Hormone Replacement Therapy Doctor | Genemedics

Genemedics Health Institute is the national leader in bioidentical hormone replacement therapy for men (BHRT for men) and bioidentical hormone replacement therapy for women (BHRT for women). Led by nationally renowned Dr. George Shanlikian, M.D., Genemedics Health Institutes physician experts specialize in natural bioidentical hormone replacement therapy (BHRT), personalized nutrition programs, nutritional supplements, and fitness for both men and women.

Genemedics bioidentical hormone programs are customized for each individual to alleviate symptoms associated with:

Bioidentical hormones that may need to be balanced include:

All of our physicians are board-certified in Anti-Aging and Regenerative Medicine through the American Academy of Anti-Aging Medicine (A4M). Our expert physicians have passed written and oral exams and are among the most knowledgeable physicians in the field of anti-aging and natural hormone replacement therapy. Our natural hormone replacement therapy doctors have also completed advanced fellowships in Anti-Aging and Regenerative Medicine, completing hundreds of hours of additional training in anti-aging medicine and bioidentical hormone replacement therapy.

Genemedics' physician-supervised health program consists of natural bioidentical hormone replacement therapy, along with a nutrition plan, nutritional supplement regimen, and exercise program customized to help you reach your health and fitness goals.We have seen astonishing results in the lives of our patients, who are healthier, happier, and have dramatically improved quality of life. We incorporate functional testing such as body fat assessment, fitness testing, and stretch testing to gauge patient progress. We pay close attention to detail and routinely follow up with complete lab panels to make sure you have obtained and maintain hormone balance, along with optimal health and wellness. Our comprehensive natural bioidentical hormone replacement therapy programs, combined with proper nutrition and exercise, will return you to the optimal physical, sexual, and emotional health you experienced in your twenties and thirties. Contact us today and get started on the path to a younger, healthier you!

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Hormone Replacement Therapy Doctor | Genemedics

Parkinson's Disease Dementia | Signs, Symptoms, & Diagnosis

About Parkinson's disease dementia

The brain changes caused by Parkinson's disease begin in a region that plays a key role in movement. As Parkinson's brain changes gradually spread, they often begin to affect mental functions, including memory and the ability to pay attention, make sound judgments and plan the steps needed to complete a task.

The key brain changes linked to Parkinson's disease and Parkinson's disease dementia are abnormal microscopic deposits composed chiefly of alpha-synuclein, a protein that's found widely in the brain but whose normal function isn't yet known. The deposits are called "Lewy bodies".

Lewy bodies are also found in several other brain disorders, including dementia with Lewy bodies (DLB). Evidence suggests that dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia may be linked to the same underlying abnormalities in brain processing of alpha-synuclein.

Another complicating factor is that many people with both dementia with Lewy bodies and Parkinson's disease dementia also have plaques and tangles hallmark brain changes linked to Alzheimer's disease.

Parkinson's disease is a fairly common neurological disorder in older adults, estimated to affect nearly 2 percent of those older than age 65. The National Parkinson Foundation estimates that 1 million Americans have Parkinson's disease. It is estimated that 50 to 80 percent of those with Parkinson's disease eventually experience Parkinson's disease dementia. Sign up for our enews to receive updates about Alzheimers and dementia care and research.

Learn more: Dementia with Lewy Bodies, Mixed Dementia

What percentage of people with Parkinson's develop dementia?

An estimated 50 to 80 percent of those with Parkinson's eventually experience dementia as their disease progresses. The average time from onset of Parkinson's to developing dementia is about 10 years.

Parkinson's disease dementia is a decline in thinking and reasoning that develops in someone diagnosed with Parkinson's disease at least a year earlier. Common symptoms include:

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As with other types of dementia there is no single test or any combination of tests that conclusively determines that a person has Parkinson's disease dementia.

Many experts now believe that Parkinson's disease dementia and dementia with Lewy bodies are two different expressions of the same underlying problems with brain processing of the protein alpha-synuclein. But most experts recommend continuing to diagnose dementia with Lewy bodies and Parkinson's dementia as separate disorders.

Guidelines for diagnosing Parkinson's disease dementia and dementia with Lewy bodies are:

Brain Imaging

Since individuals with Parkinson's are at high risk for dementia as their disease progresses, doctors monitor those with Parkinson's closely for signs of thinking changes. When someone with Parkinson's develops thinking changes, doctors often order magnetic resonance imaging (MRI) of the brain to rule out tumors, structural changes and evidence for vascular disease.

Certain factors at the time of Parkinson's diagnosis may increase future dementia risk, including older age, greater severity of motor symptoms, and having mild cognitive impairment (MCI).

Additional risk factors may include:

There are no treatments to slow or stop the brain cell damage caused by Parkinson's disease dementia. Current strategies focus on helping symptoms.

If your treatment plan includes medications, it's important to work closely with your physician to identify the drugs that work best for you and the most effective doses. Treatment considerations involving medications include the following issues:

Find a clinical trial

More than 100 research studies pertaining to Alzheimer's and other dementias are underway. Alzheimer's Association TrialMatch lets you search these trials quickly and easily. Find a trial.

Like other types of dementia that destroy brain cells, Parkinson's disease and Parkinson's disease dementia get worse over time and speed of progression can vary.

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Parkinson's Disease Dementia | Signs, Symptoms, & Diagnosis

Stem Cells: Get Facts on Definition, Types, and Research

Stem cell facts

Stem cells are cells that have the potential to develop into many different or specialized cell types. Stem cells can be thought of as primitive, "unspecialized" cells that are able to divide and become specialized cells of the body such as liver cells, muscle cells, blood cells, and other cells with specific functions. Stem cells are referred to as "undifferentiated" cells because they have not yet committed to a developmental path that will form a specific tissue or organ. The process of changing into a specific cell type is known as differentiation. In some areas of the body, stem cells divide regularly to renew and repair the existing tissue. The bone marrow and gastrointestinal tract are examples of areas in which stem cells function to renew and repair tissue.

The best and most readily understood example of a stem cell in humans is that of the fertilized egg, or zygote. A zygote is a single cell that is formed by the union of a sperm and ovum. The sperm and the ovum each carry half of the genetic material required to form a new individual. Once that single cell or zygote starts dividing, it is known as an embryo. One cell becomes two, two become four, four become eight, eight become sixteen, and so on, doubling rapidly until it ultimately grows into an entire sophisticated organism composed of many different kinds of specialized cells. That organism, a person, is an immensely complicated structure consisting of many, many, billions of cells with functions as diverse as those of your eyes, your heart, your immune system, the color of your skin, your brain, etc. All of the specialized cells that make up these body systems are descendants of the original zygote, a stem cell with the potential to ultimately develop into all kinds of body cells. The cells of a zygote are totipotent, meaning that they have the capacity to develop into any type of cell in the body.

