How To Reach 100: Lifestyle Choices Vie With Genetics In Longevity

By Patricia Reaney

NEW YORK, June 7 (Reuters) - Genetics may be the best predictor of longevity, but lifestyle choices, including staying connected with family and friends, are key components to reaching the age of 100, according to a new poll released on Wednesday.

More than 80 percent of 100 men and women who have already hit the milestone said being socially active had helped them get there, and a similar number of baby boomers believe it will help them reach their 100th birthday.

"Scientifically we know that the formula, the best predictor, for how long someone will live has traditionally been how long their immediate relatives have lived, so we know genetics is a strong factor," said Dr. Rhonda Randall, chief medical officer of UnitedHealthcare, which conducted the survey.

"But we are seeing more and more that lifestyle choices -- physical exercise, diet, staying engaged, having a social purpose -- are becoming a stronger and stronger influence," she said in an interview.

Like their children and grandchildren, centenarians have turned to the Internet to stay connected.

About a quarter of 100-year-olds questioned in the telephone survey said they had access to the Web, double the number just a year ago. Of those, more than half use the Internet to view and share photos, and nearly as many send and receive email and search the Internet for information.

Centenarians were also almost as likely as baby boomers to have used an online dating service -- 6 percent of boomers, compared with 4 percent of the oldest generation.

"They are all realizing that the keys to longevity are around mental, physical and emotion health," said Randall.

About 10 percent of the 100-year-olds have watched a video on YouTube or listened to music on an iPod, according to the poll, but only 3 percent have used Facebook, and just one of them has used Twitter.

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How To Reach 100: Lifestyle Choices Vie With Genetics In Longevity

Shippen honored as Faculty Fellow by Texas AgriLife Research

Writer: Kathleen Phillips, 979-845-2872, ka-phillips@tamu.edu Contact: Dr. Dorothy Shippen, 979-862-2342, dshippen@tamu.edu

COLLEGE STATION Dr. Dorothy Shippen, professor of biochemistry and biophysics, has received the Texas AgriLife Research Senior Faculty Fellow Award.

The faculty fellows program, created in 1998, recognizes people who have contributed to the scholarly creation and dissemination of new knowledge through exceptional research leadership and grantsmanship.

Professors and associate professors in the College of Agriculture and Life Sciences at Texas A&M University who hold a joint appointment with AgriLife Research are eligible for the senior faculty fellow honor and $5,000 award.

Shippen was honored with Dr. Del Gatlin, fisheries researcher, and Dr. Bruce McCarl, agricultural economist, both of whom also received Senior Faculty Fellow awards, and with Dr. Binayak Mohanty, who was named Faculty Fellow.

I am extremely proud of these scientists whose studies have brought great advances in their fields and to the benefit of the public and our agency, said Dr. Craig Nessler, AgriLife Research director. Their scientific endeavors are yielding results that positively impact people in our state, nation and world.

Shippens studies on telomerase an enzyme which has special significance to aging and cancer research, led to 16 scientific papers being published in the last five years, according to her nomination. Among the journals that have published her research are Nature, Science and the Proceedings of the National Academy of Science.

Dr. Shippen rapidly carved a unique scientific niche for herself, as she is now unquestionably the worlds expert in this subfield of telomerase research, said Dr. Greg Reinhart, Texas A&M department of biochemistry and biophysics chair. The excitement derives not just from the important implication of her work for plant science, but also because this model organism, despite being a plant, is in many ways a better model of mammalian telomerase behavior than the more commonly studied organisms.

The citation noted that Shippen is frequently invited to speak at major scientific conferences and is known for her rigorous but popular teaching ability in college courses such as molecular biology and for her involvement in numerous scientific associations.

Shippen earned her bachelors in biology in 1982 from Auburn University and her doctorate in biology in 1987 from the University of Alabama.

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Shippen honored as Faculty Fellow by Texas AgriLife Research

The American Society for Microbiology honors Susan Sharp

Public release date: 6-Jun-2012 [ | E-mail | Share ]

Contact: Garth Hogan ghogan@asmusa.org American Society for Microbiology

Washington, DCJune 6, 2012 Anthony R. Richardson, Ph.D., Assistant Professor, Department of Microbiology & Immunology, University of North Carolina Hill School of Medicine, has been honored with one of two 2012 Merck Irving S. Sigal Memorial Awards. These awards, given annually to two young scientists to recognize and award excellence in basic research in medical microbiology and infectious diseases, are presented in memory of Irving S. Sigal, an instrumental figure in the early discovery of therapies to treat HIV/AIDS. "Richardson is a remarkably imaginative scientist whose work bridges microbial physiology, metabolism, and pathogenesis," states his nominator, William Goldman from the University of North Carolina. "His approach is interdisciplinary and mechanistic, and his work has profound implications for understanding the evolution and emergence of highly virulent pathogens."

Richardson received his B.S. in genetic and bioengineering from Purdue University, and his Ph.D. in microbiology and molecular genetics from Emory University. He completed his postdoctoral fellowship in bacterial physiology and pathogenesis at the University of Washington, where he worked in the laboratory of Ferric Fang, who described Richardson as "extremely curious, interactive, and remarkably well readan exceedingly bright and creative scientist who is poised to make major contributions to the field of bacterial pathogenesis."

Richardson's research has always been focused on the role of basic bacterial physiology in the virulence of important human pathogens. As a graduate student, he investigated the role of DNA repair in modulating immune avoidance in epidemic meningococcal meningitis. His findings showed that the rapid host-to-host spread of Neisseria meningitidis in sub-Saharan Africa during seasonal epidemics selected for strains lacking certain aspects of DNA repair. Given the nature of N. menigitidis, this resulted in bacterial populations with extremely diversified surface immunogenicity facilitating rapid adaptation to new hosts.

As a postdoctoral fellow, Dr. Richardson continued studying bacterial metabolism in the context of its interaction with host innate immunity. He showed that host-production of nitric oxide (NO), a broad-spectrum immune effector, targeted multiple metabolic enzymes inhibiting the growth of pathogenic bacteria. In contrast, he found that the human pathogen Staphylococcus aureus, unlike all other tested bacteria including coagulase negative staphylococci, was able to resist the cytotoxic effects of host NO and thrive in its presence. S. aureus NO-resistance was shown to be essential for full virulence and hinged on the ability of the bacterium to evoke a metabolic state inherently resistant to the effects of this immune radical.

In 2008, Dr. Richardson established his laboratory at the University of North Carolina at Chapel Hill, focusing on the metabolic adaptations of S. aureus to host immunitywork that was soon featured as a Science cover article. Richardson's research studies how the availability of host arginine affects the outcomes of S. aureus infections. While the host converts free arginine to NO in response to inflammatory stimuli, arginine can also be converted to a class of compounds known as polyamines under similar conditions. S. aureus can resist the effects of NO, but for unknown reasons certain species of polyamines are lethal to the pathogen. Dr. Richardson's laboratory studies the battle between the host and S. aureus over the fate of free arginine. Mark Smeltzer, University of Arkansas for Medical Sciences, calls his work "both insightful and scientifically compelling, without exception."

