AI singularity may come in 2027 with artificial ‘super intelligence’ sooner than we think, says top scientist – Livescience.com

Humanity could create an artificial intelligence (AI) agent that is just as smart as humans in as soon as the next three years, a leading scientist has claimed.

Ben Goertzel, a computer scientist and CEO of SingularityNET, made the claim during the closing remarks at the Beneficial AGI Summit 2024 on March 1 in Panama City, Panama. He is known as the "father of AGI" after helping to popularize the term artificial general intelligence (AGI) in the early 2000s.

The best AI systems in deployment today are considered "narrow AI" because they may be more capable than humans in one area, based on training data, but can't outperform humans more generally. These narrow AI systems, which range from machine learning algorithms to large language models (LLMs) like ChatGPT, struggle to reason like humans and understand context.

However, Goertzel noted AI research is entering a period of exponential growth, and the evidence suggests that artificial general intelligence (AGI) where AI becomes just as capable as humans across several areas independent of the original training data is within reach. This hypothetical point in AI development is known as the "singularity."

Goertzel suggested 2029 or 2030 could be the likeliest years when humanity will build the first AGI agent, but that it could happen as early as 2027.

Related: Artificial general intelligence when AI becomes more capable than humans is just moments away, Meta's Mark Zuckerberg declares

If such an agent is designed to have access to and rewrite its own code, it could then very quickly evolve into an artificial super intelligence (ASI) which Goertzel loosely defined as an AI that has the cognitive and computing power of all of human civilization combined.

"No one has created human-level artificial general intelligence yet; nobody has a solid knowledge of when we're going to get there. I mean, there are known unknowns and probably unknown unknowns. On the other hand, to me it seems quite plausible we could get to human-level AGI within, let's say, the next three to eight years," Goertzel said.

He pointed to "three lines of converging evidence" to support his thesis. The first is modeling by computer scientist Ray Kurzweil in the book "The Singularity is Near" (Viking USA, 2005), which has been refined in his forthcoming book "The Singularity is Nearer" (Bodley Head, June 2024). In his book, Kurzweil built predictive models that suggest AGI will be achievable in 2029, largely centering on the exponential nature of technological growth in other fields.

Goertzel also pointed to improvements made to LLMs within a few years, which have "woken up so much of the world to the potential of AI." He clarified LLMs in themselves will not lead to AGI because the way they show knowledge doesn't represent genuine understanding, but that LLMs may be one component in a broad set of interconnected architectures.

The third piece of evidence, Goertzel said, lay in his work building such an infrastructure, which he has called "OpenCog Hyperon," as well as associated software systems and a forthcoming AGI programming language, dubbed "MeTTa," to support it.

OpenCog Hyperon is a form of AI infrastructure that involves stitching together existing and new AI paradigms, including LLMs as one component. The hypothetical endpoint is a large-scale distributed network of AI systems based on different architectures that each help to represent different elements of human cognition from content generation to reasoning.

Such an approach is a model other AI researchers have backed, including Databricks CTO Matei Zaharia in a blog post he co-authored on Feb. 18 on the Berkeley Artificial Intelligence Research (BAIR) website.

Goertzel admitted, however, that he "could be wrong" and that we may need a "quantum computer with a million qubits or something."

"My own view is once you get to human-level AGI, within a few years you could get a radically superhuman AGI unless the AGI threatens to throttle its own development out of its own conservatism," Goertzel added. "I think once an AGI can introspect its own mind, then it can do engineering and science at a human or superhuman level. It should be able to make a smarter AGI, then an even smarter AGI, then an intelligence explosion. That may lead to an increase in the exponential rate beyond even what Ray [Kurzweil] thought."

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AI singularity may come in 2027 with artificial 'super intelligence' sooner than we think, says top scientist - Livescience.com

The Singularity When We Merge With AI Won’t Happen – Walter Bradley Center for Natural and Artificial Intelligence

Erik J. Larson, who writes about AI here at Mind Matters News, spoke with EP podcast host Jesse Wright earlier this week about the famed/claimed Singularity, among other things. Thats when human and machine supposedly merge into a Super Humachine (?).

Inventor and futurist Ray Kurzweil has been prophesying that for years. But philosopher and computer scientist Larson, author of The Myth of Artificial Intelligence (Harvard 2021), says not so fast.

The podcast below is nearly an hour long but it is handily divided into segments, a virtual Table of Contents. Weve set it at The Fallacy of the Singularity, with selections from the transcript below. But you can click and enjoy the other parts at your convenience.

00:00 Intro 01:10 Misconceptions about AI Progress

 11:48 Bias and Misinformation in AI Models

21:52 The Plateau of Progress & End of Moore’s Law

31:30 The Fallacy of the Singularity

47:27 Preparing for the Future Job Market

Note: Larson blogs at Colligo, if you wish to follow his work.

And now

Decades ago, Larson says, programmers were focused on getting computers to win at complex board games like chess. One outcome was that their model of the human mind was the computer. And that, he says, became a narrative in our culture.

Larson: [33:19] You know, people are kind of just bad versions of computers. If you look at all the literature coming out of psychology and cognitive science and these kind of fields, theyre always pointing out how were full of bias jumping to the wrong conclusions. We cant be trusted. Our brains are very very Yesterdays Tech so to speak.

Choking off innovation?

Larson sees this easy equation of the mind and the computer as choking off innovation, at which humans excel. It encourages people to believe that computers will solve our problems when there are major gaps in their ability to do so. One outcome is that contrary to clich this one of the least innovative periods in a while.

Larson: [34:25] The last decade is one of the least innovative times that weve had in a long time and its sort of dangerous that everybody thinks the opposite. If people said, wait a minute, were just doing tweaks to neural networks; were just doing extensions to existing technology Yes, were making progress but were doing it at the expense of massive amounts of funding, massive amounts of energy consumption, right?

Instead he sees conformity everywhere, accompanied by a tendency to assume that incremental improvements amount to progress in fundamental understanding.

So how does our self-contented mediocrity produce an imminent, unhinged Singularity?

Well, a pinch of magic helps!

Larson: [37:49] Whats underlying that is this idea that once you get smart enough, you also become alive. And thats just not true. A calculator is extremely good at arithmetic. No one can beat a calculator on the face of the planet but that doesnt mean that your calculator has feelings about how its treated. In a sense, theres just a huge glaring error philosophical error thats being made by the Superintelligence folks, the existential risk folks. Thats wasted energy in my view. Thats not whats going to happen.

If a more powerful computer is not like a human mind, whats really going to happen?

Larson: [38:40] Very bad actors are going to use very powerful machines to screw everything up Somebody gets control of these systems and directs them towards ruining Wall Street, ruining the markets, bringing down the power grid. Thats a big threat. The machines themselves I would bet the farm that theyre not going to make the leap from being faster and calculating more complicated problems to being alive in any sort of sense or having any kind of motivations or something that could misalign like that. Thats the Sci-Fi Vibe thats getting pushed into a scientific discussion.

The Singularity depends on a machine model of the mind

Larson: [46:17] If were just a complicated machine, then it stands to reason that at some point well have a more complicated machine. Its just a continuum and were on that. But if you actually remove that premise and say, look were not machines, were not computers then you have an ability to talk about human culture in a way that can actually be healthy. We think differently, we reason differently, we have superior aspects to our behavior and performance, and we actually do care and have motivations about how things turn out unlike the tools we use.

So it looks as though the transhuman could go extinct without ever existing.

You may also wish to read: Tech pioneer Ray Kurzweil: We will merge with computers by 2045. For computers, Even the very best human is just another notch to pass, he told the COSM Technology Summit. Kurzweil explained, To do that, we need to go inside your brain. When we get to the 2030s, we will be able to do that. So a lot of our thinking will be inside the cloud. In another ten years, our non-biological thinking will be much better than our biological thinking. In 2017, he predicted 2045 for a total merger between man and machine.

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The Singularity When We Merge With AI Won't Happen - Walter Bradley Center for Natural and Artificial Intelligence

The Singularity is Nearer | Daniel S. Smith | The Blogs – The Times of Israel

Review of Ray Kurzweils forthcoming (June 2024) book The Singularity is Nearer: When We Merge with AI. Penguin Publishing Group.

Renowned futurist Ray Kurzweil envisions a future where those under eighty and in good health have the potential to live forever. He predicts that by the 2030s, we will be able to extend the neocortex of our brains into the cloud, enabling a massive increase in human intelligence. Kurzweils latest work, The Singularity is Nearer, takes readers on a journey from ignorance to enlightenment, shedding light on the incredible possibilities that await us. Even if youve previously overlooked Kurzweils predictions over the past four decades, now is the time to take notice. His track record of accurate forecasts demonstrates that we can indeed predict the future, and his insights into what lies ahead are invaluable.

Many who would have brushed Kurzweil aside as a heretic in 2005 when he published the Singularity is Near, reviving John the Baptists prediction, the kingdom of heaven is near (Matthew 3:2), in 1990 the Age of Intelligent Machines, or 1999 Age of Spiritual Machines, are more likely to take his arguments seriously in 2024. Incredible advancements in technology over the past few decades, particularly in the fields of AI and biotech, have lent significant credibility to Kurzweils predictions. Microsoft co-founder Bill Gates describes Kurzweil as, the best person I know at predicting the future of artificial intelligence.

Kurzweil is intervening into a century of literature and debate, right up to spring of 2023. He has been working in the field of artificial intelligence, a termhe does not like because it makes it seem less real,for over sixty years. The book serves as a historiography of machine intelligence and the myriad debates therein.

In 1950 Alan Turing asked Can machines think? Pioneering computer scientist John Von Neumann made the first reference to the Singularity, writing a few years after Turing: the ever-accelerating progress of technology would yield some essential singularity in the history of the race. In 1956, John McCarthy defined AI as getting a computer to do things which, when done by people, are said to involve intelligence. In 1965, British Mathematician Irving John Good predicted an impending intelligence explosion. In that same year, Herbert Simon, a scientist who co-founded the field of artificial intelligence, forecasted by 1985, machines will be capable of doing any work a man can do. In 1993, Vernor Vinge wrote his seminal essay: The Coming Technological Singularity: How to Survive in the Post-Human Era, arguing: Within thirty years, we will have the technological means to create superhuman intelligence. Shortly after, the human era will be ended.

In his 2005 book The Singularity is Near, Kurzweil defines the singularity as an expansion of human intelligence by a factor of trillions through merger with its nonbiological form. This will happen so rapidly that life will be irreversibly transformed. In The Singularity is Nearer, Kurzweil predicts in 2045 humanity will be, Freed from the enclosure of our skulls, and processing on a substrate millions of times faster than biological tissue, our minds will be free to grow exponentially, ultimately expanding our intelligence millions-fold. This is the core of my definition of the Singularity. The laws of physics, allow for a continuation of exponential growth until non biological intelligence is trillions of times more powerful than all of human civilization today, contemporary computers included. This intelligence will be too much for planet earth, and therefore engulf the entire universe.