The process by which stem cells commit to become differentiated, or specialized, cells is complex and involves the regulation of gene expression. Research is ongoing to further understand the molecular events and controls necessary for stem cells to become specialized cell types.

Medically Reviewed by a Doctor on 6/3/2015

Stem Cells - Experience Question: Please describe your experience with stem cells.

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Medical Author:

Melissa Conrad Stppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

Medical Editor:

Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Stem Cells: One of the human body's master cells, with the ability to grow into any one of the body's more than 200 cell types.

All stem cells are unspecialized (undifferentiated) cells that are characteristically of the same family type (lineage). They retain the ability to divide throughout life and give rise to cells that can become highly specialized and take the place of cells that die or are lost.

Stem cells contribute to the body's ability to renew and repair its tissues. Unlike mature cells, which are permanently committed to their fate, stem cells can both renew themselves as well as create new cells of whatever tissue they belong to (and other tissues).

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Stem Cells: Get Facts on Definition, Types, and Research

Menopause: MedlinePlus Medical Encyclopedia

Treatment may include lifestyle changes or hormone therapy. Treatment depends on many factors such as:

HORMONE THERAPY

Hormone therapy may help if you have severe hot flashes, night sweats, mood issues, or vaginal dryness. Hormone therapy is treatment with estrogen and, sometimes, progesterone.

Talk to your doctor about the benefits and risks of hormone therapy. Your doctor should be aware of your entire medical and family history before prescribing hormone therapy (HT).

Several major studies have questioned the health benefits and risks of hormone therapy, including the risk of developing breast cancer, heart attacks, strokes, and blood clots.

Current guidelines support the use of HT for the treatment of hot flashes. Specific recommendations:

To reduce the risks of estrogen therapy, your doctor may recommend:

Women who still have a uterus (that is, have not had surgery to remove it for any reason) should take estrogen combined with progesterone to prevent cancer of the lining of the uterus (endometrial cancer).

ALTERNATIVES TO HORMONE THERAPY

There are other medicines that can help with mood swings, hot flashes, and other symptoms. These include:

DIET AND LIFESTYLE CHANGES

Lifestyle steps you can take to reduce menopause symptoms include:

Diet changes:

Exercise and relaxation techniques:

Other tips:

More here:
Menopause: MedlinePlus Medical Encyclopedia

Hypogonadism | Disorders | Knowledge Base

Hypogonadism can occur for a number of reasons. Certain men have hypogonadism since birth while others may develop this condition later in life. Two types of hypogonadism are:

Primary hypogonadism (testicular failure) - Low serum testosterone levels and gonadotropins (FSH, LH) above the normal range.

Hypogonadotropic hypogonadism - Idiopathic gonadotropin or LHRH deficiency or pituitary - hypothalamic injury from tumors, trauma, or radiation.

Characterized by low serum testosterone levels, but with gonadotropins in the normal or low range. Men develop testicular suppression with decreased libido, impotence, decreased ejaculate volume, loss of body and facial hair, weakness, fatigue and often anemia. On testing, blood levels of testosterone are low and should be replaced. In the United States, testosterone may begiven as a bi-weekly intramuscular injection, a patch form, or a gel preparation. In other countries, oral preparations of testosterone are available.

Women develop ovarian suppression with irregular periods or absence of periods (amenorrhea), infertility, decreased libido, decreased vaginal secretions, breast atrophy, and osteoporosis. Blood levels of estradiol are low. Estrogen should be replaced and can be given orally as Premarin or Estrace, or can be given as a patch applied twice weekly. Women taking estrogen also need to take progesterone replacement (unless they have undergone a hysterectomy). Annual pap smears and mammograms are mandatory.

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If you are a nurse or medical professional, register for PNA CEU Membership and earn CEU credits to learn about the symptoms, diagnosis and treatment options for patients with pituitary disorders. Help PNA reduce the time it takes for patients to get an accurate diagnosis.

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Hypogonadism | Disorders | Knowledge Base

Psoriasis: MedlinePlus Medical Encyclopedia

Menter A, Gottlieb A, Feldman SR, Voorhees ASV, Leonardi CL, Gordon KB, et al. Guidelines for the management of psoriasis and psoriatic arthritis. Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.J Am Acad Dermatol

Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB, et al. American Academy of Dermatology guidelines of care for the management of psoriasis and psoriatic arthritis. Section 3. Guidelines of care for the management and treatment of psoriasis with topical therapies.J Am Acad Dermatol

Menter A, Korman NJ, Elments CA, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis.Section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy.J Am Acad Dermatol. http://www.ncbi.nlm.nih.gov/pubmed/19811850

Psoriasis. Alvero R, Ferri FF, Fort GG, et al, eds. In:Ferri's Clinical Advisor 2015.

Stern RS. Psoralen and ultraviolet a light therapy for psoriasis.N Engl J Med.www.ncbi.nlm.nih.gov/pubmed/17699818

Weigle N, McBane S. Psoriasis.Am Fam Physician.

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Psoriasis: MedlinePlus Medical Encyclopedia

Rheumatoid Arthritis Center – Pompano Beach, FL

2

Richard S. Glick Richard S Glick MD 6405 N Federal Hwy Ste 105 Fort Lauderdale, FL 33308 (954) 772-3660

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Trumane J. Ropos Ropos Rheumatology 6405 N Federal Hwy Ste 103 Fort Lauderdale, FL 33308 (954) 358-1325

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Aviva C. Hopkins Holy Cross Physician Partners 1000 NE 56th St Fort Lauderdale, FL 33334 (954) 351-7800

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Jihan M. Saba Holy Cross Physician Partners 1000 NE 56th St Fort Lauderdale, FL 33334 (954) 351-7800

6

Richard K. Mastrole Holy Cross Physician Partners 1900 E Commercial Blvd Ste 101 Fort Lauderdale, FL 33308 (954) 351-5838

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Christine N. Savage University Of Miami Medical Gro 1475 NW 12th Ave Fl 1 Miami, FL 33136 (305) 243-7545

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Amarie Negron-Rodriguez Cria Center For Rheumatology & Immunology 2900 W Cypress Creek Rd Ste 11 Fort Lauderdale, FL 33309 (954) 229-7030

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Yvonne R. Smallwood-Sherrer Cria Center For Rheumatology & Immunology 2900 W Cypress Creek Rd Ste 11 Fort Lauderdale, FL 33309 (954) 229-7030

