he hopes to inspire, motivate and reach the many people who want to believe there is hope for their individual situations, but may be challenged by the realities of current circumstances. His story will help you to appreciate that life will inevitably present daunting challenges, but you have a choice in how you respond. God provides us with unlimited solutions through grace to address all of lifes challenges. What level of faith are you willing to invest in God for your best outcome?

Published by Christian Faith Publishing, Courtney A. Mullingss new book is a profound and personal life story designed to share and inspire people with hope in the events of challenges. Here, the author aims to encourage the readers to appreciate the goodness and blessedness of life amidst the struggles.

View a synopsis of My God, Its Cancer: My epic journey with a late-stage terminal cancer, sustained by outrageous faith for healing through grace on YouTube.

Consumers can purchase My God, Its Cancer: My epic journey with a late-stage terminal cancer, sustained by outrageous faith for healing through grace at traditional brick & mortar bookstores, or online at Amazon.com, Apple iTunes store, or Barnes and Noble.

For additional information or inquiries about My God, Its Cancer: My epic journey with a late-stage terminal cancer, sustained by outrageous faith for healing through grace, contact the Christian Faith Publishing media department at 866-554-0919.

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Courtney A. Mullings's newly released My God, It's Cancer brings an inspiring journey of seeking God along the struggles of dealing with cancer - PR...

Are very long-lived trees immortal and what can they teach humans? – ABC News

While humans are all too familiar with the ravages of getting older, many trees seem to handle ageing a lot better.

Certain trees can live for thousands of years and appear to be immortal.

But not everyone is convinced these old timers can escape death due to old age.

Regardless, could humans with their relatively puny lifespans have something to learn from these ancient trees? Some scientists think so.

Establishing how old the oldest living tree is depends a bit on which plants are in the running for the title.

You could argue that Australia's Wollemi pine, which has been cloning itself for more than 60 million years, deserves the title. But that's kind of cheating because this involves multiple stems growing from the one rootstock.

This is why the oldest tree in the world is generally regarded as a single-stemmed bristlecone pine called Pinus longaeva.

This species can live to around 5,000 years and does well where most other plants cannot even grow in rocky, dry, high-altitude areas in the United States.

What's amazing is that scientists have not so far been able to show that getting older directly affects the health of such millennial trees, plant biologist Sergi Munne-Bosch from the University of Barcelona says.

It's because of this, some say these trees are essentially immortal.

But in a recent article, Professor Munne-Bosch argues that it's likely even ancient trees could die from old age assuming something else doesn't kill them first.

He emphasises that there's a difference between ageing, which is about how long an organism has lived, and age-related deterioration, which is referred to as senescence.

"Just because we can't track senescence in long-lived trees doesn't mean they are immortal."

Professor Munne-Bosch points to recent research on centuries-old Ginkgo biloba trees that found no evidence of senescence.

The study was the first to look for evidence of age-related changes in cells of the cambium, a layer just beneath the bark that contains cells that can produce new tissue throughout the plant's life.

It confirmed the long-lived trees, which in this case were up to 667 years old, were just as healthy as younger ones says Professor Munne-Bosch.

"They grow very well, they produce seeds, they produce flowers, so they are healthy."

He points out that even though a 667-year-old tree seems old when compared to a human, it is relatively young for a ginkgo.

"This species can live for more than two millennia."

Professor Munne-Bosch argues that the ginkgo researchers' data shows that older trees had thinner vascular tissue and that this hints at possible age-related deterioration that would be more obvious in even older trees.

Yet despite this deterioration, he says these trees are more likely to die from insects, disease, fire, drought or loggers, than old age.

"For a species that can live for millennia, aging is not really a problem in evolutionary terms because they are much more likely to die of something else."

The problem is there are so few of these long-lived trees that it's hard to get the data to know for certain whether they can die of old age.

"We cannot prove it either way," Professor Munne-Bosch says, adding that age-related deterioration is likely to happen in these trees at such a different pace compared to in humans.

"For a Ginkgo biloba, six centuries is not as physiologically relevant as it is to us."

Brenda Casper, a professor of biology at the University of Pennsylvania says it's not clear that the changes found in the older Ginkgo biloba trees were necessarily detrimental to the tree.

But she agrees the low number of millennial trees makes it hard to study their longevity.

"It's difficult to find statistical evidence for senescence."

Even if there were enough trees, she says some of the age-related deterioration may be hard to detect, or we may not know what to look for.

"It's not just internal physiology per se but it's the interaction of the tree with its environment."

