What Is Skinny Fat? – How to Tell If You’re Metabolically Obese – GoodHousekeeping.com

The notion that weight determines your health is seriously disturbed. As a Registered Dietitian, I know firsthand that calculations like body mass index (BMI) are completely outdated and are a poor measure of health since they only look at weight and height. Looking beyond weight is important to understand what is going on inside your body. Just because you have a normal BMI doesn't necessarily mean you are healthy: enter the term "skinny fat."

The term first gained traction after a piece in Time Magazine profiled individuals who had "normal weight" but had some major underlying health issues. Medically described as metabolically obese normal weight, this refers to people who may have a normal weight or BMI but have risks for health problems in the same way as an outwardly obese person would. Although we don't like the term "skinny fat" as it is super shame-y, it is commonly used describe a serious health issue.

Does your diet primarily consist of excessive sugar, salt, and processed foods? Was the last time you visited a gym back in freshman year of college? Poor diet and lack of exercise, as well as a sedentary lifestyle, can lead to metabolic obesity. Most of us have a decent idea of whether or not we eat a balanced diet and stay active on a consistent basis.

Some more clinical indicators of being metabolically obese that you can discuss with your doctor include:

Diet, exercise, and lifestyle factors all play a huge part in maintaining good health and promoting longevity. Even if you have a normal BMI, high cholesterol and elevated blood sugar can put you at increased risk of heart disease and diabetes. Research has shown that poor diet and lack of exercise are also two key factors that can increase a persons risk of developing cancer.

A big danger for individuals who are metabolically obese is excess visceral fat. While subcutaneous fat (also known as "belly fat") is the layer of fat that sits directly under the skin and can be easy to see, visceral fat lies deeper and surrounds the internal organs. Visceral fat has been strongly linked to metabolic disease and insulin resistance, even for individuals with a BMI within the normal range. You may have heard of the apples and pears scenario that mimics body composition: pears tend to store fat in their lower extremities such as the hips and thighs, whereas apples tend to store fat in the belly. Individuals with an apple shape that store fat in the belly tend to have more visceral fat. Your waist circumference can give you a clearer picture: men should have a waist circumference of less than 40 inches and women should have a waist circumference of less than 35 inches. Cortisol, which is the stress hormone, can also increase how much visceral fat your body stores.

Stay hydrated: Did you know that up to 60% of the human adult body is made up of water? If there is one thing you can do for your health, its to start committing to your hydration. Try lining up your water bottles on your desk so you can see how much you need to drink by the end of the day. When you have a goal and can visualize it, meeting your hydration needs may be easier. You can even fill up a pitcher and keep it in your fridge as a reminder that it must be finished by days end.

Focus on fiber: Fibrous foods like fruits, vegetables, and whole grains are loaded with vitamins and minerals. Plus, fiber can help lower cholesterol levels and also control blood sugar. Fruits and vegetables also are full of water and can help you meet your hydration goal without having to down another water bottle.

Get moving: How are you spending the majority of your day? Are you sitting at a desk or laying on the couch practically 24/7? A study published in 2019 by the European Society of Cardiology found that 20 years of a sedentary lifestyle is associated with a two times risk of premature death. Regular aerobic exercise can also reduce the amount of visceral fat in your body. Consider getting a standing desk at work or just making an effort to get up and move more throughout the day.

Commit to your sleep: Ongoing sleep deficiency is linked to increased risk for several chronic diseases, including heart disease and diabetes. Commit to going to bed an hour earlier and avoid skimping on sleep. Plus, the extra rest may give you more energy to workout the next day.

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What Is Skinny Fat? - How to Tell If You're Metabolically Obese - GoodHousekeeping.com

Working Monogamy – The Good Men Project

Is true, lasting monogamy a fading institution?

Ive worked with individuals, happily married couples, people on the dating scene, marriages on the rocks, new relationships, poly-amores, and everything in between.

I wouldnt say monogamous relationships are harder or easier to do really well than committed, consensually open relationships.

When Im working with a couple we aim to make their relationship fantastic. With this as the focus they stop thinking of monogamy as an issue either way. Seriously, people who are in a fantastic relationship arent coming to me to discuss their struggles with monogamy. (Or non-monogamy.) Its a non-issue.

That said, here is what we know about monogamy that works:

Working monogamy is monogamy in practice. Its not conceptual. Its not a personality type (as much as one might insist that it is). Monogamy is a relationship state. It means being monogamous to a real live human being, with all of their quirks and gifts and uniqueness.

What this means is, if youre currently in search of your ideal soul-mate, your perfect match on this EarthIf you left a partner who cheated on youIn short, if you are not in a relationshipThen I hate to break it to you: you are not monogamous.

You cant be monogamous without the who that you are monogamous to. What you are instead is what we might call monogamous to monogamy. You are monogamous to an idea. Its simply not the same as being monogamous to someone.

Why? Because it takes a lot to connect with another human being. All the more so, to connect in a way that eclipses all others.

If youre not actually in such a relationship if youre not doing what it takes to connect with someone at that level, grappling with the beautifully messy realities and complexities of human relating Im sorry but you have no claim to monogamy. There are plenty of people out there who are using their laundry list of ideals, monogamy among them, to avoid relationships rather than to get into one.

So get all up in there with someone. Then maybe we can have a meaningful conversation about monogamy.

Working monogamy is organic monogamy. Monogamy that arises spontaneously because the relationship really is that good. Where the thought of being with someone else draws a rather blank stare and a Why?

Organic monogamy is descriptive rather than prescriptive. It requires no effort and draws little attention. It isnt so much chosen or negotiated as discovered.

Monogamy is a convenient label for what youre naturally doing, left to your own devices. Just as the Moon travelling freely through space orbits the Earth. Theres no resisting temptation because there isnt anyone funner, sexier, more attractive, more alluring, or better in bed than the one youre with. There isnt any wandering because there isnt anywhere to go. Any step away is a step down from what youve already got.

I dont advocate monogamy as a principle, that its somehow intrinsically right or good or superior. I believe deeply in monogamy as a way that I have seen can work incredibly well, and I help couples have such a rich, fulfilling relationship that, if theyre choosing monogamy, its because its the natural best option for both of them.

Working monogamy is being monogamous to someone (as opposed to demanding monogamy from someone). It doesnt work that way. Monogamy has everything to do with your behavior and nothing to do with your partners.

Sure, you can extort / demand / insist on your partners monogamy. Perhaps indefinitely. But it will never get you a good relationship if you dont already have one.

I frequent a Facebook group for singles who are all followers of a certain very popular motivational speaker. Recently a woman posted that she met a great guy. She described his many wonderful qualities and how well-suited they were. But he refuses to be monogamous, and she was asking the group for thoughts on what to do. I read through the many responses, most of them some variation of telling her to dump the scoundrel and run as fast as she could, since hell never change. Until we got into a discussion of what she really wanted, what monogamy represented to her:

Exclusivity isnt the same as longevity. Exclusivity isnt the same as depth, or intimacy, or commitment. If your desire is to have a committed, long-lasting, passionate, deep, intimate relationship with someone, the only way is to build that kind of relationship with someone.

As for monogamy itself, the only kind of monogamy we really care about is the organic kind, where the relationship is so fantastic that nothing out there compares to what youve got at home. But that too has to be built. If you demand it, you end up with monogamy without longevity, without passion or intimacy or depth.

So having a monogamous relationship does not consist of finding a monogamous partner. Crappy relationships are the birthplace of all the affairs of the supposedly monogamy-minded. Newlyweds are generally not planning their future affairs.

By the same token, building a fantastic relationship can render open relationship status functionally irrelevant.

But in all my years of coaching/teaching and living, for that matter Ive never seen monogamy, in and of itself, make a crappy relationship fantastic.

Focusing on monogamy as an issue wont improve a relationship, but focusing on improving the relationship can neutralize monogamy as an issue.

Previously Published on Medium

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Working Monogamy - The Good Men Project

Human emotions must adapt to thrive in the machine age – TNW

Did you know TNW Conference has a track fully dedicated to bringing the biggest names in tech to showcase inspiring talks from those driving the future of technology this year?Tim Leberecht, who authored this piece, is one of the speakers.Check out the full Impact program here.

If there is pain, nurse it, and if there is a flame, dont snuff it out, dont be brutal with it. Withdrawal can be a terrible thing when it keeps us awake at night, and watching others forget us sooner than wed want to be forgotten is no better. We rip out so much of ourselves to be cured of things faster than we should that we go bankrupt by the age of 30 and have less to offer each time we start with someone new. But to feel nothing so as not to feel anything what a waste!

These are the words of theclosing monologue of the movieCall Me By Your Name(based on the namesake book by Andre Aciman); the monologue of the father, Mr. Perlman, who assures his son Ellio of the inconceivable magnitude of emotions, insisting that even the most conflicted ones are better than none.

These lines could not be more timely. We have begun to realize that feeling more not only makes for richer lives but is also the best antidote to a world of self-optimization and efficiency, in other worlds, a world of machines.

At the World Economic Forum in Davos this year, Alibaba co-founder and executive chairmanJack Mamade the case for investing in our emotional capacities and even proposed a love quotient. Management thinkers believe that socio-emotional skills are going to be a key asset in tomorrows marketplace, simply because tasks requiring operational excellence and efficiency are likely to be performed much more effectively by AI and robots. Emotions, however, remain a human bastion. Our very weakness is our strength.

In a 2016survey, the World Economic Forum ranked socio-emotional skills as increasingly critical for future career success. Business schools are adjusting their curricula to include them, and private educational institutions such asThe School of Lifehave made it their mission to teach them.

Read: [Humility, trust, and empathy: The skills needed to work with robots]

And yet, despite our most ambitious efforts to demystify them, emotions remain utterly mysterious and elusive. They are better felt than explained, better portrayed often through works of arts than analyzed. We dont understand them unless we feel them, and feeling them, of course, is the very blind spot that may prevent us from ever objectively understanding them.

There even appears to be some confusion as to what counts as human emotion and what does not, and which of our emotions are distinctive. For a considerable period of time, common wisdom held that there is a base set of six classic emotions: happy, surprised, afraid, disgusted, angry, and sad. But in 2014, a study by theInstitute of Neuroscience and Psychology at the University of Glasgowclaimed there are only four basic emotions happy, sad, afraid/surprised, and angry/disgusted. Ah, wouldnt life be easy and yet oh-so-boring if that were the case!?

However, in 2017, a new study by theProceedings of National Academy of Sciencessuggested that there are as many as 27 different categories of emotions, and that they in fact occur along a gradient and are not sharply distinguishable or mutually exclusive. This new set of emotions ranges from admiration, adoration, awe, and surprising outliers such as aesthetic appreciation, to envy, excitement, horror, and empathetic pain to equally unexpected contenders such as nostalgia, romance, or triumph.

Looking at this comprehensive list, a few emotions stand out. One wonders whether romance is an emotion or a feeling, an interpretation of an emotion, or simply a way to relate to the world. Similarly, the omission of loneliness is glaring, although in this case, too, one could argue that it is a feeling, not an emotion. Per neuroscientistDr. Sarah McKays definition, feelings aremental experiences of body states, which arise as the brain interprets emotions, themselves physical states arising from the bodys responses to external stimuli. Yet the line between the two remains blurry.

Moreover, some emotions may not have been listed because they areculturally unique, e.g.Schadenfreude, the very German joy over another persons mishap or misfortune. Or these Bantu, Taglog, and Dutch terms:mbuki-mvuki the irresistible urge to shuck off your clothes as you dance kilig the fluttering feeling as you talk to someone to whom you are attracted oruitwaaien the refreshing effects of taking a walk in the wind. Others that were included in the list such as triumphappear to be a temporary sign of our times more than a fixed emotion: in our winner-takes-all societies, winning is arguably the one emotion that is putting all the others in second place. The winner feels it all.

How will digital technology, specifically AI and robotics, affect our emotions?

Researchers have long studied our emotional relationship to machines. Numerousstudieshave proven that we quickly form emotional attachments to robots, and it might indeed be worthwhile exploring which social skills we need in order to collaborate with them.

