SEPC supports Arnold Palmer healthy lifestyles summer camp – TheProduceNews.com

August 24, 2017

In a continued effort to support communities in the Southeast, the Southeast Produce Council funded a six-week healthy lifestyles program for families at Arnold Palmer Hospital in Orlando, FL.

The summer session offered children and their families the opportunity to learn more about exercise, healthy eating, positive self-image, and more, while using a family-centered approach. Participants also set goals to achieve by the end of the six-week session. The program was led by Shaista Safder, who is certified in obesity care and management.

"We had a very successful healthy lifestyle summer program this year our best so far," Safder said in a press release. "Participants benefited immensely and were extremely grateful for the education and support they received. None of this would have been possible without our sponsor support from Southeast Produce Council, including Produce for Kids and FreshPoint. Our participant families definitely reaped the benefits of this partnership."

Southeast Produce Council members, FreshPoint Central Florida and Produce for Kids provided additional support, including a supply of fresh produce during the program, along with fruit- and vegetable-focused recipe ideas, cookbooks and kitchen gadgets.

We were very excited to help financially and actively in this exciting program to promote healthy lifestyle tips to all of the families that participated this year. These types of consumer educational programs are at the very core of what the SEPC is all about, David Sherrod, president and chief executive officer of the Southeast Produce Council, said in the press release. Arnold Palmer Hospital is one of the nations premier health facilities for children, and we proudly support all their tremendous efforts.

The Southeast Produce Council is also a Finish Line sponsor of Arnold Palmers Walk for Winnie, a year-long fundraising campaign culminating in a celebration event that benefits the Alexander Center for Neonatology at Winnie Palmer Hospital for Women & Babies.

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SEPC supports Arnold Palmer healthy lifestyles summer camp - TheProduceNews.com

Growth in the Global Nanomedicine Market 2017-2021 trends, forecasts, analysis – satPRnews (press release)

Global Nanomedicine Market 2017-2021

This Nanomedicine market research is an intelligence report with meticulous efforts undertaken to study the right and valuable information. The data which has been looked upon is done considering both, the existing top players and the upcoming competitors. Business strategies of the key players and the new entering market industries are studied in detail. Well explained SWOT analysis, revenue share and contact information are shared in this report analysis.

Download sample pages of this report:http://tinyurl.com/y7bs9wea

Data integration and capabilities are analyzed to support the findings and study the predicted geographical segmentations. Various key variables and regression models were considered to calculate the trajectory of Nanomedicine market. Detailed analysis is explained and given importance to with best working models.

Geographically, the segmentation is done into several key regions like North America, Middle East & Africa, Asia Pacific, Europe and Latin America. The production, consumption, revenue, shares in mill UDS, growth rate of Nanomedicine market during the forecast period of 2017 to 2021 is well explained.

The ongoing market trends of Nanomedicine market and the key factors impacting the growth prospects are elucidated. With increase in the trend, the factors affecting the trend are mentioned with perfect reasons. Top manufactures, price, revenue, market share are explained to give a depth of idea on the competitive side.

Each and every segment type and their sub types are well elaborated to give a better idea about this market during the forecast period of 2017 to 2021 respectively.

Download sample pages of this report:http://tinyurl.com/y7bs9wea

About Us:Key Market Insights is a stand-alone organization with a solid history of advancing and exchanging market research reports and logical surveys delivered by our numerous transnational accomplices, which incorporate both huge multinationals and littler, more expert concerns.

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Growth in the Global Nanomedicine Market 2017-2021 trends, forecasts, analysis - satPRnews (press release)

Are nano drug delivery and telehealth solutions a deadly combo for disease? – EPM Magazine

Incorporating telehealth solutions into new drug delivery technologies like nanomedicines can potentially give pharmaceuticals the edge they need to win the fight against disease.

Creating drug delivery systems that utilise telehealth solutions like smartphone technologies, Bluetooth, IoT, wearable technologies, and AI would help pharmaceutical companies save money in clinical trials by reducing the financial burden caused by poor medical adherence and provide better patient outcomes through real-time data analysis. Telehealth solutions provide physicians and clinical trial scientists direct access to their patient, and can provide them with valuable data that will improve their performance and the patients health. Access to real-time patient health data is an opportunity for pharmaceutical companies to develop a range of smart drug delivery systems that could potentially change the way an estimated 50% of the population deal with their chronic diseases.

With large numbers living with some form of chronic disease, pharmaceutical companies must incorporate telehealth tech into their drug delivery systems to collect real-time data and use the data to improve patient treatment, clinical trial outcomes and apply the data for further research.

The drug delivery systems available in todays market are honestly not that impressive. A Bluetooth-enabled inhaler, smart automatic injectors, and smart pills are definitely technologies that benefit patient care but lack innovative pizzazz. Bluetooth technology was first introduced in mobile phones in 2000. It has taken 17 years to implement the data-gathering technology into an inhaler/auto injector, often at times requiring user actions like downloading from an SD card. I am surprised it has taken this long for pharma to get where it is today, but there is truly hope on the horizon, with recent advancements in nanotechnology.

The future of pharmaceuticals and population health lies in the utilisation of telehealth solutions like the Internet of Nano Things (IoNT), wearables, smartphones and the latest drug delivery tech likesmart nanoplatforms, nanoparticles/nanomedicines, and nanosensors. These recent technological advancements in drug delivery should change the way we understand and cure diseases.

Northwestern University has developed a nanoplatform that can assess the effectiveness of nanomaterials in regulating gene expression. The nanoplatform allows scientists to observe nanomedicines and particle behaviour in an in vivo setting. Theres no doubt that the relationship between nanomedicines and IoNT is inevitable however there are issues like patient health risks and security that must be taken into account.

Whenever the internet is involved, the issue of security should be raised. Are nanomedicines saving patients lives, while also putting them at risk of body hacking? Although programmable particles are sending signals from within the patients body and providing beneficial information for the doctor/scientist, the idea that a signal can be hacked is a horrific reality. Nanoparticle manipulation is possible by gaining access to the particles using ultrasound and electromagnetic field waves making hacking feasible but extremely difficult and complex. The next question is what happens to the nanoparticles after treatment? Will they pose a later threat and become an access point for hackers?

Nanomedicines, after entering the human body, travel throughout reaching the organs, the bloodstream, the lungs and even crossing the semi-permeable membranes into cells delivering the drugs to exactly the right place at the right time. Their disbursement depends on size and programming. Nanoparticles are metal-based, carbon-based, composites, and dendrimers, and are excreted from the body via faeces and urine. The liver and spleen can also decompose them, however up to 30% can remain in the body for an extended period of time and potentially become an access point for hacking.

Combining telehealth solutions and nanomedicines will benefit the populations health by presenting effective treatments for chronic and deadly pathologies and provide scientists and doctors previously unattainable data for analysis. This previously elusive data has become available thanks to Northwestern Universitys Nanoplatform, which successfully provides imaging of the nanomedicines effectiveness on the MGMT gene, a chemo-resistant cancer gene. This data has already provided a better understanding of the nanomedicines mechanics and provided researchers with the best time, after treatment with nanomedicines, to administer chemotherapy.

