Study: Citizens in Good Health, Living in Safer Neighborhoods More Likely To Vote – Times of San Diego

Share This Article:Weekend voting at the headquarters of the San Diego County Registrar of Voters in November 2016. Photo by Chris Stone

A study released Thursday shows that California residents in good health with little psychological distress and better access to health care are more likely to consistently vote.

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The percentage of adults who reported that they always voted was highest among those who said they were in excellent or very good health just under 41% and who had experienced no psychological distress in the past year just under 41%.

Thats compared with 37.4% who reported being in good health and 32.7% who reported being in fair or poor health, according to the brief released by by the UCLA Center for Health Policy Research.

On the other hand, just over 23% of those who reported experiencing psychological distress within the past year reported that they always voted.

Voter registration and participation were also lower among respondents who had worse access to health care, the authors reported.

The study found that just over 40% of those who had visited a doctor in the past year said that they always voted compared with 28% who had not seen a doctor during that period.

The disparities in voting may make it less likely that the needs of the less healthy and more disadvantaged in the state are being addressed, the researchers concluded.

We found differences in voting by health and neighborhood factors that suggest that people who vote are healthier, have better access to health care and live in more cohesive and safer neighborhoods than those who dont vote, said Susan Babey, the studys lead author and a senior research scientist at the center.

These differences in civic activities such as voting could contribute to policies that fail to meet the health needs of Californians who are less healthy, face barriers in access to health care and live in disadvantaged communities, which may in turn lead to greater inequities in health.

The study used data from the centers 2017 and 2018 California Health Interview Survey. The results also showed that:

Latinos, individuals in Generation X (ages 38 to 53), those with less than a high school education and those in the lowest income group, were most likely to report that not being eligible was the main reason they were not registered to vote, according to the study.

Many California adults offered reasons for not being registered, such as incorrectly believing they are not eligible to vote or not knowing how to register, that could be addressed with targeted voter engagement efforts, Babey said. Importantly, these reasons were more likely to be offered by groups that already experience health inequities, including low-income adults, those with limited English proficiency, Latinos and Asians.

Joelle Wolstein, a co-author of the study, said researchers recommended a combination of strategies to increase participation in voting and other activities. They include providing civics education and pre-registration opportunities in settings such as high schools and supporting integrated voter-engagement activities, including get-out-the-vote efforts.

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Study: Citizens in Good Health, Living in Safer Neighborhoods More Likely To Vote was last modified: September 17th, 2020 by Editor

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Study: Citizens in Good Health, Living in Safer Neighborhoods More Likely To Vote - Times of San Diego

Spotlight: An easy, tasty way to healthy living [Free read] – WYDaily

Dieting, watching what you eat, and learning new methods to stay fit can be hard to juggle if youre a beginner.

What if getting started was as easy as adding olive oil to your daily cooking? We caught up with owner of Emblem Olive Oil, Chasity Pritchett to learn more.

Chasity started her olive oil company after simply tasting a co-workers infused oil. She knew there was something special to using high quality, flavor-infused oils with her food. She learned as much as there is to know about the nutrients and health benefits and immediately got started on her journey with Emblem Olive Oil.

Not only does Chasity offer a familiar face behind the product (her face is literally on every bottle) but she also offers a personal training program to help people get the full health benefits of cooking with olive oil.

Her Lets Fight Back program is a 12-week coaching session full of Zoom meetings, recipes, shopping lists, and uplifting group support to help you achieve your health goals.

In her very first session the group was able to help one member lose 30 pounds and completely come off her insulin, and everyone ended the 12 weeks feeling lighter and healthier.

The best part, Chasity does this at no charge.

Why would someone offer a program like this at no charge? She hopes that her customers learn to love cooking with olive oil but really because of The joy of knowing that you are helping someone that has been so insecure for so long, been overweight for so long and now they have a chance to love themselves and others.

Its no wonder that her business is booming and shes even just been named a Top 40 Under 40 award recipient for 2020.

Visit EmblemOil.com to see a full list of amazing infused flavors to include Roasted Garlic, Spicy Cajun, and even Smokey Mesquite. You can also now find them in store at Virginia Gourmet, at Williamsburg Premium Outlets.

These amazing oils are made from olives grown in Texas. The business supports a Hampton Roads local, and most important to Chasity, these olive oils are made in America!

Check out one of the recipes that Chasity shares with her Lets Fight Back group and get cooking!

Chicken, Peaches and Emblem Olive Oil

Heat a large skillet over medium high heat. Season the chicken breast all over with sea salt and pepper. Add Emblem Extra Virgin Olive Oil to the skillet, when the oil shimmers, add the chicken breast and sear on both sides for 3-4 minutes. Reduce the heat to medium and continue cooking for about 8-10 minutes, or until the chicken breast are cooked through.

In a small bowl, whisk together more Emblem Extra Virgin Olive Oil, raw honey, and oregano.

During the last 2 minutes of cooking, pour the extra virgin olive oil sauce over the Chicken Breast. Remove from the heat and add the peaches. Transfer the skillet to the oven and broil for 4-5 minutes or until the peaches are lightly charred.

Remove from the oven and top with feta, fresh basil, and chili flakes. Serve the chicken with the peaches!

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Spotlight: An easy, tasty way to healthy living [Free read] - WYDaily

Designing with the grain: making healthy living easier – nesta

Many of our food choices are not conscious, deliberative decisions but instinctive responses to our environment.

Although we might feel that we freely choose the food we eat, our eating behaviour is heavily influenced by the availability and convenience of food, prompts in our environment, and the social and informational landscape around us. We are no match for our current food environment which pushes us towards buying and consuming unhealthy food that is affordable, easily accessible and readily available.

The result is a public health crisis: 63 per cent of English adults are overweight and 28 per cent are obese.[1] Excess weight increases our risk of high blood pressure, type 2 diabetes, heart disease, stroke and cancer.[2] Ultimately, this translates into higher mortality rates; diet and high body mass are the second and third highest risk factors for life lost, the first being tobacco.[3] However, this loss of healthy life is not evenly distributed among us. Obesity rates are 80 per cent higher in the UKs most deprived areas compared to the least deprived.[4, 5] This disparity begins early; a five-year-old in one of the UKs most deprived areas is more than twice as likely to be obese than their wealthiest peers.[6]

We must ensure that our environment the places we shop, the foods we buy, the streets we walk on makes healthy eating easier.

Fundamentally, obesity is on the rise because most of us consume more energy in the form of calories than we burn through physical activity. Food, of course, means more to us than just caloric energy, but this suggests two approaches to tackling obesity: reduce calorie intake or increase physical activity. Whilst physical activity should be promoted for a variety of health reasons, evidence suggests that reducing excess calories is the key to tackling obesity.[7] Indeed, Public Health England estimates that the average adult consumes 195 excess calories each day, the equivalent of just one 40g bag of crisps or a pint of beer. This increases to 320 excess calories for people who are overweight or obese.[8]

The consequences of obesity do not only impact the individual; in 201415, the NHS spent more than 6 billion tackling the direct consequences of obesity.[9] More recently, the COVID-19 pandemic has provided yet more evidence of the devastating consequences of excess weight. As Public Health England recently reported, obesity is the single greatest modifiable risk factor for COVID-19 hospitalisation, after nonmodifiable factors such as age.[10] All else equal, the relative risk of critical illness from COVID-19 more than doubles for patients living with excess weight or obesity.[11, 12]

To protect the nation against COVID-19, the government has recommitted to tackling obesity. Doing so effectively requires rethinking and rebuilding our food environments with human behaviour in mind.

For decades, the narrative around obesity assumed that people make a conscious choice to overeat and not exercise. However, the truth is that our food environments have an enormous influence on the choices available as well as the options we choose. We all tend to eat what is in front of us until it is gone. What is in front of us is often determined by our habits and routines, which are heavily influenced by our income, external cues, social settings and the environment around us.

We have all been in situations in which we intend to do something, but are pushed in the opposite direction. We may intend to cook dinner from scratch, but when tired returning home from work we pick up a takeaway at one of the many outlets on the way. Similarly, we may not plan to snack after school, but our friends want to meet up at a shop on the high street. Or, we may plan to buy fruit at the supermarket, but when we enter our local store the price of fresh produce is up, while our favourite biscuits are on promotion.

Our choices are heavily influenced by the environment around us, and our food environment has undergone a rapid transformation. It is now incredibly easy to access tasty, but calorie-dense, food from an array of outlets on our high streets. The number of fast food outlets has increased[13] and portion sizes are often larger than those sold by retailers.[14] This is particularly apparent in deprived areas, which have a higher density of fast-food outlets.[15] Unhealthy food is also widely advertised and promoted, nudging us towards buying and consuming excess calories.

The detrimental impact of our environment on our weight is exacerbated by our increasingly complex and busy lives. High cognitive strain, time pressure, financial worries and other stressors can lead to less healthy food choices[16], and impede efforts to be physically active.[17, 18] The basic principle is this: when we are under strain or have little time available, we are likely to find it particularly difficult to make health-conscious choices; we default to what is most attractive and easily available in the immediate environment.

In short, when it comes to food consumption, willpower, education and attitudes to eating are no match for obesogenic food environments.[19] As such, the physical, social and informational environment within which we find ourselves must ensure that the healthy option is the easy, default one.

To tackle obesity, we need to create a food environment that is designed with human behaviour in mind to make it easier to choose the healthy option.

In the past, weve seen environment-focused approaches used effectively to address health issues. Arguably, the most impactful change to public health policy was the 2007 ban on smoking in all enclosed workplaces, including bars and restaurants. This policy was built around an understanding of the nature of smoking behaviour that it is inherently habitual and often social. By making it inconvenient and anti-social to smoke ensuring our physical, social and commercial environment makes it harder to be unhealthy the ban achieved its aim with immediate effect; there was a 6.3 per cent drop in the volume of cigarettes sold in England in the 3 months after the ban was implemented[20] and rates of smoking have steadily declined since.[21] This policy approach did not create a backlash either. Since the smoking ban was implemented, there has been increasing support from the public for even stronger measures to reduce smoking.[22]

Our approach to tackling obesity in the UK must be similar.

Imagine a world in which the food available to us is reformulated to be healthier and keep us fuller for longer. A world in which healthy foods are available and accessible to everyone because they are cheaper and more abundant. A world in which we can all make better choices about the food we eat and where we shop based on easy-to-understand nutritional labelling and reliable information on which shops will support us in making healthy choices. A world in which we are not unfairly influenced by adverts, in-store promotions and attention-grabbing positioning of the unhealthiest food. A world in which the healthy option is the easier option for everyone.

