College of Charleston chemistry professor explains how sunscreen … – Moultrie News

Most everyone knows to protect their skin from direct sunlight in the summer. But do you know how sunscreen works and whats actually in the stuff youre lathering all over your skin?

Tim Barker, an assistant professor of organic chemistry at the College of Charleston, answers some questions concerning ingredients in sunscreen and tries to separate the science from the hype.

Heres what he had to say:

Q: What chemicals are used in most sunscreens, and how do they work to protect us from damaging rays and from getting sunburns?

A: Both inorganic and organic chemicals serve as active ingredients in sunscreens. The inorganic compounds, titanium dioxide and zinc oxide, work by reflecting the radiation. The organic chemicals, two examples include avobenzone and oxybenzone, absorb the UV radiation with their chemical bonds before it interacts with the skin.

Q: What are some of the other applications for these same chemicals?

A: Zinc oxide is used in many things, but the most common use is in the vulcanization natural rubber into the rubber found in tires and other materials. Zinc oxide also has antibacterial properties so it has many medicinal uses.

Most of the organic compounds used as active ingredients in sunscreen are also used for sun protection in hair products and cosmetics.

Q: What should someone look for in a sunscreen for maximum protection?

A: It is important to use a sunscreen with active ingredients that protect against UV-A and UV-B rays. Avobenzone (organic) and zinc oxide (inorganic) are the only two active ingredients approved by the FDA and currently in use that protect against UV-A rays. Some studies with avobenzone and other organic chemicals used as active ingredients have suggested that these compounds may be endocrine disruptors. Especially for young children, zinc oxide would be the better active ingredient.

Q: What about sunscreen substitutes? Can natural ingredients whipped up at home provide protection against the sun?

A: The best natural sun protection would be to wear a hat and long sleeves. I would be wary of natural sunscreen ingredients. All natural ingredients are still chemicals.

Q: As a chemistry professor who can read a sunscreen label and actually know what the listed chemicals are, what type of sunscreen do you use?

A: I look for sunscreen with both UVA and UVB protection. Typically it will be SPF50 and contain zinc oxide which protects against UVA and UVB light as well as several other active ingredients.

Q: The U.S. Food and Drug Administration is investigating the efficacy and safety of spray-on sunscreens. Why would aerosol sunscreens be of particular concern?

A: When being exposed to a chemical there are different risks associated with the type of exposure. When you use a lotion, absorption through the skin is the main route of exposure. The aerosol sunscreens introduce inhalation as a route of exposure that has not been as well studied as absorption through the skin. If you like aerosol sunscreen, just spray it on your hand to apply it to your face to avoid inhalation.

Q: Have you ever had a bad sunburn? What went wrong?

A: I have gotten a sunburn at the beach when I did not reapply sunscreen after spending a lot of time in the water. The terms waterproof and water-resistant are really just marketing ploys on sunscreen bottles. The FDA has cracked down on the use of waterproof on sunscreen containers and made companies qualify how long a sunscreen is water-resistant since then, but I found out the hard way.

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Chemistry Professors Promote Cycling and Transit, On and Off Campus – CSUN Today

Avid cyclists Kayla and Mike Kaiserhave been married for 10 years and share a passion for health and public service, which inspired their nonprofit organization, BikeCar101.

As professors at California State University, Northridge in the Department of Chemistry and Biochemistry, the pair promote travel by train and bicycle to increase environmental sustainability and public health.The couple has been commuting to campus via Metrolink and bikes since 2013.

Over the past few years, the Kaisers have seen a growing interest in public transit and healthier commutes among CSUNstudents, professors and others in the workforce, they said. According tometro.nets active mode of transportation page, they state that, Active transportation improves public health by providing more opportunities for physical activity and safe places to walk, bike or travel by other human-powered means improves access to transit and provides more travel choices.

We were on the same [Metrolink] line with other professionals, and wed start bringing our bikes on there, Mike said.They saw us bringing our bikes [to campus to ride together], and they started to bring theirs.

He also pointed out that students are the biggest advocates for sustainability and alternative modes of transportation.

Ultimately, students have the greatest voice in change with respect to where the university heads toward sustainability, Mike said. Thats powerful. I cant overstate that.

The nonprofit BikeCar101 promotes using alternative forms of transportation, such as traveling by train and biking to destinations.The Kaisers hope to lobby the Metrolink Board to add additional Metrolink Bike Cars with more bicycle stalls for greaterbicycle storage. In the future, the Kaisers hope to expand theirlobbying efforts toward theMetro Transit Agency tofollow Metrolinks Board initiativeand provide a dedicated Bike Car to each Metro light rail train.Similar to what Amtrak does with its Surfliner line.

We rode the train with a group of about five commuters with bicycles, and there was only enough room for three bicycles, Kayla said. The conductor started to give us a hard time [because we had] too many bicycles, so I said, Weve got to petition the transit agencies for more space.'

BikeCar101 uses the 3T Program to educate those who need help riding Metrolink and need help mapping their destination. According to BikeCar101s website, the 3T program is about educating the public about bringing bicycles on board Metro rail and Metrolink trains to encourage them to engage in future active transportation.The nonprofits 3T Program provides the three Ts a t-shirt with BikeCar101s logo, a train ticket to the transporters destination, and that the transporter provides a testimonial for their website.The user does not have to pay for their ticket, all the nonprofithopes is that they educate someone else from this program.

The pair is determined to promote carbon-neutral travel and use secondary forms of transportation to get around town.

We wanted to improve the environment, live in a more sustainable fashion, Mike said. [Incorporating] a bicycle into our commute with a train relieves the stress of driving. Its amazing what a stress reduction it is when you dont have to drive, and you get your workout through a bicycle.

Riding the train also helps the community interact,Kayla added.

Rather than being stuck in a car, or by yourself, you can chat, catch up, meet new people, talk about current events or what youre doing this weekend, Kayla said. It makes for a nice community, [and] its a lot more friendly and relaxing.

For more information about BikeCar101, please visit theirwebsiteat https://sites.google.com/site/bikecar101test/.

BikeCar101, bikes, Chemistry and Biochemistry, chemistry professors, Sustainability, Wellness

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In ‘Last Train to Nibroc,’ a chance encounter leads to lifelong chemistry – Press Herald

Deertrees new repertory company is getting the theaters season rolling with Arlene Huttons Last Train to Nibroc, a touching story that follows two strangers and their intertwined journey through life after a chance meeting on a train in 1940.

Nestled in the foothills of western Maine, the rustic 1930s playhouse offers a picturesque location for the intimate two-actor production, directed by artistic and executive director Andrew Harris. The exposed wooden beams and on-site refreshment shop, the Salt Lick Caf, recall a bygone era that sets the mood for the plays rural Kentucky locale.

The production is stripped down, with two benches serving as the primary props for the two-act, three-scene performance. The minimalistic set shifts the audiences focus to the actors and the plays endearing storyline.

Emily Grotz and Luis Del Valle star as May and Raleigh. When the pair meet, May is a young woman returning home to Kentucky from California, her hopes of marriage dashed after being jilted by her soldier fianc. Raleigh dreams of going to New York City to be a writer, desperate to rebuild his life after being prematurely discharged from the service for fits that make it impossible for the young pilot to fly in the war.

Last Train to Nibroc uses the train as a metaphor that carries into the characters lives. Like the two dead writers Nathanael West and F. Scott Fitzgerald who are being transported by the train to their final resting places, Raleigh fears that he is hurtling toward his final destination in life. Upon meeting May, his view shifts and he begins to see opportunity in stops along the way. But May, a wannabe missionary, has a tendency to be judgmental, as demonstrated by her harsh recollection of her fellow passengers on the train.

Grotz and Del Valle, both theater majors at the University of Southern Maine, embrace their characters and the plays symbolism with a heartwarming maturity. Real-life chemistry seems to emanate from the two as their characters verbally spar onstage. Grotz brings just the right amount of sanctimoniousness to her otherwise good-hearted character, and Del Valle matches her with a winsome boyishness as his character playfully chides and teases May.

The pair are pure fun to watch when May, now a teacher of 51 students, tries to correct Raleighs grammar, which has become atrocious since moving back to his parents farm in the South. Its a witty battle of seen versus saw, with Raleigh delivering a series of digs that delightfully challenge Mays suppositions.

Over the half-year time span of the play, the two characters grow, solidifying the bond struck when they first met on the train. The actors bring out this blossoming maturity, delivering a tenderness that is sincere.

Deertrees Theatres Last Train to Nibroc is an engaging love story that embraces the ups and downs of life with humor and tenderness. It also serves as a gentle reminder to avoid judging by appearance or assumption. As May comes to discover about Nibroc, a festival in her hometown, preconceived notions often hinge incorrectly on our view of the world or in this case, word order.

April Boyle is a freelance writer from Casco. She can be contacted at:

[emailprotected]

Twitter: ahboyle

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In 'Last Train to Nibroc,' a chance encounter leads to lifelong chemistry - Press Herald

University community mourns the death of Mary Thompson, CSJ, ’53, professor emerita – St. Catherine University (press release)

Professor emerita Mary Thompson, CSJ (Sister Gertrude), died on Sunday, June 25, 2017, at age 89. A St. Catherine University alumna, class of 1953, she was a professor of chemistry at the University from 1964 to 2000.

Mary attended St. Kates after graduating from Visitation High School. In 1949, she joined the Sisters of St. Joseph of Carondelet and was given the name Sister Gertrude. She took her first vows in 1952, and her final vows in 1958. During that time, she earned her bachelors degree in chemistry from St. Kates, where she became a member of the Phi Beta Kappa honor society. She went on to earn a masters degree in chemistry at the University of Minnesota and a doctorate in chemistry from the University of California, Berkeley.

Marys teaching career began at Derham Hall High School in St. Paul, where she was a science and mathematics teacher. In 1964, she joined the faculty at St. Kates, teaching chemistry and natural sciences. She was promoted to associate professor in 1969 and to full professor in 1978. She served as chair of the chemistry department 19691990 and as Endowed Professor of Science 19861989.

