Author Archives: ev1

Esteemed Psychiatrist, Pharmacologist and Anti-Aging Physician in Minneapolis, Minnesota Faruk Said Abuzzahab Sr … – MENAFN.COM

Posted on by

(MENAFN Editorial)

The International Association of HealthCare Professionals is pleased to welcome Dr. Faruk Said Abuzzahab Sr., MD, PhD, to their prestigious organization with his upcoming publication in The Leading Physicians of the World. He is a highly-trained psychiatrist, pharmacologist, and anti-aging physician with extensive expertise in all facets of his work. Dr. Faruk Said Abuzzahab Sr. has been practicing for over 57 years and is currently serving patients within Clinical Psychopharmacology Consultants in Minneapolis, Minnesota. He is also affiliated with the University of Minnesota Medical Center.

Dr. Faruk Said Abuzzahab Sr. obtained his Doctor of Medicine Degree from the American University of Beirut in Lebanon in 1959. After completing internship in Beirut, Dr. Abuzzahab Sr. moved to the United States and completed a residency at Johns Hopkins Hospital. He then went on to undertake his Pharmacology fellowship at the University of Minnesota. Additionally, Dr. Abuzzahab also holds a Doctor of Philosophy Degree.

Dr. Abuzzahab Sr. is an internationally renowned expert in the chemistry of the brain, and is a specialist in delaying the aging process in the brain. He maintains a professional membership with the American Academy of Anti-Aging Medicine, and since 2001 has organized annual anti-aging conferences. Dr. Abuzzahab Sr. attributes his success to the examples he gained from his parents and the inspiration they provided him with.

ew Faruk Said Abuzzahab Sr.'s Profile Here: https://www.findatopdoc.com/doctor/8138176-Faruk-Abuzzahab-psychiatrist-Minneapolis-Minnesota-55416

Learn more about Dr. Abuzzahab Sr. by reading his upcoming publication in The Leading Physicians of the World.

About FindaTopDoc.com

FindaTopDoc.com is a hub for all things medicine, featuring detailed descriptions of medical professionals across all areas of expertise, and information on thousands of healthcare topics. Each month, millions of patients use FindaTopDoc to find a doctor nearby and instantly book an appointment online or create a review. FindaTopDoc.com features each doctor's full professional biography highlighting their achievements, experience, patient reviews and areas of expertise. A leading provider of valuable health information that helps empower patient and doctor alike, FindaTopDoc enables readers to live a happier and healthier life. For more information about FindaTopDoc, visit: http://www.findatopdoc.com

SOURCE:International Association of HealthCare Professionals

This press release is distributed by PR NewsChannel. Your News. Everywhere.

MENAFN2803201700703167ID1095353268

Here is the original post:
Esteemed Psychiatrist, Pharmacologist and Anti-Aging Physician in Minneapolis, Minnesota Faruk Said Abuzzahab Sr ... - MENAFN.COM

University of Hawaii, Cardax say study shows anti-aging potential – Pacific Business News (Honolulu)

Posted on by

KHON2
University of Hawaii, Cardax say study shows anti-aging potential
Pacific Business News (Honolulu)
The University of Hawaii's John A. Burns School of Medicine and Honolulu-based life sciences company Cardax Inc. have announced the results of an animal study evaluating the effectiveness of the naturally-occurring chemical astaxanthin that holds ...
Activation of 'longevity gene' could lead to promising anti-aging ...KHON2
Astaxanthin Activates the FOX03 'Longevity Gene'Anti Aging News
Promising anti-aging gene therapy developed through innovative partnershipUH System Current News

all 10 news articles »

Here is the original post:
University of Hawaii, Cardax say study shows anti-aging potential - Pacific Business News (Honolulu)

New Gene Interaction Appears to be Associated with Increased MS … – Independent Tribune

Posted on by

KANNAPOLIS A person could be almost three times more likely to develop multiple sclerosis if they are carrying variants of two particular genes, according to the latest findings from scientists at Duke Health and The University of Texas Medical Branch at Galveston.

The finding, published in the March 23 issue of the journal Cell, could open the way for new tests to identify those at greatest risk of MS and autoimmune disorders, as well as the development of drugs, the researchers said.

The research used biospecimens from the MS cohort of the Measurement to Understand the Reclassification of Disease Of Cabarrus/Kannapolis ( MURDOCK ) Study. The MURDOCK Study is Duke Healths longitudinal clinical research study based at the North Carolina Research Campus in Kannapolis, N.C. The MURDOCK community registry and bio-repository includes more than 12,000 participants and nearly 460,000 biological specimens.

Multiple sclerosis is a major cause of neurological disease in younger adults between the ages of 20 and 50 and disproportionally affects women.

The disease causes the bodys own immune system to attack nerve cells in the spinal cord and brain, causing problems with vision, muscle control, balance and basic body functions. Other symptoms can occur, and could lead to permanent disability.

While treatable, current MS therapies have adverse side effects, as they focus on slowing the progression of the disease through suppression of the immune system. There is no cure for MS.

Our study identifies an interaction with a known MS risk gene to unlock a new MS candidate gene, and in doing so, establishing a novel mechanism that is associated with the risk of multiple sclerosis and other autoimmune diseases, said co-lead author Simon Gregory, Ph.D., director of Genomics and Epigenetics at the Duke Molecular Physiology Institute and principal investigator for the MURDOCK MS Study.

Gregory with colleagues at University of Texas Medical Branch, the University of California, Berkeley, and Case Western Reserve University found two particular DNA variants that appear to play a role in MS. One of these variants is in IL7R, a gene previously associated with MS, and the other in DDX39B, a gene not previously connected to the disease.

When the two are present in a persons genetic code, their interaction can lead to an over-production of a protein called sIL7R. That proteins interactions with the bodys immune system plays an important, but not completely understood, role in MS.

Researchers used MURDOCK biospecimens to examine the chromosomal differences between DDX39B and IL7R.

The researchers said this new information could potentially be used to craft new tests to diagnose multiple sclerosis, or to improve therapeutic toolkits to fight MS and other autoimmune disorders.

One could envision how this type of knowledge will someday lead to diagnose multiple sclerosis sooner and, now that we have promising therapies, a doctor could start the appropriate treatment more quickly. It is not out the realm of possibility to imagine a path for screening for other autoimmune diseases such as Type 1 Diabetes, said co-lead author Mariano Garcia-Blanco, M.D., Ph.D., professor and chair of the Department of Biochemistry and Molecular Biology at University of Texas Medical Branch.

In addition to Gregory and Garcia-Blanco, study authors include lead author Gaddiel Galarza, Farren B.S. Briggs, Irina Evsyukova, Geraldine Schott-Lerner, Edward M. Kennedy, Tinashe Nyanhete, Liuyang Wang, Laura Bergamaschi, Steven G. Widen, Georgia D. Tomaras, Dennis C. Ko, Shelton S. Bradrick and Lisa F. Barcellos.