10

Elliot S. Cohen Elliot S Cohen MD Inc 1801 W Hillsboro Blvd Deerfield Beach, FL 33442 (954) 429-9050

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Elias Halpert West Broward Rheumatlgy Asscs 7431 N University Dr Ste 300 Tamarac, FL 33321 (954) 724-5560

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Kevin E. Stone West Broward Rheumatlgy Asscs 7431 N University Dr Ste 300 Tamarac, FL 33321 (954) 724-5560

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Steven C. Kimmel West Broward Rheumatlgy Asscs 7431 N University Dr Ste 300 Tamarac, FL 33321 (954) 724-5560

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Alan R. Alberts West Broward Rheumatlgy Asscs 7431 N University Dr Ste 300 Tamarac, FL 33321 (954) 724-5560

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Barry K. Waters Florida Institute Of Health 3100 Coral Hills Dr Ste 302 Coral Springs, FL 33065 (954) 341-5034

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Shawn B. Baca Rheumatology Associates South Florida 5162 Linton Blvd Ste 101 Delray Beach, FL 33484 (561) 498-1114

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Korey R. Ullrich Rheumatology Associates South Florida 5162 Linton Blvd Ste 101 Delray Beach, FL 33484 (561) 498-1114

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Joseph Z. Forstot Rheumatology Associates South Florida 1050 NW 15th St Ste 212A Boca Raton, FL 33486 (561) 368-5611

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Arnold S. Falchook Arnold S Falchook MD 1050 NW 15th St Ste 106A Boca Raton, FL 33486 (561) 362-1166

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Margaret R. Wilkes Rheumatology Associates South Florida 5162 Linton Blvd Ste 101 Delray Beach, FL 33484 (561) 498-1114

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Ira Pardo Rheumatology Associates South Florida 5162 Linton Blvd Ste 101 Delray Beach, FL 33484 (561) 498-1114

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David Alboukrek Rheumatology Associates South Florida 5162 Linton Blvd Ste 101 Delray Beach, FL 33484 (561) 498-1114

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Lori F. Soberal Rheumatology Associates South Florida 5162 Linton Blvd Ste 101 Delray Beach, FL 33484 (561) 498-1114

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William A. Sunshine William A Sunshine MD 660 Glades Rd Ste 306 Boca Raton, FL 33431 (561) 862-0401

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Steven L. Feldman Florida Institute Of Health 7351 W Oakland Park Blvd Ste 104 Lauderhill, FL 33319 (954) 741-5800

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David Makover David Makover MD 2900 N Military Trl Ste 244 Boca Raton, FL 33431 (561) 367-0078

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Prabodh K. Kapila Prabodh K Kapila MD 201 NW 82nd Ave Ste 303 Plantation, FL 33324 (954) 370-1153

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Julia Savloff Integral Rheumatology & Immunology Specialists 140 SW 84th Ave Ste B Plantation, FL 33324 (954) 476-2338

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Lilliam Ayala Garcia Integral Rheumatology & Immunology Specialists 140 SW 84th Ave Ste B Plantation, FL 33324 (954) 476-2338

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Guillermo J. Valenzuela Integral Rheumatology & Immunology Specialists 140 SW 84th Ave Ste B Plantation, FL 33324 (954) 476-2338

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Steven I. Goodman Arthritis Associates South 5130 Linton Blvd Ste F1 Delray Beach, FL 33484 (561) 483-1100

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Michael G. Indelicato Arthritis Associates South 5130 Linton Blvd Ste F1 Delray Beach, FL 33484 (561) 483-1100

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Marypat L. Clements Arthritis Associates South 5130 Linton Blvd Ste F1 Delray Beach, FL 33484 (561) 483-1100

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Philippe A. Saxe Arthritis Associates South 5130 Linton Blvd Ste F1 Delray Beach, FL 33484 (561) 483-1100

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Phillip S. Kallen Arthritis Associates South 5130 Linton Blvd Ste F1 Delray Beach, FL 33484 (561) 483-1100

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Brett R. Hutton Advanced Rheumatology Center 15300 Jog Rd Ste 101 Delray Beach, FL 33446 (561) 819-3100

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Evan J. Abramsky Advanced Rheumatology Center 15300 Jog Rd Ste 101 Delray Beach, FL 33446 (561) 819-3100

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Marc J. Hirsh Advanced Rheumatology Center 15300 Jog Rd Ste 101 Delray Beach, FL 33446 (561) 819-3100

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Alain Alvarez Advanced Rheumatology Center 15300 Jog Rd Ste 101 Delray Beach, FL 33446 (561) 819-3100

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Hope Starkman Ocean Ridge Arthritis Associates 1880 N Congress Ave Ste 320 Boynton Beach, FL 33426 (561) 736-9699

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Yesenia D. Santiago Kahn & Raskin MDs 1 SW 129th Ave Ste 401 FL 4 Pembroke Pines, FL 33027 (954) 450-8980

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Lynette M. Weitman Nicholson Kahn & Raskin MDs 1 SW 129th Ave Ste 401 FL 4 Pembroke Pines, FL 33027 (954) 450-8980

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Wayne G. Riskin Kahn & Raskin MDs 1 SW 129th Ave Ste 401 FL 4 Pembroke Pines, FL 33027 (954) 450-8980

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Michelle J. Parlo Kahn & Raskin MDs 1 SW 129th Ave Ste 401 FL 4 Pembroke Pines, FL 33027 (954)
450-8980

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Charles B. Kahn Kahn & Raskin MDs 1 SW 129th Ave Ste 401 FL 4 Pembroke Pines, FL 33027 (954) 450-8980

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Eileen J. Ginsburg Boynton Beach Arthritis Center 13550 Jog Rd Ste 204 Delray Beach, FL 33446 (561) 737-1947

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Rosa T. Artola Benjamin L Lechner MD 2100 E Hallandale Beach Blvd Ste 302 Hallandale Beach, FL 33009 (954) 456-8900

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Eva M. Cappiello Boynton Beach Arthritis Center 13550 Jog Rd Ste 204 Delray Beach, FL 33446 (561) 737-1947

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Richard A. Cappiello Boynton Beach Arthritis Center 13550 Jog Rd Ste 204 Delray Beach, FL 33446 (561) 737-1947

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Benjamin L. Lechner Benjamin L Lechner MD 2100 E Hallandale Beach Blvd Ste 302 Hallandale Beach, FL 33009 (954) 456-8900

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Paul Sweeney Chain Medical 2150 W 68th St Ste 200 Hialeah, FL 33016 (305) 828-4300

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Rheumatoid Arthritis Center - Pompano Beach, FL

Rheumatoid Arthritis Symptoms, Treatment, Diet, Medication

Medical Editor:

Catherine Burt Driver, MD, is board certified in internal medicine and rheumatology by the American Board of Internal Medicine. Dr. Driver is a member of the American College of Rheumatology. She currently is in active practice in the field of rheumatology in Mission Viejo, Calif., where she is a partner in Mission Internal Medical Group.

Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints. Autoimmune diseases are illnesses that occur when the body's tissues are mistakenly attacked by their own immune system. The immune system contains a complex organization of cells and antibodies designed normally to "seek and destroy" invaders of the body, particularly infections. Patients with autoimmune diseases have antibodies and immune cells in their blood that target their own body tissues, where they can be associated with inflammation. While inflammation of the tissue around the joints and inflammatory arthritis are characteristic features of rheumatoid arthritis, the disease can also cause inflammation and injury in other organs in the body. Because it can affect multiple other organs of the body, rheumatoid arthritis is referred to as a systemic illness and is sometimes called rheumatoid disease. Rheumatoid arthritis that begins in people under 16 years of age is referred to as juvenile idiopathic arthritis (formerly juvenile rheumatoid arthritis).

While rheumatoid arthritis is a chronic illness, meaning it can last for years, patients may experience long periods without symptoms. However, rheumatoid arthritis is typically a progressive illness that has the potential to cause significant joint destruction and functional disability.

A joint is where two bones meet to allow movement of body parts. Arthritis means joint inflammation. The joint inflammation of rheumatoid arthritis causes swelling, pain, stiffness, and redness in the joints. The inflammation of rheumatoid disease can also occur in tissues around the joints, such as the tendons, ligaments, and muscles.

In some people with rheumatoid arthritis, chronic inflammation leads to the destruction of the cartilage, bone, and ligaments, causing deformity of the joints. Damage to the joints can occur early in the disease and be progressive. Moreover, studies have shown that the progressive damage to the joints does not necessarily correlate with the degree of pain, stiffness, or swelling present in the joints.

Rheumatoid arthritis is a common rheumatic disease, affecting approximately 1.3 million people in the United States, according to current census data. The disease is three times more common in women as in men. It afflicts people of all races equally. The disease can begin at any age and even affects children (juvenile idiopathic arthritis), but it most often starts after 40 years of age and before 60 years of age. Though uncommon, in some families, multiple members can be affected, suggesting a genetic basis for the disorder.

Medically Reviewed by a Doctor on 6/15/2015

Rheumatoid Arthritis - Early Symptoms Question: What were your symptoms at the onset of your rheumatoid arthritis?

Rheumatoid Arthritis - Treatments Question: What treatments have been effective for your rheumatoid arthritis?

Rheumatoid Arthritis - Experience Question: Please describe your experience with rheumatoid arthritis.

Rheumatoid Arthritis - Prognosis Question: What's the prognosis for your rheumatoid arthritis?

Rheumatoid Arthritis - Diet Question: Discuss the diet or other lifestyle changes you've made to relieve symptoms of RA.

Rheumatoid Arthritis - Diagnosis Question: What led to your rheumatoid arthritis diagnosis?

Medical Author:

Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.

Medical Editor:

Melissa Conrad Stppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.

While early symptoms of rheumatoid arthritis can actually be mimicked by other diseases, the symptoms are very characteristic of rheumatoid disease. Rheumatoid arthritis symptoms and signs include the following:

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Rheumatoid Arthritis Symptoms, Treatment, Diet, Medication

Dementia – Cognitive Impairment Disorder Symptoms & Signs …

What is Dementia?

Dementia is a decline in cognitive function. It may affect memory, thinking, language, judgment, and behavior. To be considered dementia, mental impairment must affect at least two brain functions. It may also cause personality changes.

Dementia is not a disease. It may be caused by a variety of illnesses or injuries. Mental impairment may range from mild to severe. Some dementias are progressive, which means they get worse over time. Some dementias are treatable or even reversible. Some experts restrict the term dementia to irreversible mental deterioration.

Dementia can be caused by degeneration of neurons (brain cells), or by disturbances in other body systems that affect how neurons function.

Several conditions can cause dementia, including diseases of the brain. The most common such causes are Alzheimers disease and vascular dementia.

Neurodegenerativemeans that neurons gradually degenerate (cease to function or function inappropriately and eventually die). This impacts the neuron-to-neuron connections, calledsynapses, which arehow messages are passed along in your brain. This disconnect can result in a range of dysfunction.

Some of the more common causes of dementia include:

Another cause is frontotemporal lobar degeneration, which is a blanket term for a range of conditions that cause damage to the frontal and temporal lobes of the brain. They include:

Dementia may also be caused by

Some of these dementias may be reversible. This is one of the many reasons why it is important to see your doctor and get a medical workup as soon as symptoms develop.

Its absolutely normal to forget things once in a while. Memory loss by itself does not mean you have dementia. However, there is a difference between occasional forgetfulness and forgetfulness that is cause for serious concern.

Potential red flags for dementia include:

Seek medical attention if you experience any of the above.

Getting lost in familiar settings (driving to the supermarket, for example), is often one of the first signs of dementia.

The Merck Manual states that approximately five percent of people aged 65 to 74 years and 40 percent of people older than 85 years have some form of dementia.

The number of people diagnosed with and/or living with dementia is increasing. This is at least in part due to increasing life expectancy. By 2030, the size of the population 65 years of age and older in the U.S. will have increased from 37 million people (in 2006) to an estimated 71.5 million, according to the U.S. Census Bureau.

Scientists all over the world are working hard to gain a better understanding of the many different aspects of dementia. This might help to develop preventive measures (such as a vaccine), improved early detection diagnostic tools, better and longer-lasting treatments, and even cures.

For example, a vaccine known as a bapineuzumab jab is currently in its final phase of testing.Though it cannot cure dementia or related disorders, this vaccine has been shown to prevent, and in some cases reverse, the buildup of amyloid plaques in the brain.Amyloid plaqueswhich are the hallmark of Alzheimers diseaseare dense, mostly insoluble (not dissolvable) clumps of protein fragments that deposit a highly damaging gunky substanceoutside and aroundthe brains nerve cells.

Scientists are also investigating genetic factors, various neurotransmitters, the role of inflammation, factors that influence programmed cell death in the brain, the roles oftau (a protein found in neurons of the central nervous system), and the possible roles of oxidative stress (i.e., chemical reactions that can damage proteins, DNA, and lipids/fats inside cells) in the development of dementia. Such research can help doctors and scientists better understand what causes dementia, and in turn, how best to treat and possibly prevent the disorder.

