Global Nanomedicine Industry 2017 Market Growth, Trends and Demands Research Report – MENAFN.COM

(MENAFN Editorial) iCrowdNewswire - Sep 4, 2017

The Global Nanomedicine Market 2017 Industry Research Report' report provides a basic overview of the industry including its definition, applications and manufacturing technology. Then, the report explores the Global major industry players in detail.

The Global Nanomedicine Market Research Report 2017 renders deep perception of the key regional market status of the Nanomedicine Industry on a global level that primarily aims the core regions which comprises of continents like Europe, North America, and Asia and the key countries such as United States, Germany, #China and Japan.

Complete report on Nanomedicine market report spread across 116 pages, profiling 12 companies and supported with tables and figuresavailable @

The report on 'Global Nanomedicine Market is a professional report which provides thorough knowledge along with complete information pertaining to the Nanomedicine industry propos classifications, definitions, applications, industry chain summary, industry policies in addition to plans, product specifications, manufacturing processes, cost structures, etc.

The potential of this industry segment has been rigorously investigated in conjunction with primary market challenges. The present market condition and future prospects of the segment has also been examined. Moreover, key strategies in the market that includes product developments, partnerships, mergers and acquisitions, etc., are discussed. Besides, upstream raw materials and equipment and downstream demand analysis is also conducted.

Report Includes:-

The report cloaks the market analysis and projection of 'Nanomedicine Market on a regional as well as global level. The report constitutes qualitative and quantitative valuation by industry analysts, first-hand data, assistance from industry experts along with their most recent verbatim and each industry manufacturers via the market value chain. The research experts have additionally assessed the in general sales and revenue generation of this particular market. In addition, this report also delivers widespread analysis of root market trends, several governing elements and macro-economic indicators, coupled with market improvements as per every segment.

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Global Nanomedicine market competition by top manufacturers/players, with Nanomedicine sales volume, Price (USD/MT), revenue (Million USD) and market share for each manufacturer/player; the top players including: GE Healthcare, Johnson & Johnson, Mallinckrodt plc, Merck & Co. Inc., Nanosphere Inc., Pfizer Inc., SigmaTau Pharmaceuticals Inc., Smith & Nephew PLC, Stryker Corp, Teva Pharmaceutical Industries Ltd., UCB (Union chimique belge) S.A

The report is generically segmented into six parts and every part aims on the overview of the Nanomedicine industry, present condition of the market, feasibleness of the investment along with several strategies and policies. Apart from the definition and classification, the report also discusses the analysis of import and export and describes a comparison of the market that is focused on the trends and development. Along with entire framework in addition to in-depth details, one can prepare and stay ahead of the competitors across the targeted locations. The fact that this market report renders details about the major market players along with their product development and current trends proves to be very beneficial for fresh entrants to comprehend and recognize the industry in an improved manner. The report also enlightens the productions, sales, supply, market condition, demand, growth, and forecast of the Nanomedicine industry in the global markets.

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Every region's market has been studied thoroughly in this report which deals with the precise information pertaining to the Marketing Channels and novel project investments so that the new entrants as well as the established market players conduct intricate research of trends and analysis in these regional markets. Acknowledging the status of the environment and products' up gradation, the market report foretells each and every detail.So as to fabricate this report, complete key details, strategies and variables are examined so that entire useful information is amalgamated together for the understanding and studying the key facts pertaining the global Nanomedicine Industry. The production value and market share in conjunction with the SWOT analysis everything is integrated in this report.

Table of Contents

1 Nanomedicine Market Overview 2 Global Nanomedicine Market Competition by Manufacturers 3 Global Nanomedicine Capacity, Production, Revenue (Value) by Region (2011-2016) 4 Global Nanomedicine Supply (Production), Consumption, Export, Import by Regions (2011-2016) 5 Global Nanomedicine Production, Revenue (Value), Price Trend by Type 6 Global Nanomedicine Market Analysis by Application 7 Global Nanomedicine Manufacturers Profiles/Analysis

8 Nanomedicine Manufacturing Cost Analysis 9 Industrial Chain, Sourcing Strategy and Downstream Buyers 10 Marketing Strategy Analysis, Distributors/Traders 11 Market Effect Factors Analysis 12 Global Nanomedicine Market Forecast (2016-2021) 13 Research Findings and Conclusion

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HudsonAlpha Institute for Biotechnology

President and Scientific Director, Ontario Institute for Cancer Research and Director, P3G (Public Population Project in Genomics)President and Scientific Director, Ontario Institute for Cancer Research Scientific Director, P3GDr. Thomas J. Hudson is president and scientific director of the Ontario Institute for Cancer Research. He is implementing the institutes strategic plan, working with cancer research institutions across Ontario to leverage existing strengths. The plan focuses on prevention, early diagnosis, cancer targets and new therapeutics. Its innovation platforms include imaging and interventions, bio-repositories and pathology, genomics and high-throughput screening, and informatics and biocomputing. Dr. Hudson is recruiting more than 50 internationally recognized principal investigators.Dr. Hudson was the founder and Director of the McGill University and Genome Quebec Innovation Centre and Assistant-Director of the Whitehead/MIT Center for Genome Research. Dr. Hudson is internationally renowned for his work in genomics. At the Whitehead Institute, Dr. Hudson led the effort to generate dense physical and gene maps of the human and mouse genomes. He is a leader in the development and applications of robotic systems and DNA-chip based methodologies for genome research. In June 1996, he founded the Montreal Genome Centre based at the McGill University Health Centre Research Institute. In 2003, this group expanded to become the McGill University and Genome Quebec Innovation Centre. Dr. Hudson and his team were founding members of the International Haplotype Map Consortium. Dr. Hudsons interests in human genetic diseases focus on the dissection of complex genetic diseases. Disease projects in Dr. Hudsons laboratory included the search for genes predisposing to lupus, inflammatory bowel disease, coronary artery disease, asthma, diabetes and colon cancer. The laboratory also used the DNA-chip technology to characterize breast and ovarian cancer.

In 2007, Dr. Hudson was appointed to the rank of professor (status-only) in the Department of Molecular Genetics at the University of Toronto. He taught in the departments of Human Genetics and Medicine at McGill University and practiced medicine at the McGill University Health Centre Montreal General Hospital.

Dr. Hudson is a fellow of the Royal Society of Canada. He was one of the co-founding members of P3G and is currently serving as its scientific director. He is editor-in-chief of the journal Human Genetics.

The recipient of numerous awards, Dr. Hudson has received the 2005 Achievement of the Year in Healthcare from Macleans magazine, the 2005 Award for Research in Immunology by the Canadian Society for Allergy and Clinical Immunology, the Andr-Dupont 2002 Young Investigator Award given by Quebecs Clinical Research Club, an Investigator Award from the Canadian Institutes of Health Research, a Burroughs-Wellcome Clinician-Scientist Award, The 2002 Prix de la Sant from the Armand-Frappier Foundation, the 2001 Young Scientist Award by the Genetics Society of Canada, the 2000 Scientist of the Year by Radio-Canada, and the 1999 Canadas Top 40 Under 40.

http://oicr.on.ca/person/oicr-investigator/tom-hudson

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HudsonAlpha Institute for Biotechnology

Open letter to president on biotechnology bill – New Vision

We need home-grown scientific, technological and innovation revolution to wean ourselves from dependency on foreign simple technologies.

OPINION | BIOTECHNOLOGY

By Arthur Makara

I would like to appreciate your continuous, relentless efforts to harness science, technology and innovation in Uganda for socio-economic transformation.

We, scientists appreciate your recent intervention by creation of a fully-fledged Ministry of Science, Technology and Innovation (MoTI) and choosing for it a competent Minister Hon. Dr. Elioda Tumwesigye.

As the Ministry puts its foot on the ground, it needs your continuous support to build this sector that is a cornerstone of Ugandas transformation into a middle status economy in the near future. Your Excellency, as the Minister of Science and Technology started his work, one of the tasks the Minister of Finance, Planning and Economic Development was more than happy to pass over to him is the National Biotechnology and Biosafety Bill 2012.