Richardson's late graduate mentor, Igor Stojilijkovic, summarized Richardson to Fang: "He has a big brain, but his heart is even bigger. He is one of those rare individuals who you know will make it in any endeavor he chooses to follow."

###

To view Dr. Richardson's biosketch, please visit: http://www.asm.org/index.php/awards-grants/current-merck-irving-s-sigal-memorial-award-laureate-b.html

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The American Society for Microbiology honors Susan Sharp

Innovation in Canada's Oil Sands Key to Advancing Economic Longevity and Sustainability of Global Energy Development

CALGARY, Alberta, June 7, 2012 (GLOBE NEWSWIRE) -- Invest in water management, productivity enhancement and technology optimization in the oil sands to build Canada's industrial future, says a new report from Deloitte. Putting innovation at the center of oil sands development, the report argues, will help to make Canada a leader in efficient and sustainable energy technology and produce benefits that extend far beyond not only the energy sector but also Canadian borders. The innovation imperative: A roadmap for oil sands advancement outlines how concentrated focus on innovation in these three primary areas will be crucial for an industry already laying the groundwork of a global model for responsible resource development.

"Innovation is central to leveraging our comparative advantage as a significant and democratically stable producer of energy," says Geoff Hill, a partner in Deloitte's Calgary office and national sector leader of its Oil & Gas practice. "Canada already leads the world in heavy oil technology, but achieving true progress requires sound practices and a strategic approach. This is about embedding research and development in the business culture and embracing activities and processes that lead to game-changing technologies critical for sustainable and enduring oil sands development."

Ongoing collaboration within industry, between industry and universities in the area of water innovation and management is crucial to maintaining a high-quality water supply, according to the report. The oil sands industry needs to put aside its traditionally autonomous and competitive approaches to R&D when it comes to water management, as these are increasingly out of step with the principle of sustainability. Instead, the emphasis should be on supporting research and public awareness efforts that focus on the overall importance of water as a world resource and then leading by example.

The report also notes that the sheer scale of oil sands development and the broad range of skills and technological expertise required provide a significant opportunity to help close Canada's productivity gap. Whether it's working with government to retool the immigration system, streamlining and speeding up the regulatory approval process or building consensus around the importance of R&D as a core innovation driver, the ultimate goal is to shift from trying to predict the future to creating it outright.

"Oil sands development is among the most important industrial activity in Canada to business, government and the general public," says Hill. "The innovation imperative contributes to the on-going debate around the sustainable development of this important resource, which we believe can lead to spinoff benefits, both nationally and globally, in terms of promoting Canadian-generated expertise in resource management in any number of applications."

The report also identifies five key areas in technology where targeted investment can help make continuous improvement the norm while establishing global centres of excellence. These include energy efficiency, waterless or near-waterless processes, tailings remediation, co-generation and clean technologies, and collaborative water management.

For a more detailed discussion of Deloitte's analysis and recommendations, read the full report at http://www.deloitte.com/ca/innovation-imperative.

Contact:

Sean McCann / Suzanne Settino

Hill+Knowlton Strategies Canada

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New, risk-free tests reveal full DNA of fetus by 18 weeks

LOS ANGELES -- Scientists have pieced together the entire DNA sequence of an 18-week-old fetus without having to use any invasive tests that could result in a miscarriage -- an advance that offers a glimpse of the future of prenatal testing.

Using blood drawn from the mother and a sample of saliva from the father, the researchers were able to scan the fetus' genome and determine whether it contained any of the myriad single-letter changes in the DNA code that can cause a genetic disorder.

They could even pinpoint which mutations were inherited from Mom, which came from Dad, and which were brand new.

If the technique is refined and the technology becomes inexpensive -- as many experts anticipate -- this type of prenatal testing could provide prospective parents with a simple, risk-free way to screen for a broad array of simple genetic disorders, according to the authors of a report in the Thursday, June 7, edition of Science Translational Medicine.

The work is based on the fact that small fragments of fetal DNA circulate in the blood of pregnant women.

Several biotech companies are developing tests that capture those DNA fragments and screen them for signs of Down syndrome and other disorders that result from having an extra copy of an entire chromosome.

But that type of screening is far easier than searching for single-letter variations in individual genes, said senior author Jay Shendure, a geneticist at the University of Washington in Seattle.

An

To set about their task, Shendure's team started by sequencing the genome of an anonymous pregnant woman, using a complete sample of her DNA obtained from her blood cells.

They also sequenced free-floating DNA fragments extracted from her blood plasma, repeating their work until they had decoded every part of the human genome 80 times.

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New, risk-free tests reveal full DNA of fetus by 18 weeks

Posted in DNA

DNA struggle stalls skeleton mystery

MYSTERY: Police are working to identify remains uncovered at a Port Waikato beach.

Attempts to indentify a mystery skeleton found at Port Waikato have been stalled by failed DNA tests.

Scientists are trying to extract a DNA profile from the remains found on Sunset Beach last month to determine who on their list of 30 possible matches - women aged 15 to 25, who disappeared more than 10 years ago - it could be.

Samples have been taken from the bones and teeth of the skeleton but the officer in charge of the investigation said two had so far failed. Different methods of extraction are now being tried.

Detective Inspector Mark Gutry said they were no closer to identifying the woman.

"If the first [test] had worked we would've had it, or the second one, so we've just got to wait, really."

Scientists were struggling because the skeleton had been buried so long, but Gutry is confident they will get a DNA profile they can compare to those on file.

"Once we get that we'll match it with the ones we have and then if it's not there we'll have to do some more work around that but we're pretty confident that we've got what we need."

Some of the missing person DNA was directly from those people, while some was from family members.

"It's something we do as part of our missing persons process - to look at dental records and DNA records and collate them on the file so that if anything comes up we can match them."

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Posted in DNA

Entire DNA of fetus revealed through risk-free testing

Scientists have pieced together the entire DNA sequence of an 18-week-old fetus without having to use any invasive tests that could result in a miscarriage an advance that offers a glimpse of the future of prenatal testing.

Using blood drawn from the mother and a sample of saliva from the father, the researchers were able to scan the fetus' genome and determine whether it contained any of the myriad single-letter changes in the DNA code that can cause a genetic disorder. They could even pinpoint which mutations were inherited from Mom, which came from Dad, and which were brand-new.

If the technique is refined and the technology becomes inexpensive as many experts anticipate this type of prenatal testing could provide prospective parents with a simple, risk-free way to screen for a broad array of simple genetic disorders, according to the authors of a report in Thursday's edition of Science Translational Medicine.

The work is based on the fact that small fragments of fetal DNA circulate in the blood of pregnant women.

Several biotech companies are developing tests that capture those DNA fragments and screen them for signs of Down syndrome and other disorders that result from having an extra copy of an entire chromosome.

But that type of screening is far easier than searching for single-letter variations in individual genes, said senior author Jay Shendure, a geneticist at the University of Washington in Seattle.

An additional chromosome is "the equivalent of an extra chapter in a book," he said. "What we're trying to do is pick up a typo in a word."