For example, she says it would be hard to measure whether age had made a tree more susceptible to disease, or less structurally sound so it's more likely to fall over in a windstorm.

Even if the jury is out on whether millennial trees are immortal, some experts say their longevity could be inspirational for medical research.

Professor Munne-Bosch says such trees can draw on a bag of tricks to help them "postpone death".

First is having a simple body plan with modular-like branches and roots. This means they can compartmentalise any damaged or dead roots or branches and work around them.

"They can lose part of leaves or roots and continue to be healthy..

And he says although 95 per cent of the trunk of a tree might be dead, the living cambium just beneath the bark is "one of the secrets of longevity" in trees.

Millennial trees have used the combination of these features to their best advantage and Professor Munne-Bosch says these tricks are providing a model for scientists researching the negative effects of ageing.

"Imagine if we could regenerate our lungs or circulatory system every year, we would be much healthier than we are."

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Professor of biomedical engineering at the University of New South Wales, Melissa Knothe Tate is one researcher who is inspired by millennial trees.

"They have units and if one unit breaks you can replace it with another unit."

Only a small percentage of an individual long-lived tree may be alive, but she argues it's all about survival of the cells that are able to regenerate the tree.

"Those that survive best, survive longest."

"Millennial trees are the best survivors because they've seen a lot."

While a tree and a human might seem worlds apart, Professor Knothe Tate sees the similarities, pointing to the role of stem cells in maintaining bones in humans.

She says cells add new layers to bone, like tree rings, to increase girth and when bone is injured, stem cells quickly help repair it.

"We're constantly renewing our bones and trees do something similar."

Professor Knothe Tate says she is using stem cells and new biomaterials that emulate tree cambium, to create replacement tissue in the lab, and has several patents for the work.

"I think about plants a lot when I'm up in the mountains and amongst the trees."

Professor Knothe Tate, who draws on her training in philosophy, biology and mechanical engineering for her work, sees other similarities that can inspire research.

For example, she likens the human brain to the network of roots and branches that helps a tree remain resilient if one part is damaged, another part can sometimes take up the slack.

"As parts of the brain are injured or die, it's remarkable what functionality we can retain,

"If we knew which of the brain's networks were essential for certain functions, we may be able to grow them."

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Professor Knothe Tate also set up a science education project for girls that explores the parallels between the biomechanics of trees and bones. It was inspired by her observation of how huge trees sway like a blade of grass in the wind.

She has high hopes for the potential of regenerative medicine research that draws on knowledge from other disciplines like plant biology.

"Then we can then start to think about making ourselves immortal."

Plant biologist Professor Munne-Bosch is also enthusiastic.

"The future of medicine is very similar to what has evolved in millennial trees."

But while regenerating tissues will help humans live much longer, he doubts we will ever be immortal.

"It won't be forever, because we are more likely to die of something else, whether it be an accident or a pandemic."

Get all the latest science stories from across the ABC.

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Are very long-lived trees immortal and what can they teach humans? - ABC News

Jessica Alba’s Healthy Living Tips – OK!

Being a successful actress and owner of the beauty store The Honest Company can be a daunting task for a mother of three, but Jessica Alba shares her nine tips on how to get ahead in life and health.

Start Strong

The 39-year-old star fuels up for the day ahead with a healthy and hearty breakfast. She alternates between avocado toast with poached eggs (her fav!) and smoothies.

Recently I started making this shake using vegan protein powder, matcha green tea powder, a banana, coconut water and ice, shared Alba. I drink it before a workout, and it doesnt make me feel too full.

Make A Playlist

The right tunes help you get and stay in the zone. For Alba, that means lots of Drake, Jay-Z, and Kanye West.

And I have some new artists that Ive been listening to a lot, she noted, adding, I like any kind of West Coast rapper usually more hip-hop and rap and less pop music.

JESSICA ALBA CLAIMS SHE STOPPED EATING IN HER 20S SO MEN WOULD STOP LUSTING AFTER HER VOLUPTUOUS BODY

Cut Back On Carbs & Sugar

With exercise, I get a little more toned and I definitely feel stronger, but my diet is much more important if Im trying to slim down, she explained. The Honest Company founder avoids dairy, gluten and processed foods. I try to stick to a diet thats low in sugar and carbs and high in lean proteins and vegetables.

Keep It Interesting

Variety is the spice of life for the actress, who mixes up her workouts, so she never gets bored. Her go-to classes include yoga sculpt (which combines traditional hot yoga with light weights and cardio) and spinning. I like high-intensity workouts and I like moving around a lot, she confessed. I dont like a lot of repetition.