This is because the issues of science had been largely a burden to the Ministers in the Ministry of Finance. Whereas Honorable Kasaija had come to appreciate the science the bill is meant to regulate there are other Ministers in the Ministry of Finance that irrespective of it being their responsibility to understand it, chose the anti-science stance, and continue to mobilize against this Government bill. This is not in line with Government Policy which was approved by Cabinetthe National Biotechnology and Biosafety Policy 2008.

Moreover, they are in cohort with foreign forces led by one Opiyo Oloya based in Toronto, Canada who irrespective of living in a Country that has immensely developed due to technological advancements, fails to appreciate and later alone borrow progressive lessons for Uganda from what goes on around him, only choosing to advance the interests of a the burgeons of the developed world, whose hidden interest is to keep Africa poor through the organic and small-scale farmer movements.

Oloya and his extensions in Uganda, the anti-science activist groups are now thrown in a state of confusion because of your clear supportive position of the enactment of the National Biotechnology and Biosafety Bill into law.

They thrive on spreading misinformation to the largely ignorant and gullible members of the public including some legislators do understand that it is scientific advancements that transform societies. It is the science outcomes from China, India, Korea, USA, Brazil, Europe and India that we consume on a daily basis, making our economies in Africa very weak due to hemorrhage of our currencies.

We need home-grown scientific, technological and innovation revolution to wean ourselves from dependency on foreign simple technologies, and to strengthen our currency through more local consumption and more exports.

We are markets for the developed economies, thus, they support anti-progress propaganda. I appreciate your recent interest in supporting youth groups, to sharpen up their skills and to improve on quality of home-made products. That is the right way to go in the direction of transformation.

Your Excellency, Opiyo Oloya published a veiled article against the National Biotechnology and Biosafety Bill on Wednesday 26th July in the New Vision covering it with the Tea estates in Kabalore and Kyenjojo preferring to call it organic Ugandan tea. He made a false and scientifically disputable claimdrink Ugandan tea, live longer.

And advocates that that should be the brand for Ugandan tea. Whereas this could be potentially true, Opiyo Oloya has no capacity to generate data to support this claim. It has to be scientists to do it, yet he does not trust them. For that brand to stand, it has to be backed by scientific evidence, as other countries will protest against it.

Moreover, I got surprised that Opiyo Oloya could appreciate large-scale commercial farming of any crop, yet he is a champion of small-scale, his grand-mother chicken type of agriculture. He and his anti-science allies are vehemently opposed to large-scale commercial farming preferring to call it monoculture, yet Ugandan policy is to transform from subsistence to commercial agriculture.

So, which policy are they advancing?

Now had Mr. Opiyo Oloya forgotten that the tea he was praising is a monoculture? Mr. Opiyo Oloya knows well that Your Excellency, you are too informed to be confused with his rhetoric, and that is why he is veiling his propaganda against the National Biotechnology and Biosafety Bill 2012 under Mukwano and Igara tea.

He also knows clearly that Ugandan tea is not organic, if we go by the definition of the global organic movement. The tea estate owners have not claimed that their tea is organic but he is pushing that narrative to fit his ill-convened interests. The tea estates owners apply fertilizers, they spray against tea diseases tea leaf rot caused by fungi Corticium invisum and C. thae), the tea red leaf rust caused by fungus Cephalarus mycoidea, black root caused by fungus Rosellina areuata.

These are controlled by use spraying with of large quantities of fungicides. Tea also has pests and vermin such as mites, leafhoppers, aphids and snakes that are controlled through spraying of pesticides and acaricides. These sprays are done at regular intervals or as and when such diseases and pests become rampant.

Ugandan tea is therefore referred to as conventional tea in the organic world. And the biotech revolution that Opiyo Oloya and his allies in Uganda are fighting has potential to make the Ugandan tea to be grown more organicallyparticularly if diseases and pests of tea are addressed through breeding of quicker maturing, disease resistant and robust tea verities, lesser pests and fungicides will be used on it. The primary strategy of Oloya and some uninformed leaders is to block any opportunity for this to be realized in order to serve their private interests.

Your Excellency, we in the science world appreciate the fact that you understand the intensions of such groups and individuals. We acknowledge and appreciate the remarks in support of science the science of biotechnology that you made when you were opening the 25th Source of the National Agricultural and Trade show in Jinja on Tuesday 18th July 2017.

We are comforted by the fact that with your foresighted leadership, the farmers will soon start benefiting from the efforts of your scientists through crop improvement after that enactment of the National Biotechnology and Biosafety Bill into law that will guide and regulate their work. Oloya the expert of everything and his anti-science allies should be ignored for a brighter future of Uganda.

For God and My Country.

The writer is the Executive Director of the Science Foundation for Livelihoods and Development

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Open letter to president on biotechnology bill - New Vision

Drug-Resistant ‘Superbug Gonorrhoea’ Is Emerging, WHO Warns – Healthy Magazine

By Dr. Dominic Rowley, Medical Director, LetsGetChecked

Untreatable strains of gonorrhoea are rapidly on the rise, the World Health Organization (WHO) has warned. At least three people worldwide are infected with an untreatable superbug strain of gonorrhoea, fuelling fears that last-resort treatment will be useless.

Gonorrhoea is the second most common bacterial sexually transmitted disease (STD) in the US after chlamydia, with almost 400,000 confirmed cases reported by the Centers for Disease Control and Prevention (CDC) in 2015, representing a 13% increase from 2014. Last year, the WHO estimated that over 78 million people worldwide contracted gonorrhoea last year, with men and women under 25 being the most affected.

Gonorrhoea is an incredibly virulent infection and it spreads through unprotected vaginal, oral or anal sex, along with the sharing of sex toys that have not been washed properly or covered with a new condom. Troublingly, many of those who contract the disease experience no symptoms, but if left untreated can lead to pelvic inflammatory disease, ectopic pregnancy and infertility, as well as increasing the risk of getting HIV.

Gonorrhoea is a very smart bug. Every time you introduce a new type of antibiotic to treat it, this bug develops resistance to it, Teodora Wi, a human reproduction specialist at the WHO.

Antibiotic Resistance simply refers to when a bacterium can resist the effects of an antibiotic drug that was previously successfully in treating it.

Between 2009 and 2014, the WHO discovered widespread resistance to first-line antibiotics for gonorrhoea, along with increasing resistance to other antibiotic drugs, such as azithromycin, and worryingly, the emergence of resistance to last-resort treatments known as extended-spectrum cephalosporins (ESCs).

In most countries, it said, ESCs are now the only antibiotics that remain effective for treating gonorrhoea. Yet resistance to them has already been reported in 50 countries. There is a pressing need for new medicines. However, the pipeline is very thin and with reports of only potential new gonorrhoea drugs in development, there is no guarantee any will prove effective.

To control gonorrhoea, we need new tools and systems for better prevention, treatment, earlier diagnosis, and more complete tracking and reporting of new infections, antibiotic use, resistance and treatment failures, said Marc Sprenger, director of antimicrobial resistance at the WHO.

Since the introduction of antibiotics in 1930s, gonorrhoea has shown a remarkable ability to always stay ahead of our most effective antibiotics.

As gonorrhoea becomes more and more difficult to treat, this is having significant impacts on the healthcare system due many patients being asymptomatic. A big part of the problem is that many STDs do not show symptoms, so people may not know that they have gonorrhoea and are infecting others.

With there being no guarantee that there is an effective treatment close to being made available, our focus must shift to what we can do to stay protected.

As always, it is important to practice safe sex with condoms, open communication with partners, and regular sexual testing, especially when entering into new relationships. Sexual health testing can be accessed through your local physician or clinic, or you can visit LetsGetChecked.com for a convenient and confidential test delivered directly to your location.

