Parvus Therapeutics, Novartis Partner on Novel Diabetes Nanomedicine – Drug Discovery & Development

Parvus Therapeutics, a biopharmaceutical company developing disease-modifying nanomedicines to halt or reverse autoimmune disease without causing general immune suppression, has entered into a license and collaboration agreement with Novartis for its lead Navacim for treating type 1 diabetes. Navacims constitute a novel pharmacological class of therapeutic comprised of nanoparticles (NPs) coated with disease-relevant peptide-major histocompatibility complexes (pMHCs) that alter the behavior of disease-causing T lymphocytes. Navacims are the first biopharmaceuticals to demonstrate in preclinical models the ability to restore immune tolerance in a disease-specific manner throughin vivoformation and expansion of regulatory T-cells (T-regs) without causing general immune suppression.

Under the terms of the agreement, Novartis receives exclusive, worldwide rights to use Parvus Navacim technology to develop and commercialize products for the treatment of type 1 diabetes (T1D) and will be responsible for clinical-stage development and commercialization activities. Parvus will be primarily responsible for conducting the ongoing preclinical work for the T1D program and filing the IND in collaboration with Novartis through a joint steering committee. Parvus has received an upfront payment and will receive research funding to support preclinical activities. In addition, Parvus is eligible to receive downstream development, regulatory, and sales milestone payments, as well as product royalties. Novartis has also made an equity investment in Parvus.

T1D Navacims are composed of an iron oxide nanoparticle conjugated with multiple copies of a peptide derived from a pancreatic autoantigen, presented in the context of an MHC molecule. Preclinical studies have shown that Navacims achieve their therapeutic effect by reprogramming cognate pathogenic T cells into tissue-specific beneficial T-regs and thereafter inducing their systemic expansion. The expanded T-regs target and suppress the autoimmune disease-causing immune cells, sparing other immune cells and restoring the immune system to the normal steady state. Navacims have the potential, therefore, to specifically treat the autoimmune disease without increasing the risk of infection.

This is a transformative collaboration for Parvus. We are excited by this strong endorsement of the science behind our Navacim platform, as well as the opportunity to collaborate closely with a globally recognized leader in the field of immunology and autoimmune disease, stated Janice M. LeCocq, CEO of Parvus. "This will augment our resources across the Navacim platform and accelerate the development of our T1D program. We are also pursuing the development of multiple Navacims that target autoimmune diseases where there is high unmet need for disease-modifying drugs without causing systemic immunosuppression.

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Parvus Therapeutics, Novartis Partner on Novel Diabetes Nanomedicine - Drug Discovery & Development

Nanomedicine Market Size Worth $350.8 Billion By 2025 | CAGR … – Press Release Rocket

Grand View Research, Inc. Market Research And Consulting.

According to new report published by Grand View Research,The global nanomedicine market size was estimated at USD 138.8 billion in 2016.Demand for biodegradable implants with longer lifetimes that enable tissue restoration is anticipated to influence demand.

The global nanomedicine market is anticipated to reach USD 350.8 billion by 2025, according to a new report by Grand View Research, Inc. Development of novel nanotechnology-based drugs and therapies is driven by the need to develop therapies that have fewer side effects and that are more cost-effective than traditional therapies, in particular for cancer.

Application of nanotechnology-based contrast reagents for diagnosis and monitoring of the effects of drugs on an unprecedented short timescale is also attributive drive growth in the coming years. Additionally, demand for biodegradable implants with longer lifetimes that enable tissue restoration is anticipated to influence demand.

As per the WHO factsheet, cancer is found to be one of the major causes of mortality and morbidity worldwide, with approximately 14 million new cases in 2012 and 8.2 million cancer-related deaths. Thus, demand for nanomedicine in order to curb such high incidence rate is expected to boost market progress during the forecast period.

Solutions such as nanoformulations with triggered release for tailor-made pharmacokinetics, nanoparticles for local control of tumor in combination with radiotherapy, and functionalized nanoparticles for targeted in-vivo activation of stem cell production are anticipated to drive R&D, consequently resulting in revenue generation in the coming years.

Biopharmaceutical and medical devices companies are actively engaged in development of novel products as demonstrated by the increasingly growing partnerships between leading enterprises and nanomedicine startups. For instance, in November 2015, Ablynx and Novo Nordisk signed a global collaboration and a licensing agreement for development and discovery of innovative drugs with multi-specific nanobodies. This strategic partnership is anticipated to rise the net annual sales of the products uplifting the market growth.

However, in contrary with the applications of nanotechnology, the entire process of lab to market approval is a tedious and expensive one with stringent regulatory evaluation involved thereby leading investors to remain hesitant for investments.

Full research report on nanomedicine market analysis:http://www.grandviewresearch.com/industry-analysis/nanomedicine-market

U.S. nanomedicine market by products, 2013 2025 (USD Billion)

Further key findings from the report suggest:

Therapeutics accounted for the largest share of market revenue in 2016 owing to presence of nanoemulsions, nanoformulations, or nanodevices

These devices possess the ability to cross biological barriers. Moreover, presence of drugs such as Doxil, Abraxane, and Emend is attributive for higher revenue generation

Presence of substantial number of products manufactured through the use of microbial sources can be attributed for the largest share

In-vitrodiagnostics is expected to witness lucrative progress as a result of R&D carried out in this segment

Introduction of nano-enabled biomarkers, vectors and contrast agents with high-specificity and sensitivity are attributive for projected progress

Clinical cardiology is expected to witness the fastest growth through to 2025 owing to development in nano-functionalization and modification of surfaces for increased biocompatibility of implants in treatment of late thrombosis

Moreover, an abundance of research publications and patent filings from European region with a share of about 25% in nanomedicine-related publications is supportive for revenue generation from European economies

Asia Pacific is estimated to witness the fastest growth over the forecast period

Factors responsible include government and regulatory authorities that have implemented a framework to encourage R&D collaborations and framework extension.