So-called Artificial Emotional Intelligence (AEI), advanced by firms such asAffectiva,Emotient(acquired by Apple), andEmotion Research Lab, now seeks to analyze our emotions by scanning our facial expressions and body language. From studyingMark Zuckerbergs behavior during the congressional hearingsto the use for candidate assessments in job interviews (HireVue), AEI, like any technology, can be used for benevolent and malicious purposes, from boosting our emotional intelligence to manipulating and emotion-engineering us as citizens and consumers, from helping autistic children recognize their emotions (see, for example, theKaspar project) topenalizing us at the workplace for not being happy.

Empathetic robots occur at the timely convergence of two trends: empathy and AI. As we fear the loss of civility and with xenophobia, racism, and nationalism on the rise in many liberal societies, empathy has become a hot topic, and initiatives to muster it range from podcasts with those who are not like us or even bully us (e.g.Conversations with People Who Hate Me) toMITs Deep Empathyinitiative orGoogles Empathy Lab, to using VR and other immersive technologies as the great empathy machines.

At this yearsConsumer Electronics Showin Las Vegas, several robots were exhibited that can apply empathy and emotional intelligence toward their human user, e.g. the social robot Buddy; the table-tennis playing Forpheus that can read its opponents body language to anticipate their moves; or Pepper, which is capable of interpreting a smile, a frown, your tone of voice, as well as the lexical field you use and non-verbal language such as the angle of your head, according to its manufacturer, SoftBank. InJapan, a society with an aging population, empathetic robots like Paro, applied in elderly care, are becoming a mainstream phenomenon.

Analyst firmGartnerrecently predicted that by 2022 smart machines will understand our emotions better than our close friends and relatives, which of course is an outrageous claim, as the ethnographerJonathan Cookhas pointed out: The more certain research firms claim to be in their ability to measure emotion with quantitative precision, the more incompetent they are likely to actually be at accomplishing the task because they have lost touch with what emotion actually is, he writes.

And yet, the question remains: If robots become better at reading and responding to our human emotions, could technological advances in AI and robotics lead to the emergence of new emotions that were not only previously unmeasured, unnamed, and unidentified, but also un-felt?

You could argue that all possible human emotions have always been present and that we just lacked the words to describe them and only over time simply refined our understanding of them. But there are good arguments for accepting the notion of a history of emotions, the belief that emotions, like our bodies and cognitive abilities, have evolved over time as well, in response to everchanging environments and social stimuli.

Piotr Winkielman and Kent Berridge, psychologists at the UC San Diego and the University of Michigan, conducted an experiment in 2014 in which they showed participants sad and happy faces in such fast order that these had no conscious awareness of seeing any faces at all. When participants were asked afterward to drink a new lemon-lime beverage, those who had subliminally been exposed to the happy faces rated the drink better and also drank more of it than the others. The researchers took this as evidence to suggest the existence of unconscious emotions: feelings we have without actually feeling them. Evolutionarily speaking, the ability to have conscious feelings is probably a late achievement, they concluded. In other words, asentimental education, the education of our hearts, may indeed have been an accomplishment of civilization, a blessing and curse of modern man alike.

Aside from our consciousness of emotions, evolution may have caused new emotions to form. Take envy, and specifically status envy, as a more recent phenomenon, as a product of the industrial revolution and growing consumerism in developed countries. Envy necessitates a materialistic culture. Envy, if you will, is the refined, commoditized version of jealousy. It describes the disappointment and humiliated self that doesnt possess or receive what another one does, a self that finds itself excluded from the marketplace and not able to participate in the transaction.

The natural companion to envy in todays experience economy isFOMO the Fear-Of- Missing-Out. This fear is about missing out onexperience: it is a preemptive fear of loss as much as it is an envy for anothers, possibly richer and more rewarding experience. Ultimately, FOMO is a fear of dying dying without having lived.

While FOMO is its perverse version, boredom is the realhorror vacui. At first glance, it seems like an increasingly precious good. In fact, boredom might become extinct because of the proliferation of smart phones and other devices that deprive us of any vacant moment in time. However, due to automation and the loss of traditional employment, many of us will face more unstructured time in the future and will need help to combat the numbness of boredom as it engulfs our lives.

At the TED conference this year, science writerJessa Gambleheld a fascinating workshop on awe, an emotion triggered, by say, entering the St. Peters Basilica or experiencing the vastness of a desert.

Gamble referenced Stanford researcherMelanie Ruddwho studied the effects of awe on consumer behavior and claims that after feeling awe we tend to choose experiential goods like a movie over material goods like clothes. She further concludes that it also makes us more willing to volunteer in our communities. It looks like we need not only citizenship classes but also experiences of awe to build more civil societies.It is important though to note that awe empowers and disempowers at once. It makes us bigger and smaller. Gamble pointed out that the smaller self was both a prerequisite and consequence of awe: awe overpowers the self. That is both inspiring and humbling.

This very sentiment is at work in our relationship to AI and robots: we are in awe of them, which means, we are enamored and terrified at the same time. The uncanny valley a term used to describe the creepiness of an AI that is nearly fully artificial nor fully flesh, that is arrested at the blurry border between robotic and human, just humanoid enough to trigger our perception of human derangement will be our constant state for the foreseeable future.

It is this tension, this kind of contradictory feeling, that might serve as a blueprint for the future of emotions. The range of what we feel may increase, and it will be less and less binary. Even our language will have to catch up and come up with neologisms expressing this ambivalence. As always, the Germans are especially skilled at inventing new verbs, just consider Verschlimmbessern (which, loosely translated, means making something significantly worse by trying to make it incrementally better).

On the one hand, we are witnessing a radicalization of our emotions, as they are fleeing to the extreme edges (most of us will nod their heads in response to a book title like Pankaj Mishras The Age of Anger); on the other hand, our emotions are becoming more mixed, more conflicted, with different kinds of emotions overlaying each other.

At the same time, the volatility and complexity of our digital times are popularizing emotional states that are simple and balanced, such as mindfulness or the Japanese concept ofikigaithat is attracting more and more followers in the Western world. The Japanese island of Okinawa, whereikigaihas its origins, is said to be home to the largest population of centenarians in the world, and one of the allures of ikigai is the promise of longevity.Ikigaiis the convergence of four primary elements: What you love (your passion), what the world needs (your mission), what you are good at (your vocation), and what you can get paid for (your profession).

Ikigai is similar to the Western concept of purpose that has emerged as the holy grail of organizational and personal transformation. Whats your purpose? as a brand, company, individual, and even nation is the biggest and yet the smallest question everybody is happy to ask and only rarely really able to answer, despite an army of consultants and agencies devoted to it. It is not an entirely new concept. The American philosopher and civil rights leader Howard W. Thurman put it best: Ask what makes you come alive, and go do it. Because what the world needs is people who have come alive.

Mindfulness, ikigai, or purpose are neither emotions nor feelings they are techniques to help us restore balance as our emotions become more extreme and tools to help us refine how we manage them.

Naturally, emotions, too, are affected by the digitization, the atomization of our lives. In our fast-paced daily interactions, micro-aggressions the subtle humiliation by a cranky waiter can sour our mood as much as moments of micro-attachment the smile of a stranger on the subway can make our day. It appears that were transitioning from one emotional state to another much more quickly (the psychologist Susan David has coined the term emotional agility to pinpoint a new skill we must develop to cope with this phenomenon), that were losing the middle ground, the common thread, as well as the stability and continuity of long-term relationships. Instead, we are satisfying our emotional needs either through the instant kicks of the dopamine economy online, little escapisms (social media, gaming, movies, travel), or big ones: assuming an alternate identity, an avatar, a fluid self.

This virtualization of our selves may ultimately lead to the virtualization of our emotions, too, with us going from experiencing age-old emotions in new virtual environments to experiencing new emotions in digital or at least partly digital interactions, to full-on surrogate emotions, digital placeholders of the real thing: fake intimacy, virtual grief, and so on.

Japanese roboticist Hiroshi Ishiguro, who builds humanoid robots and was recently portrayed in this rivetingWired story,is convinced that human emotions are nothing more than responses to external stimuli. David Levy, in his seminal 2007 book,Love and Sex With Robots, subscribes to this point of view: If a robot behaves as though it has feelings, can we reasonably argue that it does not? He argues that human emotions are no less programmed than those of an AI: We have hormones, we have neurons, and we are wired in a way that creates our emotions. Levy projects that roughly by the year 2050 humans will want robots as friends, sexual partners, and even spouses.

This raises some big questions: Will it matter if our human emotions are increasingly manipulated by smart algorithms or even un-real, or does it suffice that wefeelthem? Have emotions ever been pure and can they? Arguably, weve never had much control over them. Emotions are never fully ours rather, despite our insisting on their private nature, theyre part of the public commons and some sort of open-sourced software. And yet, so much of what we feel we are incapable of sharing. We seem to lack the full code for unlocking it, which causes great frustration and a great desire to overcome it. Perhaps, in the future, hacking our brains may involve hacking our emotions, too. Technology may allow us to (re-)mix our emotions together with those of others, as the ultimate form of deep connection.

What makes us human is our proclivity to fall for the other: somebody who is not us, something beyond our control, greater than ourselves. We cant help but be drawn to persons, objects, or experiences that promise us new emotions, new sensations, new highs and lows, new joy and happiness, but also new heartbreak and suffering.

Although we are calling them by our name (Alexa, Buddy, Sophia, Kaspar, Samantha, Erica.), as a mirror of ourselves, the AI bots remain elusive. They are the enigmatic other, the greatest desire of all, the ultimate romance. If they can help us feelmoreand feel new emotions, and if we refine these emotions through more advanced emotional intelligence, with the arts and humanities as our interpreters, then the very machines that are growing adept at analyzing and manipulating how we feel will ensure that we stay a step ahead of them.

This article was originally published by Tim Leberecht, an author, entrepreneur, and the co-founder and co-CEO of The Business Romantic Society, a firm that helps organizations and individuals create transformative visions, stories, and experiences. Leberecht is also the co-founder and curator of the House of Beautiful Business, a global think tank and community with an annual gathering in Lisbon that brings together leaders and changemakers with the mission to humanize business in an age of machines.

Read next: The sustainability of wearables will depend on how we use them

Read more from the original source:
Human emotions must adapt to thrive in the machine age - TNW

(2020-2025) Vitamin Market Industry Trends, Growth, Size, Share, Industry Revenue, Future And Business Analysis By Forecast 2025|DSM, Lonza, CSPC…

QY ResearchAnalysts have used latest primary and secondary research methodologies to prepare this highly detailed and accurate report. The research study offers company profiling of leading players operating in theGlobal Vitamin Market 2020. Players profiled in the report are studied on the basis of recent developments, business strategies, financial progress, and main business.

Top Key Players Mentioned in this Report: DSM, Lonza, CSPC Pharmaceutical Group, BASF, Zhejiang Medicine, Shandong Luwei Pharmaceutical, Northeast Pharmaceutical, North China Pharmaceutical, NHU, Jubilant Life Sciences, Vertellus, Brother Enterprises, Adisseo, Zhejiang Garden Biochemical, Kingdomway

Los Angeles, United State, Feb 2020-The report offers a complete research study of the Global Vitamin Market that includes accurate forecasts and analysis at global, regional, and country levels. It provides a comprehensive view of the global Vitamin market and detailed value chain analysis to help players to closely understand important changes in business activities observed across the industry. It also offers a deep segmental analysis of the global Vitamin market where key product and application segments are shed light upon. Readers are provided with actual market figures related to the size of the global Vitamin market in terms of value and volume for the forecast period 2020-2025.

Click Below! For Vitamin Research Report

Major Manufactures Covered in this report:

DSM, Lonza, CSPC Pharmaceutical Group, BASF, Zhejiang Medicine, Shandong Luwei Pharmaceutical, Northeast Pharmaceutical, North China Pharmaceutical, NHU, Jubilant Life Sciences, Vertellus, Brother Enterprises, Adisseo, Zhejiang Garden Biochemical, Kingdomway

Market Segment by Type

Vitamin A, Vitamin B3, Vitamin B5, Vitamin D3, Vitamin E, Vitamin C, Others

Market Segment by Application

Feed Additives, Pharmaceuticals and Cosmetics, Food and Beverage

Global Vitamin Market: Regional Segmentation

For a deeper understanding, the research report includes geographical segmentation of the global Vitamin market. It provides an evaluation of the volatility of the political scenarios and amends likely to be made to the regulatory structures. This assessment gives an accurate analysis of the regional-wise growth of the global Vitamin market.

