James Webb Space Telescope Launch Is Making Astronomers Very Anxious – The New York Times

What do astronomers eat for breakfast on the day that their $10 billion telescope launches into space? Their fingernails.

You work for years and it all goes up in a puff of smoke, said Marcia Rieke of the University of Arizona.

Dr. Rieke admits her fingers will be crossed on the morning of Dec. 24 when she tunes in for the launch of the James Webb Space Telescope. For 20 years, she has been working to design and build an ultrasensitive infrared camera that will live aboard the spacecraft. The Webb is the vaunted bigger and more powerful successor to the Hubble Space Telescope. Astronomers expect that it will pierce a dark curtain of ignorance and supposition about the early days of the universe, and allow them to snoop on nearby exoplanets.

After $10 billion and years of delays, the telescope is finally scheduled to lift off from a European launch site in French Guiana on its way to a point a million miles on the other side of the moon. (Late on Tuesday, NASA delayed the launch at least two days).

An informal and totally unscientific survey of randomly chosen astronomers revealed a community sitting on the edges of their seats feeling nervous, proud and grateful for the team that has developed, built and tested the new telescope over the last quarter-century.

I will almost certainly watch the launch and be terrified the entire time, said Chanda Prescod-Weinstein, a professor of physics and gender studies at the University of New Hampshire.

And there is plenty to be anxious about. The Ariane 5 rocket that is carrying the spacecraft has seldom failed to deliver its payloads to orbit. But even if it survives the launch, the telescope will have a long way to go.

Over the following month it will have to execute a series of maneuvers with 344 single points of failure in order to unfurl its big golden mirror and deploy five thin layers of a giant plastic sunscreen that will keep the telescope and its instruments in the cold and dark. Engineers and astronomers call this interval six months of high anxiety because there is no prospect of any human or robotic intervention or rescue should something go wrong.

But if all those steps succeed, what astronomers see through that telescope could change everything. They hope to spot the first stars and galaxies emerging from the primordial fog when the universe was only 100 million years or so old, in short the first steps out of the big bang toward the cozy light show we inhabit today.

The entire astronomy community, given the broad range of anticipated science returns and discovery potential, has skin in the game with the telescope, said Priyamvada Natarajan, an astrophysicist at Yale. We are all intellectually and emotionally invested.

But the telescope has been snake bitten during its long development with cost overruns and expensive accidents that have added to the normal apprehension of rocket launches.

Michael Turner, a cosmologist at the Kavli Foundation in Los Angeles and past president of the American Physical Society, described the combination of excitement and terror, he expected to feel during the launch.

The next decade of astronomy and astrophysics is predicated on J.W. being successful, Dr. Turner said, referring to the James Webb Space Telescope, and U.S. prestige and leadership in space and science are also on the line. That is a heavy burden to carry, but we know how to do great things.

That opinion was echoed by Martin Rees of Cambridge University and the Astronomer Royal for the British royal households.

Any failure of JWST would be disastrous for NASA, he wrote in an email. But if the failure involves a mechanical procedure unfurling a blind, or unfolding the pieces of the mirror this will be a mega-catastrophic and embarrassing P.R. disaster. Thats because it would involve a failure of something seemingly simple that everyone can understand.

Dr. Natarajan, who will use the Webb to search for the origins of supermassive black holes, said, I am trying to be Zen and not imagine disastrous outcomes.

But in describing the stakes, she compared the telescope to other milestones of human history.

Remarkable enduring achievements of human hand and mind, be it the temples of Mahabalipuram, the pyramids of Giza, the Great Wall or the Sistine Chapel have all taken time and expense, she said. I truly see JWST as one such monument of our times.

Alan Dressler of the Carnegie Observatories in Pasadena, who was chair of a committee 25 years ago that led to the Webb project, responded with his own question when asked how nervous he was.

When you know someone is about to have critical surgery, would you sit around and have a conversation about what if it fails? he wrote. He added that his colleagues know there is no certainty here, and it does no good for any of us to ruminate about it.

Another astronomer who has been involved with this project from the beginning, Garth Illingworth of the University of California, Santa Cruz, said in an email that he was optimistic about the launch despite his reputation of being a glass is half empty kind of guy.

The deployments are complex but my view is that all that is humanly possible has been done! he wrote. He said that even if there were surprises in the telescopes deployment, he did not expect these to be either major or mission terminating not at all.

Other respondents to my survey also took refuge from their nervousness in the skill and dedication of their colleagues.

Andrea Ghez of the University of California, Los Angeles, who won the Nobel Prize in 2020 for her observations of the black hole in the center of our galaxy, said she kept herself sane by trusting that really smart people have worked really hard to get things right.

That thought was seconded by Tod Lauer, an astronomer at NOIRLab in Tucson, Ariz., who was in the thick of it when the Hubble Space Telescope was launched and found to have a misshapen mirror, which required repair visits by astronauts on the now-retired space shuttles. He said his feelings regarding the upcoming launch were all about the engineers and technicians who built the Webb telescope.

You very quickly respect the team nature of doing anything in space, and your dependence on scientists and engineers that you may never even know to get it all right, he said. Nobody wants it to fail, and I have yet to meet anyone in this who didnt take their part seriously.

He added that astronomers had to trust their colleagues in rocket and spacecraft engineering to get it right.

Someone who knows how to fly a $10 billion spacecraft on a precision trajectory is not going to be impressed by an astronomer, who never took an engineering course in his life, cowering behind his laptop watching the launch, Dr. Lauer said. You feel admiration and empathy for those people, and try to act worthy of the incredible gift that they are bringing to world.

And if anything does go wrong, some astronomers said they would keep in perspective that its only hardware, not people, at stake.

Should anything bad happen, I will be heartbroken, Dr. Prescod-Weinstein said. I am glad that at least human lives arent on the line.

There was also a lot to look forward to if everything works as intended, said Dr. Rieke, who worked on the telescopes infrared imaging device.

When the camera turns on well have another party, she said.

Read more here:

James Webb Space Telescope Launch Is Making Astronomers Very Anxious - The New York Times

Why the worlds astronomers are very, very anxious right now – Kathimerini English Edition

What do astronomers eat for breakfast on the day that their $10 billion telescope launches into space? Their fingernails.You work for years, and it all goes up in a puff of smoke, said Marcia Rieke of the University of Arizona.

Rieke admits her fingers will be crossed on the morning of Dec. 24 when she tunes in for the launch of the James Webb Space Telescope. For 20 years, she has been working to design and build an ultrasensitive infrared camera that will live aboard the spacecraft. The Webb is the vaunted bigger and more powerful successor to the Hubble Space Telescope. Astronomers expect that it will pierce a dark curtain of ignorance and supposition about the early days of the universe and allow them to snoop on nearby exoplanets.

After $10 billion and years of delays, the telescope is finally scheduled to lift off from a European launch site in French Guiana on its way to a point 1 million miles on the other side of the moon.

An informal and totally unscientific survey of randomly chosen astronomers revealed a community sitting on the edges of their seats feeling nervous, proud and grateful for the team that has developed, built and tested the new telescope over the last quarter-century.

I will almost certainly watch the launch and be terrified the entire time, said Chanda Prescod-Weinstein, a professor of physics and gender studies at the University of New Hampshire.

And there is plenty to be anxious about. The Ariane 5 rocket that is carrying the spacecraft has seldom failed to deliver its payloads to orbit. But even if it survives the launch, the telescope will have a long way to go.

Over the following month it will have to execute a series of maneuvers with 344 single points of failure in order to unfurl its big golden mirror and deploy five thin layers of a giant plastic sunscreen that will keep the telescope and its instruments in the cold and dark. Engineers and astronomers call this interval six months of high anxiety because there is no prospect of any human or robotic intervention or rescue should something go wrong.

But if all those steps succeed, what astronomers see through that telescope could change everything. They hope to spot the first stars and galaxies emerging from the primordial fog when the universe was only 100 million years or so old in short, the first steps out of the big bang toward the cozy light show we inhabit today.

The entire astronomy community, given the broad range of anticipated science returns and discovery potential, has skin in the game with the telescope, said Priyamvada Natarajan, an astrophysicist at Yale. We are all intellectually and emotionally invested.

But the telescope has been snake bitten during its long development with cost overruns and expensive accidents that have added to the normal apprehension of rocket launches.

Michael Turner, a cosmologist at the Kavli Foundation in Los Angeles and past president of the American Physical Society, described the combination of excitement and terror he expected to feel during the launch.

The next decade of astronomy and astrophysics is predicated on J.W. being successful, Turner said, referring to the James Webb Space Telescope, and U.S. prestige and leadership in space and science are also on the line. That is a heavy burden to carry, but we know how to do great things.

That opinion was echoed by Martin Rees of Cambridge University and the Astronomer Royal for the British royal households.

Any failure of JWST would be disastrous for NASA, he wrote in an email. But if the failure involves a mechanical procedure unfurling a blind, or unfolding the pieces of the mirror this will be a mega-catastrophic and embarrassing P.R. disaster. Thats because it would involve a failure of something seemingly simple that everyone can understand.

Natarajan, who will use the Webb to search for the origins of supermassive black holes, said, I am trying to be Zen and not imagine disastrous outcomes.

But in describing the stakes, she compared the telescope to other milestones of human history.

Remarkable enduring achievements of human hand and mind, be it the temples of Mahabalipuram, the pyramids of Giza, the Great Wall or the Sistine Chapel have all taken time and expense, she said. I truly see JWST as one such monument of our times.

Alan Dressler of the Carnegie Observatories in Pasadena, who was chair of a committee 25 years ago that led to the Webb project, responded with his own question when asked how nervous he was.

When you know someone is about to have critical surgery, would you sit around and have a conversation about what if it fails? he wrote. He added that his colleagues know there is no certainty here, and it does no good for any of us to ruminate about it.

Another astronomer who has been involved with this project from the beginning, Garth Illingworth of the University of California, Santa Cruz, said in an email that he was optimistic about the launch despite his reputation of being a glass is half empty kind of guy.

The deployments are complex but my view is that all that is humanly possible has been done! he wrote. He said that even if there were surprises in the telescopes deployment, he did not expect these to be either major or mission terminating not at all.

Other respondents to my survey also took refuge from their nervousness in the skill and dedication of their colleagues.

Andrea Ghez of the University of California, Los Angeles, who won the Nobel Prize in 2020 for her observations of the black hole in the center of our galaxy, said she kept herself sane by trusting that really smart people have worked really hard to get things right.

That thought was seconded by Tod Lauer, an astronomer at NOIRLab in Tucson, Arizona, who was in the thick of it when the Hubble Space Telescope was launched and found to have a misshapen mirror, which required repair visits by astronauts on the now-retired space shuttles. He said his feelings regarding the upcoming launch were all about the engineers and technicians who built the Webb telescope.

You very quickly respect the team nature of doing anything in space, and your dependence on scientists and engineers that you may never even know to get it all right, he said. Nobody wants it to fail, and I have yet to meet anyone in this who didnt take their part seriously.

He added that astronomers had to trust their colleagues in rocket and spacecraft engineering to get it right.

Someone who knows how to fly a $10 billion spacecraft on a precision trajectory is not going to be impressed by an astronomer, who never took an engineering course in his life, cowering behind his laptop watching the launch, Lauer said. You feel admiration and empathy for those people, and try to act worthy of the incredible gift that they are bringing to world.

And if anything does go wrong, some astronomers said they would keep in perspective that its only hardware, not people, at stake.

Should anything bad happen, I will be heartbroken, Prescod-Weinstein said. I am glad that at least human lives arent on the line.

There was also a lot to look forward to if everything works as intended, said Rieke, who worked on the telescopes infrared imaging device.

When the camera turns on well have another party, she said. [Science Times; Out There]

This article originally appeared in The New York Times.

Go here to see the original:

Why the worlds astronomers are very, very anxious right now - Kathimerini English Edition

Astronomy: Just as in the Bible story of the three wise men, there is today still much to ponder in the night sky – The Columbus Dispatch

Kenneth Hicks| Special to The Columbus Dispatch USA TODAY NETWORK

In the world of astronomy, all eyes are on the launch of the James Webb space telescope.If successful, the James Webbwillbringus into a new realm ofknowledge, much like the Hubble space telescope did back in 1990.