There is also increasing evidence that lifestyle factors, such as getting regular exercise and maintaining social connections, may be effective ways to decrease the risk of developing dementia.

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Dementia - Cognitive Impairment Disorder Symptoms & Signs ...

Spinocerebellar Ataxia – Genetic Clumsiness Disorders

Updated December 04, 2014.

When people discuss spinal cerebellar ataxia (SCA), they are actually referring to a group of neurodegenerative disorders that cause progressive clumsiness. There are more than 35 different types of spinal cerebellar ataxias, each caused by a different genetic mutation. Furthermore, new forms continue to be discovered.

Despite there being so many different variations, SCA is actually pretty rare. Even so, it is one of the most common causes of genetic ataxia.

Even among people with no family history who develop ataxia for no other clear reason, a new SCA mutation can be found about 20 percent of the time.

What Causes SCA?

SCA is due to a genetic mutation. Many types are due to so-called expansion mutations, in which several nucleotides (usually cytosine, adenosine, and guanine) repeat more than is found in healthy people. In the common form involving three nucleotides repeating, this is called a trinucleotide repeat. The result of that repetition is that a mutated form of protein is expressed, leading to disease symptoms.

Spinocerebellar ataxia is usually inherited in an autosomal dominant fashion, meaning that if one of the parents has the disorder, there is about a 50 percent chance that a child will have the disease as well.

As the name spinocerebellar ataxia suggests, the disease afflicts the cerebellum and more. The brainstem can also waste away (atrophy), especially in SCA types 1, 2, and 7. The regions of the atrophy often control eye movements, leading to abnormal findings when a neurologist performs their physical exam.

What Is the Prognosis in Spinal Cerebellar Atrophy?

Spinocerebellar ataxias due to repeat expansion mutations usually become sick in middle age. In addition to ataxia, other neurological findings are often present depending on the variant of SCA. In general, the longer the repeat is, the younger the patient will be when the symptoms come on, and the more rapid the disease progression.

In general, SCA type 1 is more aggressive than types 2 or 3, and type 6 is the least aggressive SCA due to a trinucleotide repeat. We dont have much information on other types of spinocerebellar ataxias, but most people will require a wheelchair 10 to 15 years after the symptoms come on. While most forms of SCA shorten the lifespan, this is not always the case.

How Is Spinocerebellar Atrophy Treated?

There is no cure for SCA. Medications such as zolpidem or varenicline have been suggested to help ataxia in SCA type 2 and 3 respectively.

SCA1

SCA1 causes about 3 to 16 percent of autosomal dominant cerebellar ataxias. In addition to ataxia, SCA1 is associated with difficulty speaking and swallowing. Increased reflexes are also common. Some patients also develop muscle wasting.

The mutation of SCA1 is a trinucleotide repeat in a region called ataxin 1. The mutated form of ataxin 1 clumps together in cells, and may change how nerve cells translate their own genetic codes. This is especially true in cells of the cerebellum.

SCA2

About 6 to 18 percent of people with spinocerebellar ataxia have SCA2. SCA 2 also causes coordination problems, but also causes slow eye movements. In severe cases, SCA 2 can cause developmental delay, seizures, and difficulty swallowing even in infancy.

SCA2 is caused by another trinucleotide repeat, this time encoding a protein called ataxin 2. Wheras SCA1 affects the nucleus of the cell and DNA, SCA2 seems to affect RNA and collects outside the nucleus.

SCA2 demonstrates how different people can suffer different symptoms even if they have the same mutation. An Italian family with SCA2 has suffered mental deterioration, and families from Tunesia have suffered chorea and dystonia.

SCA3

SCA3, better known as Machado-Joseph disease, is the most common autosomal dominant SCA, making up between 21 to 23 percent of SCA in the United States. In addition to ataxia, patients with Machado-Joseph have slow eye movements and difficulty swallowing. Cognitive impairments may also occur, as can dysautonomia. On the neurologists exam, patients with SCA3 may have a mixture of upper and lower motor neuron findings suggestive of amyotrophic lateral sclerosis.

SCA 4 and 5

These forms are less common, and are not due to trinucleotide repeats. SCA4 can have a peripheral neuropathy, but thats true of most spinocerebellar ataxias. SCA5 has almost no other symptoms than ataxia. SCA5 tends to be mild and progress slowly. Interestingly, the original mutation seems to have descended from the paternal grandparents of Abraham Lincoln.

SCA6

SCA6 accounts for 15 to 17 percent of SCA. The mutation is in a gene also associated with episodic ataxia and some forms of migraine. In addition to ataxia, an abnormal eye movement known as nystagmus may appear on the neurological examination.

SCA7

SCA7 only comprises 2 to 5 percent of autosomal dominant spinocerbellar ataxias. The symptoms depend on the age of the patient and the size of the repeat. Vision loss is sometimes associated with SCA7. In adults, this vision loss may come on before the ataxia. If the trinucleotide repeat is long, vision loss can actually come on first In childhood, seizures and heart disease come on with ataxia and vision loss.

Because the rest of the spinocerebellar ataxias are so rare, Im not going to discuss them in any detail. Most of the time, the symptoms are difficult to distinguish from other SCAs that weve already covered, but the genetic mutations are different.

For example, SCA8 is looks very much like other SCA, but is unusual in that rather than things getting worse with larger trinucleotide repeats, its only problem when there are 80 to 250 repeats. More or less doesnt seem to create a problem. SCA10 is a pentanucleotide repeat rather than a trinucleotide repeat. Some of these disorders, such as SCA25, have only been described in one family.

Other Spinocerebellar Ataxias

Although spinocerebellar ataxia is uncommon, it important for neurologists and patients to consider this diagnosis if there is a family history of clumsiness. A diagnosis of SCA may have important implications not just for the person immediately affected, but for their entire family as well.

Sources:

Geschwind DH, Perlman S, Figueroa CP, et al. The prevalence and wide clinical spectrum of the spinocerebellar ataxia type 2 trinucleotide repeat in patients with autosomal dominant cerebellar ataxia. Am J Hum Genet 1997; 60:842.

Moseley ML, Benzow KA, Schut LJ, et al. Incidence of dominant spinocerebellar and Friedreich triplet repeats among 361 ataxia families. Neurology 1998; 51:1666.