To set about their task, Shendure's team started by sequencing the genome of an anonymous pregnant woman, using a complete sample of her DNA obtained from her blood cells. They also sequenced free-floating DNA fragments extracted from her blood plasma, repeating their work until they had decoded every part of the human genome 80 times.

That plasma contained a mix of 10% fetal DNA and 90% maternal DNA, all in tiny fragments. The scientists needed to be able to tell which pieces were from the mother and which belonged to the fetus.

To solve that problem, the scientists relied on the fact that genetic material is inherited in long strands of DNA, called chromosomes and that tiny genetic variations on the same chromosome are usually inherited together, in blocks known as haplotypes. If a given haplotype was present in the fetus as well as in the mother, it would be detected in the plasma in extra amounts.

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Massey scores big in biology

Biology students from Vincent Massey High School tangled with students from around the world in the annual University of Toronto National Biology Competition and they did their school proud.

This competition is open to schools worldwide, with the majority of participating schools coming from Canada, the United States and parts of Asia.

Out of the 300 schools participating, the Massey team placed 16th.

More impressively, Massey was the top scoring team out of the 17 Manitoba schools, public and private, that entered the competition.

To be eligible for the team competition, a school must have at least five participants. The team score is calculated based on the top five student scores.

Masseys team included Isaac Kim, Cody Cherepuschak, Gol Roberts, Eric Badiou and Leslie Skead, some of whom racked up some impressive individual honours as well.

Roberts, a Grade 12 student, was awarded a National Biology Scholar Award as her score ranked her 85th highest score out of the 4,332 students who competed.

Kim, a Grade 11 student, was awarded a National Biology Scholar with Distinction Award for having the 49th highest score out of the 4,332 students who competed placing him in the top two per cent of all the students who wrote the exam. He was also awarded the Certificate of Achievement for having received the top mark out of the students who wrote the exam from Vincent Massey High School.

Cherepuschak, another Grade 11 student, also won a National Biology Scholar Award for having the 52nd highest score out of the 4,332 students. He, too, placed in the top two per cent of students who wrote the exam.

Biology teacher Lindsay Metruk is proud of her students for accomplishing such impressive scores in this prestigious contest and credits the rigour of the Advanced Placement program at Massey for such a strong foundation in biology.

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The American Society for Microbiology honors Anthony R. Richardson

Public release date: 6-Jun-2012 [ | E-mail | Share ]

Contact: Garth Hogan ghogan@asmusa.org American Society for Microbiology

Washington, DCJune 6, 2012 Anthony R. Richardson, Ph.D., Assistant Professor, Department of Microbiology & Immunology, University of North Carolina Hill School of Medicine, has been honored with one of two 2012 Merck Irving S. Sigal Memorial Awards. These awards, given annually to two young scientists to recognize and award excellence in basic research in medical microbiology and infectious diseases, are presented in memory of Irving S. Sigal, an instrumental figure in the early discovery of therapies to treat HIV/AIDS. "Richardson is a remarkably imaginative scientist whose work bridges microbial physiology, metabolism, and pathogenesis," states his nominator, William Goldman from the University of North Carolina. "His approach is interdisciplinary and mechanistic, and his work has profound implications for understanding the evolution and emergence of highly virulent pathogens."

Richardson received his B.S. in genetic and bioengineering from Purdue University, and his Ph.D. in microbiology and molecular genetics from Emory University. He completed his postdoctoral fellowship in bacterial physiology and pathogenesis at the University of Washington, where he worked in the laboratory of Ferric Fang, who described Richardson as "extremely curious, interactive, and remarkably well readan exceedingly bright and creative scientist who is poised to make major contributions to the field of bacterial pathogenesis."

Richardson's research has always been focused on the role of basic bacterial physiology in the virulence of important human pathogens. As a graduate student, he investigated the role of DNA repair in modulating immune avoidance in epidemic meningococcal meningitis. His findings showed that the rapid host-to-host spread of Neisseria meningitidis in sub-Saharan Africa during seasonal epidemics selected for strains lacking certain aspects of DNA repair. Given the nature of N. menigitidis, this resulted in bacterial populations with extremely diversified surface immunogenicity facilitating rapid adaptation to new hosts.

As a postdoctoral fellow, Dr. Richardson continued studying bacterial metabolism in the context of its interaction with host innate immunity. He showed that host-production of nitric oxide (NO), a broad-spectrum immune effector, targeted multiple metabolic enzymes inhibiting the growth of pathogenic bacteria. In contrast, he found that the human pathogen Staphylococcus aureus, unlike all other tested bacteria including coagulase negative staphylococci, was able to resist the cytotoxic effects of host NO and thrive in its presence. S. aureus NO-resistance was shown to be essential for full virulence and hinged on the ability of the bacterium to evoke a metabolic state inherently resistant to the effects of this immune radical.

In 2008, Dr. Richardson established his laboratory at the University of North Carolina at Chapel Hill, focusing on the metabolic adaptations of S. aureus to host immunitywork that was soon featured as a Science cover article. Richardson's research studies how the availability of host arginine affects the outcomes of S. aureus infections. While the host converts free arginine to NO in response to inflammatory stimuli, arginine can also be converted to a class of compounds known as polyamines under similar conditions. S. aureus can resist the effects of NO, but for unknown reasons certain species of polyamines are lethal to the pathogen. Dr. Richardson's laboratory studies the battle between the host and S. aureus over the fate of free arginine. Mark Smeltzer, University of Arkansas for Medical Sciences, calls his work "both insightful and scientifically compelling, without exception."

Richardson's late graduate mentor, Igor Stojilijkovic, summarized Richardson to Fang: "He has a big brain, but his heart is even bigger. He is one of those rare individuals who you know will make it in any endeavor he chooses to follow."

###

To view Dr. Richardson's biosketch, please visit: http://www.asm.org/index.php/awards-grants/current-merck-irving-s-sigal-memorial-award-laureate-b.html

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The American Society for Microbiology honors Anthony R. Richardson

Eleven Named to GSC’s All-Academic Team

Birmingham, AL -- The Valdosta State spring sports represented VSU at its best with a Gulf South Conference high 11 student-athletes named to the GSCs All-Academic Team. Thirty-four VSU student-athletes earned a high enough grade point average to be listed on the GSC Academic Honor Roll.

Valdosta State softball led the way with five players earning All-Academic Team honors. Marti Littlefield earned her third consecutive Academic All-GSC award while Natalia Morozova was a unanimous selection this season. Littlefield earned a 3.29 in exercise physiology while Morozova earned a 3.63 GPA in international business.

Another VSU senior infielder to make the list was April Hutchens. She finished with a 3.36 in deaf education. Outside of the softball seniors, two underclassmen made the list with junior outfielder Morgan Johnson earning a 3.66 in nursing while sophomore pitcher and Elite 89 Award winner Brianna Hancock notched a 3.95 in business administration.

Womens tennis placed three on the squad with Juliana Boehm, Michelle Fischer and Alina Nagel. All three were All-GSC selections this season but still managed strong GPAs. Boehm earned a 3.34 in exercise physiology. Fischer notched a 3.82 in psychology and Nagel earned a 3.76 in business administration.