At the time of writing, that launchhasyet to happen.So,Ill turn to a different topic.

Soon, Christmas will have come and gone.Children will have looked up in the sky and wondered whether they couldsee Santas sleigh. But the night sky appears much different to children in the city and those in the country.

If youve ever seen the night sky out in the country, away from bright city lights, its a scene that you wont forget.In the city, you willsee only a few of the brightest stars, due to the glare of the city lights. In the country, you can see thousands of stars on a pitch-black sky. Itsa sight to behold.

Atthe time of the birth of Jesus, there were no city lights and the stars held a special place in the hearts and minds of people livingthen.There was no understanding of science, so those who studied stars werereallydoing astrology, which is, of course, very different from astronomy.

Many people believe that the three wise men, as described in the Bible,were astrologers. Theystudied the movements of the planets (called wandering stars back then, since the planets change position relative to the fixedbackgroundof the stars) and other changes to the night sky.

The Bethlehem star could have been a supernova oranother event, like the merging of two neutron stars, and the astrologers of the time would interpret this as heralding a momentous occasion.

Today, wenowknow that the night sky holds the secrets to many thingsthatwe scientists are still too ignorant to understand.It is humbling to think that we have the technology to send a telescope into space that will look back to the beginning of time, yet we still dont understand the nature of dark matter or the ephemeral dark energy.

Together,dark matter and dark energy make up about 95% of the mass of the universe.

If you couldhibernateand wake up 1,000 years from now, you would probably find that our current understanding of the universe is reallyveryprimitive.Just like the three wise men, who could not have foreseen our current knowledge of astronomy, it is hard to predict the future explanation of dark matter and dark energy.

But the key to future progress is bright young people who have a natural curiosity of what goes on in the night sky.

Kenneth Hicks is a professor of physics and astronomy at Ohio University in Athens.

hicks@ohio.edu

Read more here:

Astronomy: Just as in the Bible story of the three wise men, there is today still much to ponder in the night sky - The Columbus Dispatch

How astronomers decided where to point NASA’s James Webb Space Telescope – The Verge

In late March, Grant Tremblay was sitting at his computer at his home in Cambridge, Massachusetts, listening in on a Zoom meeting, when he saw a string of emails pop up in his inbox. The title of each email read: Cycle 1 JWST Notification Letter.

He knew immediately that this was the day he and his colleagues in the astronomy community had been eagerly awaiting: it was Blacker Friday.

Blacker Friday, to be clear, didnt have anything to do with discounts, or Fridays. (It was a Tuesday.) It was the day that Tremblay, an astrophysicist at the Harvard and Smithsonian Center for Astrophysics, and other astronomers around the world, would learn if they would receive a small amount of time to use the James Webb Space Telescope, or JWST, one of the most powerful space telescopes ever created.

Blacker Friday is named after Brett Blacker, who co-runs the science policies group at the Space Telescope Science Institute, or STScI. Each year, the institute is responsible for selecting which astronomers will get time to use NASAs Hubble Space Telescope. And each year, after a lengthy decision-making process, Blacker would send out a flurry of emails to hopeful astronomers, all on the same day at the same time, informing them if their proposals to use the telescope had been accepted or rejected. Thus, Blacker Friday also sometimes known as the Blacker Apocalypse was born.

This year the stakes were even higher on Blacker Friday because, for the first time ever, astronomers were being informed if they would get time with JWST, a brand-new space observatory that is significantly larger and more powerful than Hubble. Set to launch to deep space at the end of December, the nearly $10 billion NASA-built telescope promises the ability to peer into the recesses of the Universe like never before. Ahead of JWSTs launch, STScI had the daunting task of figuring out which of the 1,173 proposals for the observatorys first year of life known as Cycle 1 should get time with the telescope. How do you prioritize what the most advanced piece of space equipment in the world should do when it first turns on?

Well, the science has to be nothing short of revolutionary.

What is deemed most interesting is science that is considered transformational that will change our view of the universe, Klaus Pontoppidan, an astronomer and JWST project scientist at STScI, tells The Verge. We dont want the observatory to do things a little better than what has been done before. We wanted to answer fundamental questions that cannot be answered any other way.

NASA plans to launch JWST the day before Christmas. But for the astronomy community, the launch is the real holiday. JWST is one of the most anticipated space science missions of the 21st century, as it has the ability to reshape astronomy and astrophysics as we know it.

Thats because the telescope is the closest thing we have to a time machine. Sporting a 21-foot-wide gold-plated mirror, JWST will be able to see in the infrared with incredible sensitivity. Itll be able to see objects that are 10 to 100 times fainter than what the Hubble Space Telescope can see, and itll be capable of seeing things in 10 times better detail. It will gather light from stars and galaxies located up to 13.6 billion light-years away light that has taken 13.6 billion years to reach the telescopes mirrors. Since the Universe is thought to be roughly 13.8 billion years old, the galaxies that JWST will be observing likely formed just 100 to 250 million years after the Big Bang. Our Universe was in its infancy then, and JWST will be providing us with the baby photos.

In addition to peering back in time, the telescope will help us understand the large-scale structure of the Universe, and perhaps tell us if it will go on expanding forever. It will peer into the centers of galaxies, finding supermassive black holes and helping astronomers learn how these enigmatic objects have evolved over time. It will observe the births and deaths of stars. It will even look back at our own Solar System to study the faintest objects at the edge of our cosmic neighborhood. And it will be able to look at the edges of worlds orbiting around distant stars. Nearly every area of astronomy that you can think of will be addressed, Christine Chen, an associate astronomer at STScI, tells The Verge.

The promise of JWST has always been just over the horizon. Since an iteration of the telescope was first conceived in 1989, the road to the launchpad has been paved with cost overruns and technical issues. Naively, NASA originally envisioned a launch between 2007 and 2011, for a total cost between $1 billion and $3.5 billion. But JWST continued to miss one target launch date after next, while its total cost ballooned to $9.7 billion.

As everyone waited for JWST to materialize, the world of astronomy blossomed. An entirely new field has emerged since the 1990s, one that revolves around the study of planets outside our Solar System, or exoplanets. Since the first detection of an exoplanet was confirmed in 1992, weve discovered thousands of these far-off worlds orbiting alien stars. In 2017, astronomers shocked the world when they announced the discovery of an entire alien solar system, consisting of seven planets roughly the size of Earth all orbiting around a dwarf star. And three of the seven planets, known as the TRAPPIST-1 system, sit in the stars habitable zone, where temperatures are thought to be just right so that water can pool on a planets surface.

After discovering such a bounty of exoplanets, astronomers are now eager to find what is referred to as Earth 2.0: a planet thats the size of our world, orbiting a star like our Sun at the right distance for liquid water to form. But exoplanets are incredibly faint, and traditional methods for detecting them like watching stars dim ever so slightly as planets pass in front of them cant tell us what might be lurking on their surfaces. JWST, however, is powerful enough that it may be able to detect light passing directly through the atmospheres of some alien worlds and use that light to say what kinds of chemicals are present in the atmosphere. Perhaps, it could even detect signs of life.

Its a capability no one really envisioned when JWST was first being designed, but now its considered one of the more exciting areas of science that the telescope will touch upon. It also means there are even more people who are very eager to get just a few hours with the most advanced space telescope ever built.

All of our transformational leaps in observational astronomy are enabled by making ever larger pieces of glass, right? says Tremblay. And when you make a damn piece of glass thats large enough and especially when you launch it into space the discovery space for that observatory grows with time. It doesnt diminish.

While JWST is ultimately a NASA mission, its the Space Telescope Science Institutes job to determine what JWST actually does in space. You can think of us as sort of the software part of the observatory, Pontoppidan says, whereas NASA is the hardware part.

However, STScI had to wait a long time before figuring out the schedule for JWSTs first year, and there were a few false starts along the way. When it seemed like the telescope would be ready to launch in 2019, the Institute called on astronomers to submit their proposals by March 2018. Then just a week before the deadline, NASA announced that the telescope wouldnt launch until 2020 at the earliest. STScI abruptly postponed the deadline until a more concrete launch date was determined.

Another postponement came again in March 2020, due to the onset of the COVID-19 pandemic. Finally, after what seemed like an eternity, astronomers turned in their proposals by November 24th, 2020, two days before Thanksgiving. Then it was time for STScI to sift through the more than 1,000 ideas that had been submitted.

STScI knew that it couldnt handle this process alone. The Institute created a Time Allocation Committee including astronomers and astrophysicists from around the world. They were separated into 18 panels, each one consisting of about 10 people tasked with looking over proposals for different areas of space science and ranking them based on three important criteria: how much the proposal will impact knowledge within a subfield, how much it will advance astronomy in general, and whether the proposed idea requires the unique capabilities of JWST to be successful. Given just how many people want to use JWST, the Institute didnt want to allot time to an observation that could be done with any of the other telescopes currently online.

With all of these benchmarks in mind, the committee got to work evaluating all of the proposals. To try to eliminate as much bias as possible from the selection process, the process was dual anonymous. That means that the people writing the proposals had no idea who would be evaluating them, and the people on the committee had no idea whose proposals they were analyzing. As a result, 30 percent of the winning proposals are helmed by women, and scientists studying for their PhDs also saw more success in getting their ideas approved. Now since nobody knows who wrote the proposal, students can be just as successful as their mentors, Chen says.

After painstaking debate, the committee selected the proposals it found to be the most transformative. It then gave each proposal a certain number of hours of observation time. Ultimately, STScI selected a total of 266 proposals, submitted by scientists from 41 countries around the globe.

Tremblay, the Harvard astrophysicist, had submitted nine proposals for JWSTs first year. On Blacker Friday, nine new emails sat in his inbox. (The emails dont come from Blacker anymore but from the Science Mission Office at STScI). He quickly clicked through them and read one after the next:

Dear Dr. Tremblay,

We regret to inform you...

He read the phrase nine times in total.

It was a disappointment but definitely not a shock. I wasnt broken up by not getting time this year, Tremblay tells The Verge. I knew it would be immensely, immensely competitive for Cycle 1, as it should be. And its okay. Well resubmit again.

Nearly 2,000 miles away, Caitlin Casey, an astronomer at the University of Texas, was having a very different kind of Blacker Friday. She was at home in Austin, holding her sleeping two-month-old baby in her lap, while scrolling her phone. Thats when she saw the email pop up in her inbox.

Dear Dr. Casey,

We are pleased to inform you...

The ambitious project she and her team had proposed, called Cosmos Web, had just been approved. And the Institute was giving Casey a whopping 208 hours with JWST to fulfill her project, the most of anyone who had submitted proposals. The project will stare at a particularly large patch of sky the size of three full Moons, an area that spans up to 63 million light years across. Doing so will create a portrait of the young universe similar to the Hubbles iconic Hubble Deep Field, which showcased some of the earliest galaxies we could observe at the time. With JWSTs enhanced capability, the team will be imaging galaxies that are even older at even greater levels of detail. If the Hubble Deep Field were printed on an eight-and-a-half by 11 sheet of paper, Cosmos Web would be like a 16-foot by 16-foot mural on the side of a building, says Casey.

Staying silent so as not to wake her sleeping child, Casey jubilantly logged into Slack and messaged her colleague and co-principal investigator on the project, Jeyhan Kartaltepe, an astrophysicist at the Rochester Institute of Technology.

All I had to say was, We got it, Casey tells The Verge. She was dumbfounded, too. And I think for the rest of that day, both her and I, we could not even [focus]. It was a flurry of excitement and just overwhelmed with that news.

Aside from Cosmos Web, the seven-planet TRAPPIST-1 system will be getting a lot of attention during JWSTs first year, with up to seven different programs dedicated to studying this strange cluster of worlds. JWST will be looking in the atmospheres of these planets, as well as dozens more weve found throughout the Universe, hoping to determine if these places might be suitable for life as we know it. And there are hundreds more targets that JWST will observe, including galaxies, quasars, black holes, and more.

