University of Michigan police say safety will be top priority at psychedelic shroom festival – MLive.com

ANN ARBOR, MI University of Michigan police are planning to keep an eye on a psychedelic plant and mushroom festival planned for Sept. 19 on the UM Diag in Ann Arbor.

Our top priority is ensuring the safety of the community, said Melissa Overton, UMs deputy police chief. Any significant violation of state or federal law or any use of entheogenic plants that poses a threat to public health, safety and welfare still could result in law enforcement involvement.

A group called Decriminalize Nature Michigan is organizing the three-hour event known as EntheoFest to celebrate the one-year anniversary of Ann Arbors move to declare entheogenic plants and fungi the citys lowest law-enforcement priority, effectively decriminalizing them at the city level.

That includes ayahuasca, ibogaine, mescaline, peyote, psilocybin mushrooms and other natural compounds with hallucinogenic properties deemed illegal under state and federal law, though not synthetic compounds like LSD.

UM police enforce state laws and technically still can make arrests for such substances on campus.

Shroom festival planned in Ann Arbor to celebrate psychedelic awareness month

Next months festival on the Diag is expected to include speakers, musical entertainment and educational booths, followed by a walk to UMs Nichols Arboretum.

Decriminalize Nature Michigan is coordinating with a student group known as the Student Association for Psychedelic Studies, which has reserved the Diag, organizers said.

Moss Herberholz, the student groups president, described it as a sacred plant and mushroom festival with a focus on Mother Nature and the incredible plants and fungi that she provides.

UM spokesman Rick Fitzgerald said the student groups application for use of the Diag is still under review.

Local psychedelics activist Chuck Ream is secretary of Decriminalize Nature Michigan, which grew out of Decriminalize Nature Ann Arbor. Ream said he supports good policing and agrees with the UM police about focusing on public health, safety and welfare.

This is a free speech event, Ream said. This is not a chance to come in and get really high. You can do that at home and we would prefer that you did that at home.

The festival is for people to come together to share information and enthusiasm about psychedelic plants and fungi and how they can be used for therapeutic and spiritual purposes, in addition to enjoyment, Ream said.

He expects about 200 to 300 people will show up, though its hard to predict and there could be as many as 2,000 to 3,000, he said. He doesnt expect police to bother people who arent bothering anyone, he said, and as a former government official and kindergarten teacher, his advice to festival-goers is, Everybody better behave properly.

We dont see it as a place to get high, he said. If someone is high, theyll be smiling a lot and that wont bother anyone at all. I assume police wont bust people for smiling too much.

Ream said he once drank a magic mushroom-infused tea and the next day his face hurt from smiling so much. He has used psychedelics for spiritual exploration, seeking what Mother God wants him to do to help save the earth, he said.

Its going to be mainly a shroom fest, in terms of what people are involved in now, he said of EntheoFest, adding it also will focus on other entheogenic plants with which people could become more involved in the future.

Jim Salome, Decriminalize Nature Michigan deputy director, said EntheoFest is a celebration of sacred medicines.

The organizing group will be advising people not to take any psychedelics at the event, Salome said.

Its not a party necessarily, he said, adding its a way to build the movement and also motivate people to contact state lawmakers to get Michigan laws changed.

Washtenaw County Prosecutor Eli Savit, state Rep. Yousef Rabhi, D-Ann Arbor, and state Sen. Jeff Irwin, D-Ann Arbor, are on the list of speakers for EntheoFest.

Savit has taken a stance against criminally charging people for use, possession or small-scale distribution of entheogenic plants and fungi, and Irwin has said he plans to introduce legislation next month to try to decriminalize the natural substances across Michigan.

After success in Ann Arbor, Decriminalize Nature Michigan has been working to advance its cause in other cities, including Lansing, East Lansing and Hazel Park. The group anticipates Grand Rapids and Detroit will act on the issue in the coming months.

I think this is really historic and happening fast, Ream said.

Organizers said theres still a chance EntheoFest could be canceled due to COVID-19 concerns. Theyre watching infection rates and case counts and waiting to see what decisions UM makes about campus events in the next month.

Were watching the numbers every day, Ream said. This whole thing is about health and safety and wholesomeness and we cannot have it become a vector of disease.

City Council voted 10-0 this week to approve a resolution declaring September to be Entheogenic Plant and Fungi Awareness Month, in hopes of increasing understanding of the potential benefits of psilocybin mushrooms and other psychedelic plants and fungi for mental health, personal and spiritual growth, as well as honoring the longstanding ancestral practices and relationships with these entheogens.

EntheoFest, which is planned for the same venue as the long-running Hash Bash marijuana rally in Ann Arbor, will take place every September, the council resolution states.

Clinical studies and research in the U.S., Canada and Europe have shown the safety and efficacy of entheogenic plants/fungi for treating a variety of mental health illnesses going back to the 1960s, the resolution states.

Further, it adds: The FDA has granted breakthrough therapy designation to psilocybin for use in major depressive disorders; psilocybin has been shown to ease treatment-resistant depression, end-of-life anxiety and cluster headaches, ibogaine has been shown to be an effective treatment for opiate addiction, and ayahuasca studies are currently underway to better understand its ability to address depression and substance dependence.

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University of Michigan police say safety will be top priority at psychedelic shroom festival - MLive.com

Psychedelic Drug Therapy: Tips and Support for the Experience – Greatist

The fear began creeping in when I realized that I could no longer remember who I was.

I knew that I was on a beach beneath the starry sky, but concrete information like my name, past, where I was, or how Id gotten there were all frightfully elusive. I knew that I probably should recall my identity, but try as I might, I could not. As my mind spun and my heart galloped, the fear continued to bloom.

And then a thought arose: this feels familiar. There was a sensation coursing through me that I couldnt quite distinguish, but Id experienced it before. Wait I got it

I was bad tripping on LSD.

With this awareness came the understanding that, with time, my identity would ebb back in like the tide. No need to freak out. It was just a matter of time. At that moment I could be content to merely sit and consider the stars. The panic subsided. Bad trip averted, but only just.

Psychedelics arent new. In fact, thats an understatement, as psychedelics have been an integral aspect of human society for thousands of years. Come to think of it, what is rather new is their repression, which was virtually unheard of until LSD was banned in the United States back in 1967.

This prohibition put an effective end to mainstream research on substances like LSD, psilocybin (the delightful compound in so-called magic mushrooms), and mescaline for several decades, but the movement continued to bubble underground. Recently however, psychedelics also widely known as entheogens are enjoying a major comeback.

The FDA has declared that psilocybin and MDMA have the potential to be game-changing therapy tools. Cities and states have been decriminalizing the drugs left and right. Psychedelic therapy clinics are popping up across the country and around the globe, and there are even psychedelic stocks being traded on the market.

According to Dr. Julie Holland, a worldwide expert on street drugs and member of the Advisory Board at a psychedelic support organization called the Fireside Project, Clinical research is underway to see if psilocybin mushrooms may help to treat depression or the existential anxiety that often accompanies a terminal illness (at Johns Hopkins), or to treat addiction to alcohol (at NYU), cigarettes (Hopkins), or cocaine (in Alabama).

MDMA-assisted psychotherapy is being studied for the treatment of post-traumatic stress disorder (multi-center Phase IIII trials), and psilocybin is being studied in the treatment of obsessive-compulsive disorder (OCD) at Yale.

Suffice to say that with their potentially wide-ranging benefits, psychedelics might be one of the cures to what ails you.

That being said, its possible for the darkness to eclipse your trip regardless of your intentions. Theres only so much you can do to tame a tiger, and these substances have vivid stripes.

With this in mind, the Fireside Project has launched a new app to provide peer-to-peer support for psychonauts undergoing the rigors of a rough trip.

At the press of a button, the app connects you with an ambassador to walk you through the situation. That means different things for different people, but it can include anything from lending a sympathetic ear, to talking through the problem, to making helpful suggestions, to simply reminding you that the experience is temporary and that you will in fact come down.

And the support app is not solely for those having bad trips. It can also be used by people having a positive trip who want to talk about their experience with someone.

The general idea about a bad trip is that using psychedelics will cause you lose your mind and probably die. How dramatic.

Most of the risks with psychedelics have to do with behavioral toxicity, not physical toxicity, explains Holland. If someone isnt properly prepared, educated, and supervised, the risks increase.

But the truth is, while bad trips most certainly can happen, their actual results are almost always much less dire.

While this can indeed be taxing, its almost never dangerous. And the fact is that the majority of people who experience bad trips report that they turned out to be beneficial. A third of respondents described their trip down the dark rabbit hole as the most meaningful experience of their lives.

It may be unpleasant or uncomfortable, but sometimes, deep, significant behavioral changes still occur, says Holland. Sometimes facing your fears allows you to work through them better than running away from them.

Bad trips are often nothing more than you facing something you probably needed to face in the first place. Its your opportunity to look at and perhaps address repressed traumas or even aspirations.

A trip doesnt have to stumble its way into the bad zone to impart psychedelic wisdom. Sometimes you enjoy the same enlightening conclusions via a truly blissful experience.

Your best bet is to lessen the potential for a bad trip altogether by considering your set and setting beforehand. In a nutshell, this means taking steps to provide yourself with the appropriate surroundings (enjoyable companions, beautiful scenery, safety, etc.) and a prepared mindset (lack of immediate distress, healthily nourished, awareness of the rigors of the psychedelic state, and so on).

The Fireside Project app is the first of its kind, and well likely see similar tools emerge as the psychedelic space develops. But what if youre experiencing the fear and you dont have your phone handy? Here are a few tips for soothing or even ending a bad trip:

Remind yourself that it will end. One of the most common causes of a bad trip involves a fear that it will never end. It will. Remind yourself that youve taken a powerful substance and that while it feels overwhelming at the moment, it will start to wane, and within a few hours things will feel much more normal.

Change your setting. It might be that all you need is a quick change of scenery. That might mean going for a walk or even just moving to a different room.

Have some food or water. It could be that youre simply hungry or dehydrated, or you just need the distraction provided by food. Youd be amazed at how much the simple process of peeling an orange can do for your situation.

Art it up. This can mean many things: Put on some music (or change what youre listening to). Watch a movie. Play an instrument. Draw or paint. Sing. Its almost impossible to have a bad trip when youre singing.

Your best chance of enjoying a positive psychedelic trip is achieved through preparation creating the right set and setting. But if the grimness does set in, just remember that its not the end of the world.

The techniques above can work wonders for alleviating the situation, and tools like the Fireside Project app can provide much-needed support.

If all else fails, keep in mind that your so-called bad trip might be exactly what you needed. Its quite possible that youll emerge from your psychedelic adventure with a new perspective that will help you moving forward.

Nick Hilden is a travel, fitness, arts, and fiction writer whose work has appeared in the Daily Beast, the Los Angeles Times, Salon, Mens Health, Thrillist, Vice, and more. You can follow his travels and connect with him via Instagram or Twitter.

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Psychedelic Drug Therapy: Tips and Support for the Experience - Greatist

Opinion: The Time for Disability Employment Reform Is Now Maryland Matters – Josh Kurtz

By Nicole LeBlanc

The writer, a resident of Silver Spring, is a disability policy and advocacy consultant.

As we enter Year 1 of the Biden administration and Year 2 of this nightmarish pandemic, it is now more important than ever that we pass meaningful reform that focuses on moving away from segregated settings to a world where paying livable wages and ending benefit cliffs is part of the new normal for all people with disabilities.

The COVID-19 pandemic has shined a bright light on the dangers of segregation and discriminatory employment practices like paying subminimum wage. In addition, it has highlighted the need to ensure that essential workers like direct support providers, retail and so forth, are paid decent wages for the work they do.

Many people with disabilities who are at high risk of catching or dying from COVID often work in jobs deemed essential. The practice of paying workers with disabilities subminimum wage based on their productivity has been around since the 1938 Fair Labor Standards Act under Section 14C. Many people of color compare 14C subminimum wage to slavery. 14C is one clear example of the systemic ableism that exists in our society. 14C subminimum was does not promote self-determination or support people with developmental disabilities in becoming self-supporting.

Lastly, segregated employment is system-centered not person-centered.

As we look toward the next 30 years of the American with Disabilities Act we need to raise expectations for all adults with disabilities and their families on the value of real jobs for real pay. The time is now for the Era of Low Expectation Syndrome to come to an end.

We must move to a world of high expectations and presuming competence and employability. Disability service system transformation can be exciting and scary at the same time, but its worth it.

Right now, the COVID-19 pandemic has given us the perfect opportunity to redesign our society and systems to be more inclusive of the rights and wants of people with disabilities. There are numerous bills in Congress that can support people with disabilities in achieving the American Dream of Competitive Integrated Employment often known as Real Jobs for Real Pay.

One bill of importance is the Raise the Wage Act that would raise the federal minimum wage to $15 an hour and end the practice of paying subminimum wage over five years. Another big bill is the Transformation to Competitive Integrated Employment Act that if passed would provide money to states to support them in moving away from outdated models that pay people with disabilities subminimum wage in sheltered workshops and other segregated settings.

In order for this to be successful it is vital that states invest in infrastructure to support disability provider agencies to develop person-centered employment programs that help get people with developmental disabilities jobs and careers in the community at minimum wage or higher.

One big piece of this is paying livable wages to direct support professionals and job coaches who play a major role in our success living and working in the community. People with disabilities, especially those who self-direct their services need staff stability in order to be successful living and working in the community.

In addition, we also need to create effective training programs on successful job coaching as part of our transformation to Real Jobs for Real Pay. Other major reforms we must focus on is overhauling the Social Security Disability Insurance (SSDI), Supplemental Security Income (SSI) and other public benefit programs to eliminate work disincentives that keep people with disabilities trapped in poverty.

As the minimum wage rises across the nation we are going to see more and more people with disabilities falling off the cash cliff. In other words, for a non-blind worker with a disability who works 25 to 30 hours a week at $15 an hour you will hit the SGA, or substantial gainful activity, earning caps of $1,310 much faster than someone who is blind. For the blind community, the SGA earnings limit is $2,190 for 2021.

An easy way to solve this problem includes eliminating all earnings limits and just treat SSI and SSDI as universal basic income. As a society we must face the reality that the economic cost of living with a disability is much higher compared to those without disabilities. A second solution would be to raise the SGA limit to the same level as the blind community and adopt the $1 for $2 benefit offset above SGA.

In the SSI program your income goes down $1 for every $2 you earn. Using the $1 for $2 offset in the SSDI program would allow people with disabilities to earn more money and not worry about falling off the benefits cliff so fast. This is especially important for people with disabilities who live on their own in cities and states with very high cost of living.

Getting rid of benefit cliffs will also go along ways toward reducing the stress and anxiety that comes with working part time with a disability as we move away from segregated work settings that pay people with developmental disabilities subminimum wage. In addition, many people with disabilities face barriers to achieving full-time employment ranging from stamina issues to attitudinal barriers like ableism in the business world.

In the area of work incentives we must expand what counts as an impairment-related work expense (IRWE). One area that is due to an overhaul is what counts as an IRWE in the area of transportation.

Currently you can only count taxis as an IRWE if you live someplace where there is no transit. If you live in a place where there is public transit you are expected to use it unless you get something from your doctor that says you are unable to use regular public transit and need Metro Access-also known as paratransit. Paratransit is often the only thing you can deduct as an IRWE.

In the last 10 years transit options have evolved to include Uber and Lyft ridesharing, and it is past time that our public benefit system allow taking Uber or Lyft to work as an IRWE regardless of what other options are available in our community. I say this because it is far too common for people to work in places that you can get to by car in as little as a 30- to 35-minute ride from home. However, when it comes to taking public transit or paratransit, the commute to and from work can often be 1 to 2.5 hours longer than it needs to be.

Many people with disabilities cant tolerate long commutes, especially for those of us with autism and other disabilities who get car sick or nauseous from being in vehicles in the backseat for long periods of time. Other work incentive reforms we need to expand on are deductions for medical and dental services not covered by insurance like someone with autism and anxiety being able to deduct things such as massage, acupuncture, dental care cost, alternative medicine, and the cost of independent direct support staff used during both work and nonwork hours.

I say this because many adults with autism without intellectual disability do not qualify for Medicaid home-community-based services and having access to job coaching and home support is vital to our success in the community. For young adults the student earned income exclusion should be expanded to age 29 from 22 so that more people with disabilities can attend college and training programs that may help them achieve greater economic stability outside of the traditional jobs typically done by people with disabilities like food, filth, flower and filing.

The silver lining of COVID-19 pandemic is that it provides us with a great once-in-a-lifetime chance to make the social safety net for the disability community truly person-centered by ending systemic barriers that prevent us from achieving true community inclusion and self-sufficiency without the stress of benefit cliffs.

The era where being disabled is like a full-time job must end. As allies and advocates we must fight harder now more than ever to make the lives of the disability community easier. In the long term, COVID-19 is going to create a larger population of people with disabilities and chronic health conditions due to the effects of long-haul COVID.

In my opinion, the impact of this pandemic virus feels similar to days of the polio epidemic era. It is my hope that we can use the lessons from this nightmarish pandemic to create a world more accommodating and accepting of disability as a society.

As the old saying goes, It shouldnt have to happen to you for it to matter to you. If we all live long enough, we will all join the Disability Club. Climate change and disability are not partisan issues nor should they be.

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Opinion: The Time for Disability Employment Reform Is Now Maryland Matters - Josh Kurtz

In a Rust Belt city split by inequality, people are battling for healthcare justice. The fight for change is a fight for their lives. – Online Athens

SYRACUSE Sequoia Kemp stood at the crossroads of health inequality, her mind on a painful past.

Beside her:the second-oldest public housing project in the U.S. Just above: one of New York states most prestigious teaching hospitals.

She took in the glimmering glass and sterile white facades of SUNY Upstate Medical University that tower over the blood-red bricks of the tenement buildings, home to mostly poor and Black people here in this Rust Belt city of not quite 150,000.

The two worlds a shining beacon of American medicines bright future and stark reminder of the nations racially unjust present are literally separated by an elevated highway that carved through the citys heart decades ago.

Today, the Interstate 81 viaduct is a mass of rusting steel, chipping green paint and crumbling concrete. It is a relic of the 1950s-era urban planning that displaced and economically ravaged generations of Black and brown Americans in favor of white flight to the suburbs.

Divided We Fall: The healthcare inequities in Syracuse, New York

From childbirth to COVID-19 treatment and vaccination access, Black communities in Syracuse and across the nation face inequality.

Robert Bell, Rochester Democrat and Chronicle

And it is an impossible-to-ignore symbol, many here say, of the divisions and inequalities that put the health and lives of people of color in dire jeopardy.

On this late spring afternoon, traffic buzzed as a Black girl skipped nearby along the project's sidewalk with a cloth doll,playing amid the acrid smell of exhaust and swirling dust fromconstruction work. A rush of memories had gripped Kemp, a 26-year-old Black woman, of a surgery she had as a teenager to remove ovarian cysts.

She remembered the month of searing abdominal pain as doctors delayed the procedure. She remembered her mother's pleas to expedite the surgery to ease her daughter's agony.