Policies need to focus on environmental changes that support people in making healthier marginal choices, but also harness the power of market forces to push industry to develop and promote healthier versions of similar foods, ensuring the options available are universally healthier for everyone. For example, when faced with ice cream in a supermarket aisle, very few of us will turn back to the vegetable section and select carrots instead. However, some may be prompted to choose frozen yoghurt as a healthier alternative to ice cream. If enough consumers make this substitution, retailers will begin to stock more frozen yoghurt and less ice cream. Producers will shift production, looking for healthier varieties of dessert. Thus, more and better varieties of healthier options become widely available and the market changes.

Critically, built into this approach is a focus on reducing health inequalities. Constrained choice, education levels and the burden of financial strain all contribute to obesity-related health inequalities. Instead of urging individuals in disadvantaged areas, where obesity prevalence is greatest, to purchase healthier foods or exercise more, an environment-focused approach puts the onus on policymakers, retailers and producers to ensure our environments support our health.

Additionally, by focusing on shifting our food environment, we can tackle obesity without removing pleasure from food or amplifying disempowering narratives about body image, both of which have had little positive effect on reducing obesity and may have negative consequences on mental and physical health.

To tackle obesity we need a combination of innovation methods, unusual coalitions, experimentation and government leadership through policy. The measures set out below are examples of how an environmental-focused approach can be used to support healthier marginal choices and shift consumer demand. While the UK Governments new obesity strategy[23] acknowledges that the environment we live in plays a huge role in shaping what we eat, these are the kinds of bold changes that the government should consider to take the obesity strategy further.

There is a particularly strong case for focusing on product reformulation as it does not require us to change our eating behaviours or food cultures. We can eat the same products, consume the same amount and enjoy the same traditions, but with fewer calories. Evidence shows that consumers tend not to notice reformulation; eating fewer calories and yet feeling just as full. The Sugary Drinks Industry Levy or sugar tax, for example, took 28 per cent of sugar out of the UKs soft drinks market without impacting sales or satisfaction.[24] Portion size reduction also shows potential; evidence suggests that calorie intake would be reduced by around 14 per cent in UK adults if large food portions, packages and tableware were not available. [25]

Following the success of earlier salt and sugar reduction programmes, Public Health England has been working with food producers to reformulate and reduce the portion sizes of those food types which contribute to around 50 per cent of childrens daily calories.[26] However, there are significant technical challenges in solid food reformulation, and issues related to interfering with market competition.

For some high fat, salt and sugar foods there may still be a case for direct regulation, such as well-designed taxes or levies. Learning from the success of the Soft Drinks Industry Levy (SDIL) or sugar tax, the design of any tax should carefully select thresholds that industry can feasibly reformulate to meet. By encouraging reformulation, the benefits of reduced levels of fat, salt or sugar can be distributed equitably and not just enjoyed by the most health conscious among us.

Whilst there are obstacles for reformulation of some products, it may be possible to catalyse market innovations and diffusion through other means. For example, challenge prizes could be used to find new ways to produce food that is considered hard to reformulate with business-as-usual R&D alone.

Another approach would be to harness market forces to encourage reformulation. Offering attractive, cheaper and, crucially, healthier alternatives can nudge consumer demand. Like substituting frozen yoghurt for ice cream, if enough consumers choose the marginally healthy alternative, retailers will shift the items they stock and producers will shift production to cater for the healthier choices.

Collective intelligence, such as citizen-generated data [27] about which foods different cohorts of people would find acceptable to substitute, can be used alongside data on food purchasing and pricing to target foods that would most effectively drive producers to reposition or reformulate in ways that consumers wouldnt mind (or even notice).

It is this idea of using marginal shifts in consumer demand to drive changes in product formulation, size, price and positioning that is central to making it easier for everyone no matter our circumstances to live a healthy life, without taking the joy out of food.

Unhealthy food is widely advertised and promoted, nudging us towards buying and consuming excess calories. The governments new obesity strategy [28] outlines plans to implement a 9pm curfew, as well as consult on a possible total ban on online advertising of high fat, salt and sugar products. The case for restricting the advertising of unhealthy food is compelling. Even after accounting for potential losses to broadcasters, advertisers, manufacturers and retailers, the introduction of a 9pm curfew for junk food advertising is estimated to result in a net gain of 2 billion. The health benefits for the individual, cost savings for the NHS and social care, and increased economic output due to reduced premature mortality are estimated to outweigh the potential losses.[29] Moreover, we would not be constantly bombarded with unhealthy food advertisements.

The obesity strategy also confronts how food is marketed and promoted in stores, with plans to end promotion of high fat, salt, and sugar products by volume (such as buy one get one free deals) and location (such as prominent displays at shopping tills or end of aisles).

Regulating advertising further, beyond the curfew, could also help to drive product reformulation. By banning advertising and promotion of the most unhealthy foods, particularly those highest in fat, salt or sugar, and also instituting lighter restrictions on the next band of unhealthy foods, the government could drive progressive reformulation across these boundaries similar to the way in which the tax bands of the sugar tax drove reformulation of soft drinks.

In addition, relatively little is currently known about the impact of advertising online compared to traditional broadcasting. In order to help inform the proposed consultation of online advertising, it will be important to understand how many online ads different individuals see, and the relationship between ad types and lengths, increased purchasing, and eating behaviour. For example, we shouldnt assume that a five-second advert is only one-tenth as effective as a 50-second one, but without knowing more about the dose-response of online ads, the government cannot make informed, effective policy.

For in-store marketing and promotion, collective intelligence and behavioural insights can help inform further product positioning and promotions that drive consumer choice in this changing landscape of marketing. Experimental trials in real-world settings including in partnership with larger chains, small convenience shops and international food stores can help test changes and evaluate impact for diverse consumer groups. Additionally, there is potential to take regulations further by linking nutritional labelling to prominent positioning in-store. For example, banning any products that score red on nutritional labels from being at eye-level, particularly for children.

Policies targeting individual behaviour change need to be designed with an understanding of human behaviour, adopting a strategy of substitution, rather than expecting large step changes in behaviours. Even the relatively small reduction in calories in a marginal choice, if scaled to the majority of the population, will have a large impact.

An experimental study by the University of Cambridge reported that, when online shopping, one in four suggested swaps were accepted by consumers.[30] Small changes to the architecture of supermarket websites are likely to feel acceptable to consumers, supporting them in making healthier choices whilst maintaining clear autonomy. This seemingly innocuous approach offering a healthier alternative if taken to scale, would immediately take calories off our plates.

To support consumers in making marginally healthier choices, we need helpful and easy to understand nutritional information. In isolation, nutritional labels have only modest impacts on consumer behaviour, but front-of-pack heuristics, such as the colour-coded Nutriscore labels, have shown promise.[31, 32] The governments new obesity strategy acknowledges the importance of front of pack nutritional labelling, with plans to publish a public consultation on the current UK labelling.

A more ambitious step to support consumers in making healthier choices could be to go beyond individual products and to sharpen competitive pressure between retailers and food outlets. Most UK consumers have multiple choices of where to buy food and these retailers and out-of-home food outlets compete aggressively. Offering consumers more reliable information on which of their local retailers offer healthy products may tilt the balance of competitive pressure in favour of healthier options. Information provided could include to what extent retailers focus special offers on healthier foods, put healthy food in more prominent locations, and stock healthier products. Sharpening competitive pressure offers an under-utilised approach to shifting consumer demand, and warrants further exploration. Whats more, this information could also be used to set zoning and licensing thresholds, enabling local councils to ensure every neighbourhood has adequate access to healthy choices.

Healthy substitutions and effective information on how healthy our food and shops are will impact individual consumer choice, but they also drive a secondary form of impact; producers will be encouraged to reformulate their products to avoid substitutions or an unhealthy label, whilst retailers will make changes to receive a more competitive healthy rating. While initial demand might shift most amongst those who make a conscious decision to choose a healthier alternative, the resulting reformulation and changes to our food environment would have a positive effect on all consumers, thereby helping to address health inequalities.

While we must not lose this critical window to achieve change through policy, we also must not forget the lessons we have learned about why good, healthier alternatives often fail to scale, including, all too frequently, a lack of consideration for demand. So how do we know what alternatives would be desirable? And how do we ensure that alternatives still enable our plates to reflect our food cultures, traditions and desires?

One way of finding out might be to use food consumption to recommend smart substitutions. For example, supermarkets can use nutritional information on their products to figure out which foods might make good, healthy substitutes. By combining this nutritional analysis data with wide consultation about what people actually want and buy, it is likely these recommendations can be sharpened. For example, nutritional analysis alone might suggest that cottage cheese could sub-in for cream in many recipes but its very unlikely a person would accept this as a suggested swap. On the other hand, learning how diverse groups of healthy consumers swap might reveal alternatives that arent obvious from a nutritional profile alone.

By using data science and innovative consultation methods in partnership with shop owners, food producers, health experts and consumers, we can jointly identify alternatives we want to eat, stocked in the places we shop. In doing so, the change in consumer demand required to marginally shift our food choices is within reach.

Alongside this, we need to design an impactful front-of-pack nutritional label built on a realistic model of how consumers of all levels of education and food literacy, and with diverse cultural backgrounds will interact with information, rapidly and at a surface level. For example, we might consider simplifying labels by using summary or interpretive information, keeping a colour system to attract attention and aid interpretation, and ensuring a single labelling modality is used across products and settings (in addition to back-of-pack calorie and nutritional information).

To encourage healthier choices, labels that emphasise excessive unhealthy nutrient levels are more effective than those that promote the health benefits of alternative products, driving consumers away from unhealthy products.[33] The inclusion of additional nutritional measures, such as satiety the measure of how full you will feel after eating should also be considered.

Innovative methods and robust testing should also be used to explore the possibility of healthy eating ratings for stores and food outlets. First, collective intelligence tools can help us understand what factors influence the decision on where to shop, what information would be useful to consumers, and how this differs across the population. Designing a rating system that is easy-to-understand and helpful would be crucial, as would extensive and robust testing in real-world settings.

In developing new nutritional labels, the threshold at which nutrients are classified as red should be carefully considered in order to encourage the reformulation of products and avoid consumer-deterrent unhealthy labelling. Similarly, the characteristics of stores or food outlets that lead to a less healthy food environment rating should aim to encourage retailers to make reasonable changes to receive a more competitive healthy rating, and be accompanied with reasonable measures to support small and independent shops to adapt.

Selecting appropriate unhealthy criteria to drive change and designing labels and food environment ratings that are acceptable and impactful for consumers will require unconventional partnerships amongst government, industry, retail and consumers. Collective intelligence, behavioral insights, and experimental methods are crucial for ensuring that labels and ratings are designed for harm reduction and are effective in shifting consumer behaviour.