Key players operating in this industry include Pfizer Inc., Ablynx NV, Nanotherapeutics Inc., Nanoviricides Inc., Abraxis Inc., Arrowhead Research Inc., Celgene Corporation, Bio-Gate AG, and Merck

Active expansion strategies are undertaken by a number of the major market entities in order to strengthen their position

North America dominated the industry in 2016, accounting for a 42% of total revenue

Presence of key participants operating in the region are involved in collaborative activities are attributive for the largest share of North America in sector revenue

View more reports of this category by Grand View Research at:http://www.grandviewresearch.com/industry/pharmaceuticals

Grand View Research has segmented the nanomedicine market on the basis of product, application, nanomolecule type, and region:

Nanomedicine Product Outlook (Revenue, USD Billion; 20132025)

Therapeutics

Regenerative medicine

In-vitro diagnostics

In-vivo diagnostics

Vaccines

Nanomedicine Application Outlook (Revenue, USD Billion; 2013 2025)

Clinical Oncology

Infectious diseases

Clinical Cardiology

Orthopedics

Others

Nanomedicine Nanomolecule Type Outlook (Revenue, USD Billion; 2013 2025)

Nanoparticles

Nanoshells

Nanotubes

Nanodevices

Nanomedicine Regional Outlook (Revenue, USD Billion; 2013 2025)

Read Our Blog:Nanomedicine: Nanoparticles-An innovative solution for targeted drug delivery

About Grand View Research

Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, we offer market intelligence studies ensuring relevant and fact-based research across a range of industries, from technology to chemicals, materials and healthcare.

For more information: http://www.grandviewresearch.com

Media Contact Company Name: Grand View Research, Inc. Contact Person: Sherry James, Corporate Sales Specialist U.S.A. Email: Send Email Phone: 1-415-349-0058, Toll Free: 1-888-202-9519 Address:28 2nd Street, Suite 3036 City: San Francisco State: California Country: United States Website: http://www.grandviewresearch.com/industry-analysis/nanomedicine-market

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Nanomedicine Market Size Worth $350.8 Billion By 2025 | CAGR ... - Press Release Rocket

Nanomedicine enables all-in-one cancer treatment – nanotechweb.org

Cancer is a complex disease to treat, and yet the operating principle of many current treatments is to simply kill healthy cells a little slower than cancerous ones. In response, scientists at The University of Electronic Science and Technology of China have developed a sophisticated nanoparticle-based treatment. Their theranostic nanoparticles carry an anti-cancer drug cargo, and showcase multiple cutting-edge nanomedicine technologies to enhance the drug's efficacy, including selective drug delivery, photoactive agents, and even signal-jamming genetic material.

The researchers have designed each individual nanoparticle to be a toolbox for cancer therapy, able to passively and actively target tumours (Biomater. Sci. 2017 Advance Article). The nanoparticles can act as contrast agents for both magnetic resonance imaging and X-ray, they deliver a concentrated dose of anti-cancer drugs, and they also thwart the cancer's attempts at developing immunity to the drug. They even deliver a photosensitizer that can be used to specifically weaken cancerous tissue by photodynamic treatment.

Yiyao Liu and colleagues demonstrated the efficacy of their nanodevices in vitro and in vivo on a range of cell lines and on tumours in living mice. They found that their nanoparticle drug-delivery technique effectively stopped tumour growth, whereas tumours in mice treated with the drug alone grew at a rate half that of a control group that had not been treated.

The nanoparticles are complex, many layered spheres. Protected by a jacket of natural polymer is a nugget of silica, holey like a sponge and soaked in doxorubicin, a common anti-cancer drug, along with the photosensitizer. The polymer jacket is pH sensitive so that it falls off in the acidic microenvironment of the tumour, only then releasing the active cargo.

Doxorubicin has two flaws. Firstly, it works by slotting in-between DNA base pairs to stop the replication process needed for cells to divide. This kills cells that need to duplicate quickly, such as cancerous cells, but harms many healthy cell types too. Secondly, it triggers the body's natural defences, causing cells to over express p-glycoprotein, a microscale pump that removes toxic molecules like doxorubicin from cells, and making the drug less and less effective against cancer.

The scientists at The University of Electronic Science and Technology of China countered both of these flaws. Healthy cell exposure is reduced by the polymer jacket, which makes sure the drug is only released under the conditions expected in a tumour. The jacket itself is covered in signal-jamming RNA to inhibit the expression of the cellular pumps, keeping the doxorubicin trapped inside the cells to allow the drug to work for longer. This impressive display of multifunctional nanoparticle design and synthesis demonstrates the power of nanomedicine for producing synergistic effects, offering new solutions to previously unsurmountable problems.

Personalizing nanoparticles to better target tumours Optimising the killing of tumor cells by targeted CNTs Silica nanoparticles suppress tumour growth

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Nanomedicine enables all-in-one cancer treatment - nanotechweb.org

Nanomedicine Award 2017: applications are now open! – Cordis News

The European Technology Platform for Nanomedicine (ETPN) and the EU-funded project ENATRANS, announce the launching of the 3rd edition of the Nanomedicine Award, which aim to promote and reward two excellent innovative nanomedicine-based solutions that could bring significant benefits to patients, answering thereby unmet medical needs. The winners in 2 categories will be announced and rewarded during the BIO-Europe conference in Berlin in November 2017. Apply Now!

Open to companies as well as to academic and private researchers across the globe, candidates should: - present totally new approaches based on Nanomedicine for the diagnosis and/or therapy of human diseases - describe explicit and defined potential market.

Applications will be assessed by a panel of highly-qualified nanomedicine, pharma, medtech and investment specialists.

The Award ceremony will take place during BIO-Europe 2017 in Berlin (Germany), on 7 November 2017.

Both winners will benefit from a full registration to BIO-Europe 2017 including the participation in the partnering event and a public presentation of the awarded projects. In addition, they will be granted an individual session with the experts of the Translation Advisory Board (TAB, http://www.nanomedtab.eu), a presentation slot during the ETPN Annual Event 2018 as well as a 1-year free membership to the ETPN (www.etpnanomedicine.eu).

The Award is supported by the EBD Group, the leading partnering firm for the global life science industry, and Nanobiotix, a late clinical-stage nanomedicine company pioneering novel approaches for the treatment of cancer.

THE DEADLINE TO SUBMIT CANDIDATURES IS 15 AUGUST 2017. APPLY ONLINE AT http://nanomedicine-award.com/apply-now/

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Nanomedicine Award 2017: applications are now open! - Cordis News

Novartis signs collaboration deal with tiny Parvus for diabetes nanomedicine – FierceBiotech

Novartis, which has had a busy week for its CAR-T and NASH programs, today moved onto diabetes after penning a new pact with virtual Canadian biotech Parvus Therapeutics to use its leading tech.

Exact monetary terms werent given in the release, but Novartis gets exclusive, worldwide rights to use Parvus Navacims nanomedicine tech, specifically for diabetes patients with Type 1 (T1D), and will take on the clinical and sales work for this program.

On its side, privately owned Parvus will be primarily in charge of the ongoing preclinical work for the T1D program and filing an IND with Novartis.

Parvus has received an undisclosed upfront payment and will also gain a research funding boost to help out with its preclinical work. Biobucks have also been lined up, with Novartis in addition taking an equity investment in the biotech.

Navacims are made up of nanoparticles coated with disease-relevant peptide-major histocompatibility complexes. They are designed to change the behavior of disease-causing T lymphocytes.