Sequoia Kemp, a certified doula, stands next to her sister and client while holding her new niece in the hospital.Contributed photo from Sequoia Kemp.

But mostly, Kemp struggled with the thought that racism marred the surgery. The unanswered questions have plagued her for years:

Would doctors have listened to a white woman and acted sooner?

Is a Black mother powerless to protect her child from medical harm?

Will I ever be able to have children of my own?

Theres just so many stories like mine and so much trauma, and so much healing our community has to do, Kemp said. And Im going to do whatever I can to be part of that.

Those stories of Black women emotionally and physically scarred during childbirth inspired her to become a doula to prevent it from happening to others. She has seen countless times how the health care system treats people of color differently. She carries with her the strikingtruth that Black women are three times as likely to die in childbirth than white women.

On this day, she wears a T-shirt that reads:Birth Work is My Resistance.

Kemp is not alonein her fight on the front lines of health justice, in this city beset by festering wounds of racial segregation and stunninginequality. There are agents of change on both sides of the divide, here in the heart of the city and high on the hill inside the halls of medical healing.

The struggle to find basic care: Sickle cell children are living longer than ever, but as adults they face challenges to get basic care

But the stakes are crystal clear. They are written on the faces of the expectant mothers Kemp helps, etched in the well-being of her own body, evident in the everyday discrimination that targets the people she loves.

It's a fight for the lives of women. For friends and her family. For herself.

The first thing most of my clients say, Kemp said, is I dont want to die.

In Syracuse and across the country, a new generation of activists and medical professionals many of them forged by their own health-related trauma are leading the charge to end the systemic inequalities that ensure Black, Latino and Native Americanlives are less healthythan white lives.

Here, they are the people pushing plans to tear down Syracuses highway system and seeking reparation. The roads' racially biased placement killed the American dreamof their ancestors, who fled the Jim Crow-era South only to find a Northern city being segregated by its own brand of discrimination.

Justice In My Town - Health Care Crisis 1

Deka Dancil, president of Urban Jobs Task Force, leads a I-81 march in downtown Syracuse.

They are also the medical students who are exposing untold and ongoing harm caused by attempts to justify American slavery with theories that Africans race was inferior to whites.

And they are the scholars unraveling the legacy of slave-owning doctors claiming Africans comparatively weak bodies benefited from grueling slave labor.

They are behind a growing movement to reject the racial inferiority theories, which remain in the bedrock of modern medicine despite being disproven and have fueled the mistreatment of generations of Black Americans.

Inequality in education: I dont think you are ready: Boys of color fell further behind at school amid COVID-19

July 16, 2021 in Syracuse. Pioneer Homes, the second-oldest housing project in the country is on the edge of Upstate Medical and Syracuse University.Robert Bell/Rochester Democrat and Chronicle

This movement is part of a much broader struggle to improve the quality of life for those excluded from the American social contract. When it comes to keeping people of color healthy and healing them when they are not endless factors play a role, from the environment to access to care centers, from insurance plans to steady incomes, from nutritious meals to medical mistrust built on centuries of trauma.

The health-justice movement aims to end racist housing policies that place more Black children near toxic fumes and exhaust, contributing to them having asthma-related death rates eight times higher than whites.

It requires eliminating food deserts and medical distrust linked to Blacks being twice as likely to die of diabetes than whites. And removing unjust economic policies and practices linked to Black people being 30% more likely to die from heart disease than whites.

The endeavor also targets the medical deserts and low-wage jobs linked to Blacks, Latinos and Native Americans put at twice the risk of dying from COVID-19 than whites.

Children play and pose for the camera at playground close to I-81 in Pioneer Homes on July 16.Robert Bell/Rochester Democrat and Chronicle

Racism is not just the discrimination against one group based on the color of their skin, Centers for Disease Control and Prevention Director Dr. Rochelle Walensky said in April, declaring racism a national public health threat.

Rather, it is the structural barriers that impact racial and ethnic groups differently to influence where a person lives, where they work, where their children play, and where they worship and gather in community, she added.

Undergirding it all is the tectonic push for truth in medicine, as revelations surrounding complex clinical algorithms used to make race corrections to treatments suggested millions of Americans were mistreated for decades.

COVID and race: CDC declares racism a 'serious public health threat' as COVID-19 puts a spotlight on disparities

USA TODAY Network journalists assembled a complex assessment of these intertwined issuesby interviewing Americans from across the country, revealing the lives devastated by health inequality, as well as their fight for better treatment. They also analyzed health data and federal records detailing the misuse of race in medicine to shed light on the massive systemic reforms needed to end disparity in health and health care.

The outcome of the heated debate among health care leaders over race-based corrections in particular could save lives and prove crucial to building trust with people of color.

More and more medical groups are realizing that race corrections are both on the wrong side of history and on the wrong side of evidence-based medicine, said Dr. David Jones, a Harvard University professor. I hope people of color would look at this and say doctors are really trying to look at this and figure out what is going on.

In Syracuse, which hassome of the poorest neighborhoods in the country, tales of unmet health needs, unsafe housing conditions and unequal access to health care unfold daily.

Deka Dancil grew up Black in extreme poverty, eating cheese slices and drinking hot sauce for days at a time when her familys food stamps ran out. She spent her teen years sleeping on couches at homes of friends and relatives and worked her way through high school as a janitor at Upstate Medical University.

Deka Dancil, of Syracuse, grew up in extreme poverty. She eventually graduated from Syracuse University and became president of the Urban Jobs Task Force.Robert Bell/Rochester Democrat and Chronicle

I would have never believed, or had the audacity to think, that if there was something I needed that I would be important enough for the top specialists at Upstate to care for me, said Dancil, 28, and now president of the Urban Jobs Task Force.

As a Medicaid patient, she added, her care was always funneled to the federally qualified health center, which lacked the expertise and resources available at Upstate.

Lily Sanders, a 67-year-old Black mother of three, grandmother of 11, and great-grandmother of four,has taken pride in working low-wage jobs at Syracuse-area nursing homes. But she's remained unable to afford health insurance premiums and deductibles most her life.

Instead, she has prayed to stay healthy and out of the emergency room, while living among the boarded-up Victorian homes and gang violence that have blighted the city for decades.

Its very scary. Ive been blessed with good health, and every day youre hoping that you dont need anything, Sanders said.

She described herself as one of the millions of working-poor Americans, earning above the Medicaid threshold but unable to afford health insurance costs. She has often turned to the Poverello Health Clinic, a free health center in Syracuse, for minor care while forgoing most dental treatment.

It affects people of color because they came from a place of zero from slavery, she said. You try to get something, but the system doesnt allow you to get anything…You just cant get a toeholdand you just never get up.

The preventable suffering is clear for Rachel Johnson, a 25-year-old community advocate, gently urging a Black man with diabetes to visit doctors and eat healthy. His diet consists mostly of offerings at the corner store advertising beer and cigarettes, rather than fruits and vegetables available at grocery stores in less poverty-stricken neighborhoods.

There is long-standing intergenerational trauma that is baked into people of color, said Johnson, director of health services at Syracuse Community Connections. Some of the bigger issues of mistrust in health care are connected to some of those historical factors.

Disparities in the US: COVID deaths third after heart disease and cancer in US last year; people of color hit hardest, CDC reports confirm

This is national. Its not just one local entity, or just one city … it is across the board, she added.

The I-81 viaduct separates Upstate Medical University, one of the best medical colleges in New York state, from the Pioneer Homes housing projects in Syracuse, New York.Robert Bell/Rochester Democrat and Chronicle

In Syracuse, the health inequity crisis has also manifested in the stunted lives of at least 675 children poisoned by lead paint in 2017 alone, many of them living in the citys aging housing stock still filled with lead-based paints that were banned in 1978.

Then there is simply the fact kids in Syracuse with asthma are more than twice as likely to end up in the emergency room than peers in surrounding suburbs, including cases linked to traffic-related air pollution from living in the highway systems shadow.

But life on this side of I-81 has helped prompt a push for change on the other side, where three Black women studying at Upstate Medical to become doctors have turned their personal clashes with discrimination into a collective attempt to achieve health justice in their town.

Eight-year-old IsabelleThenor-Louis saw racism unfold one evening through the window of her own home.

Her father had pulled his car into their driveway in the wealthy, and mostly white, Long Island neighborhood where they lived.A police car stopped on the street with its engine idling as the Black man, a doctor, slowly walked towards that house that officers wrongly assumed he couldnt afford.

Under the glare of racial profiling, Isabelle's dad entered the front door. He embraced his family, and a few tense moments crept past before the police sped away.

Isabelle Thenor-Louis is a student at Upstate Medical University working to become a hybrid physician-journalist.Robert Bell/Rochester Democrat and Chronicle

It left the first of many scars in a rising American familys struggle against racism.

Today, a 26-year-old Thenor-Louis recalled such episodes including a patient mistaking her father for a janitor as sparks that ignited her path to medical school.

Its one of those things that snowballed as youre growing up and you start to realize, OK, Im not really seen as someone of value, she said. As a Black woman, I saw it was really important to be part of the solution.

Her realization expanded recently after she complained of health and skin issues common among Black women during medical visits, only to be dismissed by white doctors. When she visits doctors now, she wears a sweatshirt emblazoned with the insignia of her alma mater, Brown University, to combat racial bias, implicit or explicit.

Its unfortunate that I feel like I have to put on all these physical qualifiers to show I have value and should be treated equally, Thenor-Louis said. Its almost like preparing to go to battle.

Today, she is working towards becoming a hybrid physician-journalist in the mold of CNNs Sanjay Gupta, hoping to improve the health of people of color while sharing their stories to the world to effect change.

Entering the medical field: Medical school applications surge as COVID-19 inspires Black and Latino students to become doctors

Yet her trials at getting this far underscored the challenges behind the shortage of doctors of color, which span a range of economic and social barriers to medical school.

While the number of medical school spots has increased by 27% since 1981 overall, just 13.7% of the medical student population is from Black, Latino, American Indian or Alaska Native communities. Thats despite these underrepresented groups composing 35% of the U.S. population. Meanwhile, just 3% of doctors nationally are Black women.

And while research shows people of color are healthier when treated by doctors of color, advocates have long stumbled in closing the diversity gap. An effort stalled by the burden of more than $200,000 in medical school debt on average and racially segregated educational opportunity.

The pandemics uneven toll in communities of color, however, may turn the tide. The suffering contributed to an 18% surge in medical school applications for the fall, according to the Association of American Medical Colleges.

Further, many of the aspiring doctors are people of color inspired to remedy the health inequalities laid bare by the coronavirus, as scholarship programs, educational outreach and free tuition initiatives seek to remove barriers to medical school.

The importance of closing the divide between the ranks of doctors of color and an increasingly diverse nation of patients struck close to home for Samantha Williams, another Black medical student at Upstate.

Born and raised in Syracuse, Williams moved to the suburbs as a teen with her mother, a widow, and two siblings. Her only ticket to studying medicine: a scholarship promoting medical school diversity.

She's faced many microaggressions as a Black woman in a predominantly white environment, she said.

Recently a campus safety alert had Upstate Medical students smartphones buzzing, warning of a stabbing in the public housing projects near campus. Williams overheard a classmate sarcastically declare, Classic Syracuse.

Its hard sometimes seeing people of privilege making statements like that, she said.

During another class, Williams found herself the only student raising her hand when a professor asked if theyve known a victim of gun violence, drawing snide looks from classmates.

The incidents were among many reasons Williams worked with Thenor-Louis and their classmate, Angelina Ellis, the daughter of Jamaican immigrants, to organize the Health Justice at Upstate conference in January.

The virtual event drew hundreds of attendees and focused on connecting medical students, doctors and Syracuse community leaders to pursue local projects to reduce health inequity.

I have the greatest hopes that people understand the communities theyre treating, Williams said.

In Syracuse, young students and community outreach workers are leading the charge for systemic change. And in some ways, the history of doctors misusing race in American medicine began unraveling in a Harvard lecture hall.

There, medical students began questioning methods used to adjust treatments based on a patients race. Several of the students turned to David Jones, a Harvard professor specializing in race, technology and the culture of medicine, to find answers.

The resulting medical paper, Hidden in Plain Sight,published in August in New England Journal of Medicine, would raise questions about flaws in race-based medicine that some experts say were harming people of color.

From left, Isabelle Thenor-Louis, Samantha Williams and Angelina Ellis, all medical students at Upstate Medical University, are promoting medical school diversity.Robert Bell/Rochester Democrat and Chronicle

Theres such a pervasive assumption in U.S. society and U.S. medicine that Black and non-Black people are different; I dont think anyone stopped to look twice, Jones said.

Its often the people who are new to a profession who are going to be alert to something that members of the status quo cant see, he added, praising medical students for opening the racial justice floodgates in health care.

Black medical leaders: Coronavirus magnifies racial inequities, with deadly consequences

The groups probe of medical race corrections detailed how complex health-related math equations and risk calculators contributed to unequal care for whites and people of color.

Due to the algorithms, many Black men and women may have received delayed or lesser care for kidney, heart and lung diseases, the research suggests, and women of color potentially received less-aggressive cancer screening.

Some Black and Hispanic women may have been improperly advised against pursuing vaginal birth after a cesarean delivery, exposing them to a serious operation while robbing them of a personal choice more widely offered to white women.

And race-adjusted treatments may have perpetuated health disparities, rather than resolving them, by directing more medical resources to whites than people of color, according to the research.

In other words, using faulty and biased health data potentially engrained the negative effects of racism and discrimination into the medical system.

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In a Rust Belt city split by inequality, people are battling for healthcare justice. The fight for change is a fight for their lives. - Online Athens

Alabama’s Amazon union fight and the South’s long, often racist, history with labor organizing – Reckon South

Workers at Amazons Bessemer warehouse could get the greenlight to hold a second union vote in the coming weeks, setting up another showdown between one of the worlds most valuable companies and its embattled employees.

In early August, the Atlanta regional office for the National Labor Relations Board said Amazon violated labor laws by interfering in Aprils union vote. Workers wanted to have more control over the companys fast paced environment and change the highly controlled environment where output and even breaks are timed.

Alongside its findings, the federal agency recommended holding another vote, a decision that now rests with the NLRBs regional office in Atlanta.

In coming to its decision, the NLRB said the evidence against the Jeff Bezos-founded company demonstrated that the employers conduct interfered with the laboratory conditions necessary to conduct a fair election.

Amazon said in a statement that the vote should stand.

Our employees had a chance to be heard during a noisy time when all types of voices were weighing into the national debate, said the statement. And at the end of the day, they voted overwhelmingly in favor of a direct connection with their managers and the company.

Having the vote overturned is a big step toward a potentially big win for Amazons employees and could become an impetus for improved workers rights across the country and in the South, according to Daniel Cornfield, professor of political science at Vanderbilt University and editor of the Work and Occupations academic journal.

This decision is an important victory and extends to workers beyond the South, said Cornfield, who added that the new pro-union administration in the White House likely affected the decision. Certainly, the actions of the president, as well as national politicians, and the NLRB can send a message to workers everywhere who are trying to unionize that they have the right to do so and that the employer must allow them to do so.

Despite raising its minimum wage to $15 an hour, Amazon has been the target of multiple unionization efforts. Amazon employees in Staten Island, New York, also recently lost a disputed unionization vote. The NLRB found that Amazon interfered in that May vote but has not made similar recommendations to hold another.

In response to Amazon, which is the one of the worlds largest private employers and has never lost a union vote in the U.S., the International Brotherhood of Teamsters voted in June to create a division that solely focuses on Amazon.

Unions in decline

In the past 60 years, union membership in the South and in the rest of the country has declined by about two-thirds, but while union membership is still relatively strong in some northern states, the continued erosion has left unions in the South on the brink. Since 1964, when the Bureau of Labor Statistics began keeping records, union membership nationally fell from just under 30% of all workers in 1964 to just over 10.8% last year, the lowest since records began.

In the South, around 15% of workers were unionized in 1964, falling to just over 5% today.

Because of that gradual slide and general anti-union sentiment, major manufacturers have increasingly identified the South as a place to do business often having the deal sweetened by lucrative fiscal incentives such as tax breaks, hard cash, and even free land.

Those enticements have brought in billions of dollars in investment to the South, ever since Nissan began pumping out vehicles in Smyrna, Tennessee, at the start of the 1980s. The plant heralded the start of a major foreign and domestic automobile manufacturing hub that today is present in nearly every Southern state.

Today, GMC has a presence in Texas, Kentucky and Tennessee. Ford has two plants in Kentucky, while Toyota has manufacturing plants in Alabama, Mississippi, Texas and Kentucky. The list of major automobile manufacturers goes on, with Honda, Mazda, Nissan, Hyundai, Kia, Volkswagen, Volvo, BMW, and Daimler all operating in the South.

But very few have a union.

Some of the plants have attempted unionization over the years, but most havent even tried. Even the successful ones have been held up by years of court challenges. The Mercedes plant in Vance, Alabama, has a union, but it required a federal appeals court to uphold the results.

But for every successful union, there are several failures.

Volkswagen workers in Chattanooga failed in their efforts back in 2014 and again in 2019 despite having executive backing, while strong words from former South Carolina Gov. Nikki Haley kept a union from forming at Boeing the same year. The NLRB accused Boeing of moving part of its manufacturing hub to the South in retaliation for past union strikes at its Seattle manufacturing hub.

That complaint was later dropped.

Among the biggest perks, however, are the low-cost workers, lack of regulations and a region where anti-union sentiment has been embedded in the psyche of workers and businesses since the end of slavery. But these companies have brought tens of thousands of well-paying jobs that typically pay above the area median, helping working class families in impoverished regions build wealth. While the costs involved in attracting major companies to do business in the South have often been high, the rewards are numerous.

Black and White

Unionizing in the South has a thorny history that, like so many other things Southern, can trace its complexities through slavery, race and politics.

In the aftermath of the Civil War, white dock workers in New Orleans, for example, competed with formerly enslaved men, who because of destitution and repression were still considered cheap labor, according to the book, Waterfront Workers of New Orleans: Race, class and politics 1863 1923.

The new competition evoked a racist reaction from white workers, who called for the deportation of their Black counterparts back to Africa. When Black workers formed a union in 1872 and attempted to integrate the white union, they were ridiculed.

We were scoffed at, said Black union president R.T. Matthews at the time, and rebuked by white men who work along shore, telling us constantly that the negroes broke the wages down, and it caused all to suffer.

The citys elite pounced on that racial division, using Black dock workers when white workers went on strike, and vice versa. The situation caused hostility and undermined union efforts for decades, noted the book.

That hostility echoed across the South and the roadblocks to Southern unions continued.

Not long after the end of World War II, the Congress of Industrial Organizations launched Operation Dixie, an attempt to increase union membership in the South. It was believed that raising wage levels among workers in the South would consolidate the huge wage gains won by unions in the North. The move was in part an attempt by Democrats to transform the conservative politics of the region.

Operation Dixie fell flat in part because of the Jim Crow laws at the time. Just like the dock workers of New Orleans 70 years before, racial divisions persisted, preventing white and Black workers from unionizing.