Under Mary's leadership, chemistry at St. Kates was strengthened through grant-funded acquisition of modern scientific instrumentation, the inclusion of undergraduate research as an integral part of the curriculum, and American Chemical Society verification of the chemistry major.

Recognized by her students and colleagues as a superb role model for women pursuing science careers, Mary challenged students to engage in demanding research projects and to continue their education at the graduate level. She received many research fellowships, which enabled her to maintain an active scholarly life. Her work as a teacher and mentor set the stage for St. Kates increasing commitment to preparing women scientists.

Mary was a finalist for the Council for the Advancement and Support of Education Professor of the Year award in 1984 and, in 1997, received the American Chemical Societys Award for Encouraging Women into Careers in the Chemical Sciences.

Upon her retirement in 2000, she was given the title of faculty emerita. That same year, alumnae and friends of St. Kates chemistry department established the Sister Mary Thompson Scholarship to honor her dedication to women in science. The scholarship provides assistance to a St. Kates student pursuing a degree in either chemistry or pre-medicine.

During St. Kates 100th anniversary celebration in 2005, Mary was named one of the Centennial 100 for her influential role in the Universitys history and development.

Her hobbies included calligraphy and playing piano and cello. In retirement, she wrote grants for the CSJ Ministries Foundation and served as the treasurer of the CSJ St. Paul Province.

Mass of Christian Burial was held on July 5, 2017 in Our Lady of Presentation Chapel in St. Paul, Minnesota.

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University community mourns the death of Mary Thompson, CSJ, '53, professor emerita - St. Catherine University (press release)

Nanotechnology Now – ECHA Announces Two Decisions on … – Nanotechnology News

Home > Nanotechnology Columns > Bergeson & Campbell, P.C. > ECHA Announces Two Decisions on Appeals Related to Nanomaterials

Abstract: On June 30, 2017, the European Chemicals Agency (ECHA) Board of Appeal published two decisions related to nanomaterials.

July 6th, 2017

On June 30, 2017, the European Chemicals Agency (ECHA) Board of Appeal published two decisions related to nanomaterials. In the July 5, 2017, issue of ECHA Weekly, ECHA states that the Board of Appeal "largely upheld the appeals and annulled most of the requests for information." See https://echa.europa.eu/view-article/-/journal_content/title/echa-weekly-5-july-2017 In Cases A-014-2015 and A-015-2015, registrants appealed the same 2015 ECHA decision requesting information on synthetic amorphous silica (SAS) following a substance evaluation by the Netherlands Competent Authority. See https://echa.europa.eu/web/guest/about-us/who-we-are/board-of-appeal/announcements/-/view-announcement/301/search/true and https://echa.europa.eu/web/guest/about-us/who-we-are/board-of-appeal/announcements/-/view-announcement/302/search/true ECHA requested information on the physicochemical properties and uses of different types of SAS and surface-treated SAS. According to ECHA, the Board of Appeal annulled these requests "as it was not clear how the information would be used to clarify the potential concerns which in any case had not been sufficiently demonstrated." ECHA notes that the Board of Appeal upheld one request in the contested decision -- for information on the inhalation toxicity of one type of SAS, following repeat exposure.

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Neurologist Dr. Douglas A. Woo joins O’Bleness Hospital staff – Parkersburg News

ATHENS Neurologist Dr. Douglas A. Woo will join the OhioHealth OBleness Hospital medical staff on Wednesday.

Woo is a board-certified neurologist specializing in multiple sclerosis. Additionally, Woo treats the full range of neurology, including dizziness, stroke, seizure, dementia and head/neck pain. He also provides botulinum toxin injections and myofascial trigger point injections to treat selected variants of headaches and neck pain.

Woo received his undergraduate degree from Marquette University and his medical degree from the Medical College of Wisconsin, both in Milwaukee, Wisconsin. He also completed his internship and neurology residency at the Medical College of Wisconsin. He completed a fellowship at the University of Texas Southwestern Medical Center at Dallas focused on the treatment of multiple sclerosis. He is a member of the American Academy of Neurology.

ATHENS - Authorities in Athens County have identified a Meigs County man as the kayaker missing since Saturday ...

A power interruption originally scheduled for Monday has been canceled because of the efforts to restore power ...

PARKERSBURG The Ohio River Valley Water Sanitation Commission has elected Stuart F. Bruny of Logan, Ohio, as ...

PARKERSBURG A familiar face has returned to the Blennerhassett Hotel. Yancy Roush has been hired as the new ...

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Neurologist Dr. Douglas A. Woo joins O'Bleness Hospital staff - Parkersburg News

Immune-matching process improved, reports Human Longevity-led study – The San Diego Union-Tribune

A team led by researchers at La Jollas Human Longevity reports developing a faster and more accurate method for determining immune type. The method will speed up immune matching for organ transplant and other purposes such as treating infectious and autoimmune diseases, the scientists say.

The method characterizes a region of the genome called human leukocyte antigen, or HLA, that regulates the immune system. Located on Chromosome 6, this region contains a high number of short, repetitive DNA sequences.

Because these repeats are so similar, placing them in the correct order is difficult. So even when people have their genome sequenced, the precise HLA type may not be clear. People can have HLA typing done separately, but that adds time and expense, said J. Craig Venter, one of the studys authors.

The study was published July 3 in the Proceedings of the National Academy of Sciences. Go to j.mp/humanhla for the study. Venter was senior author. The first author was Chao Xie.

The Human Longevity-led team invented an algorithm called xHLA to read these sequences correctly. Results are available within about 3 minutes from a desktop computer, instead of several minutes or even hours, the study stated. Moreover, the method helps identity potential matches that purely DNA-based methods would miss.

Making HLA typing a routine part of sequencing will help doctors advance the practice of precision medicine, the study stated.

For example, autoimmune disorder patients often have chronic problems with no exact diagnosis for many years after repeated doctor visits, the study stated. Knowing patients HLA types could lead to early diagnosis and reduce the burden on both patients and the healthcare system.

Venter said Human Longevity now offers HLA typing as part of its genome sequencing service. And in the future, this technology will be omnipresent and in the hands of patients.

If a family member needs a kidney transplant, you can just look it up on your iPhone and compare the sequences, and everybody will know immediately if theres a match in the family, or other places, Venter said.

Popular sequencing technologies cut up DNA into short pieces for sequencing. These pieces are reassembled by computer like an electronic jigsaw puzzle. But the many repetitive components in HLA can fool the computer programs, like similarly shaped or colored jigsaw puzzle pieces can do to a human.

The xHLA algorithm works with sequencing technology from Illumina to improve accuracy. An important component of the algorithm is that it examines the sequence of amino acids the DNA codes for, the study said. This helps accuracy by accepting DNA variations that happen to code for the same amino acid.

Since immune compatibility is determined at the protein level, using these synonymous variations produces a more accurate result than typing by DNA alone.

The problem with DNA-level alignment is that it cannot distinguish synonymous from nonsynonymous mismatches, the study stated. For example, it will rank five synonymous mismatches as more dissimilar than a single nonsynonymous one.

bradley.fikes@sduniontribune.com

(619) 293-1020

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Chf albumin lasix – Lasix name meaning – Van Wert independent

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LIMA Employers in the greater West Central Ohio region will collect $33 million in rebates from the Ohio Bureau of Workers Compensation in checks that will be mailed beginning next week.

BWC Administrator/CEO Sarah Morrison, in Lima to present a ceremonial check to local business leaders, said employers are free to spend their rebates as they wish, but she hopes they will consider investing in workplace safety.

We work with employers all over Ohio to prevent injuries and illness in the workplace, and they will tell you that investing in safety is a wise business decision, said Morrison, speaking at a press conference at the Lima/Allen County Chamber of Commerce. Safe workplaces mean fewer injuries, fewer medical claims and a stable workforce, all of which leads to a healthy bottom line for a business.

Morrison was joined by chamber President/CEO Jed Metzger and Tony Daley of Limas Spallinger Millwright Services Inc. Metzger and Daley accepted the check on behalf of employers in the entire region, which includes Allen, Auglaize, Shelby, Hancock, Putnam, and Van Wert counties.

Ohio Gov. John Kasich proposed the rebate in March. Its the third such rebate in the last four years, made possible by an improving safety climate, prudent fiscal management and strong investment returns. The plan to distribute rebates to more than 200,000 Ohio employers during the month of July was approved by BWCs Board of Directors in April. Visitbwc.ohio.govfor more details and eligibility requirements.

The plan also includes a $44 million investment innew health and safety initiativesto promote a healthy workforce and a culture of safety in every Ohio workplace. This includes a new wellness program for small employers, funding for programs to help firefighters and those who work with children and adults with disabilities, and an education campaign to address common injuries at work and in the home.

A healthy economy depends on a strong and healthy workforce, Morrison continued. And when the economy is healthy, we all benefit.

Rebate checks will be mailed in phases starting July 10.

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Proof of God’s existence is on the streets of Kamloops – CFJC Today Kamloops

All my life, Ive been skeptical about the existence of a supreme being. I was raised an atheist, but drifted toward agnosticism quite some time ago.

I dabbled in studying a bit of religion while in university and it convinced me I just dont have the wherewithal, nor the blind faith, to get it. (Believe it or not, I still have the textbooks, two volumes of Christendom, A Short History of Christianity and its Impact on Western Civilization.)

But in the past couple of weeks, Ive become convinced there must be a God, or some higher level of intelligence or, at least, a higher level of control. A supreme CEO, perhaps.

The proof is on the streets of Kamloops. Every day, hundreds of drivers try to kill themselves on those streets and, every day, for the most part, they somehow escape.

They are so bad at what they do, these drivers, that they constantly put themselves and others in mortal danger. They are careless, unskilled and, in some cases, shockingly stupid.

The fact they do this day after day leads me to the conclusion that someone or something is protecting them, and it must be God. Nothing else makes sense.

