SHOP TALK: Eldar Shafir on the effects scarcity – centraljersey.com

Memorial Day weekend followed by Princeton University reunions and graduation is a time when most Princeton residents rarely think about scarcity. Generally, the conversation under tents and in backyards is filled with groans about too much food, too much drink, too many people, too many cars, and too much stuff loaded into those cars.

On the weekend of June 10, however, several Princetonians are going to be thinking a lot about scarcity, thanks to Princeton University Professor Eldar Shafir. Dr. Shafir who is speaking at a Housing Initiatives of Princeton Garden Party benefit June 10 is internationally renowned, along with his co-author Dr. Sendhil Mullainathan from Harvard University, for the 2013 book "Scarcity: Why Having Too Little Means So Much."

As a behavioral scientist whose main area of interest is behavioral economics and decision-making, Shafir will talk about the thesis of his book the scarcity vicious cycle and relate it to the mission of HIP. Individuals with a scarcity of funds fail to make smart decisions concerning their finances for a variety of cognitive reasons, including the lack of supportive resources, thus their lives spiral downward. It turns out that the work done by HIP could be a case study for Shafirs academic work.

Since 2004, the Housing Initiatives of Princeton has been helping to break that downward spiral for dozens of people by offering a holistic menu of services to those in dire financial circumstances. It is dedicated to transitioning low-income working families and individuals who are homeless or facing imminent homelessness to permanent housing and sustained self-sufficiency.

The charitable non-profit does far more than place a temporary roof over ones head. The organization becomes a supportive resource for clients by providing individualized case management services to enhance life skills needed to attain self-sufficiency and permanent housing and ultimately to succeed independently.

Most in Princeton have a comfortable life," Shafir said. "We can afford to hire accountants, investment brokers, mortgage brokers, psychologists, attorneys to help make smart decisions about our well being. But there are those who are struggling with a scarcity of funds and do not have the support systems. The problems associated with poverty consume mental energy and capacity. Those struggling financially often make decisions that perpetuate and exacerbate poverty."

The concept of scarcity and smart decision-making applies to more than financial decisions, and thus everyone can relate to the premise of the book, regardless of his or her economic situation, noted HIP Interim Board Chair Carol Golden. The authors research and conclusions describe how scarcity creates a similar psychology for everyone struggling to manage with less than they need. Busy people fail to manage their time efficiently for the same reasons the poor and those maxed out on credit cards fail to manage their money. The dynamics of scarcity reveal why dieters find it hard to resist temptation, why students and busy executives mismanage their time.

The book is so significant, in my opinion, because it gives individuals who have no financial problems a real understanding as to why it is extremely difficult for people with great financial challenges to change their lives unless they have access to outside help, said Golden, a Princeton resident and attorney who volunteers her services as the full-time chair of the organization, officially known as Housing Initiatives of Princeton Charitable Trust.

Shafir further elaborated on his thesis in a research paper, Poverty Impedes Cognitive Function, published in the August 2013 issue of Science (written with Anandi Mani and Jiaying Zhao).

According to the papers summary, the poor often behave in less capable ways, which can further perpetuate poverty.

We hypothesize that poverty directly impedes cognitive function and present two studies that test this hypothesis," the authors wrote. "First, we experimentally induced thoughts about finances and found that this reduces cognitive performance among poor but not in well-off participants. Second, we examined the cognitive function of farmers over the planting cycle. We found that the same farmer shows diminished cognitive performance before harvest, when poor, as compared with after harvest, when rich.

"This cannot be explained by differences in time available, nutrition, or work effort. Nor can it be explained with stress: Although farmers do show more stress before harvest, that does not account for diminished cognitive performance. Instead, it appears that poverty itself reduces cognitive capacity. We suggest that this is because poverty-related concerns consume mental resources, leaving less for other tasks. These data provide a previously unexamined perspective and help explain a spectrum of behaviors among the poor.

As Princeton University Professor of Behavioral Science and Public Policy, Shafir, who has been working at the university for the past 25 years, also serves as the director (its inaugural director) of Princetons Kahneman-Treisman Center for Behavioral Science and Public Policy, and co-founder and scientific director at ideas42, a social science research and development lab.

A $10 million anonymous gift created theCenter for Behavioral Science and Public Policy at Princeton, enabling the university to strengthen its leading role in this emerging field and improve the development of effective policymaking. The donor, a Princeton University parent, was a longtime admirer of the work of Dr. Daniel Kahneman, a Nobel laureate, and a Princeton University professor of psychology and public affairs emeritus, and Dr. Anne Treisman, a Princeton University professor of psychology emerita.

The center is building on the research that earned Kahneman the Nobel Prize in economic sciences in 2002. The award-winning work integrated insights from psychological research into economics, particularly concerning decision making under uncertainty.

In the traditional view, policies are designed for people who make rational decisions based on thorough consideration of the options and on well-informed cost-benefit analyses," the university stated in a release announcing the gift in 2015. "In the approach pioneered at Princeton, policies are developed with a focus on what really drives people in decision making the idiosyncratic and sometimes surprising ways in which they view their choices, perceive the social, economic and political world around them, and decide whether or not, and how, to act. Why do some people spend too much and save too little, choose unhealthy diets that might shorten their lives?"

Princeton University President Christopher Eisgruber said:

This generous gift will allow us to deepen and expand our efforts in an extremely promising area of teaching and research. . . . Princetons faculty members are applying behavioral science techniques to topics that include law, economics, health care, household finance and dispute resolution, Princeton University President Christopher Eisgruber said. "We expect that the research conducted at the center will directly influence local, national and global public policy, identifying new approaches to address social problems and improve lives.

And HIP clients and supporters offer an abundance, not scarcity, of thanks for the academic work and research that will help HIP serve the community in the most effective manner possible.

The Housing Initiatives of Princeton will host its annual Garden Party, June 10, beginning at 4 p.m. at a private residence in Princeton. Admission costs $95 and features Shafir's talk, cocktails and light fare. To register, go towww.housinginitiativesofprinceton.org.

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SHOP TALK: Eldar Shafir on the effects scarcity - centraljersey.com

People trust science. So why don't they believe it? – KING5.com

Alia E. Dastagir , USA TODAY , TEGNA 9:48 AM. PDT June 02, 2017

Members of the Union for Concerned Scientists pose for photographs with Muppet character Beaker in front of The White House before heading to the National Mall for the March for Science rally in Washington, D.C. (Photo: Jessica Kourkounis, Getty Images)

Editor's note: This story was originally published in April. It has been updated to include the latest on the Paris climate agreement.

Thousands of scientists and their allies filled the streets of the nations capital onEarth Day for theMarch for Science, advocating for the importance of scientific truth in an era weve ominously been told doesnt value the truth any longer. Just a week later, the People's Climate March in Washington, D.C., demanded policymakers not only respect science, but that they also act on it.

And now, drawing global dismay and condemnation,President Trump has announced that the U.S. willno longer participate in the landmark Paris climate agreement.

Advocates say science is under attack. President Trumps Environmental Protection Agency chief Scott Pruitt doesnt accept evidence that shows humans are causing climate change.Education Secretary Betsy DeVos'2001 commentson wanting to advance Gods kingdom through education have educatorsworried she could undermine the teaching of evolution in public schools.Trumps budget blueprint slashes funding for the National Institutes of Health and the Department of Energy's Office of Science.

Esteemed astrophysicist Neil deGrasse Tyson, in an impassioned video on hisFacebook page, said he fears people have lost the ability to judge what's true and what's not.

"That is a recipe for the complete dismantling of our informed democracy," he says.

The scientific community is alarmed by the Trump administration, and by whatthey see as the diminishing role of objectivescience in American life. But theGeneral Social Survey, one of the oldest and most comprehensive recurring surveys of American attitudes, shows that although trust in public institutions has declined over the last half century, science is the one institution that has not suffered any erosion of public confidence. Americans who say they have a great deal of confidence in science has hovered around 40% since 1973.

Many scientists say there is no war on their profession at all.

According to the 2016 GSS data released this month, people trust scientists more than Congress (6%) and the executive branch (12%). They trust them more than the press (8%). They have more trust in scientists than in the people who run major companies (18%), more than in banks and financial institutions (14%), the Supreme Court (26%) or organized religion (20%).

So why all the headlines about the "war on science"?

Though science still holds an esteemed place in America, there isa gapbetween what scientists and some citizens think a rift that is not entirely new on issues such as climate change, nuclear power, genetically modified foods, human evolution and childhood vaccines.

Americans dont reject science as a whole. People love the weather forecast. They love their smartphones. When people reject science, its because theyre asked to believe something that conflicts with a deeply held view, whether political (myparty does not endorse that), religious (my god didnot say that) or personal (that's not how I was raised).

Manyconservatives reject the science of man-madeclimate change, just as manyliberals reject the science that shows nuclear energy can safely combat it. The views we express signal which politicalgroup we belong to. The gap between what science shows and what people believe, sociologists say, is about our identity.

The issue of climate change isnt about what you know, said Dan Kahan, a professor of psychology and law at Yale and a member of the universitysCultural CognitionProject. Its about who you are.

Polarization has exacerbated our differences, andwe know some of whats to blame:Therise of social media. A more partisan press. A dearth of universally-accepted experts. And greater access to information, which Christopher Graves, president and founder of the Ogilvy Center forBehavioralScience, said does not tug us toward the center, but rather makes us more polarized.

A human being cannot grasp something as a fact if it in any way undermines their identity, Graves said. And that is animmutable human foible. These things have always been there, but not at scale."

The GSS data show confidence in institutions overall has been in decline since the 1970s, though political scientists are quick to caution that this is animperfect benchmark.

Brendan Nyhan, a political scientist atDartmouth College, said trust in the mid-20th century was unnaturally high and polarization was unnaturally low,bolstered by unusual growth in middle class income and a reduction of inequality, which is when the "20th century version of the American dream and the trust in government to produce it was fully mythologized."