Symptoms in men:

Symptoms in women:

About LetsGetChecked

LetsGetChecked provides convenient and confidential at-home diagnostic tests enabling you to manage your health from the comfort of home. Our revolutionary service, allows you to order specialized or routine tests and then monitor, track and improve your personal health from a secure online portal. You will receive the same level of clinical care, only through a secure personalized dashboard. LetsGetChecked customers can order tests online, by visiting LetsGetChecked.com

LetsGetChecked partners with leading international laboratories for testing who are CLIA, CPA, INAB approved and CAP accredited, the highest levels of accreditation, to provide customers with convenient and accurate, personal health testing.

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Drug-Resistant 'Superbug Gonorrhoea' Is Emerging, WHO Warns - Healthy Magazine

New class of drugs targets aging to help keep you healthy – CNN

Story highlights

"This is one of the most exciting fields in all of medicine or science at the moment," said Dr. James Kirkland, director of the Kogod Center on Aging at the Mayo Clinic and lead author of the new paper.

Senescent cells play a role in many age-related chronic diseases, such as diabetes, cardiovascular disease, most cancers, dementia, arthritis, osteoporosis and blindness, Kirkland said. Therefore, senolytic drugs are a possible treatment approach for such diseases.

As a practicing physician, Kirkland said that he has grown increasingly concerned for his patients who are sick with many of these age-related conditions.

"The same processes that cause aging seem to be the root causes of age-related diseases," he said. "Why not target the root cause of all of these things? That would have been a pipe dream until a few years back."

Fourteen senolytic drugs have been discovered and are being actively studied, 11 of which Kirkland's colleagues and their collaborators found, he said.

Are these age-modifying drugs ready for human trials?

Scientists have long known that certain processes influence your body's aging on the cellular level, according to the paper. Those processes include inflammation, changes in your DNA, cell damage or dysfunction and the accumulation of senescent cells.

It turns out that those processes are linked. For instance, DNA damage causes increased senescent cell accumulation, Kirkland said.

So an intervention that targets senescent cells could attenuate other aging processes as well, according to the new paper. That is, once such an intervention is tested for efficacy and safety.

"I think senolytic drugs have a great future. If it is proven that it can reduce senescent cells and rejuvenate tissues or organs, it may be one of our potential best treatments for age-related diseases," said Dr. Kang Zhang, founding director of the Institute for Genomic Medicine at the University of California, San Diego, who was not involved in the new paper.

Yet taking senolytic drugs from mouse studies to human ones is a "big leap," Zhang said.

"So we will have to wait for clinical trials to see whether this would work in humans," he said. "One possible clinical trial strategy is to test this class of drugs in an age-related disease, such as neurodegeneration, like Parkinson's disease, to see if it can reduce clinical severity of the disease and improve tissue functions."

In the new paper, the researchers wrote that potential clinical trial scenarios include testing whether senolytic drugs could alleviate multiple chronic diseases in a single patient or whether such drugs could treat conditions that involve senescent cell accumulation in one location in the body, such as osteoarthritis.

Other potential clinical trial scenarios include testing whether the drugs could alleviate frailty in older adults or could treat conditions associated with chemotherapy or radiotherapy, since radiation can produce cellular senescence, Kirkland said.

For instance, "in mice, if you treat one leg with enough radiation, after three months, the mouse has trouble walking. If you give a single dose of these drugs, they're able to walk quite well, and that persists for two years," he said. "These drugs could mitigate the effects of therapeutic radiation."

"Some of the drugs at the moment are moderately expensive," he said.

"If we're able to reduce hospitalizations ... the savings on the medical care and hospital side might more than offset the cost of these drugs by a longshot," Kirkland said, though it remains unclear what the dosage options would be for senolytic drugs for short- or long-term use.

As for how soon he thinks human clinical trials might commence, Kirkland said doctors could have an idea of how well senolytic drugs work for serious health conditions in about a year and a half or two years.

Once the drugs are tested in humans, researchers expect many companies to be lining up to develop or manufacture senolytic drugs. Some have already expressed interest.

"In the coming decades, I believe that health care will be transformed by this class of medicine and a whole set of diseases that your parents and grandparents have will be things you only see in movies or read in books, things like age-associated arthritis," said David, whose company was not involved in the new paper.

Yet he cautioned that, while many more studies may be on the horizon for senolytic drugs, some might not be successful.

"One thing that people tend to do is, they tend to overestimate things in the short run but then underestimate things in the long run, and I think that, like many fields, this suffers from that as well," David said.

"It will take a while," he said. "I think it's important to recognize that a drug discovery is among the most important of all human activities ... but it takes time, and there must be a recognition of that, and it takes patience."

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New class of drugs targets aging to help keep you healthy - CNN

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Singing May Be Good Medicine for Parkinson's Patients – Anti Aging News

Sometimes modern medicine and miracle drugs are the answer. Sometimes the remedies simply require a much more common sense approach. Obviously, singing requires muscle and breathing control. It helps exercise and strengthen muscles that arent used during regular conversation. Since all of these functions are affected negatively by Parkinsons Disease, it only makes sense that singing, a fun activity, would help those with this horrible disease, Editor,www.WorldHealth.net.

(HealthDayNews) -- Singing? To benefit people with Parkinson's disease? It just may help, a researcher says.

"We're not trying to make them better singers, but to help them strengthen the muscles that control swallowing and respiratory function," said Elizabeth Stegemoller, an assistant professor of kinesiology at Iowa State University.

Stegemoller holds a weekly singing therapy class for Parkinson's disease patients. At each session, participants go through a series of vocal exercises and songs.

Singing uses the same muscles as swallowing and breathing control, two functions affected by Parkinson's disease. Singing significantly improves this muscle activity, according to Stegemoller's research.

"We work on proper breath support, posture and how we use the muscles involved with the vocal cords, which requires them to intricately coordinate good, strong muscle activity," she said in a university news release.

Other benefits noted by patients, their families and caregivers include improvements in mood, stress and depression, Stegemoller said.

Her research was published inComplementary Therapies in Medicine.

Parkinson's disease is a chronic and progressive movement disorder. Nearly one million Americans live with the disease. The cause isn't known, and there is no cure at present. But there are treatment options such as medication and surgery to manage symptoms, according to the Parkinson's Disease Foundation.

Symptoms can include tremors of the hands, arms, legs, jaw and face; slowness of movement; limb rigidity; and problems with balance and coordination.

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Singing May Be Good Medicine for Parkinson's Patients - Anti Aging News

New Study Shows Gut Bacteria Produces Secret, Anti-Aging Molecules – Wall Street Pit

When we were young, we viewed our parents like they were the most powerful human beings in the world.

They exuded health, strength, such admirable quickness of mind in answering our endless questions, and the might to balance career and family.

How did they do it?

That used to puzzle us, as we kept getting delighted in the thought that we had extraordinary human beings playing the role of mom and dad.

At first, we begin to blame our society or the world in general for the wealth of new and challenging problems that people are forced to face everyday. Then, gradually we begin to realize that life for our parents after all, wasnt as easy as we had perceived it when we were young.

As the years go by, with us having our own families, and going through the same stressful phases that our parents had gone through, its right then we start to realize that the weaknesses and diseases that came to plague our mom and dad would also be our unavoidable fate.

Were all destined to grow old.

Today, the global anti-aging industry is worth more than $140 billion and has been predicted to rise to nearly $217 billion by 2021.

The worlds leading companies, including Google, are involved in anti-aging research and treatment of age-related diseases.

From Senescence Info, heres a list of some of these companies and their anti-aging endeavors:

Now, whats new?

The discovery, this time, is not about yeast, telomeres, stem cells, or genes.

Its about molecules. To be exact, a molecule type thats produced by commensal bacteria and one which has the ability to extend healthspan.

Commensal bacteria are living organisms that derive their food from other living organisms. But, unlike parasites, they do not harm or hurt their host. This type of bacteria, also known as commensal microflora, usually inhabit the gut, respiratory tract, and skin.