Parvus says Navacims "are the first biopharmaceuticals to demonstrate in preclinical models the ability to restore immune tolerance in a disease-specific manner through in vivo formation and expansion of regulatory T-cells without causing general immune suppression, although they will need to go through many more years of clinical trials to assess efficacy and safety in humans.

But for Parvus, this is a major deal at an early stage from one of the biggest biomedical companies in the world, confirming its previously stated desire to team up with a Big Pharma.

This is a transformative collaboration for Parvus, said Janice LeCocq, CEO of Parvus. We are excited by this strong endorsement of the science behind our Navacim platform, as well as the opportunity to collaborate closely with a globally recognized leader in the field of immunology and autoimmune disease.

This will augment our resources across the Navacim platform and accelerate the development of our T1D program."

The company will also continue work on using Navacims against autoimmune diseases, notably where there is high unmet need for disease-modifying drugs that do not cause systemic immunosuppression.

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Novartis signs collaboration deal with tiny Parvus for diabetes nanomedicine - FierceBiotech

Nanomedicine: A Vast Horizon on a Molecular Landscape – Part IX, Organs-on-a-chip II – Lexology (registration)

This is the ninth article in a review series on Nanomedicine. We reviewed the major research and entrepreneurial development of nanomedicine and the relevant patent landscape (Part I and Part II). The first topic we discussed was Organs-on-a-chip (Part III). Here, we continue our discussion in this field with focus on entrepreneurial developments. We also have other reviews about nanoparticles for drug delivery (Part IV), cancer therapeutics (Part V), and bio-imaging (Part VI). We also included a discussion about functional nanoparticles: quantum dots (Part VII) and magnetic nanoparticles (Part VIII). As in the past, those patent documents cited in the article are summarized in a table at the end.

Recently, Draper announced a three-year agreement with Pfizer. This collaboration focuses on developing effective disease models for testing potential drug candidates based on microphysiological systems, also known as organs-on-a-chip.

The organs-on-a-chip technology is a three-dimensional microfluidic based multi-cell co-culture system that models the physiological, mechanical, and molecular environment of the human body and mimics the physiological functions of human organs. This technology offers unique in vitro disease models for new drug screening and toxicology testing. This technology has attracted attentions not only from academic institutes but also from the pharmaceutical industry. One of the main reasons for this interest is the potential cost and time savings for drug research and the development process. As required by the FDA drug approval process, new drug chemical entities are tested in animals before going into human Phase I testing for the drug approval process. The preclinical animal testing process is tedious and extremely expensive. Additionally, animal models are not always predictive for characterizing drug safety in humans. About 40% of drug compounds fail in Phase I clinical trials (Clinical Development Success Rates 2006-2015, BIO Industry Analysis, June 2016). To address these challenges, organs-on-a-chip has been proposed as a novel method to develop human disease models and replace preclinical animal testing.

We have briefly reviewed the research development and IP landscape in organs-on-a-chip. Here we would like to focus on the entrepreneurial developments in this field. As in the past, those patent documents cited in the article are summarized in the table at the end.

AxoSim Technologies

AxoSim is a New Orleans based startup launched in 2014. Its main pipeline is a Nerve-On-A-Chip, which is a 3D cell-based model mimicking living nerve tissue. It aims at preclinical prediction of neurological safety and efficacy in the early stages of drug development. This technology was developed from Dr. Michael J. Moores group at Tulane University (US 20150112244).

Draper

The Charles Stark Draper Laboratory is an American not-for-profit research and development organization, having a long history from 1932. In 2009, Draper initiated a new area of medical systems. Draper closely collaborated with scientists at MIT to develop microphysiological systems to emulate human organs and create disease models. At the end of 2016, Draper announced a 3-year agreement with Pfizer, using the organs-on-a-chip technology to facilitate pre-clinical drug development with a focus on personalized medicine. Currently Draper has built three microphysiological systems for modeling liver, vasculature and gastrointestinal organs (US 7,670,797, US 8,951,302, US 9,067,179, US 9,528,082).

Emulate Bio

Emulate Bio is a Wyss Institute spin-off company launched in 2014. It focuses on developing multiple organ-on-a-chip systems to model human physiological systems. The technology is based on discoveries in Dr. Donald Ingbers lab, using models of the lung, liver, intestine, skin and brain (US 8,647,861). This lab is also interested in other organ systems such as the kidney and heart. In 2015, Emulate collaborated with Johnson & Johnson and Merck using organs-on-a-chip for drug discovery and development processes. In 2016, Emulate announced a collaboration with Seres Therapeutics to investigate Novel Microbiome Therapeutics for inflammatory Bowel Disease.

Hepregen

Hepregen is a MIT spin-off company founded in 2007, based on a technique developed in Dr. Sangeeta Bhatias lab (US 6,133,030). Its main product, HepetoPac Assay, utilizes a micropatterned hepatocyte co-culture system to model the metabolic activities of a liver system and was released in 2013. Their other pipeline product is HepetoMune, targeting an inflamed human liver model.

HREL

HREL is a Merck supported company, which was incubated in New Jersey from 2007-2011. Its technology originated from Dr. Michael Shulers group at Cornell University (US 7,288,405 and US 8,748,180). In 2013, HREL launched three liver-on-a-chip products for human, rat and dog. HREL has also established a collaboration with Sanofi for pre-clinic drug development.

InSphero

InSphero is a Swiss company founded in 2009. They use a scaffold-free 3D cell culture technique to generate self-assembled microtissues, emulating human organ systems (US 9,267,103 and WO/2017/001680). Their current pipelines include liver, pancreas, tumor, and skin microtissue systems and in vitro toxicology and drug discovery services.

Nortis

Nortis is a Seattle based company, spun out of the University of Washington in 2012. Nortis developed a microfluidic kidney-on-a-chip for drug testing and launched its commercial product on 2015 (US 7,622,298 and US 20150240194A1).

Tara Biosystems

Tara Biosystems is a New York-based Columbia University spin out company founded in 2014. Their focus is on developing a heart-on-a-chip system. The technology is based on research from Dr. Gordana Vunjak-Novakovics group at Columbia University and Dr. Milica Radisics group at Toronto University (US 20170002330A1 and US 20160282338). Tara Biosystems uses a Biowire platform, to introduce electrical stimulation on a microchip to stimulate stem cells to mature into heart tissue. This microtissue mimics adult heart muscles, offering a platform for drug discovery, cardiac toxicology, and personalized cardiology.