Snack Away

When shes hungry between meals, Alba noshes on light-but-tasty fare like veggies with hummus and popcorn. I love popcorn, she gushed. I eat that at the office every day. I make it with Himalayan sea salt and coconut oil. Yum!

Get Some Me Time

At the end of a long day, Alba relaxes and centres herself with some good old-fashioned self-care. After some quality time with her kids, I enjoy a bath with a glass of wine and a book, she shared. The Sin City star caps things off with some serious beauty pampering. I often add a face mask and a hair mask as part of my weekly wind-down routine, she added. When youre doing something for yourself, its a nice reminder that you matter.

JESSICA ALBA GETS THREE NEW TATTOOS IN HONOR OF HER KIDS & FANS ARE NOT IMPRESSED SEE THE PICS!

Know Yourself

Alba said that the benefits of exercise are [more] mental than physical for her. But that doesnt mean she doesnt appreciate what her bodys capable of. If I want to go on a hike or a bike ride or go for a swim, she said, I know my body will do everything I tell it to.

Hydrate!

How does she get that glow? I think staying hydrated is really important, said the L.A.s Finest actress, whos a huge fan of coconut water.

Be Practical

Alba is totally dedicated to fitness. But the busy mom of three she shares Honor, 12, Haven, 8, and Hayes, 2, with husband Cash Warren is also realistic about what she can squeeze into her hectic schedule. If I work out four times, I consider it a successful week, she said. But its typically more like two to three days a week because thats what I have time for. Its cleverly working!

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Jessica Alba's Healthy Living Tips - OK!

Stemsation(TM) Third Product – StemFlex(TM) Now in Distribution Enters the Fast-Growing $9 Billion CBD Market – Press Release – Digital Journal

BOCA RATON, FL / ACCESSWIRE / August 4, 2020 / StemSation International, Inc. (OTC PINK:STSN) - a pioneer in the emerging category of dietary supplements called Stem Cell Nutrition, announces that its third product, a fast-acting and exclusive topical formula with CBD named StemFlex for joint and muscle health is through production and inventory is now for sale in the United States through its Independent Wellness Advocates. https://www.stemsation.global/www/en/us/item/10027/Stemflex-stemflex/.

A synergistic companion product to the recently released ProStem PSPTM dietary supplement for joint and muscle health, this topical formula in combination with ProStem PSP brings a novel "inside out" wellness system unmatched in the marketplace. StemFlex is expected to be available for sale in Europe in September.

Developed by Dr. Mira Gadzala, a highly respected PhD and board-certified Alternative Medical Practitioner, this innovative product utilizes the most recent research advancements of all-natural, organic plant and essential oil extracts to create a fast-acting, highly absorbable, non-greasy, safe, and powerful formula. Dr. Gadzala is StemSation's Chief Scientific Officer.

Dr. Mira Gadzala commented, "We are excited to offer our third innovative, fast-acting, and exceptional quality natural product - a topical formulation, that supports joint and muscle health in a multidimensional way. The combination of powerful polyphenolic compounds, antioxidants, glyconutrients, MSM, fatty acids, and other natural compounds in StemFlex forms a unique nutritional platform and provides powerful natural support and nourishment for the connective tissue and overall joint and muscle function and mobility. With CBD included, it also helps to support special receptors present in your body known as the endocannabinoid system (ECS). The ECS is involved in a great number of important functions and processes in the body, including pain perception, bone and joint health, inflammation, and stress responses, sleep, and much more. Recent studies have intriguingly suggested the existence of a functional ECS in the skin and implicated it in various biological processes. We follow these new and exciting research findings."

The global market for cannabidiol (CBD) is growing rapidly, estimated to reach $9.2 billion in 2020. The market has consistently grown over the last several years and is expecting to exceed more than $23.6 billion by 2025 at an impressive CAGR of 22.2% in the given forecast period, as reported by Grandview Research December, 2019 (https://www.grandviewresearch.com/industry-analysis/cannabidiol-cbd-market). Hemp-derived CBD-infused personal care products are rising significantly in demand.

Bone health has become a major public health concern across the globe. According to statistics, about 75 million people in the United States, Europe, and Japan have bone health concerns, and the population with bone and joint health issues is growing at alarming rates, as more baby boomers enter their 60's and early 70's globally. Joint health used to predominantly be associated with older people, but not anymore. Baby boomers of today, as well as younger generations, are concerned about their physical fitness, mobility, and joint and muscle health.