There was an usually high level of trust that came out of World War II, before the turn towards a more cynical view ofthe institutions of society especially politics and media after Vietnam and Watergate,"Nyhan said.

So how much more polarization can we expect?

Social scientists aren't sure, but they agreeTrump complicates things.

"He really is an us-versus-them figure," Kahan said. "People arent thinking about the arguments. Theyre thinkingaboutwhat side they're on."

Think about the way you search for information. If youre a new mom who believes vaccines cause autism (and a number of women in your mommy group do, too) are you searching for research that shows whether they actually do, or are you Googling vaccines cause autism to find stories to affirm your belief? (Studies show there isno link between vaccines and autism.)

The mother above is probably motivated by fear. Suchmotivated reasoning,says political scientistCharles Taberof Stony Brook University, shows that we are all fundamentally biased.

You have a basic psychological tendency to perpetuate your own beliefs, he said to really discount anything that runs against your own prior views.

It gets even more complicated.Once weve convinced ourselves of something, research suggests factsdont appeal to us.A studyco-led by Nyhanfound that trying to correct a persons misperception can have a backfire effect. When you encounter facts that dont support your idea, your belief in that idea actually grows stronger.

So what if we did a better job teaching people how science works? Doesn't help, Kahan said. Research shows peoplewith the most science intelligence are also the most partisan.

Its not knowledge but curiosity, Kahan says, that makes us more likely to accept scientific truths. Arecent studythat Kahan led found people with more scientific curiosity were more likely to be open-minded about information that challenged their existing political views.

And arguing helps, too. ScientistsHugo Mercier and Dan Sperber contend in their new book,The Enigma of Reason,that reason isn't somethingthat evolved sohumans could solve problems on their own. It developed so we could work together.

Instead of forcing someone to agree that climate change is caused by humans, Graves said, you can stop once you agree that, for example, flooding in Florida is a problem, and that you have to fix it (the biparti
sanSoutheast Florida Regional Climate Change Compactcan teach us about that).

Marcia McNutt, an American geophysicist and president of the National Academy of Sciences, said she isnt worried about a crisis of science, though she hopes more people would understand science is about the unbiased search for truth" and that benefits everyone.

Being a scientist only means that when I have an intuition about something, I test that intuition, and see if Im right, she said. A very, very smart mentor told me once, I don't trust anyone who hasn't at least changed their mind once in their career.

Science, it appears, may havemore lessons for usthan we think.

2017 USATODAY.COM

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People trust science. So why don't they believe it? - KING5.com

Why Mainstream Media Need to Be Careful About Criticizing Conservatives – Patheos (blog)

Image of newspapers (Wikipedia Commons)

Written by Dr. Gleb Tsipursky, Intentional Insights Co-Founder and President.

________________________________________________________________

Many mainstream media outlets criticized conservatives with a broad brush over the Montana Congressional special election winner Republican Greg Gianforte assaulting a reporter, Ben Jacobs. Yet, according to behavioral science research conducted by myself and others, such criticism may end up hurting the safety of journalists, instead of advancing freedom of the press and pursuit of the truth.

First, the facts of the incident itself. According to the evidence available, Gianforte grabbed Jacobs by the neck, slammed him to the ground, and punched him. The episode was witnessed and corroborated by multiple independent witnesses, including Fox News and BuzzFeed reporters. The local sheriff who earlier gave a financial contribution to Gianfortes campaign charged Gianforte with misdemeanor assault.

How did conservatives respond? The assault took place on the evening of May 24, and Fox News which had a reporter on scene quickly wrote up a fair and balanced account. The Fox News account specifically stated that at no point did any of us who witnessed this assault see Jacobs show any form of physical aggression toward Gianforte, which Fox News certainly did not have to do. In fact, the Fox News story contradicted the official statement offered by Gianfortes campaign, which accused Jacobs of starting the fight by grabbing Gianfortes wrist, a statement now widely seen as a lie. A conservative venue, TheBlaze, ran a piece critical of Gianfortes statement, and The New York Post ran a similar piece.

Many conservative politicians also responded in a worthy manner. Within 24 hours of the assault, Speaker of the House Paul Ryan stated that Theres never a call for physical altercations I think he should apologize. This length of time is quite reasonable, as Ryan needed to find out the relevant facts. Steve Daines, a Montana Senator and major supporter for Gianforte, also called on Gianforte to apologize, adding I do not condone violence in any way. Under such pressure, Gianforte rescinded his earlier deceptive official statement and instead apologized, saying I should not have treated that reporter that way, and Im sorry Ben Jacobs.

Meme saying People are most comfortable dealing with reality in terms of black or white, but reality tends to come in shades of gray (Made for Intentional Insights by Wayne Straight)

Certainly, some conservatives did not respond well. The conservative radio show host Rush Limbaugh practiced victim-blaming, implying that Gianfortes actions were not a big deal because the journalist was being insolent and disrespectful. The Daily Caller, a prominent conservative website, ran a story about some Montana voters supporting Gianfortes actions. A former Republican congressman defended Gianforte.

Such problematic responses that appeared to condone or ignore violence against reporters do not represent the majority of conservative responses. Nonetheless, The New York Times ran a story entitled A reporter was body slammed, but some conservatives want the news media to apologize. Chris Cuomo of CNN had harsh words for the Republican Party on the morning after the incident, asking You know what I hear? Silence. Where is the GOP? The Philadelphia Inquirer carried a piece entitled In Trumps America, that reporter body slam didnt come out of nowhere.

Other mainstream venues downplayed condemnation by conservatives of Gianfortes behavior and emphasized those standing by him. The Washington Post, in its editorial responding to the incident, quoted Ryans words supporting the right of people from Montanan to elect their representative, while failing to mention that he demanded an apology. In turn, The Atlantic quoted a joke made by Republican Representative Mark Sanford, while conveniently forgetting that Sanfords response also condemned the culture of hostility toward the media that contributed to Gianfortes behavior.

Meme saying Look for the actual truth, not for what just supports your beliefs (Made for Intentional Insights by Lexie Holliday)

Unfortunately, the content on these mainstream media venues fails to provide an accurate depiction of reality, which harms journalist safety. Most of the content does acknowledge in the depths of each piece that many conservatives condemned Gianfortes behavior. Yet behavioral science research on news consumption shows that 59 percent of Americans are casual readers who only read the headlines. Thus, many casual independent or conservative readers would fail to perceive the widespread condemnation by conservative leaders of Gianfortes assault.

This outcome harms the safety of journalists. Research shows that our minds interpret new information in accordance with our past beliefsa thinking error known as the confirmation bias. The confirmation bias is one of several thinking errorsknown in behavioral science scholarship as cognitive biasesthat lead to motivated reasoning, where people pre-select a certain conclusion and reach that conclusion regardless of the facts. Fortunately, we can fight the confirmation bias in such situations by evaluating the opinions of prominent influencers who have political motivations to support one side, but fail to do so or even support the other side. Such strategies have effectively changed peoples perspectives even in our current polarized environment. Unfortunately, many mainstream venues failed their readership by not conveying the data needed for them to draw accurate conclusions and thus advance press freedom.

Meme saying Lizard brain thinking is killing democracy, please think rationally (Made for Intentional Insights by Ed Coolidge)

Another problem comes from one of the strongest findings in behavioral science, which shows that human beings respond very strongly to positive reinforcement. Through the style of their coverage painting all conservatives with a broad brush, these mainstream venues fail to provide positive reinforcement to conservatives who behaved in a prosocial manner. Research suggests that optimal performance comes from a combination of internal and external motivations. External incentives according to research, are especially crucial for promoting prosocial behavior such as protecting freedom of the press.

A further issue is the equating of Trumps behavior with Gianfortes actions. Conservative venues such as Breitbart immediately took the opportunity to condemn such comparisons, and call out what the article depicted as media hypocrisy for failing to do the same when liberals used violence. As others have accurately pointed out, while Trumps actions help create a climate of hostility to the media, it is much more difficult to connect Gianfortes actions to Trumps words. Drawing such connections undermines the already-low media credibility. A much better model for reporting on this connection came from a conservative venue, The American Conservative. It ran a piece that accurately describes how the hostility to mainstream media among Republicans predated Trump, while acknowledging that Trump ramped up this hostility, and criticizing Gianforte for lacking anger management skills. Such reporting, by providing an accurate depiction that attributes only
a small part of the blame to Trumps actions, helps protect journalists.

Next time, these mainstream venues need to provide accurate reporting to avoid undercutting their credibility, to praise prosocial behavior to create incentives and positive reinforcement, and to have all readers take away accurate impressions from their headlines. You can make a difference by writing letters to the editor and making social media posts asking journalists to commit to accurate reporting and to take the Pro-Truth Pledge for the sake of protecting the safety and freedom of the press. What you can do right now is take the pledge yourself to show your own commitment to the truth.

Meme saying Why do we seek the truth? Because its the right thing to do (Made for Intentional Insights by Wayne Straight)

P.S. Want less lies in politics? Take the Pro-Truth Pledge, encourage your friends to do so, and call on your elected representatives to take it!

_______________________________________________________________

Connect with Dr. Gleb Tsipursky on Twitter, on Facebook, and on LinkedIn, and follow his RSS feed and newsletter.

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Why Mainstream Media Need to Be Careful About Criticizing Conservatives - Patheos (blog)

Pacelli’s Krusa awarded Chemistry Teacher of the Year Award – Portage County Gazette

Joyce Krusa (center) accompanied by her daughter, Alliey, and husband, Brian receives the Chemistry Teacher of the Year Award by the Central Wisconsin Section of the American Chemical Society. (Contributed photo)

Pacelli Catholic High School teacher Joyce Krusa was recently awarded the Chemistry Teacher of the Year Award by the Central Wisconsin Section of the American Chemical Society, a regional group of chemistry educators and professionals covering the central and northcentral Wisconsin region.