Each of the mens sports placed one student-athlete on the squad. Mens tennis player Konstantin Kutschenko was a unanimous selection with a 3.71 GPA in psychology for his second honor on the All-Academic GSC squad. Representing baseball was Chaz Bagwell, another unanimous selection making his second team. He earned a 3.53 in marketing. Rounding out the VSU representatives on the All-Academic GSC squad was Austin Graham. The sophomore earned a 3.37 in finance.

In addition to leading the conference in All-Academic GSC selections, Valdosta State also led the GSC in softball and womens tennis Academic Honor Roll honorees.

Below are all VSU student-athletes to be named to the GSC Academic Honor Roll:

Baseball Junior Chaz Bagwell 3.53 in Marketing Junior Zack John 3.50 in Graphic Design Sophomore Brent Nelson 3.65 in Marketing Junior Ben Watson 3.50 in Business Management

Softball Freshman Courtney Albritton 4.00 in Middle Grades Education Sophomore April Collins 3.04 in Physical Education Senior Julia Fink 3.82 in Biology Sophomore Brianna Hancock 3.95 in Business Administration Senior April Hutchens 3.36 in Deaf Education Freshman Fran Johnson 4.00 in Chemistry Junior Morgan Johnson 3.66 in Nursing Senior Marti Littlefield 3.29 in Exercise Physiology Senior Natalia Morozova 3.63 in International Business Freshman Angela OConnor 3.58 in Interior Design Junior Ashley Steinhilber 3.55 in Biology Sophomore Erika Trojan 3.46 in Psychology Junior Sarah Vaughn 3.07 in Exercise Physiology Senior Clare Wamsley 3.20 in Early Childhood Special Ed

Mens Tennis Freshman Tammo Haake 3.25 in International Business Senior Christian Hansen 3.04 in Business Management Freshman Sebastian Jasyk 3.29 in International Business Junior Konstantin Kutschenko 3.71 in Psychology

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Eleven Named to GSC’s All-Academic Team

Sir Andrew Huxley dies at 94; Nobel-winning physiologist

Sir Andrew Huxley, the British researcher who shared the 1963 Nobel Prize in Physiology or Medicine for his discoveries of how nerve impulses are transmitted through cells, died May 30. He was 94.

His death was announced by the University of Cambridge's Trinity College, where he served as master from 1984 to 1990, but no details were released.

Biologists had known since the 1771 experiments of Italian physicist Luigi Galvani that giving a frog leg an electrical shock would cause it to contract, suggesting that muscle activity was electrically regulated. But it was not clear how the tissues could generate such an electrical stimulus and how it could be transmitted through cells.

Huxley and Hodgkin approached the problem by studying a squid nerve cell known as the giant axon. The giant axon, which can be up to 1 millimeter (0.04 inches) in diameter, stretches the length of the squid's body to control ejection of water for propulsion, and nerve impulses travel especially rapidly through it.

By placing tiny electrodes in the axon at various locations, they were able to measure the electrical potential inside the nerve as it transmitted an electrical current. They concluded that the current was carried by electrically charged atoms called ions. When the current reaches each cell, it causes a channel known as a sodium gate to open, allowing sodium ions to flow into the cell.

Once enough sodium is in the cell, that triggers a second set of gates on the opposite end that allow potassium ions to escape. Those ions cause the process to repeat at the next cell.

The gates themselves could not be visualized with the technology available at the time, but Huxley, working on a very primitive computer, used the laws of physics to calculate the electrical potentials that should be obtained if their model was correct. The calculated values were very close to those that were observed, confirming their hypothesis. Only much later were the ion channels actually imaged.

Huxley and Hodgkin shared their Nobel with Sir John Eccles of Australia, who explained how signals were transmitted between cells. Both Britons were knighted for their work in 1974.

Huxley later worked to explain how muscle fibers contract. For that work, he devised and built a microtome to make very thin slices of tissue for study in the electron microscope and a micromanipulator.

Andrew Fielding Huxley was born Nov. 22, 1917, in London to a celebrated family. His grandfather was biologist Thomas Henry Huxley, an early supporter of Charles Darwin's theory of evolution. His father, Leonard, was a writer who, among other things, compiled a history of Thomas Huxley. Andrew's older half-brothers were the author Aldous Huxley and biologist Julian Sorel Huxley.

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Sir Andrew Huxley dies at 94; Nobel-winning physiologist

NinePoint Medical Receives European CE Mark Approval and ISO Certification for NvisionVLE Imaging System

CAMBRIDGE, Mass.--(BUSINESS WIRE)--

NinePoint Medical, Inc., an emerging leader in the development of medical devices for in vivo pathology, today announced that it has received European CE mark approval for the NvisionVLEImaging System. The CE Mark is for the companys optical endomicroscopy imaging devices for diagnosis of mucosa and submucosa diseases. The company has also received ISO 13485:2003 certification, an international standard governing the requirements of a quality management system for medical devices and related services, for the companys Cambridge facility. The CE marking or Conformite Europeene certifies that a product has met European Union (EU) requirements for marketing in Europe.

The ISO certification and CE mark approval are important milestones for NinePoint Medical and, along with our recently announced 510(k) clearance from the FDA, strongly position the NvisionVLE Imaging System for a commercial launch in 2013, said Charles Carignan, M.D., president and chief executive officer of NinePoint Medical.

NinePoint Medical recently initiated a clinical trial to evaluate high-resolution optical imaging of Barretts esophagus using the NvisionVLE Imaging System. Barretts esophagus is one of the most common precursors to esophageal adenocarcinoma, the fastest growing cancer in the Western world. With the CE Mark, the company will now add two sites in Europe to the clinical trial. In addition, in January 2012 the company announced 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market its NvisionVLE Imaging System for use as an imaging tool in the evaluation of human tissue microstructure by providing two-dimensional, cross sectional, real-time depth visualization. The NvisionVLE Imaging System is the first volumetric, optical coherence tomography (OCT) device cleared by the FDA for endoscopic imaging that generates cross sectional and longitudinal images simultaneously, in real time.

About NinePoint Medical, Inc.

NinePoint Medical, Inc. is a transformational medical device company developing innovative, real-time, in vivo pathology devices focused on dramatically improving patient care. Through its proprietary NvisionVLE Imaging System, NinePoint intends to bridge the gap between the diagnosis and treatment of disease. The NvisionVLE Imaging System will enable physicians and pathologists, for the first time, to view real-time, high-resolution, volumetric images of organs and tissues up to 3mm deep at better than 10 micron resolution. Initially, NinePoint is focusing on devices that enable real-time, endoscopic screening and surveillance of diseases of the mucosa of various tissues that are often precancerous. Eventually, the company intends to develop medical devices that provide physicians with immediately actionable information, which will allow them to diagnose and treat patients during the same procedure. This convergence of access, diagnosis and treatment during one procedure is expected to improve patient experiences and outcomes, improve the efficiency of care and provide important savings to the health care system. Headquartered in Cambridge, Mass., NinePoint is backed by Third Rock Ventures and Prospect Venture Partners. For more information, please visit http://www.ninepointmedical.com.