TissUse

TissUse is a Berlin, Germany-based company developing a Multi-Organ-Chip platform based on technology discovered in Dr. Roland Lausters lab at Technische Universitat Berlin (US 20130295598). This company uses a multi-organ-chip as a platform to emulate human metabolic activities and accelerate the development of pharmaceutical, chemical, cosmetic, and personalized medical products. Currently, TissUse has announced their 2-Organ-Chip and 4-Organ-Chip products, involving simultaneously culturing from 2 to 4 different organ equivalents on a single chip connected to each other by perfusion channels or vasculature. Their next goal is to develop a human-on-a-chip system, with a larger number of organs cocultured on a single chip.

The Charles Stark Draper Laboratory

The Charles Stark Draper Laboratory

Massachusetts Institute of Technology

Massachusetts Institute of Technology

Wolfgang MORITZ;

Jens KELM

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Nanomedicine: A Vast Horizon on a Molecular Landscape - Part IX, Organs-on-a-chip II - Lexology (registration)

Protein corona: a new approach for nanomedicine design – Dove Medical Press

Back to Browse Journals International Journal of Nanomedicine Volume 12

Van Hong Nguyen, Beom-Jin Lee

Department of Pharmacy, Bioavailability Control Laboratory, College of Pharmacy, Ajou University, Suwon, Republic of Korea

Abstract: After administration of nanoparticle (NP) into biological fluids, an NPprotein complex is formed, which represents the true identity of NP in our body. Hence, proteinNP interaction should be carefully investigated to predict and control the fate of NPs or drug-loaded NPs, including systemic circulation, biodistribution, and bioavailability. In this review, we mainly focus on the formation of protein corona and its potential applications in pharmaceutical sciences such as prediction modeling based on NP-adsorbed proteins, usage of active proteins for modifying NP to achieve toxicity reduction, circulation time enhancement, and targeting effect. Validated correlative models for NP biological responses mainly based on protein corona fingerprints of NPs are more highly accurate than the models solely set up from NP properties. Based on these models, effectiveness as well as the toxicity of NPs can be predicted without invivo tests, while novel cell receptors could be identified from prominent proteins which play important key roles in the models. The ungoverned protein adsorption onto NPs may have generally negative effects such as rapid clearance from the bloodstream, hindrance of targeting capacity, and induction of toxicity. In contrast, controlling protein adsorption by modifying NPs with diverse functional proteins or tailoring appropriate NPs which favor selective endogenous peptides and proteins will bring promising therapeutic benefits in drug delivery and targeted cancer treatment.

Keywords: protein-nanoparticle interaction, protein corona, exchange of adsorbed protein, toxicity reduction, predictive modeling, targeting drug delivery

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Protein corona: a new approach for nanomedicine design - Dove Medical Press

Novartis signs collaboration deal with Parvus for diabetes nanomedicine – Pharmaceutical Business Review

PBR Staff Writer Published 20 April 2017

Pharma giant Novartis has acquired the exclusive, worldwide rights for Parvus Therapeutics Navacim technology for type 1 diabetes (T1D) treatment.

Novartishas also made an undisclosed equity investment inCanada-based Parvus.

Under the terms, Novartis will develop and market products made from the Navacim technology besides taking responsibility of its clinical-stage development and commercialization efforts.

Parvus CEO Janice M LeCocq said: This is a transformative collaboration for Parvus. We are excited by this strong endorsement of the science behind our Navacim platform, as well as the opportunity to collaborate closely with a globally recognized leader in the field of immunology and autoimmune disease.

"This will augment our resources across the Navacim platform and accelerate the development of our T1D program.

We are also pursuing the development of multiple Navacims that target autoimmune diseases where there is high unmet need for disease-modifying drugs without causing systemic immunosuppression.

Parvus, which has secured an upfront payment for the rights, will handle the existing preclinical activities for the T1D program. It will file the Investigational New Drug (IND) jointly with Novartis through a jointly formed steering committee.

The Canadian pharma will also get funding for its research that will back the preclinical activities of Navacim.

Further, it will be entitled to receivedevelopment, regulatory and sales milestone payments. Along with them, it will get product royalties from the Swiss pharma giant, Novartis.

According to Parvus, Navacims comprise nanoparticles (NPs) coated with disease-relevant peptide-major histocompatibility complexes (pMHCs) that modify the behavior of T lymphocytes which are known to cause the disease.

They are claimed by Parvus to have the ability to specifically treat the autoimmune disease without increasing the risk of infection.

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Novartis signs collaboration deal with Parvus for diabetes nanomedicine - Pharmaceutical Business Review

Keaney: Tips for staying motivated for a healthy lifestyle – Port Huron Times Herald

Cheryl Keaney, For the Times Herald 5:01 p.m. ET April 14, 2017

Using photographs or inspirational sayings are a couple ways to keep yourself on track for a fitness regiment.(Photo: Getty Images)

How often have you found yourself really motivated and gung-ho about getting in better shape and losing weight, then the next thing you know that feeling is gone?

You were doing great eating healthier, exercising more and consistently, and then the next thing you know youre picking up a pizza for dinner. What happens to our motivation and why does it go down the tubes? What can you do to help you keep your vision and stay motivated?

I think what often happens is that we lose sight of our goals, and we lose sight of why we want to achieve our goals. When you lose that vision, your motivation gets lost right along with it. There oftenare realizations like, Oh yeah, I was supposed to go for a walk this morning or Yes, Ill take fries with that.

Recently I have experienced my own struggles with maintaining motivation, and have noticed time and time again my clients struggling with it as well. Being that I was a competitive bodybuilder, I thought back to the days when I was on very strict diets and maintained high levels of discipline and motivation to achieve my goal of competing.How did I do it? Whats different now? I kept a vision of my goal and of myself being on that stage on competition day. That vision, that reminder of that goal day in and day out fueled my motivation and desire to achieve my goal. I always had my goal in mind when it came to making choices when I slept, what I ate, when and how often I exercised.

Keeping that vision of achieving my goal helped me stay on track and make progress towards my goal.

Imagine someone having a goal of building their own home. Do you think they just wake up one day and forget that theyre building a house? No, nor did I forget that I signed up for a competition that was only weeks away. I was putting David Campbells quote into action every day, Discipline is remembering what you want.

What can you do to accomplish this, to simply just remember and keep your goal and vision fresh in your mind?

Write down your goal and post it at home and work. Use a food and exercise journal to plan and schedule your days, and also how you feel. There is something about writing down your goals that allows for it to sink more into your subconscious mind than just having one in your mind. Its too easy to forget your goals if you dont have them written down. Signing up for a race or competition is also a great way of literally putting your vision in writing, for your signature is committing you to the goal.