Critics of Kurzweil such as Microsoft co-founder Paul Allen & Mark Greaves of Schmidt Futures describe his claims as premature. Oren Etzioni, CEO of the Allen Institute for Artificial Intelligence, is also doubtful about the imminence of superhuman AI: Exponentials are very important. If we extrapolate exponentials, we can be exponentially wrong. Mathematician Roger Penrose argued in his 1989 book the Emperors New Mind that some facets of human thinking can never be emulated by a machine. Philosopher John Searle has also argued against humanity achieving machine sapience, whereas engineer and the godfather of nanotechnology Noam Chomsky thinks the singularity is science fiction. Philosopher Hubert Dreyfus said that AI is impossible in a 1965 RAND corporate memo entitled Alchemy and Artificial Intelligence, in which he concluded that the ultimate goals of AI research were as unachievable as were those of alchemy. The computer scientist Joseph Weizenbaum described the idea as obscene, anti-human and immoral. Pulitzer Prize winner Douglas Hofstadter considered it over-promising. Virtual-Reality (VR) pioneer Jaron Lanier emphasizes the importance of preserving individual creativity and personal expression in the digital age, warning against the homogenization of human experiences through technology.

How couples meet. Courtesy: Statista

Yet Kurzweil is doubling down again, arguing the rate of change is itself accelerating. He notes that today 39 percent of couples have met online. Who would have believed this in 2005?

In 2005, we were in the fourth epoch of technological development. According to Kurzweil, we are expected to pass the Turing Test by 2029, marking the transition to the fifth epoch. This prediction was first introduced in his 1999 book The Age of Spiritual Machines.

As we enter the 2030s, the fifth epoch will be characterized by a significant expansion of our cognitive abilities. This will be achieved by connecting the neocortex of our brain to the cloud, a concept Kurzweil explored in his 2012 book How to Create a Mind. For the sixth epoch, provided we are not limited by the speed of light, we can fill the entire universe with our intelligence by the year 2200. His predictions are based on his analysis of exponential growth in technological advancements.

In his 1990 book The Age of Intelligent Machines, Kurzweil predicted: A computer will defeat the human world chess champion around 1998, and well think less of chess as a result. He was one year off, as DeepBlue defeated chessmaster Garry Kasparov in 1997. In 2015, AlphaGo, an AI developed by Googles DeepMind, defeated the European Go champion Fan Hui. This victory marked the first time an AI had beaten a human professional Go player on a full-sized board without a handicap. With all of this progress, why would Kurzweil back down now?

Kurzweil argues AI will not be our competitor, but rather an extension of ourselves.The fifth epoch will involve brain-computer interfaces and will take seconds to minutes (for us) to explore ideas unimaginable to present-day humans. This will benefit humankind, compared to life hundreds of years ago which was, labor-intensive, poverty filled, and disease and disaster prone.

Life is getting exponentially better, yet we hardly notice because the news media tends to amplify tragedies as opposed to steady improvement. Constant fear mongering which plays toward our primal instincts leads to a more pessimistic view of society, for,its easier to share videos of disaster, but gradual progress doesnt generate dramatic footageThis crowds out our capacity to assess positive developments that unfold slowly.

Kurzweil is a techology optimist who takes a historical exponential as opposed to an intuitive linear view of human progress. Linear growth is steady; exponential growth becomes explosive, for we wont experience one hundred years of technological advance in the twenty-first century; we will witness on the order of twenty thousand years of progress. He claims Moores Law has nothing to do with Intel and Thomas Moore, and has in fact been occurring since the 1880s, for, It was the fifth, not the first, paradigm to bring exponential growth to the price/performance of computing.

His optimism set off a debate with Bill Joy of Sun Microsystems whose famous 2000 Wired magazine essay, Why the Future Doesnt Need Us, is more pessimistic. This is part of a larger divide with folks like Elon Musk and Stephen Hawking on the potential perils of artificial general intelligence (AGI). Ethicist and founder of the Machine Intelligence Research Institute (MIRI) Eliezer Yudkowsky argues the only way to deal with the threat of AGI is to shut it all down. Yudkowsky predicts, If somebody builds a too-powerful AI, under present conditions, I expect that every single member of the human species and all biological life on Earth dies shortly thereafter. He predicts a hard takeoff versus Robin Hansons soft takeoff. Kurzweil says he falls somewhere in the middle.

Citing Steven Pinkers 2011 book Better Angels of Our Nature and 2018 book Enlightenment Now, as well as Peter Diamandis and Steven Kotlers 2012 book Abundance, Kurzweil believes the state of the world keeps improving. He uses fifty graphs to show gradual progress over the past century, such as a decline in the rates of poverty, violence and child labor. He expects AI to accelerate these trends. Other optimists include OpenAI CEO Sam Altman who argues: A.I. will be the greatest force for economic empowerment and a lot of people getting rich we have ever seen.

Courtesy: Cambridge University Press

In the technological pessimists most extreme expression, Ted Kacyznki, the unabomber, called, violently, for an anti-tech revolution. Kurzweil wrote in the Age of Spiritual Machines:

Kaczynski is not talking about a contemplative visit to a nineteenth-century Walden Pond, but about the species dropping all of its technology and reverting to a simpler time. Although he makes a compelling case for the dangers and damages that have accompanied industrialization his proposed vision is neither compelling nor feasible. After all, there is too little nature left to return to, and there are too many human beings. For better or worse, were stuck with technology.

Steven Pinker notes: Pessimism can be a self-fulfilling prophecy, so it is best we accept the inevitable and make the most of it. Yuval Harari writes, In the twenty-first century, those who ride the train of progress will acquire divine abilities of creation and destruction, while those left behind will face extinction. Kurzweil says the nonbiological part of our intelligence will combine the pattern-recognition powers of human intelligence with the memory- and skill-sharing ability and memory accuracy of machines, and thus will make it far more powerful than biological intelligence.

Kurzweil argued in The Singularity is Near: any significant derailment of the overall advancement of technology is unlikely. Even epochal events such as two world wars (in which on the order of one hundred million people died), the cold war, and numerous economic, cultural, and social upheavals have failed to make the slightest dent in the pace of technology trends. Over the past two centuries, technological advancements have created a positive feedback loop, leading to improvements in various aspects of human well-being, Our merger with our technology has aspects of a slippery slope, but one that slides up toward greater promise, not down into Nietzches abyss. This will continue, as nanobots may reverse pollution from earlier industrialization.

For example, there has been a rise in the percentage of homes with electricity and computers, a proliferation in the availability of radios and televisions, an increase in life expectancy, and a rise in US GDP per capita. However, as Senator Robert F. Kennedy famously stated, GDP measures everything except that which is worthwhile, suggesting that while these advancements have certainly improved certain aspects of human life, they may not necessarily reflect a holistic view of well-being.

Yuval Harari notes suicide has gone up in industrialized countries, it is an ominous sign that despite higher prosperity, comfort and security, the rate of suicide in the developed world is also much higher than in traditional societies. South Korea has rapidly industrialized since 1985, yet the suicide rate in that same period increased fourfold. Wealthy nations like Switzerland and Japan have more than twice as many suicides per capita than Peru and Ghana. Harari argues this may be because, We dont become satisfied by leading a peaceful and prosperous existence. Rather, we become satisfied when reality matches our expectations. The bad news is that as conditions improve, expectations balloon. Could life extension technologies could potentially help reduce the rates of suicide by giving people more hope for the future?

Some could be forgiven for wondering whether technological advancement has really benefited society. Do students with smartphones, tablets and computers learn better than if they only had a few books, a teacher, a notepad, and a pencil? What about the mental health problems posed by social media?

Writers like Adam Garfinkle, David Brooks and George Will are concerned we have forgotten how to dwell with a text. Yuval Harari does not own a smartphone, for he believes it is impossible to have perspective if you are constantly scrolling. He meditates for two hours a day, and takes month out of each year to go on a silent retreat with no electronics. Of course most of us are not so lucky and are forced to use these technologies, whereas Hararis husband, Itzik Yahav, who Yuval describes as his internet of all things, manages his work. The increasing integration of technology into our lives has been proven to lessen empathy, and the drawbacks paired with the benefits are the paradox at the heart of the book, for one of Kurzweils principles is the respect for human consciousness.

As one indicator of progress, Kurzweil shows that democracy has spread rapidly around the world over the past century. Sure, the right to vote has been extended. But how much do our votes matter if the algorithm knows us better than we know ourselves, and can manipulate us, as the 2016 Cambridge Analytica Scandal showed? Brain scanners can now predict our actions and desires before we are aware of them. Yuval Harari notes: Whats the point of having democratic elections when the algorithms know not only how each person is going to vote, but also the underlying neurological reasons why one person votes Democrat while another votes Republican? Harari continues:

Artificial intelligence and biotechnology might soon overhaul our societies and economies and our bodies and minds too but they are hardly a blip on the current political radar. Present-day democratic structures just cannot collect and process the relevant data fast enough, and most voters dont understand biology and cybernetic well enough to form any pertinent opinions. Hence traditional democratic politics is losing control of events, and is failing to prevent us with meaningful visions of the future.

Kurzweil doubts our political system will have evolved to answer these questions by the time AI passes the Turing Test, which is why we should push candidates to talk more about AI now so we are better able to manage it.

Kurzweils ultimate goal is to show the benefits outweigh the costs, urging: Careful use of AI to provide openness and transparency while minimizing its potential to be used for authoritarian surveillance or to spread disinformation. Combining his pattern recognition theory of mind (PRTM) with the LOAR will allow us to vastly extend our intelligence, and hopefully think of ways to avert the worst before it happens. This is quite the gamble, for he warns the same technologies that could empower us to cure cancer could be used by terrorists to unleash a deadly bioweapon.

A clear example of the benefits outweighing the costs are technological advancement for people with disabilities, who have seen vast improvements in their quality of life. As an inventor, Kurzweils advancements in speech recognition have led to the development of assistive technologies that help people with disabilities perform tasks that might otherwise be impossible, such as communicating, accessing information, and controlling devices. Kurzweil has proposed the idea of using brain-computer interfaces (BCIs) to allow people with paralysis or other disabilities to control computers and other devices using their brainwaves. Life extension could lead to breakthroughs in treating diseases and conditions that disproportionately affect people with disabilities.

The author is not concerned about technological inequality. He cites smartphones as a case in point. At first, perhaps only the super-rich had access, but within years they became so cheap to mass-produce that now practically everybody has one. The same is true with vaccines. In his 2014 book Superintelligence, Oxford University philosopher Nick Bostrom argues social elites will gain first access to biological enhancement mechanisms and inspire a culture shift among everybody else: Many of the initially reluctant might join the bandwagon in order to have a child that is not at a disadvantage relative to the enhanced children of their friends and colleagues. A domino effect will ensure, assuming everybody can access these therapies.

Yuval Harari disagrees. He writes that in the 20th century medicine aimed to heal the sick, whereas in the twenty-first century medicine will increasingly aim to upgrade the healthy. There is hardly any reason to believe this will benefit the masses the same as elites, for

The age of masses may be over, and with it the age of mass medicine. As human soldiers and workers give way to algorithms, at least some elites may conclude there is no point in providing improved or even standard levels of health for masses of useless poor people, and it is far more sensible to focus on upgrading a handful of superhumans beyond the norm..Unlike in the twentieth century, when the elite had a state in fixing the problems of the poor because they were militarily and economically vital, in the twenty-first century the most efficient (albeit ruthless) strategy might be to let go of the useless third-class carriages, and dash forward with the first class only.

The concern is that the elites may find the populace superfluous given the rise of nonhuman intelligence, and therefore take the attitude of Marie Antionette and let them eat cake.

Hararis opinion is worth urgently considering, for Kurzwiel says we are entering the steep part of the exponential. Eliezer Yudkowsky argues in his 1996 book Staring Into the Singularity: Dont describe Life after Singularity in glowing terms. Dont describe it at all. But Kurzweil does not see the merger of humans and machines as something indescribable, but rather something that is already happening. Our intelligence is augmented exponentially by our constant access to smartphones, which is unprecedented because humans and machines are making decisions together.