While the committee tried to be as logical as possible with their final decisions, everyone agrees that serendipity does come into play. Probably there were a lot of amazing programs similar to ours that were also up for consideration, says Casey. Theres always a little element of luck in the final selection process. Maybe someone on the panel just liked the specific way we presented some information.

Roughly 10,000 hours of observing time is allotted to different groups for JWSTs first year of life. About 6,000 hours were given to the scientists who submitted proposals around the world, while nearly 4,000 hours were already set aside for scientists who helped design and build JWST and its instruments. The STScI also has about 460 hours of discretionary time which have been allotted for what is known as Early Release Observations. Data from these hours, scheduled to be done in the first five months of science, will become public immediately, so that anyone even those who did not get time with the telescope can analyze the observations and write their own studies.

Anyone who does the math will realize that 10,000 hours is actually more than the number of hours in a calendar year. STScI purposefully overprescribed JWSTs time to account for any snafus. STScI will be scheduling JWSTs observations in two-week increments, during which time the observatory will point at its intended targets autonomously. However, its possible that JWST will fail to execute some commands properly from time to time. If that happens, JWST will simply go on to the next observation. And the Institute wants to make sure the telescope has fallback plans when such errors occur. We dont want to get to the end of the year, and then run out of observations, Pontoppidan says.

STScI is also planning to carve out time for targets we dont know about yet. These are events like the explosive destruction of a star, known as a supernova, or when two particularly dense stars come together in a cataclysmic merger, known as a kilonova. If astronomers spot a particularly juicy supernova occurring in the sky, JWSTs operators are prepared to reorient the schedule so that they can quickly observe the aftermath of the eruptive event.

The prioritization of JWSTs observations will be determined by the time of the year, and where things are positioned in the sky. But as for the very first observation the telescope will do, NASA knows what it is but wont tell. Its supposed to be a surprise.

While flexibility is going to be key for JWST Cycle 1, STScI guarantees that all the proposals that have been approved will occur. Because each target in the sky is in JWSTs view twice a year, if for some reason a target is missed, there is a second opportunity to observe it six months later. If a target isnt observed in the first year, it might simply bleed over into next year. Basically, everything that gets through the committee recommended and approved will execute on the telescope, Chen says, as long as the telescope, you know, works.

If everything goes well with the telescopes launch, NASA plans to conduct at least five and a half years of science with it, and hopefully up to 10 years. Ultimately, the observatorys lifetime is dictated by its limited fuel reserves, which are needed to help reorient JWST in space. Whenever that fuel runs out, JWSTs mission will end.

That finality is still quite a ways off. First, JWST must launch and actually survive its trip through space. Once it reaches its final home 1 million miles from Earth, JWST will undergo six months of commissioning when scientists meticulously test out the instruments on board before the real science begins.

And then, after a period of transformational science has passed, itll be time to submit another round of proposals. Though Tremblay will be involved with one JWST proposal for Cycle 1 as a collaborator rather than the principal investigator, he does plan to submit his ideas again for Cycle 2. And hell understand if it doesnt get accepted.

As an astronomer we get professionally used to rejections; I could wallpaper my hallway with rejections that Ive received, Tremblay says. Its just a reflection of the fact that the community has immense demand for the telescope. And I think its a great thing.

Update December 20th, 1:50PM ET: This article was updated to clarify the principal investigators on Cosmos Web.

See the rest here:

How astronomers decided where to point NASA's James Webb Space Telescope - The Verge

Immersive audio at the world’s largest astronomy museum – AV Magazine

The Shanghai Astronomy Museum, the largest in the world devoted to the celestial sciences, has been equipped with Meyer Sound immersive audio systems in its two main venues.

Designed by Ennead Architects of New York, the 39,000 square metre museum, with its curvilinear exterior devoid of any straight lines or right angles, encloses three main exhibition zones Home, Cosmos, and Odyssey with the free-flowing architecture encompassing three dominant architectural features: Oculus, Inverted Dome, and Sphere.

Occupying the interior of the Sphere is an 8K Dome Theater, which hosts an audience of 250 for a 20-minute all-enveloping spectacle covering 4.6 billion years of cosmic evolution. Designed using Meyer Sounds MAPP 3D system design and prediction tool, the theatres immersive audio system comprises 32 Meyer Sound UPJ-1P loudspeakers that encircle the 20-meter dome in three tiers.

A cluster of four 900-LFC subwoofers delivers low-frequency emphasis, while three-dimensional spatial sound trajectories are created using the Spacemap feature in CueStation. Up to 64 tracks of audio program source are available from the DWTRX recording/playback module of the D-Mitri digital audio platform.

An Optical Planetarium, nestled inside the Home Zone, combines recreations of constellations and planetary movements with a film about nature and the universe. Here the audio system encircles the audience with 36 UPJunior loudspeakers on four levels, again augmented by four 900-LFC subwoofers for low-frequency effects. Loudspeaker optimization is provided by one GALAXY 408 and two GALAXY 816 Network Platforms.

The Shanghai Astronomy Museum is currently the largest museum focused on the astronomical sciences in the world, and we are honoured to be part of the project, says Zhu Sihai, managing director of Shanghai Broad Future Electro Technology which supplied the audio system.

The linear sound reproduction and immersive technologies offered by Meyer Sound help make the experience here unique and breathtaking. We expect to bring this heightened level of experience to more venues around the country.

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Immersive audio at the world's largest astronomy museum - AV Magazine

Hubble captures the site of an epic supernova, spotted by amateur astronomers – Digital Trends

The eyes of the astronomy community are firmly on one event this week: The launch of the James Webb Space Telescope, the brand-new space observatory from NASA, the European Space Agency, and the Canadian Space Agency, which will be the worlds most powerful space telescope and the successor to the Hubble Space Telescope. But that launch doesnt mean that Hubble will be going away, as the older telescope will continue to be used to capture beautiful images of space in the visible light spectrum, while James Webb will focus primarily on capturing data in the infrared wavelength.

This weeks image from the Hubble Space Telescope is an example of the striking visuals it is still possible to capture with this 30-year-old technology. It shows the galaxy NGC 3568, a barred spiral galaxy (like our Milky Way) which is located around 57 million light-years away in the constellation of Centaurus.

One distinct feature of this galaxy is that it was the location of a huge supernova, when a star reached the end of its life and exploded in a dramatic cosmic event. The light from this supernova reached Earth in 2014 and, unusually, was spotted not by professional astronomers but by a team of amateur astronomy enthusiasts who watch for supernovas from their backyards.

While most astronomical discoveries are the work of teams of professional astronomers, this supernova was discovered by amateur astronomers who are part of the Backyard Observatory Supernova Search in New Zealand, the European Space Agency writes. Dedicated amateur astronomers often make intriguing discoveries particularly of fleeting astronomical phenomena such as supernovae and comets.

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Hubble captures the site of an epic supernova, spotted by amateur astronomers - Digital Trends

Workshop on astronomy – The Hindu

Air Force School, Sulur, organised a workshop on astronomy for school students and teachers reently. A release said the workshop included slides and videos to explain the celestial objects. This was followed by a science exhibition and stargazing using telescope.

The Good Shepherd Health Education Centre and Dispensary organised a seminar on empowerment of women here recently. A release said District Social Welfare Officer P. Thangamani inaugurated the event, which was attended by community development experts, academicians and community organisation members from Chennai, Coimbatore, Madurai, Tiruchi and New Delhi.

Minister for Information and Publicity M.P. Saminathan and Minister for Adi Dravidar and Tribal Welfare N. Kayalvizhi Selvaraj on Friday participated in the groundbreaking ceremony for construction works in Tiruppur Corporation under the Namakku Naame scheme. A release said the works to construct a storm water drain and a mini-bridge at Thanthai Periyar Nagar in Ward No. 57 (Zone-IV) at 60 lakh began. The Ministers also accepted petitions from the public following the event, a release said.

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How to explore the universe from our home? – BusinessLine

By far my favourite thing about my job as an astronomer is those rare moments when I get to see beautiful distant galaxies, whose light left them millions to billions of years ago. Its a combination of pure awe and scientific curiosity that excites me about galaxy hunting.

In astronomy today, much of our work is handling enormous amounts of data by writing and running programmes to work with images of the sky. A downside to this is that we dont always have that hands-on experience of looking at every square inch of the universe while we study it.

Im going to show you, though, how I get my fix of wonder by looking at galaxies that only a select few people will ever have seen, until now. In just our observable universe we estimate there are over 2 trillion galaxies!

Only a few decades ago astronomers had to tediously examine photographic plates after a long, cold and lonely night of observing. In the 21st century, we have access to information any time, anywhere via the internet.

Automatic telescopes and surveys now provide us with so much data we require machines to help us analyse it. In some cases, human eyes will only ever look at what the computers have deemed is interesting! Massive amounts of data are hosted online, just waiting to be admired, for free.

Aladin Lite is one of the greatest online tools available to look at our universe through the eyes of many different telescopes. Here we can scan the entire sky for hidden galaxies, and even decipher information about their stellar populations and evolution.

Lets start our universal tour by searching for one of the most visually stunning galaxies out there, the Cartwheel Galaxy. In the Aladin interface, you can search for both the popular name of an object (like cartwheel galaxy) or known co-ordinates. The location will be centred in the interface.

The first image of the Cartwheel Galaxy we see is from optical imaging by the Digitised Sky Survey. The colours we see represent different filters from this telescope. However, these are fairly representative of what the galaxy would look like with our own eyes.

Also read: NASA's James Webb Space Telescope launched on daring quest to behold first stars

A general rule of thumb as an astronomer is that colour differences within galaxies are because of physically different environments. Its important to note that things that look blue (shorter wavelengths) are generally hotter than things that look red (longer wavelengths).

In this galaxy, the outer ring appears to be more blue then the centre red section. This might hint at star formation and stellar activity happening in the outer ring, but less so in the centre.

To confirm our suspicions of star formation we can select to look at data from different surveys, in different wavelengths. When young stars are forming, vast amounts of UV radiation are emitted. By changing the survey to GALEXGR6/AIS, we are now looking at only UV wavelengths, and what a difference that makes! The whole centre section of the galaxy seems to disappear from our image. This suggests that section is likely home to older stars, with less active stellar nurseries.

Aladin is home to 20 different surveys. They provide imaging of the sky from optical, UV, infrared, X and gamma rays.

When I am wandering the universe looking for interesting galaxies here, I generally start out in optical and find ones that look interesting to me. I then use the different surveys to see how the images change when looking at specific wavelengths.

Now youve had a crash course in galaxy hunting, let the game begin! You can spend hours exploring the incredible images and finding interesting-looking galaxies. I recommend looking at images from DECalS/DR3 for the highest resolution and detail when zooming further in.

The best method is to just drag the sky atlas around. If you find something interesting, you can find out any information we have on it by selecting the target icon and clicking on the object. To help you on your galactic expedition here are my favourite finds of the different types of objects you might see.

Spiral galaxies typically have a central rotating disc with large spiral arms curving out from the denser central regions. They are incredibly beautiful. Our own Milky Way is a spiral galaxy.

Also read: India celebrates birth anniversary of Srinivasa Ramanujam

Elliptical galaxies are largely featureless and less flat then spirals, with stars occupying almost a 3D ellipse at times. These type of galaxies tend to have older stars and less active star-forming regions compared to spiral galaxies.

Lenticular galaxies appear like cosmic pancakes, fairly flat and featureless in the night sky. These galaxies can be thought of as the in between of spiral and elliptical galaxies. The majority of star formation has stopped but lenticular galaxies can still have significant amounts of dust in them.

There are also other amazing types of galaxies, including mergers and lenses, which are just waiting for you to find them.