Regions Covered in the Global Vitamin Market:

The Middle East and Africa (GCC Countries and Egypt) North America (the United States, Mexico, and Canada) South America (Brazil etc.) Europe (Turkey, Germany, Russia UK, Italy, France, etc.) Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

Get Customized Report in your Inbox within 24 [emailprotected]https://www.qyresearch.com/customize-request/form/965258/global-vitamin-industry-depth-survey-report-2019

Key Areas of Focus

Important Questions Answered in this Report:-

Table of Contents

Executive Summary1 Vitamin Market Overview1.1 Product Overview and Scope of Vitamin1.2 Vitamin Segment by Type1.2.1 Global Vitamin Production Growth Rate Comparison by Type (2014-2025)1.2.2 Vitamin A1.2.3 Vitamin B31.2.4 Vitamin B51.2.5 Vitamin D31.2.6 Vitamin E1.2.7 Vitamin C1.2.8 Others1.3 Vitamin Segment by Application1.3.1 Vitamin Consumption Comparison by Application (2014-2025)1.3.2 Feed Additives1.3.3 Pharmaceuticals and Cosmetics1.3.4 Food and Beverage1.3 Global Vitamin Market by Region1.3.1 Global Vitamin Market Size Region1.3.2 North America Status and Prospect (2014-2025)1.3.3 Europe Status and Prospect (2014-2025)1.3.4 China Status and Prospect (2014-2025)1.3.5 Japan Status and Prospect (2014-2025)1.3.6 Southeast Asia Status and Prospect (2014-2025)1.3.7 India Status and Prospect (2014-2025)1.4 Global Vitamin Market Size1.4.1 Global Vitamin Revenue (2014-2025)1.4.2 Global Vitamin Production (2014-2025)

2 Global Vitamin Market Competition by Manufacturers2.1 Global Vitamin Production Market Share by Manufacturers (2014-2019)2.2 Global Vitamin Revenue Share by Manufacturers (2014-2019)2.3 Global Vitamin Average Price by Manufacturers (2014-2019)2.4 Manufacturers Vitamin Production Sites, Area Served, Product Types2.5 Vitamin Market Competitive Situation and Trends2.5.1 Vitamin Market Concentration Rate2.5.2 Vitamin Market Share of Top 3 and Top 5 Manufacturers2.5.3 Mergers & Acquisitions, Expansion

3 Global Vitamin Production Market Share by Regions3.1 Global Vitamin Production Market Share by Regions3.2 Global Vitamin Revenue Market Share by Regions (2014-2019)3.3 Global Vitamin Production, Revenue, Price and Gross Margin (2014-2019)3.4 North America Vitamin Production3.4.1 North America Vitamin Production Growth Rate (2014-2019)3.4.2 North America Vitamin Production, Revenue, Price and Gross Margin (2014-2019)3.5 Europe Vitamin Production3.5.1 Europe Vitamin Production Growth Rate (2014-2019)3.5.2 Europe Vitamin Production, Revenue, Price and Gross Margin (2014-2019)3.6 China Vitamin Production (2014-2019)3.6.1 China Vitamin Production Growth Rate (2014-2019)3.6.2 China Vitamin Production, Revenue, Price and Gross Margin (2014-2019)3.7 Japan Vitamin Production (2014-2019)3.7.1 Japan Vitamin Production Growth Rate (2014-2019)3.7.2 Japan Vitamin Production, Revenue, Price and Gross Margin (2014-2019)

4 Global Vitamin Consumption by Regions4.1 Global Vitamin Consumption by Regions4.2 North America Vitamin Consumption (2014-2019)4.3 Europe Vitamin Consumption (2014-2019)4.4 China Vitamin Consumption (2014-2019)4.5 Japan Vitamin Consumption (2014-2019)

5 Global Vitamin Production, Revenue, Price Trend by Type5.1 Global Vitamin Production Market Share by Type (2014-2019)5.2 Global Vitamin Revenue Market Share by Type (2014-2019)5.3 Global Vitamin Price by Type (2014-2019)5.4 Global Vitamin Production Growth by Type (2014-2019)

6 Global Vitamin Market Analysis by Applications6.1 Global Vitamin Consumption Market Share by Application (2014-2019)6.2 Global Vitamin Consumption Growth Rate by Application (2014-2019)

7 Company Profiles and Key Figures in Vitamin Business7.1 DSM7.1.1 DSM Vitamin Production Sites and Area Served7.1.2 Vitamin Product Introduction, Application and Specification7.1.3 DSM Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.1.4 Main Business and Markets Served7.2 Lonza7.2.1 Lonza Vitamin Production Sites and Area Served7.2.2 Vitamin Product Introduction, Application and Specification7.2.3 Lonza Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.2.4 Main Business and Markets Served7.3 CSPC Pharmaceutical Group7.3.1 CSPC Pharmaceutical Group Vitamin Production Sites and Area Served7.3.2 Vitamin Product Introduction, Application and Specification7.3.3 CSPC Pharmaceutical Group Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.3.4 Main Business and Markets Served7.4 BASF7.4.1 BASF Vitamin Production Sites and Area Served7.4.2 Vitamin Product Introduction, Application and Specification7.4.3 BASF Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.4.4 Main Business and Markets Served7.5 Zhejiang Medicine7.5.1 Zhejiang Medicine Vitamin Production Sites and Area Served7.5.2 Vitamin Product Introduction, Application and Specification7.5.3 Zhejiang Medicine Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.5.4 Main Business and Markets Served7.6 Shandong Luwei Pharmaceutical7.6.1 Shandong Luwei Pharmaceutical Vitamin Production Sites and Area Served7.6.2 Vitamin Product Introduction, Application and Specification7.6.3 Shandong Luwei Pharmaceutical Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.6.4 Main Business and Markets Served7.7 Northeast Pharmaceutical7.7.1 Northeast Pharmaceutical Vitamin Production Sites and Area Served7.7.2 Vitamin Product Introduction, Application and Specification7.7.3 Northeast Pharmaceutical Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.7.4 Main Business and Markets Served7.8 North China Pharmaceutical7.8.1 North China Pharmaceutical Vitamin Production Sites and Area Served7.8.2 Vitamin Product Introduction, Application and Specification7.8.3 North China Pharmaceutical Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.8.4 Main Business and Markets Served7.9 NHU7.9.1 NHU Vitamin Production Sites and Area Served7.9.2 Vitamin Product Introduction, Application and Specification7.9.3 NHU Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.9.4 Main Business and Markets Served7.10 Jubilant Life Sciences7.10.1 Jubilant Life Sciences Vitamin Production Sites and Area Served7.10.2 Vitamin Product Introduction, Application and Specification7.10.3 Jubilant Life Sciences Vitamin Production, Revenue, Price and Gross Margin (2014-2019)7.10.4 Main Business and Markets Served7.11 Vertellus7.12 Brother Enterprises7.13 Adisseo7.14 Zhejiang Garden Biochemical7.15 Kingdomway

8 Vitamin Manufacturing Cost Analysis8.1 Vitamin Key Raw Materials Analysis8.1.1 Key Raw Materials8.1.2 Price Trend of Key Raw Materials8.1.3 Key Suppliers of Raw Materials8.2 Proportion of Manufacturing Cost Structure8.3 Manufacturing Process Analysis of Vitamin8.4 Vitamin Industrial Chain Analysis

9 Marketing Channel, Distributors and Customers9.1 Marketing Channel9.1.1 Direct Marketing9.1.2 Indirect Marketing9.2 Vitamin Distributors List9.3 Vitamin Customers

10 Market Dynamics10.1 Market Trends10.2 Opportunities10.3 Market Drivers10.4 Challenges10.5 Influence Factors

11 Global Vitamin Market Forecast11.1 Global Vitamin Production, Revenue Forecast11.1.1 Global Vitamin Production Growth Rate Forecast (2019-2025)11.1.2 Global Vitamin Revenue and Growth Rate Forecast (2019-2025)11.1.3 Global Vitamin Price and Trend Forecast (2019-2025)11.2 Global Vitamin Production Forecast by Regions (2019-2025)11.2.1 North America Vitamin Production, Revenue Forecast (2019-2025)11.2.2 Europe Vitamin Production, Revenue Forecast (2019-2025)11.2.3 China Vitamin Production, Revenue Forecast (2019-2025)11.2.4 Japan Vitamin Production, Revenue Forecast (2019-2025)11.3 Global Vitamin Consumption Forecast by Regions (2019-2025)11.3.1 North America Vitamin Consumption Forecast (2019-2025)11.3.2 Europe Vitamin Consumption Forecast (2019-2025)11.3.3 China Vitamin Consumption Forecast (2019-2025)11.3.4 Japan Vitamin Consumption Forecast (2019-2025)11.4 Global Vitamin Production, Revenue and Price Forecast by Type (2019-2025)11.5 Global Vitamin Consumption Forecast by Application (2019-2025)

12 Research Findings and Conclusion

13 Methodology and Data Source13.1 Methodology/Research Approach13.1.1 Research Programs/Design13.1.2 Market Size Estimation13.1.3 Market Breakdown and Data Triangulation13.2 Data Source13.2.1 Secondary Sources13.2.2 Primary Sources13.3 Author List13.4 Disclaimer

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(2020-2025) Vitamin Market Industry Trends, Growth, Size, Share, Industry Revenue, Future And Business Analysis By Forecast 2025|DSM, Lonza, CSPC...

Americans say this popular diet is effective and inexpensive – YouGov US

Many Americans aim to eat a healthy diet, and some might be hoping to lose a few pounds. But which diets are Americans sticking to, and which ones are actually helping them lose weight?

A YouGov poll of more than 1,200 US adults finds that a majority of Americans have changed their diet at some point in order to lose weight (56%) or improve their physical health (54%).

Intermittent fasting, a diet where you only eat during certain times of day, is one of the most popular: 24 percent of US adults say theyve tried this diet for weight loss. An equal number say theyve tried the Atkins diet, which emphasizes foods that are low-carb.

About one in five have tried Weight Watchers (21%), the keto diet (19%) and the Mediterranean diet (18%).

But which diets do Americans say have been effective in helping them lose weight?

YouGovs data finds that majorities of people who have used these diets for weight loss find them to be effective.

Almost nine in 10 (87%) people who have tried intermittent fasting to lose weight say that this diet was very effective (50%) or somewhat effective (37%) in helping them lose weight. A similar number of people who have used Weight Watchers (86%) or the keto diet (85%) say these diets were effective for weight loss.

Majorities who have used Atkins (83%), the Mediterranean diet (81%), or vegetarianism (78%) for weight loss also say that these diets were effective in helping them to lose weight.

The diet Americans say is the best weight-loss diet may also be the most affordable one.

Intermittent fasting, which 87 percent of users say was effective for weight loss, is also seen as more inexpensive (80%) than expensive (18%), according to people who have tried it.

That isnt the case for many of the other diets YouGov asked Americans about. Majorities of users are more likely to see Weight Watchers, keto, Atkins and the Mediterranean diet as more expensive rather than inexpensive. Those who have adopted a vegetarian diet for weight loss are close to evenly split: 49 percent say it is expensive, 46 percent say it is inexpensive.

But in spite of the fact that many of these diets seem to be effective according to the people who have tried them, they remain largely unappealing to the American public.

A majority (58%) of US adults say that the vegetarian diet is somewhat or very unappealing. A plurality say the same when asked about the keto diet (47% find it unappealing), Atkins (47%), intermittent fasting (47%), or Weight Watchers (47%).

The only diet of this grouping that was seen as more appealing than unappealing was the Mediterranean diet. Over half (55%) say this diet is somewhat or very appealing; 31 percent say it is unappealing.

See the full survey results and sign up to be a part of the YouGov panel.