All ingredients in StemFlex are backed by strong science, have been extensively studied, and clinically proven for efficacy and safety. They come from all-natural and organic sources found in nature. StemFlex has been made according to high organic standards, in a US facility that is certified to the best organic standards: USDA NOP and NSF ANSI/305. StemFlex does not contain any synthetic additives or preservatives.

Its unique combination of ingredients works as a team and helps to nourish, support, and maintain joint and muscle health, flexibility, mobility, while soothing aches and stiffness from overexertion from everyday activities, exercise, and aging.

StemSation is a company with a long-term 'health mission', ambitious research goals, and innovative, holistic approaches to health & wellness, and healthy longevity. Our product line shows a new pathway to wellness.

ABOUT DR. MIRA GADZALA

Dr. Mira Gadzala has three decades of experience in formulating natural dietary supplement products, and is the founder of BioCell Rejuvenation, a consulting, research and development company in the field of alternative health and vitamins. Her most recent work involves researching and formulating advanced stem cell nutrition products. Dr. Gadzala holds a PhD degree in Holistic Nutrition, a Master of Sciences (MSc) in Cell Biology and pursued a doctoral degree in Cell Biology. She has been granted a full Board Certification as an Alternative Medical Practitioner (AMP) by the American Alternative Medical Association and holds two prestigious designations: Registered Orthomolecular Health Practitioner (ROHP) and Registered Nutritional Consultant Practitioner (RNCP). Dr. Gadzala is a member of several health organizations, including the American Alternative Medical Association and International Organization of Nutritional Consultants (Canada, USA), and has served on the Advisory Board of the "Cellular Health Communication" magazine (US), Stemtech's Scientific Advisory Board, and as a primary member of the Institutional Animal Care and Use Committee (IACUC) at a California-based vitamin research company.

ABOUT STEMSATION INTERNATIONAL, INC.

StemSation International, Inc. (OTC "STSN") develops, manufactures and distributes natural wellness products that support the stem cell and endocannabinoid systems in the human body through using a direct selling model in which Independent Wellness Advocates ("IWAs") advertise and sell its products directly to consumers. StemSation is headquartered in Boca Raton, Florida and its website can be located at http://www.stemsation.global.

SAFE HARBOR STATEMENT

This press release contains forward-looking statements that can be identified by terminology such as "believes," "expects," "potential," "plans," "suggests," "may," "should," "could," "intends," or similar expressions. Many forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from any future results implied by such statements. These factors include, but are not limited to, our ability to continue to enhance our products and systems to address industry changes, our ability to expand our customer base and retain existing customers, our ability to effectively compete in our market segment, the lack of public information on our company, our ability to raise sufficient capital to fund our business, operations, our ability to continue as a going concern, and a limited public market for our common stock, among other risks. Many factors are difficult to predict accurately and are generally beyond the company's control. Forward-looking statements speak only as to the date they are made, and we do not undertake to update forward-looking statements to reflect circumstances or events that occur after the date the forward-looking statements are made.

FOR INFORMATION, PLEASE CONTACT:

Nicholas B. Panza, Vice-PresidentStemsation International, Inc.7777 Glades RoadSuite 203Boca Raton, FL 33434npanza@stemsationusa.com (561) 245-7454

SOURCE:StemSation International, Inc.

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Stemsation(TM) Third Product - StemFlex(TM) Now in Distribution Enters the Fast-Growing $9 Billion CBD Market - Press Release - Digital Journal

Nine Cambridge researchers among this year’s Royal Society medal and award winners – Mirage News

He is one of the 25 Royal Society medals and awards winners announced today, nine of whom are researchers at the University of Cambridge. The annual prizes celebrate exceptional researchers and outstanding contributions to science across a wide array of fields.

President of the Royal Society, Venki Ramakrishnan, said:

The Royal Societys medals and awards celebrate those researchers whose ground-breaking work has helped answer fundamental questions and advance our understanding of the world around us. They also champion those who have reinforced sciences place in society, whether through inspiring public engagement, improving our education system, or by making STEM careers more inclusive and rewarding.

This year has highlighted how integral science is in our daily lives, and tackling the challenges we face, and it gives me great pleasure to congratulate all our winners and thank them for their work.

Sir Alan Fersht FMedSci FRS, Emeritus Professor in the Department of Chemistry and former Master of Gonville and Caius College, is awarded the Copley Medal for the development and application of methods to describe protein folding pathways at atomic resolution, revolutionising our understanding of these processes.