Christian belief has it that God has given humans free will. Why he/she would do this, I dont know. Regardless, people have been given the blessing/curse of doing what they please without interference from above.

Theres a whole thing about whether free will is actually compatible with determinism, the latter suggesting theres only one possible outcome to an action. And then you get into side arguments about the actual meaning of free will and so on.

In my view, all you have to do is drive around town to find out what free will is, because people in cars exercise it moment by moment, and very often very poorly.

In just a couple of hours on Friday, while I was out and about doing some chores, I counted more than a dozen incidents that could have had disastrous consequences. They included a near collision resulting from someone ignoring I dont mean simply cutting it close, I mean absolutely ignoring a red intersection light.

In another case, a pedestrian nearly got clipped in a crosswalk. (The classically stupid move at crosswalks is for drivers to swing around another vehicle that is stopped when a pedestrian is crossing.)

Parking lots are notoriously dangerous places. I watched with fascination as somebody blithely sped across empty parking spaces, no doubt because it saved maybe two seconds getting from A to B.

And, of course, theres the pervasive phenomenon of texting and talking while driving, not to mention everyday speeding.

No doubt, you experience the same things on an average day. Multiply what you and I observe by the thousands of other drivers out there, and you can appreciate how amazing it is that people arent getting killed by the hundreds each and every day.

In China, they are 700 people a day die in road accidents there. India is only slightly less. In Canada, six.

Sure, those other countries have a lot more people, but still. Maybe God has a selective sense of humour. He/she lets all these drivers run amuck, and then saves them from themselves.

He (in the interests of brevity, at this point Ill dispense with gender-equity in referencing God but please accept that I have good intentions) plays a game of inches and milliseconds. Wed call it luck, but that seems too easy. We cant possibly be that lucky.

God created us to be in a hurry, to be careless and to ignore everything we learn in driving school. As Im writing this, Im having second thoughts about his sense of humour explaining whats going on.

Maybe he saves us from ourselves as atonement for messing up in the first place. He could have made us good drivers, but he clearly didnt foresee the age of the automobile, so now hes hit on a percentages scheme. For every 10,000 stupid driving tricks, he lets something bad happen. Otherwise, wed get suspicious.

Still, I find it reaffirming that, in my advanced years, God has at last revealed himself to me.

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Australia’s most religious and non-religious postcodes based on who answered the Census question regarding religion – NEWS.com.au

The latest Census release show those ticking "no religion" rose to 29.6 per cent, and for the first time in Australia's history it has overtaken Catholics. So are we becoming a nation of non-believers?

New South Wales has our most religious suburb, according to Census 2016 data.

AUSTRALIAS most religious and non-religious postcodes have been revealed in the latest Census data by the Australian Bureau of Statistics (ABS).

Ninety-three per cent of residents in the New South Wales postcode 2190, which encompasses the suburbs Greenacre and Chullora, in Sydneys south-west,stated they had a religious, secular or other spiritual belief, according to information consultants at the ABS.

The area has been identified as Australias most religious.

Nearly half (41.4 per cent) of the population claimed a religious affiliation to Islam and the same percentage spoke Arabic, while 23.1 per cent identified as Catholic.

Only 6.1 per cent stated they had no religion.

Also included were 11 people (0.04 per cent) who said they had a secular belief which the ABS said could include agnosticism, atheism, humanism, rationalism and others not classified.

According to Census stats, the most common ancestry of residents in the area was Lebanese (31.1 per cent), followed by Australian (10.1 per cent) and English (7.1 per cent).

While 53.3 per cent of residents were born in Australia, 68.6 per cent had both parents born overseas, with the highest percentage coming from Lebanon.

The figures were based on postal areas with at least 100 usual residents, and based on persons who answered the question regarding religion (which is not compulsory).

Census stats reveal an insight into Australias most religious postcode.Source:Supplied

A whopping 72.7 per cent of households spoke a language other than English, while the median age was 33 years old. Children aged 0-14 made up almost a quarter of the population. (24.1 per cent).

One of the suburbs, Greenacre, is home to Australias largest Islamic School, the Malek Fahd Islamic School, which is fighting to keep its federal government funding.

According to The Conversation, Muslims were almost entirely absent from many neighbourhoods and suburbs, and there were only a few (located in Melbourne and Sydney) where they made up more than 50 per cent of the population. This includes the neighbouring suburb of Lakemba.

Despite fears Australia is becoming a Muslim country, those ticking no religion in the Census has now overtaken the number of Catholics.

Its the first time in Australias history the number of people who claim no religion has overtaken Catholics, although the number of Christians in total still made up 51 per cent of the population.

The least religious suburb according to the ABS is found on the other side of the country, in a small, sleepy town in Western Australia with the postcode 6705, where 66.5 per cent of the population in Gascoyne Junction stated that they had no religion.

The area includes heritage-listed sites from early colonial Australian days and has a high proportion of indigenous people.

More than half (58.4 per cent) of the 278 people who live in the area, identified as Aboriginal or Torres Strait Islander.

Other suburbs that have been identified as particularly unholy include Melbournes terrace-lined North Fitzroy, while Fairfax is reporting Erskineville in Sydneys inner-west was now officially Australias most ungodly suburb.

Nationally, the latest Census drop showed those ticking no religion rose from 22.6 per cent to 29.6 per cent nearly double the 16 per cent in 2001.

Meanwhile, those identifying as Catholic dropped from 25.3 per cent to 22.6 per cent.

The number of Christians in total still made up 51 per cent of the population, but this is much less than the 88 per cent in 1966 and 74 per cent in 1991.

Islam (2.6 per cent) and Buddhism (2.4 per cent) were the next most common religions reported.

Those who did not answer the religion question, which is a non-compulsory question in the Census, was 9.6 per cent, up slightly from 9.2 per cent in 2011.

We remain a predominantly English speaking country, with 72.7 per cent of people reporting they speak only English at home. Tasmania had the highest rate of people speaking only English at home with 88 per cent, while the Northern Territory had the lowest rate at 58 per cent.

An earlier release of Census data in April showed the typical Australian was now a 38-year-old married woman with two children.

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Should Tyler Cowen Believe in God? – New York Times (blog)

A little while ago the prolific and intellectually-promiscuous Tyler Cowen solicited the strongest arguments for the existence of God, and then with some prodding followed up with a post outlining some of his reasons for not being a believer. I cant match Cowens distinctive mix of depth and pith, but I thought Id take the liberty of responding to some of his reasons in adialogic style, with my responses edited in between some of his thoughts. Nothing in here should be construed as an attempt to make the Best Argument for God, and the results are rather long and probably extremely self-indulgent, so consider yourself forewarned. But here goes.

*

Cowen:Not long ago I outlined what I considered to be the best argument for God, and how origin accounts inevitably seem strange to us; I also argued against some of the presumptive force behind scientific atheism. Yet still I do not believe, so why not?

I have a few reasons: We can distinguish between strange and remain truly strange possibilities for origins, and strange and then somewhat anthropomorphized origin stories. Most religions fall into the latter category, all the more so for Western religions. I see plenty of evidence that human beings anthropomorphize to an excessive degree, and also place too much weight on social information (just look at how worked up they get over social media), so I stick with the strange and remain truly strange options. I dont see those as ruling out theism, but at the end of the day it is more descriptively apt to say I do not believe, rather than asserting belief

The true nature of reality is so strange, Im not sure God or theism is well-defined, at least as can be discussed by human beings. That fact should not lead you to militant atheism (I also cant define subatomic particles), but still it pushes me toward an I dont believe attitude more than belief. I find it hard to say I believe in something that I feel in principle I cannot define, nor can anyone else.

Me:Perhaps, but since you raise the strangeness of subatomic particles you might consider a third possibility for thinking about origins: Alongside strange and remain truly strange and strange and then somewhat anthropomorphized, there might be a category that you could call anthropomorphic/accessible on the surface and then somewhat stranger the deeper down you go.

This often seems to be the nature of physical reality as we experience and explore it. When we work on the surface of things, the everyday mechanics of physical cause and effect, we find a lot of clear-seeming laws and comprehensible principles of order. When we go down a level, to where the physical ladders (seem to) start, or up a level, to our own hard-to-fathom experiences of consciousness, we seem to brush up against paradox and mystery. So up to a point the universe yields to our fleshbound consciousness, our evolved-from-apes reasoning abilities, in genuinely extraordinary ways, enabling us to understand, predict, invent and master and explore. But then there are also depths and heights where our scientific efforts seem to trail off, fall short, or end up describing things that seem to us contradictory or impossible.

And by way of analogy it might be that there is a similar pattern in religion and theology. The anthropomorphizing tendency that makes you suspicious, the ascription of human attributes to God and the tendency of the divine to manifest itself in humanoid (if ambiguously so) forms, the role of angels and demons and djinn and demi-godsand saints and so forth in many religious traditions all of this might just reflect a too-pat, too-anthopomorphic, and therefore made-up view of Who or What brought the world into being, Who or What sustains it. But alternatively and plausibly, I think it might represent the ways in which supernaturalrealities are made accessible to human perception,even as their ultimate nature remains beyond our capacities to fully grasp.

Which is, in fact, something that many religious traditions take for granted(the Catholic Church, for instance, does not teach that angels are really splendid androgynes with wings), something thats part ofthe architecture of ordinary belief (most people who habitually visualize God as an old man with a white beard would not so define him if pressed), and a big part of what the adepts of religion, mystics and theologians, tend to stress in their attempts to describe and define the nature of God.

Note, too, that this stress on surface accessibility and deep mysteryis not something invented by clever moderns trying to save the phenomenon of religion from its critics. It is present from ancient times in every major religious tradition, providing a substantial ground of overlap between them David Bentley Hart is good on this, in a book that offers a partial answer to the definitional issue you raise and in Western monotheism it shows up in such not-exactly-obscure places as the Ten Commandments (no graven images for a reason) and the doctrine of the Trinity. (You will not find something that better fits the bill of strange and remains truly strange than what the Fathers of the Church came up with to define the Godhead.) Or, for that matter, in the story of Jesus of Nazareth, who in the gospel narrativesis quite literally an anthropomorphic God, and then after his resurrection becomes, not a simple superman but something stranger sometimes recognizable and sometimes not, physical but transcending the physical, ghostly and yet flesh whose attributes the gospel writers report on in a somewhat amazed style without attempting to circumscribe or technically define.