This year, (the) ACS-Central Wisconsin Chapter has chosen an outstanding high school chemistry teacher that (is) deserving of special recognition, said Gary Shulfer, chair of ACS-Central Wisconsin Chapter and University of Wisconsin-Stevens Point chemistry professor.

Devoting more than 15 years of her professional life to science education, Krusa possesses great leadership and has developed strong relationships with her students. As a result, more than 30 percent of her students pursue undergraduate degrees in science-related fields.

Krusa has taken on a big role in developing STEM (Science, technology, engineering and mathematics) and Project Lead the Way (PLTW) curriculum at Pacelli implementing both engineering and biomedical engineering tracks. She works to create learning opportunities for students that are rigorous and relevant.

Currently, one of her students is finishing a two-year STEM capstone internship with a local manufacturer, one of very few internships of this type for high school students in the state of Wisconsin.

I was nominated by a former student, said Krusa. The idea that a student of mine thought this much to nominate me is very humbling.

PCHS principal Larry Theiss also submitted a recommendation letter on Krusas behalf.

She constantly strives to create projects and lessons that draw they students into the learning making it fun, engaging, and interesting, said Theiss in his letter. She challenges them to expand their understanding in order to help them achieve higher levels of understanding and critical thinking.

Krusa was honored at the annual ACS-Central Wisconsin Chapter awards banquet on May 11 at Draganettis Ristorante in Eau Claire.

For my peers to recognize me for this award is one of the highlights of my teaching career, said Krusa.

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Pacelli's Krusa awarded Chemistry Teacher of the Year Award - Portage County Gazette

Bonds have changed, but chemistry among Broncos linebackers still exists – Mile High Sports

It takes a special formula to win a Super Bowl.

Balls have to bounce a certain way, difficult decisions need to be made, and sometimes it boils down to plain luck.

The Broncos discovered that their team chemistry, especially on the defensive side of the ball, was a main component in the formula that led them to their Super Bowl 50 victory in 2015.

As with any Super Bowl champion, key components of the Super Bowl team were scavenged by other teams looking for a piece of the Super Bowl pie.When linebacker Danny Trevathan was plucked by the Chicago Bears, Todd Davis was tasked with filling the voidTrevathan left in the Broncos linebacking corps.

While Davis had a fine first season as a starter, finishing with 97 tackles and a forced fumble, Brandon Marshall, who started alongside Trevathan at inside linebacker in Super Bowl 50, did admit that it was different not having Trevathan around.

Its very underrated, Marshall said of the importance of adjusting to his new teammates. When I was in there with Danny sometimes, we should have communicated when we didnt. But it was almost like I knew what he was thinking and he knew what I was thinking.

As the duo of Marshall and Davis entertheirsecond season together, both know that the chemistry is there.

I think we have it down, Marshall said of his connection with Davis. Its just a different guy; thats just what it is. Youre not going to play the same with everybody. I think what Todd and I have going on is great. We work hard, we do extra stuff. We talk ball on the sidelines. Were going to be just fine.

Just playing together, I think we have a chemistry like nobody else, Davis said following Thursdays OTA practice. We read off of each other really well. Just the last year has given us more time to grow with each other.

The Broncos linebackers can hardly be considered one of their main problems in 2016, but another year together can only make them stronger. The transition from Trevathan to Davis wasnt one that threw Marshall off of his game, but one that didnt go unnoticed either.

Im thinking that no matter who is in there, Ill be fine, Marshall said after Thursdays OTA practice. But, I think its a transition period because you have different chemistry with different people. Me and Danny [Trevathan], I knew Danny for a little bit so the type of chemistry that we had, we developed it kind of quick. Todd [Davis] is just a different player mentally than Danny, so we had to get on the same page.

The core of the Broncos defense will enter the 2017 season relatively unchanged, which will only help the bond between Marshall and Davis grow. While the bond may differ from the one that Marshall shared with Trevathan, Marshall knows that something special is brewing between the two.

I think were going to play beautifully together this year, Marshall said. Its going to be beautiful.

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Bonds have changed, but chemistry among Broncos linebackers still exists - Mile High Sports

American Society for Biochemistry and Molecular Biology Selects … – Newswise (press release)

Newswise The American Society for Biochemistry and Molecular Biology announced this week the election and appointment of seven new society leaders. They begin their terms July 1.

President-elect

Gerald Hart, Johns Hopkins School of Medicine, who studies nutrient regulation of signaling and transcription.

Council

Takita Sumter, Winthrop University, who studies high-mobility group A proteins in cancer signaling.

JoAnn Trejo, University of California, San Diego, who studies G proteincoupled-receptor signal transduction.

Publications committee

Brian Crane, Cornell University, who studies molecular mechanisms of signal transduction.

Ruth Welti, Kansas State University, who studieslipid metabolism and plant response to environmental stress.

Nominating committee

Anthony Kossiakoff, University of Chicago, who studiesligand-induced receptor activation, antibody engineering and drug delivery.

Iqbal Hamza, University of Maryland, who studies heme trafficking in iron homeostasis.

Note to reporters and PIOs: Print-quality images are available upon request. Email Angela Hopp at ahopp@asbmb.org.

###

About the American Society for Biochemistry and Molecular Biology

The ASBMB is a nonprofit scientific and educational organization with more than 12,000 members worldwide. Most members teach and conduct research at colleges and universities. Others conduct research in various government laboratories, at nonprofit research institutions and in industry. The Societys student members attend undergraduate or graduate institutions. For more information about ASBMB, visit http://www.asbmb.org.

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American Society for Biochemistry and Molecular Biology Selects ... - Newswise (press release)

When will ‘Grey’s Anatomy’ season 14 premiere? – Blasting News

"Grey's Anatomy" season 13 may have only just finished two weeks ago, but fans are already looking for details about season 14.Just when will the show premiere on #ABC? Unfortunately, only CBS has released its fall 2017 schedule dates right now, but it shouldn't be too long before ABC follows suit. We can work out a rough date to pencil in your diary for now, and share all we know about "#Grey's Anatomy" season 14 so far.

Based on last season, a rough start date for season 14 will be September 28. We know that the show is definitely returning to its usual Thursday night 8 p.m. slot. Why change something that clearly isn't broken? It will also be the first of three Shonda Rhimes shows, with the final season of "Scandal" and then "How to Get Away with Murder" following on.

There is a lot of hype around one of Rhimes' newest planned shows. She plans to create a "Grey's" spinoff focused on firefighters, nicknamed "Seattle Fire." Very little is known about that so far.

One of the biggest storylines to focus on for "Grey's Anatomy" season 14 will be Megan Hunt's arrival. Previously believed dead, it turned out that Owen's sister and Riggs' ex-fiancee was actually held captive. She has been found and is now in Seattle for recovery.

This changes everything for our two doctors. Owen and Riggs are already suffering from the guilt of believing that she was dead. However, Owen still has issues with Amelia to discuss and those discussions can't happen now. Riggs had also started dating Meredith, but Meredith made it clear to put Megan first.

Throughout season 13, Maggie was in a love triangle without even knowing.

She liked Riggs, but Riggs and Meredith had already started hooking up. She'd only just gotten over the feeling of betrayal before finding out that Jackson is interested in her. This puts her in an awkward position again, as April clearly isn't happy with this development.

Fans aren't happy with the reveal that Jackson likes Maggie. For many fans, it came out of the blue and it means Jackson and April won't get back together, despite hooking up in Montana. It is possible this storyline will change direction based on the fan response.

"Grey's Anatomy" season 14 will likely return on September 28 or close to that date. It will definitely be back on Thursdays on ABC for the fall 2017 schedule. What do you think will happen in season 14?

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When will 'Grey's Anatomy' season 14 premiere? - Blasting News

The American Academy of Anti-Aging Medicine (A4M) and Metabolic Medical Institute (MMI) have been – PR Newswire UK (press release)

The Fellowship in Metabolic and Nutritional Medicine is an interactive educational experience that combines modular training with hands-on clinical practice and web broadcasts, while instilling practitioners with the necessary knowledge and skills to effectively practice regenerative and functional medicine. The Fellowship is comprised of the latest findings and research in the areas of endocrinology, cardiology, neurology, nutrition, and a variety of other health fields, and is available to all physicians and healthcare practitioners with active medical licenses.

As the world's largest non-profit society of physicians and scientists committed to research that helps optimize the human aging process, along with the advancement of techniques and technologies that detect, prevent, and treat aging-related diseases, The American Academy of Anti-Aging Medicine has collaborated with MMI to provide the RCGP with high quality information and guidance. The A4M is dedicated to the education of all healthcare professionals, and is proud to be in its 25th year of providing first-class continuing education conferences on anti-aging, regenerative, and functional medicine.

A4M & MMI work collectively to ensure that general practitioners are fully equipped with the knowledge and clinical skills in order to provide the best standards of care for patients.

Tolearn more,registerfor events,enrollin training programs, orexhibitat an A4M Conference, please contact the office of The American Academy of Anti-Aging Medicine at:

Toll-Free - US Only:(888) 997-0112International:(561) 997-0112Email: internationalevents@a4m.com

SOURCE American Academy of Anti-Aging Medicine

http://www.a4m.com

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The American Academy of Anti-Aging Medicine (A4M) and Metabolic Medical Institute (MMI) have been - PR Newswire UK (press release)

People trust science. So why don't they believe it? – WGRZ-TV

Alia E. Dastagir , USA TODAY , TEGNA 12:48 PM. EDT June 02, 2017

Members of the Union for Concerned Scientists pose for photographs with Muppet character Beaker in front of The White House before heading to the National Mall for the March for Science rally in Washington, D.C. (Photo: Jessica Kourkounis, Getty Images)

Editor's note: This story was originally published in April. It has been updated to include the latest on the Paris climate agreement.

Thousands of scientists and their allies filled the streets of the nations capital onEarth Day for theMarch for Science, advocating for the importance of scientific truth in an era weve ominously been told doesnt value the truth any longer. Just a week later, the People's Climate March in Washington, D.C., demanded policymakers not only respect science, but that they also act on it.