In the Enlightenment, Rene Descartes said, Cogito ergo sum, or I think, therefore I am. Alan Turing helped set off the field of machine intelligence by asking can machines think? Yuval Harari argues intelligence is decoupling from consciousness, the difference being, Intelligence is the ability to solve problems. Consciousness is the ability to feel things, such as pain, joy, love, and anger.

In the 18th century, John Locke wrote: Since it is the understanding, that sets man above the rest of sensible beings, and gives him all the advantage and dominion, which he has over them; it is certainly a subject, even for its nobleness, worth our labour to inquire into.John Searle argued consciousness could be infused into machines: So the first step is to figure out how the brain does it and then build an artificial machine that has an equally effective mechanism for causing consciousness. Kurzweil believes: In this view a dog is also conscious but somewhat less than a human. An ant has some level of consciousness, too, but much less that of a dog. The ant colony, on the other hand, could be considered to have a higher level of consciousness than the individual ant; it is certainly more intelligent than a lone ant. It matters whether or not machines are conscious, for it is on this basis that we can decide whether or not they should have rights.

Max Tegmark of the Future of Life Institute defines consciousness as subjective experience. The 2018 Cambridge Declaration of Consciousness concluded that consciousness is not exclusive to humans. In the future, it may be possible to transfer consciousness from our brains to computers. By augmenting the neocortex, we can enhance our subjective consciousness, experiencing the world in new ways. Kurzweil envisions, Well be able to send nanobots into the brain noninvasively through the capillaries, bypassing invasive procedures. This would mark the first significant neocortex revolution since the last one two million years ago, potentially enabling us to expand our intelligence a million-fold. In Kurzweils view, those who embrace this augmentation will far surpass those with unaugmented biological brains, leading to an unprecedented cognitive leap forward.

The good news is we will be able to back our brains up to the cloud, just like we do with our documents in Microsoft Office, so our experiences and records will be preserved regardless of what befalls our brain. We will also be able to download new skills in an instant. By the 2030s, we will be able to bring dead loved ones back using all of their data. A recent political attack-ad levied by the super-pac The Lincoln Project recreates US presidential candidate Donald Trumps late father, Fred Trump, disparaging his son. Who is to say which replicants can and cannot be created? By the early 2040s, us mere humans would not be able to tell the difference between our partner and a clone. Kurzweil collected all of his late father, Frederic Kurzweils writings and created a Dad Bot, and is planning on replicating himself. We can only hope this means he will never stop writing, if that is still something humans do in the future.

The Singularitys impact on the economy will be highly disruptive, shifting the focus from deskilling and upskilling to nonskilling. This transition is unique compared to previous industrial revolutions, as the emphasis on education has grown alongside labor productivity. Yet Kurzweil does not believe we are in competition with AI. Despite these challenges, employment has grown from 31% to 48% of the population, with per capita GNP increasing by 600% in constant dollars.

Courtesy: ILO

These trends are supported by research, such as Carl Benedikt Frey and Michael Osbornes 2013 paper and Erik Brynjolfsson and Andrew McAfee in his 2014 book The Second Machine Age, both of which show, to varying degrees, that technology will both eliminate and create jobs. With coding already on the decline, its essential to adapt to these shifts in the job market and economic landscape. The US had a 45 percent poverty rate in 1870, down to 11.5 percent in 2020. Henrik Ekelund, Founder & Chairman of BTS Group, wrote in a recent World Economic Forum (WEF) Agenda article that concerns today about a jobless future will be just as wrong as earlier concerns.

Yet the bigger question is not whether there will be jobs in the future, but rather how to manage the transition. Kurzweil writes: Although it will be technologically and economically possible for everyone to enjoy a standard of living that is high by todays measures, whether we actually provide this support to everyone who needs it will be a political decision.if we are not careful as a society, toxic politics could interfere with rising living standards.

Social protection spending in the US has been on the rise, though some argue that current levels are still inadequate. However, as AI continues to drive down the costs of medicine, food, and housing, its possible that the percentage of GDP devoted to social safety nets may not need to increase significantly. Nevertheless, Daniel Kahneman cautions that the transition may be marked by conflict and violence.

Grand theories on global net job creation offer little comfort to those living paycheck to paycheck and facing job loss due to AI. The COVID-19 pandemic prompted a basic-income pilot program in the US, with enhanced unemployment benefits, business support, and direct stimulus checks. Just as workers were supported during the pandemic, those who lose jobs due to technological change should be assisted. If progress is for the greater good, the burden of sacrifice should be shared by all, especially those who stand to gain financially, rather than solely by those who lose their jobs.

Kurzweil claims that increasing education has helped us adapt to technological change over the past two centuries. When we merge with non-biological intelligence, reskilling and upskilling will become effortless, as machines can instantly transfer skills to one another through the cloud. Our enhanced neocortex will allow us to download skills instantly, and our intelligence will be digitally backed up. Although uploading isnt expected until the 2040s, Kurzweil suggests keeping written records. In The Age of Spiritual Machines, he predicted a 2099 Destroy-all-copies movement, enabling individuals to delete their mind file and all backups, raising questions about the control and ownership of digital consciousness.

He foresees an age of abundance where advances in information technology make essential goods and services increasingly affordable. Food and clothing are becoming information technologies, the former reducing violence upon animals. 3D printing is set to revolutionize manufacturing by shifting the paradigm from centralized to decentralized production. This transformation extends beyond traditional manufacturing and into the realm of biology, enabling the printing of entire organs and even buildings, which could solve homelessness. 3D printing technology is becoming more accessible to non-experts, and is now available at hundreds of UPS locations. In the 2030s, advanced nanomanufacturing will enable the production of nearly anything for mere pennies per pound, thanks to the relentless march of miniaturization.

The main concern for Kurzweil is finding purpose & meaning in a world where many will not have to work if they do not want to. Kurzweils mentor, Marvin Minsky, commented that he does not think this will be a problem, as even now folks are easily entertained sitting in a stadium and watching men play football. Such experiences will be enhanced, for, when we digitally augment our neocortex starting sometime in the 2030s, we will be able to create meaningful expressions that we cannot imagine or understand today. Thanks to AR and VR we will have not just life extension but also radical life enhancement. In his book Extend he argues, Extending life will also mean vastly improving it.

There is also the challenge of trust: its not hard to see how exaggerated fears of secret genetic manipulation or government-controlled nanobots could cause people in 2030 or 2050 to reject crucial treatments. What Kuzweil describes as fundamentalist humanism will be overcome because demand for therapies will be irresistible.

Kurzweil believes death is a tragedy we rationalize away. He writes: When we lose that person, we literally lose part of ourselves. This is not just a metaphorall of the vast pattern recognizers that are filled with the patterns reflecting the person we love suddenly change their nature. Although they can be considered a precious way to keep that person alive within ourselves, the vast neocortical patterns of a lost loved one turn suddenly from triggers of delight to triggers of mourning. He is not willing to accept it. The promise of the Singularity is to liberate us from our limitations. By extending our lifespan, we can not only live longer but also improve our quality of life, reducing the risk of age-related diseases and enhancing our overall well-being.

Building upon the ideas presented in his book Transcend, we are now entering the second phase of this journey, which involves merging biotechnology with AI. In the 2030s, we will enter a new phase, with nanobots repairing our organs and enabling us to live beyond 120 years. He believes, We are going to accelerate the extension of our lifespan starting in the 2020s, so if you are in good health and younger than eighty, this will likely happen in your lifetime. When we begin to utilize all of the earths resources, we will find they are a thousand times greater than we need, so overpopulation is not a concern.

The ultimate goal is to put our destiny in our own hands, rather than leaving it to fate, allowing us to live as long as we desire. AI has already demonstrated its potential in improving the speed and quality of COVID-19 vaccines and in computer-aided drug discovery. It also has the potential to target mental health problems at their root cause. As someone who takes many supplements and expects to be no older than 40 when the Singularity arrives, Kurzweil embodies the optimism and forward-thinking that characterizes this movement towards a new era of human potential. In The Singularity is Near, he writes: Another error that prognosticators make is to consider the transformations that will result from a single trend in todays world as if nothing else will change. A good example is the concern that radical life extension will result in overpopulation and the exhaustion of limited material resources to sustain human life, which ignores comparably radical wealth creation from nanotechnology and strong AI.

Kurzweils optimism in his books contrasts with declining reading habits. While he argues life is improving exponentially, areas like news may not have improved with the shift to digital formats. Kurzweil should address potential downsides, such as shortened attention spans and changing priorities among younger generations. Despite unprecedented access to education, many people choose less intellectually stimulating activities, raising concerns about technologys impact on learning and growth.

The Singularity is Nearer is both a historiography of Kurzweils work and the field of AI, as well as a significant historical document due to Kurzweils firsthand experiences. The book should catalyze further exploration of human-machine integration and its implications. Kurzweils credibility stems from his visionary ideas, once considered outlandish, that have gained traction over time. Although the book covers advanced concepts, its accessibility to the general reader is crucial for fostering a broader societal discussion. Its important for citizens and politicians alike to engage in these conversations and address the ethical, political, legal, and social questions that arise. By doing so, we can proactively manage the development and integration of these transformative technologies.

If we cannot change the future, there is no point in talking about it. Kurzweil is right that the merger between human and machine intelligence is not just inevitable, but already happening. The question, then, is will we have a world akin to Aldous Huxleys Brave New World, or one in which we use technology to greatly reduce suffering and increase human potential? A 1903 quote by George Bernard Shaw best sums up Ray Kurzweil, The reasonable man adapts himself to the world; the unreasonable one persists in trying to adapt the world to himself. Therefore all progress rests on the unreasonable man.

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The Singularity is Nearer | Daniel S. Smith | The Blogs - The Times of Israel

NJIT Chemist wins Wallace H. Coulter Award for Career Achievements – EurekAlert

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NJITs Wunmi Sadik takes center stage as the honored keynote speaker at the 75th annual Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy.

Credit: Ricky Haldis Photography

NJIT Distinguished Professor of Chemistry Wunmi Sadik has recently been honored with the prestigious Wallace H. Coulter Lectureship during a guest appearance at one of the largest scientific conferences on laboratory science in the world, Pittcon.

The Wallace H. Coulter Lectureship is presented each year at Pittcon to an outstanding individual who has demonstrated a lifetime commitment to, and made important contributions that have had a significant impact on education, practice and/or research in laboratory science.

Sadik, chair ofNJIT's Department of Chemistry and Environmental Sciences,was recognized for leadership and scientific breakthroughs spanning a 30-year career that began as a researcher with the Environmental Protection Agency in 1994.

Shes noted for contributing to advancements in the fields of nanomaterials, green chemistry and sustainability, while sparking innovation in analytical sensor technologies used for the detection of everything from drugs and explosives to human disease and environmental contamination.

The award included a $10,000 honorarium and a spot as featured guest speaker atthis year's Pittcon in San Diegoheld Feb. 24-28, which drew nearly 30,000 attendees.

This award is hugely significant to me on a personal and professional level, Sadik toldPittcon Todayahead of her appearance. On a professional level, I have attended Pittcon for the last 30 years and have witnessed leaders in the field deliver the Coulter Lecture many times. It is gratifying to be recognized along with these outstanding leaders in Analytical Chemistry for my work and career thus far.