With the governments renewed focus on tackling obesity, now is the moment to be bold. Our food environment must be redesigned with human behaviour in mind whilst avoiding removing the pleasure from food or requiring constant attention to food choices.

Instead, we need an environment-focused approach that will encourage retailers, producers and consumers to produce and demand fewer calories. Innovative methods, including behavioural science, data science, innovative financing and collective intelligence offer powerful tools to inform policies that both support people in making healthier marginal choices and also harness the power of market forces to push industry to develop and promote healthier versions of similar foods.

Importantly, by minimising the associated time, effort and costs of making healthier choices, an environment-focused approach can reduce the constraints that low income places on healthy eating, reversing the rising trend in obesity levels without widening health inequalities. In other words, supporting everyone to live well.

During the COVID-19 pandemic, we have all shown extraordinary willingness to accept changes to our environment as part of the effort to protect public health. Now is the time to be bold and tackle our food environment, changing the architecture of our daily lives to go with the grain of human nature, making it easier to live healthy lives.

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Designing with the grain: making healthy living easier - nesta

Here’s To Your Health | Living – Elk Valley Times

Registered Dietitian South Central Human Resource Agency Head Start

Scientists from the University of Illinois and Ohio State University have been tracing how tomato compounds help reduce the risk of prostate cancer in humans. Many men between 40 and 50 years of age develop early-stage prostate cancer, and it may continue to develop over 20 years. Its important to reduce the growth of the tumor. If one can control this by diet, many lives could possibly be save.

Tomatoes contain a symphony of nutrients that may be responsible for their cancer-protective properties, including Vitamins A and C, fiber, and carotenoids, which give tomatoes their red, yellow, and orange colors. The most abundant carotenoid is lycopene, which has been linked with cancer protection. Tomatoes account for 80 per cent of lycopene in the American diet. Today about 75 per cent of the total U.S. tomato crop is processed into juice, canned tomatoes, sauces, paste and ketchup.

While earlier research has focused on prostate cancer prevention, newer studies are looking at early treatment and slowing the disease progression. Tomato products look very promising, according to John Erdman, PhD, professor emeritus of food science and human nutrition at the University of Illinois whos been studying the effects of tomatoes on prostate cancer since the mid 1990s.

Erdman believes the cancer protection seen in tomatoes isnt a mere result of lycopene. More effective benefits have been linked with the whole tomato, which contains a full range of carotenoids and nutrients. Research shows that single daily servings of processed tomato products produce significant increases of lycopene concentrations in the blood of healthy adults. Evidence indicates that the lycopene from processed tomatoes is more bioavailable than that of fresh tomatoes. The heat from processing breaks down the tomato cell walls and , therefore, increases the absorption of lycopene in the body.

An analysis including 11 case-control studies and 10 cohort studies indicated that those eating raw tomatoes regularly had an 11 per cent reduced rate of prostate cancer than nonfrequent users . of tomato products. Those with a high intake of cooked tomato products experienced a 19 per cent lower risk then those who rarely used tomato products. Using a lycopene supplement doesnt seem to improve disease status, as measured by PSA (prostate-specific antigen) levels.

While we have much more to learn about how tomatoes fight prostate cancer, most experts agree ( including the American Institute for Cancer Research) its a good idea to eat more tomatoes as part of an overall strategy to increase fruit and vegetable intake. This should be part of an overall health-promoting strategy that includes regular physical activity, maintaining a healthy weight, eating a diet with an abundance of plant foods, and limiting red meats. Eating 2 or 3 servings a week of tomatoes and tomato products appears to be a sufficient amount to possibly lower risk of prostate cancer.

Try this tomato-rich recipe! The recipe makes 3 large or 6 small servings. Each small serving contains 75 calories and 2 grams of protein.

Wash 3 medium-sized fresh tomatoes. Remove hard part of stem end. Cut into halves crosswise. Place in oiled baking dish, cut side up. Sprinkle with salt and pepper and grated cheese. Cover with buttered bread crumbs. Bake at 350 degrees Fahrenheit until tender,

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Here's To Your Health | Living - Elk Valley Times

Healthy Aging Month observed nationwide in September – News – The Hutchinson News

September is Healthy Aging Month, an annual observance that deserves more attention this year as the nation deals with a pandemic unlike anything we have experienced for a century. Medical Author Dr. William W. Shiel, Jr. defines aging as the process of becoming older. Aging is not the same for any two people, due to factors including lifestyle, environment and family genetics. According to medical experts, the first signs of aging appears on the surface of the skin during the mid-20s.

More than 80,000 Americans are over the age of 100 and 20,000 have surpassed their 105th birthday, two statistics that continue to grow. Many remain active and live independently. Both major party candidates for president this year are more than 70 years of age.

Aging has been called the greatest known risk factor for most human diseases and can be either physical or psychological. Approximately 150,000 people die daily worldwide, two thirds of which are from age-related issues. Older adults and those who have underlying health conditions such as heart and lung issues and diabetes are at increased risk of severe illness, including COVID-19. Adults 65 years of age and older account for 16 percent of the nations population, but 80 percent of COVID-19 deaths claim this group of people.

The pandemic has resulted in increased stress in the lives of all Americans, and, in particular, those who are older or confined to home.

The effects of stress include:

Needless fear and worry about ones healthChanges in sleep or eating patternsDifficulty concentratingWorsening of chronic health problemsWorsening of mental health conditionsIncreased use of tobacco and/or alcohol

Stories regarding accomplishments of older Americans are more frequent these days and serve as encouragement for all. In 2014, 90-year-old Ernie Andrus walked, or as he said, "jogged" across America to honor the ship he served on during World War I. That same year, former President George H.W. Bush, to celebrate his 90th birthday, parachuted out of an airplane, smiling all the way to the ground, as his frightened family watched nearby.

Locally, Judge Wesley Brown, appointed a federal judge in 1962, served one-year shy of a half-century before passing away in 2011 at the age of 104. In an Associated Press interview on the year of his death, Judge Brown was asked to explain his longevity as a member of the federal judiciary, and his response was brief, to the point, and similar to his traditional courtroom demeanor. "As a federal judge, I was appointed for life or good behavior, whichever I lose first," Brown said. In a follow-up question, the reporter asked how he planned to exit the job, he said, "Feet first."

So, what advice can a healthcare professional possibly give to hearty souls to ensure they will continue healthy living, particularly in these unprecedented times? Keep masks, tissues, and hand sanitizer in your possession when venturing out. If possible, avoid others who are not wearing masks. Ask others around you to wear masks. Make certain your vaccinations and other preventive services are current, stay physically active and practice healthy habits to cope with stress. People of all ages who adhere to these precautionary measures will hasten the day when COVID-19 will be an event of the past. That day could not come any too soon.

Ken Johnson is President and CEO of Hutchinson Regional Healthcare System.

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Healthy Aging Month observed nationwide in September - News - The Hutchinson News

Healthy Living: A new routine to lose the Covid stone – Leinster Leader

So, at long last the children are gone back to school. Long may it last! I think nearly every parent in the country swore that everything was going to change when the kids went back to school. Back to healthy eating, getting in the 5km walk a day and drinking gallons of water, all in the hope of losing the covid stone.

In reality it may have been a case of, peace at last so time to break out the choccie biscuits. Before you know it, you wake up and its Tuesday and you cant start a diet on a Tuesday.

So, you may overindulge over the next few days with the mindset of starting again next Monday, and this pattern goes on week after week.

Does this sound all too familiar? As a busy mum of five, I totally get this and Im here to help you with my tips and ideas to keep you reach your goals for a happy and healthy you.

1. START WITH A PLAN

One of the best things you can do for yourself is to get into the habit of planning your family meals. This will save you time and money. Planning meals in advance ensures you use up the ingredients you have before buying more. Get the whole family involved by allowing everyone pick a meal. There is a meal planner in my 28-day rescue plan, download it free from my website and get writing!

2. WRITE A LIST

Write a shopping list for the ingredients you need to put your meal plan into action. This will save you time wandering around the shop wondering what to buy and save you money as you will be less likely to put unwanted items in your trolley. And of course, none of us want to be hanging around the supermarket longer than we need to.

3. PLAN FOR LEFTOVERS

Plan for leftovers to be used the next day as lunch. For example leftover chili is delicious the next day when heated in a wholemeal pitta bread or wrap with grated cheese, avocado and salad. Leftover roast chicken is so versatile and can be used in salads or wraps. My personal favorite is to make an egg fried rice with it.

4. PREPARE FOOD IN BATCHES

If your family are great at coming up with the meal plan ideas but not so great at helping to prep or cook it, then lighten your load by prepping once to eat multiple times.

Chop and wash a variety of veg all at once, then place them in an airtight container in the fridge to use as snacks. Carrots, celery, peppers all make great snacks to dip in hummus or cream cheese.

Double your recipe ingredients and store them in the fridge or freezer and you will have a meal ready to be cooked when you want it. This works great for curries. Just pop your chicken and veg that has been marinating in the lovely spices into a pot with a tin of coconut milk, simmer for 20 minutes and you have a tasty meal on the table that the whole family will love. Check out my curry recipe on my website http://www.thenutricoach.ie

5. ENSURE YOU ARE GETTING A WIDE RANGE OF NUTRIENTS

Its important to remember there is no specific food or supplement that will help you lose weight or boost your immune system, contrary to what you see on social media. However, a healthy balanced diet thats low in sugar and processed food and high in nutrients that support the immune system such as, vitamin c (berries, tomatoes, peppers, citrus fruit) vitamin A (sweet potato, spinach) vitamin D (oily fish, mushrooms) zinc (meat, shellfish, dairy) is the best thing you can do for your immune system and your waistline.

6. EAT REGULARLY

As tempting as it may be to restrict your calorie intake, skipping meals is never a good idea. Going long periods without eating causes your blood sugar to drop, which leads to fatigue and cravings for sugary snacks and stimulants. Aim for three main meals a day and include a maximum of two nutritious snacks, such as a piece of fruit with four or five nuts, vegetable crudits with hummus or sliced apple dipped in nut butter or try out my no bake energy balls!

7. EAT A SOURCE OF PROTEIN WITH EVERY MEAL OR SNACK

When you eat carbohydrates alone, they quickly get digested and converted into sugar which is then absorbed into your blood stream causing a spike in blood sugar. However including a source of protein with your meal or snack slows down digestion. This leads to a slower absorption of carbohydrates, therefore a lower rise in blood sugar, so less of the fat storing hormone insulin is needed, and protein will help you feel full for longer resulting in less snacking.