Related: One in five Millennials has changed their diet to reduce their impact on the planet

Methodology: Total unweighted sample size was 1,241 US adults, which included 137 who have used the keto diet for weight loss, 165 who have used the Atkins diet for weight loss, 172 who have used intermittent fasting for weight loss, 120 who have used the Mediterranean diet for weight loss, 146 who have used Weight Watchers for weight loss, and 95 who have used vegetarianism for weight loss. The figures have been weighted and are representative of all US adults (ages 18+). Interviews were conducted online between January 3 - 6, 2020.

Image: Getty

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Americans say this popular diet is effective and inexpensive - YouGov US

Balancing health with your culture – The Miami Hurricane

The 2010s saw a dramatic spike in new health trends. Specifically, more people turned to veganism and vegetarianism as a lifestyle. The biggest food prediction for this new decade is a plant-based revolution that will take the mainstream media by storm. Its no secret that eating less meat can be beneficial for your health while also helping the environment. However, with these popular food trends, it can be tricky to also honor ones culture. Cuisine is a major part of every culture and it is challenging to try new things while also staying true to your roots.

Since I was a kid Ive always been interested in plant-based food options and I would constantly drag my mom and sister to the quaint vegan cafes that began popping up throughout Miami. I think its important to try new things, especially when they can improve your health and expand your knowledge on the positive impacts eating the right foods can make. Exploring these vegan or vegetarian food trends is especially difficult when your cultures cuisine is very meat-centric. I come from a Cuban background and one of our main dishes is a bistec de palomilla, or butter-fried beef steak, usually paired with a side of rice and beans. As a person who hasnt had any type of steak in over three years, I can leave people confused.

Youre Cuban but you dont eat meat? is a question I hear a lot, but I think its important to separate heritage and culture from health choices because culture can be honored and celebrated in other ways besides food.

My best friend who is also Cuban can relate to this issue, having been a committed vegetarian for almost four years. In Cuban culture, Christmas Eve, or Noche Buena, is a big deal for us. The designated dish for this celebration is lechon, or pork, but for a vegetarian spending Christmas Eve with a Cuban family, it can be difficult to balance this tradition with personal choices.

I think the best way to navigate these situations is to remember that food is not tied to your identity, and although it may feel like food is the center of your culture, you can still express your heritage through alternate ways, including music, dress, meat-free food options and other customs that dont compromise the health-conscious decisions you want to abide by.

While I havent cut out meat from my diet entirely, I feel that cutting out red meat was the right choice for me and it has helped me feel better physically. I no longer feel sluggish after eating like I used to when I had massive cheeseburgers every other week. Now I opt for a turkey or veggie burger, and when Im really craving meat, Ill order an Impossible Burger, which is entirely plant-based but tastes and even looks like the real deal.

The vegan phenomenon is often criticized because it makes people feel outcasted if they still eat meat, but I think thats the wrong angle to take. I think it all comes down to respecting peoples personal choices, whether that means having meat regularly or leaning towards a more plant-based life. And these choices dont define how strong your pride is for your culture, because it is definitely possible to strike a balance between the traditions of the past and the new ideas of the present.

Nicole Macias is a senior majoring in English.

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Balancing health with your culture - The Miami Hurricane

Harrison Ford Ditches Meat and Dairy and Says he is Vegetarian – The Beet

Harrison Ford isn't just Indiana Jones or the most famous Wookie-loving pilot in the Galaxy. Now he is adding to his many roles. After playing heroes as lovable as Han Solo, Indie and the original Jack Ryan of the big screen, Ford just yesterday announced that he was giving up meat and dairy "to help the environment."

Speaking about his new diet, Ford said: "I eat vegetables and fish, no dairy, no meat. I just decided I was tired of eating meat and I know it's not really good for the planet, and it's not really good for me." This follows his speech last fallatthe UN Climate Action Summit where he spoke about the environmental crisis and saving the Amazon rainforests.

Always fit, always preternaturally youthful and always on the move, Ford is another "cool guy" who has joined the ranks of plant-lovers. When Arnold Schwartzenegger and James Cameron speak out against meat and dairy, and the benefits of adopting a plant-based diet for their health and performance, guys sit up and listen. There is the usual discussion of "Where do I get my protein?" and "What the heck do I eat?" which are all good questions and The Beet has complete guides to the best sources of plant-based protein and 21 days of ready-to-cook recipes as part of our 21 Day Plant-Based Challenge. But less and less, do you hear the line of resistance that goes something like: Real men eat meat. And Vegetarianism is for girls. Because it's not.

Ford says his athletic body is due to his diet more than hitting the gym, according to a recent interview, and insists he doesn't "work out" like crazy.

Making an appearance on The Ellen DeGeneres Show, he added: "I don't work out like crazy; I just, I work out a bit. I ride bikes and I play tennis and a little bit."

Meanwhile, Harrison has claimed the only people that can save the world are "angry" young people.

The Hollywood icon, now 77, appeared on Tuesday's edition of The Ellen DeGeneres Show, and went into detail about delivering his speech to save the Amazon rain forest last fall at the UN Climate Action Summit.

Asked if he was nervous beforehe gave the speech, the Oscar-nominated actor replied, 'Not until I [got] there - I don't have enough sense to be.'

'I was in this room, I was on a dais ... and everybody else was a head-of-state and I thought, "Oh man they made some big mistake here,"' Ford said. 'But then they let me talk about what I wanted to talk about - which is the environment.' The Daily Mail of London broke the story.

"We've been talking about saving the Amazon for 30 years. We're still talking about it," Ford continued. "The world's largest rain forest, the Amazon is crucial to any climate change solution for its capacity to sequester carbon, for its biodiversity, for its freshwater, for the air we breathe, for our morality. And it is on fire. When a room in your house is on fire, you don't say, 'there is a fire in a room in my house.' You say, 'My house is on fire,' and we only have one house ... They are the young people who, frankly, we have failed - who are angry, who are organized, who are capable of making a difference. The most important thing that we can do for them is to get the hell out of their way."

On a lighter note, Ellen accused Ford of riding an electric-powered bike, a fact he adamantly denied.

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Harrison Ford Ditches Meat and Dairy and Says he is Vegetarian - The Beet

A wider platter – The Indian Express

Written by Nayanjot Lahiri | Updated: February 25, 2020 2:02:33 am A promotional image for Historical Gastronomica. (File) With an impressive variety of meats, fish, and fowl, the cuisine of the Harappan city dwellers would even today be considered a gourmands delight.

Harappan food was rich in all kinds of fleshy delights. Indeed, with an impressive variety of meats, fish and fowl, the cuisine of the Harappan city dwellers would even today be considered a gourmands delight.

Before giving a graphic description of the nourishing non-vegetarian fare that they delighted in consuming, perhaps I should mention how food remains are studied. Within the material culture that has survived, there is the garbage of everyday life found at archaeological sites around the production and consumption of food vast quantities of broken and discarded pottery, chewed and charred animal bones, sundry cereals and seeds of fruits and implements used in producing and processing food. Such artefacts are now studied through scientific techniques that can even indicate whether stone tools were used to cut meat or wild grass, and whether grinding stones mashed mangoes or cereals.

In India, unfortunately, we dont get direct evidence of a meal, that is, of what ancient people consumed at a particular time and day because this comes from the stomachs and the excreta of past people. Neither of these have survived in archaeological contexts here.

Opinion | Harappan meat-eaters, Lutyens vegetarians

Occasionally, a single sample on a site will yield large amounts of material. At the Harappan city of Surkotada, charred lumps of carbonised seeds were discovered from an earthen pot. Two of the charred lumps yielded nearly 600 specimens, an overwhelming majority of which were from wild plants. Only about 7 per cent were identified as being of cereals. The cereals were millets, wild and cultivated, wild grasses, nuts, and weeds. This cannot give clues to the relative importance of different cereals because the sample only reflects a moment in time.

Plant remains from Harappan sites reveal the entire repertoire, from cereals and lentils to fruits and vegetables, and even the spices used. Recognising grains is easy and has been done for nearly a century since the discovery of Mohenjodaro and Harappa because burnt cereals survive rather well and sometimes also leave an imprint on clay. Among vegetables and fruits, it is usually their seeds that are identified. More recently, the archaeologist Arunima Kashyap has recovered and identified at Harappan Farmana (in rural Haryana), starch granules from pots, grinding stones, and teeth, showing the processing, cooking and consumption of mangoes, bananas and garlic. What was left over after the household ate was evidently fed to their animals since the same starch granules were scraped off the teeth from cattle remains found there.

The first thorough investigation of ancient animal remains from an archaeological site anywhere in the Indian subcontinent was done at Mohenjodaro, published in 1931 in the first excavation report of the city. Written by Colonel R B Seymour Sewell and B S Guha, no less than 37 species were identified. There were domesticated and wild animals and included a considerable frequency of humped cattle, pig, and fish. Apparently, gharials and turtles, remains of which in many cases have been burnt, indicate that such animals formed part of the food of that city. Since then, as a 1994 article by P K Thomas and P P Joglekar revealed, there have been some two dozen Harappan sites whose animal remains are reported. Interestingly, cattle bones account for more than 70 per cent of the bones and, in fact, any Harappan site where bones have been found, without exception, has yielded cattle bones. Evidently, while cattle were used for agricultural operations and as draught animals, their meat was vastly enjoyed. Mutton was the other food that was commonly consumed as were pigs.

Animal teeth have also been studied to understand when the victims were killed. At Harappan Oriyo Timbo (in Gujarat), nearly 15,000 animal bones were recovered and annular rings accurately fixed the age and season of death of fauna. The microscopic annuli on a dental substance known as cementum was carefully assessed. What these revealed was that cattle, sheep and goat were slaughtered from March to July. Usually, very young animals were not killed, and slaughtering was most common in cattle samples at 30 months and 18 months in sheep/goat. Mature animals bones were also very common which underlines that adult animals were valued for their productive capacity.

The animals that Harappans kept and consumed is rather well known. What is less known is the range of wild animals enjoyed by them and the fact that these contributed greatly to their diet. Various types of deer and antelopes were hunted, and many varieties of birds, turtles, fish, crabs and molluscs were found as Thomas and Joglekar point out, in the kitchen refuse. We also know that ancient Punjabis at the city of Harappa enjoyed marine catfish.

Among wild animals, from Gujarats Kuntasi and Shikarpur, bones of wild ass with cut marks and evidence of charring underlines that they were hunted for food. Gujarats Harappan sites, as Shibani Boses just published book on Mega Mammals in Ancient India reveals, also show the presence of rhinoceros. It is animals that are normally eaten which find their way into archaeological deposits and that is likely to be the reason why these bones are so commonly found. In the case of Nausharo in Baluchistan, rhino bones were found in a hollow along with trash. What Bose also points out is the consumption of rhino meat in historical India and that texts on Indian medicine like the Caraka Samhita attribute definite health benefits to it.

Some scriptures did frown on or had misgivings about killing and consumption of animals. The Satapatha Brahmana, an ancient Indian religious text that forms part of the Vedic corpus, is full of fine detail about sacrificial ritual, and the eater of meat is said to be eaten in his next birth by the animal killed. Regardless of these occasional scriptural impediments, the general picture is of an ancient populace not just carnivorous but eagerly so.

All this should give pause to modern advocates of vegetarianism who want to make ancient Indians in general and Harappans in particular appear to be like them. Harappans would most certainly have scoffed at such attempts, even as they chomped through chunks of roasted cattle and pig.

The writer is professor of history at Ashoka University

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A wider platter - The Indian Express

Sunway University Researchers Recognised with the Vice-Chancellor’s Research Award – QS WOW News

In its aim towards becoming the countrys international education hub, Sunway University is moving forward in its pursuit of excellence not only in academia but also through innovative research.

At the end of last year, four Sunway University researchers were recognised with the Vice-Chancellors Research Award. The recipients were; Associate Professor Dr Yong Min Hooi from the Department of Psychology who received the Special Research Award, Professor Saidur Rahman of the Research Centre for Nano-Materials and Energy Technology with the Award for Achievement in Research, Dr Ayaz Anwar of the Department of Biological Sciences and Dr Hassanudin Mohd Thas Thaker from the Department of Economics and Finance who each received the Award for Achievement in Research for Early Career Researcher.