(Sara Webb, Swinburne University of Technology Melbourne)

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How to explore the universe from our home? - BusinessLine

Beneath Canyons on Mars, Astronomers Find Potentially ‘Water-Rich Area the Size of the Netherlands’ – Smithsonian

A region within Mars's Valles Marineris (pictured) called the Candor Chaoshad a large amount of hydrogen about a meter below the surface. European Space Agency

Located below the Red Planet's equator, the Valles Marineris isone of the largest known series of canyonsin the solar system. About a meter beneath the valley's surface, astronomers have now detected a large amount of hydrogen, reports Michelle Starr forScience Alert. The discovery, published in the journalIcarus,may allow future astronauts to access water on Mars easily.

While water has been previously known to exist on Mars, most of it is found as ice caps near the poles.Water and ice havenever been found at the surface near the equator, however,because temperatures are not cold enough for it to be stable, per astatement. Other missions have looked for surface water hidden as ice on dust particles or locked within minerals.

Researchers at the European Space Agency and the Russian Space Research Institute found evidence of water underneath the cosmic tectonic fracture using the ESA-Roscosmos ExoMars Trace Gas Orbiter (TGO) probe, reports Alex Wilkins forNew Scientist.

Launched in 2016, TGO detected and mapped hydrogen in the top meter of Martian soil using an instrument dubbed Fine Resolution Epithermal Neutron Detector (FREND), reports Meghan Bartels forSpace.com. By detecting neutrons instead of light, the instrument peers through the Red Planet's dust to search for water reservoirs not picked up by other equipment. FREND can measure the hydrogen content of Mars'soil up to a meter below the surface,Science Alertreports.

"Neutrons are produced when highly energetic particles known as 'galactic cosmic rays' strike Mars; drier soils emit more neutrons than wetter ones, and so we can deduce how much water is in a soil by looking at the neutrons it emits," saysco-author Alexey Malakhov, a sceintist at the Space Research Institute of the Russian Academy of Sciences, in a statement.

Using TGO's datafrom May 2018 toFebruary 2021, the team found a large amount of hydrogen beneath the surface ofMars'version of the Grand Canyon, called Candor Chaos. If all of that hydrogen is bound into water molecules, a subsurface regionabout the size of the Netherlandscould beabout 40 percent water, explains the study's lead author Igor Mitrofanov of the Space Research Institute of the Russian Academy of Sciences, who is principal investigator of FREND, in a statement.

"We found a central part of Valles Marineris to be packed full of water far more water than we expected," Malakhov said in a statement. "This is very much like Earth's permafrost regions, where water ice permanently persists under dry soil because of the constant low temperatures."

The water, however, does not appear as abundant liquid lakes found on Earth. Instead, scientists suspectthe Martian dustis riddled with ice or water bonded to minerals,CNN'sAshley Strickland reports. Minerals in this region, however, are not know to contain much water. While ice may seem more likely based on what researchers know about other potential sources of hydrogen on Mars, the temperatures and pressure conditions in the Valles Marineris, situated just below the Martian equator, prohibit the formation of these types of water preserves,Science Alertreports.

There may be special geologic conditions that allow the water to be replenished and remain in this region, CNN reports. Researchers plan on deciphering what type of water lies within the canyon's grooves and how it remains by planning future missions that will focus on lower latitudes in this region.

"Knowing more about how and where water exists on present-day Mars is essential to understand what happened to Mars's once-abundant water, and helps our search for habitable environments, possible signs of past life, and organic materials from Mars's earliest days," saysESA physicistColin Wilsonin a statement.

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Beneath Canyons on Mars, Astronomers Find Potentially 'Water-Rich Area the Size of the Netherlands' - Smithsonian

Abraham Zacuto, the astronomer who predicted an eclipse and saved the life of Columbus – The Times Hub

Home Technology Abraham Zacuto, the astronomer who predicted an eclipse and saved the life of Columbus December 26, 2021

Pedro Choker

Updated:12/26/2021 00:47h

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During the Middle Ages, religion permeated all aspects of society and the different communities learned to live together and share the same spaces. It was not an easy task, especially for the Jewish communities that alternated permissive moments with other intolerant and repressive ones.

This situation was not an obstacle for them to leave us an enormous cultural baggage. In some aljamas science, literature, drama, philosophy, theology experienced a real revolution.

In the Middle Ages, astronomers offered, as a general rule, a product based on astrological prediction, which was not an impediment for them to be used by some monarchs to make serious political decisions.

Portrait of Abraham Zacuto Spanish Foundation for Science and Technology, Eulogia Merle

In the middle of the 15th century, Abraham Zacuto (1452-1515) was born in Salamanca, a distinguished astronomer and mathematician who was called to revolutionize ocean navigation.

He belonged to a family of French exiles, his grandfather fled from the anti-Semitic laws dictated by the Frankish King Philip the Fair and in 1306, after crossing the Pyrenees, he settled on the Castilian plateau.

Abrahams father served as a rabbi on the banks of the Tormes, which allowed him to enjoy a privileged education and develop his scientific concerns. Around 1475 he published Composition Magna a complex work in which they appear astronomical tables, calculated for the Salamanca meridian, which corrected the errors of the Alphonsine Tables.

The interest of Jewish scientists in astronomy was due to the fact that it allowed them to accurately determine the time when the new moon appeared, which marked the beginning of the Sabbath and the beginning of the new year.

Zacuto was a strong defender of the role that astronomy played in the preservation of health, arguing that the signs of the zodiac influenced each of the parts of the body and that their knowledge helped physicists determine the prognosis of some diseases.

In 1492, with the expulsion of the Jews, Zacuto emigrated to Portugal, where King John II appointed him astronomer royal and court historian. His successor to the throne, Manuel I, asked him for advice on an expedition with which he planned to reach India bypassing the southern cone of the African continent.

Apparently the Hebrew gave a favorable opinion while emphasizing that the stars indicated that the success of the company depended on two brothers leading the expedition. It seems that this detail was decisive for Vasco de Gama, the senior captain of the Navy, was chosen, since he had a brother.

It is said that Zacuto prepared the maritime and astronomical calculations that made the expedition possible and that, in addition, he trained the crew in the use of an astrolabe of his creation and that allowed to determine the geographical latitude during navigation.

In 1496 he published a version of the Magna Composition under the title Perpetual Almanac which would enjoy enormous notoriety for more than a century.

The success of the maritime company under the Portuguese flag was not an obstacle so that, in 1497, in the context of a new anti-Semitic wave in Lusitanian lands, he had to emigrate to North Africa, from where he would travel to Damascus, the city that finally saw him. To die.

Christopher Columbus met Zacuto personally and used his maritime tables on the expedition to the Indies. In them the solar declination angle formed by the rays of the sun with the plane of the equator was collected that allowed to determine with enormous precision the position to the equator, without having to resort to the pole star.

During the last Columbian voyage in February 1504, the fleet was left to its own devices in Jamaica, where the natives refused to provide them with food. The Zacuto tables predicted a lunar eclipse for February 29. The admiral gathered the island chiefs and threatened to make the moon disappear if their needs were not met. Apparently the lunar eclipse scared the indigenous people so much that they not only respected the lives of the sailors, but also provided them with everything they asked for.

M. Jara

Pedro Gargantilla is an internist at the Hospital de El Escorial (Madrid) and the author of several popular books.

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UCT astronomers discover first dark cloud without host galaxy – Mail and Guardian

Astronomers at the University of Cape Town (UCT) have discovered a mysterious chain of hydrogen gas clouds.

The dark clouds are the size of a massive galaxy and were discovered through the South African MeerKAT telescope, which the scientists say is proving to be a ground-breaking device in their five-year project to understand galaxy distribution and evolution.

The astronomers say it is the first time they have seen such a massive gas cloud without a host galaxy.

The hydrogen is the fuel for star formation, and so where you have a lot of hydrogen, amassed into a dense object, you have stars or a galaxy of stars, so it is quite a discovery, said professor Thomas Jarrett from UCTs astronomy department.

He said he and his team were going to conduct further studies because such discoveries always lead to a new understanding of nature. The discovery could also provide new insights about galaxy evolution.

The astronomers next move is to figure out how this cloud came to be, and where it is headed.

It could be the detritus from a titanic collision between two galaxies, stripping and separating the gas from the stars. But we really dont see the progenitors, the two or more galaxies that did this. They could be there, just hiding somehow, Jarrett said.

Alternatively, it could be more pristine gas that has been flowing through the filament of the cosmic web, into the attractor that it appears to be aimed.This gravitational attractor is a massive galaxy group. We need deeper MeerKAT observations, and a deeper optical imaging to dig down into the fainter stuff to see if we can discern any gas or star trails that point to a past tidal disturbance, he added.

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UCT astronomers discover first dark cloud without host galaxy - Mail and Guardian

The last spring of the dinosaurs – SYFY WIRE

Sixty-six million years ago, the dinosaurs had a really bad day.

Not just them, either, since 75% of the species on Earth disappeared in a short time. Theres no doubt now that the main driver of this mass murder, called the K-Pg extinction event, was an enormous asteroid (or possibly comet) impact, an object 10 kilometers across that slammed into the planet just off the coast of modern-day Yucatan. This created a crater some 150 kilometers wide, and instigated a series of catastrophic events both immediate and long-term that wiped out most of the life on Earth.

We dont know what the exact date of this event was, but scientists are honing in on the time of year it was, the season. And its looking like life on Earth had a really, really bad June.

Knowing the time of year of the impact is important because of the effect on biology. For example, a species might be more likely to survive if the event happened after they lay their eggs in a protected place. Even if the adults are wiped out a second generation could still have a chance. It also effects how long it might take for plants to regain their place in the environmental niches opened by the impact, or what specific species might dominate in the short term after the impact.

There has been previous work done that points toward the impact happening in late spring/early summer, but there hasnt been a consensus. However, a new paper just published has some pretty good evidence that it was this time of year when the hammer fell.

In the new research, scientists turned to the Tanis fossil site in western North Dakota, a part of the vast Hell Creek Formation, a geological layer that spans several states and is dated to have been laid down at the time of the impact. Some 10 13 minutes after the impact in Mexico, immense seismic waves passed the Tanis site, causing flooding that most likely came from the nearby Western Interior Seaway, a huge but shallow sea that ran north/south across western North America at the time. This in turn created whats called a seiche, a huge standing wave in water that can generate waves a hundred meters high. This is similar, for a much smaller and mundane scale, to when you scooch back and forth in a bathtub in time with the waves generated, amplifying the crests enough that you can splash water out of the tub.

Now picture the tub being a lake, and the waves reaching 20 stories high.

This happened quite suddenly at Tanis, and the geography of the area makes it possible to actually get extremely fine time resolution of the events. Its also replete with fossils, including fish, insects, plants, and more. Heres where this gets cool: By examining these fossils, its possible to figure out the time of year of the impact.

For example, the scientists looked at sturgeon fossils, specifically a pectoral fin spike. Sturgeon are anadromous, which means they migrate from river to sea and back again, so they go from fresh to salty water, and this migration is seasonal. Bone growth in sturgeon depends on time of year, health, and so on, and they can see that the growth of this spike bone stopped suddenly at the tip, certainly due to the fishs death by the impact.

But the key here is in the elemental content of the bone. An isotope of oxygen called oxygen-18 fluctuates in a yearly pattern in the bones corresponding to migration; when the fish is in fresh water theres not as much oxygen-18, and when theyre in salty seawater it is incorporated more strongly. The opposite is true for an isotope of carbon called carbon-13; its absorption in the bone is heavier in fresh water and lighter in seawater.

The scientists saw these abundances going up and down in the fish bone as they traced them toward the tip, and theyre out of phase (when one goes up the other goes down, and vice-versa), a clear indication of the seasons. Plotting these fluctuations, the scientists found the impact happened in late spring or early summer.

They found the same thing in mayflies. These insects burrow into wood to lay eggs, which hatch during a very brief interval of less than a few weeks in early spring. The fact that adult mayflies were found fossilized shows that the impact happened while adult mayflies were active, so after the eggs hatched. The bodies are also fragile, so the impact must have happened early in their adulthood, or else intact fossils wouldnt have been found.

On top of that, some insect larvae eat leaves, leaving characteristic tracks in the leaves (this is called leaf-mining, an adorable term). Intact furrows in some fossilized leaves including some still attached to branches show that larvae were actively feeding at the time of impact, again pointing toward spring/summer, when larvae are busy building mass for metamorphosis.