8. STAY HYDRATED

Drinking water has many benefits, including boosting your metabolism and suppressing your appetite. When you dont drink enough water, your body receives mixed signals from the hypothalamus, which is the part of the brain that regulates appetite and thirst. A lot of the time when we think we are hungry, we are actually dehydrated. Aim to drink two litres of water a day. This can be achieved by starting your day with hot water and lemon, adding lemon slices, cucumber and mint leaves to a jug of water and sipping throughout the day and having some herbal teas.

9. FOLLOW THE HEALTHY PLATE GUIDE

The healthy plate guide is an easy way to make sure you are having a well-balanced meal, just fill half your plate with vegetables, a quarter of your plate protein/healthy fats e.g. chicken, meat, fish, eggs, lentils, and a quarter of your plate low GL carbohydrates e.g. sweet potato, brown pasta or rice, quinoa.

Are you struggling to get back to healthy eating and getting your weight back to what it was pre-Covid? why not schedule in an appointment with The Nutri Coach! There is no time like the present My clinic open and I am taking bookings for new and existing clients, so just pop me a message if you would like to schedule an appointment. contact details below.

Debbie Devane from The Nutri Coach is a qualified Nutritional Therapist and health & lifestyle coach, Debbie runs her clinic from the Glenard Clinic in Mountmellick and also offers one to one and group online consultations. Debbie is also Nutritionist to the Offaly GAA senior footballers.

For more information or to make an appointment email Debbie at

info@thenutricoach.ie

Ph: 086-1720055

Facebook: The Nutri Coach @debbiedevanethenutricoach

Instagram: the_nutricoach

For more information or to download your copy of Debbie's 28 day rescue plan go to http://www.thenutricoach.ie

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Healthy Living: A new routine to lose the Covid stone - Leinster Leader

Obese people 70% more at risk of severe COVID-19: Assocham – The Indian Express

By: Lifestyle Desk | New Delhi | September 18, 2020 8:50:25 pmKeep your weight in check to improve your body's vulnerability to Covid-19. (Source: Getty Images/Thinkstock)

An expert panel of nutritionists recently noted that obesity needs to be taken seriously and managed on priority basis in the wake of the sedentary lifestyles people have started following owing to the COVID-19 pandemic, with a focus on right food and exercise. Ishi Khosla, clinical nutritionist, Centre For Dietary Counselling stated that obese people have 70 per cent higher chances of contracting viral diseases and suffering from severe symptoms. She also elaborated on lifestyle diseases that are being triggered by COVID-19 like insomnia, adverse eating habits caused due to ungainly work hours and excessive screen time.

Speaking on the importance of consuming magnesium for people with insomnia, Khosla said, People who are generally healthy are complaining of not being able to sleep due to anxiety and the fear of uncertainty. There are two parts to tackling it, one is diet and the other is lifestyle interventions. Eat foods that is easy to digest. When your digestion is good, your body begins to relax and can focus on other functions. To calm your nervous system, specific vitamins and minerals, like magnesium can help people with anxiety and sleep disorders. It can also help in controlling cholesterol, diabetes and sleep management.

The discussion part of the sixth edition of the Illness to Wellness series themed Lifestyle Behaviour During COVID-19 organised by The Associated Chambers of Commerce and Industry of India (ASSOCHAM), one of the apex trade associations of India.

ALSO READ |From Ayurvedic kadhas to herbal meals: Immunity boosters are now serious business

Highlighting how diabetes is no longer just a cosmetic issue, Ritika Samaddar RD, regional head, Department of Clinical Nutrition and Dietetics, Max Super Speciality Hospital said: We have noticed that people who are obese, are the ones who are getting severe COVID-19. The mortality rate is high in such people. It is very important to understand that no longer can obesity be restricted to a cosmetic problem, but also as a medical issue. If you are healthy, your immunity is high so your incidence of any kind of infection would be much less. The public should consider obesity as a disease and take all precautions like dietary, lifestyle or medical management to control it, she said.

Equating healthy living to better immunity, Samaddar shed light on the need to exercise regularly. She added that people need to get back to physical activities like walking, jogging, cycling and running even if gyms continue to remain shut as this is going to be the new normal.

ALSO READ |Lockdown diet: Feel sluggish and have digestive troubles? Avoid these foods

Sharing a few quick tips on breaking the sedentary nature of working at home, Khosla emphasised the need to balance screen time and chair time. We need to keep moving so there should not be more than an hour of constant sitting. This should be followed by 10-15 minutes of walking or strolling. We need to take that break to get up and stretch. Sitting can lead to inflammation. Same goes for screen times. There has to be a pause button. She added that to battle obesity, focus should be laid on the consumption of functional and fermented foods. For non-vegetarians, she suggested, balancing meat consumption with an anti-inflammatory diet to keep the digestive and gut systems healthy.

For more lifestyle news, follow us: Twitter:lifestyle_ie|Facebook:IE Lifestyle| Instagram:ie_lifestyle

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Obese people 70% more at risk of severe COVID-19: Assocham - The Indian Express

HPB partners Apple to promote healthy lifestyle; S’pore residents can earn rewards of up to $380 for using app – The Straits Times

SINGAPORE - Your Apple Watch could soon beep to remind you when it is time for your health screening or immunisation, thanks to a new app developed by the Health Promotion Board (HPB).

Called LumiHealth, the free app, to be launched in late October, will also help users set fitness goals and healthy eating targets after drawing behavioural insights from the users' sleeping, health and fitness activities.

It is part of Singapore's national drive to promote a healthy lifestyle through the use of technology.

Developed by Apple and public health experts at HPB, LumiHealth is tailored to Singapore users in terms of health issues that are important to the population here, according to HPB.

Personalised nudges and reminders about physical activity levels or diet can, for instance, help prevent or delay the onset of illnesses and chronic diseases such as diabetes or to better manage these diseases.

Deputy Prime Minister Heng Swee Keat said in a statement on Tuesday (Sept 15): "Even as all of us around the world are dealing with the challenges of Covid-19, we must keep investing in our future. And there is no better investment than in our personal health.

"This partnership between Singapore and Apple will enable Singaporeans to lead healthier lives."

Apple's chief operating officer, Mr Jeff Williams, said: "Singapore has one of the world's leading healthcare systems and we are thrilled to be partnering with them to incorporate Apple Watch and LumiHealth into their holistic approach to well-being."

Fitness goals are gamified in the app, with a friendly character guiding users through different worlds and tasks, personalised according to age, gender and weight. These tasks include weekly activity goals that can be met by walking andswimming, as well asyoga and other activities.

Users can also take part in wellness challenges that aim to improve sleep habits as well as encourage better food choices.

For the two-year span of HPB's LumiHealth programme, users who complete these tasks and challenges will be able to earn rewards worth up to $380 in HPB eVouchers from stores like FairPrice, Sheng Siong and Tangs.

The app also reminds users to go for health screenings and relevant immunisations based on their demographic profile details such as age and gender.

LumiHealth is open only to Singapore residents aged 17 years or older with a SingPass account. It requires an iPhone running iOS 13 or later, and an Apple Watch with at least watchOS 6.

Data and health insights gathered by LumiHealth will help shape future health initiatives for improving the quality of lives of Singaporeans. However, the sharing of health data is dependant on the user's consent.

The collection of personal identifiable data is minimised and used only to administer the programme, for example, using e-mail addresses to ensure that the correct incentives are awarded to the right participants.

The data will be coded, secured and stored in Singapore.

Asked why the app is available only on Apple Watches, HPB said its long-term goal is to work with various device and technology partners "to increasingly leverage technology for our programmes".

"This will create an ecosystem of technology-enabled health promotion programmes that can target different segments of the population," the agency said.

While LumiHealth is designed specifically for Apple Watches, HPB said those who have other wearable devices can take part in other healthy living programmes such as the National Steps Challenge.

LumiHealth will complement other HPB population-wide programmes, such as the Healthy 365 app (available on both Android and iOS), to reach as many Singaporeans as possible.

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HPB partners Apple to promote healthy lifestyle; S'pore residents can earn rewards of up to $380 for using app - The Straits Times

Increasing Adoption of yy product to Drive the Anti-Aging Medicine Market – Lake Shore Gazette

Longer life-expectancy is a cumulative effect of a healthy lifestyle and favorable environmental conditions. A trend of continuously increasing life expectancy has been a witness since a decade, primarily because of advances in medical sciences and treatment of chronic life-threatening diseases, availability of clean water and environment and other factors. This trend is projected to further show even more exponential growth graph owing to the anti-aging medicines, stem cell therapeutics, genetic screening and interventions, and high-tech biomedicines. American Academy of Anti-Aging Medicine claimed that anti-aging medicines can add up to 10-20 years to the life expectancy of a human. Today, a combination of calorie-restricted diet, regular exercise, and anti-aging medicines are claimed to slow the process of senescence and aging. Various medicines used against the treatment of acute or chronic diseases can be considered as anti-aging medicines, however, to define anti-aging medicine market we have considered only the drugs that are directly prescribed and used for delaying the effects of aging.

The constantly growing demand to look young in old individuals and to remain young and youthful in young people drive the anti-aging market. The influence of aesthetics from the fashion and television industry propel the demand to retain the features and energy of younger age in old people. Additionally, the increasing number of anti-aging medicine manufacturers in the decade contribute to higher availability of the anti-aging medicine resulting in expansion of the global anti-aging medicine market. However, skeptical approach to anti-aging medicine as being an external stimulator of cell-cycles is a restraint to the expansion of anti-aging medicine market.

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The global Anti-aging medicine market is segmented on basis of product type, age group, distribution channel, and region:

The rising demand for beauty consciousness amongst people and the desire to stay young is the primary factor fueling the growth of anti-aging medicines in the market. The acclaimed benefits of the products and affordability along with regional presence compel the demand for anti-aging medicine in the global market. Hormonal replacement therapy segment in product type is expected to account maximum market share in the terms of revenue in the global anti-aging medicine market. However, antioxidant therapy segment in product type is expected to grow with the highest CAGR over the forecast years owing to the rising awareness about the plethora of benefits of antioxidants in anti-aging among the public. On the basis of the route of administration, the global anti-aging medicine market is segmented as oral, injectable and topical, out of which oral segment is expected to generate maximum revenue share over the forecast period. As per the distribution channel, the global anti-aging medicine market is segmented as hospital pharmacies, retail pharmacies, e-commerce, and drug stores. The e-commerce segment in the distribution channel is estimated to grow with the highest CAGR over the forecast time.