Southern unionization was dealt a further blow by the Taft-Hartley Act of 1947, which made it harder for unions to strike and is still in force today. The act was passed in the aftermath of the major strike wave of 1945 and 1946. Over those years, five million people went on strike, and included the biggest strike in U.S. labor history. Not long after that, the United States entered into the second Red Scare, a period of anti-communist sentiment that, among other things, tied unions with long-feared prospect of communism. Lasting a decade starting in 1947, the Red Scare saw laws passed that prohibited members of the Communist Party in America from holding office in unions and other labor organizations.

Today, the tactics used by corporations to deter unionization are vastly different. The NLRB official noted that among the tactics Amazon used to interfere with the Alabama union vote was pressing the U.S. Postal Service to install a vote card collection box near the warehouse entrance. The box was then covered in an Amazon-branded tent with cameras pointed at it. The NLRB said the setup gave the impression to workers that they were being monitored.

While Amazons workers in Bessemer will likely have another chance to be the first U.S.-based union within the company, it will still be a formidable task.

Large corporations can marshal tremendous legal resources to intimidate and scare workers, said Cornfield, who also said that the recent decision against Amazon shows how large corporations routinely act against employees. The important thing to think about with Amazon being charged with intimidating workers is very important for two reasons.

Its a very visible act which demonstrates to the American public that large corporations do act illegally to prevent workers from unionizing. And the other being that the public learn that large corporations do have tremendous capacity to dissuade workers from unionizing in legal ways. That educates the public and workers everywhere that perhaps the whole system of union campaign conduct is weighted in favor of the employer, especially these humongous companies that have tremendous resources to deter people.

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Alabama's Amazon union fight and the South's long, often racist, history with labor organizing - Reckon South

Jan. 6th fascism, monopoly capital, and working-class power – Communist Party USA

The January 6th rioters at the U.S. Capitol attempted to overturn the November election and restore Donald Trump to power. This collection of everyday Republican Party activists were members of white supremacist organizations such as the Proud Boys and Oathkeepers. The mob included off-duty police and military members, small business owners, and a grab-bag of conspiracy theorists associated with Q-anon and anti-vaccination groups and religious fundamentalists.

Angry that the majority of U.S. voters ended the dysfunctional rule of the Trump administration, they sought to help him frog-march the U.S. toward fascism.

Trump fueled this attempted coup with a ravenous appeal for violence at the Capitol leading up to the January 6th formal recording of the Electoral College votes. Evidence also shows that his loyalist Roger Stone likely coordinated with participants in the violence at the Capitol.

That days events were triggered by Trumps relentless campaign against the legitimacy of the November election, a predictable tactic in coup attempts. In his book Washington Bullets, author Vijay Prashad shows how the script works: coup plotters denounce the election and rile up their supporters to promote violence, provoking a military response to install the strong man to restore order. Media reports show that U.S. military officials feared that Trump aimed for this outcome and fought to limit military involvement toward this end.

That is how close we came to the installation of a fascist regime in this country.

Right-wing culture of conspiracy and trending fascism

The terroristic events of Jan. 6th were fueled by a culture of conspiracy that dominates the Republican Party. Republican Party boss Donald Trump didnt invent this culture of conspiracy, but he did exploit and transform it into a daily, relentless mantra. The original conspiracy theory deployed frequently by Republican Party activists, donors, and media personalities typically centered on Black control of the Democratic Party and its use of guilt and radicalism to undermine white supremacy. Conspiracy-style politics infused with racial hatred made Rush Limbaugh, Pat Buchanan, and Ann Coulter rich in the 1990s. This conspiracy theory has been at the heart of GOP attacks on affirmative action, school desegregation, and voting rights since the 1970s.

Donald Trump has always been a promoter of racial conspiracy and racist policy. He launched his campaign for president with manufactured racist claims about Obamas phony birth certificate but was too afraid of actually competing with Obama in 2012. His 2016 campaign demonstrated his effective ability to trumpet racist and sexist politics to his mass base, which made him a perfect fit for the Republican Party nomination.

He propelled these once-marginal claims into the daily reality of tens of millions of Americans, fashioning a new and dangerous political terrain.

In his book, How Fascism Works, Yale philosopher Jason Stanley argues that the systematic linkage of victimhood rooted in racial theories and xenophobia, the methodical attacks on intellectuals and scientific thought, the aggressive appeal to law and order and to the hierarchical power of the strong man and his party, and the relentless denial of truth and evidence to construct a mythology of racial supremacy are among the essential ideological-cultural features of a fascist party and regime.

Over the four years of his disastrous term, Trump soft-pedaled, even promoted right-wing militias, neo-Confederates, alt-right hipsters, and other assorted neo-fascist elements on the fringes of his party. He blended the Nixonian Southern strategy that appealed to suburban whites in coded language with frequent denunciations of political correctness as a violation of white peoples right to free hate speech. He frequently resorted to open appeals to racism (other forms of hatred) and pushed it to the center of his partys ideology with claims that immigrants from Latin America are criminals, that China deliberately spread COVID, that anti-racist protesters deserve to be shot or beaten, women leaders are detestable, that queer and trans people should be stigmatized, that doctors and scientists are part of a deep state conspiracy to undermine his presidency, and so on.

Much of Trumps two campaigns and his presidency were predicated on hatreds of racial minorities, foreigners, the poor, religious minorities, and their occasional allies a strategy that reflected and drew on fear. The neoliberal stage of capital, characterized by a deepening of exploitation to save capitalism from repeated crisis, has produced much anxiety for the 99%. But the incompetent billionaire offered no solutions to the rule of monopoly capital. Instead, he exploited the vulnerability of his Euro-American base under these conditions and tapped into their generations-long belief in their cultural and political superiority in the U.S. social landscape. He fed his narrowing base racist tropes, xenophobic lies, anti-Black stereotypes, and above all new permission to believe in conspiracy theories that elevated their own victimization at the hands of these others.

He deployed his campaign of conspiracy against all U.S. social institutions. Republican Party politicians and media personalities have frequently targeted the lame stream media, elite college professors, public schools, and activist judges for their wrath against imagined offenses. Trump borrowed this style and elevated it to a culture of conspiracy, hate, and retaliation. Even today Trump followers can be found lobbing threats of violence at public health officials who insist on necessary measures against the pandemic, professors who talk about critical race theory, or media personalities that frequently expose Trumps lies.

Racial cult of death

The culture of conspiracy translated into a cult of a willingness to die for Trump, as many on the far-right pledged during the pandemic and the 2020 election campaign. They believed his claim that the pandemic was a hoax and would vanish quickly, and even as 611,000 people in the U.S. have died, continue to call for resistance to scientific measures to protect their own health. Some insisted that freedom is more important than safety, though they are unable to answer who would be left to vote for Trump if they all expired from the illness.

A willingness to suffer for the sake of billionaire, racist politics is explored in a recent book by Heather McGhee titled The Sum of US. In it, she explores numerous historical examples where Euro-Americans follow this orientation to white supremacist thinking and action. She shows how whites appear willing to cause their own suffering, a diminishment of resources they have access to, if they become convinced that non-white people, foreigners, or religious others will also benefit.

New examples of this mentality in Florida, Texas, and Tennessee are only the most recent disturbing examples. In those states, Republican Partycontrolled governments have threatened to gut funding for public schools and universities if they teach historical concepts like racial slavery as a foundational feature of the U.S. or if they attempt to implement public health measures to protect student, families, teachers, and staff from COVID infection. In other words, supporters of Republican Party policy are willing to suffer from ignorance about their own history, exposure to a deadly infectious disease, and a further defunded public education system in exchange for owning the libtards.

Trumps love for the militias, the conspirators, the Neo-Confederates, their violence, the hateful language, and the relentless attacks on institutions that didnt share his objectives overlays his abuse of power and the law. The crimes for which he was first impeached only to be protected by a Republican-dominated Senate that openly indicated its refusal to conduct a fair trial were a scratch on the surface. Graft, financial corruption, abuse of campaign laws, abuse of corruption laws designed to separate government activities and campaigns, tax evasion, and systematic mismanagement of federal resources were rampant in the Trump administration.

Ways forward

The monopoly sections of the capitalist class, relieved to have apparently sidelined Trump at least temporarily without much more than a deadly riot at the Capitol, are struggling to reassert full control. They seem content to allow federal law enforcement to round-up rioters, hoping this move will restore sagging support for their racist system of mass incarceration. They are not interested in relinquishing white supremacy, even if it must be in its subtler forms, or class rule.

In the wake of the coup attempt, spokespersons for those sections of the capitalist class, including Joe Biden himself, have tried to elevate more reasonable voices within the Republican Party. The objective is twofold. First, they want to repair politics-as-usual to restore legitimacy to a political system disfigured by Trumpism and the pandemic, and nearly supplanted by the 2020 #BlackLivesMatter uprisings. Second, they despise the idea of discarding the Republican Party as a whole, as it would mean a default elevation of the left, labor, socialist, and communist forces and a further tilting away from the dominant neoliberal, racist-class policy of the past two generations.

Neoliberalism is a class policy of monopoly capital created in reaction to the civil rights/labor movement struggles of roughly 1930 to 1970 that dismantled Jim Crow, established the New Deal, built the U.S. labor movement, sided (sometimes) with the anti-colonial movements, and generally checked the absolute dominance of the corporations and white supremacist culture of the U.S. Neoliberalism is a set of anti-government, anti-public resources policies rooted in white supremacy (especially anti-Black hatred) that aimed to re-establish the ability of monopoly capital to accumulate based on working-class segmentation and super-exploitation. Privatization, debt-capital, global dominance of finance capital, destruction of civil rights victories (affirmative action, school desegregation, voting rights), racist mass incarceration, and frequent war and intervention was the price paid.

Studies of this period of history reveal some disturbing contradictory trends. Unionization rates collapsed after neoliberalism was launched, resulting in stagnating wages, exploding mass incarceration rates, and sky-rocketing poverty in Black and Brown communities. While public resources were systematically gutted to pay for tax cuts for the wealthy, social mobility and access to social goods diminished, sharpening social inequality. While corporate profits, shareholder dividends, and CEO pay ballooned, overall growth rates in capitalist countries shriveled. Simply put, the declining ability of capitalism to grow required new forms of extreme exploitation. These could be implemented only through battering the labor movement, fueling racist hatreds, and intensifying imperialism.

The socialist moment, the eruption of a disparate politics that is at least antithetical to the neoliberal agenda and at best a demand for working-class power and leadership of the country, emerged after yet another economic collapse in 20078. It has coincided with nearly continuous anti-racist uprisings from 2013 to the present, a massive democratic campaign to defeat Trumpian fascism, a deadly pandemic for which the ruling class has had few solutions, and more frequent and intense effects of capitalism-caused climate change.

The socialist moment its movements and campaigns have extracted some concessions from monopoly capital through the Democratic Party. Nationwide movements for a minimum wage increase, for voting rights, for workers rights, for public investments, for wealth taxes, etc., seem winnable, and even some Democrats appear to support many of these demands.

Growing the socialist moment into a permanent social force is necessary. More and more people need to understand why capitalism is doing to them what it is doing. They need to be organized in labor unions, democratic organizations, and working-class or socialist-oriented political parties. We need to train ourselves to understand the social forces arrayed against us, to learn effective anti-racist struggle, to fight for community and social closeness with all of our working-class family. We need to elevate democratic resistance to male supremacy and sexism, homophobia, and transphobia. Yes, we can make permanent Trumps defeat and build the movement to defeat monopoly capital.

Images: Jan. 6 riot, Blink Ofanaye (CC BY-NC 2.0); Unite the Right rally, Evan Nesterak (CC BY 2.0); Voting rights rally, SEIU (CC BY-NC-SA 2.0).

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Jan. 6th fascism, monopoly capital, and working-class power - Communist Party USA

Dangerous Illusions – The National Interest

AFTER MORE than six months in office, the Biden administration seems inclined to adopt the utopian vision of democracy promotion as a guiding principle of U.S. global strategy. This doctrine, or, if you prefer, persuasion, holds that America should, as far as possible, bend the world in accordance with the preferences of the United States and its largely European allies. Fortunately, President Joe Biden is a man of experience and pragmatic instinct. Whatever his impulses, he so far has been careful not to burn Americas bridges and, to the contrary, has taken steps to improve ties with key European allies, to restart dialogue with Russia, and to reduce somewhat the intensity of confrontation with China. Such tactical flexibility, however, does not change the fundamental direction of U.S. foreign policy, which at times is almost Orwellian in its tendency to emulate concepts of the former Soviet Union. It was a core belief of Vladimir Lenin and Leon Trotsky that the USSR, for its own security, could not tolerate the existence of the so-called capitalist environment. They assumed that capitalists would never accept coexistence with the new communist state and therefore rejected the status quo as an unrealistic option. Today, alongside the European Union, the United States has adopted the position that its mission is to promote democracy worldwide. Leaders in Washington regularly argue that if they fail to take up this mission, authoritarian governments will exploit American restraint and join forcesnot just to undermine American power, but to destroy democracy itself, depriving the United States of its cherished freedoms.

It is remarkable that this concept has become a key tenet of American foreign policy without any serious debate in Congress, in the media, or within the foreign policy community. At the heart of this approach is the presupposition that democracy is inherently superior to other forms of government, both morally and in terms of its ability to deliver prosperity and security. Democracy promotion is assumed to be a longstanding part of the U.S. foreign policy tradition rather than a radical departure from it. The Biden administration talks as though the world at largeapart from evil tyrantswill welcome its push for democracy and accept the self-evident righteousness of America and the European Union, rather than put up powerful resistance that may damage American security interests, American freedoms, and the American way of life.

YET DEMOCRACY does not have a stellar record throughout history. The best that can be said of it, as Winston Churchill once observed, is that under most circumstances it remains superior to all other tested forms of government. But for that to be true, democracy must be truly liberal, based on law, and include credible protections for minority rights. Such safeguards often are not taken. From its very conception, democracy has been marred by the original sin of slavery. Ancient Athens, the earliest known democracy, not only tolerated slavery, but was in fact founded on it. Citizens and slaves formed two sides of the Athenian political system. As historian Paulin Ismard writes, slavery was the price to be paid for direct democracy. Slaves allowed citizens to step away from work and to directly participate in government, attending assembly meetings and holding public office.

In the United States, the Founding Fathers similarly tolerated slavery, making its implicit incorporation in the U.S. Constitution. The constitutional concept of relations between the states presupposed the existence of slavery, and it required a civil war to bring about Abraham Lincolns emancipation of slaves in 1863. The Russian Empire remarkablyand without any bloodshedabolished serfdom altogether in 1861, unlike in the United States where slavery was, for the sake of political expediency, permitted to exist in some Union states until the end of the Civil War. Even thereafter, American democracy continued to deprive women and African Americans of the right to vote for several more decades. It is not self-evident that a democracy that limits political rights to a minority of white men is inherently so superior to a benevolent authoritarian state that possesses some elementary rule of law and embraces the concept of equal protection for its subjects. Contemporary examples include Russia under Alexander II, whose legal reforms introduced for the first time in Russia the concept of equality before the law, or Germany under Otto von Bismarck, who established the first modern welfare state by offering health insurance and social security to the working class. Closer to our own time, the enlightened authoritarianism of Singapores Lee Kuan Yew lifted millions out of poverty and maintained harmony in a multi-ethnic country.

UNTIL THE end of the Cold War, democracy promotion was not a constituent element of the U.S. foreign policy traditionthe term democracy does not even appear in the U.S. Constitution. The United States did not wage war to spread democracy, even in its own sphere of influence in the Americas. The NATO alliance, at its very inception in 1949, was directed squarely against the Soviet geopolitical threat and willingly embraced authoritarian members such as Portugal under Antnio de Oliveira Salazar, whom many considered fascist. Other American allies of the early Cold War period included South Korea and Taiwanneither of them a democracy at that time. Why did the United States ensure the protection of these non-democracies? It was to protect them from takeover by U.S. adversaries. In the process, this policy allowed American allies to have the freedom of choice, democratic or otherwise. After World War II, America positioned itself as the true leader of the free worldallowing nations with different interests, systems of government, and traditions to determine their own destiny.

The democracy promotion credo is, by contrast, quite different. It goes far beyond the protection of the international status quo and advocates an openly revisionist policy, one that is designed not simply to contain other top non-democratic nations but to change their systems of government. When it comes to major powers, profound transformations of this nature usually arise through internal change or outright military defeat; economic and diplomatic pressures alone typically do not accomplish that muchunless, of course, as in the case of Japan before Pearl Harbor, they trigger a war with clear winners and losers. The Biden administration does not talk about regime change, but its words and actions contribute to a suspicion in Beijing and Moscow alike that regime change would be precisely the result of yielding to American pressure. At a time when the United States is deeply polarizednot only over its foreign policy priorities, but over its fundamental valuespursuing such an ambitious, setback-prone foreign policy while simultaneously undertaking a transformational domestic agenda is reckless.

Most importantly, democracy promotion is unnecessary (at least on geopolitical grounds) because there is little evidence that China and Russia, when left to their own devices, would be eager to form a global authoritarian alliance. Neither power shows much inclination to view geopolitics or geoeconomics primarily through the prism of a presumed great democracy-autocracy divide. China seems perfectly willing to establish close economic ties with the European Union and, for that matter, even the United States. Chinese objectives appear quite traditionalgaining influence, developing friends and clients, without being particularly concerned one way or the other about their standard of liberty. Unlike the Soviet Union in the 1920s and 1930s, China isnt championing an international network of communist movements. When it comes to bullying neighbors, particularly in the South China Sea and beyond, Beijing makes little distinction between relatively democratic countries like the Philippines and autocratic ones like Vietnam. Despite the common challenge they face from the United States, Beijing and Moscow remain reluctant to conclude a formal political or military alliance. Their actual military cooperation goes little beyond largely symbolic military maneuvers and limited exchanges of military information. Both countries emphasize that they are aligned against the United States and, to some extent, the European Union, but they have not formed any meaningful alliance. China, for instance, did not recognize the Russian annexation of Crimea and even became the number one trading partner of Russian adversary Ukraine. Russia is likewise rarely reluctant to sell advanced military hardware to Chinas rival, India. It therefore remains a fundamental American interest not to create a self-fulfilling prophecy that pushes China and Russia closer together.

EVEN IN the relatively stable U.S. political systemwhere institutional safeguards have usually functioned under the most difficult circumstances, from Watergate to the Trump-Biden transitionit is widely agreed that foreign meddling is unacceptable. Why then do U.S. officials and politicians expect that China and Russia, without similar democratic legitimacy and without legal safeguards to protect their elites in case of defeat, are prepared to accept foreign interference in their fundamental internal arrangements? China and Russia are hardly natural allies, but this fact does not mean that the creation of an assertive alliance of democracies would not push a reluctant Xi and Putin together. The perception of an imminent common threat might force both leaders to conclude that whatever their differences in tactics, political cultures, and long-term interests, in the short run at least, they must work together to oppose the danger of democratic hegemony. If Xi Jinping and Vladimir Putin reach this conclusion, it will be increasingly difficult for them to speak to the United States with different voiceseven on issues where it would be perfectly logical in terms of their substantive interests to do so.