The research was supported by the National Institutes of Health, National MS Society Pilot Award, Duke University Whitehead Scholarship, Ruth and A. Morris Williams Faculty Research Prize funds from Duke University School of Medicine, start-up funds from University of Texas Medical Branch and funds from Mr. Herman Stone and family for MS research.

Visit link:
New Gene Interaction Appears to be Associated with Increased MS ... - Independent Tribune

Study finds 12 genetic variants that raise the risk of ovarian cancer – Medical News Today

Posted on by

Ovarian cancer is a common form of cancer and a leading cause of cancer death among women. The genes we inherit affect our chances of developing ovarian cancer, and a new genomic study identifies 12 genetic variants associated with the risk.

The Centers for Disease Control and Prevention (CDC) report that almost 21,000 women in the United States were diagnosed with ovarian cancer in 2013, and more than 14,000 died from the disease.

Early detection of ovarian cancer is crucial in improving the patients' survival rate. If the cancer is diagnosed in the early stages - that is, before it has spread beyond the ovaries - the survival rate is estimated at 92 percent. However, according to the American Cancer Society, only 15 percent of ovarian cancers are diagnosed this early.

New research by an international team of scientists from the United Kingdom, the U.S., and Australia identifies 12 genetic variations that raise the likelihood of epithelial ovarian cancer.

Epithelial ovarian cancer (EOC) is the most common type of ovarian cancer. It forms in the epithelium (the tissue) that covers the ovaries.

The results of the new genomic study were published in the journal Nature Genetics.

The new study was conducted as part of the OncoArray Consortium - a large genomic study looking at almost 450,000 samples in an attempt to identify the genetic background for most common cancers.

The OncoArray Consortium used a novel genotyping technique that allowed the researchers to identify nearly 500,000 single nucleotide polymorphisms (SNPs), which are the most common type of variation found in the human genome.

The inherited genetic architecture accounts for a significant portion of a woman's risk of developing EOC, the authors explain.

"We know that a woman's genetic makeup accounts for about one third of her risk of developing ovarian cancer. This is the inherited component of disease risk. We are less certain of environmental factors that increase our risk, but we do know that several factors reduce the risk of ovarian cancer, including taking the oral contraceptive pill, having your tubes tied, and having children."

Prof. Paul Pharoah, co-lead author

Mutations in the BRCA1 and BRCA2 genes make up 40 percent of this risk.

These faulty genes are quite rare - occurring in approximately 1 in 300 people - and correlate with a high incidence of ovarian and breast cancer.

Using data from the OncoArray Consortium, the new study examined the DNA of more than 25,000 people diagnosed with EOC, as well as genetic data from a control group of nearly 41,000 healthy individuals.

Additionally, the researchers investigated more than 31,000 people who had the BRCA1 and BRCA2 genetic mutations, almost 4,000 of whom had EOC.

The researchers located 12 new genetic variants associated with EOC risk. Additionally, the new study confirmed 18 previously identified variants that had been linked to the risk of developing EOC.

Overall, 6.5 percent of the inherited genetic risk of developing EOC is now known.

The first author of the study, Dr. Catherine Phelan from the Moffitt Cancer Center in Tampa, FL, explains what this percentage means:

"Ovarian cancer is clearly a very complex disease - even the 30 risk variants that we now know increase risk of developing the disease account for just a small fraction of the inherited component. We believe that there will likely be many more genetic variants involved, each with extremely small effects. Most of these are likely to be common, but some will be rare."

The authors also note that some women will have multiple risk-associated gene variants, but even combined, these still do not account for more than a 2.8 percent chance of developing ovarian cancer in their lifetimes.

To put this number into perspective, patients who are offered the option to have their ovaries surgically removed as a preventive measure most often have a lifetime risk of at least 10 percent.

However, the researchers also note that a combination of these genetic variants and being a carrier of the faulty BRCA1 and BRCA2 genes might sometimes be enough to call for preventive surgery.

"In some ways, the hard work starts now. We really have little idea of the functional effect these variants have at the molecular or cellular level and so there are few clues as to how they might affect risk. If we can understand how they work, we will be in a better position to treat - and possibly prevent - ovarian cancer."

Dr. Simon Gayther, study co-author

Learn how tumor DNA fragments help to predict ovarian cancer outcomes.

More:
Study finds 12 genetic variants that raise the risk of ovarian cancer - Medical News Today

Purification of Pharmaceutical and Biotechnology Products with Kromasil EternityXT Stationary Phase – Labmate Online

Posted on by

With excellent mechanical and chemical stability, the Kromasil EternityXT materials offer first-rate separation power and loadability for purification from low to high pH. Kromasil EternityXT C8 and C18 materials can operate up to pH 12, making it possible to run basic compounds under extreme conditions to improve purification productivity and reduce costs. These products support discovery, development and production departmental goals in the purification of a low molecular weight pharmaceuticals, peptides and biotechnology products.

The exceptional structure of Kromasil EternityXT C18 and C8 materials makes it possible to regenerate the material in-column, carrying out cleaning in place (CIP) even at 1 M NaOH, if so required. While this high concentration NaOH treatment is a standard in bio chromatography and until now only conceivable with polymer resins, Kromasil EternityXT materials open up the spectrum of purification options as its C8 and C18 materials resist up to 1 M NaOH.

Read the rest here:
Purification of Pharmaceutical and Biotechnology Products with Kromasil EternityXT Stationary Phase - Labmate Online

Agricultural Biotechnology: Emerging Technologies and Global … – Yahoo Finance

Posted on by

NEW YORK, March 27, 2017 /PRNewswire/ -- Use this report to:- Analyze existing and future agricultural biotechnology products and technologies that will be commercially important. - Receive a qualitative and quantitative description of the agricultural biotechnology industry. - Highlight key market and industry trends, as well as quantify the main market segments. - Receive information on agricultural biotechnologies, market applications, industry structure and competitive dynamics.

Highlights- The global market for agricultural biotechnology reached $29.2 billion in 2016. This market should reach $32.1 billion in 2017 and $53.7 billion in 2022, with a compound annual growth rate (CAGR) of 10.8%. - Genomic-enabled products as a segment reached $24.1 billion in 2016, and should reach nearly $26.5 billion in 2017 and $43.7 billion in 2022, with a CAGR of 10.6%.

STUDY GOALS AND OBJECTIVES BCC Research's goal for this study is to determine the specific applications and forecast global market demand for agricultural biotechnology products over a five-year period from 2017 through 2022. The main objective is to characterize and quantify the agricultural biotechnology products market by product type, geography, and purpose. In addition, the report analyzes the industry structure, competitors, strategic alliances, and intellectual property landscape. A total of 70 companies in the industry are profiled.

Agricultural biotechnology markets analyzed in this report include biotechnology tools, genomics enabled products, and biologicals. Biotechnology tools include DNA sequencing, biochips, RNA interference, synthetic biology, and genome editing. Genomics enabled products include biotech seeds and synthetic biology-enabled products. Biologicals include biopesticides, biostimulants, and genetic biologicals.