Associate Professor Dr Yong Min Hoois research focusses on ageing, specifically, executive function and social cognition in older adults. Dr Yong received the Long-Term Research Grant Scheme (LRGS) from the Ministry of Education Malaysia, amounting to RM2.47 million for a 5-year research on Successful ageing: Evidence-based interventions to delay ageing-related decline. This is first single largest grant received in the history of Sunway University. The five-year term from 1 December 2019, scheduled to be completed by 30 November 2024, is categorised under the Aging cluster within Health research cluster and governed under the Sunway Universitys Research Ethics Committee.

Dr Yong previously received various grants from the Newton-Ungku Omar Fund from British Council and the Malaysian Industry-Government Group for High Technology (MIGHT), Arts and Humanities Research Council UK, and Fundamental Research Grant Scheme (FRGS) from Ministry of Higher Education.

Professor Saidur Rahman is Head of the Research Centre for Nano-Materials and Energy Technology. His research focus is in the area of emerging nano-materials, applications in harvesting and storing of solar energy. He has been recognised as a highly cited researcher, listed as the top 1% researchers for most cited documents in his research field of nanofluids for the last 6 years (2014-2019).

Dr Ayaz Anwars current research projects focus on nanomedicine and medicinal chemistry for the development of antimicrobial chemotherapy. His research on silver nanoparticles targeting brain eating amoeba gained international coverage and was featured in the New York Times.

Dr Hassanudin Mohd Thas Thaker research focus in Islamic banking and finance, real estate finance, financial markets, derivatives, and economics has been recognised internationally, earning him the Emerald Literati award in 2016.

Sunway University has 9 research centres and one research group under its roof where research across various fields of study is encouraged.

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Sunway University Researchers Recognised with the Vice-Chancellor's Research Award - QS WOW News

Sleuths Uncover Web of Research Fraud in 400+ Papers From China – The Wire

Elisabeth Bik, the microbiologist and research integrity consultant noted for unearthing evidence of research misconduct, tweeted on February 21that she and some others had uncovered over 400 scientific papers that all share a very similar title layout, graph layout, and (most importantly) the same Western blot layout indicating an organised web of potential fraud. She also expressed concern that there might be hundreds of papers more, and that she and her collaborators may just have spotted the obviously fraudulent ones.

Western blotting is a technique that microbiologists employ to identify the proteins present in a tissue sample. As an analytical technique involving real-world materials, no two images of western blots are supposed to look alike, and similarities suggest the image may have been manipulated, inadvertently or otherwise.

Guided by this and similar giveaways, Bik, @SmutClyde, @mortenoxe and @TigerBB8 (all Twitter handles of unidentified persons), report as written by Bik in ablog post that the Western blot bands in all 400+ papers are all very regularly spaced and have a smooth appearance in the shape of a dumbbell or tadpole, without any of the usual smudges or stains. All bands are placed on similar looking backgrounds, suggesting they were copy-pasted from other sources or computer generated.

Bik also notes that most of the papers, though not all, were published in only six journals: Artificial Cells Nanomedicine and Biotechnology,Journal of Cellular Biochemistry,Biomedicine & Pharmacotherapy,Experimental and Molecular Pathology,Journal of Cellular Physiology, andCellular Physiology and Biochemistry, all maintained reputed publishers and importantly all of them peer-reviewed.

As a result, the discovery of the problem papers has prompted concerns about the ability of peer-review to check research misconduct in the scientific community.

Indeed, when Bik writes, Finding these fabricated images should not rely solely on the work of unpaid volunteers, she evidently means herself and her collaborators but her words also apply to peer-reviewers, who are unpaid for their work and often lack both the resources and the inclination to investigate each paper in close detail. As a result, peer-review is often not the insurmountable defence some proclaim it to be, nor are peer-reviewed journals as free of bogus science as they claim to be.

As Madhusudhan Raman, a postdoctoral scholar at the Tata Institute of Fundamental Research, Mumbai,wrote inThe Wire, any attempt to radically change the nature of peer-review must necessarily be accompanied by a change in the way the referees are compensated for their time and effort, especially within academia.

A PubPeer user who goes by Indigofera Tanganyikensis first identified the problem in two papers (thisandthis) both published by Chinese researchers. On February 17 this year, a little under a week before Bik published her blog post, two American researchers Jennifer A. Byrne and Jana Christopher published an articlediscussing similar research misconduct based on 17 papers they had discovered.

According to Bik, As it turns out, Byrne and Christophers publication describes the exact same set of papers that our small team of image forensics detectives had been working on in the past month.

These sleuths, as @SmutClydewrote on Leonid Schneiders blog, believe they have stumbled upon at least one paper mill. To quote (selectively) from Biks post,

A paper mill is a shady company that produces scientific papers on demand. They sell these papers to [people] who do not have any time in their educational program to actually do research. Authorships on ready-to-submit or already-accepted papers are sold to medical students for hefty amounts. Whether or not the experiments described in these papers has actually been performed is not clear. Some of these paper mills might have laboratories producing actual images or results, but such images might be sold to multiple authors to represent different experiments. Thus, the data included in these papers is often falsified or fabricated.

The mills seem to have been hired by Chinese clinicians affiliated to various medical colleges and hospitals in China (234 of the 400+ papers have been authored by people affiliated to institutions in Shandong province). The papers were all published between 2016 and 2020. @SmutClyde wrote that after they publicised their findings, including thedataset of papers they had identified as potentially fraudulent (and which they continue to update), an author of one of the papers wrote in:

Being as low as grains of dust of the world, countless junior doctors, including those younger [than] me, look down upon the act of faking papers. But the system in China is just like that, you cant really fight against it. Without papers, you dont get promotion; without a promotion, you can hardly feed your family. I also want to have some time to do scientific research, but its impossible. During the day, I have outpatient surgeries; after work, I have to take care of my kids. I have only a little bit time to myself after 10 pm, but this is far from being enough because scientific research demands big trunks of time. The current environment in China is like that.

Considering how the peer-review of all of those journals have failed, what the detectives have found effectively represents a large volume of unscientific data entering the scientific literature, funnelled predominantly by Chinese researchers who probably hired a paper mill to help meet the publishing requirements set by their respective institutions. Bik wrote that it is of great concern to see that this specific paper mill has successfully infected particular journals and that it is very alarming to see that journal editors do not appear to have noticed the similarities between dozens of papers published in their journals.

This said, the note from the unnamed Chinese author indicates the source of the problem is hardly new or even confined to China.

For example, until Prakash Javadekar, then the Union human resource development minister, said in mid-2017 that college teachers would not be required to undertake research to qualify for promotions, people who had not trained for research and have since been embedded in environments not properly equipped to support research were forced to conduct research, and publish papers.

Javadekar is to be loudly applauded and congratulated for taking this measure,Pushkar wrote forThe Wireat the time. The research requirement in the [Academic Performance Indicators] for college teachers was a travesty. All that it achieved was a proliferation of fake journals for college teachers to publish in.

Indeed, India has come to be known the fake journals capital of the world, partly as a result of requiring people who cannot undertake research to undertake research, and partly because research productivity has become one of the core measures of determining whether a country is a scientific superpower.

For another example, the journalNaturereportedthat Pakistans research output increased the most among all countries in the world by 21% in 2018, a feat that it dubbed a phenomenal success. However, as Anjum Altaf, former provost of Karachis Habib University and a famous teacher, subsequentlytoldThe Wire, The volume of third-rate publications in Pakistan has increased greatly simply because [Pakistans Higher Education Commission] introduced a tenure-track system and required publications for promotion.

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Sleuths Uncover Web of Research Fraud in 400+ Papers From China - The Wire

Medical industry partly to blame for Paltrow’s horrible ‘Goop Lab’ – Press of Atlantic City

In the past few years, as a surgeon, I have become increasingly aware of the scourge of the wellness industry. I am seeing patients who opt for diets, supplements or magical therapies instead of the less seductive though scientifically grounded medicine I have to offer. Like everyone else, I too am constantly bombarded with messages in advertisements and from well-meaning friends as to how this diet or that vitamin is the key to health, longevity, beauty and status.

At the moment, every time I turn on Netflix The Goop Lab appears as a show that I might enjoy watching. Given that Goop exists on a platform of misinformation, privilege and anti-science rhetoric, its safe to say that as a surgeon and health communicator I will not be contributing to actress Gwyneth Paltrows growing wealth by watching her pseudoscience.

The growth of Goop and of the multitrillion-dollar wellness industry is cause for concern. On the surface, it looks full of promise and hope. Dig just a little deeper, beyond the claims of all-natural miracles the energy healing, the cold therapy, the anti-aging treatments and what we find is at best a waste of money and at worst harmful methods that actually compromise your health. Research has shown that for those with cancer, using alternative therapies such as homeopathy or specialized diets led to people opting away from proven treatments and an increased risk of dying from that cancer. Make no mistake: What wellness sells is by no means harmless.

For doctors such as myself, the rise of this brand of wellness is distressing. However, medicine as a profession and a science has no doubt played a part in the genesis and growth of big wellness. For virtually the whole of its existence, medicine has disenfranchised women and to varying degrees continues to do so. Even as medicine has modernized with an emphasis on autonomy and resolving bias, it remains at times paternalistic and patriarchal. It comes as no surprise then that women are overrepresented in the wellness industry, both as consumers and providers.

Medical care has not accounted for what women need and want. Women are more often dissatisfied with medical care, feeling that it has failed to recognize their autonomy and unique biological and social needs. Women are more likely to have chronic illness and autoimmune diseases, both of which can be challenging to treat from a doctors point of view but even more challenging to live with.

Even among diseases for which we have made tremendous strides in treatment, female patients are often left behind. Women who experience heart disease are more likely to be subjected to misdiagnosis, inadequate treatment and poor outcomes. In the realm of pain management, women are more likely to be given anti-anxiety medication than painkillers, diminishing their experience with pain. Even in endometriosis, women face a wait of seven years on average until diagnosis. Women also remain underrepresented in research trials, with that absence translating to science that serves men well but lacks understanding of womens bodies and experiences. These differences are not explained wholly by biology but rather structural biases across the medical industry.

If you feel excluded by medicine, why wouldnt you look elsewhere? The wellness industry has filled a gap in health and well-being that the practice and science of medicine have left wide open. The wellness industry purports to be everything that conventional medicine is not egalitarian, hopeful and accessible. Even though it is elitist, privileged and full of falsehoods, it does not matter to those who seek its comfort. Its offering something that my profession, despite advances and improvements, has not been able to deliver consistently.

Last month, the head of Britains National Health Service delivered a stinging assessment of the growth of the wellness industry and the harms that the willful ignorance of science is bringing. Although it is entirely appropriate that health-care professionals fight the rising tide of medical misinformation, if we do not recognize and address our own role in its creation, the fight will be futile. Medicine needs to understand that we have contributed to the Goops of the world. The elevation of expensive and even harmful remedies is in part our own doing.

To truly ensure peoples safety, medicine must of course denounce dangerous, unnecessary and expensive snake oil, but it must also turn our attention inward and provide care that people need and want, communicated with compassion and supporting their autonomy. If we are to ensure that people are protected against medical half-truths and harmful remedies, my profession must move far away from the patriarchal practices that have alienated so many. Medicine has helped create this problem, and we must do better to be its solution.

Nikki Stamp is a heart and lung surgeon in Perth, Australia.

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Medical industry partly to blame for Paltrow's horrible 'Goop Lab' - Press of Atlantic City

Medical Technology in 2020: the latest on Tech, Biotech and Beauty Tech in the Medical Space – CloutNews

Healthcare is evolving at an exponential pace. Healthcare is an industry that is currently being transformed using the latest technology; so it can meet the challenges it is facing in the 21st century. Technology can help healthcare organizations meet growing demand and efficiently operate to deliver better patient care. We had the chance to chat with Dr. Konstantin Rubinov, an NYC Dental Surgeon specializing in longevity and anti-aging with a focus on regenerative and cosmetic medicine.