Ranum LP, Lundgren JK, Schut LJ, et al. Spinocerebellar ataxia type 1 and Machado-Joseph disease: incidence of CAG expansions among adult-onset ataxia patients from 311 families with dominant, recessive, or sporadic ataxia. Am J Hum Genet 1995; 57:603.

Storey E, du Sart D, Shaw JH, et al. Frequency of spinocerebellar ataxia types 1, 2, 3, 6, and 7 in Australian patients with spinocerebellar ataxia. Am J Med Genet 2000; 95:351.

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Spinocerebellar Ataxia - Genetic Clumsiness Disorders

Autism spectrum disorder – Mayo Clinic

Autism spectrum disorder is a serious neurodevelopmental disorder that impairs a child's ability to communicate and interact with others. It also includes restricted repetitive behaviors, interests and activities. These issues cause significant impairment in social, occupational and other areas of functioning.

Autism spectrum disorder (ASD) is now defined by the American Psychiatric Association's Diagnosis and Statistical Manual of Mental Disorders (DSM-5) as a single disorder that includes disorders that were previously considered separate autism, Asperger's syndrome, childhood disintegrative disorder and pervasive developmental disorder not otherwise specified.

The term "spectrum" in autism spectrum disorder refers to the wide range of symptoms and severity. Although the term "Asperger's syndrome" is no longer in the DSM, some people still use the term, which is generally thought to be at the mild end of autism spectrum disorder.

The number of children diagnosed with autism spectrum disorder is rising. It's not clear whether this is due to better detection and reporting or a real increase in the number of cases, or both.

While there is no cure for autism spectrum disorder, intensive, early treatment can make a big difference in the lives of many children.

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Autism spectrum disorder - Mayo Clinic

Causes of secondary hypogonadism in males UpToDate

INTRODUCTION

Hypogonadism in a male refers to a decrease in either or both of the two major functions of the testes: sperm production and/or testosterone production (see "Male reproductive physiology"). These abnormalities can result from disease of the testes (primary hypogonadism) or disease of the pituitary or hypothalamus (secondary hypogonadism). The distinction between these disorders is made by measurement of the serum concentrations of luteinizing hormone (LH) and follicle-stimulating hormone (FSH):

The patient has primary hypogonadism if his serum testosterone concentration and/or sperm count are low and/or his serum LH and FSH concentrations are high.

The patient has secondary hypogonadism if his serum testosterone concentration and/or the sperm count are low and/or his serum LH and FSH concentrations are inappropriately normal or low, which would be inappropriate if gonadotroph cell function were normal.

Secondary hypogonadism differs from primary hypogonadism in two characteristics:

Secondary hypogonadism is usually associated with similar decreases in sperm and testosterone production. This occurs because the reduction in LH secretion results in a decrease in testicular testosterone production and, therefore, in intratesticular testosterone, which is the principal hormonal stimulus to sperm production. In contrast, there is generally a greater fall in sperm production than in testosterone secretion in primary hypogonadism because the seminiferous tubules are damaged to a greater degree than the Leydig cells. Men with primary hypogonadism, therefore, might have normal serum testosterone and LH concentrations even when the number of ejaculated sperm is very low or zero and the FSH concentration is elevated.

Literature review current through: Aug 2015. | This topic last updated: Wed May 20 00:00:00 GMT 2015.

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Causes of secondary hypogonadism in males UpToDate

Andropause: When Guys Get 'The Change' | Lisa Turner

Note: Last month, I wrote a blog about foods for women in mid-life. After some -- heated -- commentary about my sexist approach to mid-life, I decided to cover the male aspect.

In 1944, researchers Carl Heller and Gordon Myers identified symptoms of what they termed "male climacteric," another word for menopause; these included loss of libido, depression, inability to concentrate, and sometimes hot flashes. The term "manopause" was later coined to describe the physical and emotional changes many men experience in their late 40s and early 50s. The popular media subsequently linked "manopause" to such 50-something male behaviors as buying a pricey sports car, changing careers, or hooking up with a younger woman.

While the phenomenon of a male menopause is debatable, the physical effect of reduced testosterone is very real. Testosterone is one of the primary male sex hormones, and it's crucial for the development of male reproductive tissues, building muscle, bone formation, normal sexual drive and stamina, and overall well-being. Starting around the age of 35, all men (and women) experience a gradual decline in the amount of testosterone their bodies produce; simultaneously, levels of sex-hormone-binding-globulin (SHBG) increase, further inhibiting testosterone.

By the time most men are in their 50s, testosterone levels are low enough to create a constellation of changes. This phenomenon is called "andropause," sometimes referred to as ADAM ("androgen deficiency in the aging male") or PADAM ("partial androgen deficiency in the aging male"). Some studies suggest that andropause is associated with increased risk of osteoporosis, heart disease, insulin resistance, and possibly Alzheimer's disease. More immediately noticeable effects of lower testosterone include weight gain, loss of libido, diminished mental acuity, reduced muscle bulk, depression, impaired memory and fatigue.

Not surprisingly, these changes dramatically affect a guy's emotional and spiritual well-being."Male menopause is a physical condition with psychological, interpersonal, social, and spiritual dimensions," says Jed Diamond, Ph.D., author of Male Menopause (Sourcebooks, 1998) and The Irritable Male Syndrome (Rodale Books, 2005). "Although this is a potent and multi-dimensional change of life, media often focus on the more superficial aspects of men leaving their older wives for a younger woman or changing careers." In Understanding Men's Passages (Ballantine Books, 1999), author Gail Sheehy says,"If menopause is the silent passage, male menopause is the unmentionable passage ... It strikes at the core of what it is to be a man ... his youthful sexual drive and performance."

Predictably enough, there's some controversy. Some say andropause is real, but "manopause" is a myth perpetuated by authors and companies to promote services and products designed to address the so-called male menopause. While few would argue that men lose testosterone as they age, it's an entirely different situation than menopause, some say, and has little to do with any perceived emotional or spiritual events. Unlike menopause, during which a woman's hormones decline suddenly and precipitously, the loss of testosterone is slow and gradual enough that most men don't notice the corresponding subtle changes. Say the authors of one study, "The extent to which an age-dependent decline in androgen levels leads to health problems that might affect or alter the quality of life remains under debate."