Nanoparticles appear to be a solution that can improve the health of the population, however there are still potential risks for patients. Although most nanoparticles are tested in labs and in vitro, a few potential health risks have been observed. Risks like the creation of a protein corona (a shifting population of different molecules) can influence the immune defence system and mistakenly allow the corona to penetrate good non-targeted tissues. The clumping of protein molecules can also be linked to multiple pathologies, including amyloidosis. Some nanoparticles have also been linked to genetic mutations, DNA damage, and chromosomal alterations, however they are rarely attributed to all three at once. It is quite clear that more research and testing is required to truly understand the future of nanomedicine and its effects on the human body.

Nanomedicines target a specific area within the body, can delay activation and have the potential to relay real-time data for analysis. Scientists and doctors can finally have a real-time view of their treatments and understand the pathology and its interaction with the medicines, leading to data that will help the healthcare industry save lives, defeat disease, and save money. The benefits in combining telehealth solutions with nano drug delivery systems is evident and it is the colossal leap forward that the industry has been looking for in the never-ending fight with diseases like cancer.

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Are nano drug delivery and telehealth solutions a deadly combo for disease? - EPM Magazine

Female Hormone Optimization – Dr. Hagmeyer

Night sweats that keep you awake at all hours. Fatigue that makes everything such an effort even time with family and friends. Mood swings and lack of sexual desire that strain relationships with your partner. Anxiety, Depression,Thinning hair, wrinkles, weight gain, and dry skin that dont let you feel good about yourself.

Our endocrine system is devised of glands which produce and send hormones to all areas of our body to regulate essential function such as temperature, metabolism, reproduction, growth, immunity and aging. It stands to reason that this is the hub of vitality, longevity and well-being. With proper testing and monitoring, hormoneimbalances can be completely reversed with a Functional and Integrative approach and without standard prescribed medicines.

Our Seven-Step Natural hormone re-balancing and hormone make over program will address your major symptoms and ensure optimal results.

Here is just a glimpse into our Comprehensive Hormone Makeover and Restoration program. Read More

Complete a quick profile questionnaire to find out if this treatment is right for you!

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Female Hormone Optimization - Dr. Hagmeyer

Blood pressure classes begin Thursday – Laurinburg Exchange

LAURINBURG Scotland Health Care System is offering a free high blood pressure management program for senior adults created by the Community and Clinical Connections for Prevention and Health Branch of the North Carolina Division of Public Health.

Know It, Control It for Seniors begins on Thursday.

The class is a community-based blood pressure management program designed to help participants self-monitor their blood pressure and make healthy lifestyle changes to control high blood pressure. Trained blood pressure coaches teach this program using evidence-based strategies to manage cardiovascular disease.

Know It, Control It for Seniors is a community-based blood pressure management program designed to help participants self-monitor their blood pressure and make healthy lifestyle changes to control high blood pressure. Trained blood pressure coaches teach this program using evidence-based strategies to manage cardiovascular disease.

High blood pressure is the leading cause of heart disease, stroke and kidney disease in the United States, said Bines Community Educator of Scotland Health Care System. Knowing your blood pressure numbers can help you take action NOW to prevent or delay the development of more serious complications.

Almost one out of every three adults in the United States has been diagnosed with high blood pressure. Among adults 65 years and older, two out of three have high blood pressure and half of them do not have it under control. All adults should consult with a health care provider, learn their blood pressure numbers, learn to self-monitor their blood pressure and take steps to get healthy, said Bines.

Know It, Control It for Seniors classes are open to people who have been diagnosed with high blood pressure. During each class, blood pressure coaches will lead a discussion on a healthy habit that will help participants control their blood pressure. On class days, the blood pressure coach will also assist each participant with measuring and logging his/her blood pressure with the goal of having them become proficient at tracking and measuring their blood pressure on their own.

Sessions will be held in the W.R. Dulin Center on the campus of Scotland Memorial Hospital in the Community Health & Rehab building.

Dates are Aug. 24 and Aug. 31; Sept. 7 and Sept. 20; Oct. 5 and Oct. 18; and Nov. 14 and Nov. 21. The classes run from 10 to 11:30 a.m.

For information about the Know It, Control It for Seniors High Blood Pressure Management program by contacting Community Health Services at 910-291-6933.

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Blood pressure classes begin Thursday - Laurinburg Exchange

Health Matters: Living a Healthy Lifestyle – NBC2 News

With over a dozen triathlons under her belt, Erika Graziani, a dietitian with Lee Health, is now preparing for the International Triathlon World Championship.

Erikas daily routine consists of swimming, cycling, and running. If youre going to do triathlons training is really important.

Erika participated in her first triathlon in 2014 after coworkers at Lee Health convinced her to give it a try. With triathlons I didnt know what was going to happen with it. I thought Im going to have to try it and see and Ive really taken a liking to it.

With extensive training starting at 4 a.m., Erika stays disciplined to her exercise and nutrition. In my position as a dietitian, I try to promote health and good nutrition so I try to practice what I preach and be a good role model, said Erika.

Erika has become an example a healthy lifestyle focusing everyday on wellness, nutrition, and exercise. But her next goal is the biggest one yet. In a few days, shell participate in the International Triathlon World Championship. Its amazing sometimes when you think, wow I did that. I remember thinking how can people do those, but again its just that training, said Erika.

While her immediate goal is to cross the finish line, her ultimate goal is to inspire her patients and community to stay active. Knowing that youre going to feel good about it later pushes me, said Erika.

Staying active and healthy eating keeps her motivated to live a healthy lifestyle.

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Health Matters: Living a Healthy Lifestyle - NBC2 News

Healthy lifestyle: Butte woman powers ahead with workouts | Health … – Montana Standard

Go for a spin in fitness devotee Kelli Sullivans class and youll hop off the cycle inspired.

The operative word inspirational swirls around Sullivan, forever encouraging, prompting and demonstrating what it means to be in tip-top shape at any age while stressing the love for working out over any competitive bent that dogs other older, hard-core athletes.

She is a super inspiration for me, said nurse Janet Nothstine, of Butte, who takes Sullivans spin class twice a week at Fuel Fitness and who cycled from Kalispell to El Paso, Texas, in 19 days in 2008 when she turned 50.

Kellis so kind, Nothstine added. Shell stop and chat with someone in the weight room. She stays after when sometimes I do a few weights. If she sees something new thats interesting shes always looking at new things.

At 59, Sullivan the artist, mother and grandmother is in her third decade of lifting weights a few times a week.

Soon after her son Willy was born 28 years ago, she started lifting weights at the Butte Family YMCA. She hasnt let up.

A poster child for active women age 50 and over, Sullivan consistently finishes in the top half of her age group, including the Missoula Half-Marathon in 2016. Last year she also completed the Hibernian 5K St. Paddys Day Run in Anaconda and the Wulfmans Continental Divide Trail Race.

Sullivan is the first to tell you shes not competitive, but its apparent that the workout queen of Butte has been unswervingly competitive with herself to maintain a fitness level uncommon for women her age.