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NinePoint Medical Receives European CE Mark Approval and ISO Certification for NvisionVLE Imaging System

Nutrition Push May Be a Little Better for Kids, Great for Disney

Disney is pushing healthier food options. But will kids bite?

"With this new initiative, Disney is doing what no major media company has ever done before in the U.S.--and what I hope every company will do going forward."

That is Michelle Obama's view on Disney's new guidelines to curb junk food advertising. It's publicity that money can't buythe First Lady simultaneously heralding your company as a leader in its field and inviting other companies to follow suit. The decision clearly comes with political heft behind it, but how meaningful of a change the company is making remains in question.

[Read about the CBO's latest dismal debt projections.]

Under the new guidelines, all food and beverages advertised, sponsored, or promoted on outlets including the Disney Channel, Radio Disney, and Disney websites will have to conform to limits on areas like caloric, sodium, and sugar content.

"We've been looking at the Disney criteria they're using, and they're a little bit better than the criteria that the food industry already uses, but they're not great. So by no means will this limit children's exposure to junk food," says Jennifer Harris, director of marketing initiatives at Yale University's Rudd Center for Food Policy and Obesity.

She points to the Children's Food and Beverage Advertising Initiative, a program in which some of the nation's largest food companies have come together to self-regulate the products advertised to children. Harris notes that the Disney guidelines differ little from the CFBAI guidelines already in place.

For example, Disney's new guidelines allow meals marketed to children to have no more than 600 caloriesthe same limit established by the CFBAI. Disney and CFBAI also both allow a six-ounce yogurt to have a maximum of 170 calories. Likewise, both allow 350 calories for a main dish or entree.

To be fair, cutting calories is still cutting calories; the company allows slightly lower counts of calories for several other foods, like cereals (130 per ounce versus CFBAI's 150 per serving for most children's cereals) and juice (140 for eight ounces versus CFBAI's 160 per serving), as well as "mini-meals" (400 versus CFBAI's 450 for "small meals").

[Read about the latest jobs numbers.]

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Nutrition Push May Be a Little Better for Kids, Great for Disney

Guiding Stars® To Present School Nutrition Webinar on June 19

PORTLAND, Maine, June 6, 2012 /PRNewswire/ --Guiding Stars, the first store-wide nutrition guidance program for rating food, today announced plans to present a free, open-to-all webinar on the impact of school nutrition programs and strategies for improving the diets of school-age children, scheduled for June 19th at 2:00pm EDT.

The webinar will feature Guiding Stars Expert Chef Erin Dow, and Guiding Stars Consulting Dietician, Allison Stowell MS, RD, CDN. During the webinar, Dow and Stowell will offer insights on:

The live, one-hour webinar will target Registered Dietitians and Dietetic Technicians, as well as those who have an interest in understanding how school nutrition programs and our approach to feeding our children will impact their future health. The webinar is registered and approved for one CPE unit and meets learning codes 4100, 5070, 8000 and 8100.

"In the Guiding Stars webinar, we will highlight some of the most pressing changes that need to be made to provide U.S. children with more nutritious food and school nutrition programs," said Erin Dow.

"Throughout the U.S.in Daycares, Schools, Kid's Camp and Children's Hospital Food Servicethe impact of poor nutrition is detrimental to a child's health. Our webinar is designed to provide cost effective strategies you can use to provide children with nutritious food in the future," said Allison Stowell.

For more information on the Guiding Stars webinar, or to reserve your spot, visit http://guidingstars.com/webinar/

About Guiding Stars Licensing Co.Since 2006, Guiding Stars has been leading the way in helping consumers make nutritious food choices and recently received a U.S. Patent for the Guiding Stars nutrition rating algorithm. The Guiding Stars nutrition guidance program is a simple, easy-to-understand tool for making good nutrition choices and is designed to make a positive and lasting impact on public health. Guiding Stars is currently found in more than 1,700 supermarkets including Food Lion, Hannaford, Sweetbay, Homeland, Kings Super Market and Marsh Supermarkets. Guiding Stars has also expanded into public schools, colleges and hospitals and appears on the Shopper mobile iPhone application. Additional information can be found atwww.guidingstars.com

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Guiding Stars® To Present School Nutrition Webinar on June 19

F3 Nutrition Announces Sponsorship Of "The Kettlebell Queen" Lauren Brooks

DEERFIELD BEACH, Fla., June 6, 2012 /PRNewswire/ --Mark Post, President, F3 Nutrition, LLC today proudly announced that F3 Nutrition will sponsor "The Kettlebell Queen" and fitness author Lauren Brooks and that she will contribute greatly to the company's goal to meet the Fit, Form and Function needs of athletes and fitness seekers today.

"When we were looking for athletes and fitness and nutrition professionals to sponsor, Lauren Brooks really caught my attention due to her expertise, passion for fitness, and many accomplishments in the industry," said Post. "Lauren will not only serve as a living example of fitness, she will also publish nutrition columns and write other health and wellness articles on behalf of the company. I'm excited to have her on board at Team F3 and look forward to working with her."

"I'm honored and excited to be a part of the F3 Nutrition Team as one of their sponsored athletes," said Brooks. "I am very particular with what I recommend to my clientele, especially as an athlete, but F3 Nutrition has accomplished experts who have developed high quality supplements that I can use for my training and recommend with confidence to friends and clients."

Brooks is the owner of On the Edge Fitness and the creator of the highly acclaimed three-volume DVD series "The Ultimate Body Sculpt and Conditioning with Kettlebells." She is an author of the book "Kettlebells for Women" and is the creator of the only pregnancy kettlebell DVD that exists today "Baby Bells." Brooks also has an iPhone/iPad application under development that will be available later this year.

Brooks earned her B.S. in Kinesiology with an emphasis in Fitness, Nutrition, and Health from San Diego State University in 2002. She became kettlebell certified in 2005 and currently holds certifications as a Russian Kettlebell Instructor Level 1 and 2, RKC Team Leader, ACE Fitness Trainer, Clinical Nutritionist, Functional Movement Specialist, TRX and Battling Ropes. Lauren makes sure to emphasize Nutrition, Lifestyle, Exercise, and a positive mental attitude. Part of Lauren's lifestyle is being a mother to her two daughters.

Brooks has conducted kettlebell live workshops worldwide. Drawing on her own experience and research, she inspires others to stay fit even after going through pregnancies and surgeries. She is the writer of many fitness and nutrition articles that appear in online magazines, fitness websites, and hard copy magazines. Brooks has had the privilege of helping and inspiring thousands of people from all walks of life achieve their fitness dreams.

Brooks added, "I look forward to working with the outstanding group of people at F3 and with the other professional athletes. I already have trust in the F3 brand because I am highly impressed with the research that has gone in to formulating their sports performance and health supplements. It will be easy to refer people to F3."