On a personal level, my family and I attended Pittcon many years ago together several times. My children always looked forward to getting their pictures taken at the Pittcon Souvenir stand and receiving their Future Scientist badges. As adult professionals, they will watch me receive the Coulter Award. It is a privilege to see how Pittcon has influenced their careers in chemistry and medicine, law and private equity, and economics and computer science.

Sadiks Pittcon presentation addressed the potential of bridging nanoscience and sustainability to improve healthcare and the environment. The topic has been a career focus for Sadik which led her to co-found theSustainable Nanotechnology Organization a nonprofit dedicated to the responsible use of nanotechnologies around the world.

Her plenary lecture, titled Sustainable Nanomaterials for Sensing Human Health and the Environment, highlighted a range of applications for nanomaterials shes been developing as director ofNJITs BioSMART Center.

Sadik's latest efforts at NJIT have includednano-sized biosensors for measuring pain biomarkers in human bloodthat could allow clinicians to objectively measure pain experienced by their patients. Shes also recently contributed to cutting-edge approaches for rapidly detecting anddegrading toxic PFAS chemicals(per- and polyfluoroalkyl substances) in the environment.

The Wallace H. Coulter Lectureship is the latest career milestone for Sadik, who earned notable distinction in the field of chemistry in 2023 when she was named fellow by the American Chemical Society.

Sadik is also a fellow of the American Institute of Medical and Biological Engineering, The National Academy of Inventors, and the Royal Society of Chemistry, and has published over 200 peer-reviewed works with 400 invited lectures and conference contributions to date. She holds 12 U.S. patents and patent applications and is the founder of three startup companies.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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Why the Oil and Chemical Lobby Is Taking Aim at New York’s Plastic Waste Bill – DeSmog

A version of this piece was originally published by ExxonKnews.

Last week at the New York State Capitol, more than 300 advocates joined lawmakers for a rally to urge the passage of a landmark waste reduction bill that proponents say is the best piece of legislation in the country aimed at lessening plastic trash. The bill is gaining fast momentum but lobbyists for major oil and chemical companies want to make sure it doesnt cross the finish line.

The Packaging Reduction and Recycling Infrastructure Act would dramatically cut the amount and toxicity of plastic garbage New Yorkers throw away by targeting the source. It would reduce plastic packaging in New York by half over the next 12 years, and it would prevent a slew of toxic chemicals from being used in those materials. Notably, it would also shift the cost of managing plastic waste from municipal governments and taxpayers to the companies that produce it including oil majors like ExxonMobil, Chevron, and Shell.

The American Chemistry Council (ACC), a trade association for those same chemical and plastic producers, is hoping to prevent that from happening. The ACC isfighting to weaken the bill, which it claims is overly restrictive in its definitions of toxic substances and recycling. Its major gripe: the legislation would not allow for chemical or advanced recycling, a process that would use heat and chemicals to break down plastic waste and supposedly turn it into new plastic.

This is not just about enforcement; its about creating a more sustainable future where economic and environmental interests are aligned, wrote Craig Cookson, senior director of plastics sustainability at the ACC, in a Januaryop-edfor the Albany Times-Union. A good EPR [Extended Producer Responsibility] bill will not only support New Yorks mechanical recycling infrastructure; it would also allow for innovation, including science-based advanced recycling solutions.

Yet experts and advocatesagreethat chemical recycling doesnt work, and when it does, is mostly used to createmore fossil fuels to be burned. Proponents of New Yorks bill, like Beyond Plastics director and former EPA administrator Judith Enck, say the industry is teeing up a false solution to distract from and undermine real action.

The American Chemistry Council is deathly afraid of effective policies that will actually reduce the production of plastics, because that means less chemicals to be sold to make plastics, Enck said. Theyre showing up, talking to legislators and saying dont reduce plastic packaging, we can just send it all to chemical recycling facilities, which is a lie. Thankfully they have not succeeded so far.

New Yorks bill is widely supported by activists, a majority of members of both the state Senate and Assembly, and even the mayor of New York City. Its fate, up against the full force of industry lobbying and disinformation, could signal whether these companies can still control the response to the crises theyve caused or whether theyre in for a reckoning.

In recent years, the ACC hasramped up its advertisingof chemical recycling technology as a solution to plastic waste as its member companies promise to construct new facilities alongside expanding petrochemical operations across the country.

But an Octoberreportby the International Pollutants Elimination Network (IPEN) and Beyond Plastics found that only 4 out of the 11 chemical recycling facilities that have been built in the U.S. are fully operational and even if all of them were fully operating, their combined capacity would represent just 1.3 percent of the plastic waste produced in the country per year.

Chemical recycling is more of a marketing and lobbying technique than an actual solution to the plastics problem, Enck said.

Plastic production is expected to double in the next20 years, and theclimateandpublic healthcrisesit creates are growing exponentially, too. Microplastics have been discovered in human blood, lungs, and breastmilk and most recentlyin human placentas. As oil and gas majors grow their plastics and petrochemical businesses as aPlan Bfor expanding fossil fuel operations, putting companies in the drivers seat does not bode well for actually reducing plastic waste, advocates say.

Still, the ACC will only back a producer responsibility system that would count chemical recycling facilities as recycling and be directed by the private sector. New Yorks bill, in contrast, would establish a new Office of Inspector General to ensure compliance and an advisory council that would include representatives from environmental justice communities.

The American Chemistry Council wants industry to run the program, said Dawn Henry, a former commissioner for the U.S. Virgin Islands Department of Planning and Natural Resources and senior adviser for Beyond Plastics. We cant allow that environmental justice demands that we leverage our political power to stop the plastic industry from polluting, exploiting, and expanding in vulnerable communities.

Those harms would only be further entrenched by chemical recycling, which iscarbon intensiveand involves emitting a mess of toxic chemicals and burning hazardous waste, according to Beyond Plasticsreport. Chemical recycling facilities and the materials they produce are often sited and sent to the same communities already most burdened by plastics production, said Henry, because companies are counting on their low political influence. Even if New York doesnt have its own chemical recycling facilities, the ACCs vision would mean New Yorkers would continue to exacerbate pollution in lower-income communities and communities of color like Louisianas Cancer Alley,a 170-mile stretch along the Gulf Coast littered with petrochemical and oil refining facilities sited primarily in Black communities.

We are in the belly of the beast, and our health is suffering from it, said Jo Banner, a lifelong resident of St. John the Baptist Parish and co-founder of Louisiana advocacy groupThe Descendants Project. Im not interested in their greenwashing campaigns, she said of the plastic industry. At the end of the day, they will only find a new way to poison us.

While campaigning for chemical recycling, the industry is working to kill policies that would actually curb its pollution. The Plastics Industry Association and 53 other companies and trade groupsfiled an opposition statementagainst the bill for its bans on toxic substances which they claim is without sound-scientific basis. The ACC paid lobbying firms in New York Statenearly $250,000during the 2023 legislative session increasing its spending by more than half fromtwo years prior. According to Beyond Plastics, the ACC has lobbied to water down producer responsibility bills in at least 10 other states, and has successfully lobbied 24 states to pass laws that weaken environmental protections against chemical recycling processes like pyrolysis and gasification (turning plastics into chemicals or more oil and gas).

As documented in anew reportby the Center for Climate Integrity (of which ExxonKnews is a project), oil and chemical companies and their trade associations have known for decades that plastic recycling was not an effective solution to plastic waste but colluded to deceive consumers into thinking it was. While telling lawmakers and the public they could just recycle plastic, they flooded the market with it, knowing most would end up in landfills and the ocean. As one Exxon employee told staffers at the American Plastics Council (APC) in 1994 about plastic recycling, We are com
mitted to the activities, but not committed to the results.

That remains true today. As was the case with conventional recycling, the companies promoting pyrolysis know its a fundamentally uneconomical process, as Exxon Chemical Vice President Irwin Levowitz told APC staffers in 1994. The same year, SPI, a plastic industry trade association of which Exxon was a member, tried and failed to get the Oregon Attorney General to count it as real recycling so it could meet its targets in the state.

Yet since that evidence of the industrys deception was released, the ACC has doubled down. In astatementresponding to the CCI report, Ross Eisenberg, president of Americas Plastic Makers (a brand of the ACC), called plastics necessary to meet our renewable energy, clean water, connectivity, and global health and nutrition goals and claimed that investments in advanced recycling can be a game changer to better manage our vital plastic resources.

We are advocating for smart public policies that will unleash more investments and create an environment that will help modernize the way plastics are made and remade today and in the future, Eisenberg said.

Enck says the industry is just continuing to do what it has done for decades promote false solutions to prevent real ones. Just like the fossil fuel industry has lied about the impacts of climate change, the American Chemistry Council has lied about the role of conventional recycling for plastics and now theyre lying about chemical recycling, she said. They know that lawmakers want to do something to solve the problem, so they keep pushing the narrative that a breakthrough is right around the corner.

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Why the Oil and Chemical Lobby Is Taking Aim at New York's Plastic Waste Bill - DeSmog

What’s the most expensive piece of glassware you ever broke? Chemists share their stories – Chemistry World

Everyone whos ever worked in a lab knows the pain of when something goes horribly wrong. Used the wrong solvent? Check. Accidentally poured your product painstakingly isolated over several weeks down the sink? Check. Tipped acid in the organic waste bin? Whoops.Inadvertently made an explosive? Yikes.

This week Keith Hornberger, executive director, chemistry at clinical-stage biotechnology company Arvinas in the US, related on X, formerly Twitter, that his son was left feeling a bit unhappy after he broke a beaker in a school chemistry lab. In an effort to cheer his son up and make him feel a bit better about his lab disaster he asked for scientists best stories of the biggest or most expensive piece of glassware theyd ever broken.

The science community did not disappoint. There were over 100 different stories of scientists having a smashing time with particularly expensive equipment, hazardous substances and precious metals. Weve picked out some of our highlights.

The biggest piece of glassware to go tinkle?

And the most expensive mishap? Oof!

After all these tales of glassware woes there is a happy ending though. At least one person felt better as a result!

If you have your own story of a glassware disaster you can add it to the thread or share it with us below the line in the comments.

Correction: Keith Hornbergers affiliation should be Arvinas not Columbia University.

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What's the most expensive piece of glassware you ever broke? Chemists share their stories - Chemistry World

Hydrogen veterans have lithium-ion in crosshairs with ‘physics-meets-chemistry’ battery alternative – Recharge

A UK start-up led by veterans of the hydrogen sector has launched what it claims is a breakthrough energy storage technology that it hopes can take on industry-leading lithium-ion batteries.

Superdielectrics this week launched its hybrid energy storage technology, which it calls Faraday 1.

The Cambridge-based start-up said it has combined electric fields (physics) and conventional chemical storage (chemistry) to create a new aqueous polymer-based supercapacitor.

The start-up developed the tech with researchers at the University of Bristol, who identified and validated the key mechanisms involved.

Superdielectrics is commercialising technology arising from fundamental scientific research carried out at Bristol and the University of Surrey into aqueous polymers with what are described as exceptional electrochemical properties.

According to the start-up, this allows its technology to overcome the disadvantages that have hampered supercapacitors which store energy in magnetic fields in comparison to conventional batteries, while also offering positive advantages.

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Energy storage is crucial to helping bring more intermittent renewable energy sources such as wind and solar onto grids, helping to smooth out their natural fluctuations in output.

Pumped hydro storage and lithium-ion batteries dominate the energy storage sector currently but both have issues. Hydropower is limited to very specific mountainous geographies, while lithium-ion batteries rely on expensive critical minerals and have a habit of occasionally bursting into flames.