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Dangerous Illusions - The National Interest

‘Incidents’ author Harriet Jacobs crossed paths with Imogen Eddy, an early Harvard astronomer – Cambridge Day

The boardinghouse that Harriet Jacobs ran in the 1870s is now an apartment building at Mount Auburn and Story streets. (Photo: History Cambridge)

Harriet Jacobs, author of Incidents in the Life of a Slave Girl, lived in Cambridge in the 1870s. As historians have documented (including during a recent History Cambridge History Caf presentation), the boardinghouses she ran provided a home for Harvard students and faculty, as well as a sense of community for her daughter Louisa and friends.

Less known: Harriet Jacobs connection with one of the earliest female computers who worked at the Harvard College Observatory.

Jacobs used pseudonyms for the main characters in Incidents, the book she wrote based on her own life. She wrote affectionately about Mary Bruce, the baby she cared for after escaping slavery and reaching New York in 1842. Focused on reuniting her own family and fearful about maintaining her freedom, Jacobs still recognized that ere six months had passed, I found that the gentle deportment of Mrs. Bruce and the smiles of her lovely babe were thawing my chilled heart.

In real life, the baby was Imogen Willis. Her parents were then-superstar author Nathaniel Parker Willis and his first wife, Mary Stace. Mary Stace, whom Jacobs called a true and sympathizing friend, died in childbirth when Imogen was 3.

Fast-forward two decades. Imogen married a physician named William Eddy in 1865; they had a daughter in 1868. She may have envisioned a conventional life as a wife and mother, but circumstances dictated otherwise.

The 1873 Cambridge City Directory lists Mrs. I.W. Eddy (without her husband) living at 127 Mount Auburn St. the boardinghouse of Harriet Jacobs.

Keeping house

Harriet Jacobs boardinghouses offered a comfortable refuge to their residents. They also provided security for Jacobs. Like most Americans, she experienced transition and tumult during the 1860s. At the start of the decade, she left employment with the Willises; by then, Willis was remarried and had four more children. She published Incidents in the Life of a Slave Girl in 1861 after many years of attempts and near-misses. During the Civil War, she gained renown as an educator and relief agent helping freed people in the Union-occupied town of Alexandria, Virginia. After the war, she tried to open a school and orphans home for Black children in Savannah, Georgia, supported in part by financial contributions from Massachusetts, but racist sentiment proved too toxic to succeed.

Jacobs had lived in Boston in the 1840s and visited the area often, so she returned to a place where she had friends. In 1869, she laid out her own welcome mat after years of living in other peoples homes and boardinghouses. The 1870 Census identifies her as keeping house. Among the initial residents in her first house on Trowbridge Street were the Willises. A Willis son attended Harvard (Class of 1870), and his mother, sisters and brother moved to Cambridge, too.

The movement of the stars

Imogen Willis Eddys husband deserted his family. He worked as a physician in Nebraska and on two steamship lines out of New York City. She identified herself as a widow, which she officially was when he died in 1879 in Pennsylvania. Perhaps he sent money to her over the years; her will also listed a piece of property and life insurance trust that may have provided income. Her few surviving letters do not indicate poverty, but they do reflect that she felt pinched.

In 1889, at age 47, she applied for a job as an assistant at the Harvard College Observatory, the unusual employment opportunity described in The Glass Universe: How the Ladies of the Harvard Observatory Took the Measure of the Stars, by Dava Sobel. Observatory director Edward Pickering hired women to scrutinize the glass-plate images captured from the telescopes. From photographs (7,883 in 1890, with more added every year), the women determined the location, changes over time, relative brightness and other properties of thousands of stars. The job required math skills, patience and tremendous attention to detail. Not incidentally, female assistants earned 25 cents an hour, a wage few men with similar skills would accept.

Shortly after starting work, Eddy wrote to her brother, I should like very much to have you see some of my work on paper it sounds rather dry & stupid, but I am much interested in it. I never liked arithmetic but the higher mathematics and the problems solved by them, of the movements of the stars are quite another thing. I always read and studied everything I could find about astronomy and now I am daily learning more & more of the practical part of it.

Eddy did not make it into Glass Universe. When I contacted the author, however, she graciously introduced me to Maria McEachern in the John G. Wolbach Library and Lindsay Smith Zrull in the Anatomical Plate Collection at Harvard and the Smithsonian Institutions Center for Astrophysics. They are compiling often far-flung bits of information about the roughly 220 women who worked at the observatory from 1875 to 1975. Mrs. I.W. Eddy was one of the computers about whom they knew relatively little, and they were excited to learn about her backstory and connection to Harriet Jacobs.

Marked individuality

Harriet Jacobs and her daughter Louisa left Cambridge for Washington, D.C., in 1877. Although they were not in Cambridge when Eddy worked for the observatory, the Willis and Jacobs families stayed in contact. Over the years, they helped each other out in Washington and Massachusetts. In 1889, Bailey Willis wrote family members about Jacobs declining health: She is very lame and I presume she is slowly losing ground. She lived until 1897, age 82, when she was eulogized by prominent minister Francis Grimk as a woman of marked individuality.

Imogen Eddys daughter died in 1901, after a sad and lingering illness. (Her death certificate listed dementia as cause of death at age 32.) Eddy had siblings and their families to visit, but she lived in what sounded like a lonely rooming house on Acacia Street. Her work at the observatory gave her purpose until she died in a freak elevator accident in 1904, age 62. The headline on her obituary identified her as a Woman Astronomer.

Harriet Jacobs and Imogen Willis Eddy are buried at Mount Auburn Cemetery.

About Harriet Jacobs and Imogen Willis Eddy:

About the early women working at the Harvard College Observatory:

A special thanks to Maria McEachern and Lindsay Smith Zrull for providing useful links and background about Imogen Willis Eddys work at the HCO.

History Cambridge started in 1905 as the Cambridge Historical Society. Today we have a new name, a new look and a whole new mission.

We engage with our city to explore how the past influences the present to shape a better future. We strive to be the most relevant and responsive historical voice in Cambridge. We do that by recognizing that every person in our city knows something about Cambridges history, and their knowledge matters. We support people in sharing history with each other and weaving their knowledge together by offering them the floor, the mic, the platform. We shed light where historical perspectives are needed. We listen to our community. We live by the ideal that history belongs to everyone.

Our theme for 2021 is How Does Cambridge Mend? Make history with us at cambridgehistory.org.

Paula Tarnapol Whitacre is a writer and public historian in Alexandria, Virginia, where Harriet Jacobs lived during the Civil War. Whitacre described what Jacobs and abolitionist Julia Wilbur accomplished in Alexandria in A Civil Life in an Uncivil Time (Potomac Books, 2017), the first full-length biography of Wilbur. She is researching the intersecting lives of Jacobs and the family of Nathaniel Parker Willis. Her website, Discovering Lives, is at paulawhitacre.com.

Feature image: Harriet Jacobs formal 1894 portrait by Gilbert Studios via Wikipedia

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'Incidents' author Harriet Jacobs crossed paths with Imogen Eddy, an early Harvard astronomer - Cambridge Day

William Morris, Utopian Socialism, and the Value of Art over Numbers – lareviewofbooks

Anyone who has guiltily caught themselves wondering if pandemics are a bit like natural periodic fires is not alone. The devastation caused by human-driven climate change and the novel coronavirus together have revived outworn and discriminatory ideas about population. In November of 2020, The New Scientist reported readers suggesting that in the face of environmental crisis (including the incursions into wilderness increasing our vulnerability to zoonotic diseases), we should collectively be addressing the elephant in the room in other words, we must face the uncomfortable truth that there are simply too many of us: we are using up more resources than the planet can safely supply and paying the price for it; nature, in its tooth-and-claw indifference to individual suffering, is restoring the balance by killing a good number of us off. Given how tempting it is to bury our own culpability in speculations about natures greater wisdom, we cannot remind ourselves too often that one of the highest risk factors for severe illness and death from COVID-19 is poverty.

The idea that we can solve our problems by lowering our numbers resurrects a debate that began more than two centuries ago. In An Essay on the Principle of Population (1798), Thomas Malthus challenged the utopianism of Enlightenment thinkers such as William Godwin and Nicolas de Condorcet by arguing that population growth, which increases exponentially, will always outrun food supply until eventually it is checked by disease, famine, war, and other calamities. Widespread suffering among the poor, he insisted, was therefore not only inevitable but necessary. Moreover, public measures designed to alleviate such suffering only interfered with the natural corrections to population growth that ensured overall prosperity. In his revised 1803 editions of the work, he added that the indigent should be instructed to marry late to avoid overbreeding; if they ignored such advice then they should be blamed for their own misery. (This was incidentally an attitude mocked 74 years earlier by Jonathan Swift in his satirical proposal that the excessively fertile Irish poor should sell their children to the English as food.)

Aside from recent science-based projections that the human population is likely to fall over the course of the next century, what popular neo-Malthusianism chiefly ignores is global inequality. It is overconsumption in wealthy countries and carbon-greedy industry whose profits are reaped by multinational corporations not raw population density that leaves the biggest footprint and drives increasing interspecies contact. And yet for every YouTube video showing how the emissions linked to the voracious consumerism and wasteful habits of global northerners vastly outpace those of more densely populated regions in the Global South, there is comment after comment insisting that we are too many and that eventually nature will simply take her own course.

Malthusian ideas originated in an era of industrial revolution and empire building that seeded the problems of global inequality we now face. The modern analysis of how wealth is produced and distributed began, of course, with Adam Smith who is often erroneously described as the father of modern capitalism. However, that dubious honor belongs more properly to his younger contemporary, Malthus, who was himself a major influence on Charles Darwin.

Malthuss premise that any societys flourishing depends upon the natural, regular culling of its weakest members did not become a lasting principle of political economy, but it took root nevertheless in evolutionary science where it became the key to Darwins theory of natural selection namely, organisms whose traits give them an advantage in an environment will pass those traits down to their descendants, while organisms without such advantage will die before they reproduce. In a spirit even closer to Malthus, Darwins fellow evolutionist Herbert Spencer subsequently coined the phrase survival of the fittest, a cornerstone principle of laissez-faire capitalism, to explain how human societies grow and change. At the intersection of Malthusian economics and evolutionary theory, an essentially competitive human nature explains and justifies everything from jealous and acquisitive behavior to technological progress and unavoidable social inequality.

In Victorian Britain, such ideas were countered by those who railed against industrys exploitation of the poor and who described the tentacular reach of market capitalism across the earth and into the unhappy lives of the millions who suffered so that the few could profit. Charles Dickenss depictions of characters morally disfigured by the greed and cruelty characteristic of mid-century urban life are a good example of such protest. The social problem novels of Charlotte Bront, Elizabeth Gaskell, Benjamin Disraeli, and Charles Kingsley provide others.

But a very different kind of writing, revolutionary rather than reformist, and boldly turning away from social realism to the older genre of utopian romance, tackled these problems in another way. William Morris author, artist, textile designer, bookmaker, environmentalist, and socialist organizer believed that the creation and enjoyment of pre-industrial arts and crafts could undo the assumptions about natural inequality that were baked into capitalism. Influenced by both Karl Marx and John Ruskin, he demanded that works of art should actually embody the equality and freedom that had disappeared in an age witnessing the rise of mass production and excessive consumption on the one hand and widespread poverty and drudgery on the other. In News from Nowhere his novel-length description of an egalitarian, anti-consumerist society he aimed at nothing less than rewiring his readers minds and hearts.

News from Nowhere imagines a world two centuries into the future in which the miseries of the 19th century are all but forgotten. A few relics usually old books preserved by eccentric antiquarians draw a picture of that past. They tell a story of crippling poverty, brutal conditions for industrial labor including low wages, long workdays, urban pollution, poor public health, and a vast and unbridgeable wealth gap. Most of the lucky inhabitants of Morriss future London, however, simply take for granted the delights of what has become an entirely pastoral lifestyle. They have leisure to enjoy natures beauties, while contentedly engaging in just the right amount of healthy cooperative work outdoors or laboring happily over exquisitely decorated, hand-made objects which they give away freely to those who need them. They also enjoy remarkable longevity thanks to good food and an abundance of clean air and water. William Guest, the narrating visitor from the 19th century (and a thinly veiled stand-in for Morris himself), is the pivot between these worlds. While it seems at first like an impossible fantasy of return to an idealized medieval England, the story is less interested in depicting either the past or the future than in helping readers to recognize and reject the toxic Malthusianism of the Victorian present.

Admittedly, there are no direct references to population theory or even to Darwinism in the story. But the fact that there is no scarcity in Nowhere, and no scarcity because there is no greed, is a clue that Morris wrote the novel as a challenge to Malthusian evolutionism. For Morris, societies do not evolve out of deep evolutionary time, improving as they gradually eliminate their weaker constituents and sustained by the natural inequalities among their members. Nor are human beings fundamentally and naturally in competition with one another. Rather, he concurred with Marx, what we call human nature is simply the sum of the various circumstances that human beings themselves help to create and that in turn shape their lives or what Marx called the ensemble of social relations in the present.

News from Nowhere departs from an earlier tradition in utopian socialism represented in the schemes of Henri de Saint-Simon, Charles Fourier, and Robert Owen. Their utopian designs were based in a science of human nature to which they believed a planned community needed to be responsive if it was to produce social harmony and equality. The denizens of Nowhere, on the other hand, are good because they are the descendants of socialist revolutionaries. The whole reason they care about the happiness of their fellows, are sensitive to the skin and surface of the earth on which man dwells, have no interest in accumulating wealth, and put great value on the beauty of the objects they carefully craft is that they and their ancestors have built a new world free of the slavery and corrupting wealth gap of the commercial system. For Morris, as for Marx, that system was one of alienation where human beings have lost not only their sensuous relationship to the products of their own labor but the very capacity to shape their own lives and their relationships with others. The unalienated Nowhereans have replaced what their historian describes contemptuously as the competitive spur to exertion with an instinct for beauty and an impulse to share all that they enjoy.

The goal of the novel is to pass this along to its audience who must learn to read in a new way. For as one might expect, News from Nowhere is a little thin on plot: aside from a lengthy account of the revolutionary founding of Nowhere, the story consists mostly of a conflict-free journey up the Thames with a group of elegant and morally flawless Nowhereans. Yet it is the very lack of struggle and conflict that for Morris makes the story artistic in the true sense something that can be produced, shared, and enjoyed in a world endeavoring to rid itself of class discrimination and suffering. He believed that such art, because it was unalienated, could actively undo the devastating psychological effects of capitalism and thereby help human beings transform the oppressive conditions under which they lived.

Guest arrives in Nowhere in the year 2102. Scramble the digits and he would have landed instead in 2021 where of course in the real world his vision remains as utopian as ever, and where we can add to the alienation of wage labor and enormous social inequality the uncertain future of work in developed countries, the many ways that technology-hungry nations remain vectors of harm for poorer ones, globally uneven access to the COVID vaccine, and wide-scale climate-change injustice. What Morris reminds us, just as he reminded his 19th-century audience, is that these terrible inequities are neither natural nor inexorable. Imagining a perfect world in which we are transformed by art might seem trivial in the teeth of the massive problems we face. But In contrast to dystopian fantasies of population reduction, Morriss utopia suggests that through the shared appreciation of well-made things we may learn to relinquish the pleasures that bind us to others suffering.

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William Morris, Utopian Socialism, and the Value of Art over Numbers - lareviewofbooks

The Incarcerated Women Risking Their Lives to Fight Wildfires – Outside

On February 25, 2016, 22-year-old Shawna Lynn Jones died from a blow to the head by a falling boulder while fighting the Mulholland Fire in Malibu, California. She was part of Malibu 13-3, a 12-person crew of inmates who work as firefighters under supervision of the California Department of Corrections and Rehabilitation and the U.S. Forest Service. A Los Angeles Times article about her death stated that Jones was the first woman and just the third conservation camp inmate to die since the program began in 1943. Just is quite the word to use in such a sentence, considering the cruelty of the system that led to Joness death. In her new book Breathing Fire, writer Jaime Lowe offers a vivid picture of the injustices that affected Jones and her fellow firefighters.

Expanding on a 2017 feature she wrote for The New York Times Magazine, Lowe examines the fallout from Joness death and tells the story of the thousands of women inmates who help fight Californias wildfires every year. Male inmates have been firefighting since 1946, and women were given the option to do so in the 1980s. Public officials considered this a matter of fairness, Lowe writes, and in fact incarcerated women also tend to see the firefighting work program as a desirable alternative to the inhumane conditions of prison. The compounds that house inmate firefighters, called conservation camps,have better food and living conditions than the states prisons, and they offer participants the chance to earn credits that go toward shortening their sentences. In the book, Lowe describes getting to know many incarcerated firefighters who tell her the work has changed their lives for the better or that theyre hoping to get jobs in firefighting or forestry when theyre out.

But Lowe makes a clear distinction between professional firefighting in the free world and the carceral systems employment of inmates as firefighters. All the women I spoke with could see the benefits of the firefighting program, but most bristled at the idea that they had volunteered, Lowe writes, citing the litany of reasons an inmate would consider such a dangerous job more desirable than the conditions in prison, which include sexual assault, neglect for the sick or mentally ill, and poor nutrition. Volunteer is a relative term for the incarcerated.

And for all the comparative perks, offering wildland firefighting as an alternative prison experience is certainly not a much more humane way to treat prisoners. Inmate firefighters are paid a salary of just five dollars a day, which includes the 24-hour periods when they are on call for fires, plus one dollar per hour when actively firefighting. They work on the ground as hand crews, hiking in to clear vegetation early on in the fire and mopping up by stomping out embers at the end. Basically, the hand crews are the ones in the trenches, a camp commander named Keith Radey tells Lowe, and theyre mostly made up of inmate crews. Depending on the year, inmates might make up as much as 30 percent of Californias wildland firefighter crews. And while program spokespeople emphasize that inmates are considered just as capable as professional firefighters, they never train with live fire. Many of the women recount how scared they were to see a real fire for the first timewhile fighting it. In a striking scene, as a particularly erratic fire barrels toward one inmate crew, their foremen tell them that theyre seeing action that most free world firefighters never see.

Lowe spends a couple of chapters tracing the history of the fire program back to the ugly roots of Californias carceral system and slavery practices. The countrys first female firefighter, for example, was a Black woman named Molly Williams who worked as a servant for the man who had once enslaved her. The man was part of a volunteer firefighter corps, and Williams sometimes stepped in for crew members during fires. Historians often frame Williamss 19th-century heroism as entirely voluntary, despite the questionable power dynamics of her situation. In the 1900s, inmate labor drove the westward expansion of Los Angeles and the construction of the Pacific Coast Highway. More recently, women and people of color have been particularly affected by the war on drugs and three-strikes laws (still in effect in California) that give repeat offenders sentences of 25 years to life; the number of incarcerated women in the U.S. increased more than 750 percent between 1980 and 2019.

As the inmate population in California has grown, the number of incarcerated firefighters has too, doubling from the 1960s to today. And officials have never been coy about the reason; many have lauded conservation camps as cost-effective solutions to prison overcrowding and fire management. Because its so much less expensive than hiring more firefighters at a fair wage, the California prison systems forestry program saves taxpayers about $100 million a year, and has saved the state $1.2 billion since its inception. In 2014, the office of Californias Attorney General (then led by Kamala Harris) argued against reducing the number of inmates in state prisons because it would severely impact fire camp participation in the middle of a difficult fire season and severe drought.