Most of us who become scientists do so because science is one of the most rewarding and satisfying of careers and we actually get paid for doing what we enjoy and for our benefitting humankind. Recognition of ones work, especially at home, is icing on the cake, said Sir Alan. Like many Copley medallists, I hail from a humble immigrant background and the first of my family to go to university. If people like me are seen to be honoured for science, then I hope it will encourage young people in similar situations to take up science.

As the latest recipient of the Royal Societys premier award, Sir Alan joins an elite group of scientists, that includes Charles Darwin, Albert Einstein and Dorothy Hodgkin, and more recently Professor John Goodenough (2020) for his research on the rechargeable lithium battery, Peter Higgs (2015), the physicist who hypothesised the existence of the Higgs Boson, and DNA fingerprinting pioneer Alec Jeffreys (2014).

Professor Barry Everitt FMedSci FRS, from the Department of Psychology and former Master of Downing College, receives the Croonian Medal and Lecture for research which has elucidated brain mechanisms of motivation and applied them to important societal issues such as drug addiction.

Professor Everitt said: In addition to my personal pride about having received this prestigious award, I hope that it helps draw attention to experimental addiction research, its importance and potential.

Professor Herbert Huppert FRS of the Department of Applied Mathematics and Theoretical Physics, and a Fellow of Kings College, receives a Royal Medal for outstanding achievements in the physical sciences. He has been at the forefront of research in fluid mechanics. As an applied mathematician he has consistently developed highly original analysis of key natural and industrial processes. Further to his research, he has chaired policy work on how science can help defend against terrorism, and carbon capture and storage in Europe.

In addition to the work for which they are recognised with an award, several of this years recipients have also been working on issues relating to the COVID-19 pandemic.

Professor Julia Gog of the Department of Applied Mathematics and Theoretical Physics and a Fellow of Queens College, receives the Rosalind Franklin Award and Lecture for her achievements in the field of mathematics. Her expertise in infectious diseases and virus modelling has seen her contribute to the pandemic response, including as a participant at SAGE meetings. The STEM project component of her award will produce resources for Key Stage 3 (ages 11-14) maths pupils and teachers exploring the curriculum in the context of modelling epidemics and infectious diseases and showing how maths can change the world for the better.

The Societys Michael Faraday Prize is awarded to Sir David Spiegelhalter OBE FRS, of the Winton Centre for Centre for Risk and Evidence Communication and a Fellow of Churchill College, for bringing key insights from the disciplines of statistics and probability vividly home to the public at large, and to key decision-makers, in entertaining and accessible ways, most recently through the COVID-19 pandemic.

The full list of Cambridges 2020 winners and their award citations:

Copley Medal

Alan Fersht FMedSci FRS, Department of Chemistry, and Gonville and Caius College

He has developed and applied the methods of protein engineering to provide descriptions of protein folding pathways at atomic resolution, revolutionising our understanding of these processes.

Croonian Medal and Lecture

Professor Barry Everitt FMedSci FRS, Department of Psychology and Downing College

He has elucidated brain mechanisms of motivation and applied them to important societal issues such as drug addiction.

Royal Medal A

Professor Herbert Huppert FRS, Department of Applied Mathematics and Theoretical Physics, and Kings College

He has been at the forefront of research in fluid mechanics. As an applied mathematician he has consistently developed highly original analysis of key natural and industrial processes.

Hughes Medal

Professor Clare Grey FRS, Department of Chemistry and Pembroke College

For her pioneering work on the development and application of new characterization methodology to develop fundamental insight into how batteries, supercapacitors and fuel cells operate.

Ferrier Medal and Lecture

Professor Daniel Wolpert FMedSci FRS, Department of Engineering and Trinity College

For ground-breaking contributions to our understanding of how the brain controls movement. Using theoretical and experimental approaches he has elucidated the computational principles underlying skilled motor behaviour.

Michael Faraday Prize and Lecture

Sir David Spiegelhalter OBE FRS, Winton Centre for Risk and Evidence Communication and Churchill College

For bringing key insights from the disciplines of statistics and probability vividly home to the public at large, and to key decision-makers, in entertaining and accessible ways, most recently through the COVID-19 pandemic.

Milner Award and Lecture

Professor Zoubin Ghahramani FRS, Department of Engineering and St Johns College

For his fundamental contributions to probabilistic machine learning.