She runs or bicycles nearly daily and except for foot surgery last February has rarely taken time off from working out.

Ive done a ton of biking this summer, but I love to run, said the Butte resident who grew up with an athletic family and coach father in Great Falls. With running, you dont need equipment; you dont have to worry about that.

She loves running in the rain and she loves running on trails on the East Ridge.

Self-employed trainer Brian Yates knows Sullivan well and sings her praises. He has trained her up to three sessions per week when she was into running full marathons.

Shes absolutely unbelievable, said Yates, 45. She definitely made working out her lifestyle. Some people eat, sleep and breathe working out, but shes also an amazing mother and grandmother.

Hailing from an athletic family set Sullivan on a work-out course in junior high, when she started weekend runs with famed retired C.M. Russell High cross-country/track coach Branch Brady.

Thats when I got hooked on running, said Sullivan.

Her father, Don Cramer, coached CMR girls basketball, and sister, Connie Cramer Caouette is the city golf pro in Great Falls. Still, girls sports were limited during the mid-1970s when Sullivan was in school.

She has accomplished a lifetime of workouts, while also running her own art studio on Park Street for 16 years, creating old, archaic art and painting interiors on the side.

Shes an unbelievable artist, said Yates. She could pass for being in her late 40s and her whole life in general is unbelievable. She inspires a lot of people to make healthy living a lifestyle.

If youre starting to work out for the first time in your life, Sullivan gives practical advice:

Find something that you think is fun something you really like to do. Set realistic goals.

For example, start by walking 15 minutes a day, three times a week, then slowly increase your time and frequency.

Not everyone will like spinning on an indoor bike, but the beauty lies in its non-competitive aspect.

People of all levels can cycle, she said. We always start on a flat road, then you determine which level to start with. Youre challenging yourself.

The last outcome she wants is to dread workouts.

Im all about fun, she said.

As for using free weights or the high-tech machines available at Fuel Fitness, the YMCA and other gyms, Sullivan recommends hiring a trainer to learn safe, correct techniques.

At 5-foot-7, a taut 138 pounds and sporting a low heart rate, Sullivan turns 60 next May. Despite her recent big toe joint replacement and nagging foot arthritis, she has returned to running. She will not be slowed, especially since she loves the outdoors.

Ive got a little plan, Sullivan said slyly. When I cant run anymore, Ill hike.

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Healthy lifestyle: Butte woman powers ahead with workouts | Health ... - Montana Standard

5 tips to make your healthy lifestyle more affordable | WFTV – WFTV Orlando

by: Jessica Thiefels | Contributor to Clark.comUpdated: Aug 21, 2017 - 11:19 AM

Living a healthy life is not cheap. If youre paying for things like supplements, gym membership fees and organic groceries on a consistent basis, yourcash is very likely slipping through your fingers before you can even count it.

Making your healthy life more affordable may not be easy, but once the necessary habits are adopted, it will become second nature to you!

Use these tips to save money, stay fit, and feel good about your physical and financial health.

Gyms can be expensive, but there are ways to get more and spend less if you know what to look for.

Read more: How to get a gym membership for really cheap

On the other hand, you can skip the gym altogether and use the Internet as your personal trainer. There are a number of websites that offer high-quality workout videos from top-tier trainers, for free or cheap. Here are a few to check out:

Not all grocery stores are created equal. While you might love the one thats closest to you because its convenient, it may not be the best option for saving every week. A recent pricing analysis found that Aldi offered the most in average monthly savings (34.5%). Trader Joes, known for its deals and discounts, came in last, with 0% average monthly savings. Get more shopping insights from the full CouponBox grocery analysis here.

If you dont have an Aldi near you, do your own pricing test. Each week for the next month, buythe same groceries at four different stores shopping at a different one each week. Save your receipts and compare. Where did you spend the least? Maybe one store has a bulk section, great for stocking up on pantry items, while another is better for produce and fresh protein. Then modify your shopping routine accordingly!

Read more: 15 ways to save on groceries without digging for coupons

If you love your supplements, youre not alone. The supplements industry is currently worth $37 billion, so there is clearly no shortage of supplements available.

And with a little research, you canfind what you need at a price you love. Before paying out of pocket, see if your doctor can write you a prescription. If you can buy it from the pharmacy, you may be able to use your insurance, which could save a few dollars, depending on what you need.

Otherwise, Vitacost and Supplement Warehouse offer steep discounts on a variety of brands and types, and My Supplement Store is almost always offering free shipping for purchases over $50.

Note:Its important to make sure you do your research and even ask your doctor aboutany supplements you decide you take, as they could include ingredients that conflict with other medications youre currently taking.

Read more: Avoid supplements with these ingredients

This may sound boring and typical, but planning your meals helps you buy just what you need, rather than spending on food that will end up in the trash. For example, you could plan on doing rice, veggies and protein for dinner for the next week. There are many ways you can change this up from day to day, while relying on a few affordable basics:

Planning your meals in this way allows you to get the most for your money, without spending on food you dont need.

Read more: 9 perks that make a Costco membership totally worth it

Government food assistance, often called food stamps or SNAP (Supplemental Nutrition Assistance Program), is offered for a reason: sometimes we need a little help, and theres no shame in that. Many college students, for example, can qualify and get $60 $100+ in food money every month.

When I was in college, this was a lifesaver. I was able to get the healthy food I wanted, and now, with a well-paying job, I can afford it myself. The best part: Most who qualify receive a debit card, so when you check out at the cash register, no one has to know its not your regular bank card.

Living a healthy life can be affordable if you plan a little, look for the deals, and know where to shop. Youll be glad you took the time to do a pricing test and find the best online workout subscription when you see that youre saving every month.

Clark.com

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5 tips to make your healthy lifestyle more affordable | WFTV - WFTV Orlando

St. Rita’s health focus: Sleep tips to get your kids ready for a successful school year – Lima Ohio

Sometime back in July most parents were given a list of school supplies for the upcoming year. Specific descriptions of just the right paper, pencils, crayons and calculators were provided to get them ready to start a new school year. However, on that list they did not find one of the most essential supplies students of all ages need. They were not given the key to unlocking a vital component in the success of their childs school year. That being the key to preparing their child for a good nights sleep following a long summer of sleeping in and staying up late.

The American Academy of Sleep Medicine (AASM) offers a list of recommendations to assure a child gets the healthy sleep they need to learn, function and grow. The week or two before classes return is a good time to start getting your child back on track with their sleep.

Many schools in the area start early in the morning and that makes healthy sleep for a child a challenge. Dont wait until school starts to prepare for the change in bed time, the AASM recommends a gradual transition in the upcoming weeks. A sudden change could make it difficult for him or her to fall asleep. Instead, slowly start making the bedtime earlier; pushing it forward by 5 to 15 minutes each day and waking the child up earlier using the same incremental times. Kids aged seven to twelve need 10 to 11 hours of sleep, while older kids need 8 to 9 hours. Once a sleep schedule is determined, stick to it, dont use the weekend to catch up on sleep.