Whether or not the women have had a positive experience at the conservation camps, most of their stories amply illustrate that the U.S. carceral system is not built for justice or protecting inmates. Even the women who love the program so much that they want to become firefighters when they get out of prison will likely be barred from many of those jobsor at least required to jump through lots of hoops to applybecause of their felony convictions. In 2017, Lowe met a woman at a conservation camp named Alisha, who told her that she was already taking classes in hopes of getting a job on an engine when shes out. In 2020, when Lowe told Alisha about a new law that makes it slightly easier for former inmates to get firefighting jobs, Alisha said, Oh god, thats so dope. I wish I was out. By that time, shed been given a life sentence after an attempted robbery, because it was her third offense.

Lowe, who began reporting this book in 2016, excels at detailing the injustices that make up these womens lives. She spends much of the book following a handful of womens stories from childhood to arrest to conservation camp. It seems wise to devote so much space to this level of personal narrative; in recent years Californias women inmate firefighters have seen no shortage of press coverage, much of which treats the program as a novelty or discusses it in broad, statistical strokes. Breathing Fire brings nuance to the lived experiences of the women inmates who are helping the state face an increasingly grim future of wildfire, and to Jones, the first of them to die on the job. But it never losessight of the central truth: they should never have been asked to do this in the first place.

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The Incarcerated Women Risking Their Lives to Fight Wildfires - Outside

Improve Your Online Privacy With These Seven Tools – Honk News

As the Internet continues increasing in size, it becomes more and more difficult to remain anonymous and safe online. Privacy concerns are growing larger among users, especially since companies such as Google, Microsoft, Apple, and others arent doing anything to improve that experience.

Fortunately, as a user, you arent left completely empty-handed there are still certain precautions that you can take. The following seven are some of the most important ones.

One of the primary ways through which everyone accesses the Internet is, of course, a web browser. However, while convenient and fast, the most popular ones such as Chrome or Firefox leave you fully exposed.

Tor is a browser bundle that aims to make you as anonymous as possible, by routing your connection through various different relays and sources. Ultimately, it makes you untraceable to the average person, but it will throttle your Internet speed by a significant amount.

Facebook Messenger, Viber, WhatsApp three of the most popular apps for instant messaging. Of course, they also dont put in a lot of effort to prevent your data from leaking.

On the other hand, the Signal app uses its own protocol that combines three different cryptographic algorithms in order to achieve maximum security. Alongside texts, images, and other media, Signal also supports end-to-end encrypted group chats.

The code which Signal uses for encryption is open-source, which means that its been thoroughly tested and scanned for any potential vulnerabilities.

Read More:Evangelion:3.0+1.01 Thrice Upon A Time- A Perfect Ending Of Famous Anime!

Unlike Google Drive and other storage services meant to help you free up space on your PC, Carbonite advertises itself as an online backup service. The process is extremely straightforward, and you can choose to back up any amount of data from a single file to the complete data on your PC.

However, since its easy to use, there arent a lot of customizable features left. Carbonite has been developed with safety in mind, which is why backing up and restoring files can take a long time. Still, these disadvantages are justified by the robust systems in place.

If youre wondering how ads manage to be so personalized, the answer is through analysis of emails. Whether you like it or not, Google sells your data to other companies so that they know exactly what youre interested in.

ProtonMail is an online-based email service that is cross-compatible with any other platform and has a very familiar user interface. What separates it from other similar services is zero access encryption, which means that not even the company itself can decrypt what youre sending.

In addition, it doesnt require any personal information and its basic version is free to use.

Using a regular web browser and its save password feature is a recipe for disaster. An experienced hacker only has to gain access to your browser, at which point all of your accounts are compromised.

Unfortunately, it can also be very difficult to remember dozens of different complicated passwords. 1Password is a password manager that keeps all of your keys under a singular, master password.

Not only is it safer, but it will also make your life easier since youll be able to log into different websites with a single click. Youll still have to remember that one password, but that shouldnt be too difficult.

Read More:Iron Man 4: Robert Downey Jr. Confirmation News Regarding The Movie

If you like the concept of the previously mentioned Tor Browser, but you want to keep using Chrome or any other traditional browser, then NordVPN is a solution for you. This software acts as a tunnel between you and the Internet, masking all the incoming and outcoming traffic from any third parties.

Unlike Tor, it wont have multiple masking spots only one. While this provides lesser protection, it wont throttle your Internet speed as much if thats important to you.

Identity fraud is one of the largest dangers on the web. It can leave long-lasting consequences and cause significant financial damage, especially if the attacker gets access to all of your compromising data.

While its important to be vigilant at all times while online, Spokeo Protect adds another layer of protection that you wouldnt have otherwise. By using it, youll be able to safeguard your credit, Social Security Number, medical insurance, and much more.

Maguire Haigh is a marketing manager for Spokeo. He is interested in the latest technology trends, marketing strategies and business development.

He also prefers traveling, exploring the world and meeting new people. Maguire has great experience in creating and editing articles on different topics.

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Improve Your Online Privacy With These Seven Tools - Honk News

Nanotech opens up job options in variety of industries – BL on Campus

The word nano refers to the length scale (one nanometre is one-billionth of a metre) that is one thousand times smaller than the micro scale, the scale that was traditionally associated with the electronics industry. Viruses and DNA are examples of natural objects on the nano scale; in contrast a human cell can appear enormous.

The term nanotechnology refers to the engineering, measurement and understanding of nano-scaled materials and devices. Manipulating matter atom by atom and creating features on the atomic or nano scale is now a proven technology and there is an ever growing catalogue that utilises nanotechnology.

Nanotechnology represents an entire scientific and engineering field, broadly within Materials Science and Engineering, and not just a single product or even group of products. As a consequence of this there are several different types of nanotechnology, and many applications associated with each type. There are also several other types of nano-sized objects which exist in our environment, both natural and unnatural such as films and coatings, embedded nanotechnology, biologically natural, biological nanotechnology, natural particles, manufactured particles, nano-electrical mechanical systems.

Building on current nanotechnology-enabled applications in areas as diverse as consumer electronics, medicine, energy, water purification, aerospace, automotive, infrastructure, sporting goods, textiles, and agriculture, the nanotechnology research underway today will enable entirely new capabilities and products. Nanotechnology also underpins key industries of the future. For example, new architecture and paradigms exploiting nanotechnology are providing the foundation for artificial intelligence (AI), quantum information science (QIS), next-generation wireless communications, and advanced manufacturing.

While advances in modern electronics have long been at the nanoscale, new nanomaterials and designs will ensure the continued strength of the semiconductor industry, which powers computing, e-commerce, and national security. Nanotechnology also enables the rapid genomic sequencing and sensing required to advance medicine and biotechnology. Nanotechnology R&D has enabled early detection of emerging diseases and will lead to the treatments of the future. Past investments in nanotechnology research and development have provided a foundation to support the response to the Covid-19 pandemic. Nanotechnology-enabled applications include vaccines, sensors, masks, filters, and antimicrobial coatings.

Examples of nanotechnology innovations are: a highly sensitive wearable gas sensor; nanoparticles absorbed by plants to deliver nutrients; durable, conductive yarns made with MXene; electrodes that incorporate nanoparticles and enable the conversion of sunlight to hydrogen fuel; nano-engineered pores in a membrane for water filtration; drug-loaded nano particles carried by red blood cells; and the first programmable memristor computer, enabling low-power AI applications. Nanotechnology advances are impacting a variety of other sectors including consumer electronics, aerospace, automotive, infrastructure, sporting goods, and agriculture.

Research Infrastructure

The research infrastructure, including physical and cyber resources as well as education and workforce development efforts, is critical to support the entire funding ecosystem (National Nanotechnology Initiative), and agencies will continue to invest in these important areas. Agencies use a wide variety of mechanisms to support the research infrastructure, including Centre grants, instrumentation development or acquisition programmes, training grants, fellowships, and collaborative programmes that support workforce development.

Career opportunities

The scope and application of nanotechnology is tremendous. Indian engineering and science graduates are increasingly opting for nanotechnology. Right from medicine, pharmaceuticals, information technology, electronic, opto-electronics, energy, chemicals, advanced materials to textiles, nanotechnology has its applications. Nanotechnology provides job opportunities in health industry; pharmaceutical industry; agriculture industry; environment industry; food and beverage industry as well in government and private research institutes.

Skills

One needs to have a diehard passion for research, especially to find out new structures in the field of nanotechnology. It is important to have sound analytical skills, along with a scientific bent of mind. Analysing and interpreting skills are a necessity in this field and also to accept failures in experiments as a challenge. Other necessary skills which are required are: Good mathematical and computer programming skills; adequate laboratory training for expert handling of advanced equipment; ability to learn and adopt new techniques; have a systematic way of working; a natural propensity for research work; keep track of the latest scientific news, books and research magazines; a good background of physics, chemistry, medicine, electronics and biotechnology

Job Prospects

A lot of job opportunities and a research career exists in the areas of nano-device, nano-packaging, nano-wires, nano-tools, nano-biotechnology, nano-crystalline materials, nano-photonics and nano-porous materials to name a few. It is estimated that around three million nanotechnology skilled workforce will be required worldwide by 2021. Many government institutes and Indian industries have focused on nano-materials. It is also estimated nano-technology will create another five million jobs worldwide in support fields and industries. A professional in the field of nanotechnology can easily find lucrative jobs in most of fields.

Since nanotechnology is a special branch that essentially combines physics, chemistry, biology, engineering and technology, it is opening up job prospects for students specialising in these subjects. The career opportunities in the fields of nanoscale science and technology are expanding rapidly, as these fields have increasing impact on many aspects of our daily lives.

A professional in the field of nanotechnology can easily find viable career opportunities in various sectors. They can work in the field of nano-medicine, bio-informatics, stem cell development, pharmaceutical companies, and nano toxicology and nano power generating sectors.

The major areas for the development of applications involving nanotechnology are medical and pharmaceuticals, information technology, electronics, magnetics and opto-electronics, energy chemicals, advanced materials and textiles.

Nanotechnology has varied applications in drug delivery to treat cancer tumours (without using radiotherapy and chemotherapy), solar energy, batteries, display technologies, opto-electronic devices, semiconductor devices, biosensors, luminous paints, and many others. A major challenge in this emerging field is the training for a new generation of skilled professionals.

An abundance of job opportunities awaits candidates with an MTech in Nanotechnology from India and abroad. Indian industry has focused on nanomaterials and many scientific institutions have started research and development activities in the field. The CSIR has set up 38 laboratories, across the country, to carry out research and development work in this field. Those with a PhD in Nanotechnology will have vibrant opportunities in the R&D sectors.

It is a perfect career for those who have a scientific bent of mind and a passion for studying and experimenting with the minutest molecules. Students with a science and engineering background and even mathematics with a physics background can pursue Nanotechnology as a career. Candidates with MTech in Nanotechnology are in great demand both in India and abroad.

(The writer is Associate Professor, Department of Physics and Nanotechnology, SRM University)

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Nanotech opens up job options in variety of industries - BL on Campus

Challenges and Successes of Dealing with COVID-19 in India | RRTM – Dove Medical Press

Introduction

The World Health Organization (WHO) affirmed COVID-19 as a pandemic on 11 March 2020 but earlier to this the Chinese government confirmed the first outbreak of Coronavirus disease 2019 (COVID-19) in Wuhan on 31December 2019. The state-wise lockdown, which was imposed in India due to the second wave of the novel coronavirus pandemic, affected people belonging to every economic stratum. In India, till now (9 July 2021), there have been 30,752,950 confirmed cases of COVID-19 with 405,939 deaths reported to the WHO. COVID-19 cases are rapidly rising globally of which the first case was registered on 21February 2020 in Italy. Meanwhile in India, case numbers have risen, and community transmission was officially declared by government in October 2020. Life is deeply affected by COVID-19 even for the ones who are not infected as isolation, contact restrictions and economic shutdown have changed the social and economic scenario of India. Vast populations and crowded settlements have increased the number of cases in China, Europe, USA and India. Countries with dense populations and robust travel history will increase the problem of decision-making authorities if testing is limited or disproportionate. The WHO has made projections of 3.5 beds per 1000 population1 but many countries have only 1.3 beds per 1000 population in hospitals which is again the concern of government. As the pandemic is growing in stages, this review assesses the prospects these stages might have on the Indian population as it highlights some key challenges for treatment and research related to antiviral drugs.

Cases were initially spread by migrants, overseas visitors, and some others who were in contact with these infected persons, and to control this spread lockdowns were called by various countries including India. The situation seemed to be under control due to the lockdown, but due to a religious gathering in New Delhi, which led to the human-to-human transmission of COVID-19, a sudden horrific increase in COVID-19 cases occurred. Initially, most individuals who came into contact with such infected individuals were unaware of the effects of the virus in their bodies. To sustain the countrys economy, unlocks were called by the Indian Government in multiple phases, therefore, the persons who were unaware that they were carrying the virus spread it many more healthy persons. However, preventive measures including social distancing, quarantine and isolation techniques had been taken globally and have proven effective in the absence of drug treatments and other approaches. Adults (ages 50 and over), and people with comorbidities can have higher chances of becoming severely ill with COVID-19 and contribute to the largest portion of all deaths worldwide among infected cases.2,3

In India, the overall numbers dying constantly increased, amongst them a lot of the demise circumstances pointed to a particular age-group of aged folks.4 In India, among the total COVID-19 cases (30,752,950) and total deaths (405,939) till 9 July 2021, 90% were older than 40 years. Overall, people in the age group of 40 years and greater, have suffered the major impact of the current COVID-19 eruption and are more vulnerable.5,6 The massive loss of people in the workforce is likely to have devastating social and economic consequences.

The basic measures adopted worldwide include maintenance of hand hygiene, avoiding close contact, using face masks, disinfection and monitoring health.7 The ongoing COVID-19 pandemic has once again brought the benefits of appropriate hand hygiene (hand washing and use of alcohol-based hand-sanitizers) to the centre stage. Since hand washing is not a feasible and available option at all times, the use of alcohol-based hand-sanitizers (hand rubs) has been recommended by health organizations, when hands are not visibly soiled. These sanitizers act as a powerful, fast acting and effective solution with broad antimicrobial range.7 Hands act as a medium for exchange of microbes between the organism and its environment. The skin of the hands harbours a variety of organisms ranging from commensal to potential pathogens. Therefore, adequate hand hygiene can greatly reduce disease transmission. The most commonly used agents for hand disinfection are hand-sanitizers. There are two major types of preparations available: alcohol-based and alcohol-free. The alcohol-based ones, known as alcohol-based hand rubs (ABHRs), typically have ethyl alcohol (ethanol), isopropanol, or n-propanol at concentrations between 60 to 95% alcohol.8 The alcohol-free preparations usually contain quaternary ammonium compounds (benzalkonium chloride or benzethonium chloride). However, these have been found to be less effective and have a risk of contributing to antimicrobial resistance (AMR), hence are not recommended by CDC.

The CDC has recommended the use of ABHRs and hand washing to fight the COVID-19 pandemic. This is due to the structural characteristics of coronaviruses, which are enveloped viruses with lipid bilayer and are easily inactivated by alcohol. A combination of factors such as inappropriate formulations, excessive/repeated usage of hand sanitizers during this pandemic will have far reaching consequences. These may range from emergence of situation like alcohol tolerance and antimicrobial resistance (AMR), disturbance of normal microflora, and product toxicity. Similar to antibiotics, excessive or repetitive application of alcohol through hand-sanitizers has the potential to act as a selection pressure for the emergence of new microbial species tolerant to high alcohol concentrations.9

Taking note of the repetitive use of ABHRs, Professor Tim Stinear from the Peter Doherty Institute for Infection and Immunity remarked

Anywhere we repeat a procedure over and over again, whether its in a hospital or at home or anywhere else, youre giving bacteria an opportunity to adapt, because thats what they do, they mutate. The ones that survive the new environment better then go on to thrive.

He further added that the risk increases when appropriate guidelines are not followed.10

Eliminating the normal microflora of the skin by repeated use of hand-sanitizers may eventually deprive the skin of the protection offered by these commensals. Long term use of personal protective equipment along with frequent hand hygiene was responsible for high rate of skin damage in 97% of respondents while frequent hand hygiene was attributed with increased risk of hand skin damage.11

The world has joined hands with parallel efforts for the production of vaccines in opposition to COVID-19 pandemic.

A densely populated area like Ladakh has set an example for implementation in the Guidelines for hygiene and sanitation during the era of COVID-19 pandemic by setting up Foot-Operated Washing Station, implemented at the Indian Astronomical Observatory (IAO), Hanle. Having one of the worlds highest located sites for optical, infrared and gamma-ray telescopes operated by the Indian Institute of Astrophysics (IIA), Bengaluru, IAO12 has one in all the worlds highest set sites for optical, infrared and gamma-ray telescopes.

Antiviral nano-coating and new nano-based material for use in Personal Protective Equipment (PPE) was invited by The Department of Science and Technology (DST) using the Science and Engineering Research Board (SERB) portal, scale up for which could be done by partnering industry or start-up. India could be supported greatly by such nano-coatings technology to fight against COVID-19 pandemic. N-95 respirator, PPEs kits and triple-layer medical masks could be prepared from antiviral nano-coatings for safeguarding healthcare workers.13

Patients that showed flu-like symptoms was screened and detected for COVID-19 through indigenous company Mylab Discovery Solutions through the development of PCR-based molecular diagnostic kit.

TDB will try to boost the production process of kits so that present capacity could increase from 30,000 tests per day to one lakh tests per day. This automation by company could be achieved within the next few months. Considering the national emergency COVID-19 kit will be deployed by ICMR and CDSCO.14

As the demand increased, production of sanitizers have seen a boom amid coronavirus outbreak. Owing to which alcohol-based herbal sanitizer was developed by NBRI under Council of Scientific and Industrial Research (CSIR)-Aroma Mission as per the World Health Organisation (WHO) guidelines. Apart from having 60% of isopropyl alcohol for killing germs it has essential oil from Tulsi as natural antimicrobial agent. It is not only last for 25 minutes but also prevents skin from dehydrating. Herbal sanitizer has been found to be effective against the pathogen (Staphylococcus epidermidis).15

The Council of Scientific and Industrial Research (CSIR) is leaving no stone unturned in the battle against novel coronavirus. Repurposing of existing drugs is one of the strategies deployed by CSIR. The Council is implementing this strategy by evaluating an existing drug (Sepsivac, that available commercially) that is used for treating gram-negative sepsis patients. Both Gram-negative sepsis patients and critically ill COVID-19 patients, exhibit the altered immune response and a massive change in the cytokine profiles. Cytokines are produced in response to an infection and they are essential for host defence against pathogens. There are six types of cytokines, which belong to different families and the mixtures of cytokines, called cytokine profiles. One of the significant contributors to death by COVID-19, has shown the heightened immune response, called a cytokine storm. The immune system starts attacking both infected as well as uninfected cells and unable to discriminate between a friend and a foe, leading to tissue damage which resulting in sepsis. This drug (Sepsivac) modulates the immune system of the body and thereby inhibits the cytokine storm leading to reduced mortality and faster recovery.16

ICMR releases advisory for use of Cartridge-based Nucleic Acid Amplification Test (CBNAAT) using Cepheid Xpert Xpress SARS-CoV-2, effective from 19 April 2020.17

Indias first antibody-based testing kit was developed by NuLife Consultants and Distributors Pvt. Ltd, New Delhi which takes only fifteen minutes to yield accurate results. It is launched in two weeks and regular production has also started it was approved by the Indian Council of Medical Research (ICMR).18 The new finger prick kit will provide adequate access to cost-effective testing.