The technology behind the Faraday 1 has completed over 1 million hours of testing, said Superdielectrics.

This has created a system that it claims can already significantly outperform lead-acid batteries a commonly used type of battery that has relatively low power density.

Superdielectrics claimed its technology also has the potential, with further development, to match or exceed existing lithium-ion batteries.

The technology charges over ten times faster than lead-acid batteries and has a high cycle life, said Superdielectrics. It also has a negligible fire risk.

The new technology is also low cost as it uses readily available abundant raw materials, said Superdielectrics.

Jim Heathcote, CEO of Superdielectrics, claimed: The properties that our technology possess enables it to compete with and exceed current solutions in the energy storage arena across a number of key metrics whilst leading the way in sustainability, recyclability and affordability.

Heathcote and Superdielectrics finance chief Marcus Scott in its early years led ITM Power, the hydrogen fuel cell and electrolyser specialist that was one of the first movers in the H2 sector.

Professor David Fermin, head of the University of Bristol Electrochemistry and Solar Team, said that these state-of-the-art supercapacitors have the potential to become a game-changer in energy storage.

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Hydrogen veterans have lithium-ion in crosshairs with 'physics-meets-chemistry' battery alternative - Recharge

From one sinking ship to another? | Opinion – Chemistry World

Its not very often that you see a pharmaceutical company completely giving up on a drug thats already won regulatory approval and has reached the market at least not without uncovering some serious side effect that didnt show up in the clinical trials. With many of the difficult, risky parts of the process already traversed, it should be time to sell some product and recoup some investments. And you wouldnt have put all that effort into a product that you didnt believe was going to be able to do that, naturally.

But it does happen. A famous example was Exubera, an inhaled insulin product. The idea was that this route would be so much easier and faster than self-injection that it would capture a good share of a very large market. Pfizer had convinced itself of this, and had convinced a number of financial analysts as well. So, it came as a rude surprise when the product absolutely flopped. Physicians werent particularly interested in prescribing it, and patients werent particularly interested in trying it. The company withdrew it from the market the very next year. In another example, some of the early drugs approved against Hepatitis C were also abandoned quickly due to overwhelming competition and vanishing revenues.

The newest example is Aduhelm (aducanumab), the anti-amyloid antibody developed by Eisai and Biogen, which was (in)famously approved by the US Food and Drug Administration (FDA) despite the objections of its own advisory panel and its own statisticians. The controversy was so great that Medicare (the state-backed medical programme for over-65s, and a huge customer for any Alzheimers drug) refused to pay for it unless patients were involved in another clinical trial to determine if the drug actually had any real benefit. Youd think that would be the sort of question youd have cleared up before a drug hit the market, but for some reason the FDA decided that Everything Was Different Now.

Biogen announced recently that it is discontinuing Aduhelm, and this definitely wasnt due to overwhelming competition. There was nothing else like it on the market, but very, very few physicians were prescribing it after Medicare and other large insurers balked. The drug was also never approved in Europe or elsewhere. Unlike Pfizer with Exubera, though, Biogen had another reason to give up on Aduhelm: it has, along with Eisai, another anti-amyloid antibody approved Leqembi (lecanemab) and they want to concentrate their resources on that one. Truth be told, the clinical data for it are not (in my opinion) much more compelling than Aduhelms, and there are safety concerns as well. Standard opinion in the drug business has been that the first effective drug against Alzheimers would surely be a record-setting success, but that word effective is causing difficulties. Its possible that the word safe will also become troublesome; that will bear watching, too. The same concerns hold for donanemab another antibody from Eli Lilly that is expected to be approved soon.

You can draw different lessons from Aduhelms failure depending on your prior views. Libertarian types have long championed the idea of approving drugs based mostly on safety, and letting the independent judgments of physicians and patients sort things out afterwards. Aduhelm certainly wasnt approved on efficacy, so perhaps its failure at the hands of insurance (both public and private) is what the libertarians had in mind? But the heavy hand of the US government (in the form of Medicares rejection) surely spoils that story. You could also see the Medicare decision as the last line of defense holding against the effects of an unusually bad regulatory decision. From one perspective thats heartening, but it really shouldnt have to come to that. Medicare is not really designed as a drug approval mechanism. You can stop a car by overheating the emergency brake and steering into a wall of tyres, but thats not a sustainable way to drive to work.

So the progress of the next two antibodies will be of great interest. My opinion is that if the amyloid hypothesis for Alzheimers were as strong as we used to think it was, then these drugs should have led to greater things. If youd told everyone back in 1990 about their undeniable amyloid-clearing effects, the last clinical outcome youd have expected would be everyone having to squint their eyes and turn up the room lights to see any sort of real-world effect. The world is still waiting for a good Alzheimers drug. I cannot begin to guess when it might arrive.

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From one sinking ship to another? | Opinion - Chemistry World

US science funding hangs in the balance with continuing resolutions – Chemistry World

US president Joe Biden has signed another continuing resolution (CR) to maintain funding for government agencies and avoid a government shutdown for the time being, nearly half a year into the fiscal year, but many science advocates are not celebrating even though this keeps research funders afloat.

Funding the government with short-term continuing resolutions over five months into the fiscal year is dysfunctional, stated Sudip Parikh, the chief executive of the American Association for the Advancement of Science, in a 4 March statement. With the passage of this CR, Congress yet again takes only one step back from the brink of effectively surrendering our global leadership in science and technology to other nations that have chosen to prioritise investments in biomedical research, artificial intelligence, quantum computing, fusion, [science, technology, engineering, maths and medicine] education, and more, he continued.

If Congress fails to fund the federal government by 30 April, large automatic cuts to research and development will be triggered, Parikh warned. These cuts would have real and lasting consequences for the science and technology foundations of our future health, economy, and national security. He urged Congress to pass full-year appropriations bills before the end of April to ensure that US science and technology leadership is maintained.

With the latest CRs passage, the new funding deadline for several federal agencies and programmes is 8 March and for the remainder it is 22 March.

Meanwhile, just days after the CR was signed, congressional appropriators unveiled a six-bill funding package, dubbed a minibus, as a step to moving some agencies off a CR. But the research community had some concerns about that measure, which was released on 3 March.

For example, The Science Coalition representing more than 50 of Americas top public and private research universities cautioned that cuts to certain federal science agencies in the minibus, including the National Science Foundation (NSF), will restrict US research and innovation, impede progress on critical societal challenges, and jeopardise the USs scientific leadership.

While trends vary by agency, proposed cuts to vital federal science agencies like NSF are troubling, stated Science Coalition president Jill Pentimonti. She noted that the minibus would reduce the NSFs budget below the enacted level in its baseline funding.

The Association of American Universities president, Barbara Snyder, is pleased that Congress has reached agreement on a package of bills to fund a portion of the government through the end of fiscal year 2024. Nevertheless, she said she is deeply concerned about the budget proposed for the NSF in particular.

The funding proposed in the package would reduce NSFs capacity by almost $500 million or more than 5% below current levels, Snyder stated. By undercutting the NSFs work, we are gambling our nations future as a global leader in science and innovation.

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US science funding hangs in the balance with continuing resolutions - Chemistry World

Researchers provide unprecedented view into aerosol formation in Earths lower atmosphere – Argonne National Laboratory

Eighty-five percent of the Earths air resides in the lowest layer of its atmosphere, or troposphere. Yet, major gaps remain in our understanding of the atmospheric chemistry that drives changes in the tropospheres composition.

One especially important gap in knowledge is the formation and prevalence of secondary organic aerosols (SOAs), which impact the planets radiation balance, air quality and human health. But that gap is closing due to the groundbreaking discoveries of an international team of researchers led by the U.S. Department of Energys (DOE) Argonne National Laboratory, Sandia National Laboratories and NASAs Jet Propulsion Laboratory (JPL).

The scientists detail their findings in a new paper published this month in Nature Geosciences.

The team focused on a class of compounds known as Criegee intermediates (CIs). Researchers suspect that CIs play a critical role in the formation of SOAs when they combine via a process called oligomerization. But no one had ever directly identified the chemical signatures of this process in the field until now.

First, we discovered that CI chemistry may play a bigger role in altering the composition of the troposphere than current atmospheric models account for probably by an order of magnitude. Carl Percival, researcher at NASAs JPL

Using the most advanced methods available for detecting gas-phase molecules and aerosols in the atmosphere, the team took field measurements in the Amazon rainforest, one of the most crucial SOA areas on Earth. There, they found clear evidence consistent with reactions of a Criegee intermediate compound containing carbon, hydrogen and oxygen (CH2OO).

This discovery is extremely significant because we were able to make direct connections between what we actually saw in the field, what we anticipated was happening with oligomerization of CIs and what we were able to characterize in the lab and determine theoretically, explained Rebecca L. Caravan, an assistant chemist at Argonne and first author on the paper.

These field observations constitute just one component of the innovative science enabled by the collaboration across the laboratories.

In addition to the field measurements, we were able to employ the worlds most advanced experimental methods for directly characterizing the Criegee intermediate reactions. We used the most advanced theoretical kinetics to predict reactions we cant measure directly. And we took advantage of the most advanced global chemistry modeling to assess the effects we would expect oligomerization to have in the troposphere based on those kinetics, said Craig A. Taatjes, a combustion chemist at Sandia.

This combination of components produced some critically important findings.

First, we discovered that CI chemistry may play a bigger role in altering the composition of the troposphere than current atmospheric models account for probably by an order of magnitude, said Carl Percival, a researcher at NASAs Jet Propulsion Laboratory. Second, the updated modeling that we performed based on our work produced only a fraction of the oligomerization signatures we observed in the field.

This could mean that CI chemistry could be driving even more transformation within the troposphere, or that other, yet unidentified chemical mechanisms are at work.

We still have a lot of work to do to fully define the role of CI reactions in the troposphere, concluded Caravan. But these findings significantly expand our understanding of one potentially significant pathway for SOA formation in the most important layer of the earths atmosphere.

Besides Caravan, Argonne authors include Ahren Jasper and Stephen Klippenstein.

Funding for the work carried out at Argonne and Sandia was provided by DOEs Office of Science Basic Energy Sciences program and the National Nuclear Security Administration. NASA funded the research done at the Jet Propulsion Laboratory.

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Researchers provide unprecedented view into aerosol formation in Earths lower atmosphere - Argonne National Laboratory

Greg Voth delivers Borden Endowed Lecture in theoretical chemistry – Dailyuw

Greg Voth, a professor at the University of Chicagos department of chemistry, presented Overcoming the Multiscale Challenge for Biomolecular Systems on his findings in protein modeling during the UW department of chemistrys Borden Endowed Lecture on Feb. 28.

The Weston and Sheila Borden Endowed Lecture, which sponsors annual presentations by theoretical chemistry researchers, is one of five lectures supported by the departments endowed funds.

Voth, whose work focuses on computer simulations of biomolecules, has an extensive history with the biological applications of computation.

I started years ago, in college, and was fascinated by science, and especially theoretical science, Voth said. Somewhere, as I went through graduate school, computers became more and more powerful and available. And so you could kind of see the blending of scientific concepts with computation I realized these biological questions are really fascinating, and very challenging.

Voths lecture focused specifically on multiscale theory: the challenge of modeling intricate systems efficiently and accurately. His lab has completed this through ultra-coarse-grained (UCG) modeling systems that can interpret complicated biomolecular interactions while maintaining low resolution.