Establish a relaxing bedtime routine. Start quiet time 1 hour to 1.5 hours prior to bedtime to allow your child to unwind. Include activities like a bath, brushing teeth, bedtime stories for young children or reading time for older children. This is the time to limit television, video games, and other electronic distractions, especially in bed. The bright light emitted by the devices can signal to the body that it should be awake and alert.

In addition to removing nighttime technology from the bedroom, avoid food and drinks with caffeine. A good rule of thumb is to limit pop and caffeinated drinks after 3 p.m. These drinks in the evening can interrupt your childs natural sleep pattern, making it difficult to fall asleep. A heavy meal prior to bed can also make it difficult for your child to fall asleep.

Provide for your child a peaceful bedroom environment. Keep the room dark and a room temperature that is neither too hot nor too cold. Electronic distractions like televisions, computers, or video games should be removed from your childs room and set up in a different location.

Helping children realize that sleep is an essential part of a healthy lifestyle is important for their future, as poor sleep can increase the risk of physical health problems throughout their life. These include obesity, heart disease and diabetes. Be a role model, set a good example for your child. Establish your own regular sleep routine.

If a consistent sleep schedule and good sleep hygiene do not appear to help your child achieve healthy sleep, your child may be suffering from a chronic sleep problem. Talk to your childs doctor or see a sleep medicine physician who has specialized training and expertise to diagnosis and treat all forms of sleep illness.

The sooner your child readjusts to a school-time sleep-schedule, the better he or she will feel in the classroom putting to use their new school supplies.

ST. RITASHEALTH FOCUS

Lisa Taylor is a sleep technologist at Mercy HealthSt. Ritas Sleep Center.

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St. Rita's health focus: Sleep tips to get your kids ready for a successful school year - Lima Ohio

Time to work together on plans for a healthy lifestyle – TODAYonline

I read Prime Minister Lee Hsien Loongs National Rally Speech 2017 with interest.

Diabetes mellitus and the associated problem of being overweight are indeed huge health problems for Singaporeans.

Diabetes leads to many complications, which extend beyond the kidneys, heart, and brain.

Half to three-quarters of diabetic patients have fatty liver disease, which has become the most common liver problem in many countries, including Singapore and the United States.

Even in China, where Hepatitis B is prevalent at 10 per cent, the occurrence of fatty liver disease in the general population there is estimated to be 20 per cent.

Patients with the disease are at risk of liver cirrhosis, liver failure, and liver cancer. It is expected to be the major cause of liver problems in the next few decades.

Right now, there is no effective and safe medication for treating fatty liver disease.

Most of the clinical research on pharmacological agents that alter the course of fatty liver disease is still ongoing.

However, most studies have shown that weight loss and regular exercise are key, proven treatments for fatty liver disease. A loss of 5 per cent of ones body weight would lead to an improvement in liver function.

As PM Lee said, there is no single magic way to treat diabetes mellitus. Multiple angles of treatment are needed.

Encouraging people to have a healthy diet and do daily exercise for 30 to 60 minutes are the cornerstones of treating diabetes, as well as the associated problem of fatty liver disease.

It is time for all stakeholders including doctors, patients, food sellers, food manufacturers, and the associated government agencies such as the National Environment Agency and Active SG, as well as the Health Ministry to work together in laying out strategies to help people lead a healthy lifestyle.

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Time to work together on plans for a healthy lifestyle - TODAYonline

Erectile Dysfunction/Low T Men’s Health Georgia

Peyronies disease is an acquired inflammatory condition of the penis where a plaque (scar) develops under the skin of the penis leading to curvature, painful erections, and erectile dysfunction. The plaque consists of scar tissue that forms within the wall of the tissue called the tunica albuginea that surrounds the corpus cavernosum, which is the structure that fills with blood to create erections. When the plaque is large enough, it causes curvature of the penis that may be painful and may prevent intercourse. Also, the plaque may cause erections to be less rigid or difficult to maintain. Peyronies disease is common and may run in families, with an estimated 1% of all men having some degree of Peyronies disease.

The exact cause of Peyronies disease is unknown, but it is likely that a genetic predisposition to abnormal scar tissue formation is an underlying cause. In some men, Peyronies disease is caused by trauma to the penis, for example, sudden and painful bending during intercourse.. Peyronies disease can be associated with abnormal scar tissue formation in the plantar fascia of the foot (Ledderhoses disease), the eardrum (tympanosclerosis), or the palm of the hand (Dupuytrens contracture). Low testosterone, or hypogonadism, is also commonly seen in men with Peyronies disease, which may predispose to poor wound healing and inflammation.

Peyronies disease often begins with the sudden onset of curvature to the erect penis, which may be initially painful. Peyronies disease may present with the new onset of erectile dysfunction. You or your doctor may notice an abnormal hardening or calcification of the tissue below the skin along the shaft of your penis. The plaque commonly occurs on the upper side of the penis near the base, but can also form on the bottom or side of the penis. In some men, the plaque occurs around the entire penis. The condition is usually asymptomatic in the flaccid state.

During erection, there may be:

Ultrasound can be used to evaluate the size of the plaque, the degree of penile curvature and severity of associated erectile dysfunction. To perform this ultrasound study, medicine is injected into the penis to produce an erection (see attached). A painless ultrasound probe is used to determine the plaque volume, degree of curvature, arterial blood flow into the penis, and the ability of the veins to keep this blood from exiting the penis. This information is used to develop an individualized treatment plan.

A combination of oral medications and/or penile injections may improve the symptoms Peyronies Disease. A vacuum erection device (VED) may be beneficial to improve penile length or aid with erections if venous leak erectile dysfunction is detected on ultrasound. For a small percentage of men, the curvature can improve over time with or without treatment.

Oral Medications:

The following medications may alleviate some symptoms or slow the progression of Peyronies disease:

Penile Injections:

Injections of medication directly into the penile plaque are an option that may benefit some men. Traditional intralesional injection therapies include verapamil and interferon. Xiaflex, an intralesional injection therapy made from collagenase clostridium histolyticum, offers certain men a potential decrease in curvature and symptoms with a simple office procedure. Xiaflex is an option for men with stable Peyronies disease, intact erectile function, and a curvature between 30 and 90 degrees. Xiaflex consists of a series of one to four 2-day injection cycles in combination with modeling therapy (bending) by the clinician.

Surgical Repair:

Surgical treatment is typically reserved for men with a severe penile curvature or erectile dysfunction that prevents intercourse. The main goal of surgery is to straighten the penis enough to restore satisfactory sexual function.

Surgical procedures for men with severe curvature but preserved erection function may include:

Penile Prosthesis:

For men with Peyronies disease and erectile dysfunction not responsive to conservative treatment options, implantation of a penile prosthesis is the best option. A penile prosthesis completely cures the disorder by restoring sexual function, a straight penis, and ones confidence. Performed through a small hidden penoscrotal incision, a penile implant is invisible in your body while producing a completely natural erection and sexual experience. Sensation, orgasm, ejaculation, and urination are unaffected. The prosthesis has the highest success rate of all the treatments for Peyronies disease and erectile dysfunction, and over 90% of men and their partners have reported satisfaction after the procedure. There are two main types of penile prosthesis: inflatable and malleable. An inflatable penile prosthesis consists of 3 components that allows for a normal flaccid state, and then inflation through a scrotal pump produces a rigid state. A malleable penile prosthesis exists in a permanent semirigid state that bends downwards for dressing and bends upwards for sexual activity.