And now, drawing global dismay and condemnation,President Trump has announced that the U.S. willno longer participate in the landmark Paris climate agreement.

Advocates say science is under attack. President Trumps Environmental Protection Agency chief Scott Pruitt doesnt accept evidence that shows humans are causing climate change.Education Secretary Betsy DeVos'2001 commentson wanting to advance Gods kingdom through education have educatorsworried she could undermine the teaching of evolution in public schools.Trumps budget blueprint slashes funding for the National Institutes of Health and the Department of Energy's Office of Science.

Esteemed astrophysicist Neil deGrasse Tyson, in an impassioned video on hisFacebook page, said he fears people have lost the ability to judge what's true and what's not.

"That is a recipe for the complete dismantling of our informed democracy," he says.

The scientific community is alarmed by the Trump administration, and by whatthey see as the diminishing role of objectivescience in American life. But theGeneral Social Survey, one of the oldest and most comprehensive recurring surveys of American attitudes, shows that although trust in public institutions has declined over the last half century, science is the one institution that has not suffered any erosion of public confidence. Americans who say they have a great deal of confidence in science has hovered around 40% since 1973.

Many scientists say there is no war on their profession at all.

According to the 2016 GSS data released this month, people trust scientists more than Congress (6%) and the executive branch (12%). They trust them more than the press (8%). They have more trust in scientists than in the people who run major companies (18%), more than in banks and financial institutions (14%), the Supreme Court (26%) or organized religion (20%).

So why all the headlines about the "war on science"?

Though science still holds an esteemed place in America, there isa gapbetween what scientists and some citizens think a rift that is not entirely new on issues such as climate change, nuclear power, genetically modified foods, human evolution and childhood vaccines.

Americans dont reject science as a whole. People love the weather forecast. They love their smartphones. When people reject science, its because theyre asked to believe something that conflicts with a deeply held view, whether political (myparty does not endorse that), religious (my god didnot say that) or personal (that's not how I was raised).

Manyconservatives reject the science of man-madeclimate change, just as manyliberals reject the science that shows nuclear energy can safely combat it. The views we express signal which politicalgroup we belong to. The gap between what science shows and what people believe, sociologists say, is about our identity.

The issue of climate change isnt about what you know, said Dan Kahan, a professor of psychology and law at Yale and a member of the universitysCultural CognitionProject. Its about who you are.

Polarization has exacerbated our differences, andwe know some of whats to blame:Therise of social media. A more partisan press. A dearth of universally-accepted experts. And greater access to information, which Christopher Graves, president and founder of the Ogilvy Center forBehavioralScience, said does not tug us toward the center, but rather makes us more polarized.

A human being cannot grasp something as a fact if it in any way undermines their identity, Graves said. And that is animmutable human foible. These things have always been there, but not at scale."

The GSS data show confidence in institutions overall has been in decline since the 1970s, though political scientists are quick to caution that this is animperfect benchmark.

Brendan Nyhan, a political scientist atDartmouth College, said trust in the mid-20th century was unnaturally high and polarization was unnaturally low,bolstered by unusual growth in middle class income and a reduction of inequality, which is when the "20th century version of the American dream and the trust in government to produce it was fully mythologized."

There was an usually high level of trust that came out of World War II, before the turn towards a more cynical view ofthe institutions of society especially politics and media after Vietnam and Watergate,"Nyhan said.

So how much more polarization can we expect?

Social scientists aren't sure, but they agreeTrump complicates things.

"He really is an us-versus-them figure," Kahan said. "People arent thinking about the arguments. Theyre thinkingaboutwhat side they're on."

Think about the way you search for information. If youre a new mom who believes vaccines cause autism (and a number of women in your mommy group do, too) are you searching for research that shows whether they actually do, or are you Googling vaccines cause autism to find stories to affirm your belief? (Studies show there isno link between vaccines and autism.)

The mother above is probably motivated by fear. Suchmotivated reasoning,says political scientistCharles Taberof Stony Brook University, shows that we are all fundamentally biased.

You have a basic psychological tendency to perpetuate your own beliefs, he said to really discount anything that runs against your own prior views.

It gets even more complicated.Once weve convinced ourselves of something, research suggests factsdont appeal to us.A studyco-led by Nyhanfound that trying to correct a persons misperception can have a backfire effect. When you encounter facts that dont support your idea, your belief in that idea actually grows stronger.

So what if we did a better job teaching people how science works? Doesn't help, Kahan said. Research shows peoplewith the most science intelligence are also the most partisan.

Its not knowledge but curiosity, Kahan says, that makes us more likely to accept scientific truths. Arecent studythat Kahan led found people with more scientific curiosity were more likely to be open-minded about information that challenged their existing political views.

And arguing helps, too. ScientistsHugo Mercier and Dan Sperber contend in their new book,The Enigma of Reason,that reason isn't somethingthat evolved sohumans could solve problems on their own. It developed so we could work together.

Instead of forcing someone to agree that climate change is caused by humans, Graves said, you can stop once you agree that, for example, flooding in Florida is a problem, and that you have to fix it (the bipart
isanSoutheast Florida Regional Climate Change Compactcan teach us about that).

Marcia McNutt, an American geophysicist and president of the National Academy of Sciences, said she isnt worried about a crisis of science, though she hopes more people would understand science is about the unbiased search for truth" and that benefits everyone.

Being a scientist only means that when I have an intuition about something, I test that intuition, and see if Im right, she said. A very, very smart mentor told me once, I don't trust anyone who hasn't at least changed their mind once in their career.

Science, it appears, may havemore lessons for usthan we think.

2017 USATODAY.COM

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People trust science. So why don't they believe it? - WGRZ-TV

UB program for underrepresented minority students in biomedical PhD programs wins coveted renewal – UB News Center

BUFFALO, N.Y. The University at Buffalos ongoing efforts to recruit underrepresented students in science, technology, engineering and mathematics (STEM) to its PhD programs has received a major boost from the National Institutes of Health, which renewed a $2.3 million, 5-year grant to help fully fund scholarships.

The grant will pay for the first two years of graduate school in the biomedical and behavioral sciences for four students a year. Over the past five years, the program is credited with bringing 20 underrepresented students to UB. And more importantly, it is part of a pipeline of catalysts that is helping the university attract underrepresented students to prepare the next generation of scientists and professors.

These students are highly recruited by other universities, said Margarita Dubocovich, PhD, SUNY Distinguished Professor in the Department of Pharmacology and Toxicology in the Jacobs School of Medicine and Biomedical Sciences and senior associate dean for diversity and inclusion.

The grant is part of the Initiative for Maximizing Student Development (IMSD), a student development program for research-intensive institutions funded by NIHs National Institute of General Medical Sciences. The prestigious grant was awarded to only 21 PhD training programs.

Numerous departments involved

Students admitted into UB's IMSD can enroll in any of the following UB programs or departments: biological sciences; biomedical engineering; chemistry; psychology; pharmacology and toxicology; pharmaceutical sciences; the PhD program in biomedical sciences; and the graduate division at Roswell Park Cancer Institute.

Dubocovich said the grant combined with UBs Institute for the Strategic Enhancement of Educational Diversity (iSEED) and its Collaborative Learning and Integrated Mentoring in the Biosciences (CLIMB) program has helped UB recruit 37 underrepresented students in STEM and related fields to its graduate programs over the past five years. And the deans of seven schools at UB have pledged to fund one underrepresented student a year.

These PhD graduate students are a cohort that helped win the grant renewal, she said. Helping diversify the ranks of the graduate programs has ramifications across the university.

When you recruit faculty, and they know we are actively recruiting underrepresented students, they are more apt to come here, Dubocovich said. They want to have a more diverse class.

National recruitment

Renewal of the grant was a significant win for the efforts of Dubocovich and her co-leader in the recruitment efforts, Rajendram V. Rajnarayanan, PhD, assistant professor of pharmacology and toxicology.

We must be doing something right, said Rajnarayanan, who likens the IMSD grant to a biological catalyst that helps keep students moving toward successful graduation and leadership roles in their scientific communities.

Dubocovich and Rajnarayanan attend conferences and speak to college groups to help recruit students to the university. In addition, they have established programs to bring promising undergraduate students to campus in the summer for a research training program.

We go and visit schools and speak passionately about research, so the students see it and want to be involved, said Rajnarayanan. Thats how it works.

We recruit nationally, Dubocovich said. We bring them here so they can learn about UB and see whether they want to come here for graduate school.

Owing to the IMSD program, the number of admissions offers made to students from diverse backgrounds has more than doubled, she said. The total number of underrepresented PhD students with thesis mentors in the Department of Pharmacology and Toxicology increased from 18 percent (2 out of 11) in 2011 to 58 percent (11 out of 19) in fall 2016.

Similarly, first year student enrollment in the PhD program in biomedical sciences has increased from 8 percent in 2008-2011 to 24 percent in 2012-2015. Together, these datahighlight the broader impact of the IMSD program in student enrollment at UB.

First two years are key

Rajnarayanan said the university has built a pipeline for the students, starting with the summer program and continuing through graduate school, that includes mentoring and research opportunities. Under the IMSD grant, PhD students have individual mentoring during the first two years of the program, and gather as a group regularly.

Statistically, if a student makes it through the first two years, they stay for the entire program, he said.

All students seeking an IMSD grant must first be accepted into a PhD program, and then the individual school that nominated them for the grant. Each year, up to 18 students are nominated and out of those, four students are accepted.

Continued here:
UB program for underrepresented minority students in biomedical PhD programs wins coveted renewal - UB News Center

Why Mainstream Media Need to Be Careful About Criticizing Conservatives – HuffPost

Written by Dr. Gleb Tsipursky, Intentional Insights Co-Founder and President.