In humans, the number of commensal bacteria that colonize our skin and mucosal surfaces is greater than the number of cells forming our body.

However, this molecule called indole, which was discovered by researchers at the Emory University School of Medicine, came from commensal bacteria that the team studied in the gut of worms (Caenorhabditis elegans), mice, and fruit flies to determine its anti-aging properties.

According to the authors, and as published on PNAS, the small molecules [which are shown to be] produced by the microbiota and related to indole extend healthspan in geriatric worms, flies, and mice, without attendant effects on lifespan. Indoles act via the aryl hydrocarbon receptor (AHR) and cause animals to retain a youthful gene expression profile. Indoles may represent a new class of therapeutics that improve the way we age as opposed to simply extending how long we live.

Indoles and AHR are also found in the human body. The former exists in humans and mammals in small quantities, produced from plant dietary sources and intestinal microbiota. Whats more fascinating about indole is that it can extend not only an organisms healthspan, but fecundity and reproductive span as well.

The study is statistically extremely robust, remarks Dario Valenzano of the Max Planck Institute for Biology of Ageing. The paper convincingly shows that the lack of indoles is detrimental to healthspan. What will be interesting is to see if the same effect holds good with wild-type animals treated [extraneously] with indoles.

Indeed, its a remarkable discovery. But, mankind appears to unfortunately, still have a long way to go in their quest for longer, healthier life.

As study author Daniel Kalman notes: It is a long road to go from the data we present to a drug. That takes careful development, testing, and safety and efficacy trials.

Despite the relatively long road ahead (I say relatively based on the fact that AI applications are on a seemingly rapid upward trajectory and anything is possible. We may have a breakthrough tomorrow or five years from, nobody knows for sure) the fact that new advancements in modern technology are finally offering up some real promising possibilities for ways to reverse aging as a process, is a breakthrough in anti-aging research and the right step toward a healthier, longer life and consequently, a brighter future for all of us.

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New Study Shows Gut Bacteria Produces Secret, Anti-Aging Molecules - Wall Street Pit

SRU completes busy summer of campus improvements – Allied News

SLIPPERY ROCK - While students returning to Slippery Rock University for the fall semester may have noticed a few physical changes to the campus exterior, the most visible changes have occurred on building interiors and student's computer screens.

The most noticeable of all exterior changes that occurred over the summer was the demolition of the former Kraus Hall. Built in 1966, the hall, located on Main Street, was originally known as "The Riviera," a privately owned facility belonging to Stanley Kraus. Kraus donated the hall to the University in 1982. The hall, valued at $4.5 million at that time, was the largest gift ever received by the University. It continued to house students until 2009. It was demolished at a cost of approximately $150,000.

The now empty lot will be used as a staging area for materials and trailers when the renovation projects for SRU's performing arts buildings - Miller Auditorium, East Gym and West Gym - begin later this year. Long-term plans for the former Kraus Hall space are undetermined.

Projects that either started during the summer or were scheduled to start, including a $6.5 million renovation to the Strain Behavioral Science Building, will continue during the fall. However, according to Scott Albert, assistant vice president of facilities, planning and environmental safety, the value of completed improvements on campus during the summer was estimated at $6 million.

"It was one of our busiest summers because of the timing of projects," Albert said. "Overall, if you look at the volume of construction that's been ongoing, year to date and, with the BSB and performing arts projects kicking off, it'll be close to one of our busiest overall years in the past 20 years."

The first phase of a $4 million improvement project for Bailey Library was completed during the summer, which included the renovation of the second and third floor restrooms that were closed during the summer. Ongoing improvements, which will continue through the fall, include an additional computer lab and study spaces, a redesigned entryway and an expanded caf. The project is scheduled for completion in December.

"From a cost perspective, Bailey was the biggest project of the summer," Albert said. "When all the projects are completed, it'll provide an exciting and modern look to the campus. Until then, we appreciate everyone's patience."

Other significant changes from the summer included second floor renovations to Rhoads Hall; improved accessibility to the Gail Rose Lodge; the replacement of the Swope Music Hall loading dock; and asphalt maintenance and seal coating to several parking lots. An underground condensate line, that returns water from the McKay Education Building to the boiler plant, was also replaced. Restoration work from that project continues near Old Main.

There were also considerable upgrades related to classrooms, technology and sustainability:

Students may notice changes in lighting, as the University continues to switch completely over to LED lighting, which uses less energy and lasts longer.

Eight classrooms were upgraded with new technology, including items such as laser projectors and digital audio controls. The upgraded classrooms included two each in the Eisenberg Classroom Building, the School of Physical Therapy Building, Spotts World Culture Building and the Advanced Technology and Science Hall. A "Concepts of Sciences Lab" was created in Room 130 of ATSH while Room 103 of Spotts was converted from a classroom to a computer lab.

More than 700 computers were replaced in academic buildings, making this year one the largest-scale overhauls in recent years as most computers are replaced on a three-year cycle.

As part of yearlong upgrades, 350 Wi-Fi access points were replaced in various academic buildings and the Smith Student Center that will give students stronger connections with more bandwidth. An additional 250 access points are scheduled to be replaced in other campus buildings this academic year.

See a gallery of photos at: http://www.sru.edu/news/083117a

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SRU completes busy summer of campus improvements - Allied News

Mayor Jim Kenney wants to clean up 'Filthadelphia' and he's enlisting Penn's help – The Daily Pennsylvanian

Photo: Matt Rourke

The Philadelphia mayor's office has unveiled an expansive plan to clean up Filthadelphia, and they're enlisting Penn's help.

The Zero Waste and Litter Action Plan, initiated by Philadelphia Mayor Jim Kenney, aims to reduce litter in the city and end the citys use of landfills and conventional incinerators by 2035. To implement the plan, the Kenney administration partnering with various local institutions including Temple University, Swarthmore College and Penn.

Litter is an issue that has plagued Philly for a very long time, Nic Esposito, the director of Phillys Zero Waste Plan said. Being that we have so much crossover with [Penns] sustainability office and now with some of their research, were exciting to be working with Penn on this issue.

Penn political science professor Dan Hopkins has been enlisted as an academic partner to work on the reduction of litter.

As a member of the projects behavioral science subcommittee, Hopkins conducts experiments throughout the city to better understand what motivates people to recycle and how the placement of trash cans in public spaces can reduce littering.

Ive been excited to see behavioral science integrated in this work from the ground up, Hopkins said. The city had the foresight to bring us in not just on the back end to analyze what happened afterwards, but from the very beginning so we can provide advice about what policies would be more or less useful.

The Kenney administration devised the Zero Waste 2035 campaign late last year, but Penn has been working to clean up its campus for several years now.

In 2014, Penn launched the Climate Action Plan 2.0, which aimed to divert more than 90 percent of Penn's away from landfills. The initiative also aims to increase student awareness on sustainability and climate change, promote sustainable design and reduce solid waste.

College junior Karen Chi is a member of the Eco-Reps program, which engages students to work on small projects that advance the goals of Climate Action Plan 2.0.

Chi said while Penn keeps its campus fairly litter-free, she thinks more trash cans could be placed near food trucks since they generate a large amount of waste. Chi isn't alone; several other student groups on campus say more needs to be done to make Penn a truly clean and green campus.

The Penn Environmental Group advocates for the establishment of a green fund, which would set aside a portion of University revenue for future, large-scale green initiatives such as increasing the use of solar panels around campus, and adding gardens and water-collection technology to buildings.

We want to make sure its targeted and doesnt become another research fund that students dont know about or understand, but specifically a fund that will be making Penn more sustainable and innovative, said Susan Radov, political director of the Penn Environmental Group and College junior.