I find this all rather amazing. I remember when the asteroid impact hypothesis was very controversial, and now its not only accepted, but evidence has popped for it in unlikely events like a million-year-long volcanic eruption halfway around the planet due to the force of impact opening up underground magma pipes, allowing the eruption to increase (though the contribution of this to mass extinctions is still being argued over).

And now not only is it accepted, but scientists can narrow down what month it happened in.

Big asteroid impacts are exceptionally rare, and global mass extinctions from them even more so. Still, the more we know about such events the better. You never know what piece of evidence will lead to a discovery that helps us better prevent an impact, or understand what the consequences are if we dont.

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New synthetic opioid threatens to drive up astronomical overdose rates – Washington Examiner

A deadly new class of synthetic opioids has been identified in cities throughout the United States at a time when fatal drug overdose rates are soaring.

Forensic scientists have identified nitazenes on streets throughout the country. The nitazene class has proven even stronger than fentanyl, the synthetic opioid the extreme potency of which is responsible for the majority of deadly overdoses in the U.S.

There's probably about five to 10 drugs that make up this medicine class right now that have been identified on the market, said Alex Krotulski, an expert in nitazenes at the Center for Forensic Science. They're really spread through all areas throughout the U.S. Usually, we see them epicentered around places in the Midwest and then, they sort of proliferate out from there.

DOCTORS CAUTION CDC AGAINST CHANGING 'FULLY VACCINATED' STANDARD FOR NOW

The most commonly found drugs within the nitazene class are isotonitazene, metonitazene, and protonitazene, which have been found in many states such as Texas, Ohio, Indiana, New York, and New Jersey. Experts estimate the potency of the nitazene class to range from twice to 10 times as fatal as fentanyl, which is sometimes undetectably laced in heroin or cocaine and can be fatal in even miniscule doses.

The majority of these nitazene analogs are more potent than fentanyl, especially the ones that we see. I think that's probably by design, Krotulski said. You've got drugs that are, say, one to two times more potent than fentanyl, that are two to three times more potent, and now you've got drugs that are 10 times more potent than fentanyl.

The onset of the pandemic in Spring 2020 brought with it mandatory quarantines and social distancing, conditions that facilitated skyrocketing drug overdoses. The Centers for Disease Control and Prevention reported in July that fatal drug overdoses in 2020 increased by nearly 30% over the previous year, reaching an all-time high of more than 93,300. Opioids were the cause of a majority of overdose deaths in every state as well as D.C. Fatal overdoses caused by opioids specifically increased from 50,963 in 2019 to an estimated 69,710 in 2020.

Fentanyl and other synthetic opioids were involved in more than 60% of all fatal drug overdoses in 2020. Drug users who misuse nitazenes will often use them in concert with another substance, sometimes unknowingly. Drugs such as heroin or cocaine are often laced with trace amounts of extremely potent synthetic opioids to make them cheaper to traffic.

"Nowadays with the overdose epidemic, we're seeing a lot more poly drug use so you have to examine the drugs by themselves ... Then you also have to take into account the fact that these drugs are being found and used with fentanyl. And when you get into that scenario, you're just adding things together, adding potent on top of potent," Krotulski said.

Versions of fentanyl that have been chemically altered to be more potent, also called fentanyl analogs, have increased in popularity in recent years due to the governments whack-a-mole-like approach to regulating the synthetic drugs. Since 2018, all fentanyl analogs have been categorized as schedule 1 substances, meaning they have extremely high abuse potential and no medical benefit.

When a drug is scheduled with the Drug Enforcement Administration and becomes harder to find, a newer drug takes its place. Enter: nitazenes.

We're seeing the same thing happen where with fentanyl analogs, one drug would be prevalent, it would be scheduled by the DEA, that drug would go away, and then a new drug would be introduced into the market, Krotulski said. So, we're seeing this sort of cyclic pattern, if you will, of one drug after another after another after another.

The synthetic opioids have also been identified in the District of Columbia, where opioid overdose deaths in the 12 months leading up to May 2021 reached about 498. D.C. ranks second behind West Virginia in the number of deaths due to opioid overdoses during the pandemic, according to an analysis from the Washington Post. Alexandra Evans, a chemist at the D.C. Public Health Lab was the first in the district to identify the drugs after finding residue on a used needle collected from the citys needle exchange locations for intravenous drug users to discard used paraphernalia and get new supplies.

We knew that it was a new type of synthetic opioid very quickly, based on its instrumental analysis report, Evans said. Our lab had heard about the discovery of nitazenes in other cities beginning in 2019. We were familiar with this drug class, and the specific drugs within it.

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The stress of COVID-19 and social isolation have contributed to the roughly 4 in 10 adults in the U.S. who have experienced increased rates of anxiety and depression, according to the Kaiser Family Foundation. Stay-at-home orders during the first wave of COVID-19 also made visiting with or checking in on people suffering with substance use disorders difficult and sometimes impossible.

COVID-19 has been difficult to track, and surges have been difficult to predict. The recent discovery of the omicron variant has concerned public health experts and healthcare workers who are still reeling from roughly 20 months of overcrowded ICUs and strained supplies. While the Biden administration has not indicated it will revert back to early pandemic restrictions such as business closures or stay-at-home orders, the U.S. will continue to beat back renewed surges into next year.

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New synthetic opioid threatens to drive up astronomical overdose rates - Washington Examiner

Tulane Professor Elected to National Academy of Inventors – bizneworleans.com

Chenzhong Li is a pioneer in the development of biosensors for cancer, neurological diseases and infectious disease diagnosis and treatment. He holds 16 U.S. and international patents with several more pending. (Photo by Paula Burch Celentano.)

NEW ORLEANS From Tulane University:

Tulane University professor Chenzhong Li, PhD, has been named a 2021 fellow by the National Academy of Inventors (NAI), an honor that is the highest professional distinction accorded solely to academic inventors.

Li, professor of Biomedical Engineering and Biochemistry at Tulane University School of Medicine and the School of Science and Engineering, leads advances in biochemistry and biomedical engineering research at the Center for Cellular and Molecular Diagnostics. He was one of 164 prolific academic innovators from across the world elected as an NAI Fellow this year.

The NAI Fellows Program highlights academic inventors who have demonstrated a spirit of innovation in creating or facilitating outstanding inventions that have made a tangible impact on the quality of life, economic development and the welfare of society.

I am delighted to be selected for a fellowship with the National Academy of Inventors, Li said. This is an amazing moment and one of the most important in my professional career. While I have only been a part of the Tulane family for a relatively short amount of time, this recognition gives me the inspiration to improve my work even more in translational research and entrepreneurship education for our faculty and students.

Li is a pioneer in the development of biosensors for cancer, neurological diseases and infectious disease diagnosis and treatment. He holds 16 U.S. and international patents with several more pending.

Li developed a carbon fiber micro biosensor array only a few micrometers in size to find Beta-amyloid proteins, a critical biomarker for Alzheimers disease. The needle-like nano biosensor can measure the biomarker at the single neuron level to help better understand Alzheimers progression and to fast screen potential drug treatments. He has also invented new technology using nanoparticles to find markers for cancer tumor growth.

Li has also worked as a professional research associate at the startup company Adnavance Technologies, Inc. in Canada where he led an entrepreneurial effort in developing DNA biosensors for the detection of DNA mutations and DNA binding drug screenings.

Since joining Tulane in February, Li has worked with Tony Hu, PhD, the Weatherhead Presidential Chair in Biotechnology Innovation, and his lab to develop advanced diagnostics for infectious diseases including COVID and tuberculosis.

The caliber of this years class of NAI Fellows is outstanding. Each of these individuals are highly-regarded in their respective fields, said Dr. Paul R. Sanberg, FNAI, President of the NAI. The breadth and scope of their discovery is truly staggering. Im excited not only see their work continue, but also to see their knowledge influence a new era of science, technology, and innovation worldwide.

The 2021 Fellow class hails from 116 research universities and governmental and non-profit research institutes worldwide. They collectively hold over 4,800 issued U.S. patents. Among the new class of Fellows are 33 members of the National Academies of Sciences, Engineering, and Medicine, and three Nobel Laureates, as well as other honors and distinctions. Their collective body of research and entrepreneurship covers a broad range of scientific disciplines involved with technology transfer of their inventions for the benefit of society.

To date, NAI Fellows hold more than 48,000 issued U.S. patents, which have generated over 13,000 licensed technologies and companies, and created more than one million jobs. In addition, over $3 trillion in revenue has been generated based on NAI Fellow discoveries.

The National Academy of Inventors is a member organization comprising U.S. and international universities, and governmental and non-profit research institutes, with over 4,000 individual inventor members and Fellows spanning more than 250 institutions worldwide. It was founded in 2010 to recognize and encourage inventors with patents issued from the United States Patent and Trademark Office, enhance the visibility of academic technology and innovation, encourage the disclosure of intellectual property, educate, and mentor innovative students, and translate the inventions of its members to benefit society.

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Tulane Professor Elected to National Academy of Inventors - bizneworleans.com

The Role of Nanomedicine in Transdermal Vaccine Alterantives – AZoNano

The World Health Organization has estimated the SARS-CoV-2 (COVID-19) pandemic to have caused more than 5.3 million deaths worldwide to date, and with the emergence of new variants, the urgency of effective immunization has never been more critical.

Study:The Importance of Nanocarrier Design and Composition for an Efficient Nanoparticle-Mediated Transdermal Vaccination. Image Credit:BaLL LunLa/Shutterstock.com

Alternative means of effective delivery have been explored in a recently published article from the journal vaccines, highlighting how nanomedicine can aid the effectiveness oftransdermal antigen delivery.

The COVID-19 infection caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2) has been catastrophic for the global population, with high rates of morbidity and mortality.

Schematic representation of the routes of skin penetration of active compounds. On the left, a transpedicular route consists of a. entry through hair follicle, b. entry through sweat glands, c. entry through sebaceous glands. On the right, transepidermal route. d. Transcellular pathway, e. Intercellular pathway.Image Credit:Valdivia-Olivares, R.,et al

The World Health Organization has estimated approximately 19.4 million infants globally have not been provided with vaccines. As the severity of the pandemic continues, the health of these children is at increased risk for deterioration.

This has led to the need to find alternative routes for immunization, which are effective and safe.

Transdermal routes of antigen delivery consist of a topical application to the skin where the active ingredients are absorbed systemically.

This type of method can be beneficial as it reduces first-pass metabolism and reduces the level of adverse effects. Transdermal administration provides an easy, simple, non-traumatic alternative that allows for self-administration, making this delivery route more attractive than the traditional injection method that involves needles.

However, a challenge for this delivery route for vaccine development consists of the protective barrier of the skin and the associated difficulties with overcoming the stratum corneum to enable antigen absorption.

Schematic representation of the mechanisms involved in immunization based on nanoparticles, either using combined techniques or design of nanoparticles by passive diffusion. Once the stratum corneum has been crossed, the antigens can interact with cells of the immune system already described. Image Credit:Valdivia-Olivares, R., et al

The skin is the largest organ in the body and consists of up to 20 million cell types, comprising but not limited tokeratinocytes, Langerhans cells, dendritic cells, T cells, and mast cells. These cells hold critical functions in the skin, contributing to immunocompetence and preventing pathogens from entering.

However, this also would prevent antigen delivery in the circumstance of vaccine development. Overcoming the stratum corneum barrier for transdermal permeability has been a focal point for researchers who have developed innovative technologies, such as iontophoresis, sonophoresis, and magnetophoresis electroporation, and laser microporation.

These methods can be effective but have their own limitations. For example, they are economically inefficient, and due to this, the most ubiquitous method for the administration of micro- and macromolecules via the skin has been the use of microneedles.

While microneedles can be effective, it is not considered to be completely needle-free and so with the emergence of the innovative field of nanotechnology, optimized nanosystems have been developed to cross the skin barrier without the dependence on invasive techniques.