Home screening test kit for COVID-19 was launched by Bione with easy-to-use kit displays after approval from the requisite medical regulatory authorities.

In a get through development, the Company has devised the screening kit which can provide respite from the impending fear of the contagion. It will foster timely detection of the disease while acting as a preventive tool for others in proximity to the user, by isolating the carrier immediately. The kit is priced between `20003000 depending upon the global supply, to increase its affordability for the masses. Under normal circumstances, the ready-to-use kits can be received within 23 days of placing the order at their platform. To initiate an effective screening tool for mass screening, the organisation is also in talks to provide bulk orders for early detection.19

Against COVID-19 drugs and experimental molecule are being prepared. SARS-CoV-2 is a single stranded RNA enveloped virus. The angiotensin-converting enzyme 2 (ACE2) receptor of the host cell binds to the spike (S) protein of the viral structure. The host type 2 transmembrane serine protease, TMPRSS2 facilitates the S protein.20 Once the virus enters the host, it starts synthesizing RNA through its RNA dependent RNA polymerase enzyme, which is then translated to products. Structural proteins facilitate the assembly and release of viral particles.21,22

During viral life cycle, chemotherapy is available of various potential targets. There are many non-structural protein promising drug targets which resembles with other coronaviruses (SARS-CoV and MERS-CoV) such as 3-chymotrypsin like protease, papain like protease and RNA-dependent RNA polymerase. Various molecules and their targets are represented in Figure 1.

Figure 1 Mechanism of various drugs/molecules on COVID-19 disease.

Chloroquine and hydroxychloroquine used in prevention and treatment of malaria and chronic inflammatory diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA).23 CQ and HCQ are reliable anti-malarial drugs approved by FDA, which shows positive response against SARS-CoV-2 infections and hence used for the treatment of COVID-19 patients by clinicians.2426 It inhibits the entry of the virus by either altering the configuration of structure of cell receptors or by compete to bind with cellular receptors.27 The glycosylation of ACE-2 cellular receptors can amend by CQ/HCQ which is needed for entry of SARS-CoV-2. Apart from that CQ/HCQ can also prevent the attachment of SARS-CoV-2 to the host cells by decrease the synthesis of sialic acid.

The binding affinity of these drugs is better as compared to the S protein of SARS-CoV-2. Therefore it prevents attachment and entry of virus because of competitive binding of sialic acid and gangliosides present on surface pf target cell.28

In addition to the antiviral activity of CQ/HCQ, they have anti-inflammatory activity that may contribute to its efficacy in treating COVID-19 patients. Through the attenuation of cytokine production, these drugs also have immunomodulatory effects and inhibition of lysosomal and autophagy activity in host cells.24,29 In vitro activity of HCQ with lower EC50 for SARS-CoV-2 as compared to CQ after the growth of 24 hours (HCQ: EC50=6.14 M and CQ: EC50=23.90 M).30

A study from China reported which results in improved radiologic findings, enhanced viral clearance, and reduced disease progression by treating successfully with CQ on 100 COVID-19 cases.31 When treatment given to 6 patients, then it is observed that as compared to HCQ monotherapy (8/14, 57%) the combination of azithromycin with HCQ (6/6, 100%) results in numerically superior viral clearance.32

Other than these positive results, this study has many limitations like intolerance of medication, different viral loads between HQC combination and monotherapy and no safety outcomes are reported.

Another study of 30 patients in China shows there was no difference in virologic outcomes to HCQ plus standard of care (supportive care, interferon, and other antivirals). At 7th day virologic clearance was similar with clearance for the HCQ plus standard of care group and standard care group ie 86.7% vs 93.3% respectively, (P>.05).33 Currently, for COVID-19 treatment several RCTs of both CQ and HCQ examining their roles. To treat COVID 19 500 mg dose of CQ orally once or twice daily is advised.8,9

However, there is shortage of data regarding the optical dose to ensure efficiency of CQ For HCQ, daily dose of 400 mg taken orally is recommended.34

Both the agents are well tolerated by patients with SLE and malaria as demonstrated by their experiences and they can cause rare and serious adverse effect (>10%) such as hypoglycemia, neuropsychiatric effects, and retinopathy.

Lopinavir/ritonavir is FDA approved for treating HIV and it shows in vitro activity against coronavirus by inhibiting 3-chymotrypsin like protease.35 The therapy during early peak viral replication phase (initial 710 days) is important because delayed medication with lopinavir/ritonavir had no effective outcomes.36,37

Although many RCTs of lopinavir/ritonavir examine their role, limited role for lopinavir/ritonavir in COVID-19 treatment is suggested through current data.38

Recent RCT shows that approximately 50% of patients experienced an adverse effect under the lopinavir/ritonavir therapy and 14% of patients stop therapy due to adverse effects on gastrointestinal region. In several COVID-19 investigational trials, alanine transaminase elevations are exclusion criterion. Hepatotoxicity induced by lopinavir/ritonavir could limit patients ability to access these drugs.39

The activity of darunavir is demonstrated in vitro cell models against SARS-CoV-2. With these drugs there is no clinical data is available in COVID 19, but in China RCT of darunavir/cobicistat is going on.40,41 Ribavirin is a analogue to guanine which inhibits viral RNA-dependent RNA polymerase and used as best candidate for treatment of COVID 19.

However, it has limited in vitro activity against SARS-CoV and high doses is required to prevent viral replication (e.g., 1.2 g to 2.4 g orally every 8 hours) and combination therapy. For nCoV treatment no evidence exists for inhaled ribavirin..42 Generally ribavirin is used in combination with interferons in the treatment of MERS, no visible effect is shown on clinical outcomes. A lack of clinical data with ribavirin for treatment of COVID 19, means its therapeutic role must be extrapolated from other nCoV data.43,44 The high doses used during trials SARS resulted in hematologic toxicity and hemolytic anemia in more than 60% of patients. Similar safety concerns were seen in MERS trial, with 40% of patients taking ribavirin with interferon requiring blood transfusions. 75% of patients experienced transaminase elevations while taking ribavirin for SARS. Ribavirin is a teratogen and prescribed as not to be used pregnancy.45,46

It is a nucleoside reverse - transcriptase inhibitor that is worthy in clinical trial against COVID-19. It acts as an inhibitor of RNA-dependent RNA polymerase (RdRp)47 and in SARS-CoV and MERS-CoV infections its pharmacokinetics and characteristics have been studied.48 It inhibits the viral genomic replication and production by disturbed reading due to alteration in the function of viral exonuclease.49

Therefore it can suggested for COVID 19 patients to prevent severity of disease progression such patients are taken to phase 3 trials to check the therapeutic efficiency of remdesivir.50

Favipiravir (T705) is considered as RdRp inhibitor as it is an analog to guanine nucleotide (a derivative of pyrazine carboxamide).51 Initially it was used against influenza but because of its large spectrum antiviral properties, it attracted more attention for treatment of COVID 19.52

An in silico study showed that as compared to lopinavir, atazanavir bound more strongly to the active site of SARS-CoV-2 MPro and an in vitro study found that replication of SARS-CoV-2 inhibited by atazanavir.53

Oseltamivir is used for treatment of influenza because it acts as a neuraminidase inhibitor. It has no data against SARS-CoV-2. Initially in China during the COVID-19 outbreak until the discovery of SARS-CoV-2 as the cause of COVID-19 a large proportion of patients were treated with oseltamivir therapy because outbreak occurred in influenza season.

Once influenza has been excluded this agent has no role in the management of COVID-19.54 Umifenovir has a unique mechanism of action targeting the S protein interaction and inhibiting membrane fusion of the viral envelope. This agent is approved for treatment of influenza in Russia and China and treatment of COVID 19 patients started on the basis of in vitro data which shows its activity against SARS.

A study shows that 67 patients treated with Umifenovir for 9 days had a lower mortality rate and higher discharge rate compared with the patients who were not treated with this medication. This data cannot proof the efficiency of umifenovir, but for evaluating this agent further RCTs are going on in China.55.

For SARS-CoV-2 interferon- and - have been studied, due to their demonstrating activity against MERS by interferon-. Some interferons are listed as an alternative for combination therapy by Chinese guidelines. Traditionally other agents are used to demonstrate in vitro activity to inhibit SARS-CoV-2, but not limited to baricitinib, dasatinib, and cyclosporine. However it should be seen whether it provide protection for COVID 19 patients or not.56

Nitazoxanide has in vitro antiviral activity against MERS and SARS-CoV-2. It is used traditionally as an antihelminthic agent. More studies are required to check the antiviral activity and immunomodulatory effects of this agent. For treatment option for SARS-CoV-2 nitazoxanide is recommended.57 In Japan camostat mesylate is used for treatment of pancreatitis, it prevents cell entry through the host serine protease, TMPRSS2. For future research this mechanism provides an additional drug target.58

The ACE2 receptor is used by SARS-CoV-2 for entry into the host cell. This discovery has increased questions about whether ACE inhibitors and/or angiotensin receptor blockers may efficiently treat COVID-19 or either worsen disease. There are some conflicts if these provide protective effect to COVID-19 patients. Further research is pending for recommending therapy for patients already taking one of these agents.59,60

One of the main challenges in this pandemic is to develop multiple technology platforms for evaluation of agents/molecules against SARS-CoV-2 as this virus shows similarity with various other (Figure 1) corona viruses and shares similar binding receptors (ACE2) in humans (host).61 SARS-CoV-2 has ss-RNA genome of approximately 30 Kbp size and exhibits approximately 89% nucleotide similarly to SARS-CoV found in Chinese bats.20

For SARS-CoV 2 various technologies are being developed such as nucleic acid, replicating viral vector and non-replicating viral vector. New methods based on nucleic acid can facilitate rapid production because they do not need to be fermented. Experiments are conducted to ensure vaccination of larger population without any reduction in efficacy but also with improved immune response along with low dosages.62,63

As of January 2021, more than 200 vaccine candidates for COVID-19 are being tested. Among these almost 52 vaccines are approved for human trials and many other vaccines are in phases I/II and will soon enter phase III trials. Certain national regulatory authorities have nine authorized COVID-19 vaccines.

It represents a classic strategy for viral vaccinations. Finally, a codon deoptimization technology to attenuate the viruses is employed by Codagenix64 and is testing to develop vaccine against SARS-CoV-2, CodaVax-COVID. The inherent immunogenicity and ability to stimulate toll-like receptors (TLRs) is a major advantage of whole virus vaccines. This is especially an issue for coronavirus vaccines, given the findings of increased infectivity following immunization with live or killed whole virus SARS coronavirus vaccines.65

Subunit vaccines depend on producing immune response against S protein to inhibit its binding with host ACE2 receptor.65 Immunogenic virus-like nanoparticles produced by Novavax are based on recombinant expression of the S-protein66 while subunit vaccine consisted of a trimerized SARS-CoV-2 S-protein is developed by Clover Biopharmaceuticals by using their patented Trimer-Tag technology.67

For development of COVID-19 vaccines several major biotech industries have advanced nucleic acid vaccine platforms. Some modifications and formulation have improved nucleic acid performance in humans. This approach may lead to the first licensed nucleic acid based vaccine for humans.

Developing vaccine against the SARS-CoV-2 can cause distinct challenges. Various proteins of SARS-CoV-2 are used for developing proteins like S protein, N protein, M protein is the initial challenge. Developing a vaccine is a long process, starting from product development to the completion of phase III and clinical trials before marketing which takes several years.

Vaccine against COVID-19, known as CoroFlu is under process and its development and testing is done by Bharat Biotech in collaboration with international virologists and vaccine makers. One-drop COVID-19 nasal vaccine named CoroFlu, it is well tolerated in human trials during phase I and phase II. On the backbone of FluGens flu vaccine, CoroFlu has built a candidate known as M2SR. M2SR induces an immune response against the flu; it is a self-limiting version of the influenza virus. To induce immunity against the coronavirus in new virus, Kawaokas lab is trying to insert the gene sequences from SARS-CoV-2 into M2SR.68

To develop a vaccine for SARS-CoV-2, Zydus Cadila, an innovation-driven global pharmaceutical company, initiated a research program along with multiple teams. By reverse genetics the recombinant measles virus (rMV) is produced. It would express codon optimised proteins of the SARS-CoV-2 and provide long-term neutralising antibodies for protection from infection. The plasmid DNA vaccine, also has wide ranging capabilities in developing and manufacturing different vaccines for unmet needs. This is under supervision of the groups Vaccine Technology Centre in India.69

To develop a lead vaccine candidate for SARS-CoV-2 the Vaccine manufacturer Indian Immunologicals Ltd (IIL) has a research collaboration agreement with Australias Griffith University. As part of the cross-continental collaboration, using the latest codon de-optimisation technology Live Attenuated SARS-CoV-2 vaccine could be developed by scientists from IIL and the Griffith University. with a single dose administration this vaccine is expected to provide long protection with an anticipated safety profile for active immunization.70

Now the SII (Serum Institute of india) is preparing its mass production against the coronavirus, mixing out doses of the Covishield candidate vaccine which is being developed by the University of Oxford and the international biopharma company AstraZeneca. In India stage III clinical trials of Covishield are continuing. In the US, Brazil and South Africa the candidate vaccine is also being tested in various stages. Two million doses of the vaccine candidate has already produced over for use in testing by the SII. Recently SII announced a deal with Codagenix, US-based Biotech Company to help develop a vaccine candidate and it is expected that its trials starts by the end of 2020. Nasal COVID-19 vaccine candidate developed by Codagenix Inc. Dubbed the DX-005, manufacturing by SII has started.

After completing preclinical animal studies the coronavirus vaccine entered phase I clinical trials in the United Kingdom by the end of 2020. Bharat Biotech, a private firm collaborated with Indian Council of Medical Research (ICMR) is developing Covaxin. Covaxin has shown good efficacy is said by task force scientist Dr. Rajni Kant ICMR-COVID-19. Bharat Biotech is approved by The Drugs Controller General of India (DCGI) to perform Phase III clinical trials of Covaxin with certain conditions.

Russias president Vladimir Putin endorsed approval of SPUTNIK V (COVID-19 vaccine) that has not passed rigorous medical tests and could have numerous consequences. The effectiveness of the vaccine in response to providing active acquired immunity against COVID-19 and its possible adverse effects remain unknown. Therefore, the fear of vaccination in this particular case may be justified. However, endorsement of a potentially harmful vaccine will inevitably fuel public fears of other existing and future, properly developed, controlled and safe vaccines. Current level of public acceptability of immunization is already worrying, putting at serious risk the effectiveness of any future anti-SARS-CoV-2 vaccination programs, as it has been pointed out by Cornwall 2 and the French COCONEL Group 3. Independently from each other these groups provide evidence that it is a transatlantic phenomenon. Regardless of the suggested correlations between vaccination hesitancy and specific socioeconomic factors, it is clear that anti-vaccination movements are increasingly influential.71 Moreover, the problem is internationally valid, and the rise in the number of adults openly hesitant about routine childhood vaccination in many Western countries justifies the concern about public participation once the COVID-19 vaccine is available.72

In terms of collective immunity, vaccination effectiveness is based on its mass implementation; this may seriously undermine the efforts to protect societies against COVID-19 in the near future. High levels of COVID-19 vaccine hesitancy are reported even from countries severely affected by the pandemic. Only 49% of American respondents plan to vaccinate when the vaccine becomes available.73

Polish research confirms the strong COVID-19 vaccination hesitancy and its international character which is not directly related to the level of confidence in vaccination safety in general. Results of this Polish study show that 28% of adults would not vaccinate against SARS-CoV-2 if the vaccine became available. Alarmingly, a majority (51%) of the reluctant respondents indicated that their minds would not be changed if given information regarding vaccine safety or efficacy, or if threatened with heavy fines. Significantly fewer respondents (37%) supported COVID-19 vaccinations specifically than supported childhood vaccinations in Poland in general (78% in 2018).74 The vaccine hesitancy for the anticipated COVID-19 vaccine varied from very low (26% China) to very high (43%, Czechia, and 44%, Turkey). Surprisingly, the level of unwillingness to vaccinate against COVID-19 is in most countries much higher than regular vaccination reluctance, which varies between 3% (Egypt) and 55% (Russia). Such high levels of vaccination hesitancy may be detrimental to public health. According to current estimates, the benefits of herd immunity are achievable if 67% of the population is vaccinated.75,76

The most effective vaccination programs in the past effectively eradicated certain deadly diseases, such as smallpox which was achieved by combining the mandatory preventive vaccination programs with coordinated education efforts.77 Coronaviruses mortality rate is the highest among elders and people with comorbidities or conditions that affect their immune system. Some occupations have been identified as being the riskiest in terms of contracting COVID-19 such as health-care workers (dental hygienists, family practitioners, and nurses), transportation personnel (flying attendants, and school bus drivers), kindergarten, school teachers, fire fighters and restaurant personnel.78 Highest risk of death and highest risk of contraction should constitute the main criteria for mandatory vaccination. Mandatory vaccination will definitely trigger massive opposition especially bearing in mind the massive protests against social distancing measures and face masks. Focusing at the beginning only on some groups with transparent justification may help weaken the opposition to it.79

The high share of the population unwilling to vaccinate along with the number of people who are unable to receive the COVID-19 vaccine due to certain medical reasons suggests herd immunity may be out of reach. Information about the high death tolls and hospital overflows from the COVID-19 pandemic has recently flooded onto online media, but has apparently not convinced much of the worlds population to plan to be vaccinated. If the disturbing images being streamed live on social media cannot convince a fair share of the population to protect themselves from lethal risk, then educational or social campaigns may be limited in their effect. Educational efforts would be further undermined by the lack of trust in public authority figures, which fuels conspiracy theories and validates medical fake news. In this focused review we have discussed the challenges and opportunities faced during the management of COVID-19 in India.

Health-care systems across developed and developing nations are under tremendous pressure. The majority of this responsibility is being shouldered by frontline health-care workers to limit the spread of the novel coronavirus. They put their lives on the line in order to do so. Here we highlight some challenges faced by frontline HCW and propose certain recommendations to reduce the burden.

The exposure to the virus causes severe illness and mortality to a significant extent and also leads to physical and psychological exhaustion. This pandemic leads to health departments calling retired and experienced medical staff and clinical scientist back to work. Deficient supplies of personal protective equipment (PPEs) and other vital necessities is reported in various news channels all over the world. Majorly WHCs are affected and they are working in the emergency, they need PPEs and other vital necessities most.