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Mayor Jim Kenney wants to clean up 'Filthadelphia' and he's enlisting Penn's help - The Daily Pennsylvanian

Nanomedicine Research Journal

Nanomedicine Research Journal (Abbreviation: Nanomed Res J)

is an international, open access, peer-reviewed, electronic and print quarterly publication released by the Iranian Society of Nanomedicine (ISNM). Nanomedicine Research Journal publishes original research articles, review papers, mini review papers, case reports and short communications covering a wide range of field-specific and interdisciplinary theoretical and experimental results related to applications of nanoscience and nanotechnology in medicine including, but not limited to, diagnosis, treatment, monitoring, prediction and prevention of diseases, tissue engineering, nano bio-sensors, functionalized carriers and targeted drug delivery systems.

* Publication process of manuscripts submitted to Nanomed Res J is free of charge.

To see Acceptance timeline Please follow the link below:

Acceptance Timeline Diagram

About the publisher

Founded in 2011 by the leading ofSchool of Advanced Technologies in medicine (SATiM),Tehran University of Medical Sciences (TUMS) and Iran Nanotechnology Initiative Council, the Iranian Society of Nanomedicine (ISNM) attempts to promote and develop medical nanotechnology in Iran. For more information about the publisher, please visit us at http://isnm.ir/en/.

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Nanomedicine Research Journal

Molecular nanosubmarines can target and kill specific cancer cells – New Atlas

In 2015, scientists from Rice University revealed they had created light-driven nanosubmarines. These tiny molecular machines were activated by ultraviolet light and based on earlier work from Nobel laureate Bernard Feringa, whose ground-breaking research won the prize for chemistry in 2016. These single-molecule machines have now been shown to be able to target, and drill into, specific cancer cells, paving the way for a variety of highly targeted future nanomedicine treatments.

These molecular machines consist of 244 atoms with a tail-like propeller that creates propulsion when exposed to UV light. After proving the concept worked back in 2015, the team moved on to exploring whether the molecular motor could penetrate an individual cell.

"We thought it might be possible to attach these nanomachines to the cell membrane and then turn them on to see what happened," explains chemist James Tour.

First the team needed to attach the molecular motor to a component that allowed it to target a specific cell. In these early experiments a peptide was utilized that drove the molecule to attach itself to the membrane of human prostate cancer cells. The molecules were shown to effectively locate and attach to the targeted cells, but not drill into them until specifically triggered by UV light. Once triggered, the motors spun up to two to three million rotations per second to break through the cell membrane and kill the cell within one to three minutes.

The obvious challenge that needs to be overcome is to develop an activation trigger other than ultraviolet light, which currently limits the molecular motors to being controllable when concentrated at the surface of tissue. Other triggers are currently being investigated, with near infra-red (IR) light looking like the best option to control these motors when delivered deep into a body.

"In this process, the motor will absorb two photons simultaneously and get enough energy to start the rotor," says Gufeng Wang, a chemist on the Rice University team. "Since near IR light has deep penetration depth, we are no longer limited to the surface of the tissue."

There is much work that still needs to be done before these molecular motors become a real, clinical treatment, but there are a variety of exciting outcomes this technology promises. As well as targeting and destroying cancer cells, the molecular motors could be utilized to deliver drugs directly into diseased cells.

As well as working on additional activation mechanisms, the team is embarking on a series of small animal tests to examine the effectiveness of the molecules on living organisms.

"The researchers are already proceeding with experiments in microorganisms and small fish to explore the efficacy in-vivo," says Tour. "The hope is to move this swiftly to rodents to test the efficacy of nanomachines for a wide range of medicinal therapies."

The research was published in the journal Nature and the video below provides a closer look at the team's breakthrough.

Source: Rice University

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Molecular nanosubmarines can target and kill specific cancer cells - New Atlas

Meditation expert tells us what the science really says and why multitasking is a 'myth' – Southernminn.com

So you fell asleep easily enough, but now it's 3 a.m. Your mind is spinning, and rest is elusive. You're reliving every foolish or embarrassing thing you did in the past 24 or 48 or 72 hours, and that is a lot of material to run through. And you simply can't stop.

Except maybe you could, if only you knew how to be mindful.

"When you're caught in that loop of rumination, that's very real, and it creates very intense feelings," explains psychologist and journalist Daniel Goleman, who reported on brain and behavioral sciences for the New York Times. "If you're mindful, you realize it's just a thought. You don't have to believe your thoughts. You can question them, and that changes them. It takes energy from the brain that creates the heaviness. Looking at it in a different way makes the rumination less intense."

You might think, on hearing such praises of mindfulness a form of meditative practice that it will solve just about every problem in your life. Meditation can halt the late-night rumination cycle, right? So can't it also make you into a better person? Enlarge your brain? Make you taller and thinner and richer?

Well, no, says Goleman, who's also the author of the best-selling book "Emotional Intelligence." Some claims of meditation's power are overblown. Some studies are less rigorous than they should be. But science has proven that meditation can induce healthy and important physical improvements, such as lowering your blood pressure, decreasing relapses into depression and managing chronic pain.

Which leaves us with a question: As our interest in meditation grows, how do we know what's too good to be true?

Goleman has some answers. With Richard J. Davidson, who directs a brain lab and founded the Center for Healthy Minds at the University of Wisconsin-Madison, Goleman has just published "Altered Traits: Science Reveals How Meditation Changes Your Mind, Brain, and Body" (Avery, $27). The book separates truth from fiction, debunking studies and highlighting truth about meditation's startling effects on the brain.

"Altered Traits" also chronicles the authors' decades-long friendship and lifelong interest in the subject of meditation, which began at a time during which scientific circles had little patience or interest in the subject.

The book is important because it represents "the coming together of two very important voices," says Scott Rogers, founder and director of the Mindfulness and Law Program at the University of Miami School of Law. He will be in conversation with Goleman at Miami Dade College.

Rogers, co-founder of UMindfulness, the university's inter-disciplinary collaboration that marries research to training, notes another benefit: Not only are Goleman and Davidson experts in their fields, they're also meditation practitioners.

"We need responsible, reasoned voices speaking from a variety of perspectives, and here we have the hard science and the journalist, and both are practitioners. We need a book we can look to as a reliable source of information," Rogers says. "They both practice and have for a long time. A lot of researchers have been interested in this over the last 10 or 15 years, but they haven't historically practiced mindfulness. There are a bunch of people practicing, but they're not scientists."

"Altered Traits" examines scientific studies on meditation and the benefits of intensive retreats, learning to view our selves and our brains in a whole new light and the importance of a good teacher ("I feel strongly the quality of the teacher is important," Goleman says). The book also challenges notions we (or at least our bosses) hold dear, such as the idea that multitasking is a positive endeavor.

"Multitasking is a myth," Goleman says. "You can't really do two things at once. What happens is your brain switches rapidly. As it switches, you lose the power of your concentration. You do many things at once, you do them less well."

But there is good news for multitaskers, according to "Altered Traits": Cognitive control can be improved. One test of undergrad volunteers tried short sessions of focusing or breath-counting. "Just three 10-minute sessions of breath counting was enough to appreciably increase their attention skills on a battery of tests. And the biggest gains were among the heavy multitaskers, who did more poorly on those tests initially," the authors write.

Which brings up another important question: If the benefits of meditation expand the deeper a person's practice goes, is meditating in short sessions still useful?

"Casual practice helps you in surprising ways, but the deeper you go and the more you practice, the more benefits you get," he says. "The research shows that right from the beginning mindfulness practices counter the ill effects of multitasking. We're all doing so many things a day. But the improvement in attention starts at the beginning."

And if you can only spare 10 minutes at a time for meditation, Goleman suggests spreading your practice throughout the day.

"Intersperse it through the day. Ten minutes in the morning. Ten at lunch. Ten at night. The effect is prolonged. If you can do 20 minutes, even better. If you can do it for a year, that's good. Five years is even better."

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Meditation expert tells us what the science really says and why multitasking is a 'myth' - Southernminn.com

Losing weight for the couch potato and others – The Washington Post – Washington Post

Over the years, Robert Kushner has seen many obese patients get tripped up trying to keep pounds off because they rely on fast food, juggle too many tasks and dislike exercise.