Artificial intelligence (AI) is the ability of a computer program or a machine to think and learn with the help of intricate, pre-programmed algorithms. It is also a field of study which tries to make computers smart. As machines become increasingly capable, mental facilities once thought to require solely human intelligence are removed from the definition. AI in healthcare aims to improve patient outcomes by assisting doctors and physicians in using the medical knowledge; which has been analyzed, downloaded and memorized by these systems, and provides superb clinical and medical solutions to modern medical problems that patients face.

AI systems have the potential to provide physicians and researchers with relevant, live, high quality data; from electronic health records (EHRs) to serve immediate needs. The first uses of AI are likely to be in the field of guided surgery and patient triage reports Dr. Rubinov. We are currently seeing increased surgical precision even over 3D printed surgical guides with companies like ClaroNav and XGuide, which are combining various types of 3D imaging technology to deliver real time robotic enabled surgical implant guidance.

A liquid Biopsy has the potential to monitor tumors in a way that is not invasive. The process separates cancer cells from blood samples and can completely transmogrify treatment for cancer through monitoring of the actual cancer cells by non-invasive means. To illustrate the difference, using todays available technologies, repeated biopsies are needed to study; the evolving tumor and present a big issue for the patient. It can be anticipated that in a few years, liquid biopsy will even become a supplementary procedure; to tissue biopsy procedures, says Rubinov. This technology has proven to be much more effective and detects when a disease worsens even before a CT scan can. Considering that oral and pharyngeal cancer is on the rise in the US; this advanced diagnostic technology has immediate daily application in our practice, states Dr. Rubinov

Anti-Aging Medicine, Plastic Surgery and the field of Facial Aesthetics is booming thanks to all the latest available bio-technologies in Cosmetic Medicine. As a veteran cosmetic dentist with 10 years of facial esthetics experience, Dr. Rubinov shares some of the latest Beauty Tech trends in Aesthetic medicine in 2020. Dr. Rubinov believes the biggest advances are in biological material science. The bio-active potential of new injectable Hyaluronic acid fillers and bio-stimulating materials like Sculptra, Radiesse and PRP are showing that we can reverse time when it comes to anti-aging and rejuvenation procedures by stimulating collagen and soft tissues even as we get older, says Rubinov.

One of Dr. Rubinovs favorite bio technologies is the use of blood plasma (PRP) and (PRF) in regenerative aesthetic medicine. While he uses Blood plasma routinely during surgical procedures to help regenerate both hard and soft tissues in the mouth; Using PRP in conjunction with the Derma Pen 4 yields the most beautiful results in facial rejuvenation. With microneedling PRP or The Vampire Facial as the procedure is called, we are able to flood the skin with growth factors and progenitor cells and watch the skin repair itself from years of sun and environmental damage. You become a believer the second you see 20 year old acne scars disappear, says Dr. Rubinov.

In terms of Beauty Tech, European brands are much ahead of their American counterparts. At the 17th Aesthetic and Anti-Aging Medicine World Congress in Monte-Carlo 2019; SkinTech Pharma Group and the cosmetic pharmaceutical giant Allergan devoted huge sections of the show with, live demonstrations of their latest medical bio technologies. Many companies brought tech to the show, with the goal of making skincare and beauty more personal for their customers and providers. 3D Facial analyzers helped with virtual simulations letting clients see exactly what their before and after results will look like. Modface and LOreal both showcased a diagnostic tool to enable customers to virtually try on makeup. And Coty, a pheromone driven fragrance company has an Artificial Intelligence tool which allows one to find the perfect scent match.

Not only are these large brands investing in this futuristic spin on the beauty industry but so are smaller companies such as indie brands and startups like RegenLab PRP. Investments in this way are being made from everywhere because the barrier to entry is much lower; technology is not as expensive as it used to be and the analytics for these purposes are also more readily available, says Rubinov.

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Medical Technology in 2020: the latest on Tech, Biotech and Beauty Tech in the Medical Space - CloutNews

Black Skin Care Influencers Are Leading the Social Skincare Movement – STYLECASTER

Its a universally acknowledged truth that the topic of skincare is more popular than ever. An industry once hyper-focused on pimples and anti-aging has grown to prioritize wellness and become synonymous (and often conflated) with self-care. Once wildly personal, skincare has gone public, often verging on theaterwhether its a faux-casual selfie of someone eating pasta while masking or a highly produced video of a celebrity washing their face and getting dragged for doing it badly. Theres also an abundance of advice offered by experts and enthusiasts, sometimes the two unable to agree (and people having a hard time deciding whos right).

The world of skincare, in its sheet-masking, serum-applying, carefully-documented glory, is often touted as the great unifier for people of all skin tones, skin types and needs. Theres something for everyone, it claims, the inherent invisibility of products allowing the industry to be slow in its focus on inclusivity and avoid the discussion in a way the makeup sector never could.

Skincare remains another site of privilege where Black people continue the fight to be seen and heard.

Skin of color, in its rich variation of tone and slowness to age, is seen as impenetrable and strong, much like the people who possess it. Its a fallacy with complex ties to a system that has historically ignored Black people or purposefully denied them safe, effective care, and still makes it difficult for us to gain knowledge and achieve goals too.

Before the internet, skincare advice came by way of friends, family and magazines. It was in these spaces that one learned how to shrink a blemish, ways to slow down the skin aging process, and which products were necessary for a dewy glow. It was beauty secrets whispered and passed down, lessons learned by watching and copying.

But Black people rarely got to see their unique challenges addressed outside of trusted circles since these narratives were routinely overlooked by print magazines claiming to service everyone. Things changed with the advent of social media, where previously marginalized communities were able to connect in quasi-public spaces about the shared issues they were facing and address the outlets and brands that had been ignoring them all along.

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Melanoma Facts in Skin of Color// : : Malignant melanoma is a skin cancer of melanin producing cells which protect skin from harmful effects of the sun. : People of color are less likely than caucasians to get melanoma but they are much more likely to die from it when they do due to DELAY in DETECTION or ADVANCED DISEASE. : UV radiation remains the major risk factor in melanoma however in POC, it mostly presents in NON-sun exposed places such as the palms, soles, fingernails & toe nails, mouth, genitals & so are often missed. : UV-induced melanomas in POC does still occur given the wide range in shades of complexions, from very fair to very dark. : POC should perform regular monthly head to toe self exams of their skin. Unusual moles, scars, sores, lumps, blemishes or changes in skin texture should be professionally evaluated. : Most importantly, a thorough skin examination including of nails, oral cavity, gums, palms, soles, eyes & genital area should be performed regularly by a dermatologist. : Dark lesions on gums & streaks in nails should be monitored for malignant transformation. : Other risk factors for melanoma in POC include: albinism, burn scars, radiation therapy, trauma, immune suppression and preexisting moles & should be regular evaluated. #melanoma #melanomaawareness #brownskinderm #skininclusive #skinofcolor #slickwoods #skincancer

A post shared by Brown Skin Derm (@brownskinderm) on Nov 22, 2019 at 10:23am PST

Leading the charge are dermatologists, estheticians and enthusiasts, who talk about things like hyperpigmentation, how to identify skin cancer (often caught at a much later stage in Black women) and answer questions that are often still ignored by mainstream media.

If you look at major print magazines before the advent of online beauty blogs, most skincare articles and product advertisements within them did not speak to women of color, says dermatology resident Adeline Kikam, known as the @brownskinderm on social media. Weve just recently started talking about how to care for Black skin and hair on a national level.

These thought leaders with proven influence have shifted the very concept of authority. Whereas outlets and publications were once on the cutting edge, determining the trends and uncovering the next new thing, the roles are now often reversed.

One such influencer is Nayamka Roberts (also known as @LaBeautyologist), a trusted expert in the skincare space, thanks in part to her innovative 60-second rule. But it didnt start out that way. It took a while to find her people, Roberts tells me when we catch up via phone, noting that when she launched her Youtube channel in 2016, no one really cared about skincare or talked about it. Before focusing on skincare, she dabbled in natural hair and food but says the more she spoke about skincare, the more she realized people needed help.

Roberts, who notes she is the only esthetician followed by Barack Obama on Twitter, has nearly 150K followers on the platform, many of whom look to her for guidance about achieving glowy, luminous skin. Her 60-second rulewhich she says is an ideal time frame for allowing the cleansers ingredients to interact with your skin (and for you to interact with yourself), has become so big it often loses attribution. She, like many women of color who have had ideas or disrupted spaces, has seen her concept outsize her, co-opted into mainstream discourse and often leaving her nameless.

And while Roberts acknowledges the ways her work has outgrown her influence, she ultimately wants to educate. I dont really want people to be dependent on brands or even dependent on me, its all about empowering people to know how to take care of themselves, she says.

Dermatologists have also found their way into the movement, using their clinical knowledge to intervene in a space that has often overlooked women of color. Kikam uses her platform as a way to inform and educate, dispelling common myths and sharing products that speak to common concerns for skin of color. I wanted people of color to have a trusted space of evidence-based medicine related to their skin, she says. Since starting her Instagram in 2017, her community has gone global and grown increasingly diverse.

These thought leaders with proven influence have shifted the very concept of authority.

People of color everywhere demand to see themselves reflected in the way skincare is discussed, she explains. Unlike many other platforms her size, Kikam touches on lasers and aesthetics, a space Black people have been historically shut out of or hesitant to discuss due to cultural norms and ideologies that suggest black doesnt crack. Her willingness to shed light on these topics has created a judgment-free zone, where people are able to open up about conditions theyre often too embarrassed or nervous to discuss.

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//Lasers work by using wavelengths of light specific to & well absorbed by target structures in skin termed chromophores (melanin, collagen,hemoglobin, water, DNA or a foreign substance like tattoo ink) to yield a therapeutic outcome w/ minimal damage to surrounding skin. : skin of color' has unique characteristics that pose challenges to laser therapy; increased epidermal melanin, easily altered melanocytes(associated w/ greater post procedure pigment complications) & reactive fibroblast (promotes scarring). : #melanin has a wide absorption spectrum ranging from 2501200 nm, thus all visiblelight & near-infrared dermatologic lasers currently used in dermatology can target melanin. : At issue in SOC is epidermal melanin absorption of laser energy with resultant heat injury leading to hyperpigmentation & scar formation. : The safest wavelengths forSOC are those in the near infrared range; the 800810nm diode & the 1064nm (Nd:YAG) lasers most especially. Their longer wavelengths bypass the topmost epidermal layer of #skin prone to damage. : Longer wave-length lasers allow targeting of deeper structures in the dermis of skin such as hair while sparing the epidermis. : Contrary to popular misconception, lasers can be used in darker skin types albeit more cautiously, selectively & appropriately given greater risks of #hyperpigmentation & #scarring. Top uses of Lasers in SOC: #hairremoval Photo-rejuvenation: fine lines wrinkling, mottled pigmentation, Benign growths such as #dermatosispapulosanigra Skin tightening Pseudo-folliculitis #tattoo removal #acnescars Stretch Marks

A post shared by Brown Skin Derm (@brownskinderm) on Dec 5, 2019 at 3:58pm PST

Shes also one of few dermatologists to discuss the long term effects of skin bleaching and conditions like hidradenitis suppurativa, an autoinflammatory condition that disproportionately affects Black women and results in painful lumps and discharge in areas like the groin and armpit. By being able to articulate her symptoms better to her primary care doctor and bringing up the possibility that she may have HS based on what she had seen on my page, she was able to convince her primary care doctor to refer her to a dermatologist, she shared.

Kikam says this happens often and while shes happy to be part of pushing the conversation, shes cautious of her role in a highly commercialized space. I think the information on skincare needs to be accessible and affordable across all classes and not come off as elitist and exploitative.

True inclusivity is specific and meets people where theyre at rather than demanding it happen the other way around.

Its this work that pushes the conversation forward, but the skincare industry still has a long way to go. True inclusivity is specific and meets people where theyre at rather than demanding it happen the other way around. Brands and publications could take a page from Kikam and Robertss books, and use their platforms to center and consider these skincare concerns rather than add them in later or pretend they dont exist.

We need education in both the clinical and social spaces, where people of color are foregrounded and given the same attention as their white counterparts. Until then, skincare remains another site of privilege where Black people continue the fight to be seen and heard.