I do computer simulations, and we're very interested in dealing with very complex systems, usually ones involving biology, Voth said. The difficulty of using straightforward computer simulations to get at that [is that] they're very big; they take a long time to evolve These systems of interest [have] way too many atoms, so we have to develop special methods. And these are called multiscale methods theyre ways of dealing with this complexity.

Protein modeling innovations are especially important in understanding how biomolecules work. By modeling the human immunodeficiency virus (HIV) capsid, Voth hopes there will be advancements in understanding the virus.

In the specific case of HIV, we've discovered how a key part of the virus assembles, Voth said. [A virus] replicates in your infected cells and reassembles, and it goes and attacks another cell [If] we can understand key aspects of that, [we can] potentially find weaknesses that could be drug targets for therapeutics.

UCG modeling has also pushed the limitations of computational technology. Beth Fawcett, a masters student in chemistry at UW, remarked on the significance of the seminar.

I've worked in data science for five years, so it was really cool to see [this lecture], Fawcett said. After watching this talk, it seems like there's still going to be computational challenges, even though there's been a lot of advancements [in modeling proteins]. Theres been a wall for the number of computations you can do with traditional computing, so it was really cool to see that they were able to leverage what is currently available to get the HIV capsid model.

More information about the Voth groups research can be found here.

Reach contributing writer Amiya McLean at news@daily.com. X: @amiyamcllean

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Good Chemistry Bonds XPC Water with Orion Water Solutions – OILMAN Magazine

Multiple factors point to a successful 2024 for the oil and gas industry, with many betting on niche services. With the drive to enhance current services and increase efficiency, the service sector alone is well-positioned to prosper. Offering the best in service and beating the competition will secure business and establish relationships. Still, the critical component of the equation is finding that particular service or meeting that individual need that levies such a magnitude of success in driving up profits that the end user can only function with it.

Gary Griesenbeck, CEO of Orion Water Solutions, discovered the secret to success early when starting his company in 2016. Competing in the emerging market, Orion treats produced water generated through hydraulic fracturing, a staple to North American shales success. During the earlier years of operation, fracking, as hydraulic fracturing is commonly called, demanded massive quantities of fresh water to be used during operation. Due to the costs and demand for increasing amounts, science pointed to the potential in treating produced water that returns from the well during fracking.

It was a natural migration from using fresh water to produced water, says Griesenbeck.

No matter the water type used, according to Griesenbeck, it must be chemically treated to ensure safe use during fracking procedures. Bacteria and other components that contaminate frack water can damage the wellbore and cause such financial devastation that oil and gas companies would spend millions without seeing any positive return on the investment.

It is essential to keep naturally occurring bacteria and other contaminants out of the well, says Griesenbeck. We treat 500,000 to 600,000 barrels of water per day.

When considering Orions contribution of treated water per day and pairing that with estimations from other companies and competitors that conduct the same operation, the need to enhance that ability suddenly surfaces as a niche service that ensures increased profits.

Ivan Sager identified the available opportunity and utilized his technical background to establish XPC Water, a company focusing on water chemistry analytics and real-time data alerting. While companies like Orion own their data, the XPC platform acquires, normalizes, assesses and cultivates data to provide valuable insights to the end user, enabling a streamlined approach to managing water treatment.

According to Sager, the XPC platform is a multi-tenant application that uses advanced pattern recognition to categorize water quality and alert the user of critical spikes. Orion refers to its configuration on the platform as remote data visualization (RDV) that provides operators and managers the analytics needed to manage and monitor the injected chemicals before the water is sent downhole and then treat the water as it exits the wellbore called produced water.

Pennies spent on chemicals count when processing massive volumes of water and identifying overdosage or anomalies in the process is critical, says Sager.

Griesenbeck breaks his company service down into two equally essential services. Orion disinfects water going down the wellbore using chlorine dioxide (CLO2) and then treats the produced water through a Dissolvable Air Flotation (DAF) Process. These require a disciplined and focused approach to chemical management. Orion sets up remote processing sites at each fracking location to provide these services. As a result, managing the water chemistry of each specific site proves difficult, and errors can lead to loss of revenue.

XPC Water provides the solution by capturing and monitoring data centrally. The XPC platform records and reports all essential cost and performance data for each job site. This includes downtime, pump failure, and chemical use, which Griesenbeck estimates to be 20 to 30 percent of his sales. XPC provides reports, emails and text messaging that display chemistry data with a barrels per day trend and cost-to-treat data.

This information is essential, says Griesenbeck. A number diverging from the norm signals that something is wrong.

With XPCs ability to provide accurate data that can be managed in real-time, the operator can correctly add chemicals and treat water as needed. This influences chemical usage and provides the ability to refrain from wasting chemicals.

Staying on top of chemical usage greatly enhances efficiency and is often a make or break for operators, says Sager.

While oil and gas companies strive to streamline and refrain from enduring additional costs, when expenditures are made, they are typically costly. Software, automation and further areas of expense demand significant investment, but the XPC platform proves genius in its ability to be integrated with existing systems utilized by the end user.

How Orion generates data that is acquired by XPC has no relevance. Data cultivation is triggered on the XPC side of the equation. As a result, XPCs technology can be integrated with any data processing system.

Our goal is to remove friction and be the bridge to allow secure and rapid data collaboration and collaboration, says Sager. We simply integrate with other platforms. We format the data, and then the customer can import it, or we leverage our open standards Application Programming Interface (API).

Orion can retrieve the XPC data through its hardware compilation. While under habitat with XPC, the information resides in a secure cloud-based environment. Sager says by leveraging the end users existing investments, XPC ensures rapid implementation and profitability.

Technology knows few limitations, and when efficiency can be further improved, a place of necessity is established. Building upon the foundation of what XPC and Orion offer the industry, the company identified another outlet to enhance business needs. XPC is blazing the frontier of artificial intelligence with Chatxpc. This technology will optimize production operations by offering insights into the impact of multiple production parameters and suggesting the optimal production design. Additionally, it will play a role in real-time monitoring of production operations, identifying potential problems, and suggesting appropriate corrective actions.

AI is machine learning algorithms, and that data helps predict spikes and forecast chemical usage, says Sager. Generative AI will allow the operator to generate detailed content from the data that will be used in reports or management of the operations.

According to Sager, the primary advantage of Chatxpc lies in its ability to address technical issues quickly and accurately as they surface. Through its ability to recognize complex terms and concepts, Chatxpc will provide explanations and examples to assist the user in sending or accessing data more quickly.

The XPC technology depicts a robust picture of how it ensures efficiency and its positive fiscal impact can be forecasted in additional business areas. Griesenbeck sees a ne

ed for the XPC platform in multiple areas of the oil and gas industry alone.

The push for remote operations will require technology to support rapid data acquisition and analysis. The XPCs platform enables such a process. Additionally, as oil and gas companies attempt to manage aging infrastructure while constructing new, spill prevention becomes paramount. XPC would offer an invaluable service by providing the means to monitor pipeline levels and a medium for calculating the decrease in pipeline capacity after a spill. Accurate accounting of content
s that contact the earth is critical in managing environmental disasters.

With over 218 million barrels of water, XPC has perfected the niche in enabling efficiency and profitability in water treatment capabilities. With the abundance of possibilities, XPC can impact oil and gas for the greater good of the environment and its users.

Anyone using chemistry can benefit from the XPC platform, says Griesenbeck. Storage facilities, retailers and collection batteries for saltwater could all see ideal results. RDV has improved my profit margin easily by two to three percent.

Headline photo: From left to right: Tee Jay Hayes, Operator, and Anthony Yanez, Field Supervisor, verifying data at a produced water recycling location. Photos courtesy of XPC Water Solutions.

Freelance Writer and Photographer

Nick Vaccaro is a freelance writer and photographer. In addition to providing technical writing services, he is an HSE consultant in the oil and gas industry with twelve years of experience. Vaccaro also contributes to SHALE Oil and Gas Business Magazine, American Oil and Gas Investor, Oil and Gas Investor, Energies Magazine and Louisiana Sportsman Magazine. He has a BA in photojournalism from Loyola University and resides in the New Orleans area. Vaccaro can be reached at 985-966-0957 ornav@vaccarogroupllc.com.

3 Ways Technology is Going to Shape the Oil and Gas Industry Free to Download Today

Oil and gas operations are commonly found in remote locations far from company headquarters. Now, it's possible to monitor pump operations, collate and analyze seismic data, and track employees around the world from almost anywhere. Whether employees are in the office or in the field, the internet and related applications enable agreater multidirectional flow of information and control than ever before.

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Good Chemistry Bonds XPC Water with Orion Water Solutions - OILMAN Magazine

Frank Popoff, Who Sought to Lead a Friendlier Dow Chemical, Dies at 88 – The New York Times

Frank Popoff, who as chief executive and chairman tried to make Dow Chemical more conciliatory toward regulators and environmentalists in the late 1980s and 90s, and who prodded the chemical industry to adopt safer practices, died on Feb. 25 at his home in Midland, Mich., where Dow is based. He was 88.

A spokesman for the company said the cause was cancer.

When the Bulgarian-born Mr. Popoff was named Dows president and chief executive in 1987, the company had begun trying to shed its image as a pugnacious chemical giant that had manufactured napalm and the defoliant Agent Orange for the U.S. military during the Vietnam War; released toxic waste, like dioxins, into the Tittabawassee River from its plant in Midland; and fought the Environmental Protection Agency to prevent flyover inspections of its emissions.

An estimated $50 million advertising campaign, begun two years before Mr. Popoff rose to the top, used the slogan Dow lets you do great things. It was intended to change public perceptions of Dow, promoting an image of it as a nicer corporation, underlining its charitable giving and humanitarian uses of its products.

I think we have a fair amount of work to do in terms of the way we are viewed, Mr. Popoff told The New York Times in 1987, shortly before succeeding Paul F. Oreffice as chief executive. We know well never change Ralph Naders mind. But Dow is at peace with itself, and we want our people to feel good about the company, too.

The company was best known then for manufacturing chemicals, including chlorine, as well as for using chemicals in making plastics, pharmaceuticals and supermarket goods like Saran Wrap, Fantastik cleaning liquid and Ziploc bags.

Regulators and environmentalists were heavily focused on chemicals at the time. In 1991, Mr. Popoff and another Dow executive, David Buzzelli, set up a panel of outside environmental policy advisers among them Lee Thomas, a former E.P.A. administrator who scrutinized Dows operations and were able to obtain confidential information. A current version of that panel remains in place at Dow.

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Frank Popoff, Who Sought to Lead a Friendlier Dow Chemical, Dies at 88 - The New York Times

Chemistry taking Mount Zion boys basketball to doorstep of state title – Herald & Review

MOUNT ZION Every day in the summer since he was a little kid, JC Anderson would be in the driveway with friends playing pickup basketball.

That group included Lyncoln Koester, Sam Driscoll, Brayden Trimble and Anderson, with Koester winning the games to 21 most often between the four.

Mount Zion celebrates its 47-46 win of the 3A Springfield Super-sectional boys basketball game against Centralia at the BOS Center. The Braves' players have a bond that started as kids.

Now, Koester is the Braves' leading scorer and Anderson is a dominant post presence while Trimble and Driscoll are playing key roles as starters on a 35-1 team that will play in its first-ever state tournament this weekend with a 9:30 a.m. tip on Friday against Chicago Mount Carmel in the IHSA Class 3A State Tournament semifinals in Champaign.

"I remember it like it was yesterday, man," Anderson said. "Off each other, we just thrived."

Mount Zion's Grant McAtee takes the ball to the basket earlier this season.