Rosalind Franklin Award and Lecture

Professor Julia Gog, Department of Applied Mathematics and Theoretical Physics, and Queens College

For her achievements in the field of mathematics and her impactful project proposal with its potential for a long-term legacy.

Royal Society Mullard Award

Professor Stephen Jackson FMedSci FRS, Gurdon Institute, Department of Biochemistry

For pioneering research on DNA repair mechanisms and synthetic lethality that led to the discovery of olaparib, which has reached blockbuster status for the treatment of ovarian and breast cancers.

The full list of medals and awards, including their description and past winners can be found on the Royal Society website: https://royalsociety.org/grants-schemes-awards/awards/

Adapted from a Royal Society press release.

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Nine Cambridge researchers among this year's Royal Society medal and award winners - Mirage News

Nutrition Check: Want to feel great? It’s all in the plate! – Florida NewsLine

By Kristen Hicks-Roof PhD, RDN, LDN and Marissa Schwam BSmail@floridanewsline.com

Wanting to obtain a healthy lifestyle has become quite popular over the last decades; however, there is a lot of misleading information that people have been utilizing in order to obtain their goal of becoming healthier. There are countless fad diets that promise quick fixes, rapid weight loss, and even detoxification. The truth is, obtaining a healthy lifestyle doesnt mean you need to restrict food groups or starve yourself to lose weight. Its all about how you build your plate. Every plate we make is a building block for a healthier lifestyle, so it is important that we include all food groups as a part of our meals and snacks. Here are some easy steps to help you build your plate and obtain the goal of a healthier you.

1. Aim to make half of your plate full of fruits and vegetables. Fruits and vegetables are full of nutrients that support healthy functioning of your brain, cells, skin, and everything in between. Try to include all different colors such as orange, red, purple, white and green.

2. Dont forget whole grains. Try to make at least half of your grains whole. Whole grains are a great source of B vitamins and natural fiber, which helps reduce cholesterol and helps keep you regular. Try some ancient whole grains including barley, bulgur, quinoa, sorghum, or wild rice.

3. Protein should take up the last quarter of your plate. Choosing lean or plant proteins will help you reduce your intake of saturated fat, which has been shown to increase your risk for heart disease and strokes. Lean or plant proteins include chicken, turkey, nuts, beans, tofu, and even some cuts of beef such as flank or strip steak.

4. Switch it up by trying to add in some new foods to your regular routine. Keep mealtime fun by picking out foods you or your family have never tried before like chia seeds, lentils, brussel sprouts, cauliflower, or edamame.

5. Dont ignore your cravings. If you have a sweet tooth, you can always satisfy this craving in a healthy way. You can always do fresh fruit parfait with whipped topping, yogurt or some mini white chocolate morsels. If you like hot desserts, then you can try baking apples or peaches.

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Nutrition Check: Want to feel great? It's all in the plate! - Florida NewsLine

I Tried ‘All Out’ for Two Weeks and I’m Canceling My Gym Membership – Men’s Health

I'm not gonna lie, once lockdown hit I traded-in dumbbells for Doritos. And slowly but surely, I watched those lockdown el-bees stack-up on the scale. I never thought I'd say this, but I really do miss the gym. It was a tough adjustment going from working out 3-5 days a week at the gym to suddenly, um, well... not. Now, I'm not going to sit here and pretend that I was a total gym rat B.Q. (before quarantine). My world has never revolved around fitness, but I'm all about maintaining a healthy lifestyle. You see, I'm a content creator so I spend a lot of time sitting at my desk writing and editing various projects. The gym was a place where I could get up, get out, throw on a juicy true-crime podcast, and sweat my stress away. Without it, I felt I had really fallen out of my fitness flow but after trying out some sessions on Men's Health's new app, All Out Studio, I'm convinced that I won't be going back to the gym.

There are a ton of different fitness apps out there, and yes, Ive tried quite a few from the gimmicky, make me look like [insert superhero name here] in 60 days to the overpriced (and underwhelming) trendy fitness apps Ive been there, done that. And they are either too expensive or they just really didnt hold my interest. Alas, I decided to give All Out Studio a shot.

The app gives you access to an entire library of premium workouts and fitness programs designed by experts and developed by Men's Health, Women's Health, Runner's World, and Prevention. It's divided into different sections so you can choose to "Go Hard," "Go Light," or even "Go All Out."