Again, anthropomorphism is the initial layer, the first mechanism of revelation. The strangeness you understandably think is necessary for plausibility, given our limitations, lies above or down beneath.

Of course the analogy to Newtonian/Einsteinian physics breaks down in various ways, not least of which is that there is often a basic agreement among scientists about the first layer, the understandable and predictable and lawbound aspectsof the physical world, whereas the religious cannot agree upon (or conduct laboratory tests to prove) which anthropomorphic supernatural revelations are trustworthy and should control practice and theological commitment. Thus specific religious belief, as opposed to a general openness to the idea of God, tends to beeither intensely personal, culturally-mediated, probabilistic, or some combination thereof in a way that believing in the laws ofphysics is not. But that brings us to your next point

Cowen: Religious belief has a significant heritable aspect, as does atheism. That should make us all more skeptical about what we think we know about religious truth (the same is true for politics, by the way). I am not sure this perspective favors atheist over theist, but I do think it favors I dont believe over I believe. At the very least, it whittles down the specificity of what I might say I believe in.

I am struck by the frequency with which people believe in the dominant religions of their society or the religion of their family upbringing, perhaps with some modification. (If you meet a Wiccan, dont you jump to the conclusion that they are strange? Or how about a person who believes in an older religion that doesnt have any modern cult presence at all? How many such people are there?)

This narrows my confidence in the judgment of those who believe, since I see them as social conformists to a considerable extent. Again, I am not sure this helps atheism either (contemporary atheists also slot into some pretty standard categories, and are not generally free thinkers), but it is yet another net nudge away from I believe and toward I do not believe. Im just not that swayed by a phenomenon based on social conformity so strongly.

Me: Okay, butas you note the conformity problem exists with every human school of thought and inquiry, every moral and political theory of what is good and what should be condemned. We are always creatures of our time and place and parentage, and converts of any kind not only religious, but political and intellectual are by definition exceptional.

Yetthe cultural contingency of all beliefs does not prevent people from reasonably holdingfairly strong views about a lot of non-religious issues. So its not clear to me why it should requireagnosticism as opposed to humility in belief in religious matters either.

For instance: Does the fact that my heritage and cultural context inclines me to regard human life as sacred mean that I mustretreat to agnosticism about the moral status of the Shoah? (Nazis even more than Wiccans are strange these days, but that doesnt prove that anti-Nazism is just so much cultural prejudice.) Does the bias instilled by the fact they were mostly born and raised in a commercial republicmean that the faculty of George Mason should cease evangelizing on behalfof free-market economics? Yes, moral theory is unlike economics which is unlike theology, but in each case we have plenty of examples of people converted from one view to another by reasoned argument and so long as conversion is possible, the fact that most people dont convert is hardly a knock-out blow against the potential truth of one argument or another, and the value of holding at least provisional commitments.

Moreover just as arguments about moral theory and economics often work because they proceed from a basic conceptual common ground, so too do arguments in religion. Even if choosing a specific religion is a knotty problem, the various religions do have a lot of shared beliefs that supernatural realities exist, at least, and then beyond that commonalities in their ideas of God, and then beyond that in many cases a shared belief in certain revelations.

Your example of Wicca and my own Christianity are in some senses particularly far apart, but in other ways less so, since a Christian might reasonably regard Wiccan beliefs as not so much false as dangerous, touching on realities that might be real but are best left unexplored either because they might be demonic or because they are simply unseely, to borrow the language of the folklorists and poets. The Wiccan, meanwhile, might well have some sort of revisionist Jungian reading of the Christian gospels that incorporates them into her own cosmological picture. Overall, I do not find the Wiccan world-picture nearly as strange and implausible as I find eliminative materialism, and its perfectly possible to have a fruitful Christian-Wiccan argument even if we might have persecuted one another in the past just as its possible to have a fruitful argument between a constitutional monarchist and a republican even though the French Revolution wasa bloody affair.

So theidea that religious controversy is simply a clash of instilled habits, while certainly often true, need not be necessarily true, and (again as with other non-scientificquestions) isnt true when serious people debate the issues in good faith.

I would also add that in the present cultural context most of the believers that you, a professor and blogger, are likely to end up arguing with will be people whose religion is notat all simply an inheritance but rather something reasoned toward and held in defiance of intellectual convention, whereas your agnosticism is presently such an academic commonplace as to be its own form of conformism. It seems to me that by those premises you shouldnarrow your confidence in that agnosticism, and give religious commitment a slightly longer look.

Cowen: I do accept that religion has net practical benefits for both individuals and societies, albeit with some variance. That is partly where the pressures for social conformity come from. I am a strong Straussian when it comes to religion, and overall wish to stick up for the presence of religion in social debate, thus some of my affinities with say Ross Douthat and David Brooks on many issues.

Me: Ill take the affinities I can get though one possible religious response would be to reject this one, on the grounds that (to rip off Flannery OConnor) if its just socially usefulthen to hell with it. But thats not my take; instead, I think the fact that religion has net practical benefits (with some variance as you say!), and not only practical in some strict utilitarian sense but also aesthetic (that religiously-infusedsocieties produce better art and architecture is of course technically a de gustibus issue but come on, its true), is itself suggestive evidence for the claim thatreligious beliefs point to something real. One can come up with plenty of other explanations, but still, a harmony between religious ideas, human flourishing and great aesthetic achievement iscertainly consonant with the idea that we are restless until we rest in Him. And in a similar vein the claims from atheists that if we could pinpoint the evolutionary origins of religious belief we would somehow explain it all away always strike me as strange, because most evolved features of human nature evolved the way they did because they were adapted to some actual reality and why shouldnt the religious instinct be the same? But on to your next point

Cowen: I am frustrated by the lack of Bayesianism in most of the religious belief I observe. Ive never met a believer who asserted: Im really not sure here. But I think Lutheranism is true with p = .018, and the next strongest contender comes in only at .014, so call me Lutheran. The religious people Ive known rebel against that manner of framing, even though during times of conversion they may act on such a basis.

I dont expect all or even most religious believers to present their views this way, but hardly any of them do. That in turn inclines me to think they are using belief for psychological, self-support, and social functions. Nothing wrong with that, says the strong Straussian! But again, it wont get me to belief.

Me:Well sometimes believers dont present things this way because their religion is, as you say above, an inheritance rather than a chosen thing,and so they arent inclined to be Bayesian about it for the same reason that the average patriotic American doesnt give you percentages when you ask what system of government is best. And sometimes they dont because the practice of religion encourages a quest for a personal relationship with God, and once youve embarked on that kind of quest after perhaps making a calculation before you leap, as your point about conversion concedes you cant always be worrying aboutthe percentage odds that youre making a mistake. (There are similar issues in romantic love!)

But theres also plenty of apologetic literature, some of it crude and some of it sophisticated, that makes what amount to implicitly odds-based arguments: Everything from Pascals wager to C.S. Lewiss lunatic/liar/Lord trilemma falls into that broad category, and authors of varying religious traditions, past and present, are constantly making arguments for why their ideas are a better intellectual bet than Muhammeds or Luthers or Joseph Smiths or the Buddhas or whomevers. Indeed its onlyin contemporary liberal circles that these sort of arguments are considered ill-mannered and impolite which, again, might narrow your confidence that the agnosticism assumed in those circles is held for genuinely good, well-thought-through and well-defended reasons.

Also, as it happens, because Im a weirdo I mentally play this kind of Bayesian game with all myself fairly often. For instance, when people ask me what effect Pope Franciss maneuvering around divorce and remarriage might have on my confidence in Catholicisms truth, the answer is thata big enough shift would lead me to downgrade my belief in Catholicisms exclusive truth claims relative to other Christian confessions, and raise the odds that there simply is no One True Church and all the various confessions have pieces of the garment Jesus and the apostles left for us. Whether thinking along those lines is wise or pious is an open question, but oddsmaking definitely forms part of my mental religious architecture. And ifwatching me play the game might help convertyou(I doubt it, but Ill risk the embarrassment), Ill play it at the very end of our dialogue but first lets take up your last two points.

Cowen: I do take the William James arguments about personal experience of God seriously, and I recommend hisThe Varieties of Religious Experience: A Study in Human Natureto everybody its one of the best books period. But these personal accounts contradict each other in many cases, we know at least some of them are wrong or delusional, and overall I think the capacity of human beings to believe things some would call it self-deception but that term assumes a neutral, objective base more than is warranted here is quite strong. Presumably a Christian believes that pagan accounts of the gods are incorrect, and vice versa; I say they are probably both right in their criticisms of the other.

Me: My sense of things is that mystical experience tracks the pattern I noted above: Theres a commonality at the level of the ineffable, where mystics Western and Eastern, Christian and Sufi tend to sound somewhat alike in their descriptions of what they cant describe, and then theres diversity and contradiction when it comes to the more anthropomorphized encounters, where angels or the Virgin Mary or the God Krishna show up to deliver a vision or a message.

This diversity and contradiction is a good reason to be wary of founding your religious beliefs on any single persons experience or message, and it might be a case against dogmatism in religion, period. But I think even if you dont find any particular revelation convincing enough to let it control how you interpret the entire cosmos, a more parsimonious explanation than mass delusion and self-deception could still lead you reasonably to the forms of religious syncretism that were common in the pre-Christian world, to the pagan traditions that treat the gods of polytheism as personalized and localized manifestations of the Godhead, or to pantheism or gnosticism in their various forms. We see through a glass darkly, but the fact that we are all catching different glimpses of divinity should make us suspect that while the differences counsel humility, there really is something there to see.

