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Gambling Gods Giveth Then Taketh Right Back In Gonzaga-TCU – OutKick

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The end of TCU Horned Frogs vs. Gonzaga Bulldogs Sunday in the Round of 32 in the 2023 NCAA Tournament was like a gambling speedball. Regardless of which you side you bet, it was outrageous.

Gonzaga beat TCU 83-81 and the Horned Frogs covered as +4.5 underdogs. But how TCU cashed was bonkers. Just like the rest of this ridiculous tournament.

I mean, do you believe this s***? Gonzaga was anywhere from -4 to -4.5 favorites pregame depending on when you bet it. I gave out Gonzaga as -4 favorites earlier Sunday afternoon and it felt good at the end of the game.

Ill let you be the judge. TCU led 38-33 at the end of the 1st half but the Bulldogs took control in the 2nd half. Gonzagas biggest lead was 9 with 3:28 remaining.

Gonzaga got a key stop and C Drew Timme defensive rebound up 79-73 with :37 remaining before Timme was fouled. The Bulldogs were in the double bonus so Timme was on the line for two.

Timme missed the 1st and made the 2nd to give Gonzaga a 80-73 lead with 0:33 left on the clock. As a Gonzaga -4 bettor, I was pumped. It got even better when the Bulldogs got another stop and defensive rebound in TCUs next possession.

From here the nonsense begins. Gonzaga SF Julian Strawther craps his pants while inbounding the ball. Strawther BOUNCE passes it to TCUs Mike Miles Jr. and then fouls him at the rim to send Miles to the foul line.

Of course, Miles made both to bring the Horned Frogs deficit to 80-75. Then Gonzaga beat TCUs full-court press and SG Hunter Sallis got a breakaway dunk with :09 remaining to give Zaga a 82-75 lead.

Gonzaga -4/-4.5 looks good, right? Ehhh. No. Its never that easy in this racket. TCU charged down the court and banged a 3 to make the game 82-78.

The Bulldogs got fouled after inbounding the ball with less than :01 left to play. For a moment, I got excited. Gonzaga -4 was a freeroll with .07 seconds remaining and a Bulldog shooting two free throws. There is no way TCU covers.

It hurts to type out what happened and you already saw it. For the record, I hate TCU. Those clowns kicked me in the nuts in the College Football Playoff title game and then slapped me in the mouth Sunday.

This was the perfect ending for me in the 1st weekend of the NCAA Tournament. Most of my March Madness futures got nuked and I pretty much lit money on fire this weekend. Im done gambling. Until the Sweet 16.

Listen to the OutKick Bets with Geoff Clark podcast HERE.

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Gambling Gods Giveth Then Taketh Right Back In Gonzaga-TCU - OutKick

‘Even more addictive now’: Malverne man’s gambling problem made worse by legalized sports betting – Newsday

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Gambling nearly destroyed Joe Ruscillos life.By the time he was 20, he says, he owed bookies at least $100,000.

The Malverne native was a star in high school starting quarterback of the varsity football team at Valley Stream North High School his junior and senior years a decade ago, and a member of the varsity basketball and baseball teams.

His SAT scores were good enough to have SUNY Maritime College recruit him to play football, he said.

But Ruscillos downfall began when he discovered gambling. It started at 16 with small bets placed with bookies on games in just about every sport tennis was a favorite. The wagers,made illegally,quickly escalated into the thousands.

Now 26,Ruscillo said he hit rock bottom last year with the advent of legalized online sports betting in New York State.Over the past decade, he figures he wagered between $2 million and $3 million and lost between $200,000 and $300,000 before he began pulling his life back together with the help of his family and girlfriend.

Your first bet was $20 at 16, then it turns into 50, then it turns into 100. And you lose a couple bets in a row and you get yourself in a hole and things just happen, he said.

All of a sudden youre in thousands of dollars of debtto local bookies that you cant pay back. Youre in debtwith your friends that you cant pay back, he said. Its a dangerous road.

I was already addicted and then it made it a lot easier to get a bank account, put some money in it, and the deposit is right there in two seconds.

He owed so much, bookiesput him on payment plans.

As the debts mounted, he nearly lost his friends and family. He leaned on them for loans. When he didnt pay them back, tensions grew.

More than once his parents banished him from their home, forcing him to move in with his grandparents. He often did not have enough money to buy food or gas.

Hes a great kid with a bad problem, said his mother, Jennifer Ruscillo.

Besides the loans, he gambled with money from his jobs working in sanitation, his familys car glass businessand waiting tables.

The hard-earned money that you made that week you can lose in literally a minute, he said. Its scary.

His mother said she has taken him to everyone she could think of to get help doctors, psychologists, psychiatrists, Gamblers Anonymous meetings but none were able to cure him.