It also allows you to browse programs curated through specific brands like Men's Health, Runner's World, Women's Health, Cosmo, and Prevention. And these aren't just one-off classes they've got full-blown programs that are structured to provide proven results. It's like having your pick of personal trainers right at your fingertips. You can tailor the experience to fit your #bodygoals. While skimming the app for the first time, some of the programs that stuck out to me were:

While I was all about the clutch buffet of content, I'm the type of person that's all about the price tag. There are two subscription routes you can take both of which come with a free one-week trial. Option one allows you to go month-to-month for $14.99/month equaling out to less than 50 cents per day.

Option two is an annual subscription for $89.99. Let's break down that annual figure, shall we? At $89.99/year, that's approximately $7.50/month, and TBH I spent more than that on my coffee and breakfast sandwich this morning. But wait, if we break that number down even further, $7.50/month comes down to approximately 25 cents per day. Um, excuse me. What?! I've met gumballs more expensive than that.

For most of the sessions, it appears that a mat and dumbbells will do the trick so a fully equipped at-home gym isn't necessary. Theres no need here to splurge on expensive pieces of exercise equipment thatll probably end up becoming a dusty catch-all for your dirty clothes.

The app is available for download on iOS and Android, but it can also be streamed via Apple TV, Roku, or Fire TV which I liked because you can watch it on the big screen and really immerse yourself in the class. Plus, it's a rather seamless transition from your phone to TV so if you start a class on one device, you can easily pick up right where you left off on the other.

Photo Courtesy of Alex Aronson

Now that I had done all the preliminary leg work [pun sorta intended], it was time to stop procrastinating and actually get to working-out. Since the gyms have been closed for a few months now, I was a little anxious to really get back into it, so I decided to start out light and ease my way back into beast mode I hate that I just said that, but you get the idea.

I quickly discovered that the app provides a wide selection of quality fitness content at a bargain bin price.

Peep the app in the video below.

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I decided to check-out "Anarchy 10" in the Men's Health section and did a chest & back session with Andy Speer. There are four videos under this program each hovering around the 10-minute mark and they're designed to give you brief yet intense workouts. I knew the following day my chest was going to feel it, and, yeah, I was right. Speer came, conquered, and delivered with his "little" ten-minute session. It was a good way to get my feet wet.

What next?

As a consequence for the mass intake of pizza and wine I have consumed during this lockdown, I decided that a program called All Out HIIT sounded like the proper punishment. And it was. The program consists of six videos that focus on 15-minute high-intensity interval training workouts that combine cardio conditioning and a strength workout in one. For the total-body session, jumping jacks, burpees, squats, lunges, push-ups, and planks were all present.

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After dipping my toe into a few of the offerings, I decided I wanted to fully commit to a program, so I landed on Six Week Sweat. There are ten classes led by Sean Garner. Each one lasts about 30-minutes, and I must say, the program lives up to its name. By the end of a session, I am usually drenched and totally feeling it. There is also a handy workout guide that breaks-down the classes into an actionable schedule. Lets just say, Mr. Garner is now my new trainer, and I fully intend to see the full six-week program through.

(Stream 200+ workouts today at All Out Studio)

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I Tried 'All Out' for Two Weeks and I'm Canceling My Gym Membership - Men's Health

After losing 235 pounds, Houstonian commits to the marathon of healthy living – Houston Chronicle

Amer Ismail could hold the excess skin on his stomach like a swaddled baby.

The skin weighed more than 15 pounds, and it threw off his balance when he exercised. When he was training for his first marathon, his stomach flap would routinely hit his torso and left him feeling sore.

Finding clothes that fit was the hardest part for the 27-year-old Houstonian who has dropped 235 pounds in four years.

There are no clothes for loose skin either you have your pants under your belly or you have to tuck the skin under your pants, Ismail said. It got caught, and it was constantly pinched. I ended up with lots of cuts and scrapes. It was unavoidable.

After loose-skin surgery in May, Ismail can finally see the progress he has made since he began his healthy lifestyle. The surgery didnt change the amount of work he had done, but he could finally see the results.

On HoustonChronicle.com: Losing nearly half his bodyweight, Houston man has no plans to stop

He now fits in a Large size T-shirt. And when he puts the shirt on, it falls straight down rather than getting caught on the skin around his belly. He cant grab his stomach at all anymore.

Standing at 6 foot 3 inches and 235 pounds, Ismail remembers what it was like to be close to 500 pounds in his early 20s. All the jokes and unfriendly looks are gone, and he feels just like everyone else.

Hes just a guy whos half the guy he used to be.