For more information about Lauren Brooks, please visit her Team F3 Athlete page at http://www.f3nutrition.com, visit her website OnTheEdgeFitness.com, or http://www.facebook.com/laurenbrooks.ontheedgefitness and through her blog at kbellqueen.blogspot.com.

About F3 Nutrition: F3 Nutrition focuses on the three critical elements in building a successful high-performance sports nutrition product: Fit for the specific purpose; deliver through the best Form available; Function for the specific goal of the individual. The F3 Nutrition portfolio will consist of pre-training and post-training products and also protein and health wellness category products. Each of the company's products will contain unique to market formulations to assist in endurance, strength and recovery. In 2012, F3 Nutrition is scheduled to attend and exhibit at the CrossFit Games Worldwide Expo, IDEA World Fitness Convention, Europa Sports & Supplement Expo and the UFC Fan Expo to showcase its products and provide samples to awaiting fitness enthusiasts. F3 Nutrition, LLC products will be distributed online at http://www.f3nutrition.com and on shelves at retail outlets including fitness centers and gyms, health stores, sports retailers and online nutrition supplement retailers. For more information, email info@f3nutrition.com. Please visit us online at F3Nutrition.com or on Facebook at http://www.facebook.com/f3nutrition.

Press Contact: Jen Wenk press@f3nutrition.com 702.635.0995 @jenwenk

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F3 Nutrition Announces Sponsorship Of "The Kettlebell Queen" Lauren Brooks

The American Society for Microbiology honors Geoffrey L. Smith

Public release date: 6-Jun-2012 [ | E-mail | Share ]

Contact: Garth Hogan ghogan@asmusa.org American Society for Microbiology

Washington, DCJune 6, 2012 Geoffrey L. Smith, Ph.D., Wellcome Trust Principal Research Fellow and Head, Department of Pathology, University of Cambridge, and Fellow of Emmanuel College, Cambridge, has been bestowed the 2012 GlaxoSmithKline International Member of the Year Award, recognizing exemplary leadership in the international microbiological community. His nominator, Molly Hughes of the University of Virginia, says Smith is "internationally recognized as an outstanding scientist due to his numerous original contributions to the field of virology and the role he plays as a leader in a number of scientific institutions."

Smith received his B.Sc. in Microbiology and Biochemistry from the University of Leeds, and his Ph.D. from the National Institute for Medical Research, Mill Hill, London, while working with influenza virus in the laboratory of Alan Hay. He then held a Wellcome Trust Fellowship at the National Institute for Medical Research, before becoming a postdoctoral fellow at the National Institutes of Health in the laboratory of Bernard Moss. There, together with Michael Mackett, he developed vaccinia virus as an expression vector and established the use of genetically engineered viruses as live vaccines, a principle applied subsequently to other viruses and microorganisms.

After returning to the United Kingdom, Smith continued working with poxviruses at the University of Cambridge, the University of Oxford, and the Imperial College London. He is now Head of the Department of Pathology at the University of Cambridge, where he studies the interactions of poxviruses (particularly vaccinia virus) with the host cell and immune system. His research group has contributed to the current understanding of how these poxviruses replicate and spread and how they interfere with innate immunity, findings that provide an "important contribution to not only the field of poxviruses, but have also had widespread implications, particularly in the field of immunology," says Hughes.

"Smith has played an important role in promoting microbiology and advising on science policy both nationally and internationally," says Michael Oldstone of Scripps Research Institute. His sweeping service record demonstrates his commitment to the international community. Smith is currently President of the International Union of Microbiological Societies, Chairman of the WHO Advisory Committee for Variola Virus (smallpox) Research, Chairman of the Royal Society Committee for Scientific Aspects of International Security, a member of the Royal Society Science Policy Advisory Group and the UK Defence Scientific Advisory Council, and a Governor of the Lister Institute of Preventive Medicine. He is a Corresponding Member of the Gesellschaft fr Virologie, and a Fellow of the Academy of Medical Sciences, the Institute of Biology, the European Academy of Microbiology, the German National Academy of Sciences (Leopoldina), and the Royal Society. In 2003 he became Editor-in-Chief of the Journal of General Virology. He was awarded the Feldberg Foundation Prize in Medical and Biological Science to promote Anglo-German Friendship.

"Smith has been a tireless contributor to the science of microbiology in general and virology in particular throughout his career. His ability to maintain an enormous and global variety of research, teaching, and service activities and do each expertly is awe-inspiring," says Richard Condit, University of Florida.

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To view Dr. Smith's biosketch, please visit: http://www.asm.org/index.php/awards-grants/current-glaxosmithkline-international-member-of-the-year-award-laureate.html

The GlaxoSmithKline International Member of the Year Award will be presented during the 112th General Meeting of the ASM, June 16 - 19, 2012 in San Francisco, California. ASM is the world's oldest and largest life science organization and has more than 40,000 members worldwide. ASM's mission is to advance the microbiological sciences and promote the use of scientific knowledge for improved health and economic and environmental wellbeing.

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The American Society for Microbiology honors Geoffrey L. Smith

The American Society for Microbiology honors Jayaraman Gowrishankar

Public release date: 6-Jun-2012 [ | E-mail | Share ]

Contact: Garth Hogan ghogan@asmusa.org American Society for Microbiology

Washington, DCJune 6, 2012 The 2012 Moselio Schaechter Distinguished Service Award will be presented to Jayaraman Gowrishankar, Ph.D., Director, Centre for DNA Fingerprinting and Diagnostics (CDFD), and leader of the Laboratory of Bacterial Genetics, CDFD, Hyderabad, India. This award, named in honor of Professor Moselio Schaechter, former ASM President, honors an ASM member who has shown exemplary leadership and commitment towards the substantial furthering of the profession of microbiology in research, education or technology in the developing world. Gowrishankar is honored for "his dual responsibilities as the Director of the DNA diagnostics facility as well as the leader of a team of scientists, and also for his direct contributions to basic microbiology," states his nominator, Laszlo Csonka, Purdue University.

Gowrishankar received his undergraduate degree in medicine at the Christian Medical College in Vellore, South India. In 1979, he took a step back from a future career as a physician and followed a love of basic research. He pursued graduate studies in bacterial genetics under Jim Pittard at the University of Melbourne, Australia. He received his Ph.D in 1983, and returned to India to begin his independent research career as a Scientist and Group Leader at the Centre for Cellular and Molecular Biology in Hyderabad. In 2000, Gowrishankar moved to the CDFD, where he has been Director for the last six years and head of the Laboratory of Bacterial Genetics.

Research in Gowrishankar's laboratory has covered different aspects of the physiology and genetics of Escherichia coli, including osmoregulation, the occurrence of spontaneous mutations in non-dividing cells, arginine export, replication fork progression, and factor-dependent transcription termination. With about fifty papers published in the peer-reviewed journals (most with no more than two co-authors), his has been one of the most successful E. coli labs outside of the developed world. In addition, several of his students have gone on subsequently to establish their own independent research programs in microbiology. His group was also the first in India to patent and earn royalties from a genetically modified organism, in the form of an engineered E. coli strain for salt-induced overproduction of recombinant proteins.