So Kushner, an obesity expert, began helping patients plan diet and physical activity around their lifestyles and habits.

We dont necessarily put people on any specific diet; it really gets to what is their life, what are their struggles, he said. We believe obesity care cant be inconsistent with culture, family or how you lead your life.

He recently suggested that a patient split meals with his wife when they dined out, rather than each having large portions or avoiding restaurants entirely. When the man said he was uncomfortable sharing a meal with his wife when the couple was out with friends, Kushner said to do it anyway.

I said, Its a strategy that works whether youre with other people or not. ... Be assertive, said Kushner. I think people dont think about it because they just arent raised to share.

The patient kept track of the foods he was eating, learning to avoid larger portions and fattening dishes. He has lost 15 pounds in six months, cutting about 500 to 700 calories per day.

More than a third of U.S. adults are obese, according to a 2015 report from the Centers for Disease Control and Prevention.

Kushner, who directs the Center for Lifestyle Medicine at Northwestern Medicine in Chicago, said he realized in the 1980s that obesity was a looming problem. He started combining diet, nutrition, exercise and behavioral changes into a plan for patients.

Since then, whats changed is the maturity of the area, understanding more about the effects of stress and sleep on body weight, and some of the behavioral-change techniques have expanded, he said.

In addition to promoting good sleep habits and stress management techniques such as meditation, Kushner and his colleagues suggest bariatric surgery for patients with a body mass index of 40 or more and for some who are less obese but who have medical problems such as Type 2 diabetes, sleep apnea and heart disease. They also recommend medication for patients with BMIs as low as 30 who have additional medical problems or have failed to lose weight despite lifestyle changes.

Kushner said patients often have trouble shedding pounds unless problems like stress are managed.

Kushners approach proposes gentler, moderate changes. Rather than tell patients to cut out every unhealthy food they love, Kushner suggests focusing on alternatives with higher fiber and water content but fewer calories. (Think beans, vegetables, salads, fruits, broth-based soups and whole grains such as oatmeal.)

For the couch potato who finds exercise overwhelming, Kushner advises walking for short periods, building up to three 10-minute brisk walks daily to boost your energy level and mood while you also burn calories.

He also suggests that dog owners walk their pet for 30 minutes daily rather than leave Fido in the back yard. Kushner found that dog-walking helped overweight and obese people lose weight in a study, and he wrote a book about it Fitness Unleashed!: A Dog and Owners Guide to Losing Weight and Gaining Health Together with veterinarian Marty Becker.

I call it an exercise machine on a leash, Kushner said. It is a way for people to think about moving their body around in a fun way.

Most of his patients lose about 10 percent of their body weight (some more than 20 percent) after six months and keep it off during the program, Kushner said.

Patients say they feel understood and more motivated as they are given personalized direction to make positive changes in their lifestyle, he said.

Kushner created a questionnaire to screen patients for traits that prevent weight loss such as eating whats convenient rather than planning healthy meals or having an all-or-nothing mentality traits that Kushner and colleagues found in a study to be strongly linked with obesity.

Once you take the quiz and know your factor type, I can personalize a plan to help you lose weight and keep it off, Kushner said.

Another way Kushner hopes to help patients tackle obesity is by teaching medical students about treating and preventing it. He found in a recent study that the U.S. Medical Licensing Examination was focusing much more on diagnosing and treating obesity-related illnesses, such as Type 2 diabetes and sleep apnea, than on how to counsel patients on diet, physical activity, behavior changes, the use of medications and bariatric surgery.

But Kushner said his approach isnt only about weight loss.

We know that as little as 5 to 10 percent weight loss will improve the health and well-being of individuals and can also improve blood sugar, blood pressure, the fats in your blood, arthritis or reflux symptoms, as well as your mood and energy level.

Read more

Changing your perspective about weight loss may change the outcome, too

A weight-loss expert changes his tune: Focus on enjoyment, not perfection

Weight loss, especially with surgery, tied to lower risk of heart failure

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Losing weight for the couch potato and others - The Washington Post - Washington Post

Self-driving cars still can't mimic the most natural human behavior – Quartz

What do you need to build a self-driving car? Roboticists and computer scientists have generally settled on similar requirements. Your autonomous vehicle needs to know where the boundaries of the road are. It needs to be able to steer the car and hit the brakes. It needs to know the speed limit, be able to read street signs, and detect if a traffic light is red or green. It needs to be able to react quickly to unexpected objects in its path, and it gets extra points if it knows where it is on a map.

All of those skills are important and necessary. But by building from a list of technical requirements, researchers neglect the single most important part of real-world driving: our intuition. Using it to determine the motivations of those around us is something humans are so effortlessly good at that its hard to even notice were doing it, nonetheless program for it.

A self-driving car currently lacks the ability to look at a personwhether theyre walking, driving a car, or riding a bikeand know what theyre thinking. These instantaneous human judgments are vital to our safety when were drivingand to that of others on the road, too.

As the CTO and cofounder of Perceptive Automata, an autonomous-vehicle software company started by Harvard neuroscientists and computer scientists, I wanted to see how often humans make these kinds of subconscious calls on the road. I took a camera out to a calm intersection near my former lab at Harvard with no traffic signals. It is not by any stretch of the imagination as congested or difficult as an intersection in downtown Boston, let alone Manhattan or Mexico City. But in 30 seconds of video, it is still possible to count more than 45 instances of one person intuiting whats in the mind of another. These non-verbal, split-second intuitions could be that person is not going to yield, that person doesnt know Im here, or that person wouldnt jaywalk while walking a dog. Is that bicyclist going to turn left or stop? Is that pedestrian going to take advantage of their right-of-way and cross? These judgments happen instantaneously, just watch.

We have lots of empirical evidence that humans are incredibly good at intuiting the intentions of others. The Sally-Anne task is a classic psychology experiment. Subjectsusually childrenwatch a researcher acting out a scene with dolls. A doll named Sally hides a marble in a covered basket. Sally leaves the room. While Sally is gone, a second dollAnnesecretly moves the marble out of the basket and into a closed box. When the first doll comes back, children are asked where she will look for the marble. Its easy to say, Well, of course shell still look in the basket, as Sally couldnt have known that the marble had moved while she was gone. But that of course is hiding an immensely sophisticated model. Children have to know not only that Sally is aware of some things and not of others, but that her awareness only updates when she is able to pay attention to something. They also have to know that her mental state is persistent, even when she leaves the room and comes back. This task has been repeated many times in labs around the world, and is part of the standard toolkit researchers use to understand if somebodys social intuitions are intact.

The ability to predict the mental state of others is so innate that we even apply it to distinctly non-human objects. The Heider-Simel experiment shows how were prone to ascribe perceived intent even to simple geometric shapes. In this famous study, a film shows two triangles and a circle moving around the screen. With essentially no exceptions, most people construct and elaborate narrative about the goals and interactions of the geometric shapes: One is a villain, one a protector, the third a victim who grows courageous and saves the dayall these mental states and narratives just from looking at geometric shapes moving about. In the psychological literature, this is called an impoverished stimulus.

Our interactions with people using the road are an example of an impoverished stimulus, too. We only see a pedestrian for a few hundred milliseconds before we have to decide how to react to them. We see a car edging slightly into a lane for a half second and have to decide whether to yield to them. We catch a fleeting glimpse of a cyclist and judge whether they know were making a right turn. These kinds of interactions are constant, and they are at the very core of driving safely and considerately.

And computers, so far, are hopeless at navigating them.

The perils of lacking an intuition for state of mind are already evident. In the first at-fault crash of a self-driving vehicle, a Google self-driving car in Mountain View incorrectly assumed that a bus driver would yield to it, misunderstanding both the urgency and the flexibility of a human driver trying to get around a stopped vehicle. In another crash, a self-driving Uber in Arizona was hit by a turning driver who expected that any oncoming vehicles would notice the adjacent lanes of traffic had slowed down and adjust its expectations of how turning drivers would behave.