Its not typical for a person to lose so much weight they require skin removal unless they had bariatric surgery or another type of weight loss procedure, said Dr. John LoMonaco, a plastic surgeon based in Clear Lake who performed Ismails surgery.

These people have great stories to tell; its the reason I do what I do, LoMonaco said. If youre into these peoples journeys to fight the disease that was destroying their quality of life, you know its not a vanity surgery. He just wanted to be normal, and hes still fighting to keep that weight off.

The last year has been full of incredible highs and unexpected lows for Ismail.

After months of training, he ran his first Chevron Houston Marathon in January, finishing in 6 hours, 8 minutes and 6 seconds.

He hated the act of running while he was doing it. He had never really run before, so every week was a new unlocked achievement. For months, he ran four times a week and lifted weights on off days; some weeks, he pulled two-a-day workouts at the Memorial Hermann Ironman Sports Medicine Institute.

He went from barely being able to run two miles to finishing a full 26.2 miles within six months of training. It was a slow, but constant progression.

The hardest part was surviving all the weather conditions; it would be so hot, I felt like I was drowning in the humidity, Ismail said. It was tough because I felt like there were weeks with no progress, and that I was stalling. But if you keep doing it, keep trusting yourself, eventually you see how far youve come.

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Ismail took the high of his marathon finish into his next athletic endeavor: Brazilian Jiu Jitsu. In February, he tore his ACL during a regular takedown move while sparring with another person.

The injury has pushed back his running goals for 2020. But he hopes to get the OK to start running again soon. He has been exercising twice-a-week with Blaine Schmidt, strength and conditioning coach with Athlete Training in Health, an affiliate of the Memorial Hermann Ironman Sports Medicine Institute.

To go through all the stuff he went through and to keep the same attitude he had thats something you dont see a whole lot nowadays, Schmidt said. He had his skin surgery all set before he had that injury and that was a little setback. But he was still straightforward on his goals. Nothing was going to stop him.

This was Ismails second ACL surgery in the last four years. He has also had a spleen rupture, which needed to be surgically repaired and resulted in a hernia. Then, he had the first part of his skin removal surgery in May; hell have another surgery next year.

I am so done with surgeries; I want to retire, he said.

The knee surgery coincided with the beginning of the novel coronavirus pandemic, which gave him a much-needed reason to slow down and recover.

Thats where his commitment to healthy eating or as he calls it, boring eating comes into play.

During the pandemic, Ismail stuck to the same four or five dishes, usually including lean chicken, rice with sweet potatoes and a salad mix. Sometimes, he opts for ground turkey or steak. Every now and then, he eats a slice of chocolate cake or buys a chocolate bar.

He estimates that he eats about a pound of meat every day, especially on the days he works out. Lean protein satisfies his hunger, he said, after years of a carbohydrate-loaded diet of pizza, cheese burgers and fatty junk food.

Plastic surgeons have to figure out whether a person has overcome his negative relationship with food before committing to a weight-loss or skin-removal surgery, LoMonaco said. Plastic surgery does not cure food addiction, he added.

Many times, patients will develop a new addiction to exercise or a healthy lifestyle and they can be compulsive about their routine, LoMonaco said. (Ismail) had done a ton of research and slowly and steadily progressed on his weight loss. He wasnt doing a fad diet or a quick pill.

The doctor agreed to perform Ismails surgery after he described his lifestyle, which is regular exercise and healthy eating habits. LoMonaco said he does not operate on 20 percent of the people seeking skin removal because they havent found a stable program to maintain their rapid weight loss.

When he first started losing weight, Ismail knew how to pour a bowl of cereal and make scrambled eggs. He bought pre-packaged foods that were often full of preservatives.

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Now, he buys fruits, vegetables, dairy and a lot of lean protein. He drinks a fair amount of coffee and admits to a slight Coke Zero addiction.

I am less restrictive on my diet than I used to be, and I learned from my mistakes in the past, he said. I was so serious about losing weight that I gave myself no freedom. Now that I know I can eat healthy 95 percent of the day, I can have ice cream or a cookie.

A healthy lifestyle is a marathon, not a sprint. It took Ismail a while to understand that, though. The work is nowhere near done, he said.

Its just putting in the work, its like second nature now, he said. I can do anything as long as I put the hours into it. Mentally, its a weird feeling because after doing all this, everything is relaxed now. I dont worry about weight loss I dont have to think about it anymore.

julie.garcia@chron.com

Twitter.com/reporterjulie

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After losing 235 pounds, Houstonian commits to the marathon of healthy living - Houston Chronicle