Whether andropause is a man's version of menopause replete with emotional, psychological and spiritual changes, or just a blip on the hormonal screen, may depend on your own circumstances and makeup. But if you're a guy (or you have a guy) who's experiencing some mid-life shakeups, some things you might consider:

Testosterone replacement therapy (also called TRT) can balance and replace testosterone levels and decrease the symptoms of andropause. Unlike estrogen or progesterone therapies, "pharmaceutical, prescription forms of testosterone, especially topical and pellet forms, are for the most part bio-identical," says Jennifer Landa, M.D., chief medical officer of BodyLogicMD in Orlando, Florida. "Even the injectable forms are very similar to bio identical." TRT can have side effects, and should be thoroughly discussed with your health care provider, especially if you're at risk for prostate cancer. Some natural supplements -- Tongkat ali, Tribulus terrestris, zinc, horny goat weed -- have shown promise too in easing symptoms of andropause.

Watch your weight. Testosterone can be converted to estrogen via an enzyme called aromatase. "Some men are genetically predisposed to more aromatase activity," says Landa, "but being heavy also has an impact, since aromatase is present to large degree in fat." And fat begets fat. "Lower testosterone as a result of aging means more muscle converts to fat," she says. "Then, having more fat means more testosterone is converted to estrogen. It's a really negative cycle of events."

Avoid estrogenic compounds. As testosterone levels naturally decrease with age, the ratio of testosterone to estrogen in a man's body falls. When men are exposed to additional sources of estrogen, it further upsets the balance of testosterone to estrogen. Endocrine disruptors and xenoestrogens from plastic food wraps, personal care products and conventionally raised meat and dairy are the most common sources. "These are just as important for men to avoid as for women, especially since they also increase the risk of prostate cancer," says Landa. To minimize exposure, choose organic, grass-fed or pastured animal products, avoid plastic food containers, and buy natural personal care products that are free of parabens and other chemicals.

Recognize the spiritual side. "During this stage, men have to look at all aspects of their lives, including the spiritual," says Diamond. "They may question old patterns and wonder, 'Now that I've done what I was supposed to do, what do I really want to do with my life while I still have time?'Many men have spent a lifetime on a career. Now they want to explore their calling, the deeper more spiritual aspect of what they do." Give yourself ample time and space to recognize these changes -- and be willing to go with deeper callings.

For more by Lisa Turner, click here.

For more on aging gracefully, click here.

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Andropause: When Guys Get 'The Change' | Lisa Turner

What Is Eczema | National Eczema Association

There is no cure for eczema, but, in most cases, it is manageable. The word eczema comes from a Greek word that means to effervesce or bubble or boil over. This website will help you answer the question What Is Eczema? and help you understand it. Its important to remember that many people have eczema. Over 30 million American may have it. There is no need to be embarrassed by your eczema. You are not alone. Atopic Dermatitis (which is often called eczema) is an itchy, red rash. It can appear all over the body. Many people have it on their elbows or behind their knees. Babies often have eczema on the face, especially the cheeks and chin. They can also have it on the scalp, trunk (chest and back), and outer arms and legs. Children and adults tend to have eczema on the neck, wrists, and ankles, and in areas that bend, like the inner elbow and knee. People with eczema are usually diagnosed with it when they are babies or young children. Eczema symptoms often become less severe as children grow into adults. For some people, eczema continues into adulthood. Less often, it can start in adulthood. The rash of eczema is different for each person. It may even look different or affect different parts of your body from time to time. It can be mild, moderate, or severe. Generally, people with eczema suffer from dry, sensitive skin. Eczema is also known for its intense itch. The itch may be so bad that you scratch your skin until it bleeds, which can make your rash even worse, leading to even more inflammation and itching. This is called the itch-scratch cycle.

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What Is Eczema | National Eczema Association

Eczema | BabyCenter

Definition of eczema in babies

Eczema (also called atopic dermatitis) is a skin rash that usually appears before age 5. In babies it tends to show up on the cheeks and scalp, but it may spread to the arms, legs, chest, or other parts of the body. After a child's first year, it's most likely to show up on the insides of the elbows, the backs of the knees, the wrists, and the ankles, but it can also appear elsewhere.

About 20 percent of babies and young children have eczema. It usually starts in infancy, with 65 percent of patients developing symptoms in the first year of life and 90 percent developing symptoms before age 5.

The rash might look like dry, thickened, scaly skin, or it might be made up of tiny red bumps that ooze or become infected if scratched. Scratching can also cause thickened, darkened, or scarred skin over time.

Eczema typically comes and goes. It isn't contagious, but because it's intensely itchy, it can be very uncomfortable, and scratching can be a problem. If untreated, the rash can be unsightly, so it may present a social challenge for a child, too.

Your doctor can diagnose eczema by examining your child's skin. He may send you to a dermatologist for confirmation and treatment.

There's no way to know ahead of time whether a child will outgrow eczema, but fortunately the condition usually becomes less severe with age. Many children outgrow eczema by age 2, and many others outgrow it by adulthood.

Dr P. Marazzi / Science Source

No one knows for sure what causes it, but the tendency to have eczema is often inherited. So your child is more likely to have it if you or a close family member has had eczema, asthma, or allergies.

Eczema is not an allergic reaction to a substance, but allergens or irritants in the environment (such as pollen or cigarette smoke) can trigger it. Less frequently, it can be triggered by allergens in your child's diet or in your diet if your child is breastfeeding.

The rash can also be aggravated by heat, irritants that come in contact with the skin (like wool or the chemicals in some soaps, fragrances, lotions, and detergents), changes in temperature, and dry skin. Stress can also trigger a flare-up of eczema.

Taking good care of your child's skin and avoiding triggers can help treat and prevent flare-ups.

Bathing and moisturizing

Talk with the doctor about how often to bathe your child. Many experts now believe that daily bathing can be helpful for children with eczema. Just don't make the water too warm, because very warm water dries out the skin faster than lukewarm water.

Use a mild soap or non-soap cleanser, and wash and shampoo your child at the end of the bath so he isn't sitting in soapy water. As soon as you get your child out of the tub, pat (don't rub) excess water from his skin with a soft towel or washcloth.

Then, while the skin is still damp, promptly apply a liberal amount of moisturizer or emollient an ointment, cream, or lotion that "seals in" the body's own moisture to your child's skin. Ointments and creams contain more emollient and less water than lotions and are usually best for children with eczema.

"I recommend emollients for children of all ages," says Michael Smith, an associate professor of medicine and pediatrics in the division of dermatology at Vanderbilt Medical Center in Nashville. He suggests testing the emollient for a short time to make sure it doesn't irritate your child's skin.

The most effective approach, according to Smith, is to hydrate and lubricate the skin at the same time by applying emollient to damp skin. The emollient won't improve the red, inflamed, itchy areas, but it will help restore the skin's invisible protective barrier. (This barrier makes up part of the normal outer layer of the skin and is impaired in kids with eczema.)