Videos:

Peyronies Disease Management Dot Plication Surgical Management

Circumferential Peyronies Plaque Excision with Semirigid Penile Implant

Peyronies Disease

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Erectile Dysfunction/Low T Men's Health Georgia

‘Bigfoot’ Silva responds to criticism of Rico Verhoeven fight, compares it to Mayweather vs. McGregor – MMA Fighting

Glory heavyweight champion Rico Verhoeven will return to the ring in a non-title bout on Oct. 14 in Gangzhou, China, taking on former UFC fighter Antonio Silva, but fans didnt seem to approve the match-up.

Bigfoot" was knocked out seven times over the past four years, winning only one of his last 10 MMA bouts, and never competed in a kickboxing fight before. Verhoeven, on the other hand, holds a 51-10-1 kickboxing record with wins over the likes of Badr Hari, Peter Aerts, Gokhan Saki and Sergei Kharitonov.

"Critics will always exist and we have to know how to deal with them, Silva told MMA Fighting. "Sometimes they dont even mean to criticize you, but they are just jealous they wanted to be a professional fighter and dont have that talent. I was always a humble person, I came from a humble family in Paraba and competed around the world, and some people dont accept that.

"Its a heavyweight fight and anything can happen. I respect Rico, he's the champion, but when I step into the ring anything can happen."

The criticism is not of Silva taking a fight against the champion, but toward the promotion for booking someone who has been knocked out many times recently against the best heavyweight kickboxer on the planet.

Asked if someone in his team was against the match-up for health reasons, Silva said it was quite the opposite.

"As soon as we received the offer, everyone was in favor of it, "Bigfoot" said. "My manager, Alex Davis, said it was a good fight because he knows me and knows I can go there and put on a good fight. Everyone supported me because the impossible doesnt exist. If you go in there thinking that you cant do it, that hes the No. 1, or if you go there for the money, you already lost. I dont think like that. Im not going there for money or media, Im going there because I know I can put on a good fight."

"I went five rounds with Mark Hunt, and we stood and fought for 22 minutes. I knocked out (Alistair) Overeem, a K-1 champion, he continued. "Every athlete has to be versatile. I started in karate, but I always trained everything. Not having to worry about getting taken down or being pressed against the cage makes the camp and the actual fight easier."

Silva started his camp three weeks ago, as soon as he was offered the fight, and is excited about the challenge.

"Its a new experience for me, he said. "Im a professional athlete for years and I like to try new things, new challenges. I feel like an amateur going for his first fight, trying to show what he can do, and God willing everything will be alright.

The Brazilian heavyweight started in martial arts in karate, training for 12 years until he turned 17 and decided to add jiu-jitsu to his game. Now, he says, I train muay thai and boxing four times a week."

For his kickboxing debut, Bigfoot" will move his camp to his hometown Brasilia, Brazil, to train with UFC veteran Guto Inocente, a second-degree kickboxing black belt who holds a 34-8 kickboxing record, 5-1 under the Glory banner. Silva also invited Pedro Rizzo to join his camp in Brasilia.

"Rico is the champion, he deserves a lot of respect, Silva said. "Hes the best heavyweight kickboxer in the world. Im an amateur, its my first kickboxing fight, and I want to show what I can do. I have nothing to prove, I have no responsibility. Rico has the responsibility, hes the champion. The pressure is on him. Im cool."

The 37-year-old heavyweight compares his Glory debut to Conor McGregors upcoming clash with boxing legend Floyd Mayweather, when the UFC lightweight champion steps into the boxing ring for the first time against a 49-0 professional boxer in Las Vegas.

"Its a similar situation, Silva said. "McGregor never boxed and is going there to try to surprise. He has no pressure over himself because 99 percent of the people bet on Mayweather. Hes undefeated, 49-0, so most of the people think he will win. Its the same thing in this fight. But were two human beings stepping into a ring to fight. Anything can happen in a heavyweight fight, one hand can land and change the story."

"Im rooting for McGregor, he added. "He deserves respect. Hes a two-division champion in the UFC and is making history. Him as a person, he talks a lot, I dont consider him an idol, but he deserves respect. Anything can happen in this fight. Im rooting for him even though I think Mayweather will win because hes 49-0 and always trained that, so its complicated. But everything is possible."

According to Silva, hes getting paid "much more" in his recent fights compared to his previous bouts in the UFC, but thats not the only difference in this fight. The Brazilian heavyweight, who was only allowed to use testosterone replacement therapy once in the UFC against Mark Hunt, when he ended up testing positive for elevate testosterone levels restarted the treatment before his last MMA fight.

"My case is not for muscular gain or to enhance performance, but for health issues, said Silva, who lost his last fight to former Bellator heavyweight champion Vitaly Minakov in Russia. "I really need this in my life to be physically and mentally well. Ive fought in the UFC when my testosterone levels were at 77 three weeks before the fight. That's the level of a 90-year-old man. My levels were always low, 300, when someone at my age would be 800. I have doctors following me, making sure my levels are always at the normal range.

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'Bigfoot' Silva responds to criticism of Rico Verhoeven fight, compares it to Mayweather vs. McGregor - MMA Fighting

Transhumanism Is Not Libertarian, It’s an Abomination – The American Conservative

Last week in TAC, Zoltan Istvan wrote about The Growing World of Libertarian Transhumanism linking the transhumanist movement with all of its featureslike cyborgs, human robots and designer babiesto the ideas of liberty. To say Mr. Istvan is mistaken in his assessment is an understatement. Transhumanism should be rejected by libertarians as an abomination of human evolution.

We begin with Mr. Istvans definition of transhumanism:

transhumanism is the international movement of using science and technology to radically change the human being and experience. Its primary goal is to deliver and embrace a utopian techno-optimistic worlda world that consists of biohackers, cyborgists, roboticists, life extension advocates, cryonicists, Singularitarians, and other science-devoted people.

The ultimate task, however, is nothing less than overcoming biological human death and to solve all humanitys problems. Throughout much of Mr. Istvans work on this issue, he seems to think these ideas are perfectly compatible with libertarianismself-evident evenso he doesnt care to elaborate for his befuddled readers.

While most advocates of liberty could be considered, as Matt Ridley coined it, rational optimistsmeaning that generally we are optimistic, but not dogmatic, about progressit is easy to get into a state in which everything that is produced by the market is good per se and every new technology is hailed as the next step on the path of progress. In this sense, these libertarians become what Rod Dreher has called Technological Men. For them, choice matters more than what is chosen. [The Technological Man] is not concerned with what he should desire; rather, he is preoccupied with how he can acquire or accomplish what he desires.