Nanosystems which have been used for antigen delivery have been researched within literature and include nanoparticles and liposomes. Liposomes can be utilized effectively to transport antigens within parenteral administration;however, their use for needle-free transdermal immunization can be less effective.

This is due to their rigid structure which makes them inefficient for crossing the skin barrier, though incorporating nanotechnology within this nano-sized delivery particle, can allow this obstacle to be overcome.

Transferosomes are elastic liposomes that consist of phospholipidsthat form deformable vesicles. This mode of antigen delivery can be promising for use within the transdermal route as these particles can increase transdermal permeability in the stratum corneum in the presence of a hydration gradient.

Intriguingly, the biological makeup of transferosomes includes being highly flexible, effective for encapsulating hydrophobic and hydrophilic compounds as well peptides, and most importantly, they can pass through the pores of the skin. These key characteristics make transferosomes a perfect candidate for needle-free antigen delivery.

While there are significant benefits utilizing nanosized particles for nanovaccine development in innovative alternatives for parenteral antigen delivery within vaccinations, this area still requires further research.

Nanomedicine has innovated several fields of medicine, and this has benefitted research into the quality of patient care; however, the current state of medicine has proven immunizations of entire populations to be the most cost-effective method in disease prevention. This route can only be challenged with a collaborative effort with production laboratories to reduce production costs.

The advancement of needle-free administration would also require further research into the size and stability of nanosystems and the optimization of strategiesto tackle designs in a short space of time with limited resources, such as through utilizing computational techniques. This would be beneficial within a pandemic where resources are being shared between countries and urgent demand for solutions.

Benefitting and improving patient care should be the highest priority of medicine and with advanced nanocarrier design and innovative researchers, transdermal vaccinations could potentially become the future of disease control.

Continue reading: Antiviral Activity of Intermetallic Nanoparticles Incorporated into Polymeric Fibers.

Valdivia-Olivares, R., Rodriguez-Fernandez, M., lvarez-Figueroa, M., Kalergis, A. and Gonzlez-Aramundiz, J., (2021)The Importance of Nanocarrier Design and Composition for an Efficient Nanoparticle-Mediated Transdermal Vaccination.Vaccines, 9(12), p.1420. Available at: https://www.mdpi.com/2076-393X/9/12/1420

Gheibi Hayat, S. and Darroudi, M., (2019)Nanovaccine: A novel approach in immunization.Journal of Cellular Physiology, 234(8), pp.12530-12536. Available at: https://doi.org/10.1002/jcp.28120

Disclaimer: The views expressed here are those of the author expressed in their private capacity and do not necessarily represent the views of AZoM.com Limited T/A AZoNetwork the owner and operator of this website. This disclaimer forms part of the Terms and conditions of use of this website.

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The Role of Nanomedicine in Transdermal Vaccine Alterantives - AZoNano

MagForce AG: Enrollment in Stage 2b of Pivotal U.S. Study for the Focal Ablation of Prostate Cancer with the NanoTherm Therapy System successfully…

DGAP-News: MagForce AG / Key word(s): Study20.12.2021 / 08:30 The issuer is solely responsible for the content of this announcement.

MagForce AG: Enrollment in Stage 2b of Pivotal U.S. Study for the Focal Ablation of Prostate Cancer with the NanoTherm Therapy System successfully underway following IRB approval

Berlin, Germany and Nevada, USA, December 20, 2021 - MagForce AG (Frankfurt, Scale, Xetra: MF6, ISIN: DE000A0HGQF5), a leading medical device company in the field of nanomedicine focused on oncology, together with its subsidiary MagForce USA, Inc., announced today that enrollment of patients in Stage 2b of its pivotal U.S. study with the NanoTherm therapy system for the focal ablation of intermediate risk prostate cancer is successfully proceeding.

Following FDA approval to initiate Stage 2b with the final study protocol in November, MagForce USA, Inc. has since received the green light from the ethics commission ("Institutional Review Board", IRB) to proceed with the study at the respective centers. After IRB approval, MagForce has now enrolled the first patients into the clinical trial while continuing to reach out to pre-identified potential study participants for updated testing and preparations. Up to 100 men diagnosed with intermediate risk prostate cancer that has progressed to a stage where a clinical review and treatment change is required will be enrolled at the NanoTherm treatment centers owned and operated by MagForce.

"We are happy that enrollment in Stage 2b of our pivotal US study has successfully commenced and that the recruitment process is progressing well, despite once again surging Covid-19 cases. Stage 2b builds on the positive findings of earlier studies which demonstrated safety and efficacy of our approach and importantly, showed no treatment-related side effects frequently experienced with other therapies, such as sexual, urinary or gastrointestinal dysfunction or loss of energy. We are excited about the trials' potential results and are hopeful to be able to provide prostate cancer patients with a minimally invasive and highly accurate treatment option," said Ben Lipps, CEO of MagForce AG and MagForce USA, Inc.

Stage 2b of the single-arm pivotal study is planned to evaluate the use of NanoTherm ablation for the treatment of prostate cancer patients with intermediate grade lesions and confirm the favorable results seen in Stage 2a in a larger patient population. The trial is designed to demonstrate that the NanoTherm therapy system can focally ablate targeted prostate cancer lesions with minimal side effects. Subsequently the patients should then be able to return to active surveillance without definitive treatment, such as external beam radiation or prostatectomy.

MagForce previously reported encouraging findings from Stage 1 and 2a of its pivotal study confirming a highly favorable safety and tolerability profile. Treatment with the NanoTherm therapy system showed no unanticipated serious adverse events but only minimal treatment-related side effects, which were tolerable and similar to those commonly associated with biopsies.

Based on the current plan and conditions set out by the FDA, the clinical trial is expected to be finished in summer 2022. Following the final protocol, MagForce will submit interim data packages at 15 and 30 patients treated for FDA review, whilst treatments continue, which will be updated and submitted for approval after trial completion.

About MagForce AG and MagForce USA, Inc.

MagForce AG, listed in the Scale segment of the Frankfurt Stock Exchange (MF6, ISIN: DE000A0HGQF5), together with its subsidiary MagForce USA, Inc. is a leading medical device company in the field of nanomedicine focused on oncology. The Group's proprietary NanoTherm therapy system enables the targeted treatment of solid tumors through the intratumoral generation of heat via activation of superparamagnetic nanoparticles.

NanoTherm(R), NanoPlan(R), and NanoActivator(R) are components of the therapy and have received EU-wide regulatory approval as medical devices for the treatment of brain tumors. MagForce, NanoTherm, NanoPlan, and NanoActivator are trademarks of MagForce AG in selected countries.

For more information, please visit: http://www.magforce.com Get to know our Technology: video (You Tube)Stay informed and subscribe to our mailing list

Disclaimer

This release may contain forward-looking statements and information which may be identified by formulations using terms such as "expects", "aims", "anticipates", "intends", "plans", "believes", "seeks", "estimates" or "will". Such forward-looking statements are based on our current expectations and certain assumptions, which may be subject to a variety of risks and uncertainties. The results actually achieved by MagForce AG may substantially differ from these forward-looking statements. MagForce AG assumes no obligation to update these forward-looking statements or to correct them in case of developments, which differ from those, anticipated.

Contact:MagForce AG, Max-Planck-Strasse 3, 12489 BerlinBarbara von Frankenberg,VP Communications & Investor RelationsP +49-30-308380-77M bfrankenberg@magforce.com

20.12.2021 Dissemination of a Corporate News, transmitted by DGAP - a service of EQS Group AG.The issuer is solely responsible for the content of this announcement.

The DGAP Distribution Services include Regulatory Announcements, Financial/Corporate News and Press Releases.Archive at http://www.dgap.de

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MagForce AG: Enrollment in Stage 2b of Pivotal U.S. Study for the Focal Ablation of Prostate Cancer with the NanoTherm Therapy System successfully...

The Top 10 Technology and Business Trends of 2022 – Inc.

As Covid-19 vaccinations increase globally, life is getting back to normal. However, it's no longer the world we experienced before the pandemic. The long-term nature of this global crisis has changed customer needs and daily lifestyles. This will, in turn, change what I expect the world to look like in 2022 and beyond. Let's review the top 10 technology and business trends that we'll likely encounter in the coming year.

Momentum in Life Science Technologies

The life science industry comprises pharmaceuticals,biotechnology, environmental sciences, biomedicine, nutraceuticals, neuroscience, cell biology, and biophysics. Partially because ofincreased investments in mRNA vaccine technology and high-performance Covid-19 testing, 2021 has driven great innovation in life science technologies.

Examples of this innovation include the mRNA-based vaccines developed by Pfizer-BioNTech and by Moderna. Recent Covid drug developments by Merck have also pushed the life science industry forward rapidly.

Looking ahead, I expect we'll see strong movement in the several life science sectors, including advanced research; application of robotics technology; artificial intelligence (A.I.) tools; use of cloud technology; the improvement of drug testing speed; integration of genetic information; and usage of gene technology. I also foresee the development of personalized medicine through advancements in genetics technology. The startup 23andMe, for example, helps people access, understand, and benefit from the human genome.

Networking and Interconnectivity: Expansion of 5G-6G and Satellite-Based Internet Usage

As remote working becomes commonplace, internet reliability becomes more vital than ever. The internet of things (IoT) makes the internet a more integral part of our lives, and developments at all network levels will continue to drive research and push the internet economy forward.

According to Cisco's Visual Networking Indexforecast update for 2018, there will be 1.4 billion more people using the internet by 2022, compared with 3.4 billion users in 2017. This equates to almost 60 percentof the global population, assuming a population of eight billion by 2022. By then, internet users are expected to consume 4.8 zettabytes of data per year, 11 times the amount of IP traffic generated in 2012, with 437 exabytes.

While 5G may be in its infancy, we'll see an increased focus on 6G in 2022. China started research into 6G in 2018. By late 2020, the country had launched a satellite to test terahertz signal transmission. Huawei and ZTE were involved. The U.S. also started 6G research in 2018 with the Federal Communications Commission (FCC) opening higher frequency spectrum for experimental use. A Next G Alliance was started in 2020, with companies on board including Apple, AT&T, and Google. Korea, Japan, and some European countries have started looking into 6G seriously, and we expect to see more announcements in 2022.

High-Performance Computing Becomes Mainstream

Given the recent growth of big data-based research and analysis and cloud-based computing, I expect high-performance computing usage to surge in 2022. From drug discovery to cancer research to space exploration, high-performance computing will become increasingly important, and quantum computing technology needs to keep up with business demand.

We've already seen massive development in quantum computing space by players including Google, IBM, Microsoft, Amazon, and Alibaba. Startups such as Rigetti Computing, D-Wave Systems, ColdQuanta,1QBit, Zapata Computing, and QC Ware have exceeded the industry expectations in their technology and their growth.

I expect rapid progress in quantum computing during 2022, because the high demand for larger machine power is going to accelerate development in this sector.We'll likely see announcements of large qubit developments in the new year. Commercial quantum computing will soon be within our reach, and new breakthroughs will occur at an accelerated pace.

Continued Growth in Artificial Intelligence, Big Data Analytics, and Cloud Computing

A.I. has become an integral part of our lives. From improvements to personalization, ranking search results, recommending products, and understandingand controlling devices tobuilding better models of the environment to automatingindustry, we see the application of artificial intelligence everywhere as we look toward 2022.

Organizations are using predictive analytics to forecast future trends. According to a report published by Facts & Factors, the global predictive analytics market is growing at a compound average growth rate of around 24.5 percentand is expected to reach $22.1 billion by the end of 2026.

We will also see massive growth in cloud computing. By 2022, the cloud will be more entrenched and more computing workloads will run on the cloud. The internet of things will push this space in a bigger way, for sure. According to predictions from Gartner, global spending on cloud services is expected to reach over $482 billion in 2022, up from $314 billion in 2020.

Internet Security and Privacy Dominate

As the world becomes more digital, we're seeing an increased number of personal and organizational cyberattacks around the world. Several corporations have been the target of major cyberattacks in recent days, and businesses have become more vulnerable to destructive attacks, in part because ofincreased remote work giventhe pandemic.