________________________________________________________________

Many mainstream media outlets criticized conservatives with a broad brush over the Montana Congressional special election winner Republican Greg Gianforte assaulting a reporter, Ben Jacobs. Yet, according to behavioral science research conducted by myself and others, such criticism may end up hurting the safety of journalists, instead of advancing freedom of the press and pursuit of the truth.

First, the facts of the incident itself. According to the evidence available, Gianforte grabbed Jacobs by the neck, slammed him to the ground, and punched him. The episode was witnessed and corroborated by multiple independent witnesses, including Fox News and BuzzFeed reporters. The local sheriff - who earlier gave a financial contribution to Gianfortes campaign - charged Gianforte with misdemeanor assault.

How did conservatives respond? The assault took place on the evening of May 24, and Fox News - which had a reporter on scene - quickly wrote up a fair and balanced account. The Fox News account specifically stated that at no point did any of us who witnessed this assault see Jacobs show any form of physical aggression toward Gianforte, which Fox News certainly did not have to do. In fact, the Fox News story contradicted the official statement offered by Gianfortes campaign, which accused Jacobs of starting the fight by grabbing Gianfortes wrist, a statement now widely seen as a lie. A conservative venue, TheBlaze, ran a piece critical of Gianfortes statement, and The New York Post ran a similar piece.

Many conservative politicians also responded in a worthy manner. Within 24 hours of the assault, Speaker of the House Paul Ryan stated that There's never a call for physical altercations... I think he should apologize." This length of time is quite reasonable, as Ryan needed to find out the relevant facts. Steve Daines, a Montana Senator and major supporter for Gianforte, also called on Gianforte to apologize, adding "I do not condone violence in any way. Under such pressure, Gianforte rescinded his earlier deceptive official statement and instead apologized, saying I should not have treated that reporter that way, and Im sorry Ben Jacobs.

Certainly, some conservatives did not respond well. The conservative radio show host Rush Limbaugh practiced victim-blaming, implying that Gianfortes actions were not a big deal because the journalist was being insolent and disrespectful. The Daily Caller, a prominent conservative website, ran a story about some Montana voters supporting Gianfortes actions. A former Republican congressman defended Gianforte.

Such problematic responses that appeared to condone or ignore violence against reporters do not represent the majority of conservative responses. Nonetheless, The New York Times ran a story entitled A reporter was body slammed, but some conservatives want the news media to apologize. Chris Cuomo of CNN had harsh words for the Republican Party on the morning after the incident, asking You know what I hear? Silence. Where is the GOP? The Philadelphia Inquirer carried a piece entitled In Trump's America, that reporter body slam didn't come out of nowhere.

Other mainstream venues downplayed condemnation by conservatives of Gianfortes behavior and emphasized those standing by him. The Washington Post, in its editorial responding to the incident, quoted Ryans words supporting the right of people from Montanan to elect their representative, while failing to mention that he demanded an apology. In turn, The Atlantic quoted a joke made by Republican Representative Mark Sanford, while conveniently forgetting that Sanfords response also condemned the culture of hostility toward the media that contributed to Gianfortes behavior .

Unfortunately, the content on these mainstream media venues fails to provide an accurate depiction of reality, which harms journalist safety. Most of the content does acknowledge - in the depths of each piece - that many conservatives condemned Gianfortes behavior. Yet behavioral science research on news consumption shows that 59 percent of Americans are casual readers who only read the headlines. Thus, many casual independent or conservative readers would fail to perceive the widespread condemnation by conservative leaders of Gianfortes assault.

This outcome harms the safety of journalists. Research shows that our minds interpret new information in accordance with our past beliefsa thinking error known as the confirmation bias. The confirmation bias is one of several thinking errorsknown in behavioral science scholarship as cognitive biasesthat lead to motivated reasoning, where people pre-select a certain conclusion and reach that conclusion regardless of the facts. Fortunately, we can fight the confirmation bias in such situations by evaluating the opinions of prominent influencers who have political motivations to support one side, but fail to do so or even support the other side. Such strategies have effectively changed peoples perspectives even in our current polarized environment. Unfortunately, many mainstream venues failed their readership by not conveying the data needed for them to draw accurate conclusions and thus advance press freedom.

Another problem comes from one of the strongest findings in behavioral science, which shows that human beings respond very strongly to positive reinforcement. Through the style of their coverage painting all conservatives with a broad brush, these mainstream venues fail to provide positive reinforcement to conservatives who behaved in a prosocial manner. Research suggests that optimal performance comes from a combination of internal and external motivations. External incentives according to research, are especially crucial for promoting prosocial behavior such as protecting freedom of the press.

A further issue is the equating of Trumps behavior with Gianfortes actions. Conservative venues such as Breitbart immediately took the opportunity to condemn such comparisons, and call out what the article depicted as media hypocrisy for failing to do the same when liberals used violence. As others have accurately pointed out, while Trumps actions help create a climate of hostility to the media, it is much more difficult to connect Gianfortes actions to Trumps words. Drawing such connections undermines the already-low media credibility. A much better model for reporting on this connection came from a conservative venue, The American Conservative. It ran a piece that accurately describes how the hostility to mainstream media among Republicans predated Trump, while acknowledging that Trump ramped up this hostility, and criticizing Gianforte for lacking anger management skills. Such reporting, by providing an accurate depiction that attributes only a small part of the blame to Trumps actions, helps protect journalists.

Next time, these mainstream venues need to provide accurate reporting to avoid undercutting their credibility, to praise prosocial behavior to create incentives and positive reinforcement, and to have all readers take away accurate impressions from their headlines. You can make a difference by writing letters to the editor and making social media posts asking journalists to commit to accurate
reporting and to take the Pro-Truth Pledge for the sake of protecting the safety and freedom of the press. What you can do right now is take the pledge yourself to show your own commitment to the truth.

P.S. Want less lies in politics? Take the Pro-Truth Pledge, encourage your friends to do so, and call on your elected representatives to take it!

_______________________________________________________________

Connect with Dr. Gleb Tsipursky on Twitter, on Facebook, and on LinkedIn, and follow his RSS feed and newsletter.

Start your workday the right way with the news that matters most.

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Why Mainstream Media Need to Be Careful About Criticizing Conservatives - HuffPost

IBM's Watson – Best Doctor In The World? – Anti Aging News

The Watson supercomputer, created by technology company IBM, uses the power of artificial intelligence (AI) in ways that benefit mankind. In 2011, the world was introduced to the potential of AI when Watson won the title of world champion on the popular game show Jeopardy! In 2011.

Since then, Watsons developers have focused on customizing the AI for medical use. Programmers have integrated thousands of patient records, scores of medical texts, and all the content in the PubMed and Medline databases into Watsons working memory. In all, the AI has consumed 2 million pages of text that represent over 600,000 pieces of medical evidence, 25,000 training cases, and 14,700 hours of clinical training.

The Benefits of Using AI in Medical Diagnoses

AI programs, like Watson, are gaining importance in information-heavy fields, like medicine. The supercomputer is able to store more information than a human brain and can access the information more quickly. In addition, a computer-generated diagnosis is based on evidence and established fact, while human doctors may be swayed by cognitive biases or confidence issues.

The Watson AI uses an interface that allows users to speak to it in a natural way. The machine is able to gather and analyze information from patients and compare it to stored information. Based on this inquiry, the AI can then make an accurate diagnosis.

More than just comparing bits of information, the Watson supercomputer is able to form hypotheses independently. In a process that is similar to the way humans learn, the machine can then test and evaluate its own hypotheses, disregarding what doesnt work and adjusting for error.

In 2011, McAfee wrote about the advantages of using AI for medical purposes. AI diagnoses are based on the complete published body of medical knowledge, making it the most up-to-date medical resource. Diagnostic programs are also accurate, consistent, cost very little to operate, and can be used anywhere in the world.

AI: The Future in Medical Care

When using AI for diagnostics, a physician describes symptoms and other contributing factors to the program. The computer then mines patient history and its own databases, and along with test results and other pieces of medically relevant data, creates a hypothesis. The hypothesis is tested against its information on treatments, hospital records, and published studies and research. Once satisfied that the hypothesis is valid, Watson can then give a customized treatment plan for the patient.

While Watson has incredible capacity, only a few companies are taking advantage of it. MD Anderson Cancer Center uses AI to develop treatment plans for leukemia patients. The medical company WellPoint uses Watson-based software to allow patients to evaluate their doctors treatment plans.

Currently, the Watson AI is not able to fully use all of the information it has access to. Developers are working with the program to help it develop the mental agility and versatility of thought that makes human doctors so effective.

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IBM's Watson - Best Doctor In The World? - Anti Aging News

The American Academy of Anti-Aging Medicine (A4M) and Metabolic Medical Institute (MMI) have been – PR Newswire UK (press release)

The Fellowship in Metabolic and Nutritional Medicine is an interactive educational experience that combines modular training with hands-on clinical practice and web broadcasts, while instilling practitioners with the necessary knowledge and skills to effectively practice regenerative and functional medicine. The Fellowship is comprised of the latest findings and research in the areas of endocrinology, cardiology, neurology, nutrition, and a variety of other health fields, and is available to all physicians and healthcare practitioners with active medical licenses.

As the world's largest non-profit society of physicians and scientists committed to research that helps optimize the human aging process, along with the advancement of techniques and technologies that detect, prevent, and treat aging-related diseases, The American Academy of Anti-Aging Medicine has collaborated with MMI to provide the RCGP with high quality information and guidance. The A4M is dedicated to the education of all healthcare professionals, and is proud to be in its 25th year of providing first-class continuing education conferences on anti-aging, regenerative, and functional medicine.

A4M & MMI work collectively to ensure that general practitioners are fully equipped with the knowledge and clinical skills in order to provide the best standards of care for patients.