And I would add that as a Christian I dont regard the pagan accounts of the gods as precisely wrong so much as partial, mythologized (often consciously and deliberately), and incomplete. There is nothing in Christian cosmology that precludes the Christian God manifesting Himself partially in non-Christian societies through mystical encounters that are experienced and interpreted in line with pre-existing beliefs, and indeed Christians (especially in the Catholic tradition) have in many case appropriated pagan traditions by treating them, in part, as providentially-intended preparations for Christianity.

At the same time Christians also believe as a matter of faith that there are other spiritual powers in the universe besides the Triune God, which allows for the belief that pagan accounts might reflect angelic or demonic encounters. And finally there is also nothing in Christian cosmology that precludes the possibility of other forces besides angels and demons. In the early Old Testament its quite a while before the Israelites discover, as it were, that the God speaking to them is different in kind rather than degree from other gods; nobody knows who the Nephilim were; belief in ghosts is as common in Christian cultures as in others; medieval and early modern Europeans often treated the realm of faerie as a kind of third space, a nonaligned spiritual territory, and in some cases explicitly re-read and rewrote their ancestors pagan traditions as faerie stories.

These kind of attempted reconciliations are obviously unnecessary if you dont accept the Christian revelation. My point is just that even if you do, the possible validity of a range of diverse and contradictory-seeming religious encounters doesnt have to go out the window. Indeed even when encounters happen completely under the metaphysical canopy of Catholic belief, the church itself can still end up concluding as it seems to be with the mystics of Medjugorje that some of them are really heaven-sent and some are not, that the same person or group of people can have a real vision and then subsequently a false or made-up or misinterpreted one. Even where God seems to be breaking in or speaking unusually directly, the through-a-glass-darkly rule still applies.

Cowen: I see the entire matter of origins as so strange that the transcendental argument carries little weight with me if there is no God, then everything is permitted!We dont have enough understanding of God, or the absence of God, to deal with such claims.In any case, the existence of God is no guarantee that such problems are overcome, or if it were such a guarantee, you wouldnt be able to know that.

Me: This seems like an overstated response to an overstated claim. I agree, there are conceptions of the Absolute that would justify all sorts of (what we would consider) atrocities and conceptions of His non-existence that still persuade people to be moral realists rather than ax-wielding Raskolnikovs. But consider a more modest version of the argument: Namely, that the Judeo-Christian conception of the nature of God and the modern small-l liberal consensus on human rights and moral wrongs cohere together fairly well, as a picture of how the universe and moral universals interconnect, whereas that same liberal consensus is a much poorer fit with the de facto atheism and materialism of many of its present-day proponents.

I think this modest claim is simply, well, true: Schemes for a Darwinian ethics generally have a brazen artificiality to them when they arent leaping merrily toward tooth-and-claw, might-makes-right conclusions; in the genealogy of modern morals the Christian worldview is a progenitor of rights-based liberalism in a fairly straightforward and logically-consistent way; and the alternative syntheses are a bit more forced, a bit dodgier, and a bit prone to suddenly giving way, as the major 20th century attempts at genuinely post-Christian and post-liberal societies conspicuously did, to screaming hellscapes that everyone these days considers simply evil.

I concede that a worldviews coherence doesnt prove anything definitive about its truth. You can certainly preserve a preference for human rights or any other feature of the contemporary consensus on non-theological grounds. But in the quest for truth, coherence still seems like a useful signpost, and looking for its presence still seems like a decent-enough place to start.

Cowen: Add all that up and I just dont believe.Furthermore, I find it easy not to believe. It doesnt stress me, and I dont feel a resulting gap or absence in my life. That I strongly suspect is for genetic reasons, not because of some intellectual argument I or others have come up with. But there you go, the deconstruction of my own belief actually pushes me somewhat further into it.

Me: This is weak sauce, Tyler. Youve just complained about the ethno-cultural pattern in belief and why it makes you more skeptical of religious truth claims. If you think you have a genetic bias toward a happy agnosticism, shouldnt that sort of deconstruction make you more intellectually skeptical of your own irreligious conclusions, not less especially since, again, agnosticism in our own era comes with higher social status in the academic circles you inhabit than does actual religious commitment? The world is very strange, Im comfortable leaving it at that is not a conclusion you would accept in the debates to which you are personally-cum-genetically predisposed. Doesnt your willingness to accept it on this question, one whose great importance I hope you would be willing to concede, seems a touch what word should I reach for ah, perhaps complacent? Arent you manifesting the very vice you just spent a book critiquing, however gently, in your fellow Western Brahmins? Why not be the change you seek?

As I admitted above, the game that a man of your Bayesian temperament would need to play to get to some limited form of religious commitment might seem a little ridiculous or embarrassing or flippant. But as I promised, Ill play it now myself.

What Im looking for when I gamble on a world-picture is something that makes sense of the four major features of existence that give rise to religious questions the striking fact of cosmic order, our distinctive consciousness, our strong moral sense and thirst for justice and the persistent varieties of supernatural experience. The various forms of materialism strike me as very weak on all four counts, and the odds that what Thomas Nagel called the materialist neo-Darwinian conception of nature is true therefore seem quite low. All these numbers will be a little arbitrary, but for the sake of the game Ill set the probability that a hard materialism accurately describes reality at 2 percent (and I think Im being generous there).

So what does? Well, if you decide treat every religious revelation as essentially equally plausible or implausible and decline to choose between them, the best world-picture candidates are either a form of classical theism as it would have been understood by most pre-modern thinkers and continues to be understood by many theologians today (again, read David Bentley Hart for a recent and compelling case), or else a form of pantheism or panentheism or panpsychism in which God/consciousness/the universe are in some sense overlapping categories, and all spiritual/supernatural experiences are partial and personal and culturally mediated glimpses of a unity.

Both of these possibilities seem to have more explanatory power across my four categories than does, say, a hard deism (which makes the varieties of religious experience a lot harder to explain) or a dualism or a gnosticism (both of which seem a little unparsimonious, and also somewhat poor fits for the data of religious experience) or a literalist polytheism (which begs too many questions about cosmic order, which is why philosophically-serious polytheists often tend to be pantheists or classical theists at bottom). And the latter possibility, some sort of pantheism, seems to be where a lot of post-Christians who are too sensible or too experienced to accept a stringent atheism are drifting it shows up in different forms in writers like Barbara Ehrenreich, Sam Harris, Thomas Nagel, Anthony Kronman, even Philip Pullman, and it pervades a great deal of pop spirituality these days. Indeed it might be where I would end up if I radically changed my mind about the credibility of the Christian story; Im not entirely sure. (It would probably come down to questions of theodicy; Ill spare you the provisional thought process.)

For now, Ill give odds as follows (again, treating all revelations equally): Classical theism 45 percent, the pantheistic big tent 40 percent, gnosticism 6 percent, hard no supernatural deism 4 percent, dualism 3 percent. Which still leaves that 2 percent chance that Daniel Dennett has it right.

I told you this would seem a bit silly (and I know Im leaving out various combinations and permutations, sorry, maybe someday Ill tackle process theology but not today). But pressing on, I dont actually think you can treat all revelations equally, because theyre all so strikingly different and theres no good reason to treat them interchangeably. Instead, I think what youre looking for is a kind of black swan among revelations, a tradition that seems particularly plausible in the historical grounding of its claims and whose theological implications fit in well with the combination I proposed to you earlier, the mix of the comprehensible and the unfathomable that would do justice both to a divine Otherness and a divine desire to be known by us, the most godlike (and devil-like) beings in the created universe so far as we can tell.

And, no surprise here, I think the combination of the Hebrew Bible and the New Testament is the darkest swan in the sea of religious stories the compendium of stories, histories, poems and prophecies and parables and (yes) eyewitness accounts that most suggests an actual unfolding divine revelation, and whose unlikely but overwhelming role as a history-shaping force endures even in what is supposed to be our oh-so-disenchanted world. As a wise man once remarked (it was you), the Bible as a whole is one of the most beautiful, strange, and open-to-multiple-interpretation books that there is, and its emergence from a minor but oddly-resilient nation of Semites is both more strikingly unlikely and less contingent on a single religious personality than the genesis of any other holy book and thats even before you dig into what Christians consider its culminating revelation, a miraculous story that unfolds not in myth or prehistory but at an apex of earthly civilization, in the harsh light of recorded history, with multiple overlapping testimonies to its reality that two thousand years of criticism have not even begun to convincingly discredit.

Reasonable people can disagree with this take, but thats mine. Im betting on the Judeo-Christian story as an extended revelation unlike any other on the theology that the early Christians came up with to explain what happened in their midst, which balances the reasonable with the paradoxical in ways that fit the ordered strangeness of reality itself on Christianitys subsequent world-altering influence as a fulfillment of the brazenly implausible predictions that both Israels prophets and the gospel writers made about just how far Yahwehs rule could spread and finally on the mix of consistency and resilience, revival and reinvention in the central strand of Christianity across two millennia, which is why I make my home in the Roman Catholic Church.

You want those embarrassingly crude numbers on all this? Fine. Lets give Western monotheism a 60 percent chance of containing the most important and dispositive revelation. Then within Western monotheism, Judaism alone seems to me much less likely than does Christianity and Judaism together, so Id put Judaism-as-primary-revelation at 20 percent, Christianity as the fulfillment of Judaism at 65 percent, some Jewish-Christian-Islamic synthesis that weve failed to grasp at 10 percent, and Muhammed as the seal of the prophets at 5 percent. Then within Christianity itself, lets give it a 50 percent chance that Roman Catholicism is the truest church (pending Francis-era developments, as I said), a 20 percent chance that Catholicism and Orthodoxy have an equal claim, a 5 percent chance thats its Orthodoxy alone, a 10 percent chance for the Anabaptists, a 5 percent chance for the Calvinists, and 10 percent that the church is simply too broken for any specific body to have exclusive claims, in which case nondenominationals and big-tent Anglicans probably have the right approach.