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Regionally, the global anti-aging medicine market is segmented into five key regions viz. North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America anti-aging medicine market is projected to account for the largest market share in the terms of revenue in the global anti-aging medicine market owing to the higher healthcare expenditure and presence of numerous manufacturers. Europe is expected to hold the second largest share in the global anti-aging medicine market during the forecast period because of the growing geriatric population and higher spending on healthcare products and supplements. MEA anti-aging medicine market is expected to witness sluggish growth over the forecast time owing to the limited presence of manufacturers and lower healthcare expenditure. Asia Pacific is projected to grow with the highest CAGR over the forecast years in the global anti-aging medicine market due to higher demand from end users and regional penetration of the key players in the region.

Some of the players operating in the global anti-aging medicine market are Pfizer, Evolution GmbH, Himalaya Global Holdings Ltd., Cipla Limited, Mylan Laboratories, Novartis, Merck Group, Vitabiotics, William Ransom & Son Holdings Plc, Uni-Vite Healthcare and Health Made Easy Limited amongst others.

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Increasing Adoption of yy product to Drive the Anti-Aging Medicine Market - Lake Shore Gazette

CollPlant Biotechnologies Presents on the Use of Novel, Plant-Derived, Recombinant Human Collagen for Anti-Aging Therapies at the Science of Aging…

REHOVOT, Israel, Sept. 16, 2020 /PRNewswire/ --CollPlant (NASDAQ: CLGN) a regenerative and aesthetic medicine company, today announced that Dr. Nadav Orr, Vice President of R&D, presented a corporate overview on the dynamics of cellular aging during Session 3 of the Science of Aging Virtual Symposium 2020. The presentation was titled, "Use of Novel, Plant-Derived, Recombinant Human Collagen for Anti-Aging Therapies."

"We are proud to showcase our plant-derived, recombinant human collagen or rhCollagen platform technology at the exclusive Science of Aging Virtual Symposium 2020 alongside other innovative companies in the aesthetic medicine space," says Dr. Nadav Orr, Vice President of R&D, CollPlant. "Additionally, September is Healthy Aging Month, which presents the ultimate opportunity for us as a company to illuminate our revolutionary Skin Rejuvenation and Breast Implant product pipeline inclusive of our photocurable dermal fillers."

Data presented at the symposium demonstrated smooth injectability and a statistically significant enhancement in proliferation of normal human dermal fibroblasts (nHDF) for cells treated with a combination of hyaluronic acid and rhCollagen relative to HA only following an 8-day treatment period.

About CollPlant

CollPlant is a regenerative and aesthetic medicine company focused on 3D bioprinting of tissues and organs, and medical aesthetics. Our products are based on our rhCollagen (recombinant human collagen) that is produced with CollPlant's proprietary plant based genetic engineering technology.

Our products address indications for the diverse fields of tissue repair, aesthetics and organ manufacturing, and, we believe, are ushering in a new era in regenerative and aesthetic medicine.

Our flagship rhCollagen BioInk product line is ideal for 3D bioprinting of tissues and organs. In October 2018, we entered into a licensing agreement with United Therapeutics, whereby United Therapeutics is using CollPlant's BioInks in the manufacture of 3D bioprinted lungs for transplant in humans.

In January 2020, we also entered into a Joint Development Agreement with 3D Systems Corporation, or 3D Systems, pursuant to which we and 3D Systems jointly develop tissue and scaffold bioprinting processes for third party collaborators. Our industry collaboration also includes the Advanced Regenerative Manufacturing Institute, or ARMI.

For more information about CollPlant, visithttp://www.collplant.com.

Safe Harbor Statements

This press release may include forward-looking statements. Forward-looking statements may include, but are not limited to, statements relating to CollPlant's objectives plans and strategies, as well as statements, other than historical facts, that address activities, events or developments that CollPlant intends, expects, projects, believes or anticipates will or may occur in the future. These statements are often characterized by terminology such as "believes," "hopes," "may," "anticipates," "should," "intends," "plans," "will," "expects," "estimates," "projects," "positioned," "strategy" and similar expressions and are based on assumptions and assessments made in light of management's experience and perception of historical trends, current conditions, expected future developments and other factors believed to be appropriate. Forward-looking statements are not guarantees of future performance and are subject to risks and uncertainties that could cause actual results to differ materially from those expressed or implied in such statements.Many factors could cause CollPlant's actual activities or results to differ materially from the activities and results anticipated in forward-looking statements, including, but not limited to, the following: the Company's history of significant losses, its ability to continue as a going concern, and its need to raise additional capital and its inability to obtain additional capital on acceptable terms, or at all; the outbreak of coronavirus; the Company's expectations regarding the timing and cost of commencing clinical trials with respect to tissues and organs which are based on its rhCollagen based BioInk and products for medical aesthetics; the Company's ability to obtain favorable pre-clinical and clinical trial results; regulatory action with respect to rhCollagen based BioInk and medical aesthetics products including but not limited to acceptance of an application for marketing authorization review and approval of such application, and, if approved, the scope of the approved indication and labeling; commercial success and market acceptance of the Company's rhCollagen based products in 3D Bioprinting and medical aesthetics; the Company's ability to establish sales and marketing capabilities or enter into agreements with third parties and its reliance on third party distributors and resellers; the Company's ability to establish and maintain strategic partnerships and other corporate collaborations; the Company's reliance on third parties to conduct some or all aspects of its product manufacturing; the scope of protection the Company is able to establish and maintain for intellectual property rights and the Company's ability to operate its business without infringing the intellectual property rights of others; the overall global economic environment; the impact of competition and new technologies; general market, political, and economic conditions in the countries in which the Company operates; projected capital expenditures and liquidity; changes in the Company's strategy; and litigation and regulatory proceedings. More detailed information about the risks and uncertainties affecting CollPlant is contained under the heading "Risk Factors" included in CollPlant's most recent annual report on Form 20-F filed with the SEC, and in other filings that CollPlant has made and may make with the SEC in the future. The forward-looking statements contained in this press release are made as of the date of this press release and reflect CollPlant's current views with respect to future events, and CollPlant does not undertake and specifically disclaims any obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Contact atCollPlant:

Eran Rotem Deputy CEO & CFO Tel: +972-73-2325600 Email: [emailprotected]

Sophia Ononye-Onyia, PhD MPH MBA Founder & CEO, The Sophia Consulting Firm Tel: +1-347-851-8641 Email: [emailprotected]

SOURCE CollPlant

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CollPlant Biotechnologies Presents on the Use of Novel, Plant-Derived, Recombinant Human Collagen for Anti-Aging Therapies at the Science of Aging...

Best Cities in the USA for Vegans Revealed – VEGWORLD Magazine

2020 Diet Destinations report reveals the best and worst places to live on a plant-based diet across the USA

Research shows more consumers are adopting vegetarian and vegan diets in the United States with younger generations taking on veganism at nearly double the rate of older Americans. The consumer spending experts at money.co.uk have produced a new report, which identifies the best locations for those eating a vegan, vegetarian, gluten-free and omnivore diet across the USA and Europe.

The study analyses the dietary and lifestyle offering for each location per diet:

Recent findings by Statista show that during 2019, 30.52% of the US citizens ate out a few times per month and more than 24% several times a week. The new data from the Diet Destinations study shows that Los Angeles, Houston and Phoenix are meeting demand with the highest numbers of speciality restaurants and takeaways in the country.

Vegans in L.A can choose from 1,036 plant-based restaurants and 1,596 takeaway services.

In comparison, there are 54% fewer vegan-friendly takeouts in New York, where locals can order from 911 spots, and 69% less in San Diego with 773 specialist takeaways in the city.

Top 10 best cities in the US to live on a plant-based diet:

Houston is named the best overall city followed by Denver, Los Angeles and Dallas.

Dallas is one of the most affordable places to buy groceries for a plant-based meal tomatoes, onions, lettuce and rice costs $6.42 which is 58% cheaper than for shoppers in New York here the same costs $11.79.

Despite being famous for barbequed meat dishes and chilli, Texas is the only state with two cities listed in the top 10 list. The state ranked highly for the number of speciality cooking classes and the cost of food.

The money.co.uk study revealed that Houston residents spend 59% less than city dwellers in Los Angeles to eat at home.

Based on 10 minutes cooking time, it costs 40% less in Houston to cook a homemade Vegan Risotto Salad three times a week. Yearly energy costs for cooking in the city are $1,051.20 , which is $525.60 less than in California, here residents are faced with annual costs of $1,576.80.

New York, Chicago and LA are the best places for those who enjoy socialising whilst learning invaluable cooking skills There are 3 times more specialist vegan cooking classes than in London, the overall highest ranking city.

The countrys green metropolitan city Seattle, is listed in the 10 worst places for vegans, along with southern states and California. The cost of food in the city is third highest in the country and it has some of the lowest numbers of vegan speciality restaurants.

Worst 10 cities in the US to live on a plant-based diet:

Ben Gallizzi, energy expert at money.co.uk, said: Whether you are vegan, veggie or gluten free, our new comparison tool will reveal the best destinations for your diet. As new eating habits emerge, its interesting to see which cities have evolved their grocery, restaurant and takeaway offering to suit the dietary requirements of its residents.

Cooking meals at home can soon rack up costs if you are not on the best energy deal. Our data reveals that some cities in the USA are paying almost double for their energy consumption its almost enough to put you off your dinner!

Foodies eating a vegan, vegetarian, gluten-free or omnivore diet can compare energy costs, number of restaurants and takeaways, speciality cooking classes and cost of food in their city in seconds with the new diet and energy comparison tool.

The full money.co.uk Diet Destinations report can be found here:

https://www.money.co.uk/guides/best-cities-for-your-diet

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Best Cities in the USA for Vegans Revealed - VEGWORLD Magazine

An Ad Promoting Veganism Aired During the Survivor Israel Finale – LIVEKINDLY

An Israeli ad about veganism is estimated to have reached one-third of the population. The ad aired during the season finale of Survivor Israel on Sunday night. The show is one of the most-watched series in the nations television history.

The commercial features a couple on a grocery run; when the man picks out frozen lamb, his partner stops him and says she wants it extra fresh.

The couple goes to the butcher counter to request fresh meat, where the clerk gives them a live lamb. The butcher asks: Would you like it chopped or wrapped?

The voiceover says: Youre not really surprised. More than a million Israelis have made the connection and stopped eating animals.

The commercial then directs viewers to google make the connection for information on how to start a vegan diet.

The Israeli audience saw on prime time, at the climactic moment of a reality show, the real source of the food it needs, Omri Paz, founder and CEO of Vegan Friendly, said in a statement. He added that the advertisement aims to bring veganism to the wider public discourse, and even influence many people to make a different choice when they approach the supermarket.

Paz estimates that 35 percent of the population saw the commercial.