In this pandemic, battling endless hours, staff shortages and deficient supplies, most are isolated from their families, affecting them physically, mentally, and emotionally, which will increase the morbidity and ill health.80 These mental health problems will not only affect decision making ability, judgement and attention of HCWs, but also affect the understanding the disease and have a long-lasting impact on their overall well-being.80

A few recommendations are proposed which are listed from all the information received around this issue.

Health-care staff/HCWs are also the most important resource as hospitals, equipments and PPEs in this pandemic situation. Post Traumatic Stress Disorder is reported in many health-care workers who have no time to protect themselves as well as their families. If any staff gets infected then they should be quarantined themselves, which leads to a shortage of staff and then healthy workers are stretched further for endless duties with lack of sleep and anxiety. For frontline health workers testing kits must be prioritized, as well as for weak communities (senior citizens) more susceptible to the virus and those who have many pre-existing diseases.81,82

Health-care workers face a high risk of getting infected as they take care of patients who are already infected. Protective clothing, sufficient hand sanitizers, washing paraphernalia and head covers are essential commodities which have to be provided to them in sufficient amount. Along with providing PPEs in adequate amount, its disposal methodology is also an important step across all the clinical areas since it can be one of the reasons of spreading infection.31

These are key phrases which provide the adequate time for the systems to gather resources and capacity to help in breaking the chain of transmission. The virus infects exponentially which is very clear and many will contract it very soon. State should provide premises to serve as isolation ward and quarantine spaces. All hospitals should use their full area to create control committees to monitor activities to ensure protocols are implemented for effective control. The loop has to be complete, involving community systems, governments and primary health-care workers are key, since not everyone will report to hospitals, if community transmission will be rampant.

The comfort and willingness in working for a health system which has an effective plan, magnifies many times in a pandemic. Protocols in local languages for better understanding and awareness material based on science research have been useful. Offering free transport service between work and home, childcare support and meal vouchers can reduce domestic stress and allow single-minded effort towards the health service.83

Apart from the various negative effect imposed by the pandemic, positive vibes of it cannot be neglected. The pandemic situation significantly improves air quality in different cities across the country, reduces GHGs emission, lessens water pollution and noise, and reduces the pressure on the tourist destinations, which may assist with the restoration of the ecological systems.84 These changes may be short term but are important for maintenance of environmental balance. Apart from this, various successful models like that of Dharavi and Kerala model were implemented which restricted the cases to a minimum through observing the spread in the localities, studying the prototype of spread, and strict use of methods to control the disease in Kerala. Dharavi restricted the coronavirus cases with a strategy of attack not defence and elucidated triumphant results in 2 months.85

There are more than 56 COVID-19 candidate vaccines in clinical evaluation of which 13 are in phase III trials and another 166 candidate vaccines are in preclinical evaluation (Table 1). All top candidate vaccines will be delivered through intra-muscular injection and are designed for a two-dose schedule.86 More recently our group has suggested the combinatorial use of childhood vaccines (BCG, MMR and OPV) along with the COVID-19 dedicated vaccines could be a potential strategy to control the COVID-19 pandemic worldwide.87

Table 1 Prospective Therapeutic Representative Against COVID-19 Disease

Strain B.1.1.7 was first detected in the United States in December 2020 followed by B.1.351, in South Africa P.1, in Brazil and Japan, B.1.427 and B.1.429. These two variants were first identified in California in February 2021. COVID-19 variant from India is B.1.617; one of the lineages is B.1.617.2, which has been detected most frequently in the US and the U.K.88 Recently the black fungus is now maiming COVID-19 patients in India. Mucormycosis is an invasive infection caused by a class of molds called mucormycetes. It has an overall mortality rate of 50%, and may be being triggered by the use of unhygienic oxygen cylinders and steroids, a life-saving treatment for severe and critically ill COVID-19 patients.89

In this review, we have been discussed the stories related to prevention strategies, chemotherapeutics and vaccines strategies to manage COVID-19. Apart from that we have discussed the challenges faced by HCWs and their prevention. Combating COVID-19 is still a challenge also due to the poorly-based counsel for using an experimental amalgamation of antimalarials and antimicrobials as treatment; the use of steroids; and antihypertensive drugs during the course of the disease. Interruption of the transmission of SARS-CoV-2 through engineered vaccines is top in the priority followed by the intense research to find out the potential treatment to control this viral infection.

All authors contributed to data analysis, drafting or revising the article, have agreed on the journal to which the article will be submitted, gave final approval of the version to be published, and agree to be accountable for all aspects of the work.

There is no funding to report.

Divakar Sharma and Dileep Tiwari were associated with Hericure Healthcare Pvt Ltd. Currently, Divakar Sharma is working in Maulana Azad Medical College at the time of this review. The authors reported no other potential conflicts of interest for this work.

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2. Fischer F, Raiber L, Boscher C, et al. COVID-19 and the elderly: who cares? Front Public Health. 2020;8:151. doi:10.3389/fpubh.2020.00151

3. Vahia IV, Blazer DG, Smith GS, et al. COVID-19, mental health and aging: a need for new knowledge to bridge science and service. Am J Geriatr Psychiatry. 2020;28(7):695. doi:10.1016/j.jagp.2020.03.007

4. COVID-19. Tracker India; 2020. Available from: https://www.COVID19india.org/. Accessed April 15, 2020.

5. Census-India. 2011. Available from: https://censusindia.gov.in/2011-Common/CensusData2011.html. Accessed April 15, 2020.

6. Mishra VK. Indias projected aged population (65?), projected life expectancy at birth and insecurities faced by aged population. Ageing International. 2020;45:7284.

7. De Witt Huberts J, Greenland K, Schmidt W-P, et al. Exploring the potential of antimicrobial hand hygiene products in reducing the infectious burden in low-income countries: an integrative review. Am J Infect Control. 2016;44(7):764771. doi:10.1016/j.ajic.2016.01.045

8. U.S. Food and Drug Administration. Temporary policy for preparation of certain alcoholbased hand sanitizer products during the public health emergency (COVID-19). Guidance for Industry; March, 2020. Available from: https://www.fda.gov/media/136289/download. Accessed July 21, 2021.

9. Edwards J, Patel G, Wareham DW. Low concentrations of commercial alcohol hand rubs facilitate growth of and secretion of extracellular proteins by multidrug-resistant strains of Acinetobacter baumannii. J Med Microbiol. 2007;56(12):15951599. doi:10.1099/jmm.0.47442-0

10. healthcare-in-europe.com [Internet]. Will resistant bacteria be the end of alcohol hand sanitizers? 2018. Available from: https://healthcare-in-europe.com/en/news/will-resistant-bacteria-be-the-end-of-alcohol-hand-sanitizers.html#. Accessed July 21, 2021.

11. Lan J, Song Z, Miao X, et al. Skin damage among health care workers managing coronavirus disease-2019. J Am Acad Dermatol. 2020;82(5):12151216. doi:10.1016/j.jaad.2020.03.014

12. The Government of India issues simple guidelines, for controlling spread of COVID-19 in densely populated areas. Available from: https://pib.gov.in/PressReleseDetailm.aspx?PRID=1614064. Accessed July 21, 2021.

13. TIFAC explores best methods to revive Indian economy post COVID-19.Available from: https://dst.gov.in/tifac-explores-best-methods-revive-indian-economy-post-COVID-19. Accessed July 21, 2021.

14. TDB approves support for indigenous company for ramping up production of COVID-19 diagnostic kits.Available from: https://dst.gov.in/tdb-approves-support-indigenous-company-ramping-production-COVID-19-diagnostic-kits. Accessed July 21, 2021.

15. NBRI scientists develop herbal hand-sanitiser.Available from: https://vigyanprasar.gov.in/isw/NBRI-scientists-develop-herbal-hand-sanitiser.html. Accessed July 21, 2021.

16. Indian researchers to go for clinical trial of sepsis drug against novel coronavirus.Available from: https://vigyanprasar.gov.in/wp-content/uploads/Indian-researchers-to-go-for-clinical-trial-of-sepsis-drug-against-novel-coronavirus-21apr20.pdf. Accessed July 21, 2021.

17. Advisory_on_Cepheid_Xpert_Xpress_SARS_CoV2_testing.Available from: https://icmr.nic.in/sites/default/files/upload_documents/Advisory_on_Cepheid_Xpert_Xpress_SARS_CoV2_testing.pdf. Accessed July 21, 2021.

18. AMU alumnus develops COVID-19 testing kit, approved by ICMR. Available from: https://www.amu.ac.in/about3.jsp?did=2495. Accessed July 21, 2021.

19. Bione launches rapid COVID-19 at-home screening test kit after ICMR approval.Available from: https://zeenews.india.com/india/bione-launches-rapid-COVID-19-at-home-screening-test-kit-after-icmr-approval-2273752.html. Accessed July 21, 2021.

20. Wu F, Zhao S, Yu B, et al. Complete genome characterisation of a novel coronavirus associated with severe human respiratory disease in Wuhan, China. bioRxiv. 2020;2020:919183. doi:10.1101/2020.01.24.919183

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Challenges and Successes of Dealing with COVID-19 in India | RRTM - Dove Medical Press

Nanotechnology Market Share, Industry Size, Leading Companies Outlook, Upcoming Challenges and Opportunities till 2028 – The Market Writeuo – The…

The Latest research study released by DBMR Global Nanotechnology Market with 350+ pages of analysis on business Strategy taken up by key and emerging industry players and delivers know how of the current market development, landscape, technologies, drivers, opportunities, market viewpoint and status. Understanding the segments helps in identifying the importance of different factors that aid the market growth. The report shows market share, size, trends, growth, trends, applications, competition analysis, development patterns, and the correlations between the market dynamics and forecasts for 2020 to 2027 time-frames. The report aims to provide an overview of global Nanotechnology Market with detailed market segmentation by product/application and geography. The report provides key statistics on the Market status of the players and offers key trends and opportunities in the market. Research report has been compiled by studying the market in-depth along with drivers, opportunities, restraints & other strategies as well as new-developments that can help a reader to understand the exact situation of the market along with the factors that can limit or hamper the market growth and the report also has been updated with Impacts & effects of Coronavirus pandemic and how it has influenced consumer behavior& the growth of the market as well as industries.

The Global Nanotechnology Market is expected to reach USD 24.56 billion by 2025, from USD 7.24 billion in 2017 growing at a CAGR of 16.5% during the forecast period of 2020 to 2025

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Nanoscience is the study of extremely small things. The development of nanotechnology is being growing in many fields, as it has various applications, such as in chemistry, biology, physics, materials science and engineering. Nanotechnology deals with the use of nanoparticle of size of 1 to 100 nm to be used in all major field of medical. Materials designed from nanotechnology are lighter, stronger and more durable. In oncology research, nanotechnology assists in cancer eradication. Nanotechnology based device are also used in fitness monitoring. Smartphone apps and bracelets are developed based on nanotechnology concept. A nano based device is used to sense the body temperature, heartbeat and others which are sent back to the reader. After analysing the temperature and heartbeat, medical staff monitors the condition. All these nano based devices helps to drive the market. For elder people, battery-free printed graphene sensors are also developed which helps in gathering the health condition of the elder population, enables remote healthcare and improves the quality of life. In diagnostic and prevention, nanotechnology plays a vital role in cancer diagnostics. Nanotechnology based devices can detects the biomarker produced by the circulating tumor cells (CTCs) on the onset of cancer. Based on nanotechnology, two main methods of circulating tumor cells (CTC) isolations are magnetic and microfluidic methods. In clinical development fluorescent nano sensors are used for in-vivo monitoring of biomarkers. Another application of nanotechnology is nanomedicine which has potential application in diagnosis and therapy medicine for regeneration of tissues and organs.

This Nanotechnology Market 2020 Reportencompasses an infinite knowledge and information on what the markets definition, classifications, applications, and engagements are and also explains the drivers and restraints of the market which is obtained from SWOT analysis. By applying market intelligence for this Nanotechnology Market report, industry expert measure strategic options, summarize successful action plans and support companies with critical bottom-line decisions. Additionally, the data, facts and figures collected to generate this market report are obtained forms the trustworthy sources such as websites, journals, mergers, newspapers and other authentic sources. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed. This report also states import/export consumption, supply and demand Figures, price, cost, revenue and gross margins.

According to this reportGlobal Nanotechnology Marketwill rise from Covid-19 crisis at moderate growth rate during 2020 to 2027. Nanotechnology Market includes comprehensive information derived from depth study on Nanotechnology Industry historical and forecast market data. Global Nanotechnology Market Size To Expand moderately as the new developments in Nanotechnology and Impact of COVID19 over the forecast period 2020 to 2027.

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Nanotechnology Market report provides depth analysis of the market impact and new opportunities created by theCOVID19/CORONAVirus pandemic. Report covers Nanotechnology Market report is helpful for strategists, marketers and senior management, And Key Players in Nanotechnology Industry.

List of Companies Profiled in the Nanotechnology Market Report are:

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Nanotechnology Reportdisplays data on key players, majorcollaborations, merger & acquisitions along with trending innovation and business policies. The report highlights current and future market trends and carries out analysis of the effect of buyers, substitutes, new entrants, competitors, and suppliers on the market. The key topics that have been explained in this Nanotechnology market report include market definition, market segmentation, key developments, competitive analysis and research methodology. To accomplish maximum return on investment (ROI), its very essential to be acquainted with market parameters such as brand awareness, market landscape, possible future issues, industry trends and customer behavior where this Nanotechnology report comes into play.

The Segments and Sub-Section of Nanotechnology Market are shown below:

By Type (Nano composites, Nano materials, Nano tools, Nano devices, Others)

By Applications (Healthcare, Environment, Energy, Food & Agriculture, Information & Technology, Others)

By Industry (Electronics, Cosmetics, Pharmaceutical, Biotechnology, Others

Market Size Segmentation by Region & Countries (Customizable):

Key questions answered

What impact does COVID-19 have made on Global Nanotechnology Market Growth & Sizing?

Who are the Leading key players and what are their Key Business plans in the Global Nanotechnology market?

What are the key concerns of the five forces analysis of the Global Nanotechnology market?

What are different prospects and threats faced by the dealers in the Global Nanotechnology market?

What are the strengths and weaknesses of the key vendors?

Market Segmentation: Global Nanotechnology Market

The global nanotechnology market is segmented based on product type, application, industry and geographical segments.

By Product Type (Nano Composites, Nano Materials, Nano Tools, Nano Devices, Others), By Applications (Healthcare, Environment, Energy, Food & Agriculture, Information & Technology, Others), By Industry (Electronics, Cosmetics, Pharmaceutical, Biotechnology, Others), By Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa)

Based on product type , the market is segmented into nano-composites and nano materials, nano tools, nano devices, and others. Nano-composites are further sub segmented into nanoparticles, nanotubes and nano clays. Nano materials are further sub-segmented into nano fibers, nano ceramic products and nano magnetics. Nano tools are further sub-segmented into nanolithography tools and scanning probe microscopes. Nanodevices are further sub-segmented into nanosensors and nanoelectronics.

On the basis of application, the market is further segmented into healthcare, environment, energy, food & agriculture, information & technology and others.

Based on industries, the market is segmented into electronics, cosmetics, pharmaceutical, biotechnology and others.

Based on geography, the market report covers data points for 28 countries across multiple geographies namely North America & South America, Europe, Asia-Pacific and, Middle East & Africa. Some of the major countries covered in this report are U.S., Canada, Germany, France, U.K., Netherlands, Switzerland, Turkey, Russia, China, India, South Korea, Japan, Australia, Singapore, Saudi Arabia, South Africa and, Brazil among others.

Strategic Points Covered in Table of Content of Global Nanotechnology Market:

Chapter 1: Introduction, market driving force product Objective of Study and Research Scope the Nanotechnology market

Chapter 2: Exclusive Summary the basic information of the Nanotechnology Market.

Chapter 3: Displaying the Market Dynamics- Drivers, Trends and Challenges of the Nanotechnology

Chapter 4: Presenting the Nanotechnology Market Factor Analysis Porters Five Forces, Supply/Value Chain, PESTEL analysis, Market Entropy, Patent/Trademark Analysis.

Chapter 5: Displaying market size by Type, End User and Region 2010-2019

Chapter 6: Evaluating the leading manufacturers of the Nanotechnology market which consists of its Competitive Landscape, Peer Group Analysis, BCG Matrix & Company Profile

Chapter 7: To evaluate the market by segments, by countries and by manufacturers with revenue share and sales by key countries (2020-2027).

Chapter 8 & 9: Displaying the Appendix, Methodology and Data Source

Finally, Nanotechnology Market is a valuable source of guidance for individuals and companies in decision framework.

Thanks for reading this article; you can also get individual chapter wise section or region wise report version like North America, Europe or Asia.

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A copper-infused COVID-19 mask is making its way out of a WVU lab – Times-West Virginian

MORGANTOWN Whether behind the hotel front desk or the restaurant counter, hospitality and customer service employees come face-to-face with guests from all walks of life for hours on end.

With the delta variant on the rise and an upswing in COVID-19 cases, the hospitality business faces the challenge of staffing positions as people weigh their personal safety against their employment as the pandemic rages on.

Masking up remains one safe precaution.

But its also an uncomfortable gesture, as some masks may inflict wear and tear on the face or not provide an adequate level of protection for the worker, explained Ajay Aluri, founding director of the Hospitality Innovation and Technology Lab at West Virginia University.

As a native of India, where copper is king and touted for its antimicrobial properties, Aluri thought, Why not make a safer, more comfortable mask infused with copper when using for a longer period of time?

Copper has a special place in the culture and tradition of India, said Aluri, also associate professor of hospitality and tourism management in the Chambers College of Business and Economics. People wear copper bracelets and use copper utensils for cooking. And theres a notion, from the COVID standpoint, that copper is antimicrobial.

From the HIT Lab was born Hygenmask, a three-layered facemask containing a copper-infused nano-coated fabric, a sustainable bamboo fabric and an ePTFE (a biomaterial) filter. Wearers also dont have to worry about elf ears since the masks lack ear loops. Elastic head loops go over the head and can be tightened for a customized fit.

WVU HIT Lab is a platform for both industry and academia to come together to solve the problems of the hospitality and tourism industry. Before Hygenmask, Aluri and his students created Hygenkey, a copper touch tool with antiviral and antibacterial qualities, in response to the pandemic in 2020.

The mask is ideally for people who are always at the front desk or talking to people six to eight hours at a time, whether in restaurants, resorts, airports, or any hospitality and tourism industry, Aluri said. Some of these masks out there, if you wear them for a long time, it can be really rough on your skin. So we strived to make it more hygienic and sustainable from a fabric standpoint.

One of Aluris partners recommended a sustainable bamboo fabric, which offers a smooth feel but still fits tight around the face, he said.

But you dont have to take his word for it. Aluri reached across campus to ask scientists with the WVU School of Medicines Center for Inhalation Toxicology (iTOX) to test the product. Since the onset of the pandemic, the Center has been at the forefront of testing all sorts of masks from N95 alternatives to WVU gaiters to the Singers Mask to double masks.

The Center found that Aluris mask blocked up to 93% of droplets being respired.