Transhumanists including Mr. Istvan are a case in point. In his TAC article he not only endorses such things as the defeat of death, but even robotic hearts, virtual reality sex, and telepathy via mind-reading headsets. Need more of his grand ideas? How about brain implants ectogenesis, artificial intelligence, exoskeleton suits, designer babies, gene editing tech? At no point he wonders if we should even strive for these technologies.

When he does acknowledge potential problems he has quick (and crazy) solutions at hand: For example, what would happen if people never die, while new ones are coming into the world in abundance? His solution to the fear of overpopulation: eugenics. It is here where we see how libertarian Mr. Istvan truly is. When his political philosophythe supposedly libertarian onecomes into conflict with his idea of transhumanism, he suddenly drops the former and argues in favor of state-controlled breeding (or, as he says, controlled breeding by non-profit organizations such as the WHO, which is, by the way, state financed). I cautiously endorse the idea of licensing parents, a process that would be little different than getting a drivers licence. Parents who pass a series of basic tests qualify and get the green light to get pregnant and raise children.

The most frustrating thing is how similar he sounds to communists and socialists in his arguments. In most articles you read by transhumanists, you can see the dream of human perfection. Mr. Istvan says so himself: Transhumanists want more guarantees than just death, consumerism, and offspring. Much More. They want to be better, smarter, strongerperhaps even perfect and immortal if science can make them that way.

Surely it is the goal of transhumanists that, in their world, the average human type will rise to the heights of an Aristotle, a Goethe, or a Marx. You can just edit the genes of the embryo in the way that they are as intelligent as Aristotle, as poetic as Goethe, and as musically talented as Mozart. There are two problems, though: First, the world would become extremely boring, consisting only of perfect human beings who are masters at everything (which perhaps would make human cooperation superfluous). Second, that quote was famously uttered by the socialist Leon Trotsky.

As Ludwig von Mises wrote sarcastically, the socialist paradise will be the kingdom of perfection, populated by completely happy supermen. This has always been the mantra of socialists, starting with utopian thinkers like Charles Fourier, but also being embraced by the scientific ones like Marx, who derived his notion of history in which communism is the final stage of humanity from Hegel. Hegel himself believed in the man-godnot in the way that God became man through Jesus, but that man could become God one day. Intentionally or not, transhumanists sound dangerously similar to that. What they would actually create would be the New Soviet Man through bio-engineering and total environmental control as the highest social goal. In other words, you get inhuman ideological tyranny taken to a whole new level.

It should be noted that sometimes transhumanists recognize this themselvesbut if they do, their solutions only make things worse (much worse). Take Adam Zaretsky as example, who says that these new human beings shouldnt be perfect: Its important to make versions of transgenic human anatomy that are not based on idealism. But his solution is frightening: The idea is that you take a gene, say for pig noses, or ostrich anuses, or aardvark tongue, and you paste that into a human sperm, a human egg, a human zygote. A baby starts to form. And: We could let it flow into our anatomy, and these peoplewho yes, are humansshould be appreciated for who and what they are, after they are forced to be born in a really radically strange way. Its no surprise that Rod Dreher calls Mr. Zaretsky a sick monster, because he truly seems to be one when it comes to his transhumanist vision. He wants to create handicapped human beings on purpose.

If this were what libertarians think should happen, it would be sad (thankfully its mostly not). As Jeff Deist notes, it is important to remember that liberty is natural and organic and comports with human action. It doesnt require a new man. Transhumanists may say that the introduction of their idea is inevitable (in Istvans words, Whether people like it or not, transhumanism has arrived) but that is not true. And in this sense, it is time for libertarians to argue against the notion of extreme transhumanism. Yes, the market has brought it about and yes, the state shouldnt prohibit it (though giving your baby a pig nose could certainly be a violation of rights), but still, one shouldnt be relativist or even nihilist about such frightening developments. It would be a shame if the libertarian maxim of Everyone should be able to do whatever one wants to (as long as no one is hurt by it) becomes Everyone should do whatever one can do just because it is possible.

Finally, it comes as no surprise that transhumanists are largely, if not all, atheists (or as Mr. Istvan says: Im an atheist, therefore Im a transhumanist. This just proves what the classical liberal historian Lord Acton talked about when he said, Progress, the religion of those who have none. In the end, transhumanism is the final step to get God out of the way. It would be the continuation of what Richard Weaver wrote about in Ideas Have Consequences: Instead of seeing nature, the world and life overall as a means to get to know God, humans in the last centuries have become accustomed to seeing the world as something that is only there for humans to take and use for their own pleasures. Transhumanism would be the final step of this process: the conquest of death.

You dont have to be religious to find this abhorrent. As we have seen, it would be the end to all religion, to human cooperation overall, in all likelihood to liberty itself, and even the good-bye to humanity. It would be the starting point of the ultimate dystopia.

Kai Weiss is an International Relations student and works for the Austrian Economics Center and Hayek Institute, two libertarianthink tanks based in Vienna, Austria.

Excerpt from:
Transhumanism Is Not Libertarian, It's an Abomination - The American Conservative

Bloodborne, Transhumanism and Cosmic Cyberpunk – Kotaku UK (blog)

With all its morbid decadence, the richly-layered Gothic imagination and cosmic horror of Bloodborne tends to overshadow some of its more (post)modern influences. Bloodborne isnt a traditionalist, after all, but a punk: or to be more precise, a cyberpunk. It may not havesinister corporations or hackers, yet this sci-fi renegade still conjures the rebellious ghost in the machine.

Most obviously, theres the overpowering presence of that looming megalopolis Yharnam as dependent on monumental, almost brutalist architecture as any good futuristic urban sprawl. The social dynamics within Yharnam echo the politics of cyberpunk, the hegemonic power of the Healing Church pitted against the social outcasts roaming the grimy streets. Dangerous social experiments and unchecked technological advancements have led to a Victorian dystopia. There are even cyberspaces, simulated, subordinate worlds in the form of the Dreams, which can be accessed and even hacked by those who are privy to secret knowledge.

Yharnham:

Ridley Scott'sBlade Runner:

And just like cyberpunk, the world of Bloodborne is held captive by the promise of transhumanism the idea that humankind will, one day, be able to transcend our fleshlylimitations and become something more. Whether it is Deus Ex or Bloodborne, the tool for this quasi-religious endeavour is cutting edge research and technology. In Deus Ex, that means body modification through nanotech or even merging consciousnesses with an omnipresent AI. In Bloodborne, its the Healing Church and Byrgenwerth researching into the old ones and their blood that drives this change: aiming to transform humans, in theory, into celestial beings that have entirely discarded their humanity. Not unlike in Blade Runner, the eye becomes an omnipresent symbol of self-directed evolution and the dangerous knowledge necessary to pursue it.

However, Bloodborneisa punk that refuses to slavishly follow in the tracks of those that came before. The differences are the most fascinating thing here. The futuristic vision of transhumanism, whether it is presented as a utopian promise or a dystopian threat, is seen as an evolutionary culmination or perhaps even singularity that severs the umbilical cord that connects us to our evolutionary history. The human is a product of natural processes, distant cousin of the apes. The posthuman the product of transhumanism is something different (strangely, it is our human arrogance that leads to this fallacy of teleological evolution.)