Commercials promoting veganism that reach mainstream audiences are rare, but they exist. Late last year, Tesco, the UKs largest supermarket chain, aired a commercial promoting plant-based sausage that landed criticism from farmers. The 30-second advertisement depicted a young girl coming home from school. She then tells her father that she doesnt want to eat animals anymore.

So, he makes a meal using the supermarkets private label plant-based range instead.

Minette Batters, president of the National Farmers Union, claimed that the commercial demonizes meat. But, its more likely that it depicts an increasingly common household dynamic; sales of meatless food are expected to reach 1.1 billion this year, according to a Mintel report, driven by the nations flexitarians.

The commercial by Vegan Friendly is reportedly the first pro-vegan commercial to air in Israel, where interest in the lifestyle is on the rise. According to Google Analytics data compiled by Chefs Pencil, which shares recipes and industry trends, shows that Israel is one of the top three nations searching for information on veganism.

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An Ad Promoting Veganism Aired During the Survivor Israel Finale - LIVEKINDLY

Survey Reveals Top Countries & Cities in the World for Veganism in Our Post COVID World – vegconomist – the vegan business magazine

cienpiesnf-stock.adobe.com

Chefs Pencil has once again compiled data from Google Trends regarding the popularity of veganism in different countries and cities in the world, stating that interest is at an all-time high, surpassing the prior all-time high registered in 2019 and that veganism is now twice as popular as it was just five years ago.

It is highly interesting to see how the markets have changed since the impact of COVID around the world and how it has influenced consumers to increase their plantbased foods and decrease their meat intake. Click here to read previous findings by Chefs Pencil and compare them to 2020.

Also what is interesting to note is that the Google Trends analysis included all search categories related to veganism, to include all related searches in all global languages. As well as revealing the updated list of best vegan countries, Chefs Pencil also analysed the best cities in the world in terms of popularity scores based on Google searches. The top five cities in the world were shown to be:

1 Bristol, 2 Portland, 3 Edinburgh, 4 London, and 5 Amsterdam.

Read the rest here.

1. United Kingdom

Home of some of our most loved brands including The Vurger, One Planet Pizza, Meatless Farm, and countless others. It was shown that during lockdown this spring, vegan alternatives became increasingly popular in the UK, with one in 5 UK consumers reducing meat consumption, and a statistic from Finder showing that 39% of Britons plan to further reduce their meat consumption after the crisis.

In June, it was revealed by Mintel that aquarter of British millennials reported that COVID-19 made a vegan diet more appealing.

2. Australia

The third fastest growing plantbased market, home to emerging brands such as Fenn Foods producer of a plantbased carbon neutral mince, Fable, and Made With Plants to name a few. Convenience store chain 7-11 even sells a range of vegan sandwiches in Australia.

3. Israel

Most definitely the biotech home for many of the foodtech brands creating the future of our food system. Remilk is rethinking the concept of milk; SavorEat is creating a new generation of meat, and Yemoja is producing algae on a large scale in order to address the need for sustainable proteins. Enter Israel into our search bar to see many more.

4. Austria

An emerging market which was not on the previous top ten. According to the report, 1.2% of the population live a vegan life in Austria.

5. New Zealand

This meat-loving country is also a nature-loving nation, and consumers here are gradually realising the benefits of plantbased and are decreasing meat intake. Most notably, Sunfed Meats debuted their vegan beef and bacon to an audience of committed meat-eaters at Meatfest last year, and incredibly, theirs was the most popular stand at the entire festival.

6. Germany, 7. Sweden, 8. Switzerland, 9. Canada, 10. Ireland

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Survey Reveals Top Countries & Cities in the World for Veganism in Our Post COVID World - vegconomist - the vegan business magazine

Vegans pelted with KFC chicken legs as they protest outside butchers – Metro.co.uk

Protesters in Stoke-on-Trent were filmed and taunted as they were hit with chicken on Saturday

Vegan activists were pelted with KFC chicken legs as they staged a friends not food demonstration outside a butchers last weekend.

Stoke-on-Trent animal rights activists (STAR) say they were taunted and filmed by people in a passing car when they protested outside Wayne Walker Quality Meats in Longport on Saturday.

Bradley Shaw, 22, who was part of the demonstration, told Stoke-out-Trent Live staff at the butchers gave us a bit of stick and told us to clear off when the group first arrived.

The workers eventually relented and had a civil conversation with protesters when they realised we werent going to leave but things became hostile when a car drove around a roundabout at the scene on Davenport Road.

Bradley said: At one point a car went around the roundabout and we were hit by a chicken leg. Theres a KFC just up the road so I think they had seen us and gone there and decided to taunt us.

We could see their mates filming in the car and hear them shouting and laughing. They just think its a bit of fun to have a go at a vegan.

The activist has admitted hes used to getting ridiculed for his beliefs, naming veganism a controversial topic.

Despite the chicken leg incident, he said demonstrators had a good response from the community overall and STAR are now planning future events.

Police were called to the protest on Saturday, but the activists were not doing anything illegal.

Michael Patrick, shop manager at Wayne Walkers, said he doesnt have a problem with what they stand for but believes they shouldnt push their agenda onto other people.

He said: Their biggest problem seemed to be that we sell meat at low prices but we dont actually slaughter any animals.

Thankfully the protest didnt put off any of our customers. In fact, it was more like free publicity.

Get in touch with our news team by emailing us atwebnews@metro.co.uk.

For more stories like this,check our news page.

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Vegans pelted with KFC chicken legs as they protest outside butchers - Metro.co.uk

Would going vegan save the planet? – Hoard’s Dairyman

Half of 1% of all global greenhouse gases are a result of animal-sourced foods we produce and consume in the U.S. I know in the public, and in the media, the notion is out there that what we eat here has a tremendous impact on global climate, but heres another perspective from the Environmental Protection Agency (EPA), said Frank Mithloehner, a professor and air quality specialist at the University of California-Davis.

Carbon dioxide, methane, and nitrous oxide have the potential to cause global warming. Those gases trap the heat and keep it warm, and we couldnt survive without them, Mithloehner explained in the webinar Feeding people without wasting the planet, part of the Real Science lecture series by Balchem Animal Nutrition.

These gases can produce different levels of warmth by trapping heat, just like drinking the same amount of a soda, beer, or vodka has different impacts on a person. The gases have different potencies. They form a blanket over the atmosphere, which keeps the heat from the sun close to the earths surface.

But now the blanket is getting too thick, and the question is, How can we reduce these greenhouse gases? he said.

More people, more food needed

The impact of greenhouse gas ties into both our plant and animal agriculture production choices.

Im now 50. Our worlds population is at 7.6 billion, and when Im old well be at 9.5 billion, which means that throughout my lifetime the human population tripled. But the natural resources to feed these people will not have tripled. This leads us to make important decisions around how we grow our food.

The more efficient a farm uses their resources, the lower the carbon footprint. Farmers have achieved this by making four main changes.

We have improved reproduction, veterinary practices, genetics, and diet. North America has the lowest carbon footprint in the dairy sector in the world, not the highest, as the media wants you to believe. We have record low numbers of animals needed to produce the same amount, he said. We have done so much more with so much less, and that is a truly remarkable achievement.

Planes versus food

When presented with the question if we could eat ourselves out of climate change, he compared numbers a person eating vegan for a year would save 0.8 tons of carbon dioxide equivalent (CO2e). In comparison, one trans-Atlantic flight emits 1.6 tons CO2e. If everyone in the U.S. gave up meat for one day a week, it would reduce greenhouse gas by 0.3%. If the entire nation went vegan, it would save 2.6% of greenhouse gases.

However, he noted, for every one vegan, there are five former vegans, so he is skeptical veganism is a diet people are able to maintain.

The area where people can make the biggest impact on greenhouse gases is in food waste. Currently 40% of all food produced in the U.S. goes to a landfill, and that percentage is the same as in developed and developing countries even in Africa.

This percentage of waste holds true globally, and I think we can do better. Much better, he said.

The author and her family own and operate a sixth-generation dairy farm near St. Johns, Mich.

Excerpt from:
Would going vegan save the planet? - Hoard's Dairyman

R&D Activities to Fast-track the Growth of the Healthcare Nanotechnology (Nanomedicine) Market Between 2015 2021 – The Daily Chronicle

Persistence Market Research recently published a market study that sheds light on the growth prospects of the global Healthcare Nanotechnology (Nanomedicine) market during the forecast period (20XX-20XX). In addition, the report also includes a detailed analysis of the impact of the novel COVID-19 pandemic on the future prospects of the Healthcare Nanotechnology (Nanomedicine) market. The report provides a thorough evaluation of the latest trends, market drivers, opportunities, and challenges within the global Healthcare Nanotechnology (Nanomedicine) market to assist our clients arrive at beneficial business decisions.

The Healthcare Nanotechnology (Nanomedicine) market study is a well-researched report encompassing a detailed analysis of this industry with respect to certain parameters such as the product capacity as well as the overall market remuneration. The report enumerates details about production and consumption patterns in the business as well, in addition to the current scenario of the Healthcare Nanotechnology (Nanomedicine) market and the trends that will prevail in this industry.

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The Healthcare Nanotechnology (Nanomedicine) market report Elucidated with regards to the regional landscape of the industry:

The geographical reach of the Healthcare Nanotechnology (Nanomedicine) market has been meticulously segmented into United States, China, Europe, Japan, Southeast Asia & India, according to the report.

The research enumerates the consumption market share of every region in minute detail, in conjunction with the production market share and revenue.

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The competitive expanse of this business has been flawlessly categorized into companies such as

Key players in the global nanomedicine market include: Abbott Laboratories, CombiMatrix Corporation, GE Healthcare, Sigma-Tau Pharmaceuticals, Inc., Johnson & Johnson, Mallinckrodt plc, Merck & Company, Inc., Nanosphere, Inc., Pfizer, Inc., Celgene Corporation, Teva Pharmaceutical Industries Ltd., and UCB (Union chimique belge) S.A.

Key geographies evaluated in this report are:

Key features of this report

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Exclusive details pertaining to the contribution that every firm has made to the industry have been outlined in the study. Not to mention, a brief gist of the company description has been provided as well.

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The Healthcare Nanotechnology (Nanomedicine) market report enumerates information about the industry in terms of market share, market size, revenue forecasts, and regional outlook. The report further illustrates competitive insights of key players in the business vertical followed by an overview of their diverse portfolios and growth strategies.

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Some of the Major Highlights of TOC covers:

Excerpt from:
R&D Activities to Fast-track the Growth of the Healthcare Nanotechnology (Nanomedicine) Market Between 2015 2021 - The Daily Chronicle

Korean study examines the combined impact of aspirin, metformin, and statin’s impact on lung cancer risk – The Cancer Letter

publication date: Sep. 18, 2020

The combined use of aspirin, statins, and metformin is associated with decreased lung cancer incidence and mortality, according to a study published in the Journal of Thoracic Oncology, the journal of the International Association for the Study of Lung Cancer.