A key objective of the report is to provide a comprehensive analysis of the agricultural biotechnology industry, with an emphasis on products and technologies that are commercially important in the 2017 to 2022 time-period. Market segments with rapid growth rates are highlighted, as well as those segments with large market potential. This analysis provides a quantitative basis and market context for companies to make strategic choices about participation in the agricultural industry.

The study will be particularly useful to those companies developing new genomics or proteomics technologies; discovering and development novel seed traits; doing plant breeding; interested in using novel biotechnologies in agriculture; or working inadvanced biotechnology fields like genome editing, synthetic biology, RNA interference, biochips, or DNA sequencing.

The study will also be useful to government agencies or institutions that are developing strategic initiatives for a country's agriculture policy and/or industry.

REASONS FOR DOING THE STUDY

Agriculture is a fundamental and strategic component for a country. As a result, agricultural technologies provide competitive geographic advantage and are highly desirable. Biotechnologies address the pressing industry need for higher crop yields. Agricultural biotechnology is a key and growing component of the global agriculture industry and is thus of interest to a wide audience.

This report seeks to provide a qualitative and quantitative description of the agricultural biotechnology industry so that emerging market opportunities can be identified and exploited by the reader.

The report does this by examining the main product applications and markets, helping companies to prioritize product opportunities and strategic opportunities. The report highlights key market and industry trends, as well as quantifying the main market segments. The reader is thus able to better understand industry structure and changes occurring in the industry.

Rapid changes in technology-intensive fields such as DNA sequencing, genome editing, and synthetic biology are driving new products and applications in agriculture. These developments create unique market opportunities. This report analyzes these trends and their impact on future markets for agricultural products.

Based on these market and technology dynamics, it is especially timely to examine the agricultural biotechnology industry.

INTENDED AUDIENCE

Read More

This study examines and analyzes existing and future agricultural biotechnology products and technologies that will be commercially important.

Markets are presented by product type, crop type, and geographical region. Important market segments covered include the main biotechnologies (DNA sequencing, biochips, RNA interference, synthetic biology tools, and genome editing tools) as well as synthetic biology-enabled chemicals and biofuels, biotech seeds, and biologicals.

In-depth coverage is provided for agricultural biotechnologies; growth driving forces; market applications; industry structure and competitive dynamics; companies and industry alliances; future market potential and product sales forecasts for the period 2017 through 2022. The report forecasts the future value of agricultural biotechnology products by product type and geography.

This report will be of particular interest to agriculture, chemicals, bio-energy, and biotechnology companies; as well as suppliers of genomics tools, synthetic biology, RNA interference, and DNA sequencing products. It will also be of interest to professionals within governments, think tanks, and regulatory agencies to understand the end uses of these technologies in agriculture.

SCOPE AND FORMAT

The study scope includes key agricultural biotechnology tools (i.e., next generation DNA sequencing, biochips, RNA interference, synthetic biology tools and genome editing tools); synthetic biology-enabled chemicals and biofuels; biotech seeds; and biologicals.

BCC analyzes these technologies and products to determine present and future market sizes, and forecasted growth from 2017 through 2022. The report also discusses industry strategic alliances, industry structures, competitive dynamics, patent status, and market driving forces.

BCC provides in-depth coverage of the agricultural biotechnology industry structure, including genomics technology providers (e.g., genome editing, NGS, microarray companies); major seed companies; biotech traits companies; synthetic biology tools companies; companies developing plant feedstocks; and agricultural biologicals companies. It provides an in-depth analysis of major industry acquisitions and alliances during 2015 and 2016.

70 agricultural and biotechnology companies are profiled in this report.

METHODOLOGY

BCC Research examined key users and producers in each of the enduser market segments and technology fields that will be commercially important during the next five years. Discussions with industry thought leaders, as well as secondary market research was performed.

Based on our analysis, we project the future applications of agricultural biotechnologies in the major enduser market segments and by technology type, and forecast sales revenues for 2017 through 2022.

INFORMATION SOURCES

BCC Research performed primary and secondary research for this report. Primary sources included key industry companies and leading research institutions. In addition, data were compiled from secondary sources, including company websites and industry, trade and government publications. Read the full report: http://www.reportlinker.com/p0958100-summary/view-report.html

About Reportlinker ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

http://www.reportlinker.com

__________________________ Contact Clare: clare@reportlinker.com US: (339)-368-6001 Intl: +1 339-368-6001

To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/agricultural-biotechnology-emerging-technologies-and-global-markets-300429907.html

Continue reading here:
Agricultural Biotechnology: Emerging Technologies and Global ... - Yahoo Finance

FDA approves first-in-human trial for neural-enabled prosthetic hand system developed at FIU – Medical Xpress

Posted on by

March 29, 2017 by Jennifer Lacayo Credit: Florida International University

Upper extremity amputees are one step closer to successfully picking up a cookie or an egg, thanks to a new advanced prosthetic system that is designed to restore sensation.

The U.S. Food and Drug Administration (FDA) has granted an investigational device exemption for the first-in-human trial with this technology. The system was developed at Florida International University by Ranu Jung and her Adaptive Neural Systems Laboratory team.

"The system is intended to restore the sense of touch, and hand opening which would allow users to precisely differentiate the size and fragility of various objects," said Ranu Jung, interim dean of the College of Engineering and Computing and a Wallace H. Coulter Eminent Scholars Chair in biomedical engineering. "The prostheses that exist today make it difficult for amputees to manipulate delicate and small objects because they can't feel them."

Jung's technology, a neural-enabled prosthetic hand system (NEPH), stimulates nerves in the arm to provide sensation as the person is using the prosthetic hand. The prosthetic system has the first fully implantable, wirelessly controlled Class-III device with electrodes that can be surgically implanted within the nerves of the residual arm.

The video will load shortly

"The system reflects an almost decade-long collaborative team effort. For the first time, amputees will be able to use a fully implantable, sensory enabled prosthetic hand system at home for daily activities and researchers will be able to assess the long term clinical impact of its use in real-world environments," said Jung.

Similar to a pacemaker, the system works by delivering small electrical pulses to specific nerves in the arm. Wires as thin as a hair strand are placed within nerve bundles in the arm and connected to an electrical stimulator. Sensors embedded in the prosthetic hand send signals wirelessly to the implanted stimulator, which then elicits sensation by delivering weak electrical pulses via the implanted electrodes. As a result, the person should be able to sense their hand opening position and grip items when the prosthetic hand encounters an object.

Participants in the trial will be able to use the system outside of the laboratory on a daily basis. At this time, the NEPH system is not approved by the FDA for U.S. commercial distribution, but if this first-in-human trial is successful, Jung and her team plan to continue testing through larger clinical trials and eventually seek such approval.