Vision boards are a great way to keep your goals in mind. Cut out motivational quotes and pictures that remind you of your goal and what you want to achieve. When I competed, I had created a poster of pictures of female bodybuilders I was inspired by, along with motivating sayings. You also can look up motivational quotes and images online and save them to your desktop or phone, or print them out to post at home or work.

Plan, plan, plan and put it in writing! Get a calendar or planner and use it specifically for planning your workout days and what you are going to do. When its written down, you see it, and youre more likely to stick to doing it. Even better, choose a motivational calendar so you get an added dose of motivation.

Keep your goals in mind every day, in everything you do. Keep your vision, to believe and achieve, and you will.

Cheryl Keaney, the founder of Buff Bodies Bootcamp, is a personal trainer and fitness/nutrition specialist. Visit her website, http://www.got2workout.com. Contact her at cmkfit@gmail.com.

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Healthy lifestyle seminar planned for May 5 | Local | kearneyhub.com – Kearney Hub

KEARNEY Make the Switch, a seminar on adapting a healthier lifestyle, will be presented May 5 at the Hampton Inn at 507 Talmadge St. in Kearney.

Participants will learn why change is difficult, why change is often warranted and the seven stages of the empowerment model. By the end of the seminar, participants should be able to help patients/clients move to a higher level in the empowerment model, as well as to apply one or more techniques in overcoming hurdles to improving health status.

Registration is at 7:45 a.m., and the workshop will end at 3:30 p.m. Cost is $99. Continuing education credit is available for nurses, social workers, mental health practitioners, occupational therapists and respiratory therapists.

The presenter is Dorothy Yeager of Dorothy & Associates. Yeager has a masters degree in adult education and is certified in Family and Consumer Sciences by the American Association of Family and Consumer Sciences.

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Healthy lifestyle seminar planned for May 5 | Local | kearneyhub.com - Kearney Hub

Pitt’s Healthy Lifestyle Institute poised to be national model for how to personalize healthcare – NEXTpittsburgh

Pitt's Healthy Lifestyle Institute is developing innovative approaches for modifying lifestyle behaviors that detract from overall health. Photo credit: John Conroy.

Lets say youre visiting your doctor for a routine physical and he tells you to go easy on the salt shaker, or shed a few pounds.

Okay, you get itbut what you might not get in that doctors appointment is a strategy for how to do this, and in a way that is specific to your lifestyle and the challenges you face.

Now, a new initiative housed within the University of Pittsburghs School of Educationcalled the Healthy Lifestyle Instituteis actively working on bridging that gap, and much more, by developing innovative approaches for modifying lifestyle behaviors that detract from overall health.

Whats so innovative about it? For one, it integrates a massive amount of health-related research endeavors (focused on physical activity,nutrition and lifestyle changes) from Pitt centers, departments, laboratories and related divisions. The institute harnesses the collective efforts of top researchers, clinicians and thought leaders throughout the Pitt community, and brings these thoughtful minds together under the same umbrella to collaborate and share ideas that will potentially make a substantial impact on the wellbeing of our society, explains John Jakicic, the institutes founding director and chair of the School of Educations Department of Health and Physical Activity. Essentially, the goal is to help Americans live healthier and happier lives.

The initiatives multi-pronged approach not only allows for the integration and training of health care providers, it aligns with health-based community initiatives as well. Furthermore, and perhaps most critically, it gives individuals direct access to the tools they need to make lasting health and lifestyle changes.

Take, for example, the issue of smoking cessation, Jakicic cites. The institute is bringing resources together across many content expertise areas to solve this health issue. Pulmonologists [who focus on the respiratory system] are working together with addictive behavior specialists and others to test-pilot new intervention strategies. The institutes research will examine how biological factors such as genetics influence lifestyle behaviors, as well as how these factors impact chronic diseases and negative health outcomes.

Heres that ideabroken down into simple terms: Currently, your MD might tell you, My recommendation is to stop smoking, and before you leave my office, Ill give you some medication to help you. With the institutes new approach, that same doctor might instead say, My recommendation is to stop smoking, and before you leave my office, Ill give you a tool do to so. This tool will help you understand under what circumstances youre smoking and what your specific triggers are. Maybe that tool is an app, or an online program. In any event, thegoal is to get to the crux of the individuals reasons for wanting to smoke and guide them through situations that trip them up, and prevent them from succeeding.

Pittsburgh as a national prototype

University officials envision the institute becoming a leader in the development of behavioral modification interventions, a resource for understanding how lifestyle factors impact health, and a model for how universities can communicate internally.

Its pretty clear that what we have going on here is ahead of the curve in a big way, Jakicic says. This is important because the major research centers that are doing research on what is healthy gets translated into meaningful relationships for how to get care.

Precision health medicine

Key to the success of the institutes mission will be the implementation of new initiatives to enhance research capacity. We still need research, Jakicic comments. We still need to understand how to do some of this stuff . . . Were taking data in a research context, putting teams together and testing it out so the initiatives are based upon evidence, instead of just maybe its a good idea.

These initiativesor, centers and programs to be installed within various schoolswill bring new technologies into Pitt laboratories, improve understanding of biological influences on human behavior and foster collaborative efforts between Pitt and the broader community. Additionally, the institute will forge collaborative pursuits with nonprofit organizations and public schools throughout southwestern Pennsylvania.

The talent base here at the University of Pittsburgh is uniquely suited to address important and impactful clinical questions related to lifestyle factors, and bring the type of national impact that we are envisioning, Jakicic adds. The Healthy Lifestyle Institute will put the University of Pittsburgh and the City of Pittsburgh in a position to respond rapidly and effectively to future areas of scientific and clinical need regarding the application of lifestyle approaches to improve health.

Its all leading to a specific field of medical research and personalized care called precision health, which harnesses the power of technology and big data, and translates it into information focused on predicting and preventing disease, not just treating it. So in the future, when your physician tells you to eat healthier or exercise more, youll know how to do so in a way that is better suited to you.

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Pitt's Healthy Lifestyle Institute poised to be national model for how to personalize healthcare - NEXTpittsburgh

Humpday Health: Bodybuilding is about a healthy lifestyle – WWAY NewsChannel 3

WILMINGTON, NC (WWAY) Body building is not new. It started long ago, but today it has grown to be much more.

Now you have several divisions, Michael Broadway said. Theres womens physique, figure, mens physique, classic physique, and bikini. So now its broader and bigger.

No pun intended.

Michael Broadway is the coach of Team Broadway here in Wilmington and he says that to be a body builder, you have to have a certain mindset. But in addition to a mindset, being an athlete like this takes a lot of work. However, despite misconceptions, these athletes say theres more to body building than working out.

Its a very healthy lifestyle and its all of it combined but you cant just come in here and work out, you cant just take the supplements and you cant just eat, Adrian Gonzalez said. Its the whole lifestyle in general.