There: Ive probably blasphemed, weakened my Catholic credentials, endangered my soul, insulted my religious brethren, picked pointless fights with Muslims and Calvinists, and betrayed a juvenile understanding of statistics.

So the least you can do, Tyler, after all of this, is to spend a few more Sundays in your local church.

See the article here:
Should Tyler Cowen Believe in God? - New York Times (blog)

‘Biggest game ever’ for Lions as immortality beckons – Irish Times

New Zealand v British & Irish Lions

Venue: Eden Park.

Kick-off: 7.35pm NZ time/8.35am Irish/UK time.

On TV: Live on Sky Sports

The Lions embarked upon a tour described as suicidal by Graham Henry and both they and their head coach were derided after a scratchy opening win over the Barbarians and a loss to the Blues, and at various points along the way. Come the final Saturday, they stand on the cusp of immortality.

Its been quite the journey; a rollercoaster ride up and down the Land of the Long White Cloud which scaled epic heights in Wellington last Saturday when they became the first side to beat the All Blacks in New Zealand in eight years.

For the momentous climax came the hardest part of all, ending the All Blacks 37-match winning run at Eden Park since France won 23-20 in 1994.

Sen OBrien has played 49 Tests for Ireland and four for the Lions. Hes been part of a Lions Test series win, been in an Irish Six Nations-winning team and three European Cup-winning squads with Leinster. So how does this rate?

The biggest, he says with a steely-eyed intent. This is the biggest game Ive ever been involved in, I think, this weekend.

The former All Blacks winger and Italian and Blues head coach, John Kirwan, said earlier this week that regardless of the third Test result, Warren Gatlands legacy is secure, and theres even been grudging respect from the New Zealand Herald.

Yet the portrayal of him as a clown amid an almost daily demonisation of him will not be easily forgotten. One of his assistants with Wales and here, Rob Howley, said: The way Warren Gatlands been treated, its been a disgrace, hasnt it? Its an absolute disgrace. We all love sport and rugby and you can be critical of technical or tactical elements of the Lions or New Zealand, but when that becomes personal criticism I think we all step over the mark and thats happened over the last four weeks of the tour.

Hes a Kiwi. You have to applaud what Warren Gatlands achieved as a Kiwi in the northern hemisphere and Ive no doubt what hell achieve when he comes back to New Zealand as well. Hes probably one of the best coaches in world rugby at this moment in time.

Asked if he envisaged Gatland being All Blacks coach one day, Howley said: Yeah, I got no doubt he will be. Citing Gatlands success with Connacht, Ireland and Wales, not to mention Wasps, where Howley played, he added: I learned more as a player when I was coached by Warren Gatland at the age of 31 than I had by any other coaches. And Ive been very fortunate to be coached by a lot of coaches.

He understands the games, he understands players, and I think thats the biggest asset that hes got, said Howley, which was perhaps a legacy of his time as understudy to Sean Fitzpatrick.

All the while, Howley said, Gatland remained calm and relaxed in steering the Lions through a relentless schedule. At the start of the tour you were going at 25mph and now were going at 18mph, said Howley.

Having their key decision-makers, Owen Farrell, Johnny Sexton and Dan Biggar all available for the pre-tour camp in the Carton House was key.

The emergence of the Sexton-Farrell axis may have contributed to the All Blacks recalling Julian Savea, and an indication that they would defend pretty flat.

I think they will revert to the kicking game, he added, and theyll come off 9. Its about making sure that our systems in place that were good last week are better than they were the week before.

If we can do that, its making sure that when weve got the ball, we take our opportunities. Its one game, as a coach and a player that you are going to be so excited because it is the ultimate challenge of creating history. Thats what weve got to look forward to.

New Zealand: Jordan Barrett (Hurricanes); Israel Dagg (Crusaders), Anton Lienert-Brown (Chiefs), Ngane Laumape (Hurricanes), Julien Savea (Hurricanes); Beauden Barrett (Hurricanes), Aaron Smith (Highlanders); Joe Moody (Crusaders), Codie Taylor (Crusaders), Owen Franks (Crusaders), Brodie Retallick (Chiefs) Samuel Whitelock (Crusaders), Jerome Kaino (Blues), Sam Cane (Chiefs), Kieran Read (Crusaders, captain).

Replacements: Nathan Harris (Chiefs), Wyatt Crockett (Crusaders),

Charlie Faumuina (Blues), Scott Barrett (Crusaders), Ardie Savea (Hurricanes), TJ Perenara (Hurricanes), Aaron Cruden (Chiefs) or Lima Sopoaga (Highalnders), Malakai Fekitoa (Highlanders).

British & Irish Lions: Liam Williams (Scarlets, Wales); Anthony Watson (Bath Rugby, England), Jonathan Davies (Scarlets, Wales), Owen Farrell (Saracens, England), Elliot Daly (Wasps, England); Johnny Sexton (Leinster, Ireland), Conor Murray (Munster, Ireland); Mako Vunipola (Saracens, England,) Jamie George (Saracens, England), Tadhg Furlong (Leinster, Ireland), Maro Itoje (Saracens, England), Alun Wyn Jones (Ospreys, Wales), Sam Warburton (Cardiff Blues, Wales, capt), Sean OBrien (Leinster, Ireland), Taulupe Faletau (Bath Rugby, Wales).

Replacements: Ken Owens (Scarlets, Wales), Jack McGrath (Leinster, Ireland), Kyle Sinckler (Harlequins, England), Courtney Lawes (Northampton, England), CJ Stander (Munster, Ireland), Rhys Webb (Ospreys, Wales), Ben Teo (Worcester Warriors, England), Jack Nowell (Exeter, England).

Referee: Romain Poite (France).

Previous meetings: Played 40, New Zealand 30 wins, 3 draws, Lions 7 wins.

Betting (Paddy Powers): 2/7 New Zealand, 22/1 Draw, 7/2 Lions. Handicap betting (Lions +11 pts) Evens New Zealand, 19/1 Draw, Evens Lions.

Forecast: The Lions to win.

View original post here:
'Biggest game ever' for Lions as immortality beckons - Irish Times

UK’s chief medical officer calls for gene testing revolution in cancer treatment – Daily Nation

Saturday July 8 2017

Kenyans mark World Cancer Day on February 4, 2016 in Eldoret town. Tiny errors in DNA code can lead to cancer and other illnesses. PHOTO | JARED NYATAYA | NATION MEDIA GROUP

A revolution in the search for cancer treatments has been proposed by Englands chief medical officer.

Prof Sally Davies wants gene-testing to be introduced on a routine basis.

I want the National Health Service to be offering genomic medicine, that means diagnosis of our genes, to patients where they can possibly benefit, she said.

GENETIC TESTS Testing, she said, should be standard across cancer care as well as some other areas of medicine, including rare diseases and infections.

Doctors are already using genetic tests to identify and better treat different strains of the infectious disease, tuberculosis.

Humans have about 20,000 genes, bits of DNA code or instructions that control how our bodies work.

Tiny errors in this code can lead to cancer and other illnesses.

Gene-screening can reveal these errors by comparing tumour and normal DNA samples from the patient.

Professor Davies says in about two-thirds of cases, this information can improve their diagnosis and care.

Doctors can tailor treatments to the individual, picking the drugs most likely to be effective.

Currently, genetic testing in England is done at 25 regional laboratories, as well as some other small centres.

Professor Davies wants to centralise the service and set up a national network to ensure equal access to the testing across the country.

She said one hurdle could be doctors themselves, who dont like change.

Patients should persuade them to move from a local to a national service. *** Joe Furness was in Newcastle upon Tyne when he was invited to a party in London.

A three-hour, one-way train trip would cost him 78.50 (Sh10,517) and a plane flight 106, but Joe, aged 21, is a poor student and didnt have much money.

What he did have however was time. So Joe decided to take a detour via Spain.

CAR HIRE Flying from Newcastle to the Spanish island of Menorca cost him 16.00.

There he hired a car for 7.50 and spent the night in it, while sipping a 4.50 cocktail.

Next morning he flew to London for 11.00, joined the party, then grabbed a lift home with a pal afterwards.

Total cost of 39 was a saving of 39.50 on a train journey from Newcastle and 67 on a flight.

Distance travelled was 2,350 miles, against 290 miles from the North to London. *** Bradley Lowery is a six-year-old boy who won the hearts of the nation by campaigning for his beloved Sunderland Football Club and for its top scorer, Jermaine Defoe.

TV film of Defoe holding a smiling Bradley in his arms before a recent game appeared on nationwide television.

What everyone knows, of course, is that Bradley is dying from the childhood cancer neuroblastoma.

A fund-raising campaign raised money for him and will be used for other sick children when Bradley dies.

Now it seems fraudsters have been setting up pages on the internet claiming to be collecting for the boys cause.

His family have warned against them. Please be vigilant, they said in a message on Facebook.

You have to wonder, how low can some people stoop?

*** Some 400 plastic bottles are sold per second in this country and millions end up, along with other garbage, in the worlds oceans.

In fact, scientists calculate that by 2050, the oceans will contain more plastic by weight than fish.

The opposition Labour party is pressing for the introduction of a money-back return scheme, which has been introduced in many other countries and has proved successful in reducing the scale of littering.

You pay a bit extra for your drink but you get it back if you return the bottle, which the drinks company then recycles.

Coca-Cola, among others, is backing the idea. *** Famous one-liners:

Doctors recommend eight glasses of water per day. Why does this seem impossible when eight glasses of beer is so easy? Anonymous.

If you want to know what God thinks of money, look at the people he gave it to. American writer Dorothy Parker.

The two most beautiful words in the English language are Cheque enclosed. Dorothy Parker.

PLAGIARISM I asked God for a bike but I know He doesnt work that way, so I stole a bike and asked for forgiveness. Internet.

I wouldnt say I was the best football manager in the business, but I was in the top one. Brian Clough, British football manager.

To steal ideas from one person is plagiarism; to steal from many is research. Anonymous

England and America are two countries separated by a common language. Irish writer George Bernard Shaw.