Blade Runner

Eye of a Blood-Drunk Hunter

Bloodbornes idea of transhumanism is recognisable, but different. Its still a morally complex idea, both pursued by individuals and institutions while also causing societal upheaval, but its vector is in the opposite direction. The path to transcendence doesnt lead the inhabitants of Yharnam away from humankinds evolutionary history, but confronts it head-on in a retrogressive journey. The first enemies our hunter encounters are beastmen, many of them recognisably human but some, like the werewolves or Vicar Amelia, almost devoid of human characteristics. Theyre hairy and canine, clearly mammalian despite their deformities. So far, this is in keeping with stories like Robert Louis Stevensons The Strange Case of Dr. Jekyll and Mr. Hyde or H.P. Lovecrafts tales of human degeneracy, such as Facts Concerning the Late Arthur Jermyn and His Family, in which a British nobleman burns himself alive after discovering that one of his ancestors was an ape goddess from the Congo. These stories play with our post-Darwinian revulsion at being the offspring of mere animals.

But as you progress through Bloodborne, the hunter descends deeper down the evolutionary ladder. Soon, enemies resemble snakes, insects, arachnids. Later, they become more alien still, strange variations of squids, snails, slugs (that is, molluscs) or even fungi. They have names like Celestial Emissary, or Celestial Child and are closely related to the Great Ones, some of whom, like Ebrietas or Kos, share similarities with the games mollusc-like creatures. Bloodborne displays a special fascination with mushrooms and molluscs, as well as the creatures of the ocean (especially in The Old Hunters DLC). These creatures are associated with the primordial, the early origins of life on earth, and their strange forms, both beautiful and disturbing, gives them a semblance of otherworldliness. And since they dont seem to belong to this world, perhaps they originally visited earth from unknown regions of the cosmos?

Kos

Ebrietas, Daughter of the Cosmos

Celestial Child

Nudibranch, Nembrotha Kubaryana. Photo by Nick Hobgood

Nudibranch, Nembrotha Cristata. Photo by Chriswan Sungkono.

Nudibranch, Tritoniopsis Elegans. Photo by Sean Murray.

From this anthropocentric perspective, becoming like these creatures means getting closer to the miraculous origins of life, when the earth and the cosmos had yet to be disentangled. The transhumanism of Bloodborne thus turns the usual teleological view of human evolution on its head; the forces of evolution, whether natural or self-directed, will not bring humans closer to the gods, but have instead distanced them from the celestial spring of life. To fulfil their atavistic yearning to return to the lap of the cosmos, the inhabitants of Yharnam must regress to earlier evolutionary stages. The horror and tragedy of turning into wolf-like beasts, therefore, isnt just due to a revulsion to our animal ancestors or the destruction they cause, but the knowledge that those beastmen didnt regress far enough. If only they hadnt gotten lost in this evolutionary valley, they could have emerged on the other side as transcendental beings, as kin not of the earth, but the cosmos. At least, thats one way of looking at the complex picture Bloodborne paints.

The transcended hunter as slug-like Great One in Bloodbornes true ending

The beautiful thing about this is that it doesnt just fly in the face of transhumanism as it is usually understood, but the most problematic aspects of Lovecrafts work, too. The ugly concept of degeneracy, with all its overt racism, was an integral part of Lovecrafts fictional worlds. The ancient and unambiguously evil powers of the Great Old Ones is tied to primitives and mongrels, marginalised humans seen as genetically impure and degraded. They are easily manipulated by the old gods and worship them in the hidden and remote corners of the earth.

In Bloodborne, the blame of Yharnams ruin is dramatically shifted. The hidden corners of worship arent foreign jungles or secluded villages, but the sacred spaces of a church that is the backbone and centre of a sprawling megalopolis; the mysteries of the Great Ones are still secret knowledge, but secrets of a powerful, manipulative elite (as you would expect in the conspiracy-filled worlds of cyberpunk stories). But while this elites endeavours clearly lead to a horrific dystopia, the moral issues of this regressive transhumanism stay ambiguous throughout. The degenerate beastmen are hapless, unfortunate victims rather than villains. The experiment of transcendence through reverse evolution seems doomed to fail, but it is not at all clear whether that goal is inherently misguided. After all, the Great Ones seem amoral rather than evil (not unlike the people of Yharnam), and the hunter is no stranger to the allure these celestial beings exert through their disturbing kind of beauty. Perhaps their apparent darkness stems purely from the human minds failing to comprehend their true nature? Either way, Lovecrafts ideas of degeneracy doesnt entirely fit into Bloodbornes world.

Being kin to both the Lovecraftian as well as cyberpunk, Bloodborne, too, is a kind of mongrel. But this impurity is precisely what enables it to distinguish itself and comment meaningfully on its ancestral genres. It reshapes its influences by letting disparate ideas collide and creates something fresh from the wreckage. Its not unique in its subversion of transhumanist idealism or Lovecraftian racist tropes, but the way it combines these separate issues in a seamless if ambiguous whole is entirely original.

Bloodborne is both a cyberpunk dystopia in which the end point of self-directed evolution is not a disembodied mind, but a slug or a squid, as well as a tale of cosmic horror where that dubious degeneracy stems not from shady outsiders or social outcasts, but squarely from within organised mainstream religion and science. It shares with cyberpunk an awareness and distaste for the unequal power dynamics in a world governed by the amoral ambitions of hegemonies, but, like Lovecraft, looks backwards to our distant origins rather than to the future. And soBloodborne transcends its influences, and challenges us on new planes of existence.

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Bloodborne, Transhumanism and Cosmic Cyberpunk - Kotaku UK (blog)

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Anti-Aging & Medical Spa | Beverly Hills Rejuvenation Center

Growth in Nanomedicine market-2017 trends, forecasts, analysis – satPRnews (press release)

The report firstly introduced the Nanomedicine basics: definitions, classifications, applications and industry chain overview; industry policies and plans; product specifications; manufacturing processes; cost structures and so on. Then it analyzed the worlds main region market conditions, including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc. In the end, the report introduced new project SWOT analysis, investment feasibility analysis, and investment return analysis.

Download sample pages of this report: http://www.kminsights.com/request-sample-1892

Nanomedicine is a branch of medicine that applies the knowledge and tools of nanotechnology to the prevention and treatment of disease. Nanomedicine involves the use of nanoscale materials, such as biocompatible nanoparticles and nanorobots, for diagnosis, delivery, sensing or actuation purposes in a living organism.

The ongoing market trends of Nanomedicine market and the key factors impacting the growth prospects are elucidated. With increase in the trend, the factors affecting the trend are mentioned with perfect reasons. Top manufactures, price, revenue, market share are explained to give a depth of idea on the competitive side.

Each and every segment type and their sub types are well elaborated to give a better idea about this market during the forecast period of 2017respectively.

Download sample pages of this report: http://www.kminsights.com/request-sample-1892

About Us:Key Market Insights is a stand-alone organization with a solid history of advancing and exchanging market research reports and logical surveys delivered by our numerous transnational accomplices, which incorporate both huge multinationals and littler, more expert concerns.