If youre ready for the work, you can be a body builder. Kristina Bell is a mom of three but still loves the lifestyle.

I love working out, its always been a part of my lifestyle, Bell said. Its a good stress reliever and it keeps me level and calm. It just makes me feel good and an endorphin rush.

The rush of endorphins comes when they hit the stage. For members of this team, theyre living a healthy lifestyle while building confidence.

I feel like its the best me when Im on point and on track, Saraa Sydnor said. Sometimes I dont want to struggle but I think thats what makes you stronger.

If you want to get involved in body building, you can visit the state website by clicking here.

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Humpday Health: Bodybuilding is about a healthy lifestyle - WWAY NewsChannel 3

A healthy lifestyle came naturally to me – The Prospector

Steve Jobs once said, The first 30 years of your life, you make your habits. When you are 30 and above, your habits make you.

The last time I ate a fast-food hamburger was about two months ago, and it was only because my 20-member family decided to go to Wendys.

I always complain to them about not having enough healthy eating habits. Since I was a little girl, I would eat fruits instead of candy and granola instead of ice cream. I am not sure why I would do that, but having a healthy lifestyle has always defined me, especially now that I understand the benefits of living.

These choices are what Ive become known for in my family. Whenever we have family reunions, I always keep in mind what I order or prepare for myself. I try to convince my immediate family to turn vegan, but my mother always tells me the same thing, Ests loca Grecia, quieres morirte de hambre. (Youre crazy, do you want to starve to death?).

Dont get me wrong, I have tasted the other side and I honestly have not liked it as much as the healthy side. But there have also been times in my life where I just start eating chocolates every day or drink too many sweetened teas.

There was even a time that I was over-eating a Mexican candy called Skwinkles. I was in elementary school and it was pretty much the only candy I ate during that period. I would eat one box each day and sometimes even two boxes per day. When I was starting middle school, I noticed my teeth color changed from white to light yellow. And this seemed weird because I had the habit of brushing my teeth after every meal. So my mother and I went to the dentist and found out the acid that was contained in the Skwinkles took out some whiteness of my teeth that I could never recover again.

Imagine my frustration after knowing that, because of my parents negligence, I was never going to have the whiteness that my teeth could have because of freaking acid candy. I think this was the precedent of me not ever eating candy for long periods of time, and if I did it is just one candy.

This experience made its mark on me. I now care about every single aspect of my health, always striving for a balance however. I practice yoga four times a week, I eat slowly and in portions, I drink a gallon of water per day, I am constantly meditating throughout the day (because is not only about physical health I care about, but mental health as well), and I try to have eight hours of sleep regularly.

Health does not represent just my habits; it has become my life. I do all these things because I feel good with myself afterward. I have experienced less stress by sleeping well, I feel happy with myself after every yoga practice I perform, and I feel with less depression once I know I ate well and did not go for the easy fast-food choice.

By caring about my health, I am caring about the future I pursue, which would be impossible to accomplish if I do not feel well. I care about my family, who loves seeing me happy. I care about my friends, who have seen me in my worst, and cherish my daily healthy decisions. By caring about my health, I am caring about myself, the first most important thing everyone should do in their lives.

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A healthy lifestyle came naturally to me - The Prospector

Brookfield Girl Scout teaches kids the importance of a healthy … – Danbury News Times

Photo: Lisa Weir / For Hearst Connecticut Media

Brookfield Girl Scout teaches kids the importance of a healthy lifestyle

BROOKFIELD - Children gather around high-school junior Erica Morey as she tells them why they should eat their fruits and vegetables. The kids sit in front of a poster board that displays the U.S. Department of Agricultures Choose my Plate graphic, which promotes a healthy diet.

Morey pulls out a box of plastic toy grapes, oranges and other foods. She instructs the kids to sort them into the categories: fruits, grains, proteins, vegetables, dairy and fats, oils and sweets.

Four-year-old Jack Dunkerton picks up a plastic pie and nearly puts it in a slot labeled fruit.

It has fruit in it, but is pie healthy for you? Morey asks.

Dunkerton moves it with the fats, oils and sweets.

The activity at the Brookfield Public Library Sunday morning was part of Moreys Girl Scout Gold Award project. The highest honor a Girl Scout can earn, the Gold Award is given to a girl who has created a project that will have a lasting impact on her community.

For her project, Morey wanted to encourage kids to live healthily in several classes during the spring.

I hope they have a better idea of [how] what theyre eating affects them, she said. And it can be fun. Its not just kale.

Morey has been a Girl Scout since kindergarten, and earlier completed her bronze and silver awards.

To kickoff the event, personal trainer Kerry Swift, whose daughter is in Moreys troop, led the kids in a series of exercises including squats, lunges and ab workouts.

Theres a huge obesity crisis in the country and the world, Swift said. Its important to get kids moving early and for them to enjoy fitness and make it a part of their daily routine.

The kids also decorated paper Get Well Bags that will go to Brookfield Social Services to be distributed to sick children. The bags, which Morey put together, include an animal word search, hand-drawn pictures to color, fuzzy socks and a brochure with information on healthy eating, exercise and how to avoid being sick.

The bags could go to kids with a range of illnesses, from the flu to cancer, Morey said.

It keeps them distracted and it gives them something to do, so they dont have to sit there and be sick, she said.

Kathy Morey, Ericas mother and troop leader, said her daughter, who is normally shy, has grown because of the project.

Shes taking charge and shes realizing she has to communicate with people, whether its over email or text or a phone call, she said.

Andrea Urvina, a Girl Scout Brownie leader whose daughter attended the event, is encouraging her troop to participate, and not just for their health. She also hoped they would be inspired as young women.

Its important for young girls to see older girls lead, Urvina said.

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Brookfield Girl Scout teaches kids the importance of a healthy ... - Danbury News Times

PGA Village Verano showcases a healthy lifestyle at Health Fair, 4/21 – Palm Beach Post

Since its debut, PGA Village Verano has attracted residents seeking an active, healthy lifestyle. Friday, April 21 homebuyers can experience the vibrant Verano lifestyle by attending the PGA Village Verano Health Fair from 10 a.m.2 p.m. at Veranos Club Talavera.

During the health fair, attendees can receive free fitness and health screenings while enjoying refreshments and presentations from health professionals. Many Treasure Coast medical and fitness vendors will have exhibits and there will be plenty of giveaways and door prizes.

While attending the health fair, homebuyers are invited to explore Club Talavera. One look at the outstanding Fitness Center the indoor lap pool, aerobics and yoga studio, weight room, basketball and bocce courts, Har-Tru tennis courts, massage therapy rooms, saunas, outdoor swimming pool and its little wonder that many Verano residents are in the best shape of their lives.