If I agreed with you, then we would both be wrong. Internet.

Interior Cabinet Secretary collapsed in his house and was rushed to hospital by family and

He is becoming the Presidents go-to-guy when things need to be fixed.

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UK's chief medical officer calls for gene testing revolution in cancer treatment - Daily Nation

Debate Rages Over Safety Of CRISPR Gene-Editing Technique … – IFLScience

In the last few years, CRISPR the precise and easily available gene-editing technique has gone from strength to strength. Right now, its more potential than practical, but its uses are almost countless. From removing genetic diseases from babies before they are born to causing cancerous cells to self-destruct, its more likely than not it will rapidly become a key tenet of modern medicine.

The technique is being used in a massive number of trials right now, and a few of them have highlighted that its far from fully understood and far from being perfected. One particularly controversial study released back in May claimed that CRISPR was in fact dangerous, but now another study, currently sitting on the bioRxiv pre-print server, has dismissed this research as flawed.

The original study looked at the effect of using CRISPR in mice, and found that it introduced a large number of previously unknown mutations into their genome. The mice were blind, and the gene-editing technique was used to effectively cure them of this affliction.

While it was successful, it also appeared to inadvertently lead to mutations elsewhere at least 1,500 of them, in fact. Of these, just over 100 mutations were more serious, involving not just DNA base pair changes, but full deletions or insertions of new segments of DNA.

What is CRISPR? Wired via YouTube

Although there were no physiological side effects, unwanted mutations are always a cause for concern. As a result, the authors concluded that CRISPR has the potential to be quite hazardous to the normal operation of biological systems.

When this study was released, it caused quite a stir. Similar studies had only shown a handful of changes, which turned out to be harmless. People were quick to point out that the study was very small, involving just three mice, and that the changes made elsewhere on their genomes could easily be attributed to normal genetic mutations that take place all the time.

Now, a Harvard University-led team have suggested that these unwanted mutations have a far more innocuous explanation.

Apart from the fact that there is no direct line of evidence demonstrating that CRISPR caused the mutations, the team note that the mice used in the study were very closely related. This means that whatever mutations one had, the other would have had too.

Combined with the fact that the mutations were found nowhere near the actual gene-editing site, the authors conclude that, once again, CRISPR is probably safe after all. Plenty more trials are needed to verify this, of course but the point here is that this study raised a massive red flag when it wasnt justified in doing so.

[H/T: New Scientist]

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Debate Rages Over Safety Of CRISPR Gene-Editing Technique ... - IFLScience

In northern humans, evolution favored shorter bones but with a painful trade-off – Stanford Medical Center Report

Many people think of osteoarthritis as a kind of wear-and-tear disease, but theres clearly a genetic component at work here as well.

The researchers were studying a gene called GDF5 that Kingsleys laboratory first linked to skeletal growth in the early 1990s. GDF5 is involved in bone growth and joint formation, and mutations in the coding portion of the gene have been shown to cause malformations in leg-bone structure in mice. In humans, GDF5 mutations are associated with shorter stature and joint problems; in particular, two nucleotide changes immediately upstream of the gene have been strongly associated with a 1.2- to 1.8-fold increase in the risk of osteoarthritis.

In the new study, the researchers were interested in learning more about how the DNA sequences surrounding GDF5 might affect the genes expression. Often, these noncoding sequences contain key regulatory regions known as promoters and enhancers. Capellini, Chen and Cao were able to identify a previously unknown enhancer region they termed GROW1, which is several thousand nucleotides downstream of GDF5.

When the researchers analyzed the sequence of GROW1 in the 1,000 Genomes Project database, which collects and compares sequences from many human populations around the globe, they identified a single nucleotide change that is highly prevalent in Europeans and Asians but that rarely occurs in Africans. When they introduced this nucleotide change into laboratory mice, they found that it decreased the activity of GDF5 in the growth plates of the long bones of fetal mice.

Further research showed that this nucleotide change has been repeatedly favored during human evolution. Modern humans migrated from Africa between 50,000 and 100,000 years ago. But they werent the first to leave the continent. Neanderthals and Denisovans moved north into Europe and Asia about 600,000 years ago. Interestingly, the researchers found that the same GROW1 variant was found in the DNA of both ancient and modern humans in Europe and Asia.

However, theres a dark side to this stocky, hardy body type: The GDF5 variant that reduces bone length comes hand-in-hand with the two upstream nucleotide changes known to confer an increased risk for osteoarthritis.

Its clear that the genetic machinery around a gene can have a dramatic impact on how it works, said Capellini. The variant that decreases height is lowering the activity ofGDF5in the growth plates of the bone. Interestingly, the region that harbors this variant is closely linked to other mutations that affect GDF5 activity in the joints, increasing the risk of osteoarthritis in the knee and hip.

The potential medical impact of the finding is very interesting because so many people are affected, said Kingsley. This is an incredibly prevalent, and ancient, variant. Many people think of osteoarthritis as a kind of wear-and-tear disease, but theres clearly a genetic component at work here as well. Now weve shown that positive evolutionary selection has given rise to one of the most common height variants and arthritis risk factors known in human populations.

A researcher from the University of Waterloo in Ontario, Canada, also contributed to the study.

The research was supported by the National Sciences and Engineering Research Council of Canada, the Arthritis Foundation, the National Institutes of Health (grant AR42236), the Howard Hughes Medical Institute, the Milton Fund of Harvard, the China Scholarship Council and the Jason S. Bailey Fund of Harvard.

Stanfords Department of Developmental Biology also supported the work.

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In northern humans, evolution favored shorter bones but with a painful trade-off - Stanford Medical Center Report

Lab reports: eligibility criteria sparks row – The Hindu

Lab reports: eligibility criteria sparks row
The Hindu
In 2005, members of an ad hoc committee appointed by the Supreme Court and of the executive committee of the MCI had approved the decision of the ethics committee that a person with M.Sc. (Medical Biochemistry) degree with or without Ph.D is entitled ...

and more »

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Lab reports: eligibility criteria sparks row - The Hindu

Global Biomarkers Technologies, Markets and Companies Projections Report 2017 – PR Newswire (press release)

This report describes different types of biomarkers and their discovery using various -omics technologies such as proteomics and metabolomics. Molecular diagnostics technologies are used for the discovery of biomarkers and new tests are also based on biomarker.

This report follows the broad definition of a biomarker as a characteristic that can be objectively measured and evaluated as an indicator of normal biological or pathogenic processes as well as pharmacological responses to a therapeutic intervention. Tests based on biomarkers have been around for more than half a century, but interest in their application for diagnostics and drug discovery as well as development has increased remarkably since the beginning of the 21st century.

Currently the most important applications of biomarkers are in drug discovery and development. The role of biomarkers in various therapeutic areas particularly cancer, cardiovascular diseases and disorders of the central nervous system, is described. Biomarkers are useful not only for diagnosis of some of these diseases but also for understanding the pathomechanism as well as a basis for development of therapeutics.

Biomarkers will facilitate the combination of therapeutics with diagnostics and will thus play an important role in the development of personalized medicine. Biomarkers play a role in use of pharmacogenetics, pharmacogenomics and pharmacoproteomics for development of personalized medicine.

Many of the regulatory issues concerning biomarkers are related to genomics, proteomics, molecular diagnostics and pharmacogenomics/pharmacogenetics. Validation of biomarkers and their role in clinical trials is discussed.

Biomarker markets are estimated from 2016 to 2026 according to share of markets for various technologies and applications: proteomics, metabolomics, molecular diagnostics, drug discovery, clinical trials, and bioinformatics. Market values are further split according to therapeutic applications and major geographical areas. Unfulfilled needs in biomarkers are identified as well as the drivers for biomarker markets. Challenges facing the biomarker industry and strategies for developing biomarker markets are discussed.

A large number of companies with varying technical backgrounds are involved in biomarkers and 304 of these are profiled in part 2 of the report with classification into various categories.These also include major pharmaceutical companies. There is tabulation of 467 collaborations between companies and additional academic collaborations are mentioned in the individual profiles of companies. The report is supplemented by 1,200 references, 77 tables and 20 figures

Key Topics Covered:

Part 1: Technologies & Markets

Executive Summary

1. Introduction

2. Technologies for Discovery of Biomarkers

3. Biomarkers and Molecular Diagnostics

4. Biomarkers for Drug Discovery & Development

5. Role of Biomarkers in Healthcare

6. Biomarkers of Cancer

7. Biomarkers of Disorders of the Nervous System

8. Biomarkers of Cardiovascular Disorders

9. Biomarkers & Personalized Medicine

10. Biomarkers and Regulatory issues

11. Markets for Biomarkers

12. References

Part II: Companies

13. Companies

For more information about this report visit https://www.researchandmarkets.com/research/4nrrhw/biomarkers

Source: Jain PharmaBiotech

Media Contact:

Research and Markets Laura Wood, Senior Manager press@researchandmarkets.com

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Global Biomarkers Technologies, Markets and Companies Projections Report 2017 - PR Newswire (press release)

Broccoli Battles Diabetes – Anti Aging News

3864 2 Posted on Jul 03, 2017, 6 a.m.

New research shows that sulforaphane, an antioxidant found in broccoli, may slow or even reverse type 2 diabetes.

A compound found in broccoli may slow or even reverse the progression of type 2 diabetes in overweight people. The study was published in the June 2017 issue of the Science Translational Medicine journal. The study was led by assistant professor Anders Rosengren and doctoral student Annika Axelsson, both from the University of Gothenburg in Sweden.

Multi-Method Study

Researchers used laboratory experiments using animals, computational methods, and clinical trials with human subjects to complete their study.

During the laboratory portion of the study, the researchers analyzed liver tissue from diabetic mice. The mice were raised on a Western-style diet with a 42% fat and .15% cholesterol content. From the analysis, the team was able to identify 1,720 different genes that affected hyperglycemia. Hyperglycemia is a condition characterized by high blood sugar levels. Further analysis allowed the researchers to narrow their focus on a set of 50 genes that linked together to raise blood sugar levels to form the type II diabetes disease signature.