The system can potentially be interfaced with several different advanced prosthetic hands that are currently being developed commercially or under government support. Jung has spent the last decade developing the prosthetic hand system with the assistance of a Bioengineering Research Partnership grant from the National Institutes of Health (NIH), specifically its National Institute of Biomedical Imaging and Bioengineering (NIBIB) and Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD).

"This research journey started from foundational neuroscience and engineering principles to incorporating with painstaking accuracy the validation needed to make this system ready for clinical studies and this first-in-human trial. This unique system, integrating the long-term efforts of academia and industry, is an example of the bioengineering partnerships we promote," said Grace Peng, Ph.D., Program Director at NIBIB.

The HAPTIX program of the Defense Advanced Research Projects Agency (DARPA), which is an agency of the Department of Defense, is now supporting the first-in-human trial of the system. Florida International University, with Jung as principal investigator, will receive up to $2.2 million in support of this first-in-human trial.

Explore further: New prosthetic invention lets users reclaim their sense of touch

Two years ago, Melissa Loomis, age 43, was in her house in Ohio when she heard her two dogs barking and scuffling outside. She discovered her pets in a tussle with a raccoon and ran to intercede. The wild animal bit her right ...

Scientists have developed sensor technology for a robotic prosthetic arm that detects signals from nerves in the spinal cord.

When someone loses a limb to war, accident, or disease, she can get an artificial limb that restores some of her lost movement. But even the best prosthesis doesnt restore the sense of touch. And touch is what lets ...

In a study recently published in IEEE Transactions on Neural Systems and Rehabilitation Engineering, neurobiologists at the University of Chicago show how an organism can sense a tactile stimulus, in real time, through an ...

Walking through a busy store, Keith Vonderhuevel confidently held his 5-year-old granddaughter's hand with his prosthetic hand. Feedback in the form of electrical pulses that mimic pressure, told him how intensely he grasped ...

Using PET scans of the brain, University of Michigan researchers showed that dopamine falls and fluctuates at different times during a migraine headache.

A newly approved drug that is the first to reflect the current scientific understanding of multiple sclerosis (MS) is holding new hope for the hundreds of thousands Americans living with the disease.

With more than 130,000 victims nationwide, strokes are among the leading causes of death in the U.S. each year. According to the Centers for Disease Control (CDC), someone in the United States has a stroke every 40 seconds, ...

After a baby is born, a souvenir of its months in the womb is usually not long to follow. Its first poo, or meconium, is a lump sum of everything the foetus has ingested for months; a dark sludge, compared by the insomniac ...

New research from scientists at the University of Sussex has taken a major step towards unlocking the secrets of hypnosis and gathering evidence that suggests that subjects aren't faking the effects of it.

A drug developed during World War II as an antidote for a chemical warfare agent has been found to be effective at suppressing a neurotoxin that worsens the pain and severity of spinal cord injuries, suggesting a new tool ...

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

View original post here:
FDA approves first-in-human trial for neural-enabled prosthetic hand system developed at FIU - Medical Xpress

Grey’s Anatomy’s Chandra Wilson Opens Up About Her Daughter’s … – PEOPLE.com

Posted on by

Eurweb.com
Grey's Anatomy's Chandra Wilson Opens Up About Her Daughter's ...
PEOPLE.com
As Dr. Miranda Bailey on ABC's Grey's Anatomy, Chandra Wilson is used to solving medical mysteries. But when her daughter suddenly came face to face with ...
Actress Chandra Wilson On Daughter's Cyclic Vomiting Syndrome ...MadameNoire

all 3 news articles »

Go here to read the rest:
Grey's Anatomy's Chandra Wilson Opens Up About Her Daughter's ... - PEOPLE.com

How to Craft the Perfect Cheese Plate – Skillet – Lifehacker – Lifehacker

Posted on by

Illustration by Sam Woolley.

A cheese plate can be many things. A party platter, a snack, even a meala cheese plate can all of these things and more. It doesnt require any cooking, but crafting a perfectly harmonious plate of delicious dairy is a delicate balancing act, and some forethought is required.

It can be easy to go overboard with both cheeses and accouterments, but having a clear vision of the type of cheese plate you want to present to the world can keep you on track. But before you can do that, you need to decide how many cheeses you want to serve.

There are two routes you can take when presenting one cheese. You can choose a crowd-pleaserlike a good sharp cheddar or an excellent wheel of brieor you can go with a slightly more divisive show-stopper like a super funky blue, or the stinky-though-tasty Taleggio. In either case, youll need at least one carby delivery system and one complementary extra. Serious Eats has a good primer on various tasty types of cheese, but here are a few of my favorite ways to let a single cheese shine:

Another good way to focus on one cheese is to bake it or marinate it. Baked brie en croute, goat cheese with tomato sauce, and marinated mozzarella or feta all make great cheesy centerpieces.

Im not a fan of the even-numbered cheese plate for some reason, but if you are only going to serve two cheeses, I would do one hard and one soft, and do them really well. Three is my favorite number to serve however, because it gives you the freedom to throw something wild and crazy into the mix. Here are some of my favorite picks for each category:

To ensure a good variety of flavors, you can try picking one from each cheese-bearing animal (cow, sheep, goat), but Ive used my hard, soft, fun template with much success. (That template seems much dirtier than it actually is, now that Ive typed it out.)

Now that we have our cheeses chosen, were free to think about fun add-ons. It can be very easy to go crazy here, so I try to limit myself to one sweet thing, one salty thing, one sweet saucy thing, and one savory saucy thing. Youll also need bread and crackers.

I know thats a lot of foodie info to take in at once, so well recap real quick: unless you are going the one cheese route we covered earlier, my platonic ideal of a cheese plate is:

1 hard cheese + 1 soft cheese + 1 fun cheese

Served on:

simple toasted toast points + a smattering of seedy or fruity crackers

Paired with:

1 sweet thing + 1 salty thing + 1 sweet saucy thing + 1 salty saucy thing

This may seem like a lot, but Ive never had much in the way of leftovers and, if the unthinkable does happen you are plagued by excess cheese, you can always make cheese crisps or fromage fort. Everyone wins.

Read the original post:
How to Craft the Perfect Cheese Plate - Skillet - Lifehacker - Lifehacker

John’s book discovery suggests taboo hindered knowledge of female anatomy – Varsity Online

Posted on by

A diagram of female genitalia in the 16th-century work was censored, presumably by its original owner

St John's College has acquired a sixteenth-century anatomy book which researchers at the University say indicates that taboo hindered the development of scientific knowledge about the female anatomy.

Theedition of Thomas Geminis book Compediosa Totius Anatomie Delineatio,dating to 1559, has been subject to much academic attention, asit features an example of censorship by its owner, suggesting that scientific investigation into the female anatomy was hindered by a cultural aversion to female sexuality.

The book depicts a semi-dissected female torso, with a triangle of paper cut away, presumably by the original owner, from where the female genitals would have been. Curator Shelley Hughes suggested that the owner was disturbed by the offending part of Geminis depiction.