Few places offer the variety of recreational and fitness activities along with the world-class facilities and luxury homes that you find at Verano. Verano residents also enjoy walking trails, a dog park and, of course, golf at nearby PGA Village. With one of the best golf membership values in South Florida, Verano residents can enjoy access to 54 holes of championship golf, the PGA learning center and newly renovated PGA Village clubhouse.

At PGA Village Verano the social calendar is full and fun at the Club Talavera Social Club. From art classes and card games to happy hours, lectures and trips, Verano residents are on the go. The beautiful clubhouse features a billiards room, card rooms, a demonstration kitchen, a ballroom, library, lounge and an outdoor entertaining space with grills and fire pits overlooking the lake.

Award-winning developer, Kolter Homes offers an elegant collection of villa and single-family home designs for Verano.

Single-family homes offer two- and three-bedrooms many with a den, two-car garage and up to 3,181 square feet under air.

The Bella Vista Collection of Villa homes are perfect for the carefree lifestyle. Villa homes live large, offering two bedrooms plus a den, a two-car garage and 1,620 square feet under air.

New homes in PGA Village Verano are priced from the $200,000s to the $500,000s.

Kolter also has a limited number of move-in-ready homes that are available for immediate occupancy.

Address: The Model Park and Move-In-Ready homes are at 17127 S.W. Ambrose Way, Port St. Lucie, FL 34986

Hours: The Model Park and Quick-Delivery homes are open daily from 10 a.m.-6 p.m.

Prices: Single-family homes from $234,900, villas from $219,900

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PGA Village Verano showcases a healthy lifestyle at Health Fair, 4/21 - Palm Beach Post

A healthy lifestyle doesn’t mean missing out on the sweet life | Starts … – Starts at 60

There is research that shows you may start adding more sugar to your meals as you get older because your tastebuds become less likely to detect sweetness.

Even if your tastebuds are in tip-top condition, you may still be eating too much sugar. A recent study showed that 52 per cent of Australians consume more sugar than the standard global recommendation on intake. Its not hard to guess why, because sugar is in almost all edible products in one form or another.

Eating too much sugar doesnt just threaten your dental health, it can cause serious issues such as diabetes.

But it can be daunting to consider cutting down on sugar, and giving it up altogether can even cause physical withdrawal symptoms. So, if you can live a life without sugar, thats great, but for those who still love the sweet life, we have some tips to keep it as healthy as possible.

An easy way to start is to replace some of the sugar in your diet with one of the many sugar substitutes available. Stevia is one of the most popular as its a natural sweetener made from the leaves of the stevia plant thats found in Paraguay and Brazil. Stevia contains no calories, no sugar, no carbohydrates and is more than 200 times sweeter than regular sugar.

You can buy stevia from most supermarkets and it can be used in baked goods. It wont cause your blood sugar to spike.

Splenda has similar properties to stevia but is derived from sugar. Splenda is already added to many baked goods available in stores.

If those options dont satisfy your sweet tooth, you can try honey, which is jammed-pack with vitamins, minerals, and protein. Honey is a great sweetener for cold or hot drinks and baked goods. One of the added benefits of using it in baking is that honey attracts moisture so your cakes will stay moist for longer.

Replacing sugar in your life doesnt have to be hard. Challenge your taste buds by trying some of the tips offered and see what a difference a few healthy changes can make.

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A healthy lifestyle doesn't mean missing out on the sweet life | Starts ... - Starts at 60

Belarus’ Healthcare Ministry to launch website on healthy lifestyle – Belarus News (BelTA)

Valery Malashko

MINSK, 12 April (BelTA) The Belarusian Healthcare Ministry intends to create a website for promoting a healthy lifestyle. Belarusian Healthcare Minister Valery Malashko made the statement during the meeting with Michel Sidibe, Under-Secretary-General of the United Nations and Executive Director of the Joint United Nations Program on HIV and AIDS (UNAIDS), BelTA has learned.

Valery Malashko stressed the relevance and importance of education activities in the sphere of healthcare. The existing forms are not very effective while working with young people and do not always allow achieving the desired result. Therefore, the Belarusian Healthcare Ministry intends to create an information web portal which will be available for both young people and mature age citizens. One of the sections will be aimed at teenagers.

"We are trying to attract creative professionals in order to organize communication in ways young people are familiar with. I think it will allow us to promote our knowledge of healthy lifestyle," the minister said.

During the meeting the question of using methadone as part of a drug addiction replacement therapy was also brought up. Valery Malashko expressed hope that the number of relevant centers in Belarus will increase.

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Belarus' Healthcare Ministry to launch website on healthy lifestyle - Belarus News (BelTA)

The Nanomedicine Market to Grow at a CAGR of 17.1% During the Forecast Period 2017-2023 to Aggregate $392.80 … – Digital Journal

Nanomedicine has the potential to be the future in biotherapeutics replacing the older versions of drug delivery.

Bangalore, India - April 10, 2017 - (Newswire.com)

Infoholic Research LLP, a global market research and consulting organization, has published a study titled Global Nanomedicine Market Drivers, Opportunities, Trends, and Forecasts: 20172023.

According to Infoholic Research, nanomedicine is the future with new revenue stream in the healthcare industry. Nanomedicine could provide cost-effective novel therapies and diagnostics using the empowering capacity of nanotechnology applied in the healthcare industry. Nanomedicine could increase the efficiency and diminish the side effects unlike the other tender therapies for any particular condition. The elementary principles of this technique are based on the targeted drug delivery using nanoparticles (such as nanorobots), proper analysis using sensors and micro electro mechanical system (MEMS), and to diagnose in vivo biochemical activities. The result is an increasingly better understanding of the molecular biology of diseases leading to new targets for more specific and earlier diagnostic and therapeutic treatments. These new options will cause profound changes in future healthcare systems by enabling more personalized, regenerative, and remote medicinal activities. According to Infoholic Research, the Global Nanomedicine market is expected to grow at a CAGR of 17.1% during the forecast period 20172023 to touch an aggregate of $392.80 billion by 2023.

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@https://www.infoholicresearch.com/request-a-sample-report/?repid=4654

The Global Nanomedicine market is analyzed based on two segments application areas and regions. The regions covered in the report are the Americas, Europe, Asia Pacific, and Rest of the World (ROW). In the Americas region, the US and Canada are set to be the leading countries. The Europe is set to be the second leading region and holds more than 23% of the market share in 2016. Germany is one of the leading countries in Europe in terms of revenue. In Asia Pacific, Japan is the most attractive country for the players and holds huge business opportunities. The ROW is set to be an emerging market in the next 56 years.