Andersons mother, Becky Clayton-Anderson, would, from in the house, hear them mixing it up as little kids years before theyd grow up and become one of the most dominant basketball teams in the state, and the best team in Mount Zion history.

"It was just the best thing as a basketball player watching them all out there just playing, and they would fight and hit and punch and cuss at each other, and then they'd get done playing and they're just best friends," Clayton-Anderson said. "I just smile ear to ear every time they're out there playing because that's what it's all about growing up together and playing together. They just always have each other's backs; they always have."

The Braves beat Centralia 47-46 on Monday at the Class 3A Springfield Super-sectionals, overcoming a seven-point fourth-quarter deficit after a season where their offense has helped them mow through most of the teams in their path. Mount Zion averages 64.3 points per game, but its grit helped it overcome an early deficit against local rival MacArthur in the sectional finals as well.

Mount Zion players celebrate their 47-46 super-sectional win.

"They just don't give up," Braves coach Dale Schuring said. "They've got a determination and grit and a toughness to them that you've got to have in these types of situations. They've shown it every time we've needed it and they came through again."

That winning edge has been slowly building with the Braves as their roster got older. With juniors like Koester, Driscoll and Trimble, along with senior starter Grant McAtee, theres years of experience throughout the teams lineup. Thats a big reason why the team has put together a record-breaking run after a 1-14 record in 2020-21.

"It takes time," Schuring said. "The juniors ... they've been playing since they were freshmen, but 14-year-olds against 17- and 18-year olds, it's not as fair as you would think no matter how talented you are. It's a progression. They've gotten stronger; they've gotten better. It's so gratifying for them that they've shown that and they get the opportunity to go to state."

As the players grew physically and mentally over the past few seasons theyve become a local juggernaut. They feature high-level athletes, but its the understanding and speed they can play with together that has allowed the Braves to go on a special postseason run.

Mount Zion's JC Anderson celebrates during the Braves' win against Centralia in the super-sectionals.

"We knew we always had the potential to be big, but I think it's just Coach Schuring helped us a lot," Anderson said. "He disciplined us and he helped our heads not get too big. So it's just been being patient and waiting for our turn."

The Braves are ready to take the intensity they built in their games in the Anderson driveway to the floor at the State Farm Center.

"It's a special group," Anderson said. "Words can't explain it. No one believed we'd be here. We don't have five-star players. We don't have (Division I) basketball recruits, but we have chemistry like no other."

Signs cheer on the Mt. Zion boys basketball team, who are heading to the state final for the first time, outside McGaughey Elementary School on Thursday.

Jill Sams puts up signs in town for the Mt. Zion boys basketball team, who are heading to the state final for the first time, on Thursday.

Whitney Getz, Kamry Getz, 4, and Macklin Sams, 3, put up signs in town for the Mt. Zion boys basketball team, who are heading to the state final for the first time, on Thursday.

Signs cheer on the boys basketball team, who are heading to the state final for the first time, in Mt. Zion on Thursday.

Mount Zion senior Tyson Evans high-fives basketball team members Thursday as the Braves head to the State Farm Center in Champaign for the state final tournament.

Mount Zion students cheer as the boys basketball team heads to the State Farm Center in Champaign for the state final tournament on Thursday.

The Mount Zion boys basketball team proceeds past students on the way to the bus on Thursday to head to the State Farm Center in Champaign and prepare for the state final tournament.

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Chemours suspends chief and senior executives over accounting issues – Chemistry World

Chemical giant Chemours has suspended three senior executives, including its chief executive and chief financial officer, pending an internal review over suspicious accounting and compensation practices.

The DuPont spin-off postponed reporting its 2023 financial results in mid-February, saying it needed extra time to complete the reporting process. But on 29 February there were further revelations, with chief executive Mark Newman, chief financial officer Jonathan Lock, and principal accounting officer Camela Wisel placed on administrative leave for the duration of the review.

The review will be overseen by auditors and independent lawyers. It will focus on processes for reviewing reports made to the Chemours ethics hotline, and practices for managing working capital, including company metrics that impact financial incentives for senior managers. In submissions to the US Securities and Exchange Commission, Chemours provided estimates of its top line financials for 2023, and promised to file official, audited figures as soon as practicable.

This is about as serious as you could get. The suggestion is that the financials were off, and they were allegedly done in an improper way, says Charles Elson, founding director of the Weinberg Center for Corporate Governance at the University of Delaware, US. Theyre saying that the numbers on which the incentives plans were based many be inaccurate and people may have been overpaid based on the metrics that were reported.

Theyre going to have to go back and reconstruct the actual financial performance of the company for the period involved, says Elson. The audit committee [likely] had a whistleblower; they investigated and found that there was substance to the accusations.

This is a shock. DuPont was a staid, conservative, blue-blood company and it was assumed that Chemours was similar, but these are serious allegations, says Elson. To remove both a [chief executive] and the [chief financial officer] is very rare.

Chemours share price dropped by around half following the announcement. Several days later, it remains down almost a third. Market analyst Michael Leithead at Barclays said in a note to investors: What we think many perceived as a relatively minor accounting hang-up two weeks ago now appears wider, longer, and with more ramifications than the market initially believed.

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Chemours suspends chief and senior executives over accounting issues - Chemistry World

Harmful ‘forever chemicals’ removed from water with new electrocatalysis method – University of Rochester

Scientists from the University of Rochesterhave developed new electrochemical approaches to clean up pollution from forever chemicals found in clothing, food packaging, firefighting foams, and a wide array of other products. A new Journal of Catalysis study describes nanocatalysts developed to remediate per- and polyfluoroalkyl substances, known as PFAS.

The researchers, led by assistant professor of chemical engineering Astrid Muller, focused on a specific type of PFAS called Perfluorooctane sulfonate (PFOS), which was once widely used for stain-resistant products but is now banned in much of the world for its harm to human and animal health. PFOS is still widespread and persistent in the environment despite being phased out by US manufacturers in the early 2000s, continuing to show up in water supplies.

Muller and her team of materials science PhD students created the nanocatalysts using her unique combination of expertise in ultrafast lasers, materials science, chemistry, and chemical engineering.

Using pulsed laser in liquid synthesis, we can control the surface chemistry of these catalysts in ways you cannot do in traditional wet chemistry methods, says Muller. You can control the size of the resulting nanoparticles through the light-matter interaction, basically blasting them apart.

The scientists then adhere the nanoparticles to carbon paper that is hydrophilic, or attracted to water molecules. That provides a cheap substrate with a high surface area. Using lithium hydroxide at high concentrations, they completely defluorinated the PFOS chemicals.

Muller says that for the process to work at a large scale, they will need to treat at least a cubic meter at a time. Crucially, their novel approach uses all nonprecious metals, unlike existing methods that require boron-doped diamond. By their calculations, treating a cubic meter of polluted water using boron-doped diamond would cost $8.5 million; the new method is nearly 100 times cheaper.

In future studies, Muller hopes to understand why lithium hydroxide works so well and whether even less expensive, more abundant materials can be substituted to bring the cost down further. She also wants to apply the method to an array of PFAS chemicals that are still prevalently used but have been linked to health issues ranging from development in babies to kidney cancer.

Muller says that despite their issues, outright banning all PFAS chemicals and substances is not practical because of their usefulness in not only consumer products, but in green technologies as well.

I would argue that in the end, a lot of decarbonization effortsfrom geothermal heat pumps to efficient refrigeration to solar cellsdepend on the availability of PFAS, says Muller. I believe its possible to use PFAS in a circular, sustainable way if we can leverage electrocatalytic solutions to break fluorocarbon bonds and get the fluoride back out safely without putting it into the environment.

Although commercialization is a long way off, Muller filed a patent with support from URVentures, and foresees it being used at wastewater treatment facilities and by companies to clean up contaminated sites where they used to produce these PFAS chemicals. She also calls it a social justice issue.

Often in areas with lower income across the globe, theres more pollution, says Muller. An advantage of an electrocatalytic approach is that you can use it in a distributed fashion with a small footprint using electricity from solar panels.

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Harmful 'forever chemicals' removed from water with new electrocatalysis method - University of Rochester

Linnemann’s baskets and distillation in the early days of understanding equilibrium – Chemistry World

Much of chemistry is taught in metaphors: electron clouds, energy flows, close-packed spheres, reaction landscapes and flipping magnets. These pictures, while embedded into a deeper theoretical structure, provide mental shortcuts that help make predictions, formulate experiments and cement understanding. And yet, danger lurks in such ideas; they can also prevent us from seeing things that might otherwise be obvious. As the biologist and cybernetics guru Norbert Weiner wrote so pithily, The price of metaphor is eternal vigilance.

This phrase came to my mind when I was trying to make sense of the strange lineage of apparatus that I first saw in the stores of the Science Museum in London. Early in the 19th century, chemical distillation underwent a transition, driven by the need to separate members of the homologous series of organic compounds. Small differences in boiling temperature between, say, butyl and amyl alcohol meant that the use of a traditional retort (a bent, long-necked flask) required multiple distillations to obtain pure material. When Adolphe Wurtz introduced his tube bulles (bubble tube) one-shot distillations with good separation became standard.

But how did it work? There was little real understanding: key concepts like equilibrium, vapour pressure, temperature and energy were still, at best, in their infancy. Distillation theory was based around the rise of the lighter ethereal vapour and the descent of the wet phlegm. The spirits industry described the process as washing; what today we would call fractionation was called dephlegmation. In the 1820s the FrenchBelgian still designer Jean-Baptiste Cellier-Blumenthal mashed up several designs to create the first highly efficient continuous still with bubble trays, horizontal platforms arranged in stacks where the vapour bubbled its way through the descending wash.

The difference would be spotted by Eduard Linnemann. Born in Frankfurt am Main, he studied chemistry in Heidelberg, taught by Robert Bunsen and August Kekul. Linnemann followed Kekul to Ghent as his assistant before heading to Lemberg in Galicia (today Lviv, Ukraine) to become assistant to another ex-Heidelberg academic, Leopold von Pebal. He got lucky. Just as Linnemann secured his habilitation, von Pebal received the call from the University of Graz and decamped, leaving Linnemann to slide seamlessly into his place in 1865. He was soon full professor.

Throughout this time, Linnemann had been working on homologous series, publishing boiling temperatures and helping to reinforce the structural theory of chemistry. In 1871, he unveiled a new design of fractionator. His paper reveals a hint of insecurity, observing that laboratory distillation lagged far behind industry. In industrial installations a kind of washing takes place because the vapour is compressed and forced to bubble through the liquid. This washing is not possible in a simple or even Wurtz distillation. He therefore proposed a new fractionator that combined the two approaches: little baskets of platinum mesh inserted at intervals in the tube to collect the liquid, making washing possible.Furthermore, as flames were used for heating, superheated vapour never reached the thermometer, yielding more accurate boiling temperatures.

Linnemanns paper was widely read and his method was adopted in textbooks of organic chemistry, including Ludwig Gattermanns. Yet when our glassblower, John Cowley, built one for me a couple of years ago with little copper mesh baskets, the results were rather maddening the baskets filled with liquid and the fractionator tended to belch liquid upwards unless the flask was heated extremely slowly. This flooding issue was well known and spurred the development of several dozen designs over the next 40 years, sporting little funnels, glass loops and channels. All but one has disappeared: only the Snyder column survives, used with the Kuderna-Danish pesticide residue concentrator. Its glass beads serve to create pools of liquid that prevent the analyte escaping with solvent aerosol.