Subject sexism: unconscious stereotypes

"Sin and female flesh were held in close association in 16th century society with naked women often portrayed as the servants of Satan, Hughes told the Cambridge News.

"Perhaps Christian Europe would have to overcome its shame over the female reproductive organs in order to discover more about their structure."

Her sentiments echo the general purpose of the exhibition - to map the development of medical knowledge as the religious sentiments which impeded human dissection and asserted female biological inferiority gradually faded.

The book was featured in an exhibition named Under the Knife At St Johns: A Medical History Of Disease And Dissection on Saturday 25th at St Johns College, which traced medical breakthroughs from as early as the 13th century through pieces from the College Librarys Special Collections

See original here:
John's book discovery suggests taboo hindered knowledge of female anatomy - Varsity Online

Cardax Astaxanthin Compound CDX-085 Stimulates Anti-Aging … – Business Wire (press release)

Posted on by

HONOLULU--(BUSINESS WIRE)--Cardax, Inc. (Cardax) (OTCQB:CDXI) and the University of Hawaii (UH) announced today that Cardaxs proprietary astaxanthin compound, CDX-085, demonstrated an almost 90% increase in FOXO3 gene expression in mice (p=0.024).

This research was conducted by UH scientists Dr. Bradley Willcox, M.D., Professor and Director of Research at the Department of Geriatric Medicine, John A. Burns School of Medicine, University of Hawaii (JABSOM) and Principal Investigator of the NIH-funded Kuakini Hawaii Lifespan and Healthspan Studies, and Dr. Richard Allsopp, Ph.D., Associate Professor, Institute of Biogenesis Research at JABSOM.

Previously in humans, Dr. Willcox and colleagues discovered genetic variants of FOXO3 in humans that protect against aging (Willcox et al. Proc US Natl Acad Sci 2008).

This observation has since been replicated in >20 independent studies. At the American Heart Association Meeting in 2015, it was announced that the protective FOXO3 allele is strongly associated with reduced coronary heart disease mortality (p=0.00001) (AHA Meeting 2015) and later published in the leading gerontology journal (Willcox et al. J Gerontol Biol Med Sci 2016).

These results augment earlier findings in the C. elegans roundworm, a well-accepted model of aging, said Dr. Allsopp, where astaxanthin extended lifespan by 16-30%.

All of us have the FOXO3 gene, which protects against aging in humans, said Dr. Willcox. But about one in three persons carry a version of the FOXO3 gene that is associated with longevity. By activating the FOXO3 gene common in all humans, we can make it act like the "longevity" version. Through this research, we have shown that astaxanthin activates the FOXO3 gene.

This exciting new evidence provides yet another reason for physicians and patients to consider an astaxanthin dietary supplement such as ZanthoSyn as the foundation of an anti-aging, longevity program, said David G. Watumull, Cardax CEO.

About CDX-085

CDX-085 is the patented active ingredient of Cardaxs second generation product and like its first generation dietary supplement, ZanthoSyn, delivers astaxanthin to the blood stream with excellent absorption and purity, but in a more concentrated form, allowing higher doses per capsule and improved dosing convenience. Astaxanthin is a safe anti-inflammatory for general health that supports anti-aging and longevity.*

About FOXO3

FOXO3 is a member of the forkhead family of transcription factors. The human homolog in C. elegans, daf-16, has profound effects on longevity (Kenyon et al. A C. elegans mutant that lives twice as long as wild type. Nature 1993). Scientists led by Dr. Bradley Willcox, MD, member of the Cardax scientific advisory board, discovered a genetic variant of FOXO3 in humans that protects against aging (Willcox et al. Proc US Natl Acad Sci 2008). This observation has since been replicated in >20 independent studies. The protective FOXO3 allele (G allele) is associated with longevity with one G allele (GT genotype) doubling the odds to live to 100 and two G alleles (GG genotype) tripling the odds to live to 100. The protective FOXO3 allele is strongly associated with reduced coronary heart disease mortality (p=0.00001) (Willcox et al. AHA Meeting 2015) and the protective FOXO3 allele is strongly associated with reduced serum inflammatory markers (CRP and TNF-).

About Cardax

Cardax devotes substantially all of its efforts to developing and commercializing safe anti-inflammatory dietary supplements and drugs. Cardax is initially focusing on astaxanthin, which is a powerful and safe naturally occurring anti-inflammatory without the side effects of currently marketed anti-inflammatories. The safety and efficacy of Cardax's products have not been directly evaluated in clinical trials or confirmed by the FDA.

Safe Harbor

This release may contain certain forward-looking statements regarding our prospective performance and strategies within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. We intend such forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995, and are including this statement for purposes of said safe harbor provisions. Forward-looking statements, which are based on certain assumptions and describe future plans, strategies, and expectations of our company, are generally identified by use of words anticipate, believe, estimate, expect, intend, plan, project, seek, strive, try, or future or conditional verbs such as could, may, should, will, would, or similar expressions. Our ability to predict results or the actual effects of our plans or strategies is inherently uncertain. Accordingly, actual results may differ materially from anticipated results. Some of the factors that could cause our actual results to differ from our expectations or beliefs include, without limitation, the risks discussed from time to time in our filings with the Securities and Exchange Commission. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this release. Except as required by applicable law or regulation, we undertake no obligation to update these forward-looking statements to reflect events or circumstances that occur after the date on which such statements were made.

More:
Cardax Astaxanthin Compound CDX-085 Stimulates Anti-Aging ... - Business Wire (press release)

EXCLUSIVE: Sharna Burgess and Bonner Bolton Talk Explosive Chemistry on ‘DWTS,’ Avoiding Another Handgate – Entertainment Tonight

Posted on by

Playing EXCLUSIVE: Sharna Burgess and Bonner Bolton Talk Explosive Chemistry on 'DWTS,' Avoiding Another Handgate

It's no secret that Dancing With the Stars pair Sharna Burgess and Bonner Bolton look pretty great together, on and off the dance floor.

The 31-year-old dancing pro and the 29-year-old bull rider have had all eyes on them this season, thanks to their explosive chemistry, which doesn't show any signs of stopping soon. On Sunday, Burgess shared a steamy pic of her and Bolton getting super close, previewing their upcoming waltz on Monday's show.

"It's been one heck of a week for @bonner_bolton and I, to be honest... kinda stressful," she wrote. "However, all the controversy aside I have to tell you... this cowboy can waltz!!! He tells me it's because it reminds him of the Texas two step... so this dance is inspired by exactly that and the culture surrounding it. He's worked his butt off and is on track to kill it tomorrow. Get ready for it loverz."

NEWS: 'DWTS' Week 2 Preview -- Sharna Burgess & Bonner Bolton Turn Up the Heat, Maksim Chmerkovskiy Injured & More!

Burgess' "controversy" mention is, of course, referring to the pair's unintentional viral moment last week, when backstage cameras caught Bolton wrapping his arm around Burgess and his hand going quite a bit lower than her waist. ET's Cameron Mathison caught up with the duo at their DWTS rehearsals on Friday, where Bolton explained how he's going to avoid another mishap.