During 2022, I expect that we'll see cyberattacks across sectors, and we will see the industry take a variety of counteractive measures. Defending against cyberattacks will include educating individuals so they can identify and avoid network assaults, thereby safeguarding their company's image.

Applying A.I. will make robust cybersecurity protocols easier andless expensive to createand more effective than ever. Use of A.I. can enable cybersecurity to spot risks and learn the behaviors of cybercriminals, thus preventing prevent future attacks. It can also help cut down on the time it takes cybersecurity specialists to do their daily tasks.

The MetaverseWill Shine in 2022

The metaverse is a digital reality combining social media, online gaming, augmented reality, virtual reality, and cryptocurrencies to allow virtual user interaction. The metaverse may refer to anything on the internet, including all of AR's offerings. Virtual space of the future describes the metaverse, providing access to all kinds of entertainment and projects, including the opportunity to work.

We expect the metaverse to be immersive, ubiquitous, and free to access. It will be digitally focused, and potentially involves entertainment, social connection, work productivity, and behavior modification at scale. It will create an entire ecosystem for developers, apps, ads, and new digital innovations. The metaverse will facilitate convenience, consumption, and a frictionless access to services.

Only a few companies today have a real stake in the metaverse. They include ByteDance, Tencent, Facebook, Spotify, Zoom, Amazon (Twitch), Alibaba, Roblox, Bilibili, Snapchat, Kuaishou, and Huawei. Apple's wearables also point to the metaverse with AR glasses coming soon. Microsoft with Microsoft Teams and gaming is perhaps the most advanced company in the world regarding the metaverse. WeChat's ability to facilitate payments and access to a variety of services is the start of the metaversesuper apps.

As the metaverse ecosystem grows in 2022, I expect it will have a direct impact on the future of many technology sectors. These include gaming, wearables, VR and AR, collaborative productivity (Canva, Slack), consumer tech products (including AR glasses or smart speakers), social networks, educational technology, health technology, communication technology (Zoom), digital currencies, and convenience mobilization and on-demand consumption (Amazon, Meituan, Alibaba, JD.com, Shopify).

NFT Platforms Will Boom

A non-fungible token (NFT) is a digital object: computer code and data that conveys ownership of something. The property may be online:for example, virtual real estate in the digital world or special equipment in a video game. Or it could be real: real estate, a painting, or a seat at a concert. An NFT can also be a hybrid:for example, the right to decide who can rent a room in a cooperative living space. A baseball card, Ronaldo's first ball, a vintage car, or a piece of land in Central London: All are one of a kind and can be transferred to the NFT.

In 2022, we are likely to see NFTs everywhere; this includes in movies, TV shows, books, and more. NFTs are part of the digital economy and are becoming mainstream because they allow people to own something that represents a part of something bigger than themselves -- a piece of art or a character, for example. The digital economy is made up of a variety of online markets, including game economies, virtual real estate, and even social media platforms like Facebook.

Our society has changed rapidly over the past decade, especially because of the 2008 to 2009 economic crisis and the pandemic. These trends are coming together to shape a world where NFTs will beat traditional collectibles, making 2022 a tremendous year.

The Robotics Sector Will Become More Prevalent

We expect to see an increased use of robotics in everyday life during 2022. Usage will include the health care, agriculture, automotive, warehousing, and supply chain management sectors, and we will see more robotics-based automation that will continue to progress.

The Covid-19 pandemic presents both problems and opportunities forroboticscompanies in the logistics and supermarket industries. Unexpected strains on supply systems and product shortages have highlighted the need for better supply chain efficiency. It's also become obvious thatrobotsand automation providea safe means for manufacturers to keep employees socially separated yet allow the business to continue operating.

The use of robotics process automation (RPA) helps automate activities that are performed repeatedly; we expect RPA to grow in 2022 and become a standard technology for business. CIO reports that chief information officers are using RPA to free workers from boring, repetitive tasks and allow them to do more fulfilling work. Finally, we're seeing a rise in nanorobotics, tiny sensors with limited processing power. The first useful applications of these nano-machines may be in nanomedicine. Biological machines, for example, are used to identify and destroy cancer cells or deliver drugs.

Increased Urgency in the Renewable Energy Technology Sector

Climate change and dramatic news headlines are driving rapid growth in sustainable energy adoption. During the pandemic, this has been the only energy sector that has grown. According to the International Energy Agency (IEA), 40 percentmore green energy was generated and used in 2020; the agency expects continued growth in 2022. The falling costof generating sustainable energy also helps ensure that mass adoption is likely. While newer energy technologies like nuclear fusion, biofuel, and liquid hydrogen might take longer to come full circle, we look forward to serious advancements in 2022.

I also expect to see massive growth in the production and usage of solar and wind technology. Storage (battery) technologies are playing a larger role, since there will be an increased need to store renewable energy.

Blockchain Technology Prevails

Blockchain, an innovative breed of distributed ledger, enables companies to track a transaction and do business with unverified parties -- even without the assistance of financial institutions. This new capability significantly lessens business conflicts; it also adds other benefits such as append-only data structure, transparency, security, immutability, and decentralization.

Blockchain technology has enjoyed massive adoption and continues to disrupt many industries, from gaming and governance to finance. According to the International Data Corporation, companies will spend almost $6.6 billion on blockchain solutions in 2021, a 50 percentincreasefrom the previous year. This number is expected to grow beyond $15 billion in 2024. With the new rise of NFTs and themetaverse, blockchain will become more important in 2022.

Businesses are encouraged to start studying blockchain technology, since it is expected to generate significant business opportunities; Statista reports that global blockchain technology is predicted to grow to more than $23.3 billion by 2023. A notable existing blockchain deployment is that of Walmart's supply chain database application, allowing the monitoring of individual products directly to their very source, effectively elevating food supply standards. Amazon is rolling out its blockchain initiatives for 2019, which allow its Amazon Web Services clients to benefit from distributed ledger solutions.

Looking Ahead

There's little doubt that 2022 will see rapid progress in these and other technologies, as the world emerges from the Covid-19 pandemic. I see a prime opportunity for smart startups, corporations, and investors to capitalize on these emerging technology and business trends to become more successful than ever. Let's hope that the resulting innovation makes the world better for people and businesses.

The opinions expressed here by Inc.com columnists are their own, not those of Inc.com.

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The Top 10 Technology and Business Trends of 2022 - Inc.

PhD within Development of Amine-Based nanofluids with Improved CO2 Capture Performance job with NORWEGIAN UNIVERSITY OF SCIENCE & TECHNOLOGY -…

About the position

We have a vacancy for a PhD candidate position within theParticle Engineering Centreat the Department of Chemical Engineering.

For a position as a PhD Candidate, the goal is a completed doctoral education up to an obtained doctoral degree.

TheParticle Engineering Centreat the Department of Chemical Engineering at NTNU was established in early 2021. The basis for the research in the Centre is an extensive experience at the department within particle synthesis and characterization, which quite recently was put into practical application as part of the COVID-19 test method developed at NTNU. The objective of the Centre is to advance the scientific knowledge within fundamental and applied particle engineering. Ongoing research activities focus on synthesis, characterization and tailoring of particles for use in nanomedicine and environmental applications.

The proposed PhD project aims to improve CO2 absorption efficiency of conventional amine solvents by developing their corresponding nanofluids. A comprehensive study is planned to prepare stable nanofluids with optimal thermophysical properties and to examine their effects on mass transfer kinetics and overall CO2 absorption performance under conditions resembling real CO2 capture plants.

You will report to your supervisor.

Duties of the position

The PhD research work will involve:

The candidate is further expected to:

Required selection criteria

The appointment is to be made in accordance with the regulations in force concerning State Employees and Civil Servants andRegulations concerning the degrees of Philosophiae Doctor (PhD) and Philosodophiae Doctor (PhD) in artistic research national guidelines for appointment as PhD, post doctor and research assistant

Preferred selection criteria

Personal characteristics

We offer

Salary and conditions

PhD candidates are remunerated in code 1017, and are normally remunerated at gross from NOK 491 200 per annum before tax, depending on qualifications and seniority. From the salary, 2% is deducted as a contribution to the Norwegian Public Service Pension Fund.

The period of employment is 3years.

Appointment to a PhD position requires that you are admitted to the PhD programme inChemical Engineeringwithin three months of employment, and that you participate in an organized PhD programme during the employment period.

The engagement is to be made in accordance with the regulations in force concerning State Employees and Civil Servants, and the acts relating to Control of the Export of Strategic Goods, Services and Technology. Candidates who by assessment of the application and attachment are seen to conflict with the criteria in the latter law will be prohibited from recruitment to NTNU. After the appointment you must assume that there may be changes in the area of work.

The position is subject to external funding.

It is a prerequisite you can be present at and accessible to the institution daily.

About the application

The application and supporting documentation to be used as the basis for the assessment must be in English.

Publications and other scientific work must follow the application. Please note that applications are only evaluated based on the information available on the application deadline. You should ensure that your application shows clearly how your skills and experience meet the criteria which are set out above.

The application must include:

If all, or parts, of your education has been taken abroad, we also ask you to attach documentation of the scope and quality of your entire education, both bachelor's and master's education, in addition to other higher education. Description of the documentation required can be foundhere. If you already have a statement from NOKUT, please attach this as well

Joint works will be considered. If it is difficult to identify your contribution to joint works, you must attach a brief description of your participationand personal and interpersonal qualities. Motivation, ambitions, and potential will also count in the assessment of the candidates.

NTNU is committed to following evaluation criteria for research quality according toThe San Francisco Declaration on Research Assessment - DORA.

General information

Working at NTNU

A good work environment is characterized by diversity. We encourage qualified candidates to apply, regardless of their gender, functional capacity or cultural background.

The city of Trondheimis a modern European city with a rich cultural scene. Trondheim is the innovation capital of Norway with a population of 200,000. The Norwegian welfare state, including healthcare, schools, kindergartens and overall equality, is probably the best of its kind in the world. Professional subsidized day-care for children is easily available. Furthermore, Trondheim offers great opportunities for education (including international schools) and possibilities to enjoy nature, culture and family life and has low crime rates and clean air quality.

As an employeeatNTNU, you must at all times adhere to the changes that the development in the subject entails and the organizational changes that are adopted.

Information Act (Offentleglova), your name, age, position and municipality may be made public even if you have requested not to have your name entered on the list of applicants.

If you have any questions about the position, please contact Professor Jana Poplsteinova Jakobsen, emailjana.p.jakobsen@ntnu.no. If you have any questions about the recruitment process, please contact HR-Consultant Unni M. Myhre, e-mail:unni.m.myhre@ntnu.no

Please submit your application electronically via jobbnorge.no with your CV, diplomas and certificates. Applications submitted elsewhere will not be considered. Diploma Supplement is required to attach for European Master Diplomas outside Norway. Chinese applicants are required to provide confirmation of Master Diploma fromChina Credentials Verification (CHSI).

If you are invited for interview you must include certified copies of transcripts and reference letters. Please refer to the application number 140/2021 when applying.

Application deadline: 10.01.2022

NTNU - knowledge for a better world

The Norwegian University of Science and Technology (NTNU) creates knowledge for a better world and solutions that can change everyday life.

Department of Chemical Engineering

We take chemistry from laboratory scale to industrial production. This demands a wide range of knowledge, from molecular processes and nanotechnology to building and operation of large processing plants. We educate graduates for some of Norway's most important industries. The Department of Chemical Engineering is one of eight departments in the Faculty of Natural Sciences.

Deadline10th January 2022EmployerNTNU - Norwegian University of Science and TechnologyMunicipalityTrondheimScopeFulltimeDurationTemporaryPlace of serviceGlshaugen

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PhD within Development of Amine-Based nanofluids with Improved CO2 Capture Performance job with NORWEGIAN UNIVERSITY OF SCIENCE & TECHNOLOGY -...

Human reproduction – Reproduction – KS3 Biology – BBC …

The female reproductive system has two ovaries (singular: ovary). These have two functions:

Each ovary is connected to the uterus by an oviduct.. The oviduct is lined with cilia, which are tiny hairs on cells. As part of the menstrual cycle, an ovum develops, becomes mature and is released from an ovary. The cilia move the ovum along the oviduct and into the uterus.