Tolearn more,registerfor events,enrollin training programs, orexhibitat an A4M Conference, please contact the office of The American Academy of Anti-Aging Medicine at:

Toll-Free - US Only:(888) 997-0112International:(561) 997-0112Email: internationalevents@a4m.com

SOURCE American Academy of Anti-Aging Medicine

http://www.a4m.com

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The American Academy of Anti-Aging Medicine (A4M) and Metabolic Medical Institute (MMI) have been - PR Newswire UK (press release)

Hillsboro Native Earns Honors At Vanderbilt – thejournal-news.net

Hillsboro native Dr. Nancy J. Cox was honored this spring as the first recipient of the Richard M. Caprioli Research Award. Dr. Cox is currently the director of the Vanderbilt Genetics Institute in Nashville, TN.

The daughter of the late Gene and Helen Cox, she is a 1974 graduate of Hillsboro High School and was selected as the second Hillsboro Education Foundation Distinguished Alumni Award recipient in 2002.

Dr. Cox earned her bachelor of science degree in biology from the University of Notre Dame in 1978 and her doctorate in human genetics from Yale University in 1982.

She completed a postdoctoral fellowship in genetic epidemiology at Washington University and was a research associate in human genetics at the University of Pennsylvania.

In 1987, she was hired at the University of Chicago. She was appointed full professor in the departments of medicine and human genetics in 2004 and chief of the section of genetic medicine the following year.

In 2012, she was named a University of Chicago Pritzker Scholar. In 2015, Dr. Cox was hired at Vanderbilt University School of Medicine as the Mary Phillips Edmonds Gray Professor of Genetics, founding director of the Vanderbilt Genetics Institute and director of the Division of Genetic Medicine in the Department of Medicine. She is a fellow of the American Association for the Advancement of Science

Throughout her career as a quantitative geneticist, Dr. Cox has sought to identify and characterize the genetic component to common human diseases and clinical phenotypes like pharmacogenomics traits (how genes affect drug response).

Her work has advanced methods for analyzing genetic and genomic data from a wide range of complex traits and diseases, including breast cancer, diabetes, autism, schizophrenia, bipolar disorder, Tourette syndrome, obsessive-compulsive disorder, stuttering and speech and language impairment.

Through the national Genotype Tissue Expression (GTEx) project, Dr. Cox also contributed to the development of genome predictors of the expression of genes, and she also has investigated the genetics of cardiometabolic phenotypes such as lipids, diabetes and cardiovascular disease.

With colleagues at the University of Michigan, Dr. Cox is generating content for the Accelerating Medicine Partnership between the National Institutes of Health (NIH), U.S. Food and Drug Administration, biopharmaceutical companies and non-profit organizations. The goal of the partnership is to identify and validate promising biological targets, increase the number of new diagnostics and therapies for patients, and reduce the cost and time it takes to develop them.

Dr. Cox is co-principal investigator of an analytic center within the Centers for Common Disease Genomics, another NIH initiative that is using genome sequencing to explore the genomic contributions to common diseases such as heart disease, diabetes, stroke and autism. A major resource for the Cox lab is Vanderbilts massive biobank, BioVU, which contains DNA samples from more than 230,000 individuals that are linked to de-identified electronic health records.

Dr. Cox is the author or co-author of more than 300 peer-reviewed scientific articles. She is former editor-in-chief of the journal Genetic Epidemiology, and is the current president of the American Society of Human Genetics.

For developing new methods that have aided researchers worldwide in identifying and characterizing of the genetic and genomic underpinnings of diseases and complex traits, Dr. Cox is the first recipient of the inaugural Richard M. Caprioli Research Award.

Dr. Cox and her husband, Dr. Paul Epstein live in Nashville, TN, and have two grown daughters, Bonnie Epstein and Carrie Epstein.

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Hillsboro Native Earns Honors At Vanderbilt - thejournal-news.net

One gene closer to regenerative therapy for muscular disorders – Medical Xpress

June 1, 2017 This microscopic image of fibroblast cells shows the induction of cell fusion by a newly described gene and its protein, called myomerger. Multi-nucleus cells expressing genes needed to form skeletal muscle can be seen in flower-like clumps forming as cells fuse together. Reporting results in Nature Communications, the researchers seek ways to develop regenerative therapies for muscle disorders by getting stem cells to fuse and form functioning skeletal muscle tissues. Credit: Cincinnati Children's

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues. A study published June 1 by Nature Communications reports scientists identify a new gene essential to this process, shedding new light on possible new therapeutic strategies.

Led by researchers at the Cincinnati Children's Hospital Medical Center Heart Institute, the study demonstrates the gene Gm7325 and its protein - which the scientists named "myomerger" - prompt muscle stem cells to fuse and develop skeletal muscles the body needs to move and survive. They also show that myomerger works with another gene, Tmem8c, and its associated protein "myomaker" to fuse cells that normally would not.

In laboratory tests on embryonic mice engineered to not express myomerger in skeletal muscle, the animals did not develop enough muscle fiber to live.

"These findings stimulate new avenues for cell therapy approaches for regenerative medicine," said Douglas Millay, PhD, study senior investigator and a scientist in the Division of Molecular Cardiovascular Biology at Cincinnati Children's. "This includes the potential for cells expressing myomaker and myomerger to be loaded with therapeutic material and then fused to diseased tissue. An example would be muscular dystrophy, which is a devastating genetic muscle disease. The fusion technology possibly could be harnessed to provide muscle cells with a normal copy of the missing gene."

Bio-Pioneering in Reverse

One of the molecular mysteries hindering development of regenerative therapy for muscles is uncovering the precise genetic and molecular processes that cause skeletal muscle stem cells (called myoblasts) to fuse and form the striated muscle fibers that allow movement. Millay and his colleagues are identifying, deconstructing and analyzing these processes to search for new therapeutic clues.

Genetic degenerative disorders of the muscle number in the dozens, but are rare in the overall population, according to the National Institutes of Health. The major categories of these devastating wasting diseases include: muscular dystrophy, congenital myopathy and metabolic myopathy. Muscular dystrophies are a group of more than 30 genetic diseases characterized by progressive weakness and degeneration of the skeletal muscles that control movement. The most common form is Duchenne MD.

Molecular Sleuthing

A previous study authored by Millay in 2014 identified myomaker and its gene through bioinformatic analysis. Myomaker is also required for myoblast stem cells to fuse. However, it was clear from that work that myomaker did not work alone and needed a partner to drive the fusion process. The current study indicates that myomerger is the missing link for fusion, and that both genes are absolutely required for fusion to occur, according to the researchers.

To find additional genes that regulate fusion, Millay's team screened for those activated by expression of a protein called MyoD, which is the primary initiator of the all the genes that make muscle. The team focused on the top 100 genes induced by MyoD (including GM7325/myomerger) and designed a screen to test the factors that could function within and across cell membranes. They also looked for genes not previously studied for having a role in fusing muscle stem cells. These analyses eventually pointed to a previously uncharacterized gene listed in the database - Gm7325.

Researchers then tested cell cultures and mouse models by using a gene editing process called CRISPR-Cas9 to demonstrate how the presence or absence of myomaker and myomerger - both individually and in unison - affect cell fusion and muscle formation. These tests indicate that myomerger-deficient muscle cells called myocytes differentiate and form the contractile unit of muscle (sarcomeres), but they do not join together to form fully functioning muscle tissue.

Looking Ahead

The researchers are building on their current findings, which they say establishes a system for reconstituting cell fusion in mammalian cells, a feat not yet achieved by biomedical science.

For example, beyond the cell fusion effects of myomaker and myomerger, it isn't known how myomaker or myomerger induce cell membrane fusion. Knowing these details would be crucial to developing potential therapeutic strategies in the future, according to Millay. This study identifies myomerger as a fundmentally required protein for muscle development using cell culture and laboratory mouse models.

The authors emphasize that extensive additional research will be required to determine if these results can be translated to a clinical setting.

Explore further: Researchers turn stem cells into somites, precursors to skeletal muscle, cartilage and bone

More information: Nature Communications (2017). DOI: 10.1038/NCOMMS15665

Adding just the right mixture of signaling moleculesproteins involved in developmentto human stem cells can coax them to resemble somites, which are groups of cells that give rise to skeletal muscles, bones, and cartilage ...

A team led by Jean-Franois Ct, researcher at the IRCM, identified a ''conductor'' in the development of muscle tissue. The discovery, published online yesterday by the scientific journal Proceedings of the National ...

Athletes, the elderly and those with degenerative muscle disease would all benefit from accelerated muscle repair. When skeletal muscles, those connected to the bone, are injured, muscle stem cells wake up from a dormant ...

Johns Hopkins researchers report they have inadvertently found a way to make human muscle cells bearing genetic mutations from people with Duchenne muscular dystrophy (DMD).

Duchenne muscular dystrophy is a chronic disease causing severe muscle degeneration that is ultimately fatal. As the disease progresses, muscle precursor cells lose the ability to create new musclar tissue, leading to faster ...

Researchers at Sanford Burnham Prebys Medical Research Institute (SBP) have conclusively identified the protein complex that controls the genes needed to repair skeletal muscle. The discovery clears up deep-rooted conflicting ...

A University of California, Berkeley, study of mice reveals, for the first time, how puberty hormones might impede some aspects of flexible youthful learning.

The bacteria in a child's gut appears to be influenced as early as its first year by ethnicity and breastfeeding, according to a new study from McMaster University.

The human body runs according to a roughly 24-hour cycle, controlled by a "master" clock in the brain and peripheral clocks in other parts of the body that are synchronized according to external cues, including light. Now, ...

A detour on the road to regenerative medicine for people with muscular disorders is figuring out how to coax muscle stem cells to fuse together and form functioning skeletal muscle tissues. A study published June 1 by Nature ...

Cholesterol, a naturally occurring compound at the lung surface, has been shown to have a clear effect on the properties of this nanoscale film that covers the inside of our lungs. Cholesterol levels in this system may affect ...

Researchers from Monash University have developed a new drug delivery strategy able to block pain within the nerve cells, in what could be a major development of an immediate and long lasting treatment for pain.