But for Linnemann there was also trauma: Galicia was granted increasing autonomy and the university was polonised. He lost his post, moving first to Brnn (today Brno in the Czech Republic) and then to Prague. His interests shifted to the search for new rare earth elements. Though increasingly ill he continued to work in the lab. While analysing the mineral orthite, a silicate with a peculiar composition, he observed new lines in the flame spectrum of an acid extract. Convinced that he had discovered a new element, he wrote a paper on his deathbed announcing the discovery of austrium. It was not to be. Months after his death, the Austrian chemist Richard Pribram and Paul-mile Lecoq de Boisbaudran, the French element hunter-extraordinaire, showed the spectral lines to correspond to those of one of Lecoqs own elements, gallium. Linnemanns name would fade into obscurity.

Was Linnemanns thinking trapped by the seductively simple idea of washing? That suspicion makes me very nervous. How many deeply embedded metaphors prevent us from seeing things that are deep and important?

I amgrateful to Talitha Humphrey who tested Linnemanns and other columns and began to exhume his story. Rupert Cole also invited me into the Science Museum stores and Philip Ball put Norbert Weiner on my map.

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Linnemann's baskets and distillation in the early days of understanding equilibrium - Chemistry World

The community of colleagues supporting each other through redundancy – Chemistry World

Last November, Pfizer announced plans to discontinue its Pharmaceutical Sciences Small Molecule capabilities at its Discovery Park location in Sandwich, UK, to consolidate the facilities at two primary sites, one in the US and one in India.

This decision impacted approximately 500 roles, more than half of the 940 people currently employed at the facility.

Research fellow Ivan Marziano was one of those to be made redundant, along with his entire team.

It was a set of very well interconnected teams that were affected, says Marziano, who marked his 25th anniversary at Pfizer on 1 January. Its always a very shocking thing to hear and it takes a lot of time to process, he adds. Im still on my first job I started working for Pfizer initially as a contractor a week before I had my PhD viva and Ive been here ever since.

The news was met with an immediate outpouring of support from the scientific community. At the time of the announcement, Marziano was in a large external meeting and describes the response as amazing.

The news hit the mainstream press straight away so people were aware of what was going on. There were a number of academic and industrial institutions at the meeting that we were in who wanted to help as much as possible.

Another colleague attending that same meeting was Rohan. Rohan, who was also informed that his job was at risk, had the spontaneous idea of setting up a hashtag and group #SandwichTogether on LinkedIn to enable the wider scientific community to support those affected.

Growing up in what he describes as a financially humble background in India, Rohan said that in his experience, people affected by adversity tend to help each other. Its a natural instinct, he explains. It became my coping mechanism.

I thought, I need to be with people to feel that Im not alone in this, so I created the hashtag and invited my friends, they invited their friends and now we have so many people in that group, he adds.

The group now has around 440 members and hundreds of posts highlighting vacancies and new opportunities have been shared using the hashtag, as have offers of support to help with skills such as CV writing, networking and interview preparation.

Its fantastic to get that this this level of support from the wider community, but also it sends a message of hope, says Marziano.

Rohan said he really started to see the advantages of the group when recruiters began to ask to join the group. One of these was Reiss McNally, co-founder of Molecular Search, which specialises in recruitment for contract development and manufacturing organisations. McNally says he felt a sense of responsibility to highlight the roles his organisation had available.

Although he had seen similar hashtags being used before, none had had the longevity of #SandwichTogether. I think because its on a larger scale, there is a lot more collaboration and people are asking how do we support the community? outside of just saying, good luck, hopefully you obtain a role.

McNally said that those working at Sandwich have a breadth of experience that a lot of companies would value. He recommends that those who have been made redundant try to ignore the negative connotations of being made redundant and focus on the unique skill set that you have because youre going to be an asset to another business straightaway.

I look at the colleagues around me and think organisation X will be very lucky to have you

Ivan Marziano

It is this kind of outlook that has been key to Marziano and his team when considering the future.

Without a clear sense of direction, or an understanding of what the opportunities are, it can be very easy to get yourself in a slump, he says.

I have 500 colleagues who are affected by this process and the first question that springs to mind is, where are the 500 of us going to end up? This helps colleagues to think about their next career steps and having that knowledge of whats out there can help catalyse some thoughts in that direction.

I look at the colleagues around me and think organisation X will be very lucky to have you, Marziano continues. We are ultimately looking for that win-win situation part of it is the support of the community [which], from a humane perspective, has been amazing, but lets not forget that there are also business advantages here, because you are dealing with incredibly competent and well-trained scientists.

Rohan says he is not surprised by the response to the hashtag because it reflects the positive attitude and culture already in existence at the Sandwich site. We help each other a lot, he says.

If I find a job that is suitable for me, as well as my colleagues, and if I share it with my colleagues, then I compete with them instead of competing with people who are unknown. And then if one of us gets it we can facilitate others getting suitable jobs in that organisation.

Marziano says the hashtag has helped to promote a sense of collective ownership.

The community was shaken up but since then, [#SandwichTogether has] just snowballed. Its a powerful mechanism to show how much impact social media can have in a constructive way.

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The community of colleagues supporting each other through redundancy - Chemistry World

This Could Be How the Earth’s First Cells Formed – Popular Mechanics

Everyone wants to know the answer to how

As a chemist at the California-based Scripps Research, Krishnamurthy has investigated the rise of RNA, the bridge between prebiotic chemistry to protobiology, and the complex emergence of protocellsa kind of ancestor of cells that make up all living things. Krishnamurthy even co-leads a NASA Astrobiology initiative investigating the origins of life on Earth.

Now, Krishnamurthy and his team have potentially uncovered another missing piece of Earths biological puzzle: the method behind the formation of the very first cells. In a new paper published in the journal Chem, scientists discovered that a process called phosphorylationwhen a phosphate group is attached to a moleculecould have occurred much early in Earths history, and created a pathway for the creation of protocells from fatty acids.

Weve now discovered a plausible way that phosphates could have been incorporated into cell-like structures earlier than previously thought, which lays the building blocks for life, Krishnamurthy said in a press statement. This finding helps us better understand the chemical environments of early Earth so we can uncover the origins of life and how life can evolve on early Earth.

The big question for Krishnamurthy and his team, according to the researchers, was trying to figure out how these protocells transitioned to a double chain of phosphatesa structure that is more stable and can create chemical reactions. To understand this, the team recreated the conditions of early Earth in the lab by using chemicals such as fatty acids and glycerol. These mixed solutions were cooled, heated, and shaken to stimulate chemical reactions. They were also tested with different ratios, temperatures, and pH levels to investigate how these structures form. By also including dyes, the researchers could witness the formation of vesicles, which are similar to protocells.

It turns out the fatty acids were able to transition to a phospholipid environment, suggesting that phosphorylation could have taken place much earlier than previously believed. The theory of this process occurring so early is backed up by the fact that phosphates are present in nearly every chemical reaction in the body, according to the press statement. Because of this, the likelihood of them playing a critical role in the development of life on Earth was pretty high.

Weve discovered one plausible pathway for how phospholipids could have emerged during this chemical evolutionary process, Scripps research biophysicist Ashok Deniz said in a press statement. Phospholipids are a further evolved vesicle membrane. Its exciting to uncover how early chemistries may have transitioned to allow for life on Earth. Our findings also hint at a wealth of intriguing physics that may have played key functional roles along the way to modern cells.

While this is an important step in understanding the complex chemistry that eventually gave rise to Earths stunning biodiversity, scientists still have a long way to go before confidently uncovering the whole story. For Krishnamurthy, and the rest of his team, the work continues.

Darren lives in Portland, has a cat, and writes/edits about sci-fi and how our world works. You can find his previous stuff at Gizmodo and Paste if you look hard enough.

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This Could Be How the Earth's First Cells Formed - Popular Mechanics

Lithium-ion batteries don’t work well in the cold a battery researcher explains the chemistry at low temperatures – The Conversation

Rechargeable batteries are great for storing energy and powering electronics from smartphones to electric vehicles. In cold environments, however, they can be more difficult to charge and may even catch on fire.

Im a mechanical engineering professor whos been interested in batteries since college. I now lead a battery research group at Drexel University.

In just this past decade, I have watched the price of lithium-ion batteries drop as the production market has grown much larger. Future projections predict the market could reach thousands of GWh per year by 2030, a significant increase.

But, lithium-ion batteries arent perfect this rise comes with risks, such as their tendency to slow down during cold weather and even catch on fire.

The electrochemical energy storage within batteries works by storing electricity in the form of ions. Ions are atoms that have a nonzero charge because they have either too many or not enough electrons.

When you plug in your electric car or phone, the electricity provided by the outlet drives these ions from the batterys positive electrode into its negative electrode. The electrodes are solid materials in a battery that can store ions, and all batteries have both a positive and a negative electrode.

Electrons pass through the battery as electricity. With each electron that passes to one electrode, a lithium ion also passes into the same electrode. This ensures the balance of charges in the battery. As you drive your car, the stored ions in the negative electrode move back to the positive electrode, and the resulting flow of electricity powers the motor.

While AA or AAA batteries can power small electronics, they can be used only once and cannot be charged. Rechargeable Li-ion batteries can operate for thousands of cycles of full charge and discharge. For each cycle, they can also store a much higher amount of charge than an AA or AAA battery.

Since lithium is the lightest metal, it has a high specific capacity, meaning it can store a huge amount of charge per weight. This is why lithium-ion batteries are useful not just for portable electronics but for powering modes of transportation with limited weight or volume, such as electric cars.

However, lithium-ion batteries have risks that AA or AAA batteries dont. For one, theyre more likely to catch on fire. For example, the number of electric bike battery fires reported in New York City has increased from 30 to nearly 300 in the past five years.

Lots of different issues can cause a battery fire. Poorly manufactured cells could contain defects, such as trace impurities or particles left behind from the manufacturing process, that increase the risk of an internal failure.

Climate can also affect battery operation. Electric vehicle sales have increased across the U.S., particularly in cold regions such as the Northeast and Midwest, where the frigid temperatures can hinder battery performance.

Batteries contain fluids called electrolytes, and cold temperatures cause fluids to flow more slowly. So, the electrolytes in batteries slow and thicken in the cold, causing the lithium ions inside to move slower. This slowdown can prevent the lithium ions from properly inserting into the electrodes. Instead, they may deposit on the electrode surface and form lithium metal.

If too much lithium deposits on the electrodes surface during charging, it may cause an internal short circuit. This process can start a battery fire.

My research group, along with many others, is studying how to make batteries that operate more efficiently in the cold.

For example, researchers are exploring swapping out the usual battery electrolyte and replacing it with an alternative electrolyte that doesnt thicken at cold temperatures. Another potential option is heating up the battery pack before charging so that the charging process occurs at a warmer temperature.

My group is also investigating new types of batteries beyond lithium ion. These could be battery types that are more stable at wider temperature ranges, types that dont even use liquid electrolytes at all, or batteries that use sodium instead of lithium. Sodium-ion batteries could work well and cost less, as sodium is a very abundant resource.

Solid-state batteries use solid electrolytes that arent flammable, which reduces the risk of fire. But these batteries dont work quite as well as Li-ion batteries, so itll take more research to tell whether these are a good option.

Lithium-ion batteries power technologies that people across the country use every day, and research in these areas aims to find solutions that will make this technology even safer for the consumer.

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Lithium-ion batteries don't work well in the cold a battery researcher explains the chemistry at low temperatures - The Conversation