"It got a lot of attention, that's for sure," Bolton told ET. "I'm definitely going to be more cautious of where my hands are."

"Obviously, I don't know what to do with my hands," he joked, before getting serious. "It's really .. it was so unintentional and I have all the respect on and off the dance floor for this young lady, so it's totally cool."

"We're good," Burgess confirmed. "It's alright."

The pair also acknowledged their obvious spark. The two bonded early on when Bolton took Burgess out for Cajun food on the first day they met in Texas.

"We have a great chemistry getting to know each other, but obviously we're three weeks into this thing of having met each other on his ranch, and we're having a lot of fun, but our priorities obviously are getting Bonner through this competition as far as he can possibly go," Burgess said. "So, in the meantime, we're having a lot of fun getting to know each other and we do have great chemistry."

"She's really good to get along with," Bolton added of his partner. "We actually have a lot in common, I think, in that our personalities are real similar, but that can make it kind of challenging. Sometimes, I think, I get on her nerves a little bit."

Still, Bolton didn't shut the door on a future romance between them when asked if he would ever date Burgess.

"I'm gonna have to see where that one goes, and take that into consideration, but we'll just leave that a mystery," he said.

WATCH: EXCLUSIVE -- 'DWTS' Partners Sharna Burgess and Bonner Bolton Reveal Whether They Are Still Single

On Sunday, Bolton Instagrammed that he's feeling good about Monday's waltz.

"I hope it touches everyone's heart and that you all enjoy it as much as I enjoy dancing to it! #vote #teamdenimndiamonds," he wrote, alongside a cute picture of him with his arm around Burgess.

Watch the video below to see Bolton and Burgess' flirty night out at the Cowboy Palace Saloon in Chatsworth, California, last Tuesday.

See more here:
EXCLUSIVE: Sharna Burgess and Bonner Bolton Talk Explosive Chemistry on 'DWTS,' Avoiding Another Handgate - Entertainment Tonight

Middle school student qualifies to state chemistry challenge – Hudson Hub-Times

Posted on by

By TIM TROGLEN Reporter Published: March 29, 2017 12:00 AM

HUDSON -- A team of six Hudson Middle School students competed in the March 4 'You Be the Chemist' challenge at Great Lakes Science Center.

Hudson Middle School students qualifying for the competition included: Quinn Berichon, William Carvahlo, Hannah Ma, Carl Roessler, Thomas Banko and Andrew Constable.

One of those students, Thomas Banko, finished second and will move on to the state competition in April.

The middle school team faced teams from Harding Middle School in Lakewood, Wilcox Elementary in North Ridgeville, Lewis F. Mayer Middle School in Fairview Park, Albert Einstein Academy in Westlake, Menlo Park Academy in Cleveland and North Ridgeville Middle School.

The challenge, sponsored by Palmer Holland a national chemical distributor located in North Olmsted, was open to all Hudson Middle School students. However, the students had to qualify via a written exam, according to science teacher Rebecca Reese.

A total of 28 students initially qualified. After several sessions and a second test, the top six made the team and competed March 4, according to Reese.

"Students answered questions based on chemistry concepts," Reese said. "We competed against four other schools in the greater Cleveland area."

Each of the six students was given a T-shirt for participating.

The program was introduced to the district by Hudson parent Ron Zmich, an employee of Palmer Holland who has been working with the students on science-based enrichment activities.

"The YBTC Challenge is an interactive academic competition for fifth-through-eighth grade students focusing on chemistry concepts, history and safety...a Chemistry Academic Challenge, if you will," Zmich said. "The program begins with a local county challenge and progresses to a state challenge and finally a national challenge."

Palmer Holland took over as organizer/administrator of the You Be The Chemist Challenge initiative five years ago according to Zmich, executive advisor for the Greater Cleveland Local Challenge effort.

"The challenge is promoted by the Chemical Education Foundation for both Cuyahoga and Summit counties."

Zmich said the challenge is an electronic question/answer competition that engages students in grades fifth through eighth in learning about important chemistry concepts, historical discoveries and chemical safety. Free study materials are provided by the Chemical Educational Foundation to help students prepare for the challenge, he added.

"As an industry sponsor of the program, Palmer Holland covers all registration fees for those students participating in the local, state and national challenges," Zmich said. "Similar in format to the National Spelling Bee, the top three places from our local challenge move on to the Ohio state challenge."

The winner of the state challenge will progress to the national challenge to be held in Washington D.C. in June.

"Prizes are awarded to winners at all phases of the challenge," Zmich said. "The national champion will win prizes and a scholastic scholarship of $10,000."

Email: ttroglen@recordpub.com

Phone: 330-541-9435

Twitter: @Trog_RPC

Visit link:
Middle school student qualifies to state chemistry challenge - Hudson Hub-Times

Buy, Sell or Hold? Analysts Approach: Innoviva (INVA), Puma … – The USA Commerce

Posted on by
Buy, Sell or Hold? Analysts Approach: Innoviva (INVA), Puma ...
The USA Commerce
Shares of Puma Biotechnology, Inc. (NASDAQ:PBYI) dropped -2.02% to $38.90. During the trading on 03/27/2017, Company's stock ranged from $39.70 to ...
Puma Biotechnology Inc (NASDAQ:PBYI) Broker Price Targets For ...Fiscal Standard

all 3 news articles »

Excerpt from:
Buy, Sell or Hold? Analysts Approach: Innoviva (INVA), Puma ... - The USA Commerce

Scientist maps giant virus – Phys.org – Phys.Org

Posted on by

March 28, 2017 by Layne Cameron Kristin Parent mapped the structure of the giant Samba virus with MSU's cryo-EM microscope, which is featured on the cover of the journal Viruses. Credit: Michigan State University

In a laboratory at Michigan State University, scientists took a DIY approach to build a retrofitted cryo-electron microscope that allowed them to map a giant Samba virus one of the world's largest viruses.

"If the common cold virus is scaled to the size of a ladder, then the giant Samba virus is bigger than the Washington Monument," said Kristin Parent, assistant professor of biochemistry and molecular biology and co-author of the paper featured on the cover of the journal Viruses. "Cryo-EM allowed us to map this virus' structure and observe the proteins it uses to enter, or attack, cells."

It seems counterintuitive that bigger organisms are harder to see, but they are when using cryo-electron microscopy. That's because these microscopes usually are used to look at thin specimens and can't decipher larger organisms to reveal their biological mechanisms. For thick samples, scientists see only dark gray or black blobs instead of seeing the molecular framework.

Cryo-EM allowed Parent's team to image the giant Samba virus and understand the structures that allow it to enter an amoeba. Once inside, Samba opens one of its capsid layers and releases its nucleocapsid which carries the genetic cargo that sparks an infection. While Samba isn't known to cause any diseases in humans, its cousin, the mimivirus, may be a culprit for causing some respiratory ailments in humans.