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One gene closer to regenerative therapy for muscular disorders - Medical Xpress

Here’s Why Editas Medicine Fell as Much as 15.7% Today – Motley Fool

What happened

Shares of gene editing pioneer Editas Medicine (NASDAQ:EDIT) dropped nearly 16% today after a new study published in Nature Methods drew attention to unintended effects of using the highly touted genetic engineering tool known as CRISPR. Shares of genome-editing peers CRISPR Therapeutics (NASDAQ:CRSP) and Intellia Therapeutics (NASDAQ:NTLA) were down as much as 6.9% and 14.9%, respectively, on the news.

The study, conducted by a team from Columbia University Medical Center, provided data showing that the technology can "introduce hundreds of unintended mutations into the genome," according to Genetic Engineering & Biotechnology News. That contradicts one of the better-known characteristics of CRISPR: precision.

Simply put, it's not sitting well with investors, who are (in knee-jerk fashion) adjusting the value placed on early-stage platforms, especially Editas Medicine, which will be the first of the group to enter clinical trials. As of 3:31 p.m. EDT, the stock had settled to a 11.3% loss.

Image source: Getty Images.

The study is among the first to quantify the specificity of CRISPR tools, which work by delivering gene editing enzymes to specific parts of the genome through the use of synthetic guide RNAs. Or that's how they're supposed to work. The authors of the study show that although intended edits can be made with respectable efficiency, such as correcting a mutation in a gene that causes blindness in mice, there are also unintended secondary edits made to the genome.

This may seem like a bombshell report, but it's a matter of optics. Researchers have never shied away from the reality that CRISPR gene editing tools can stray off target and make unintended edits to genomes in mammalian cells (i.e., humans). Many labs -- including Editas Medicine, CRISPR Therapeutics, and Intellia Therapeutics -- are working on increasing the efficiency and specificity of the technology. This is how science works. By quantifying these off-target mutations, which the paper attempted to do, researchers can begin to better understand how to improve the technology.

Investors and traders did not take the same cool-headed approach to the news, instead giving into a knee-jerk reaction to adjust the value of each pre-clinical technology platform. While off-target edits could prove troublesome for a CRISPR therapeutic used in humans, it's important to remember that there are currently no clinical trials underway in the United States. Editas Medicine will become the first to initiate a clinical trial later this year.

The sharp contrasts in reactions from researchers and investors is likely driven by how CRISPR is perceived by the media. Unfortunately, there is a generous amount of hyped-up science journalism that sticks to simple narratives -- "CRISPR has arrived and will cure all diseases!" -- instead of more nuanced takes that give equal weight to each current obstacles and future potential facing an emerging technology. Just remember: Biology is never quite so simple.

The results from the study don't really change anything, except for bringing more attention to the already existent clinical risk inherent to the development of early-stage CRISPR therapeutics. There is still plenty of work and new technology left to be developed before gene editing fulfills its promise in treating and curing human diseases. Hopefully, this can be a long-term positive for investors in CRISPR stocks by forcing them to listen to the fundamental hurdles for the technology. Hopefully.

Maxx Chatsko has no position in any stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.

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Here's Why Editas Medicine Fell as Much as 15.7% Today - Motley Fool

Genetic engineering through click chemistry – The Biological SCENE

Gene therapy and a range of biological research rely on the efficient delivery of nucleic acids into cells through the process known as transfection. Most widely-used transfection approaches for mammalian cells rely on electrostatic forces, usually taking advantage of cationic reagents to bind to negatively-charged nucleic acids and form strong ionic complexes. Cells then grab these complexes and internalize them through a process called endocytosis. However, the concentration of positive charge in the reagents can kill cells, and some cellssuch as embryonic cells, neurons, or cells directly isolated from tissuedont incorporate the nucleic acids successfully.

Now researchers report a novel transfection technique, SnapFect, that relies on bio-orthogonal moleculesa class of chemically-reactive molecules that dont interfere with biological systems (ACS Cent. Sci. 2017, DOI: 10.1021/acscentsci.7b00132). The team designed nanoparticle liposomes carrying a bio-orthogonal ligand. When they add those fatty particles to cell culture, they fuse into the cell membrane within seconds, leaving the ketone ligand exposed on the surface. The team then packages the nucleic acids to be delivered in complementary lipid complexes decorated with oxyamines. When the oxyamine particles are added to the cells, these functional groups react quickly with the cell surface ketones. The membrane-bound nucleic-acid complex is then pulled into the cell via endocytosis, and the nucleic acid can be expressed. Its not based on electrostatics but on click chemistry, says Muhammad N. Yousaf, a chemical biologist at York University. Thats why basically every cell is transfected with the nucleic acid.

Commercial transfection reagents already bring in about $1.5 billion per year. Yousafs team compared SnapFect to two widely-used kits: Lipofectamine (Life Technologies) and ViaFect (Promega). SnapFect transfected cells with a 68% overall efficiency while the other two transfected 19% and 29%, respectively.

Yousaf launched a company called OrganoLinX that this month began selling SnapFect ($350 for 20-25 transfections). We focused on making [the kit] just as easy to use as other commercial products out there, he says.

Besides improving efficiency, researchers could also pre-treat one batch of cells to decorate them with ketones and then mix them with other cell types before adding nucleic acids. Just the pre-treated ones will be transfected, Yousaf explains. Its like precision transfection. Because the team can create a variety of complexes using the oxyamine particles, the technique can also deliver other molecules such as proteins into cells.

I think its an interesting step forward, says James H. Eberwine, a molecular neurobiologist at the University of Pennsylvaniaparticularly the techniques universal applicability to DNA, RNA, and proteins, as well as the specificity conferred by the click chemistry approach.

Eberwine adds that while the study compares SnapFect to two widely-used techniques, researchers often optimize those techniques for their particular applications and achieve much higher efficiencies than those noted in this study. I would certainly try it, he says, and if it really does have the higher efficiency then I could see value in doing this.

Currently cell surface modification with ketones must occur shortly before addition of the oxyamine-bundled cargo. But SnapFect would be especially powerful if the ketone modification was more permanent, Eberwine says. That way, researchers could pre-engineer the surface of immature cells, then allow those cells to develop, migrate, and find their place in the local microenvironment of an experimental system before they get transfected. This would be a real boon, he says.

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Genetic engineering through click chemistry - The Biological SCENE

Aaron Rodgers: OTAs are for building on-field chemistry – Packers Wire

Building chemistry with his new teammates remains the primary goal for Green Bay Packers quarterback Aaron Rodgers during organized team activities, which continue into the second phase this week.

I think at this point, when youre adding new guys to the mix, its about chemistry, Rodgers said last week. Thats the on the field chemistry. Its reading body language when theyre running routes, its getting on the same page with the verbiage when you have new players. And starting to figure out how guys like to run routes, where they like the ball in certain situations, how they use their body. Its about timing, and getting that chemistry with the new skill players.

The Packers have added a number of new pieces to the offense this offseason, including veteran tight ends Martellus Bennett and Lance Kendricks. Green Bay also drafted two young receivers (DeAngelo Yancey, Malachi Dupre) and rebuilt the running back position.

Building a rapport and understanding each new individuals wants and needs is necessary for keeping a high-octane offense running smoothly. The connection between Rodgers and Bennett the versatile tight end and teams replacement for playoff hero Jared Cook is especially important for ensuring the Packers hit the ground running to start 2017.

The two have already been working overtime to establish the on-field relationship.

Im always talking to him on the field, too, trying to see what he wants, Bennett said, according to Jason Wilde of the Wisconsin State Journal. (Ill say), Hey, how did that look? or hell give me the thumbs up. Or if Im in another group, I always look back at him, Hey, is that what you want? Is there something different you want on this? Always trying to figure out, just trying to have those conversations on and off the field, trying to get know each other as players, and as people.

Kendricks,who spent his first six years with the Rams, is also using OTAs to find his footing in a new environment.

New organization, new offense, new verbiage, new schemes and stuff, Kendricks said. Its going to take a little bit of time, I just gotta take it day-by-day. But Ill catch on.

The new tight ends still have ample opportunity to get on the same page with Rodgers and comfortable within the offense, especially considering the Packers emphasis on the passing game during OTAs.

Chemistry is really important, Rodgers said. Its about learning those guys, and their body movements, and what routes they feel good about and what routes they struggle with. Well have plenty of time, in these OTAs, a lot of individual time. Were not doing a lot of run plays, by design. It gives us a lot of time to work on the passing gameIm confident well be ready to go once the season starts.

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Aaron Rodgers: OTAs are for building on-field chemistry - Packers Wire

Open Letter to the President: Yes, YouAre Probably Being Spied On – Canada Free Press

Continued below... Team Bauerle

As previously reported by Canada Free Press (CFP), after I was called a lunatic and worse in January 2014 and beyond, a war hero friend and I put together a team of patriots to help me prove what sounded crazy even to me: that I was and had been under illegal surveillance, that it was very high tech and that I was right all along. It was known as Team Bauerle.

This team I put together to prove my claims of being under surveillance consisted of retired SEALS, Delta Force, Green Berets, intel (CIA) and law enforcement pros, both active duty and retired.

This team disbanded after they made contact with the people conducting the illegal surveillance, who assured my people that I would be compensated for the anguish through which I had been put.

After believing the matter resolved, my Team Bauerle disbanded, but the surveillance continues, in violation of what I thought and was assured was an agreement we had privately reached, that has not been honored, despite my repeated entreaties.

I held back photos and videos in the interest of what I was told was national security.

Until now.

Since the publication of the CFP article Radios True Patriot, another loved one has received calls from a military contractor with contracts with the NSA.

Nothing was saidNo message was left.We have tried to call the number but despite being listed as a landline, it is a cell number and no one ever returned our calls to tell us why they had called my loved-one, twice without leaving a message (we have screenshots).

Was it some kind of veiled threat?

I dont scare.