The second phase of the study involved using a mathematical modeling program to rank known compounds for their ability to reverse the disease signature by reducing the genes ability to express themselves. Sulforaphane, a chemical compound found in cruciferous vegetables like Brussel sprouts and broccoli, ranked highest. The substance was able to successfully reduce glucose production in lab-grown cell groups. Tests were then completed using laboratory rodents. Despite being fed a high-fat, high-fructose diet, the rats who were given doses of Sulforaphane showed a marked improvement in glucose tolerance.

After the successful animal trials, researchers tested 97 human patients with type 2 diabetes. Participants took a daily dose of Sulforaphane, in the form of a powdered, concentrated broccoli sprout extract, for 12 weeks. Patients with normal weight were not affected by the compound. Obese participants saw a 10% decrease in fasting blood sugar by the end of the trial. That means patients were able to significantly reduce the risk of developing diabetes-related health complications without causing gastrointestinal problems or other side effects.

Possible Replacement for Metformin

Lifestyle changes, such as eating healthy, exercising regularly, and maintaining a healthy weight, are the primary treatments for diabetes. However, many patients need the help of drug therapies to stabilize their blood sugar and insulin levels. Currently, the best treatment for type 2 diabetes is metformin. However, many overweight diabetes patients are unable to take this medication. Roughly 15% of those with diabetes also have reduced kidney function. Taking metformin could cause their bodies to retain lactic acid. This leads to lactic acidosis, a condition in that causes nausea, abdominal pain, shallow breathing, muscle pain and cramps, and fatigue. For those who are unable to take the standard treatment, Sulforaphane may be a viable alternative.

Researchers are currently developing a clinical study involving participants with prediabetes. They hope to use Sulforaphane to prevent these patients from developing type 2 diabetes.

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Broccoli Battles Diabetes - Anti Aging News

Experts Sound the Alarm as Drug Resistant Gonorrhea Goes Global – Gizmodo

Neisseria gonorrhoeae, the bacteria responsible for gonorrhea. (Image: National Institute of Biomedical Imaging and Bioengineering)

Describing it as a serious situation, the World Health Organization has issued a grim warning about the dramatic rise of antibiotic resistant gonorrhea around the world. The agency is now calling for the quick development of drugs to treat the sexually transmitted disease.

Data collected from nearly 80 countries shows that antibiotic resistance is making gonorrhea much tougher, and at times impossible, to treat. The disease is becoming increasingly immune to older and cheaper antibiotics, and treatment-resistant strains are now appearing even in countries where monitoring practices are top notch. WHO, with help from a global team of researchers, is set to release these findings in a special edition of PLoS Medicine prior to the STI & HIV World Congress that will be held in Rio from July 9-12.

The bacteria that cause gonorrhea are particularly smart, said WHO medical officer Teodora Wi in a statement. Every time we use a new class of antibiotics to treat the infection, the bacteria evolve to resist them.

Each year, the sexually transmitted disease afflicts an estimated 78 million people worldwide. Gonorrhea is caused by the Neisseria gonorrhoeae bacterium, and it infects both men and women. Symptoms include a greenish yellow or whitish discharge from the penis and vagina, burning while urinating, swollen glands in the throat (due to oral sex), and other unpleasant manifestations. The disease is particularly tough on women, and its frequently accompanied by pelvic inflammatory disease, infertility, ectopic pregnancy (when the fetus develops outside the uterus), and an increased risk of contracting HIV. WHO says the disease is spreading on account of decreased condom use, increased urbanization and travel, poor detection measures, and inadequate or failed treatments.

Data collected by WHO from 2009 to 2014 shows widespread resistance to the commonly used antibiotics ciprofloxacin and azithromycin, along with emerging resistance to the current last-resort treatment involving injectable ceftriaxone. Superbugs that couldnt be treated with the last line of defence have been reported in France, Japan, and Spain. The agency is now advising doctors to prescribe a double-whammy treatment involving both azithromycin and ceftriaxone. This is a rather grim prescription, given that azithromycin-resistant gonorrhea is now being reported in 81 percent of countries, and ceftriaxone-resistant gonorrhea has taken root in 66 percent of countries. Ultimately, WHO says we need to develop a vaccine, because gonorrhea will always remain a step ahead of our efforts to curb it with antibiotics.

WHO is also calling for the rapid development of new drugs to treat the disease. Disturbingly, the research and development pipeline for gonorrhea is relatively empty, with only three new candidate drugs currently in clinical development, according to WHO. Part of the problem has to do with Big Pharmas reluctance to develop drugs that treat gonorrhea, which are only taken for short periods of time (unlike meds for chronic diseases), and become less effective over time as resistance develops.

To address the pressing need for new treatments for gonorrhea, we urgently need to seize the opportunities we have with existing drugs and candidates in the pipeline, said Manica Balasegaram, who directs the not-for-profit Global Antibiotic Research and Development Partnership (GARDP). In the short term, we aim to accelerate the development and introduction of at least one of these pipeline drugs, and will evaluate the possible development of combination treatments for public health use. Any new treatment developed should be accessible to everyone who needs it, while ensuring its used appropriately, so that drug resistance is slowed as much as possible.

In addition to developing new drugs and re-evaluating existing antibiotics, WHO says its critical to develop treatments that are easier to administer, and produce more simplified treatment guidelines.

An 18-month review into antimicrobial resistance warns that superbugs will kill upwards of 10

This latest development is another discouraging reminder that our antibiotics are failing. Last year, the Institute and Faculty of Actuaries in Britain claimed that a new era of antimicrobial resistance is already upon us, and that 50,000 people are already dying each year in the US and Europe from untreatable infections. Should nothing be done to offset this trend, as many as 10 million people could die each year by the mid-point of the 21st century, making antimicrobial resistance more deadly than cancer.

Antibiotics that treat gonorrhea may be failing, but theres still a way to fight back: practice safe sex.

[World Health Organization, CBC News]

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Experts Sound the Alarm as Drug Resistant Gonorrhea Goes Global - Gizmodo

Healthcare Nanotechnology (Nanomedicine) Market Expected to Generate Huge Profits by 2015 2021: Persistence … – MilTech

Nanotechnology is one of the most promising technologies in 21st century. Nanotechnology is a term used when technological developments occur at 0.1 to 100 nm scale. Nano medicine is a branch of nanotechnology which involves medicine development at molecular scale for diagnosis, prevention, treatment of diseases and even regeneration of tissues and organs. Thus it helps to preserve and improve human health. Nanomedicine offers an impressive solution for various life threatening diseases such as cancer, Parkinson, Alzheimer, diabetes, orthopedic problems, diseases related to blood, lungs, neurological, and cardiovascular system.

Development of a new nenomedicine takes several years which are based on various technologies such as dendrimers, micelles, nanocrystals, fullerenes, virosome nanoparticles, nanopores, liposomes, nanorods, nanoemulsions, quantum dots, and nanorobots.

In the field of diagnosis, nanotechnology based methods are more precise, reliable and require minimum amount of biological sample which avoid considerable reduction in consumption of reagents and disposables. Apart from diagnosis, nanotechnology is more widely used in drug delivery purpose due to nanoscale particles with larger surface to volume ratio than micro and macro size particle responsible for higher drug loading. Nano size products allow to enter into body cavities for diagnosis or treatment with minimum invasiveness and increased bioavailability. This will not only improve the efficacy of treatment and diagnosis, but also reduces the side effects of drugs in case of targeted therapy.

Global nanomedicine market is majorly segmented on the basis of applications in medicines, targeted disease and geography. Applications segment includes drug delivery (carrier), drugs, biomaterials, active implant, in-vitro diagnostic, and in-vivo imaging. Global nanomedicine divided on the basis of targeted diseases or disorders in following segment: neurology, cardiovascular, oncology, anti-inflammatory, anti-infective and others. Geographically, nanomedicine market is classified into North America, Europe, Asia Pacific, Latin America, and MEA. Considering nanomedicine market by application, drug delivery contribute higher followed by in-vitro diagnostics. Global nanomedicine market was dominated by oncology segment in 2012 due to ability of nanomedicine to cross body barriers and targeted to tumors specifically however cardiovascular nanomedicine market is fastest growing segment. Geographically, North America dominated the market in 2013 and is expected to maintain its position in the near future. Asia Pacific market is anticipated to grow at faster rate due to rapid increase in geriatric population and rising awareness regarding health care. Europe is expected to grow at faster rate than North America due to extensive product pipeline portfolio and constantly improving regulatory framework.

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Major drivers for nanomedicine market include improved regulatory framework, increasing technological know-how and research funding, rising government support and continuous increase in the prevalence of chronic diseases such as obesity, diabetes, cancer, kidney disorder, and orthopedic diseases. Some other driving factors include rising number of geriatric population, awareness of nanomedicine application and presence of high unmet medical needs. Growing demand of nanomedicines from the end users is expected to drive the market in the forecast period. However, market entry of new companies is expected to bridge the gap between supply and demand of nanomedicines. Above mentioned drivers currently outweigh the risk associated with nanomedicines such as toxicity and high cost. At present, cancer is one of the major targeted areas in which nanomedicines have made contribution. Doxil, Depocyt, Abraxane, Oncospar, and Neulasta are some of the examples of pharmaceuticals formulated using nanotechnology.

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Key players in the global nanomedicine market include: Abbott Laboratories, CombiMatrix Corporation, GE Healthcare, Sigma-Tau Pharmaceuticals, Inc., Johnson & Johnson, Mallinckrodt plc, Merck & Company, Inc., Nanosphere, Inc., Pfizer, Inc., Celgene Corporation, Teva Pharmaceutical Industries Ltd., and UCB (Union chimique belge) S.A.

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Healthcare Nanotechnology (Nanomedicine) Market Expected to Generate Huge Profits by 2015 2021: Persistence ... - MilTech