"If you scoop up a handful of water from Lake Michigan, you are literally holding more viruses than there are people on the planet," said Parent, who published the paper with Jason Schrad and Eric Young, MSU biochemistry and molecular biology graduate students. "While scientists can't study every virus on Earth, the insights we glean from viruses like the giant Samba can help us understand the mechanisms of other viruses in its family, how they thrive and how we can attack them."

As bacteria become more resistant to antibiotics, looking for new ways to fight diseases will continue to grow in importance. Parent's lab also studies how bacteria-infecting viruses enter cells using this method, which could potentially lead to new antibacterial treatments. Yet the world's best cryo-EM microscope costs more than $5 million. Limited by funds but not drive, Parent was able to upgrade an existing microscope at MSU to do cryo-EM one that is a tinkerer's dream.

This traditional transmission electron microscope was retrofitted with a cryostage, which keeps viruses frozen in liquid nitrogen while they're being studied. Parent and her team then added a Direct Electron DE-20 detector, a powerful camera the mighty microscope's piece de resistance.

Parent didn't invent cryo-EM, but establishing it on campus serves as a viable proof-of-concept for MSU, opening the door for many interdisciplinary partnerships. This cutting-edge microscopy has applications across many fields, from those addressing a single protein to others studying entire cells. Virtually anyone studying complex molecular machines can advance their work with this tool, Parent added.

Parent has earned an AAAS Marion Milligan Mason Award for Women in the Chemical Sciences. This award, her paper in Viruses and being the co-author who performed cryo-EM work in a recent Nature Communications paper, lays the groundwork to some day have a more advanced cryo-EM microscope housed at MSU to be able to perform high-resolution structural studies.

"We've done quite a bit with our limited resources, but we're primed to do more," Parent said. "I think MSU could serve as a cryo-EM center and to increase the prevalence of this technology in the Midwest and beyond."

As one example, scientists from Universidade Federal de Minas Gerais (Brazil) and Universidade Federal do Rio de Janeiro (Brazil) also contributed to this study and benefitted from the technology MSU has to offer.

Explore further: Cryo-electron microscopy achieves unprecedented resolution using new computational methods

Cryo-electron microscopy (cryo-EM)which enables the visualization of viruses, proteins, and other biological structures at the molecular levelis a critical tool used to advance biochemical knowledge. Now Lawrence Berkeley ...

Advances in both light and electron microscopy are improving scientists' ability to visualize viruses such as HIV, respiratory syncytial virus (RSV), measles, influenza, and Zika in their native states. Researchers from Emory ...

Scientists at Baylor College of Medicine, the Lawrence Berkeley National Laboratory, Massachusetts Institute of Technology and Purdue University have completed a model of unprecedented near-atomic resolution of the chemical ...

An international group of scientists have solved the atomic structure of the Ljungan virus, an infection of rodents that is also associated with a variety of dangerous diseases in humans, including diabetes, neurological ...

Since the discovery of the microscope, scientists have tried to visualize smaller and smaller structures to provide insights into the inner workings of human cells, bacteria and viruses. Now, researchers at the National Institute ...

Next-generation steel and metal alloys are a step closer to reality, thanks to an international research project involving a University of Queensland scientist.

A fluorescent probe developed by Michigan Tech chemist Haiying Liu illuminates the enzyme beta-galactosidase in a cell culture, which could help cancer surgeons.

In order for a fuel cell to work, it needs an oxidizing agent. TU Wien has now found a way to explain why oxygen does not always enter fuel cells effectively, rendering them unusable.

Researchers at the University of York and Simon Fraser University, Canada, revealed the 3-D structure of an enzyme that could provide a crucial step forward in treating neurodegenerative diseases.

The photodissociation of triiodide anion (I3-) is a classic textbook reaction that has been extensively studied both in solution and in gas phase. However, probing the ultrafast dynamics of this reaction in the solid state ...

A study published today shows how Indiana University scientists are speeding the path to new treatments for the Zika virus, an infectious disease linked to birth defects in infants in South and Central America and the United ...

Opioids have long been an important tool in the world of pain management, but the side effects of these drugs - from addiction and respiratory failure to severe itching and dizziness, can be overwhelming. Scientists have ...

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Continue reading here:
Scientist maps giant virus - Phys.org - Phys.Org

Grey’s Anatomy Stars Name Their Favorite TV Doctors – Today’s … – TV Guide (blog)

Posted on by

Now Playing The Stars of Grey's Anatomy Reveal Their (Other) Favorite TV Doctors

The staff members at Grey Sloan Memorial Hospital on Grey's Anatomy are part of a long history of fictional doctors on television, from Hawkeye to House. But which of their onscreen predecessors provided "career inspiration" for the stars of Grey's?

We asked the cast, who were on hand at PaleyFest in Los Angeles, to name their favorite TV docs -- and while a few of the usual suspects (ahem, George Clooney's ER pediatrician, Dr. Doug Ross) made the cut, a few of their other choices may surprise you.

And don't be fooled -- while these guys may not be performing actual surgeries, they still have to learn all that real-life medical jargon, which is not an easy task.

Check out the video to see which (fake) MDs Chandra Wilson, Jerrika Hinton, Jason George and more cast members from Grey's Anatomy admire the most -- aside from their own colleagues, of course.

Grey's Anatomy airs Thursdays at 8/7c on ABC.

Read more:
Grey's Anatomy Stars Name Their Favorite TV Doctors - Today's ... - TV Guide (blog)

University of Hawaii, Cardax say study shows anti-aging potential – Pacific Business News (Honolulu)

Posted on by

Pacific Business News (Honolulu)
University of Hawaii, Cardax say study shows anti-aging potential
Pacific Business News (Honolulu)
The University of Hawaii's John A. Burns School of Medicine and Honolulu-based life sciences company Cardax Inc. have announced the results of an animal study evaluating the effectiveness of the naturally-occurring chemical astaxanthin that holds ...
Activation of 'longevity gene' could lead to promising anti-aging therapyKHON2
Promising anti-aging gene therapy developed through innovative partnershipUH System Current News
Cardax, Inc. (CDXI: OTCQB) | Cardax Astaxanthin Compound CDX-085 Stimulates Anti-Aging Gene in MiceMilTech

all 6 news articles »

Read more:
University of Hawaii, Cardax say study shows anti-aging potential - Pacific Business News (Honolulu)

Anti-aging – Curacao Chronicle

Posted on by

A 35-year-old overweight lady caused some commotion at the check-out counter of a supermarket when she tried to pay for a few bottles of antioxidants with a Food Stamps Debit Card. Antioxidants? Do they still exist? What happened to them?

"The fountain of youth is discovered," touted the media with great fanfare somewhere in the early 90's. Only, one daily dietary supplement would stop aging. A eureka moment made famous scientists, Rebeca Gerschman, Denham Harman and others, realize the importance of oxygen leaks deep down in tiny cell particles, mitochondria, as the destructive force, which causes aging and death.