The uterus is a muscular bag with a soft lining. The uterus is where a baby develops until birth. The cervix is a ring of muscle at the lower end of the uterus. It keeps the baby in place during pregnancy.

The vagina is a muscular tube that leads from the cervix to the outside of the body. A penis goes into the vagina during sexual reproduction. This is also where menstrual blood leaves the body and where a baby exits during birth.

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Human reproduction - Reproduction - KS3 Biology - BBC ...

Women empowerment in reproductive health: a systematic review of measurement properties – BMC Women’s Health – BMC Blogs Network

Study characteristics

The search strategy yielded 5234 relevant records. Finally, 62 full texts were reviewed, of which 15 separate scales were identified (Fig.1).

PRISMA flow diagram of study process

Ambiguous scales that measured the components, dimensions, or subscales of women empowerment but did not fit in our framework and original search strategy were excluded to consistently adhere to our conceptual framework (n=46). Another full text aimed at the psychometric analysis of Reproductive Agency Scale 17 (RAS-17), composing pregnancy-specific and non-pregnancy-specific agency items among Qatari and non-Qatari women with a normal pregnancy [20], was excluded to achieve the maximum homogeneity of the results. Some scales such as the Survey-Based Womens Empowerment (SWPER) Index and Composite Womens Empowerment Index (CWEI) have been developed to measure women empowerment [21, 22]; however, they did not include in this review because they were not applicable in sexual or reproductive health.

A detailed description of the included scales is shown in Table 1. The results revealed that included articles did not represent diverse geographical areas. The majority of studies (8/15) were conducted in the United States [5,6,7,8, 23,24,25,26]. Two were done in Nepal [12, 27], one in Spain [28], and the rest of the studies (4/15) were carried out in African countries [13, 29,30,31]. The sample size varied from 235 to 4674 in primary studies and 111,368 in one study using the Demographic and Health Surveys (DHS). The age of participants ranged between 16 and 71. The items of each scale ranged from 8 to 23. The target population in studies were as following: three studies (3/15) included adolescents and young adults (1524years) [11, 29, 30], three (3/15) were carried out on young women aged 1629 [7, 8, 25]; one conducted in young women 2035years [12]; six studies (6/15) aimed to assess women in reproductive age defined as those aged 15 to 49years [5, 6, 13, 26, 27, 31]. Two studies extended the age group of participants beyond 45years; in one study, women at the ages of 15 to 60 [24]; and in another, women ages 18 to 71 were included [32].

The most common domains of women empowerment in reproductive health that had been measured were: freedom from coercion, decision-making, communication with the partner, choice, control, autonomy, and ability to negotiate. Kabeers framework of empowerment was applied as the empowerment framework in two studies (2/15) [11, 31]; The theory of gender and power developed by Connell in four studies (4/15) [6, 24, 29, 30]; and Sex scripts (gender-stereotypical expectations to engage in sexual behavior) was used in two studies (2/15) [7, 8]. Moreover, the Reproductive empowerment framework developed by Edmeades et al. (2018) and General conceptualization of assertiveness based on human rights to autonomy, each one was used in one study [12]. The World Banks Empowerment Framework and The sexual and health empowerment framework developed by the authors were used in a study conducted by Moreau et al. [13]; whereas the rest of the studies did not apply any specific empowerment framework.

Of the included studies, seven applied either literature review, or expert panels, or empirical method to develop the item pool (Table 2). Adequate internal consistency defined as the alpha>0.7 was reported in nine studies (9/15). However, in four studies, poor internal consistency (<0.70) was seen. Two studies also did not report internal consistency. Most of the studies but three lack reporting testretest reliability. Nine studies proved content validity. Six criteria were applied to score scales by which nine of fifteen articles were rated as medium quality, two rated as poor quality, and four rated as high quality (Table 3).

Sexual and Reproductive Empowerment Scale is a 23-item questionnaire developed and validated by Upadhyay et al. (2020) and aimed to assess the latent construct of sexual and reproductive empowerment among a national sample of American males and females adolescents and young adults (AYAs) aged 1524years. This scale contains the following domains: comfort talking with a partner (three questions); choice of partners, marriage, and children (three questions); parental support (4 questions); sexual safety (4 questions); self-love (4 questions); the sense of future (2 questions); and sexual pleasure (3 questions). The total score could range from 0 to 92. The items can be self-administered, and on average, AYAs could answer all items in less than 2min. The baseline results demonstrated that sexual and reproductive empowerment was associated with access to sexual and reproductive health services and information, and also at 3-month follow-up was moderately associated with the use of desired contraceptive methods. In contrast to most reproductive empowerment measures, this scale can also be used among men and boys [11].

As a multi-dimensional scale, Reproductive Autonomy Scale (RAS) was developed and validated in the USA to measure reproductive autonomy among women. This scale is comprised of 14 items and three subscales. Reproductive autonomy was defined as womens power to decide about and exercise control on issues related to using contraception, pregnancy, and childbearing. The participants were selected from the family planning and abortion facilities in the United States. Three subscales of the scales were freedom from coercion (five questions), communication (five questions), and decision-making (four questions). The study found a reverse association between freedom from coercion and communication subscales with unprotected sex [24].

Hinson et al. (2019) developed and validated the reproductive decision-making agency scale among Nepalese women aged 1549. The 17-item scale attempts to measure womens decision-making over reproductive behaviors in three domains, including womens agency in using family planning methods, agency in choosing the method of family planning, and agency in choosing the time of getting pregnant. In this study, women whose husbands or other relatives rather than themselves mainly made decisions on reproductive behaviors were considered the lowest agency. In contrast, women reporting sole or joint decision makingwere categorized as the medium and high agency, respectively. The scales scores varied between three and nine, the higher scores representing the higher agency. This scale can be applied to assess a range of reproductive outcomes, particularly those related to reproductive control.

WGE-SRH was developed by Moreau, Karp, et al. (2020) in three African countries, Ethiopia, Uganda, and Nigeria, to provide a cross-cultural scale. This 21-items scale attempts to assess the existence of choice and exercise of choice across the three domains related to sex, using contraception, and pregnancy. Participants agreement or disagreement with each item scored from 1 to 10. The results showed that women who indicated higher scores on the contraceptive choice subscale are more likely to use contraception. Moreover, higher scores on the sexual exercise scale were associated with a higher possibility of volitional sex [13].

This 5-item measure was derived from the Reproductive Coercion Scale (RCS) by McCauley et al. (2017). The scale was validated in two longitudinal randomized controlled trials conducted on young English- or Spanish-speaking women aged 1629 in the USA. These five questions constructed two subscales: pregnancy coercion (three items) and condom manipulation (two items). Items include dichotomous (yes/no) answers. The short form of scale was useful in recognizing women who endorse low levels of reproduction coercion. This scale is particularly sensitive to identifying women who experience less common forms and multiple forms of reproduction coercion. Furthermore, this scale would provide a rapid assessment of reproductive coercion in clinics.

SAS was developed to measure womens understanding over the three subscales of assertiveness regarding initiation of sex, refusal of sex, and prevention of sexually transmitted disease/pregnancy (STD-P) with a regular partner. It comprises 18 items rated on a 5-point response format with anchors of 0 (Never) and 4 (Always). The higher scores on the scale, the higher sexual assertiveness is predicted. The SAS was developed and validated in a sample of young American women ages 1629. After 6 and 12months intervals, testretest reliabilities were assessed [5].

Antos-Iglesias and Carlos Sierra (2010) adapted the Hurlbert Index of Sexual Assertiveness (Hurlbert, 1991) among the Spanish community. The psychometric analysis was conducted among 400 Spanish men and 453 women who had a partner for at least six months. The original scale was composed of 25 items, ranging from 1 (Never) to 5 (Always). The total scores were between 0 to 100. The higher scores represent the higher sexual assertiveness. The exploratory and confirmatory factor analyses identified a 19-item structure with two correlated factors (Initiation and No shyness/Refusal). Six items from the original version were eliminated. Finally, the Spanish version showed satisfactory psychometric characteristics [32].

SAQ was derived from the Sexual Assertiveness Scale (Morokoff and colleagues, 1997) by Loshek and Terrell (2014) to provide a scale that does not include the condom insistence. The underlying hypothesis was although the sexual assertiveness scale encompasses condom insistence, it might not be administered to women at all life stages or in various kinds of relationships. The final scale comprises 18 items and three subscales, including the ability to initiate and communicate across desired sex, the ability to refuse unwanted sex, and the ability to talk about sexual history and risk. Response choices included a 7-point scale ranging from 1 (strongly disagree) to 7 (strongly agree). The results demonstrate satisfactory psychometric properties [26].

This 19-items scale aimed to measure gender-stereotypical expectations engaging in sexual behaviors. This study hypothesized that sexual pressure is associated with HIV sexual risk behavior. Scale composed of five factors: Condom Fear, Sexual Coercion, Womens Sex Role, Men Expect Sex, and Show Trust. Higher sexual pressure was identified through a higher score. The SPS can be used to assess to what extent adherence to gender-stereotypical expectations may limit womens sexual choices and lead to adverse consequences, such as being less assertive in communicating their desire to reduce risk and being more likely to be engaged in sex with men who are at the higher risk of HIV [7].

Jones and Gulick (2009) revised the sexual pressure scale (Jones, 2006) to improve its reliability. The study was carried out on a sample of young adult urban women. The reliability and confirmatory factor analysis using structural equation modeling resulted in 18 items with higher reliability than the original scale. After eliminating the Condom Fear factor, a 4-factor model encompassing Show trust, Womens sex role, Men expect sex, and Sexual coercion was remained [8].

This measure was designed by Pulerwitz et al. (2000) to address interpersonal power in sexual decision-making. SRPS consists of 23 items and two subscales, Relationship Control (RC) and Decision-Making Dominance (DM). RC subscale encompasses fifteen,and DM is composed of eight questions. The totalscore was ranged from 8 to 24. Lower scores on SRPS were associated with higher physical violence and lower consistent use of a condom [6].

This scale was derived from the Relationship Control subscale of the SRPS and then validated among AGYW who were at the risk of HIV in Kenya. The original subscale consisted of 15 items. A modified scale was extracted after removing three items related to condom use, resulting in 12 items in total. Participants were asked to express to what extent they agree or disagree with each item on a 4-point Likert scale. The results showed that AGYW with higher relationship power were less likely to experience sexual violence and more likely to use a condom and have knowledge of partners HIV status [29].

SRP equity is a South African adaptation of the Sexual Relationship Power, originally developed by Pulerwitz et al. in 2000 [6]. Over the community-based cohorts, 235 young men and women aged 1624years completed this questionnaire. Follow-up study performed six months later. The original SRPS consists of 13 questions. Participants answered on a 4-point Likert scale for each item, ranging from (strongly agree to strongly disagree). Higher scores representing greater equity in sexual relationship power. Finally, a 8-item scale for women and a 9-item scale for men were constructed. SRP equity was associated with higher education and no recent partner violence [30].

This scale was developed by Bhandari et al. (2014) to provide a validated scale for measuring Nepalese womens autonomy as one of the predictors of using maternal health care services. The 23 items were answered on a 3-point scale anchored with zero (not necessary), one (useful not essential), and two (essential). Three subscales, including decision-making autonomy, financial autonomy, and freedom of movement, constitute the scale. The Autonomy Measurement Scale showed appropriate psychometric characteristics and introduced a valid and standard scale for assessing womens autonomy in developing countries [27].

Using Demographic and Health Surveys (DHS) from nineteen countries in four African regions, a scale composed of 26 indicators was developed to assess different dimensions of women empowerment, including economic, socio-cultural, education, and health. Access to healthcare composes distance, money, and permission. For instance, items such as: whether women have the access or financial constraints to make beneficial health choices were included. If women reported difficulties accessing healthcare services, they were assigned a 0 score; otherwise, women were scored 1. This scale provided region-specific indicators of women empowerment in Sub-Saharan Africa [31].

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