Why are computers so bad at this task of mind reading if its so easy for people? This circumstance comes up so often in AI development that it has a name: Moravecs Paradox. The tasks that are easiest for people are often the ones that are the hardest for computers. Were least aware of what our minds do best, said the late AI pioneer Marvin Minsky. Were more aware of simple processes that dont work well than of complex ones that work flawlessly.

So how do you design an algorithm to perform a task if you cant say with any certainty what the task entails?

The usual solution is to define the task as simply as possible and use what are called deep-learning algorithms that can learn from vast quantities of data. For example, when given a sufficient number of pictures of trees (and pictures of things that are not trees), these computer programs can do a very good job of identifying a tree. If you boil a problem down to either proving or disproving an unambiguous fact about the worldthere is a tree there, or there is notalgorithms can do a pretty good job.

The only way to solve these problems is to deeply understand human behavior by characterizing it carefully using the techniques of behavioral science.But what to do about problems where basic facts about the world are neither simple nor accessible? Humans can make surprisingly accurate judgments about other humans because we have an immensely sophisticated set of internal models for how those around us behave. But those models are hidden from scrutiny, hidden in the black boxes of our minds. How do you label images with the contents of somebodys constantly fluid and mostly nonsensical inner monologue?

The only way to solve these problems is to deeply understand human behaviornot just by reverse-engineering it, but by characterizing it carefully and comprehensively using the techniques of behavioral science. Humans are immensely capable but have opaque internal mechanisms. We need to use the techniques of human behavioral research in order to build computer-vision models that are trained to capture the nuances and subtleties of human responses to the world instead of trying to guess what our internal model of the world looks like.

First, we need to work out how humans worksecond comes training the machines. Only with a rich, deep characterization of the quirks and foibles of human ability can we know enough about the problem were trying to solve in order to build computer models that can solve it. By using humans as the model for ideal performance, we are able to gain traction on these difficult tasks and find a meaningful solution to this intuition problem.

And we need to solve it. If self-driving cars are going to achieve their promise as a revolution in urban transportationdelivering reduced emissions, better mobility, and safer streetsthey will have to exist on a level playing field with the humans who already use those roads. They will have to be good citize
ns, not only skilled at avoiding at-fault accidents, but able to drive in such a way that their behavior is expected, comprehensible, and clear to other vehicles drivers and the pedestrians and cyclists sharing space with them.

Follow Sam on Twitter. Learn how to write for Quartz Ideas. We welcome your comments at ideas@qz.com.

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Self-driving cars still can't mimic the most natural human behavior - Quartz

Brain researchers in uproar over NIH clinical trials policy – Nature.com

Scientists studying human behaviour and cognitive brain function are up in arms over a plan by the US National Institutes of Health (NIH) to classify most studies involving human participants as clinical trials.

An open letter sent on 31 August to NIH director Francis Collins says that the policy could unnecessarily increase the administrative burden on investigators, slowing the pace of discovery in basic research. It asked the NIH to delay implementation of the policy until it consulted with the behavioural science community. As this article went to press, the letter had garnered 2,070 signatures.

Every scientist I have talked to who is doing basic research on the human mind and brain has been shocked by this policy, which makes no sense, says Nancy Kanwisher, a cognitive neuroscientist at the Massachusetts Institute of Technology in Cambridge, who co-wrote the letter with four other researchers.

The policy is part of an NIH clinical trial reform effort started in 2014 to ensure that all clinical results were publicly reported. The policy is scheduled to go into effect in January 2018. Its definition of a clinical trial included anything involving behavioural interventions, such as having participants perform a memory task or monitor their food intake. Such studies would need special evaluation by NIH review committees and institutional ethics review boards; and the experiments would need to be registered online in the clinicaltrials.gov database.

But many researchers believe that studies of normal human behaviour intended to discover new phenomena rather than alter them should not be classified in this way. Among other concerns, small institutions that do not normally perform clinical trials may not have the resources or knowledge to fully comply.

These concerns are overblown, said Michael Lauer, NIH deputy director for extramural research at a 1 September NIH advisory council meeting in Bethesda, Maryland. The only regulation were talking about is reporting that the trial exists and telling the world about the results. It is as simple as this and as profound as this. He said that his office would work with behavioural scientists to ensure their studies were getting the proper review and that their research could be properly registered.

But advisory council member Terry Jernigan, a cognitive scientist at the University of California San Diego, told Lauer that it was not as simple as that. She said the policy has already caused problems for a study shes leading that tracks normal brain development in adolescents. When her group had the parents sign the required clinical trial consent form, some expressed concerns that the language indicated that something was being done to their children, rather than just having researchers observe them.

The NIH, in response to some of those concerns, will release a list of study examples that qualify as clinical trials under the new policy next week. The NIH definition of a clinical trial may be broader than other clinical trial definitions because it reflects NIH's mission, encompassing biomedical and behavioral outcomes as they pertain to human health, said the NIH in a statement to Nature News. This definition does not encompass all psychological and cognitive research that is funded by NIH.

Jeremy Wolfe, a vision researcher at Brigham and Womens Hospital in Boston, says he is encouraged to hear Lauer say the NIH plans to work with researchers in his field, but says that the details of the policy will be key. Were worried about whether those details can be worked out by the January deadline, he says.

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Brain researchers in uproar over NIH clinical trials policy - Nature.com

The Good Catholic – slantmagazine

Paul Shoulberg's The Good Catholic is billed as a romantic comedy between a young priest, Daniel (Zachary Spicer), and a depressive agnostic musician, Jane (Wrenn Schmidt), but the film's light surface belies a darker confrontation with religious doubt. For a faith-based film, it's notable for giving equal narrative weight to the beliefs and emotions of its only non-Christian character, resisting the urge to patronize Jane by suggesting that her sorrow is symptomatic of her agnosticism and can be cured if she simply found her faith. Certainly it's refreshing to see a film aimed at the Christian community present the allure of the secular world in an unbiased way and allow Daniel to truly struggle to determine his future within the church.

Despite The Good Catholic's interesting macro approach compared to other films of its ilk, it's far less successful on a micro level. The foundation of Jane and Daniel's blooming relationship is particularly contrived, relying on the improbable conceit of a non-Catholic woman not only showing up for confession once but continuing to do so for no plausible reason until she falls in love with the priest. As Jane's fascination with death never materializes into an active interest in Daniel's own all-encompassing spiritual journey, it remains a nagging mystery both why she relentlessly pursues such a deeply devout man, especially given his vow of chastity, and why Daniel is so enamored with someone who's so unconcerned with his own core beliefs.

Despite its interesting macro approach compared to other films of its ilk, its far less successful on a micro level.

Since Jane's emotional struggles aren't rendered sharply enough to ever fully reveal her interior world, the character operates more like a catalyst for Daniel, causing him to vacillate between embracing the priesthood and abandoning his position for love. The relationships between Daniel and the fellow priests in his parish, Victor (Danny Glover) and Ollie (John C. McGinley), are thus left to pick up the slack, and to middling results. McGinley brings a relaxed, off-the-cuff humor to Ollie that feels lived-in, but his character's function is too limited; Ollie is little more than the sardonic, hip, and well-rounded priest who's meant to starkly contrast the traditionally ascetic vision of men of the cloth that Victor upholds. Together, Victor and Ollie are largely symbolicriffs on the shoulder-perched angel and devilone man giving Daniel the space to find his own way, the other constantly intervening to make certain he stays true to his commitment to the church.

The Good Catholic is admirable for its willingness to question the strict methodology of the church, but it still paints its characters, and specifically Daniel's crisis of faith, in very broad strokes. Shoulberg's failure to provide a compelling love story causes Daniel's decision to potentially leave his life's calling behind to feel particularly labored. And because Daniel carries his emotions so close to the vest, his seemingly torturous existential struggle remains as opaque and inscrutable as the reasons behind his burgeoning feelings for Jane. The film may succeed at expanding the boundaries of faith-based cinema, but it still feels obligatory in its approach.