Gowrishankar is also known for his many contributions outside of the laboratory. "While continuing his research at CDFD, he also plays a key role as Institute Director to set up the diagnostic systems for DNA tests of heritable genetic disorders, and moreover to provide young scientists with the chance to train in bacterial molecular genetics," explains Akira Ishihama, Hosei University, Tokyo, Japan. Csonka elaborates, "CDFD houses approximately twenty scientists conducting basic research in diverse areas ranging from bacterial physiology to bioinformatics and structural biology, whose research is overseen and guided by Gowrishankar."

Over the years, Gowrishankar has been engaged in science-related public activities in India and beyond, including participating in training programs on intellectual property protection and exploitation, contributing to the Indo-Japan Collaborative Program on Modern Biology, and publishing a variety of articles on matters of science policy. In a letter in ASM News in 1994, he spoke of the inequity inherent in the imposition of page charges for papers published by groups from the developing world, and appealed for their waiver. He is an elected Fellow of the major Science Academies in India as also of the International Molecular Biology Network for Asia and the Pacific Rim, and has received several major national awards and honors in recognition of his achievements in science.

Max Gottesman, Columbia University Medical Center, summarizes: "I have been struck by his quick intelligence and his encyclopedic knowledge of scientific literature. For me, he has been a source of many useful suggestions. He is open and interactiveI have the utmost admiration for Gowrishankar, and support him without hesitation."

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To view Dr. Gowrishankar's biosketch, please visit: http://www.asm.org/index.php/awards-grants/current-moselio-schaechter-distinguished-service-award-laureate.html

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The American Society for Microbiology honors Jayaraman Gowrishankar

The American Society for Microbiology honors Stephen J. Giovannoni

Public release date: 6-Jun-2012 [ | E-mail | Share ]

Contact: Garth Hogan ghogan@asmusa.org American Society for Microbiology

Washington, DCJune 6, 2012 Stephen J. Giovannoni, Ph.D., Professor, Department of Microbiology, Oregon State University, has been honored with the 2012 USFCC/J. Roger Porter Award. This award recognizes outstanding efforts by a scientist who has demonstrated the importance of microbial biodiversity through sustained curatorial or stewardship activities for a major resource used by the scientific community. It honors the memory of J. Roger Porter and his remarkable contributions to science. Giovannoni is honored for "more than a decade of leading the field of marine microbiology in successfully bridging the divide between culture-based and culture-independent studies, with a foot solidly in both camps," says nominator Norman Pace, University of Colorado.

Giovannoni received his B.A. in biology from the University of California, San Diego, where his first experience with bacteria was raising cells and isolating photosynthetic reaction center proteins for physicist George Feher. He then earned his M.A. in biology from Boston University, where he studied under Lynn Margulis, and continued on to the University of Oregon to receive his Ph.D. in biology. Here he worked with Richard Castenholz to isolate and describe novel thermophilic bacteria from Yellowstone National Park. After graduating, he joined Pace's research team (then at Indiana University) to develop molecular techniques for studying microbial ecology, where Pace says Giovannoni participated in "the earliest culture-independent forays into the natural microbial world of the oceans."

Giovannoni next accepted a faculty position at Oregon State University, where he remains today. His research focuses on microbial diversity, genomics, and ecology in oceanic ecosystems. "As he established his own lab, he was the first to use PCR with universal sequencing primers to conveniently access environmental rRNA genes," explains Pace. Giovannoni developed PCR methods to clone rRNA genes from microbial communities and identified many cosmopolitan, uncultivated bacterioplankton clades. Following up on this work, his research team focused on the Sargasso Sea. They described in rich detail the seasonal patterns and stratification of planktonic microbial communities, including a group of proteobacteria that became known as SAR11. "His work on the SAR11 cladethe most abundant group of bacteria in the global oceanhas served as a model for marine bacterial physiology, ecology, and evolution, including novel growth strategies such as genome reduction," describes David Karl, University of Hawaii. Kenneth Nealson further explains, "the cultivation and characterization of the Pelagibacter group [a member of the SAR11 clade], has had a huge impact on our understanding of marine microbiology. His approach was to use comparative genomic approaches to characterize these organisms, probing the nature of their ability to thrive in the nutrient-limited ocean. His papers on genome streamlining are classics in the fieldonly someone with Giovannoni's background and insight could accomplish this."

In 2000, Giovannoni founded the High Throughput Culturing Laboratory (HTCL) at Oregon State University with the aim of culturing globally important marine bacterioplankton. New technologies developed by the HTCL led to the successful cultivation of many oligotrophic strains of bacteria and more than 27 genome sequences. In 2011, his research team reported that SAR11 likely share a common ancestor with mitochondria. Their current research is focused on understanding SAR11 metabolism, and how these cells interact with marine dissolved organic carbon.

In addition to his teaching duties, Giovannoni serves as a Founding Editor for Annual Reviews of Marine Science and Associate Editor for The ISME Journal and Environmental Microbiology. His outstanding contributions have been honored with many awards, including the Gilfillan Award for Distinguished Scholarship in Science, the Milton Harris Award for Exceptional Achievement in Microbiology and Sugihara Young Faculty Research Award from Oregon State University, and the Emerging Scholar Award from Phi Kappa Phi. He is also a Fellow of the American Academy of Microbiology.

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To view Dr. Giovannoni's biosketch, please visit: http://www.asm.org/index.php/awards-grants/current-usfccj-roger-porter-award-laureate.html

The USFCC/J. Roger Porter Award will be presented during the 112th General Meeting of the ASM, June 16 - 19, 2012 in San Francisco, California. ASM is the world's oldest and largest life science organization and has more than 40,000 members worldwide. ASM's mission is to advance the microbiological sciences and promote the use of scientific knowledge for improved health and economic and environmental wellbeing.

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The American Society for Microbiology honors Stephen J. Giovannoni

The American Society for Microbiology honors Lilliam Casillas-Martinez

Public release date: 6-Jun-2012 [ | E-mail | Share ]

Contact: Garth Hogan ghogan@asmusa.org American Society for Microbiology

Washington, DCJune 6, 2012 Lilliam Casillas-Martnez, Ph.D., has been honored with the 2012 Carski Foundation Distinguished Undergraduate Teaching Award. Casilla is a Professor in the Biology Department at the University of Puerto Rico-Humacao (UPRH). One of Casillas' strongest passions is to educate and help women from low income homes, or "invisible students," as she calls them. Because there are so few Latin American women in positions of power, she feels that mentoring young women is crucial to their development. Nominator and former student Lorraine D. Rodriguez-Rivera, now a Ph.D. candidate in the Laboratory for Food Microbiology and Pathogenesis of Foodborne Diseases at Cornell University, describes Casillas' effect on others: "Casillas has had a profound impact on the professional development of many women in Puerto Rico. As my undergraduate advisor, she provided me with valuable tools for my career. I would like to become a professor and inspire minority students the way she inspired me towards becoming a professional in microbiology."