Free radical (O and OH) were capable of damaging proteins, mutating DNA and initiate long, deadly chain reactions, ultimately creating a crescendo of destruction, culminating in an error catastrophe, that ultimately caused apoptosis or cell death.

If free radicals were bad, antioxidants were good. Supposedly, antioxidants reacted with free radicals, thus blocking adverse reactions. Antioxidants, heralded as a panacea for aging, instantly became the ultimate anti-aging remedy. Note: Many foods, including fruits, and vegetables contain antioxidants; and they are abundantly available as expensive dietary supplements in health food stores.

But then in the 1990s, irrefutable facts from experimental testing debunked the claims. The findings were clear. Antioxidants most certainly do not prolong life or prevent disease. Taking high dose antioxidant supplements carried a modest but consistent risk; you were more likely to die early. Bizarrely, pro-oxidants could extend the lifespan. (Free radicals in Biology and Medicine: Barry Halliwell, John Gutteridge, Clarendon Press, 1985)

In spite of these findings, fringe medicine continued to peddle the assumed benefits of antioxidants. Glossy magazines and cult books preached the false gospel of antioxidants, and the shelves of health food and drugstores remained abundantly stocked.

Studies have long shown that those on lower incomes spend a larger proportion of their incomes on food. (The Food Standards Agency Low Income Diet and Nutrition Survey (LIDNS), 2007).

It is even worse; lower income groups spend disproportionate amounts of money on heath food store supplements. That is why it hurts to see customers pay for totally worthless expensive food supplements with Food Stamp Debit cards.

Please alarm those in your circle that the antioxidants fountain of youth is a real fairytale.

By Jacob Gelt Dekker Columnist for Curaao Chronicle

View post:
Anti-aging - Curacao Chronicle

Scientists Are One Step Closer To An Anti-Aging Drug – Civilized

Posted on by

Forget the Fountain of Youth; scientists are closer than ever to creating a safe and effective anti-aging drug, its been revealed.

Through a series of experiments on mice, researchers from Harvard Medical School and the University of New South Wales School of Medicine in Australia have discovered an essential clue as to how our cells repair damaged DNA. This is important because the bodys inability to mend DNA can result in age-related deterioration, claim the scientists.

They go on to say that when humans are young, they have great amounts of the DNA-repairing protein PARP1. As we age, however, another protein called DBC1 clings to it, rendering it impossible to finish its recon work. This makes it increasingly difficult for our systems to fix broken DNA.

In their study, the researchers fed old mice a molecule called NMN. The mice metabolized it into a signalling molecule called NAD, which squeezed in between the PARP1 and DBC1 proteins and pushed them apart. The DNA-repairing protein was then able to work effectively again, just like when the mice were younger.

This restored the DNA capacity of the old mouse back to a young mouse, and also to remove the DNA damage that accumulated in the tissue, said study author David Sinclair, Ph.D.

The scientists then exposed the mice to DNA-damaging radiation. The mice that were treated with the NMN molecule didnt show the usual effects of radiation, which include changes in white blood cell counts and hemoglobin levels.

While the scientists push that the NMN treatment has only been tested in mice and that the results may be different in people, they hope to begin human trials within six months.

This is the closest we are to a safe and effective anti-aging drug thats perhaps only three to five years away from being on the market if the trials go well, Sinclair said.

The drug could one day serve as a treatment for preventing DNA damage from aging, radiation and even chemotherapy.

h/t Mens Health

See the article here:
Scientists Are One Step Closer To An Anti-Aging Drug - Civilized

FACE Forward – Hour Detroit Magazine

Posted on by

The Latest Trends in Skin, Beauty, and Wellness Offered by Michigans Rejuvenation Experts

Published: March 28, 2017

- A D V E R T I S E M E N T -

Always at the forefront of innovation in beauty and wellness, FACE and Cutler Integrative Medicine have joined to form the ultimate state-of-the-art, award-winning rejuvenation destination. The founders, Dr. Doug Cutler and Holly Cutler, have brought their naturopathic medical and esthetic backgrounds together to merge their expertise in inside-out anti-aging.

Almost two decades ago, Holly Cutler, also known as Americas Skin Saint, rebuilt her own skin, which had been disfigured by cystic acne. Since then, she has created one of the most extensive rejuvenation clinics in the U.S., offering more than 30 laser and facial machines, liquid face-lifts, vaginal rejuvenation, and body makeovers. With her innovative Skin Management Model and her one-hour transformations, Cutler has helped thousands of people who were not satisfied elsewhere. She has been a featured expert on FOX, CBS, NBC, ABC, and The Doctors Show, and has appeared on magazine covers and in several publications. Cutler has now launched her own highly anticipated and innovative skincare product line to help people all over the country who may not be able to access the services at her clinic. She is also anticipating the publication of her new book, No Filters Needed, a guide to enjoying the best skin possible for years to come.

The wellness division, headed by Dr. Doug Cutler, a licensed naturopathic physician, finds the root cause of imbalances in the body to create overall well-being from the inside out. His state-of-the-art clinic incorporates natural elements, and air and water purification systems, and is home to one of the most advanced detoxification clinics in the country. Dr. Cutler is the only doctor in Michigan who has the most advanced training in environmental medicine and genetic polymorphisms. His specialties include integrative medicine; anti-aging medicine; botanical medicine; detoxification therapies; nutrition, mental, and neurological conditions; womens disorders; childrens health; and more.

Dr. Cutler recently launched his new ClubIV, one of the only FDA/USP-compliant IV/IM

(intravenous/intramuscular) nutrient therapy clinics in Michigan. The advanced nutrient formulas are customized to increase energy, improve sleep, optimize immune function, recover cellular homeostasis, promote healing and recovery, reduce stress and anxiety, support weight loss, and much more. There is no comparison to the superior potency of nutrients delivered via IV/IM therapy. The dose bypasses the gastrointestinal system and is delivered directly into the bloodstream, so results are fast allowing you to feel better, sooner.

Most people can benefit from IV/IM therapy. At your first visit, an evaluation is conducted to determine which combination of vitamins, minerals, and other nutrients will work best for you.

The range of therapies includes anti-aging, anti-inflammatory, antioxidant, detoxification, endocrine, hydration, metabolism, recovery, and wellness. The dedicated infusion room is relaxing and peaceful; during your IV session you may experience local warmth, an increase in energy, or a deepening sense of calm and well-being.

Dr. Cutler is a member of the American Association of Naturopathic Physicians, the Michigan Association of Naturopathic Physicians, the American College for Advancement in Medicine, and the Pediatric Association of Naturopathic Physicians, and he is the board director for the Naturopathic Academy of Environmental Medicine.

As rejuvenation experts, the team of Dr. Doug Cutler and Holly Cutler can enhance your health, improve your overall quality of life, and keep you looking youthful for years to come.

The rest is here:
FACE Forward - Hour Detroit Magazine