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Black Skin Care Influencers Are Leading the Social Skincare Movement - STYLECASTER

Silicon Valley startup tries to move executive physicals beyond the C-suite – STAT

SAN FRANCISCO The three-martini lunch may be on the decline, but many big companies still reward their C-suite with that traditional corporate perk: getting poked and prodded as part of an executive physical that can carry a five-digit price tag.

Now, a Silicon Valley startup wants to reimagine these medical workups by offering a version for a broader audience, one that would run 75 minutes and have patients undergo an MRI scan and genetic analysis, among other testing.

You can pay $20,000 and go to Mayo and spend a weekend there. But thats not ever really going to be scalable, said Jeffrey Kaditz, co-founder and CEO of Q Bio, which announced on Thursday that it raised $40 million from leading Silicon Valley venture capital investors.

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Q Bio is interested in a different question, Kaditz said: What is the most valuable information we can collect about your body, in as short a period of time as possible, as efficiently as possible, and non-invasively as possible?

It will still not be cheap. The price for a yearlong membership to Q Bios service starts at $3,500 out of pocket, with more comprehensive options available for $6,500 and $15,000.

By comparison, major U.S. hospitals offer executive physical packages ranging from $1,700 to $10,000, according to a research letter published in JAMA last year. The most famous of the bunch is the Mayo Clinics executive health program, founded more than four decades ago; its price tag varies based on factors including age and family history. Then theres Human Longevity Inc., the company formerly led by the genomics pioneer Craig Venter, which in 2015 launched an extraordinarily in-depth $25,000 physical.

When people sign up for Q Bios service, the startup asks them to list their health care providers as well as clinics and hospitals where theyve been seen; the company then aggregates and digitizes those records. Two weeks after the exam, the company generates a report based on the results of the MRI as well as testing of blood, urine, and saliva samples.

The report, which can be used by the customers health care providers, surfaces the most important and potentially concerning findings up top. Q Bio wants people to undergo follow-up exams so that changes in their baseline can be tracked over time.

That approach may draw criticism.

Experts say there is not strong evidence that such testing and monitoring offer widespread health benefits, or that it can save the health care system money over time. Theres also the risk of false positives, if something turned up in a medical workup leads to unnecessary and potentially harmful follow-up testing or medical interventions.

Q Bios service stands in contrast to the approach more commonly seen in medicine, in which patients are compared to population distributions and population norms, said Vijay Pande, the general partner at the VC firm Andreessen Horowitz who led Q Bios new Series B funding. That makes sense when you dont have a baseline for yourself, Pande said.

Q Bios approach, on the other hand, recognizes that you can actually be within tolerance of a population norm, but be way out of scope for your personal norm, Pande said. He said hes optimistic that that approach, along with the wide range of measurements the company is collecting, has potential to dramatically minimize false positives.

Kaditz said the company tried to be conservative in deciding which things in the body to monitor, opting to capture only that which could be measured in a reproducible way and would be useful for doctors. For example, Q Bio steered clear of measuring the microbiome. And in contrast to competing medical workups that pitch whole genome sequencing, Q Bio decided to analyze a panel of just 147 genes.

One of Q Bios co-founders is Michael Snyder, a Stanford geneticist who has been an evangelist and a human guinea pig for an approach to precision medicine involving intensive health tracking over time. Last year, Synder and his team reported results from a longitudinal study of 109 people who underwent an initial intensive physical and genetic analysis and then provided blood and other samples every quarter for a number of years. The researchers identified more than 67 clinically actionable health discoveries.

Q Bio, founded in late 2015, came out of stealth mode on Thursday. Kaditz wouldnt say how many people have paid to get exams since the Q Center opened in Silicon Valley late last year, but he said demand from locals and people who have flown in has been so high the company had to create a waiting list.

Kaditz said there have been instances in which executives who have paid for a membership for themselves have proceeded to decide to cover it as a benefit for their C-suite or other employees. He wouldnt say how often thats happened.

With the new funds announced on Thursday, the company plans to open additional Q Centers in other U.S. cities and to invest in trying to line up deals with employers to cover memberships for their employees.

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Silicon Valley startup tries to move executive physicals beyond the C-suite - STAT

Mediterranean diet scores another win for longevity by improving microbiome – wlfi.com

Yet more bragging rights are in for the Mediterranean diet, long considered to be one of the healthiest in the world.

A new study published Monday in the BMJ journal Gut found that eating the Mediterranean diet for just one year altered the microbiome of elderly people in ways that improved brain function and would aid in longevity.

The study found the diet can inhibit production of inflammatory chemicals that can lead to loss of cognitive function, and prevent the development of chronic diseases such as diabetes, cancer and atherosclerosis.

'Our findings support the feasibility of changing the habitual diet to modulate the gut microbiota which in turn has the potential to promote healthier aging,' the study authors said.

About 60 tons of food pass through the average human's digestive tract in a lifetime, science says, exposing our insides to billions of different bacteria in addition to those we were born with. Many of those miniscule creatures play important roles -- good and bad -- in how well we absorb nutrients; the functionality of our immune response; and our energy and metabolism levels.

Science has shown that as we age, the types and amount of microbes found in the gut are reduced. A poor diet is especially common among the elderly in long-term residential care and those who live alone. Health and dental issues can also make it difficult for the elderly to eat a well-balanced diet.

As the diversity of bacteria diminishes, 'inflamm-aging' occurs, contributing to age-related inflammatory processes that can lead to cancer, neurological disorders and other diseases.

The study analyzed the gut microbiome of 612 elderly people from France, Italy, the Netherlands, Poland, and the United Kingdom before putting 323 of them on a special diet for a year.

While the diet was designed for the elderly, it was based on the Mediterranean principles of eating lots of fruits, vegetables, nuts, legumes, olive oil and fish, and little red meat, sugar and saturated fats.

The rest of the 65- to 79-year-olds in the study were asked to continue to eat as they always did for the same 12 months.

After the year was over, those who had followed the Mediterranean diet saw beneficial changes to the microbiome in their digestive system. The loss of bacterial diversity was slowed, and the production of potentially harmful inflammatory markers such as C-reactive protein and interleukin-17 were reduced.

At the same time, there was a growth of beneficial bacteria linked to improved memory and brain function, the study said. The diet also appeared to boost 'keystone' species, critical for a stable 'gut ecosystem' and which also slowed signs of frailty, such as walking speed and hand grip strength.

Nationality did not appear to matter. The findings were similar and consistent no matter where the people lived and no matter their age or weight, both of which influence the unique makeup of a person's microbiome.

The study is part of a larger randomized controlled trial of 1,200 people called the European Project on Nutrition in Elderly People or NU-AGE that began in 2012. Previous publications from the ongoing study found those who followed the diet closely had improved episodic memory and overall cognitive ability. Higher adherence to the diet also reduced the rate of bone loss in people with osteoporosis and improved blood pressure and arterial stiffness.

Discovering that the Mediterranean diet could affect the microbiome in a positive way isn't really surprising; the diet already has a stuffed shelf of scientific trophies. It's won gold medals in reducing the risk for diabetes, high cholesterol, dementia, memory loss, depression and breast cancer. Meals from the sunny Mediterranean region have also been linked to stronger bones, a healthier heart and longer life. Oh, and weight loss, too.

The diet features simple, plant-based cooking, with the majority of each meal focused on fruits and vegetables, whole grains, beans and seeds, with a few nuts and a heavy emphasis on extra virgin olive oil. Say goodbye to refined sugar and flour except on rare occasions. Fats other than olive oil, such as butter, are consumed rarely, if at all.

Meat can make a rare appearance, usually only to flavor a dish. Instead, meals may include eggs, dairy and poultry, but in much smaller portions than in the traditional Western diet. Fish, however, are a staple.

'It's more than a diet, it's a lifestyle,' said Atlanta registered dietitian Rahaf Al Bochi in an earlier interview.

'It also encourages eating with friends and family, socializing over meals, mindfully eating your favorite foods, as well as mindful movement and exercise,' said Al Bochi.

The Mediterranean diet has won first place in the US News and World Report's 'best diet' rankings for three years in a row. Anyone wanting to start the diet can do so in a few easy steps, say experts, by just adding healthy choices to their daily diet.

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Mediterranean diet scores another win for longevity by improving microbiome - wlfi.com

African Killfish Can Put Aging on Pause. Do They Hold the Secrets of Longevity? – Discover Magazine

The African turquoise killifish might not live long but, during development, it will stop growing and wait for better, wetter living conditions if it needs to.

If the pond the fish lives in dries up too much, killifish embryos can stop maturing for over six months. That pause can be even longer than their usual, uninterrupted lifespan. It appears that the fish emerge from these months relatively unscathed. Those embryos that put off growing live as long, and have as many offspring, as embryos that never pause, according to new research out in the journal Science.

What is remarkable is the embryos ability to stop damage that would happen over time, says study co-author Anne Brunet, a geneticist at Stanford University. The tiny tissues emerge in good condition and seem to have put off aging. By studying how the killifish genome changes for this months-long pause, researchers could one day prompt those alterations to preserve human organs as well.

Its not totally clear how killifish know it is time to stop growing. Not all enter this hibernation-like freeze, Brunet says, and those that do likely receive a signal from their mothers instructing them to do so. Her team was interested in finding out what all happens inside the embryos that end up waiting out those long months. As killifish bred in Brunets lab, she and her team examined genetic material from embryos before, during and after their stalled growth. Some genes werent as active as they are normally. This makes sense, Brunet says after all, the embryo isnt growing. But a few genes were operating at higher-than-usual levels. Some of these highly active genes were responsible for wrapping up large chunks of the genome and effectively turning them off, an efficient process that shutters several genes at once instead of a bunch of individual pauses, Brunet says.

Other genes active during this developmental hiatus have a role in muscle development. Brunet and her team didnt see how crucial they are for keeping the embryos healthy until they bred some of the fish with dysfunctional versions of these genes. When it came time for the growth pause, the brand-new muscle tissue in the genetically modified fish disintegrated. The team concluded that the reason these genes are normally so active in stalled embryos is because they keep those muscle cells from falling apart. Its not easy to maintain muscle its an active process of amendment, even if the cells dont proliferate. Without it, the muscle is no longer preserved, Brunet says. Thats really remarkable in hibernation.

Brunet and her team plan to investigate how these genetic changes can lead to healthy muscle cells. In other words, what is happening with the fish's hormones or metabolism that lets the embryonic muscle cells keep developing even in stasis? Further down the line, the scientists say it might be worth investigating whether the dormant stem cells in our own bodies share any of the same pause mechanisms as killifish.

That is very preliminary, but that is something that would be interesting, Brunet says. If the machinery is conserved, could that also function to preserve cells in tissues in the longterm? It will take much longer than a killifishs frozen development to find out.

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African Killfish Can Put Aging on Pause. Do They Hold the Secrets of Longevity? - Discover Magazine

Clearday Announces $3.2 Million Opportunity Zone Investment, New Headquarters, and Northeast San Antonio Site Transformation – Benzinga

First-of-its-kind investment for District 10 will be headquarters for multiple Clearday businesses and will offer innovative longevity care services at revitalized Northeast Corridor location

Clearday, Inc., a leading innovator in longevity care and wellness services, has made the first Opportunity Zone (OZ) investment in San Antonio District 10. With the investment, totaling a minimum of $3.2 million, Clearday has acquired and is transforming the medical building property located at 8800 Village Drive, adjacent to the Northeast Baptist Hospital campus. Upon completion of the building renovation, Clearday will consolidate its corporate headquarters as well as those of its Memory Care America subsidiary and other affiliate businesses at the site.

The company also announced that the first floor of the Northeast Corridor site will serve as the flagship location of Clearday Clubs, an innovative new daytime care destination serving those with Alzheimer's, dementia or other lifestyle limiting chronic health conditions. Clearday will launch the flagship Club along with Clubs in New Braunfels and Kerrville later this Spring, with plans for additional locations across Central Texas through the balance of 2020.

Clearday develops innovative options that address the widening gap between the longevity care needs of older Americans and the availability of affordable, high-quality care options. Each day, 10,000 Americans turn 65, and over 35 million people in the U.S. provide unpaid care to an adult over 50. The new daytime-only Clearday Club concept offers a high-quality care environment and uplifting member experience, at a price point less than 25% of the daily cost of residential care options.