Casillas received her B.S. in Industrial Microbiology from the University of Puerto Rico, Mayaguez, and her Ph.D. in Microbiology from the University of Connecticut, Storrs. There she studied Bacillus subtilis under the tutelage of Peter and Barbara Setlow. Upon completion of her doctorate, Casillas attended the Microbial Diversity Course in Woods Hole and she continues to conduct research in emerging fields such as geomicrobiology and metagenomics. Once at the University of Puerto Rico-Humacao, Casillas started a productive collaboration in geomicrobiology with Pieter Visscher from the Integrative Geosciences Department at the University of Connecticut.

One of Casillas' proud accomplishments is the NSF-funded Cabo Rojo Salterns Microbial Observatory, where undergraduate students learn how to conduct in situ studies. To date, more than one hundred Puerto Rican students have received hands-on training in techniques in geomicrobiology and metagenomics. In addition to working on research projects, undergraduate students in Casillas' lab are required to design outreach activities to implement during visits to local public schools. Her laboratory is well known for its active participation in science fairs, open houses, and the development of workshops for local high school teachers.

Casillas' nomination was supported by Mayra Cancel, a high school teacher from the Puerto Rico public school system. "Casillas' efforts have changed my perception of the community of researchers in Puerto Rico and have strengthened their ties with teachers of the public system education," explained Cancel. "Education is basic for human progress, individually and collectively. Casillas' workshops for teachers strengthen the collective of research groups in the schools of our community and have served as motivation to reaffirm our confidence in higher education and its commitment to educational principles."

With the support of several agencies, Casillas has been able to combine undergraduate education with research projects such as characterizing novel microorganisms, constructing metagenomic libraries from various extreme environments in Puerto Rico, and screening for novel antibiotics. In the last decade, more than fifty undergraduates from her laboratory have continued graduate studies. "Casillas' success as a teacher and a mentor is evident in the triumphs of her students. Her down-to-earth style of mentoring, her charismatic personality and her availability to her students allowed us to approach her whenever advice was needed," described a former undergraduate student, Angel Casanovanow a Ph.D. candidate in the Microbiology Doctoral Training Program of the University of Wisconsin, Madison. "She was more than my undergraduate professor; she is a teacher from whom I have learned and acquired many skills that have allowed me to succeed in my quest for knowledge."

In her short career, Casillas has received several honors and has been invited to serve as a member on several review panels for agencies such as the National Science Foundation and the United States Department of Agriculture. She has been the main speaker in several local and international conferences and has published more than twenty scientific publications (two in educational journals) and three book chapters. More recently, she was awarded the 2010 Arturo Carrion Lecture Award from ASM's Puerto Rican Chapter for her excellence in teaching Microbiology in Puerto Rico. Casillas is already building a legacy through the achievement and values she instills in her students, as well as her overall impact on the Puerto Rican community.

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To view Dr. Cassillas' biosketch, please visit: http://www.asm.org/index.php/awards-grants/current-carski-foundation-distinguished-undergraduate-teaching-award-laureate.html

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The American Society for Microbiology honors Lilliam Casillas-Martinez

The American Society for Microbiology honors E. Peter Greenberg

Public release date: 6-Jun-2012 [ | E-mail | Share ]

Contact: Garth Hogan ghogan@asmusa.org American Society for Microbiology

Washington, DCJune 6, 2012 E. Peter Greenberg, Ph.D., Professor, Department of Microbiology, University of Washington School of Medicine, has been honored with the 2012 D.C. White Research and Mentoring Award. Recognizing distinguished accomplishments in interdisciplinary research and mentoring in microbiology, this award honors D.C. White, who was known for his interdisciplinary scientific approach and for being a dedicated and inspiring mentor. As stated by his nominator, former graduate student Heidi Kaplan, now at the University of Texas Medical School, "Greenberg's career is marked by outstanding success in what continues to be recognized as interdisciplinary research in quorum sensing. In addition, his mentoring qualities are legendary. He has made an indelible impact on the scientific careers of his students and postdoctoral fellows, and most have gone on to be leaders in microbiology."

Greenberg received his bachelor's in Biology from Western Washington University, and his master's in Microbiology from the University of Iowa. He then went on to the University of Massachusetts, where he earned his Ph.D. in Microbiology. "During that period, Greenberg isolated the first extremophilic spirochete, the salt-loving, vividly red bacterium S. halophila," explained Jared Leadbetter, Caltech. "It was also then that he identified his career-long interest in how bacteria sense the world in which they live, and how they employ such information in behavior and transcription." He next became a NIH postdoctoral Fellow at Harvard University, before joining the faculty at Cornell University and eventually the University of Iowa. In 2005, Greenberg returned to the Pacific Northwest at the University of Washington.

Greenberg has spent his scientific career studying the social behavior of bacteria. He has focused on the coordination of activities in groups of bacteria, with an emphasis on cell-to-cell communication and a phenomenon that is known as quorum sensing. "Greenberg pioneered the quorum-sensing field and has remained one of its leaders. He made a seamless transition from working on bacterial luminescence, a microbiological oddity, to focusing on Pseudomonas pathogenesis, a system that has critical implications on human health," expounded Kaplan. Bacterial communication controls virulence in a variety of pathogenic bacteria, and has thus become a target for the development of new therapeutic strategies. Bacteria have also become models for studies of selection for and evolution of cooperative behavior.

Greenberg's work has been recognized by his election as a Fellow of the National Academy of Sciences, the American Association of Arts and Sciences, the American Association for the Advancement of Science, and the American Academy of Microbiology. "Greenberg's seminal work on quorum sensing and biofilms has revolutionized the way we think about bacterial social behaviors, and the development of 'sociomicrobiology' as a field has impacted virtually every bacteriology researcher in the world," says Marvin Whiteley, University of Texas, Austin. "Greenberg and the students he's mentored reached several important milestones first," adds Leadbetter. "Among them: the first genes cloned from a spirochete, the first evidence for glycosylated proteins in a prokaryote (a highly contentious result at the time that has since proven to be a widespread feature of other bacteria proteins), andperhaps most seminallythe first demonstration in any bacterium of how rotational changes in multiple flagellar motors are coordinated in spirochete cells, ie. through electrical, not chemical, means."

Greenberg's excellence in mentoring has had a lasting impact on his former students, and his valuable guidance has defined the careers of many. "He created an environment that challenged everyone to meet their maximum potential and greatly impact their field," Kaplan said. Whitely summarizes, "Greenberg is an intuitive scientist and encourages creative thinking by his students/post-docs. Importantly, he encourages each individual to follow their interests, whether it be research and/or teaching in academic or industrial settings."

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To view Dr. Greenberg's biosketch, please visit: http://www.asm.org/index.php/awards-grants/current-dc-white-award-laureate.html

The D.C. White Research and Mentoring Award will be presented during the 112th General Meeting of the ASM, June 16 - 19, 2012 in San Francisco, California. ASM is the world's oldest and largest life science organization and has more than 40,000 members worldwide. ASM's mission is to advance the microbiological sciences and promote the use of scientific knowledge for improved health and economic and environmental wellbeing.

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The American Society for Microbiology honors E. Peter Greenberg