All three medications are commonapproximately 35 million people take a statin to control cholesterol; more than 120 million people take metformin to control diabetes and between 6 and 10 million people take aspirin daily.

The aim of this study was to investigate the associations of aspirin, metformin, and statins with lung cancer risk and mortality using population-based nationwide cohort data from The Korean National Health Insurance Services database was used in the present study. The KNHIS is a universal health care system that covers the entire Korean population of 50 million.

To our knowledge, no study has evaluated aspirin, statins, and metformin use and their combined impact on lung cancer incidence and mortality, lead study author Dong Wook Shin, of the Sungkyunkwan University School of Medicine, said in a statement.

Shin and his colleagues (Jihun Kang and Su-Min Jeong) examined 732,199 Koreans from the Korean National Health Insurance Services database. The patients were followed between January 2004 and December 2013. Lung cancer incidence and mortality were identified using a registered lung cancer diagnosis code (ICD-10 code C34) and the Korean National Death Registry.

To address the combined associations of these cardiovascular drugs with lung cancer risk and mortality, the researchers categorized the cohort into eight groups, based on exposure to aspirin, statins, and metformin.

Combined use of aspirin, statins, and metformin was associated with decreased lung cancer incidence (aHR 0.83, 95% CI, 0.690.99) and mortality (aHR 0.83, 95% CI, 0.700.99) compared with non-users.

When these cardiovascular drugs were used in combination, their protective associations with lung cancer risk and related mortality were augmented and the magnitude of effect increased with increasing duration of medication use, Shin said in a statement.

During 2012-2013 (the most recent period in the study), study participants taking all three medications were 3.4% (23,163 out of 676,520).

Interestingly, the inverse association of combined use of aspirin, statins, and metformin was prominent, and the longer the duration of combined use, the more protective the association.

This finding is in line with a study demonstrating that aspirin and metformin synergistically inhibit lung cancer cell proliferation by activating AMP-activated protein kinase, which plays a critical role in regulation of lipogenesis in cancer cells, Shin wrote.

Shin theorized that concomitant use of aspirin, statins, and metformin concurrently inhibits multiple pathways related to lung cancer cell growth and proliferation resulting in favorable associations with lung cancer risk and mortality.

Cigarette smoking associated with worse outcomes for bladder cancer patients after surgery

Patients treated for bladder cancer with a surgery known as radical cystectomy have worse outcomes if they are smokers, according to a systematic review and meta-analysis by Keck Medicine of USC. The study appeared in the Journal of Urology.

This study is important because while it is known that tobacco smoking is the leading cause of bladder cancer, this is the first study to suggest that smoking puts bladder cancer patients at risk after diagnosis, Giovanni Cacciamani, lead author of the study and assistant professor of research urology at the Keck School of Medicine of USC, said in a statement.

More than 500,000 cases of bladder cancer are diagnosed each year worldwide. When the cancer is large or has spread beyond the bladder, patients are typically treated with chemotherapy followed by a radical cystectomy.

Cacciamani and fellow Keck Medicine researchers searched databases to select 17 studies that reported on the impact of tobacco smoking on chemotherapy response and survival outcomes of 13,777 patients following radical cystectomy. Of these patients, 40.8% were active smokers at the time of the surgery, 14.1% former smokers and 45.1% had never smoked or were not smoking at the time of the surgery.

The study showed that active smokers responded worse to chemotherapy and had higher mortality rates, both in general and specifically from bladder cancer, and a higher rate of bladder cancer recurrence than patients who never smoked or were not smoking at the time of surgery.

Former smokers also fared worse in these categories than those who had never smoked, even though the differences were less significant.

The research suggests that as long as a person is not smoking at the time of chemotherapy and surgery, they might do better, Cacciamani said in a statement.

He also recommends that physicians monitor smokers more carefully post-surgery than other patients because they are more at risk for complications or death.

In addition, the study authors recommend that future studies or clinical trials involving bladder cancer chart patients smoking status to create a more accurate picture of what factors affect cancer survival and recurrence.

Other Keck Medicine physicians who authored the study include Mihir Desai, Parkash Gill, Inderbir Gill, and Hooman Djaladat. Saum Ghodoussipour who is a former surgical oncology fellow with Keck Medicine, co-authored the study.

Researchers from medical institutions in Austria, Italy and Russia also participated in the study.

Partner Therapeutics begins phase III study of leukine + ipilumimab and nivolumab front-line melanoma

The EA61411 study conducted by ECOG-ACRIN Cancer Research Group has begun its phase III portion.

Partner Therapeutics Inc. sponsors the study.

EA6141 (NCT02339571) is a randomized controlled study of Leukine (sargramostim, yeast derived rhu-GM-CSF) in combination with ipilimumab and nivolumab for the front line treatment of melanoma.

The restart was based on results of ECOG-ACRINs planned interim efficacy and safety analysis of survival data from the first 250 patients enrolled in the study. FDA granted orphan drug status to Leukine in Sept. 2019, for the potential treatment of stage IIb-IV melanoma.

EA61411 is led by study chair F. Stephen Hodi, director of the Center for Immuno-Oncology at Dana-Farber Cancer Institute and study Co-Chair Ahmad Tarhini, professor of oncologic sciences and director of Cutaneous and Clinical Translational Research at H. Lee Moffitt Cancer Center and Research Institute.

GM-CSF has unique immunomodulatory properties that have the potential to substantially benefit patients with cancer, Hodi said in a statement. He added This study in the front line setting is intended to confirm and broaden the findings in the randomized phase II trial EA1608, which demonstrated improved efficacy and toxicity when sargramostim was added to ipilimumab.

ECOG-ACRIN launched the phase II/III EA6141 study in Sept. 2015. In the study, patients with stage III/IV unresectable melanoma are randomized to receive standard of care treatment with nivolumab and ipilimumab with or without sargramostim. The primary endpoint is overall survival. ECOG-ACRIN planned for the interim trial pause after 240 patients were enrolled, to assess efficacy.

The group paused enrollment in June 2017 and the interim analysis is now complete. Based on the findings of the interim analysis, the ECOG-ACRIN Data Safety Monitoring Committee has given the go ahead to start the enrollment into the phase III portion of the study. The total planned enrollment is 600 patients. The study remains blinded and no data will be released until completion.

The prior data with sargramostim supporting improvement in survival and reduction in immune-related toxicity, as observed in the E1608 study, highlights the importance of further clinical evaluation in combination with checkpoint inhibitors, Tarhini said in a statement.

ECOG-ACRIN previously reported results of Study E1608, a phase II study in which patients with advanced stage melanoma received a combination of sargramostim and ipilimumab or ipilimumab alone2. Among 245 patients, the addition of sargramostim led to longer survival (median 17.5 vs 12.7 months, HR 0.64).

Leukine is not approved for the treatment of melanoma.

Despite progress, adolescents and young adults face substantial cancer disparities by race/ethnicity

A new report examining cancer in adolescents and young adults defined as diagnoses occurring during ages 15 to 39, provides updated estimates of the contemporary cancer burden in this age group, predicting that 89,500 cases and 9,270 deaths will occur in 2020 in the United States. The report appears in CA: A Cancer Journal for Clinicians.

AYAs with cancer are frequently grouped with older or younger patient populations and/or presented in aggregate, masking the wide heterogeneity in cancer occurrence within this population. To address this issue, American Cancer Society investigators also examined cancer incidence, survival, and mortality among AYAs by race/ethnicity and for smaller age groups (15-19, 20-29, and 30-39).

Cancer incidence rates among AYAs are highest in those who are non-Hispanic white (83 per 100,000 population during 2012-2016) and lowest in those who are Asian/Pacific Islander (54 per 100,000 population) for both sexes. This reflects higher rates in non-Hispanic white AYAs for thyroid cancer, testicular tumors, and melanoma compared to other major racial/ethnic groups. Unlike adults ages 40 and older, however, female breast cancer incidence rates in non-Hispanic Black AYAs are 14% higher than those in non-Hispanic white AYAs (25.9 vs 22.3 per 100,000 population).

The authors also note that despite patterns in overall incidence, cancer mortality rates are highest in non-Hispanic Black AYAs, particularly females (12.6 per 100,000 vs 9.2 in non-Hispanic white persons), reflecting substantial survival disparities compared to those who are non-Hispanic white. The largest 5-year cancer-specific survival disparities occur among those who are non-Hispanic Black compared with non-Hispanic whites for acute lymphocytic leukemia (57% vs 71%, respectively) and female breast cancer (78% vs 89%, respectively).

By age group, the cancer incidence rate in AYAs increased during the most recent decade (2007-2016) overall but showed signs of stabilizing among men in their 20s. The rise is largely driven by thyroid cancer incidence rates, which rose by approximately 3% annually among those aged 20 to 39 and 4% among those aged 15 to 19 years. Incidence increased for several cancers linked to obesity, including kidney (3% across all age groups), uterine corpus (3% in group aged 20-39 years), and colorectum (0.9%-1.5% in the group aged 20-39 years).

In contrast to incidence, cancer mortality rates among AYAs for all cancers combined declined in the past decade (2008 through 2017) by 1% across sex and age groups except females aged 30 to 39, among whom rates remained stable due to a flattening of declines in breast cancer mortality. Mirroring incidence, mortality rates increased during the most recent 10 data years (2008-2017) for colorectal and uterine corpus cancers.

Other highlights from the report include:

Adolescents (aged 15-19 years) are more likely to be diagnosed with cancers associated with childhood, such as Hodgkin lymphoma, while those aged 20 to 39 years are more likely to be diagnosed with adult cancers, such as breast. Thyroid cancer is the only cancer predicted to rank among the three most commonly diagnosed cancers in each AYA age group in 2020.

Leukemia continues to be the leading cause of cancer death in ages 15 to 29 years. Among ages 30-39 years, breast (women) and colorectal (men) cancers are the leading cancer causes of death.

Melanoma incidence rates during 2007-2016 rapidly declined in ages 15 to 29 (4%-6% annually, on average). However, among ages 30-39 years, rates declined only slightly among men and remained flat among women.

Overall 5-year relative survival in AYAs for all cancers combined (83%-86% across age groups) is similar to that in children (84%), but masks lower survival for several cancer types, such as acute lymphocytic leukemia (ALL; 60% vs 91%, respectively).