The application areas covered in the report are Oncology, Cardiovascular, Neurology, Anti-inflammatory, Anti-infective, and other therapeutics. The Cardiovascular, Anti-inflammatory, and Neurology application segments are expected to gain more market share by 2023. The market is expected to be on a positive year on year growth rate, as the Cardiovascular and the Neurology segments have just started to see wide-scale adoption in the field of nanomedicine. The Oncology segment is expected to generate revenue of $144.00 billion by 2023.

Although, the market is experiencing a lack of well-defined FDA directives, which can restore standardization in the field of nanomedicines and related subjects, nanotechnology funding is expected to increase significantly during the forecast period with the increasing investments from government and private sectors. Victor Mukherjee, Assistant Manager (Research Healthcare) at Infoholic Research

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Further, the report also aims to cover the below points:

Provides an in-depth analysis of the key business opportunities in countries and verticals

Provides the complete details about the various types of nanomedicine drugs overview

Provides the complete details about the analysis of top 16 players

Provides industry outlook including current and future market trends, drivers, restraints and emerging technologies

Market is analyzed by countries the US, Germany, Japan, and Others

Press Release Service by Newswire.com

Original Source: The Nanomedicine Market to Grow at a CAGR of 17.1% During the Forecast Period 2017-2023 to Aggregate $392.80 Billion by 2023

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The Nanomedicine Market to Grow at a CAGR of 17.1% During the Forecast Period 2017-2023 to Aggregate $392.80 ... - Digital Journal

Ask the Doctors: Healthy lifestyle reduces risk of prostate cancer – Elmira Star-Gazette

Eve Glazier, M.D., and Elizabeth Ko, M.D 8:27 a.m. ET April 6, 2017

doctor with prostate cancer awareness ribbon(Photo: dolgachov, Getty Images/iStockphoto)

Dear Doctor

: Is there anything I can do to reduce my risk of prostate cancer? No one in my family has had cancer, but I just turned 55 and want to do whatever I can to stay healthy.

Answer: While there is no single approach to prevent prostate cancer, research has shown that certain lifestyle changes may reduce your risk of developing the disease. Considering that these behaviors also promote good health and well-being, you won't go wrong by adopting any or all of them.

Let's start with some facts about the disease. Prostate cancer is the second-most common cancer in men, right behind skin cancer. According to the American Cancer Society, one in seven men will get a diagnosis of prostate cancer during his lifetime.

However, that's not as dire as it sounds. Prostate cancers grow slowly and are slow to spread. As a result, survival rates of prostate cancer are high. The five-year survival rate is close to 100 percent. The 15-year survival rate is 95 percent.

The major risk factors for prostate cancer are age, race, family history, a diet high in red meat and animal fat, and tobacco use. While the first three can't be changed, they can alert you to be more vigilant.

About 70 percent of new cases of prostate cancer occur in men 65 and older. Men of African-American descent are at higher risk of developing the disease, and their cancers can be more aggressive. If you fall into those categories, and if cancer runs in your family, be sure to always include these facts in your medical history.

So how do you reduce your risk? Limit or skip red meat, dairy and animal fats. Opt for lean proteins like chicken, fish and turkey instead. Focus on healthy fats from plant-based sources like olive oil and nuts. We're sure you've heard it before, but that's because it's true: leafy greens, whole grains and fresh fruits and vegetables provide a wide range of vitamins, minerals and fiber.

Cooked tomatoes (which contain lycopene), cruciferous vegetables like broccoli and cauliflower, soy products and green tea are also recommended. Studies show that being obese or overweight is linked to higher rates of many kinds of cancer, including prostate cancer.

Regular physical activity, which not only burns calories and fat but also builds muscle mass, results in a lower -- and healthier -- body mass index. Do you use tobacco products? As physicians, we must ask you to please stop.

Tobacco plays a role in a daunting array of diseases and conditions, including prostate cancer. We know that quitting can be difficult and have given our own patients a hand in leaving tobacco behind. Don't be afraid to ask for help from your physician. Cancers that are caught early are more easily treated. That makes screening important.

Thanks to new understanding about slow-growing prostate cancers, many physicians will now recommend active surveillance in older men with slow-growing tumors.

Eve Glazier, M.D., MBA, is an internist and assistant professor of medicine at UCLA Health. Elizabeth Ko, M.D., is an internist and primary care physician at UCLA Health. Send your questions to askthedoctors@mednet.ucla.edu.

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Ask the Doctors: Healthy lifestyle reduces risk of prostate cancer - Elmira Star-Gazette

Premium Insight of Global Nanomedicine Market 2016-2021 – MilTech

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Market research reports for the Global Nanomedicine Sales Market included detailed segmentation of international, analysis of supply and demand trends, 5-year forecast of market growth, volumes of historic brand market, analysis of the production, importation and exportation, and transparent market methodology. In-depth studies regarding Global Nanomedicine Sales Market, with data from 2011 and projects of compound annual growth rates (CAGRs) are also used as basis for research. Lastly, there are examinations of the Global demand for the market and profiles of the major players of the industry.

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With all the data gathered and analyzed using SWOT analysis, there was a clearer picture of the competitive landscape of the Global Nanomedicine Sales Market. Sources for the future market growth were uncovered and outlying competitive threats also surfaced. There was strategic direction eminent in the market and this shows in the key trends and developments studied. By getting market background and using current norms, policies, and trends of other leading markets for cross-references, market data was completed.

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Table of Contents

Global Nanomedicine Sales Market Research Report 2021

1 Nanomedicine Sales Overview

1.1 Product Overview and Scope of Nanomedicine Sales

1.2 Nanomedicine Sales Segment by Types

1.3 Nanomedicine Sales Segment by Applications

1.4 Nanomedicine Sales Market by Regions

1.5 Global Market Size (Value and Volume) of Nanomedicine Sales (2011-2021)

2 Global Nanomedicine Sales Market Competition by Manufacturers

2.1 Global Nanomedicine Sales Production and Share by Manufacturers (2015 and 2016)

2.2 Global Nanomedicine Sales Revenue and Share by Manufacturers (2015 and 2016)

2.3 Global Nanomedicine Sales Average Price by Manufacturers (2015 and 2016)

2.4 Manufacturers Nanomedicine Sales Manufacturing Base Distribution and Product Types

2.5 Competitive Situation and Trends

3 Global Nanomedicine Sales Analysis by Regions

4 Global Nanomedicine Sales Analysis by Types

5 Global Nanomedicine Sales Market Analysis by Applications

6 Global Nanomedicine Sales Manufacturers Analysis

7 Nanomedicine Sales Technology and Development Trend

8 Research Findings and Conclusion

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