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Growth in Nanomedicine market-2017 trends, forecasts, analysis - satPRnews (press release)

Nanomedicine applications in the treatment of breast cancer: current state of the art – Dove Medical Press

Back to Browse Journals International Journal of Nanomedicine Volume 12

Di Wu, Mengjie Si, Hui-Yi Xue, Ho-Lun Wong

Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, PA, USA

Abstract: Breast cancer is the most common malignant disease in women worldwide, but the current drug therapy is far from optimal as indicated by the high death rate of breast cancer patients. Nanomedicine is a promising alternative for breast cancer treatment. Nanomedicine products such as Doxil and Abraxane have already been extensively used for breast cancer adjuvant therapy with favorable clinical outcomes. However, these products were originally designed for generic anticancer purpose and not specifically for breast cancer treatment. With better understanding of the molecular biology of breast cancer, a number of novel promising nanotherapeutic strategies and devices have been developed in recent years. In this review, we will first give an overview of the current breast cancer treatment and the updated status of nanomedicine use in clinical setting, then discuss the latest important trends in designing breast cancer nanomedicine, including passive and active cancer cell targeting, breast cancer stem cell targeting, tumor microenvironment-based nanotherapy and combination nanotherapy of drug-resistant breast cancer. Researchers may get insight from these strategies to design and develop nanomedicine that is more tailored for breast cancer to achieve further improvements in cancer specificity, antitumorigenic effect, antimetastasis effect and drug resistance reversal effect.Keywords: nanomedicine, breast cancer, targeted delivery, drug therapy, drug resistance, tumor microenvironment

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Nanomedicine applications in the treatment of breast cancer: current state of the art - Dove Medical Press

Low T Center returning to sponsor Sorenson – ESPN

Mooresville, NC (August 17, 2017) - 'Low T Center' is continuing their partnership with Reed Sorenson and Premium Motorsports as the team heads to Bristol Motor Speedway for this weekend's battle under the lights in the Monster Energy NASCARS Cup Series, 'Bass Pro Shops NRA Night Race'. Sorenson will be back in his familiar No.15 Chevrolet SS.

'Low T Center' is the leader of physician-led diagnosis and treatment of low testosterone with 50 locations nationwide and growing. Studies indicate testosterone deficiency has been linked to diabetes, metabolic syndrome, obesity, and high blood pressure. 'Low T Center' was designed so men can walk in, take a simple blood test, and know within 45 minutes if they are a candidate for Testosterone Replacement Therapy. Experience shows testosterone injections may lead to improved energy, strength, and libido, as well as decreases in body fat, irritability and depression. Most health insurance is accepted for treatment. Now with new locations in downtown Chicago,IL and Murfreesboro,TN.

To find your closest center and to learn more, go to https://lowtcenter.com.

--- Premium Motorsports ---

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Low T Center returning to sponsor Sorenson - ESPN

AbbVie Hit With $150 Million Loss in Low-T Cardiac Trial – Lexology (registration)

Jury finds drugmaker responsible for fraudulent misrepresentation

Payday

An Illinois jury handed plaintiffs $150 million in a case against AbbVie Inc. and Abbott Labs. Jesse Mitchell and his wife, Kimberly, an Oregon couple, sued the defendants after the companies testosterone replacement drug AndroGel allegedly caused Jesses severe heart problems. Mitchell claims that he decided to try AndroGel after seeing advertisements for the drug. Upon receiving a prescription from his doctor, he used it from 2008 until 2012, when his heart problems began.

Bellwether

The Mitchellscomplaint, filed in November 2014, is one of more than 7,000 brought by consumers alleging that widely marketed low-testosterone therapies led to harmful cardiac-related side effects. In 2014 the lawsuits, which include cases against Besins and Eli Lilly, were consolidated into a multi-district litigation (MDL) in the Northern District of Illinois. The Mitchells case against AbbVie is one of a handful of bellwether cases involving the drugmaker that have been identified by the court.

Common to the AbbVie cases is the accusation that the company engaged in misleading ads that preyed on the hopes and fears of middle-aged men. The advertisements included suspect tests for Low T, which lumped in the normal effects of aging with symptoms of actual low-testosterone disorders.

One Out of Three

The Mitchells specifically alleged that AbbVie failed to warn consumers of the dangers of using AndroGel and that the design of the drug was defective and unreasonably dangerous. They also accused AbbVie of negligence, fraud and negligent misrepresentation, seeking a variety of damages, injunctive relief and attorneys fees. At trial, their attorneys urged legal theories of strict liability, negligence and fraudulent misrepresentation.

The jury let AbbVie off the hook for the first two claims, failing to find that AbbVies conduct caused Mitchells medical woes. On the third count, the jury held the drugmaker liable for fraudulent misrepresentation related to the advertising campaigns launched by the company.

The Takeaway

Courts find bellwether cases to be a helpful tool for spotting and resolving certain issues common to a large number of lawsuits. The Mitchells case, along with the other low-testosterone bellwethers, will have an impact on the fate of the remaining litigation in the MDL.

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AbbVie Hit With $150 Million Loss in Low-T Cardiac Trial - Lexology (registration)

Testosterone therapy improves sexual functions – India New England

New York Long-term testosterone replacement therapy improves both sexual and urinary functions as well as quality of life for men suffering from a condition due to deficiency of the hormone, according to a study.

Testosterone is a steroid hormone involved in the regulation of sexual function, urinary health and metabolism as well as a number of other critical functions.

For most men, testosterone concentration declines slowly with age and may not cause immediate major symptoms.

However, some men may experience a host of signs and symptoms constituting a clinical condition called Testosterone Deficiency (TD), or male hypogonadism, which is attributed to insufficient levels of testosterone.

Office Portrait of MED Prof. Dr. Abdulmaged TraishPhoto by Vernon Doucette for Boston University Photography

As a result, they experience symptoms as varied as erectile dysfunction, low energy, fatigue, depressed mood and an increased risk of diabetes.

The study, published in the Journal of Urology, investigated the effects of long-term testosterone replacement therapy on urinary health and sexual function as well as quality of life in men with diagnosed, symptomatic testosterone deficiency.

More than 650 men in their 50s and 60s enrolled in the study, some with unexplained testosterone deficiency and others with known genetic and auto-immune causes for their hypogonadism.

It is thought that testosterone treatment in men may increase prostate size and worsen lower urinary tract symptoms, said Abdulmaged Traish, Professor of Urology at Boston University School of Medicine in the US.

However, the researchers discovered that despite increased prostate size in the group that received testosterone therapy, there were fewer urinary symptoms such as frequent urination, incomplete bladder emptying, weak urinary stream and waking up at night to urinate.

In addition to these subjective improvements, the researchers conducted objective testing that showed that those men treated with testosterone emptied their bladders more fully.

Finally, testosterone treatment also increased the scores patients received on assessments of their erectile/sexual health and general quality of life, the study said.

Related

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Testosterone therapy improves sexual functions - India New England