"At Clearday, we are building an innovative, enduring business serving a great human need making excellent care more accessible and affordable for our loved ones as they age," said Clearday Chairman and CEO Jim Walesa. "We are thrilled to make this Northeast Corridor location the epicenter of our mission."

The federally designated Opportunity Zone program was initiated under the Tax Cuts and Jobs Act of 2017 and is designed to spur investment in lower-income communities by providing investors with tax breaks on capital gains if they reinvest the capital within the zones.

City Councilman Clayton Perry played an instrumental role in bringing the Clearday OZ investment to the District 10 community, helping Clearday identify the property and drive enthusiasm for the project among city officials and local businesses.

"This Clearday investment meets the true spirit of Opportunity Zone investing and will deliver revitalizing impact to our neighbors here in District 10 and all over San Antonio," said Perry. "The investment brings multiple growing businesses to the Northeast Corridor, along with a new, high-profile elder care facility that will provide both jobs and badly-needed, affordable senior care services to the local community."

ABOUT CLEARDAY

Clearday is an innovative longevity care and wellness company, with a modern, hopeful vision for making high quality care options more accessible, affordable, and empowering for older Americans and those who love them. Through our subsidiary Memory Care America (MCA), we operate a network of highly rated residential memory care communities in four U.S. states. With our Clearday Clubs concept, we are bringing the same standard of excellence found in our MCA residential facilities to a daytime-only community model that is dramatically less expensive than residential care options. Learn more about Clearday, Clearday Clubs at myclearday.com

View source version on businesswire.com: https://www.businesswire.com/news/home/20200221005420/en/

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Clearday Announces $3.2 Million Opportunity Zone Investment, New Headquarters, and Northeast San Antonio Site Transformation - Benzinga

Scientists Find a Wild Salamander That Hasn’t Moved From Its Spot For 7 Years – ScienceAlert

In the depths of a European cave, dwells what must be the laziest and most underwhelming of all creatures to have ever been called a dragon.With disturbingly fleshy-coloured skin, it has also earned the label of "human fish".

But the olm (Proteus anguinus), with its cute stubby limbs, is actually an amphibian - a type of salamander that has adapted to life in the eternal darkness of a skyless existence. This troglobitelifestyle has resulted in under-developed eyes covered by layers of skin, which led Charles Darwin torefer tothe speciesas "wrecks of ancient life".

Olm eyes can only detect the presence of light, but not much else. Thus, these little gill-adorned weirdos are essentially blind, but they make up for this with a keen sense of smell, underwater hearing, and the ability to detect movements in their watery home.

Between 2010 and 2018, researchers captured, tagged, and recaptured a number of olms in the caves of eastern Bosnia-Herzegovina.Based on the frequency of their encounters, they estimated there were 26 adult olms making themselves at home there; across these eight years, checking in on their research subjects revealed the animals had a rather limited movement range.

"The majority of recaptured individuals moved less than 10 metres (33 feet) during several years," wrote zoologist Gergely Balzs from Etvs Lornd University and colleaguesin their paper.

One of these individuals was even lazier than the rest. It was found in the exact same spot a crazy 2,569 days after it was first recorded. That's over seven years! But there are clues in olm biology that might explain this seemingly unbelievable feat.

(Javier balos Alvarez/Flickr/CC BY SA 2.0)

These little slackers have a lifespan of up to a century. For such slight creatures, up to 20 grams (0.7 ounces) and 30 centimetres long (12 inches), that's an impressive feat, so clearly they're doing something right.

"They are hanging around, doing almost nothing," Balzs told New Scientist.

This may be key to their longevity - the olms' strategy of primarily doing diddly-squat has been working well for them since they colonised caves around 20 million years ago.

Olms are able to achieve these epic heights of laziness thanks to a very low metabolism. They eat snails and crustaceans (which aren't exactly plentiful in the caves), but can survive for years without food.

The lack of predators within their cave systems would also encourage their couch potato ways, allowing olms to be perfectly safe just plonking themselves wherever.

Additionally, they only bother to breed about every 12 years. But when they do, they produce a clutch of around 35 of these spectacular looking eggs.

And it's not like they can't move - some olms have easily fled from nosy scientists, by wiggling their way through tens of metres of water. Nor can the scientists say for sure that their tagged subjects didn't go for a wonder while they weren't looking, before sneaking back to their favourite position.

(Arne Hodali/Wikimedia Commons/CC BY-SA 3.0)

But Balzs and colleagues found this group of olms has very low genetic diversity, suggesting the population recently shrunk, or has a high level of inbreeding, which again hints at a very sedentary life. A previous study suggested only their young might be dispersing.

This lack of genetic diversity was not found in Slovenian olm populations, so further research is required to see if the incredibly slow-paced lifestyle of the recently studied population is shared by the rest of the species.

"We can only speculate that animals feeding on a very low food supply, reproducing sporadically and living for a century are very energy cautious and limit their movements to the minimum," the researchers wrote.

Biologist Matthew Niemiller of the University of Alabama, who was not involved in the study, agrees. He told Science News:

"If you're a salamander trying to survive in this food-poor environment and you find a nice area to establish a home or territory - why would you leave?"

In this fast-paced, stressed-out world, perhaps we should all aspire to be a bit more like these olms.

This research was published in the Journal of Zoology.

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Scientists Find a Wild Salamander That Hasn't Moved From Its Spot For 7 Years - ScienceAlert

This Legend of a Volcano Erupting 37,000 Years Ago May Be The Oldest Story on Earth – ScienceAlert

A long, long time ago, the Indigenous Gunditjmara people the traditional owners of lands in southwest Victoria, Australia are said to have witnessed something truly remarkable.

An ancient oral tradition, passed down for countless generations, tells of how an ancestral creator-being transformed into the fiery volcano, Budj Bim. Almost 40,000 years later, new scientific evidence suggests this long-shared legend of the Dreaming could be much more than a myth.

New mineral-dating measurements conducted by Australian scientists highlight the possibility that the traditional telling of Budj Bim's origins may be an actual account of two historic volcanic eruptions that took place in the region about 37,000 years ago which, if true, might make this the oldest story ever told on Earth.

"If aspects of oral traditions pertaining to Budj Bim or its surrounding lava landforms reflect volcanic activity, this could be interpreted as evidence for these being some of the oldest oral traditions in existence," the researchers, led by geologist Erin Matchan from the University of Melbourne, write in their study.

Up until now, most evidence for the oldest known human habitation in Australia comes from radiocarbon dating or optically stimulated luminescence (OSL) dating, using samples of ancient charcoal, or sediments from rock shelters.

Unfortunately, a lack of both ceramic artefacts and permanent structures in the Indigenous Australian context makes finding archaeological samples a challenge. Only six sites in southeast Australia have been definitively dated to older than 30,000 years, the researchers say despite evidence from elsewhere in the country suggesting it could have been inhabited as far back as 65,000 years ago, or even older.

Luckily, recent technological advancements in an alternative technique called argonargon dating could provide new ways of dating volcanic rock in the southeast landscape, especially when coupled with interpretations of cultural knowledge, the authors suggest.

"The oral traditions of Australian Aboriginal peoples have enabled perpetuation of ecological knowledge across many generations, providing a valuable resource of archaeological information," Matchan and study co-author David Phillips explain in an article summarising their findings.

"Some surviving traditions appear to reference geological events such as volcanic eruptions, earthquakes, and meteorite impacts, and it has been proposed that some of these traditions may have been transmitted for thousands of years."

In the case of the now-extinct Budj Bim volcano, and another nearby inactive volcano located 40 kilometres (25 mils) away, called Tower Hill, we now have a better estimate of just how many thousands of years ago their ancient eruptions happened, thanks to the argonargon technique.

In the new research, the team dated a sample from a lava bomb hurled from the historic Tower Hill eruption, along with a sample of lava flow from Budj Bim's eruption.

The results suggest the eruptions may have been contemporaneous, with lava dated to 36,800 years ago ( 3,800 years) for Tower Hill, and 36,900 years ago ( 3,100 years) for Budj Bim.

Given Tower Hill's eruption was the most recent comparatively, the researchers suggest its eruption age "directly constrains a minimum age for human presence in Victoria".

That conclusion is based on the existence of a lone stone axe called the 'Bushfield axe' which was previously discovered buried beneatha layer of volcanic rock and ash from the eruption, and is therefore considered to be evidence of contemporaneous human occupation in the area.

As for whether the long-told oral tradition of Budj Bim truly chronicles these awesome, ancient volcanic outbursts, it's impossible to be sure. Some researchers say we need to be cautiousabout how we interpret stories from so long ago.

But we should also be curious.

"We in the West have only scratched the surface of understanding the longevity of Australian Indigenous oral histories," archaeologist Ian McNiven from Monash University told Science.

The findings are reported in Geology.

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This Legend of a Volcano Erupting 37,000 Years Ago May Be The Oldest Story on Earth - ScienceAlert

Human behavior at the intersection of many sciences – Dailyuw

People frequently ask themselves, Why did I do that? Attempting to understand how we react to and interact with changing environments has resulted in years of research on human behavior.

Neurobiologists and psychologists study the biological basis of how the brain responds under certain situations. Social scientists like anthropologists explain what factors guide our behavior and engineers are taking all these studies to design tools that enforce human interaction, intelligence, and growth.

Human nature is complex, and interdisciplinary considerations may help us answer some interesting questions about how people think, remember, and behave.

Things that are good for one's health and longevity such as finding mates, food, and children; the dopamine reward or evaluation system is important to recall that success, Sheri Mizumori, a professor in the department of psychology who studies behavioral neuroscience, said.

Dopamine is known as the feel-good neurotransmitter, a chemical messenger that relays information between neurons. It is released by the brain when we eat food, exercise, and crave sex, helping reinforce desirable behaviors by encoding values of rewards. Psychologists and neurologists have studied this through animal models that help explain how humans access their own memory to guide their actions.

From a young age, babies learn that if an outcome is not what they want, they will change, Mizumori said. Much of the brain has evolved to be a predictor of outcomes.

Memory can be thought of as a repository of past experiences that did and did not work. When we are placed in a new situation, we use strategies we learned from previous experiences to guide our actions.

You are driving behavior based on memory and [guiding] behavior correctly the next time, Mizumori said.

The brain uses decision circuits that integrate information about past values from memory and evaluates it against our motivational, or internal, state. Understanding how the brain can switch behaviors or learn new ones is known as flexible decision making.

Theoretical psychologists study human behavior from a philosophical and social standpoint. A commonly known study argues if nature or nurture genetic or acquired influences behavior.

Maslows hierarchy of needs outlines a five-tier pyramid of deficiency and being needs. Once deficiency needs the first tier are met, people strive for self-fulfillment and personal growth, behaviors that encompass the fifth tier of the pyramid.

Depression is an interesting example of behavior at the intersection of social sciences and biology. Behavioral theory argues depression results from peoples interactions with the environment and psychodynamic theory states it stems from inwardly-directed anger or loss of self-esteem.

Conversely, Mizumori explained depression from a behavioral switch, or flexible decision-making standpoint.

Researchers in human centered design and engineering (HCDE) are attempting to design technologies that can support or prompt changes in peoples behaviors.

A lot of the research projects we explore are real-world-problem driven, Gary Hsieh, an associate professor in HCDE, said. How do we encourage users to eat healthier or exercise more? These are health-related problems aligned to behavior-related problems.

By studying the needs and values of certain groups, researchers like Hsieh are able to design technologies that encourage people to communicate and interact in welfare-improving ways. In a growing age of data, engineers and scientists are able to learn about people from social networks.

Data allows us to study people in ways that we could not before, Hsieh said. It ties in with the types of interventions and applications that we can build.

Human behavior presents unknown complexities that arise from cultural, social, internal, environmental, and biological factors. Being able to integrate all those is a challenge that many will be addressing for generations to follow.

Reach reporter Vidhi Singh at science@dailyuw.com. Twitter: @vidhisvida

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Human behavior at the intersection of many sciences - Dailyuw