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The Good Catholic - slantmagazine

Roy Moore claims he didn’t know about DACA because he ‘doesn’t speak the language of Washington’ – Washington Examiner

How much do you really need to know to serve in the Senate? The world's greatest deliberative body takes up complicated policy questions daily. Of course, there's going to be a learning curve, and senators have staff to aid in their decision-making.

On day one though, even the freshest senators should have a familiarity with the biggest political issues facing the nation. And that means Judge Roy Moore has some catching up to do.

Moore is currently the front-runner in a special Alabama Senate Republican primary runoff, and until recently he wasn't aware of the Deferred Action for Childhood Arrival program, let alone President Trump's long-standing promise to end a program that gives legal reprieve to hundreds of thousands of young illegal immigrants.

"Pardon?" Moore asked during a July WVNN local interview first unearthed by the Washington Examiner. "The Dreamer program?" After two more cringe-worthy minutes, Moore finally settles on agnosticism. Running for Senate in deep-red Alabama, the former state Supreme Court justice didn't come down one way or the other on a marquee immigration policy.

The judge was just lost in translation, campaign spokeswoman Katie Frost, tells the Washington Examiner. "Moore doesn't speak the language of Washington," she says clarifying her boss' position, "he speaks the language of the Constitution. Judge Moore opposes amnesty under any name."

According to Frost, the acronym is just "Washington-speak." If that's true, every radio shock jock, tea partier, and Republican north and south of the Mason-Dixon is fluent in swamp-speak. They've been railing against the program since former President Barack Obama bypassed Congress to create the program via executive order in 2012.

With three weeks ahead of the Sept. 26 primary, it's still too early to tell what Moore's gaffe might mean at the ballot box. Politics seems to eclipse more and more policy each day, so it's possible the Alabama Aleppo moment won't matter. Then again, Moore has positioned himself as an immigration hardliner, and he's running for Attorney General Jeff Sessions' old seat.

Sessions made a name for himself in the Senate as a Southern immigration hawk. It was the issue that catapulted him to prominence and sent him into Trump's orbit. More than embarrassing, Moore's ignorance on the marquee immigration issue has been picked up by everyone from the Associated Press to The Washington Post.

Moore's opponent, incumbent Sen. Luther Strange, quickly pounced on the blunder and reupped the former Alabama attorney general's past experience fighting the Obama administration in court.

"While career politician Roy Moore doesn't even know what DACA is," a campaign spokeswoman told the Washington Examiner, "Luther stands with President Trump, and has fought against Obama's illegal amnesty plan and won."

Regardless of who wins, whether Moore or Strange advances to the general election ballot, where they'll be heavily favored against a Democrat, they better get smart and fast.

Philip Wegmann is a commentary writer for the Washington Examiner.

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Roy Moore claims he didn't know about DACA because he 'doesn't speak the language of Washington' - Washington Examiner

Bioengineering could make more donor lungs suitable for transplant – Digital Trends


UPI.com
Bioengineering could make more donor lungs suitable for transplant
Digital Trends
With this mission in mind, researchers at Columbia University have developed a new method for bioengineering healthy lungs, which could have a major impact on the quantity of donor lungs that are suitable for transplants. Since currently only 20 ...
Researchers build first functional vascularized lung scaffoldUPI.com

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Higher ed Q&A: Stephen Knisley, bioengineering professor at NC A&T – Greensboro News & Record

GREENSBORO Shortly after he came to N.C. A&T, engineering professor Stephen Knisley noticed that the National Science Foundation had embarked on a groundbreaking project.

The NSF, the federal agency that supports research in science and engineering, wanted universities to look for different ways to teach engineering and computer science.

Intrigued, Knisley applied for a Revolutionizing Engineering Departments, or RED, grant. The NSF in June awarded him $2 million to fund a five-year project to improve A&Ts undergraduate engineering curriculum.

A professor and researcher who has devoted his career to working with cardiac devices, Knisley will lead a team that includes professors from A&Ts engineering, education and health and human sciences colleges.

News & Record higher education reporter John Newsom sat down with Knisley on Wednesday in McNair Hall, home of the biological, chemical and bioengineering department that Knisley chairs. The interview has been edited for length and clarity.

Q: Whats the goal of the RED project?

A: Its quite visionary. What (the NSF is) talking about will really change the way engineering is taught in the U.S. It will lead to a quantum increase in the competitiveness and talents and skills of our engineers, which will ultimately bleed over to economic competitivenessand competitivenessin all other areas of technology. ... The U.S. has always had a leading role (in engineering), but its a challenge to really keep up with all the other countries that are also doing well with their engineers.

Q: Whats the problem youre trying to solve?

A: Its motivation. I dont know why some students really do well in school and some dont. What I have to believe is for the most part is that engineering students are not achieving their full potential. I know some are getting close.

Our students in this department are some of the brightest ones who come to the university. I see some very high-performing, hard-working students who really are serious and they might be getting close to their potential. I see some who are getting by and are somewhere in between. Maybe theyre lacking motivation. We think maybe design activity would trigger those motivators.

Q: Design activity? What's that?

A: Design is a very integral part of engineering. . Engineers are doing things that apply their knowledge and skills to solve some problem and create some solution.

The way design is taught in most engineering programs that I've known is that it usually gets introduced to freshmen and then they go into coursework for a couple of years. Sophomores and juniors are doing engineering science and engineering analysis types of courses without much design. Then they come back in their senior year and do a very significant design project.

Theres a big gap in the middle where design isnt really emphasized ... The way it is now, (design is taught mostly) in the senior year, which really is maybe too late to really have the big impact on these students.

Q: Why do you think design is the key?

A: Part of the reasoning is based on some very compelling scientific literature that talks about why people want to learn things. (What) made the most sense to me was about certain features of the material that will become motivators to learn. One of those is value. If a student believes that what theyre about to learn has value, that will make them want to go in the class and learn it.

If youre working for an engineering firm thats making new bolts or something for companies that use them to manufacture lawn chairs or something like that, its hard to get the feeling for how youre impacting people with that.

But when youre creating a solution like this for people who have sore backs [motions behind him to a poster about a lumbar device designed by A&T students] you think, wow, if that works, then all these peoples grandmas and uncles are going to feel a lot better. Thats really a positive thing and they get real excited and they want to get up in the early in the morning and want to work late at night. Ive seen it time and time again because theres a social human impact piece in those disciplines.

What were doing now is looking at our curricula (in his department) and planning changes that were going to try to implement as soon as we can that will add design labs and design principles into the coursework for freshmen, sophomores, juniors and seniors.

One of the things were aiming to do is to decrease lecture content and add lab content where (students) can do these design activities, which will include hands-on activity. Some of that lab time is spent understanding the user and their need requirements looking at the market, looking at existing solutions, looking at gaps those solutions have. Its a similar process that entrepreneurs go through when they start a project.

Q: Why are you taking an entrepreneurial approach?

A: It emphasizes the need first and then the solution. What struck me about it was, of all the professors I had known over the years at universities, almost never does it happen that way, at least in my experience. The professors work in their lab and come up with a solution and sometimes theyre going after a need. After theyve discovered the molecule or the solution or the phenomena, then theyre saying, I wonder if this can be used for that problem or that problem or that problem? ...

The entrepreneurs never do that. They always have a need first looking for a solution. It was the flipping of an order. I thought that was kind of revolutionary, just that whole concept. Thats basically the way were doing our design now need first, then the solution.

Q: So if it works?

A: A lot of this is revolutionary stuff. If it works the way we think, its going to be steering us in a better direction toward producing more highly competitive engineers.

Contact John Newsom at (336) 373-7312 and follow @JohnNewsomNR on Twitter.

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Higher ed Q&A: Stephen Knisley, bioengineering professor at NC A&T - Greensboro News & Record