Allowing skin to breathe and stay cool

Dress your child in smooth natural fabrics, like cotton. Avoid wool and other scratchy materials, which can irritate very sensitive skin. Don't overheat your child by bundling him up more than necessary.

Soaps and cleansers

Switch to mild, fragrance-free soaps or non-soap cleansers and shampoos, or those made for sensitive skin. Use mild, fragrance-free detergent for washing clothes and bedding. Don't use fabric softeners.

Prevent scratching

Your child may try to get relief by scratching with his hands or by rubbing his face against the sheet during sleep. But scratching and rubbing can further irritate or inflame the skin and make matters much worse.

Use the softest sheets possible in the crib or bed, and keep your child's nails short. Put him to bed with cotton mittens or socks on his hands if he'll tolerate them.

If your child has a lot of trouble sleeping because of the itching, consult your doctor. He may suggest an antihistamine to help your child rest better.

Soothe flare-ups

During a flare-up, you can try applying cool compresses to the area several times a day, followed by a moisturizer.

A study published in the May 2009 issue of Pediatrics tested treatments on children with severe eczema. The kids ranged in age from 6 months to 17 years.

Researchers found that soaking for five to ten minutes twice a week in a diluted bleach bath was five times more effective at treating eczema than plain water (used by the placebo group). The improvement was so dramatic that the researchers stopped the study early to allow children in the placebo group to benefit from the method.

Amy Paller, senior author of the study and the Walter J. Hamlin professor and chair of the department of dermatology and professor of pediatrics at Northwestern University Feinberg School of Medicine, says that with their doctor's approval parents of children with moderate to severe eczema might want to try this method, especially if their child gets skin infections.

Paller recommends a scant two teaspoons of bleach per gallon of bathwater (or 1/2 cup per full tub) at least twice a week, taking these precautions: 1) Make sure your child doesn't drink the water. 2) Disperse the bleach in the water before putting your child in the tub (you don't want undiluted bleach to get on her skin).

Nashville pediatrician Smith agrees with Paller's approach. "It's safe and easy to do," he says. "It's basically like a freshly chlorinated swimming pool, which serves to kill germs in the pool. It is very useful for kids with recurrent skin infections related to eczema, but it has also been shown effective just to eliminate bacteria, making the eczema easier to treat."

Smith tells parents to use 1/3 to 1/2 cup for a full tub or 1 teaspoon per gallon. He also suggests rinsing off briefly afterward, to get rid of the bleach smell.

To avoid getting the bleach water in your child's eyes or mouth, Smith cautions not to use bleach on the face. Instead, he recommends a good barrier ointment such as petrolatum to protect the skin on the face from irritants such as saliva, food, and beverages.

For open, oozing areas on the face, he suggests over-the-counter antibiotic ointments such as bacitracin or a polymyxin/bacitracin combination. If these remedies don't work, it's time to get in touch with your child's doctor.

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Eczema | BabyCenter

Eczema Home Remedies – eMedicineHealth

Eczema (cont.) Eczema Prevention

Avoid, when possible, whatever triggers the rash.

See Self-Care at Home for other ideas on preventing eczema flares.

Atopic dermatitis usually spontaneously improves in most individuals after puberty. In a few unfortunate individuals, it becomes chronic, resulting in occasional flares often at times of very low humidity (such as wintertime with the heat on). It may also return much later in adulthood and may prove especially difficult to manage.

The role of psychological stress inducing flares of the dermatitis is poorly understood. There is no question that when the condition flares and sleep is inhibited by itching, one's normal ability to deal with emotional problems is diminished.

Repeated scratching of the rash can cause toughening of the skin. Small patches of the skin can become thickened and like leather. This condition is called lichen simplex chronicus. The scrotum and vulva are common areas for adult patients with a history of eczema to develop a persistent itch and develop such lichenification. (It would be very unusual for the penis itself to be involved in such cases and other diagnoses should be considered if it appears to be affected.)

Eczema causes skin sores and cracks that are susceptible to infection. These infections are usually very minor, but they do require treatment with antibiotics or they may become very severe. See a health-care professional if an infection is suspected.

Eczema may fade in adulthood, but people who have eczema tend to have lifelong problems with skin irritation and related problems.

Medically Reviewed by a Doctor on 5/12/2015

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Eczema Home Remedies - eMedicineHealth

Eczema – KidsHealth

It can be difficult to avoid all the triggers, or irritants, that may cause or worsen eczema flare-ups. In many people, the itchy patches of eczema usually appear where the elbow bends; on the backs of the knees, ankles, and wrists; and on the face, neck, and upper chest although any part of the body can be affected.

In an eczema flare-up, skin may feel hot and itchy at first. Then, if the person scratches, the skin may become red, inflamed, or blistered. Some people who have eczema scratch their skin so much it becomes almost leathery in texture. Others find that their skin becomes extremely dry and scaly. Even though many people have eczema, the symptoms can vary quite a bit from person to person.

If you think you have eczema, your best bet is to visit your doctor, who may refer you to a dermatologist (a doctor who specializes in treating skin). Diagnosing atopic eczema can be difficult because it may be confused with other skin conditions. For example, eczema can easily be confused with a skin condition called contact dermatitis, which happens when the skin comes in contact with an irritating substance, like the perfume in a certain detergent.

In addition to a physical examination, a doctor will take your medical history by asking about any concerns and symptoms you have, your past health, your family's health, any medications you're taking, any allergies you may have, and other issues.

Your doctor can also help identify things in your environment that may be contributing to your skin irritation. For example, if you started using a new shower gel or body lotion before the symptoms appeared, mention this to your doctor because a substance in the cream or lotion might be irritating your skin.

Emotional stress can also lead to eczema flare-ups, so your doctor might also ask you about any stress you're feeling at home, school, or work.

If you're diagnosed with eczema, your doctor might:

For some people with severe eczema, ultraviolet light therapy can help clear up the condition. Newer medications that change the way the skin's immune system reacts also may help.

If eczema doesn't respond to normal treatment, your doctor might do allergy testing to see if something else is triggering the condition, especially if you have asthma or seasonal allergies.

If you're tested for food allergies, you may be given certain foods (such as eggs, milk, soy, or nuts) and observed to see if the food causes an eczema flare-up. Food allergy testing also can be done by pricking the skin with an extract of the food substance and observing the reaction. But sometimes allergy testing can be misleading because someone may have an allergic reaction to a food that is not responsible for the eczema flare-up.

If you're tested for allergy to dyes or fragrances, a patch of the substance will be placed against your skin and you'll be monitored to see if skin irritation develops.

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Eczema - KidsHealth