The report notes an increasing body of evidence that tumors in AYAs are molecularly distinct from those in younger or older populations, suggesting differences in etiology and in treatment options. In addition, studies have shown that compared to childhood cancer survivors, AYAs have a higher risk of progression and death from their original cancer. Compared to older cancer patients, AYAs have a higher risk of long-term and late effects including infertility, sexual dysfunction, cardiovascular disease, and other future cancers. However, further research in these areas is needed.

The authors say that progress in reducing cancer morbidity and mortality among AYAs could be improved with more equitable access to health care, as AYAs are more likely than other age groups in the U.S. to be uninsured. Increased clinical trial enrollment, expanded research, and improved awareness among clinicians and patients of early symptoms and signs of cancer could also accelerate progress.

Study: Rubbery properties help RNA nanoparticles target tumors efficiently and quickly leave body

A new study by researchers at The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute demonstrated that RNA nanoparticles have elastic and rubbery properties.

These properties explain why these particles target tumors so efficiently and why they possess lower toxicity in animal studies.

RNA nanoparticles show great promise for the targeted delivery of anticancer drugs. Understanding their structure and behavior is essential for their possible future use.

This study, published in the ACS Nano, reveals that RNA nanoparticles have elastic and rubbery properties that enable the molecules to stretch and return to their normal shape. Researchers say that these properties could help the particles target tumors by enabling them to slip through the poorly formed walls of tumor blood vessels and enter a tumor mass.

The researchers further proved that the same rubbery properties enable the RNA nanoparticle to slip through the kidney filters to excrete into the urine half hour after systemic injection, thereby eliminating them from the body relatively quickly. That, in turn, could reduce retention of the anticancer agent in vital organs, lowering an agents toxicity.

We show that RNA nanoparticles have a flexibility that allows for the assembly of molecular structures that have stretchable angles, study leader and corresponding author Peixuan Guo, professor in the College of Pharmacy and the Sylvan G. Frank Endowed Chair in Pharmaceutics and Drug Delivery, said in a statement. Guo also is in the OSUCCC James Translational Therapeutics Research Program.

These findings demonstrate the rubbery properties of RNA nanoparticles and why these molecules hold great promise for industrial and biomedical applications, especially as carriers for targeted delivery of anticancer drugs, Guo, who directs Ohio States Center for RNA Nanobiotechnology and Nanomedicine, said in a statement.

For this study, Guo and colleagues tested the elasticity of nucleic acid polymers by stretching and relaxing individual RNA nanoparticle, while subjecting RNA nanoparticles to elasticity studies using dual-beam optical tweezers built in Guo lab. They used animal models to study the biodistribution, excretion and retention of RNA nanoparticles. This included measuring excretion of the particles in urine, along with the study on the effect of their shape and size.

Key findings include:

RNA nanoparticles are stretchable and shrinkable, like rubber, even after repeated extension and relaxation with multiple repeats by optical tweezers.

In animal models, RNA nanoparticles show stronger cancer targeting and lower accumulation in healthy organs when compared to gold and iron nanoparticles of similar size.

Also in animal models, within half an hour after systemic injection, RNA nanoparticles that were 5, 10 and 20 nm in size were filtered by the kidneys and retained their original structure in urine, even though the upper limit of kidney pore size for filtration is generally 5.5 nm. This suggests that the larger RNA nanoparticles slipped like rubberly and amoeba through filtration pores, then returned to their original size and shape in urine.

Other researchers involved in this study were Chiran Ghimire, Hongzhi Wang, Hui Li, Mario Vieweger and Congcong Xu, The Ohio State University.

Link:
Korean study examines the combined impact of aspirin, metformin, and statin's impact on lung cancer risk - The Cancer Letter

RNA Nanoparticles Rubbery Properties Help Them To Target Tumors – Technology Networks

A new study by researchers at The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC James) shows that RNA nanoparticles have elastic and rubbery properties that help explain why these particles target tumors so efficiently and why they possess lower toxicity in animal studies.

RNA nanoparticles show great promise for the targeted delivery of anticancer drugs. Understanding their structure and behavior is essential for their possible future use.

This study, published in the journalACS Nano, reveals that RNA nanoparticles have elastic and rubbery properties that enable the molecules to stretch and return to their normal shape. Researchers say that these properties could help the particles target tumors by enabling them to slip through the poorly formed walls of tumor blood vessels and enter a tumor mass.

The researchers further proved that the same rubbery properties enable the RNA nanoparticle to slip through the kidney to excrete into the urine a half-hour after systemic injection, thereby eliminating them from the body relatively quickly. That, in turn, could reduce retention of the anticancer agent in vital organs, lowering an agents toxicity.

We show that RNA nanoparticles have a flexibility that allows for the assembly of molecular structures that have stretchable angles, says study leader and corresponding authorPeixuan Guo, PhD, professor in the College of Pharmacy and theSylvan G. Frank Endowed Chair in Pharmaceutics and Drug Delivery. Guo is also in the OSUCCC JamesTranslational Therapeutics Research Program.

These findings demonstrate the rubbery properties of RNA nanoparticles and why these molecules hold great promise for industrial and biomedical applications, especially as carriers for targeted delivery of anticancer drugs, says Guo, who directs Ohio StatesCenter for RNA Nanobiotechnology and Nanomedicine.

For this study, Guo and his colleagues tested the elasticity of nucleic acid polymers by stretching and relaxing individual RNA nanoparticle while subjecting RNA nanoparticles to elasticity studies using dual-beam optical tweezers built in Guo Lab. Finally, they used animal models to study the biodistribution, excretion and retention of RNA nanoparticles. This included measuring excretion of the particles in urine along with the study on the effect of their shape and size.

Key findings include:

Overall, Guo says, we believe these findings further support the development of RNA nanoparticles for targeted delivery of anticancer drugs or therapeutic RNA.

Reference: Ghimire C, Wang H, Li H, Vieweger M, Xu C, Guo P.RNA nanoparticles as rubber for compelling vessel extravasation to enhance tumor targeting and for fast renal excretion to reduce toxicity.ACS Nano 2020; doi:10.1021/acsnano.0c04863

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

Continued here:
RNA Nanoparticles Rubbery Properties Help Them To Target Tumors - Technology Networks

Pandemics and transhumanism – The Times of India Blog

The pandemic has forced authorities around the world to scramble for solutions within the realm of possibility. One of the more futuristic, radical solutions which is still relegated to the sidelines is transhumanism. It is a branch of philosophy that believes in transcending the limitations of the human population through technological augmentation. From hearing aids, pacemakers, bionic arms, the manifestations of transhumanism are very much present in our lives. However, the radical applications of being able to tweak biology to suit ones interests and needs at a commercial cost is yet to see the light of day. The basic tenet of transhumanism is extension of human life. Yet, eternal life comes across as a utopian thought where inadequate manufacturing of PPE kits for doctors and nurses have us jolted back to the harsh realities of current pandemic dwelling.

Since the globalized nature of modern capitalistic order and the consequent interconnectedness of our lives has made the possibility of frequent pandemics ever so plausible, we find ourselves at the juncture of a major shift towards increasing receptivity to transhumanist solutions. The famous American inventor and futurist Kurzweil wrote in his book The Singularity Is Near: When Humans Transcend Biology about a journey towards a meshing point of humans and machine intelligence The Singularity. He envisioned nanobots which allowed people to eat whatever they want while remaining healthy and fit, provide copious energy, ward off infections or cancer, replace organs and augment their brains. There will come a future where human bodies will carry so much augmentation that they would be able to alter their physical manifestation at will.

Even if the coronavirus fades off without wiping humans off the planet, it has given an eerie trailer of what future outbreaks might hold in store. Hence due security measures have to be pondered upon -whether in the labs, where deadly pathogens are being researched upon or in the malicious possibilities of a biowarfare. Frontline workers can be provided tech enhancements to ensure better armament against infectious, mutating viral diseases. Protective exoskeletons, real-time blood monitors for pathogens, can bid riddance to any temporary means of protection which are vulnerable against quality and efficacy issues.

In 2011, surgeons in Sweden had successfully transplanted a fully synthetic, tissue-engineered trachea into a man with late-stage tracheal cancer. The trachea was created entirely in a lab with tissue grown from the patients own stem cells inside a bioreactor designed to protect the organ and promote cell growth. Under transhumanism, artificial organs would be superior to ordinary donor organs in several ways. They can be made to order more quickly than a donor organ can often be found; would be grown from a patients own cells and hence wont require dangerous immunosuppressant drugs to prevent rejection.

As of 2018, prototypes of artificial lungs are also surfacing at the Galveston National Laboratory at the University of Texas Medical Branch, where the team spent the last 15 years developing the prototype. Upon completion, the bioengineered lungs were transplanted into four pigs. There was no indication of transplant rejection when the animals were examined at regular intervals for months after transplant. The researchers also observed that the bioengineered lungs became vascularized, establishing the necessary blood vessel networks to do its job. For diseases like covid-19, which affect a particular body organ, having an option of a bioengineered organ could very well be a safeguard.

But transhumanists are not just trying to extend human lives, they also want to revive them. They aim to merge bioengineering, AI capabilities, 3-D printing to resurrect the dead victims of any catastrophe much like the pandemic on our hands right now. Ways of dealing with grief at the loss of a loved one can possibly be placated with measures like interactive custom-holograms, social media feed powered by AI that could generate new messages based on the pattern of the old ones.

There are strong ethical considerations that also pop up in the discussion of transhumanism. Stefan Lorenz Sorgner, a German philosopher and bioethicist believes that processes like cryonics will go against most ecological principles given the amount of resources needed to keep a body in suspended animation post-death. Even though, transhumanism does not explicitly encourage breeding for the superiority of one specific group, the methods endorsed by some prominent transhumanists aim for physiological superiority. Considering that for the time being, solutions emanating will be heavy on the monetary end in the healthcare set-up, it could breed inequality in access. A huge gap in resources will be experienced in the society, as the affluent section amasses money and influence to set out an eternal timeline for themselves, coming at a lethal cost for the other half of the society.

Solving problems that will plague us in the future is a rising urge shared by leaders, philanthropists and billionaires around the world. This is why proponents like Zoltan Istvan fear the fact that the exponential rise of transhumanist technologies might leave governments fumbling to discuss and bring about policy directions to regulate and guard changes. Important questions like how far is too far? will need phased guidance as we have learnt from the chaotic response to systemic changes being implemented in the medical field during Covid-19. A conversation on transhumanism should not be put off any further and needs to permeate across different strata of stakeholders.

DISCLAIMER : Views expressed above are the author's own.

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Pandemics and transhumanism - The Times of India Blog

Testosterone Replacement Therapy Industry Market Current and Future Industry Trends, 2020 ? 2026 – AlgosOnline

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