In fact, I take it as a compliment that more than one person had told me that I reminded them of the Billy Bob Thornton character in Goliath. The authenticity of these photographs I am allowing CFP to publish of cloaking-invisibility technology in use in my own backyard has been confirmed byRichard Schowengerdt,the man who invented invisibility in the 1990s.

The first picture is a simple cell phone shot of my backyard, in daylight.

But what is that midway up the utility pole, to the right?

I invented a process to break the invisibility camouflage, and Ive never even taken a physics class.

Persistence.

And being more than a little pissed off.

Again, I now believe Team Bauerle was lied to in Spring 2016, and that the people illegally surveilling me were stalling to delay me or prevent me from pursuing a public course of action with the video and these (and many other) photos.

Mr. President, I now believe there is a high probability that those engaged in the harassment of me and several loved ones and friends are operatives of the Shadow Government trying to bring you and your presidency down. The reason I asked CFP to report on what I reasonably believed was a settlement that would be honored with those responsible for the illegal surveillance? (see CFP Vindicated)

Among other weirdness, a loved-one had received a butt-dial mystery call from April Melody of the DNC. (See pic from CFP)

I do not trust the Clintons or the Obama Mob, and I wanted that call and my story on the public record, lest I have a sudden heart-attack induced by hacking my ICD, or a lightning strike, or have my vehicle suddenly accelerate and crash.

This call to my loved ones cell phone was made hours after Hillarys DNC convention acceptance speech, and the person who received the call would have no reason to be on any DNC call list.

We learned the number belonged to Ms. Melody of the DNC because it was part of the Wikileaks dump.

Why would this person, very close to me, receive a call from a DNC staffer on the Wikileaks dump?

I left messages for her. She never returned my calls. How about that? Huh? President Trump, I have tried reaching out to you through mutual friends, but I have recently realized that even you may not know about the surveillance techniques under development right now, because no one from the White House ever got back to me.

One of your closest aides had no idea of my situation when it was brought to his attention.

I am concerned about you and believe it a strong possibility that you are being kept in the dark by Obama holdovers at the FBI, NSA and CIA because they WANT you to look like a paranoid lunatic.

Has anyone in our government advised you not to upset the intelligence apparatus, Mr. President?

I believe we are not just talking about the Obama progressives currently employed in intel, but those who may be doing private contract work after leaving the service.

I have decided to release these photos,with many more to come, complete with instructions on how to defeat these technologies, to help keep you safe.

If, as Commander in Chief, you request I not release additional photos and videos of this technology in action, I will obey, Sir.

Isnt it odd how many of your PRIVATE conversations were leaked to certain people?

With all of the leaks from your inner circle, there is something rotten going on.

President Trump, The Swamp is a bitter enemy and they will do anything to drain you.

You, President Trump, need to watch your back and I call upon you to open a federal probe of the illegal surveillance of citizens like me, and as you Tweeted, even yourself.

Former President Carter also believed that he was being illegally surveilled, but I suppose hes just delusional too, huh? And lets not forget the previous administrations illegal surveillance of Sharyl Attkisson and James Rosen.

I have a lot of intel to give you as a starting point.

Did I sound like a lunatic when we spoke? I hope not.

Did you sound like one to me? No.

But something is very, very suspicious.

I have concluded the people who have illegally surveilled me (and loved ones) since at least 2013 and who continue to do so, hacked my electronics as well as those of my loved ones and friends (like former White House Travel Chef Tracy Martin, whose phone was hacked and had his home broken into days after appearing on my show to confirm that the real Hillary Clinton has no use for our black brothers and sisters and frequently uses the N-Word.) are most likely Deep State people and those who simply cannot accept the fact that you beat The Swamps choice. (See: Tom Bauerle: Can Satellites Reprogram Voting Machines?, and DNC intimidation of Tom Bauerle loved ones exposed by Wikileaks)

Naturally, a significant amount of money will be needed to compensate me for massive invasions of privacy and my civil rights.

My home, despite having a state of the art security system, has been broken into on numerous occasions.

One such break-in was recorded in January 2014, and a professional came to my home, watched the video and informed me that it looked like electronic cloaking, a term of which I had never heard.

That professional? A Federal Agent Specifically, Secret Service.

We became acquainted when he reached out to me to request I make it clear that the Secret Service monitored comments made by listeners on my shows Facebook page, and requested that I remind people that the Secret Service investigates all potential threats. Of course, I happily obliged, as the Secret Service has better things to do than chase down idiots who vented violently against Mr. Obama.

I will not publicly name that person at this time.

On a subsequent visit to my home, he told me It looks like they have the full array against you tonight.

That individual gave me a box of chocolate from President Obamas Air Force One. (see photo, left)

We would meet periodically until one day he kind of vanished from the face of the earth, not only with me but also from a mutual friend.

It isnt a question of national security any more.

The issue is freedom and the republic.

What else makes sense?

We have been subjected
to years of civil rights violations as well as privacy violations.

Yes, this letter to you may cost me my job (Why would you bring this up again? I might affect the Almighty Revenue stream if people think youre nuts! I can almost hear it now), but there comes a time when people have a right to know what their government, research institutions and military contractors are up to.

And I will be litigating against ALL involved.

We should be talking about a MAJOR amount of compensatory and punitive damages here.

I believe the only reason I am alive is because of Team Bauerle and the info we gathered on them and their operation which dates at least back to 2013.

I can play the intel games with the best of them, and am damned proud of how I have withstood threats, implied threats and too many coincidences to be random.

There are waay tooo many such coincidences for me to stay quiet any longer.

And to other members of the media and left-wing bloggers who are salivating over the chance to question my sanity again, a la Alinskys ridicule, is a powerful weapon theory.

You would do quite well to refer to the statement by Dr. Marshall (Canada Free Press) attesting to my sound mental health. Mr. Bauerle does not need psychotropic medication.

My attorneys and I will vigorously pursue any unfair injury to my brand which may arise from false accusations that I have delusions or any such mental health issues.

I do not, and never have.

Youre on notice: youd best think twice before you call my sanity into question, and you may wish to reflect on the multiple corroborations of my claims by private citizens and the inventor of the technology, the above mentioned Richard Schowengerdt, who confirmed the photo below as proof beyond any doubt that I was correct about being under high tech surveillance.

I believe in the First Amendment, but I will not allow my reputation to be unfairly slandered or libelled and will be aggressive in pursuing any such damage to my brand.

You are put on notice: while I am a public person, and slander and libel claims have to meet a higher threshold to be actionable, my attorneys and I will have a keen eye on media outlets and their reporting on this, and will vigorously pursue any hint that I am mentally ill or delusional.

I am not an attorney, but you would be well-advised to speak with your legal counsel about the reckless disregard for the facts standard and ask yourself If a jury sees these pictures, the unambiguous corroboration from the man who invented cloaking technology they show , the statement from Dr. Marshall attesting to my sound mental health, what would the preponderance of evidence suggest? That I have mental issues, or that I am and have been telling the truth. So as much as it may pain you, I am very aware of the law in this regard.

And I just need 51% proof, even though it is my opinion as a layman I can exceed reasonable doubt in any claim. Choose your words very, very carefully when describing my claims.

Ill be happy to undergo a polygraph. And any ad hominem attack regarding my mental health will be dealt with appropriately. That isnt a threat. It is a promise, and Im doing you a favor in advance. I did not and will not pursue any action against the Amherst Police Department, because I respect law enforcement, and as I have stated, at that time I was making claims without substantiation. In their shoes, I also would have wanted a psych-eval. You members of the media and bloggers will receive no quarter at all from me should you recklessly disregard the facts of my case. Not just corporations, but individual reporters and bloggers work will be scrutinized carefully for any damage done unfairly to my brand and future income potential.

Meanwhile, heres the thing: The personal safety of truth-tellers is left hanging perilously in the balance.

If they can do this to the duly elected President of the United States, whats to stop them from doing it to the rest of us.

Continued here:
Open Letter to the President: Yes, YouAre Probably Being Spied On - Canada Free Press

14 Hopes For ‘Grey’s Anatomy’ Season 14 – Wetpaint

12. More standalone episodes

Yes, we love seeing all the docs every week, but the standalone episodes of Season 13 the ones focusing on just a few docs, at most were some of the most interesting installments.

Yes, yes, weve seen it all plane crashes, ferry crashes, earthquakes, mass shootings. Just accept the fact that Shondaland Seattle is the most catastrophe-ridden place on the planet and the fact that the disaster episodes are some of the most thrilling, memorable episodes.

We dont need these tragedies to kill off any surgeons R.I.P. Lexie and Mark. The mortal danger itself is captivating enough.

Yes, yes, weve seen it all plane crashes, ferry crashes, earthquakes, mass shootings. Just accept the fact that Shondaland Seattle is the most catastrophe-ridden place on the planet and the fact that the disaster episodes are some of the most thrilling, memorable episodes.

We dont need these tragedies to kill off any surgeons R.I.P. Lexie and Mark. The mortal danger itself is captivating enough.

Weve long since accepted that Greys Anatomy will outlive us all, and the show has proven its staying power. Season 13 held the shows quality and popularity steady, and were sure Season 14 will, too.

Plus, a 15th season puts it one season away from beating ER as the longest-running primetime medical drama in America. #goals

Weve long since accepted that Greys Anatomy will outlive us all, and the show has proven its staying power. Season 13 held the shows quality and popularity steady, and were sure Season 14 will, too.

Plus, a 15th season puts it one season away from beating ER as the longest-running primetime medical drama in America. #goals

Shonda Rhimes and her cabal of writers will soon be getting back to work to plot out Greys Anatomy Season 14 if they havent already and as fans of the show since 2005, we have high hopes for the drama to come.

In fact, weve written down those hopes to not-so-humbly submit them for consideration.

Check out the photo gallery here to see why we want Maggie and Jackson to hook up, why we want another disaster to strike Seattle, and other probably-controversial desires for Season 14.

Greys Anatomy returns for Season 14 this fall.

See more here:
14 Hopes For 'Grey's Anatomy' Season 14 - Wetpaint