The Hygenmask offers good protection to its users, said Timothy R. Nurkiewicz, director of the Center and E.J. Van Liere Endowed Professor and chair of the Department of Physiology and Pharmacology. Combined with physical distancing, good HVAC, limiting time in a crowd and limiting the crowd size, the mask should afford the users some confidence.

Researchers conducted fit testing, which evaluates how well a mask protects the person wearing the mask. A score of 100 is necessary to pass a N95 mask. Gaiters and saggy disposable masks typically score a one.

Aluris mask ranged from six-to -15 on the study participants.

Those numbers are substantially better than what you would find with your average cloth masks, which usually gets a fit factor of two, said Karen Woodfork, a teaching associate professor in the Department of Physiology and Pharmacology who was part of the research team.

People send us all kinds of masks and most of them get ones or twos, Nurkiewicz said. When we saw Ajays mask scoring in that range, that tells you theres a bit of protection there.

Nurkiewiczs lab did not test the copper properties of the mask.

Perhaps theres no better way to test a product than actually using it.

Aluri donned the mask during a 14-hour flight to India.

Im only taking it down when Im eating or drinking, Aluri said. I had no marks on my face and Hygenmask was quite comfortable.

Most of all, Nurkiewicz and his team believe that Aluris mask accomplishes its purpose and will be of benefit to its target audience those who serve the public day-to-day.

The mask sits away from your mouth enough so you can articulate better, Nurkiewicz said. Also, in terms of regular breathing, you will labor more with a mask that sits right on your lips. Theres some space there, making it more comfortable and making the wearer more likely to keep it on for a longer period of time.

We are making critical coverage of the coronavirus available for free. Please consider subscribing so we can continue to bring you the latest news and information on this developing story.

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A copper-infused COVID-19 mask is making its way out of a WVU lab - Times-West Virginian

Using digital twins in health care to stave off the grim reaper – VentureBeat

The Transform Technology Summits start October 13th with Low-Code/No Code: Enabling Enterprise Agility. Register now!

VentureBeat caught up with NTT Research Medical & Health Informatics Lab director Dr. Joe Alexander, who elaborated on his view of the future of bio digital twins, which promise to improve precision medicine and bring digital transformation to the health care industry.

Japanese telecom giant NTT has launched a major initiative to improve digital health through precision medicine using digital twin technology. This project is part of NTT Research, a new R&D hub focused on basic research. The goal is to address long-term technological challenges with solutions that, once achieved, can positively impact wider ranges of businesses and many parts of our lives. These projects are not tied to specific product roll-out plans but could lead to much more significant long-term improvements than conventional incremental research conducted by enterprises.

VentureBeat: What exactly is medical and health informatics where does it fit into the landscape of other enterprise medical software like EHRs, diagnostics, telemedicine, and research?

The acquisition, storage, retrieval, and use of health care information to foster better collaboration among a patients various health care providers is the study of health informatics. It plays a critical role in the push toward health care reform. Health informatics is an evolving specialization that links information technology, communications, and health care to improve the quality and safety of patient care. EHRs help providers better manage care for patients and are an important part of health informatics.

Telemedicine has more to do with the access and sharing of medical information for the purpose of treating patients remotely. The term diagnostics can be applied to any process or device that involves techniques for (medical) diagnoses.

One current area of research that is of particular interest to our team is precision cardiology. This includes the cardiovascular bio digital twin as well as heart-on-a-chip technologies.

Research at MEI Labs does not currently target EHR software development or telemedicine per se. Our work does support remote monitoring, diagnostics, and advanced therapeutics.

VentureBeat: What is the bio digital twin initiative, and how do you plan to advance it?

Alexander: A bio digital twin is an up-to-date virtual representation (an electronic replica) which provides real-time insights into the status of a real-world asset to enable better management and to inform decision-making. This concept has been applied to the preventive maintenance of jet engines and may be applied as well to the predictive maintenance of health.

The Bio Digital Twin (BioDT) initiative aims to individualize and revolutionize health care by use of BioDT technologies. We will first realize precision cardiology on multiple scales through development of a cardiovascular BioDT (CV BioDT) and heart-on-a-chip platforms. The CV BioDT is at the whole organ physiological system level, whereas the heart-on-a-chip is at a microfluidics level, making use of an individuals stem cells to make in vitro organs.

For the CV BioDT, we will begin with acute conditions (acute myocardial infarction and acute heart failure) and progress to chronic cardiovascular conditions and their co-morbidities and complications. The latter requires heavy dependence on organ systems other than the heart. Ultimately, based on our accumulating knowledge of underlying physiological and pathophysiological mechanisms (together with advanced sensing technologies), we will be able to move into wellness and prevention.

VentureBeat: What is the value of a digital twin, and how does it build upon other technologies for capturing and managing medical data or simulating things?

Alexander: We expect that our bio digital twin will best enable individualized care. By reproducing an individuals entire physiology based on causal mechanisms, we should be able to predict health issues as well as provide recommendations for therapies in complex patients through what if scenario testing.

Autonomous therapies delivered by the bio digital twin become possible, where the physician would simply monitor autonomous devices. Virtual clinical trials in populations of bio digital twins also become feasible and would dramatically accelerate drug (or vaccine) development.

What we are proposing is not evolutionary, but revolutionary. An ambitious project of this scope and scale will take time. We will certainly need continuously to inventory the evolving trajectories of clinical and technology landscapes for facilitatory impact points.

VentureBeat: Why did you decide to start with the heart, and how will this complement other, similar efforts?

Alexander: We started with cardiovascular disease because it is the global leading cause of death. One of the principal missions of NTT Research is to provide long-term benefits to humanity; this is fundamental to deciding what projects to pursue.

Our immediate cardiovascular disease targets will be acute myocardial infarction (AMI) and acute heart failure (acute HF). We will pursue chronic heart failure and other conditions afterwards.

VentureBeat: Whats next in digital twins and why?

Alexander: Following development of the CV BioDT, our next pursuit will be neurodegenerative diseases, e.g., Alzheimers disease and Parkinsons disease. Our reasoning here is similar: neurodegenerative diseases are the 2nd leading cause of death, at least in the U.S.

VentureBeat: What kinds of things are you working on with nano and microscale sensors and electrodes?

Alexander: MEI Lab is developing organ-on-a-chip microfluidics platforms as well as three-dimensionally transformable and implantable electrodes. This work involves the exploration and examination of new materials that include nanofibers and nanofiber-based paper electrodes.

VentureBeat: Which ones show the most promise in the short term and possibility in the long term?

Alexander: This is a difficult question for me to answer since I am not directly involved in the research. However, all our targets tend to be long term. Based on current progress, microscale three-dimensionally transformable electrodes for sensing are more promising in the shorter term, followed by similar types of electrodes for both stimulating and sensing. Organ-on-a-chip platforms will likely mature in the longer term.

VentureBeat: What are some of the key developments in digital biomarkers, wearable technologies, and remote sensing you are exploring?

Alexander: While we are in an ongoing background process of doing a clinical and technical landscape inventory of such devices, we have not yet developed a strategy within the MEI Lab to point us in any particular directions. Our focus right now is on acute conditions where patients are hospitalized and well-instrumented for access to the directly observable data necessary for early model building, verification, and validation.

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Using digital twins in health care to stave off the grim reaper - VentureBeat

3d Cell Culture Market: How Leading Companies Respond to New Market Drivers by Thermo Fisher Scientific, Nanofiber Solutions, Advanced Biomatrix,…

Detailed research added by Adroit Market Research offering a comprehensive analysis of the developments, growth outlook, driving factors, and key players of the 3d Cell Culture market in the latest research report. The research study concisely dissects the 3d Cell Culture and unearths valuable estimations pertaining to the profit projections; market size, sales capacity, and numerous other crucial parameters. Also, the 3d Cell Culture Market report appraises the industry fragments as well as the driving factors impacting the remuneration scale of this industry.

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Competition landscape

-Business Strategies of Leading and prominent market players in 3d Cell Culture.

-Product offering and development analysis.

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Competitive Landscape Thermo Fisher Scientific, Nanofiber Solutions, Advanced Biomatrix, Dickinson and Company

The 3d Cell Culture Market has been segregated into various crucial divisions including applications, types, and regions. Each market segment is intensively studied in the report contemplating its market acceptance, worthiness, demand, and growth prospects. The segmentation analysis will help the client to customize their marketing approach to have a better command of each segment and to identify the most prospective customer base.

Market Analysis by Applications:By Application,(Regenerative medicine,Drug discovery,Stem cell research,Cancer research)

Market Analysis by Type:By End-User, (Academic institutes,Contract research laboratories,Pharmaceutical & biotechnology companies), By Product Type, (Services,Microchips,Bioreactors,Gels,Scaffold-based platforms,Scaffold-free platforms,Solid scaffolds,Nano-porous scaffolds,Micro-porous scaffolds,Macro-porous scaffolds)

1. Which end-user is likely to play a crucial role in the development of the 3d Cell Culture market?

2. Which regional market is expected to dominate the 3d Cell Culture market in 2020?

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4. Why are market players eyeing opportunities in region 1?

5. What are the growth prospects of the 3d Cell Culture market in region 1 and region 2?

6. What impact does COVID-19 have made on 3d Cell Culture Market Growth & Sizing?

(1) The information presented in the report helps your decision-makers to become prudent and make the best business choices.

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6. Impact Analysis of COVID-19 on 3d Cell Culture Market

To conclude, the 3d Cell Culture Market report will provide the clients with a high-yielding market analysis assisting them to understand the market status and come up with new market avenues to capture hold of the market share.

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Chapter 1 Market Overview

Chapter 2 Industry Chain

Chapter 3 Environmental Analysis

Chapter 4 Market Segmentation by Type

Chapter 5 Market Segmentation by Application

Chapter 6 Market Segmentation by Region

Chapter 7 Market Competitive

Chapter 8 Major Vendors

Chapter 9 Conclusion

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3d Cell Culture Market: How Leading Companies Respond to New Market Drivers by Thermo Fisher Scientific, Nanofiber Solutions, Advanced Biomatrix,...

Complementary Protection May Be at Hand With a COVID-19-Preventing Nasal Spray – Newsweek

Vaccinated citizens can still transmit the COVID-19 virus and its variants to other people. Salvacion USA Inc. is therefore excited to introduce the development of a complementary product, designed for adults 18 and older, it hopes could accompany COVID-19 vaccines to offer additional protection: a nasal spray to shield the nasal passages and prevent further viral transmission. (However, CDC guidelines should still be followed, and those who are eligible should receive the COVID-19 vaccination.)

COVID-19 vaccination numbers in the U.S. have now reached nearly 50 percent, and Americans are eager to resume life post-pandemic. However, as flu season approaches and the COVID-19 vaccines' efficacy and longevity have come under question, communities are increasingly concerned about the virus and its Delta and unknown variantsespecially as children return to school this fall. Experts have also speculated this pandemic could become endemic, cycling from season to season. For these reasons, we must continue to stay ahead of the rapidly updating situation and arrive at innovative strategies.

Salvacion's new technology is gaining momentum among the scientific community. The National Cancer Instituteestablished Nanotechnology Characterization Laboratory (NCL) recently selected Salvacion USA Inc. as one of its Assay Cascade awardees for Salvacion's nasal spray, trade name: COVIXYL-V. The announcement appeared in NCL's June 2021 quarterly newsletter, in which Salvacion noted, "COVIXYL-V is intended to reduce SARS-CoV-2 in nasal passages, a main point of entry for the virus in humans. Our unique virus-blocking product, optimized in collaboration with NCL, contains agents which block the virus from attaching to tissue and reducing the viral load in the tissue milieu."

According to NCL's announcement, "Nanomedicines accepted into the program will undergo a rigorous evaluation that may include sterility and endotoxin testing, physicochemical characterization, in vitro hemato- and immunotoxicity, and in vivo studies to evaluate safety, efficacy and pharmacokinetics. The studies are tailored to each individual nanomedicine and are designed to promote the clinical translation of these novel therapies."

Among Nanotechnology Characterization Laboratory's's five awardees, Salvacion is the only one working on a product intended to avert the spread of COVID-19. As an Assay Cascade awardee, NCL commits to funding Salvacion studies free of charge.

Ryan Hwang, a Salvacion spokesman, said, "Our product is preventative and protects nasal passages, halting transmission. Vaccines are developed to protect against COVID-19, but they are not designed to stop transmission. Our strategy is complementary to the effectiveness of vaccines by deterring COVID-19 infection by blocking the transmission."

Salvacion's clinical human trials are currently underway. In vitro and in vivo testing performed thus far suggested that the nasal spray inhibited 99.99 percent of COVID-19. This spray effectively blocked COVID-19 activity in the nasal passages of hamsters, the prime entry points for the virus. One study, performed by an independent BSL-3 laboratory (which, according to Public Health Emergency, is a lab "used to study infectious agents or toxins that may be transmitted through the air and cause potentially lethal infections"), showed that COVID-19 was 99.99 percent inactivated post-spray, with no clinical symptoms experienced by Syrian hamsters from the treatment. No adverse reactions were reported in the hamsters following administration. The data developed in this study showed that the nasal spray product was effective in neutralizing the virus within low concentrations. An additional barrier effect animal study undertaken at an independent laboratory also assessed the COVID-19 blocking effects of the nasal spray. It concluded that the spray created a physical barrier to block the viral particles from taking hold on the surface of the nasal passages. The testing was to prove the mechanism of the nasal spray is capable of blocking the transmission of COVID-19 by creating a physical barrier. The next step is the conducting of a human clinical trial, which is now underway. Salvacion is currently seeking an Emergency Use Authorization (EAU) for its COVIXYL-V nasal spray from the FDA.

This nasal spray is made of ingredients listed as GRAS, or "Generally Recognized As Safe," by the FDA. Unlike other products based on isopropyl alcohol currently being tested, it appears Salvacion's nasal spray could offer a unique blocking system with enhanced effectiveness at a very low concentration. A worldwide patent has been filed for this technology.

"Our nasal spray product may well be the key to moving back to a world that some have thought lost forever to the 'new normalcy,'" said Abdul Gaffar, a Salvacion chemist and recipient of the American Chemistry Society's Heroes of Chemistry Award, who invented this nasal spray.

The contents of this article are for informational purposes only and do not constitute medical advice. It's important to consult with your medical providers and the CDC before making any medical decisions or changes to your health plan, particularly with regard to COVID-19 and its variants.

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Complementary Protection May Be at Hand With a COVID-19-Preventing Nasal Spray - Newsweek

McMaster University researchers awarded more than $3M in Federal funds for projects – insauga.com

Eleven researchers working out of Hamilton's McMaster University have been awarded almost $3.3 million from the Federal Government for projects deemed to be "on the cutting edge of science andinnovation."

On Wednesday (Aug. 11), Francois-Philippe Champagne, Minister of Innovation, Science and Industry, announced that more than $77 million had been earmarked to support 332 research infrastructure projects at 50 universities acrossCanada.

The funding, made possible through the Canada Foundation for Innovation's (CFI) John R. Evans Leaders Fund (JELF), is expected to help universities attract and retain topresearchers.

"From developing sustainable building materials to creating new laboratories based on Indigenous principles and community engagement, these awards support essential and urgent research," said CFI president and CEO Roseann O'Reilly Runte, in a pressrelease.

"With the necessary spaces and tools, Canada's researchers will play a meaningful role on the global stage and contribute significantly to the quality of life today and for generations tocome."

The more than $3 million going to Mac researchers will help advance their work in health, materials and electrificationresearch.

Projects at Mac that will benefit from the fundinginclude:

Faculty ofEngineering

Bilgen Berker, Electrical and Computer Engineering Project: An Acoustic Noise and Vibration Measurement Facility for Low-noise and High-efficiency Electric Motor DrivesAward:$200,000

Ryan Lewis, Engineering Physics Project: Advanced Epitaxial Nanostructures and Materials LaboratoryAward:$190,584

Zahra Keshavarz-Motamed, Mechanical Engineering Project: Developments of Diagnostic and Predictive Tools and Regulatory Device Testing Machines for Cardiovascular DiseasesAward:$185,000

Maureen Lagos Paredes, Materials Science & Engineering Project: Momentum-resolved EELS Spectroscopy of Beam-sensitive Nanoscale MaterialsAward:$387,788

Faculty of HealthSciences

Lisa Carlesso, Rehabilitation Science Project: Understanding Pain Mechanisms and Management in Neuromusculoskeletal RehabilitationAward:$129,000

Michael McGillion, Nursing Project: Improving Perioperative and canceR Outcomes Through Excellence and appliCation of Virtual Technologies (PROTECT) LabAward:$800,000

Ishac Nazy, Medicine Project: Investigating Novel Mechanisms in Immune-mediated Platelet DisordersAward:$160,000

Michael Surette, Medicine Project: Metagemomics and Genomics of the Microbiome, Infectious Disease and Host ResponseAward:$650,000

Faculty ofScience

Katherine Bujold, Chemistry & Chemical Biology Project: Establishment of Nucleic Acid Nanomedicine Laboratory at McMaster UniversityAward:$75,005

Katrina Choe, Psychology, Neuroscience & Behaviour Project: Neural Mechanisms Linking Autism-risk Genes with Impaired Social BehaviorAward:$400,000

Jeremy Walsh, Kinesiology Project: Integrative Psychophysiology Research LabAward:$100,000

A full list of research projects and funding recipients benefitting from this investment can be found on the CFI website.

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McMaster University researchers awarded more than $3M in Federal funds for projects - insauga.com

A sportsbook is coming to Cardinals’ stadium, as NFL team announces partnership with BetMGM – Yahoo Sports

There will be a sportsbook in an NFL stadium for the start of the 2022 season. For anyone who knows the history of the NFL and sports betting, that's a dizzying step that nobody would have ever imagined just a few years ago.

The Arizona Cardinals announced a partnership with BetMGM and Gila River Hotels & Casinos for retail and online sports betting.

The most interesting part of the announcement was that BetMGM "plans to open retail sportsbooks at the three Arizona Gila River properties and at State Farm Stadium, home of the Cardinals."

The plan is for the sportsbook to open inside State Farm Stadium for the 2022 season. That's the first time an NFL team has announced plans for a sportsbook in the stadium.

"This is a tremendous opportunity to build upon our long-standing relationship with Gila River and launch a new one with BetMGM," Arizona Cardinals owner Michael Bidwill said in a release. "They are best-in-class partners whose excellence and expertise in this emerging space will provide a new and innovative way to engage and interact with our fans."

English soccer fans won't be shocked by this news, because they're accustomed to betting at the stadium, but it's a new step for the NFL. Before the U.S. Supreme Court allowed states to decide whether to legalize sports betting, the NFL fought betting at every turn. The NFL was slow to embrace betting even as many states adopted new laws to make it legal. Now the league has done a complete turn and is fully embracing it.

The latest step is a sportsbook at the Cardinals' stadium. It likely won't be the last NFL stadium to have one.

There are plans for a sportsbook at the Arizona Cardinals' stadium for the start of the 2022 season. (Photo by Kevin Abele/Icon Sportswire via Getty Images)

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A sportsbook is coming to Cardinals' stadium, as NFL team announces partnership with BetMGM - Yahoo Sports