The beginningof legalized online sports betting in January 2022 in New York sent him over the edge, Joe Ruscillo said.

I was already addicted and then it made it a lot easier to get a bank account, put some money in it, and the deposit is right there in two seconds, he said.

Ruscillo said the ubiquitous ads especially on iPhones made it almost impossible for him to resist.

Me, knowing so much about it, even at the time knowing how bad it is and knowing how detrimental it is to your life, they still got me, he said of the ads.

He figures he lost between $40,000 and $50,000 within the first two months of online sports betting becoming legal in New York.

recommended readingFueled by legal sports betting, gambling addiction rises on Long Island, experts say

His mother said she became terrified when a sports game would appear on the TV at their home.

I cringe when sports come on, she said. Its not the love of sports anymore. Its, Oh my God, is he going to place a bet? How much are we going to lose this time?

The online sports betting made Joe Ruscillo realize he could not go on this way. He came clean to his family and girlfriend, and said he needed more help.They came up with a radical solution: He threw away his iPhone and replaced it with an old-fashioned flip phone one he cant place bets on.

He also hands over every paycheck to his mother so he doesnt have access to money to gamble.

The strategy is working. He has paid off almost all his debts, and is saving money in the bank. He and his girlfriend are looking to buy a house or a condo.

Jennifer Ruscillo, the mother of Joe Ruscillo, cringes when sports come on. Its not the love of sports anymore. Its, Oh my God, is he going to place a bet? How much are we going to lose this time? she said. Credit: Morgan Campbell

Im in the best place Ive ever been in my life, he said. Ive got a bunch of money saved. I dont gamble. And all my friends who are my real friends are still around.

His advice to young people is to stay away from gambling.

You go to the Gamblers Anonymous and there are 60-, 70-year-old men in there that are still battling the addiction today, and they did not even have the apps, he said. If it was addictive back then, its even more addictive now.

His mother is even more severe in her warnings. Gambling, she said, should be banned. It should not even exist.

With Jamie Stuart

Bart Jones has covered religion, immigration and major breaking news at Newsday since 2000. A former foreign correspondent for The Associated Press in Venezuela, he is the author of HUGO! The Hugo Chavez Story from Mud Hut to Perpetual Revolution.

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'Even more addictive now': Malverne man's gambling problem made worse by legalized sports betting - Newsday

The Benefits of Using Stablecoins for Crypto Gambling – GLYFE Nation

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The use of stablecoins in the casino industry has increased recently. Stablecoins have gained popularity in the gambling industry due to their stability and the advantages they offer over traditional payment methods.

One might ask why anyone would use a stablecoin for gambling purposes if the primary value of cryptocurrencies lies in their volatility. However, regarding crypto casino games, stablecoins offer unique benefits, making them a preferred payment method for many players.

Stablecoins are a special class of cryptocurrencies engineered to maintain a consistent value relative to a specific asset, such as fiat currencies or commodities such as gold.

They achieve this stability by anchoring their value to the price of the designated asset, ensuring that the stablecoins value remains comparatively steady and eliminating the volatility typically associated with other cryptocurrencies.

Stablecoins can maintain a stable value and achieve this through reserved assets that act as collateral for each stablecoin. Typically, stablecoins have a 1:1 ratio, meaning that one stablecoin equals one unit of the reserved asset.

However, there are different methods for achieving stability; for instance, centralized fiat-backed stablecoins rely on an organization or company to regulate the issuance and burning of new coins based on demand. Tether (USDT) is an example of this, where a private custodian monitors the currency and holds a reserve of equivalent collateral.

In contrast, decentralized crypto-backed stablecoins such as Dai (DAI) use smart contracts on the Ethereum blockchain to manage and oversee the collateral without relying on a governing body.

Various types of stablecoins exist, each using its own mechanism to preserve a stable value. These include:

Overall, stablecoins have become increasingly popular in recent years, particularly in cryptocurrency trading and decentralized finance (DeFi) applications. You can use them as a means of payment, a store of value, or collateral for other financial instruments.

Stablecoins have emerged as a game-changing solution in the world of crypto gambling, offering numerous benefits over traditional cryptocurrencies.

By harnessing the advantages of stablecoins, both players and operators can experience a more streamlined, secure, and user-friendly gambling environment.

Enhanced Price Stability

By design, stablecoins maintain a stable value, eliminating the extreme price fluctuations often associated with traditional cryptocurrencies. This stability enables gamblers to play without worrying about sudden changes in the value of their digital assets.

The inherent stability of stablecoins allows players to manage their bankroll better and anticipate potential returns, creating a more predictable gaming experience.

Improved Transaction Efficiency

Stablecoins facilitate quick and efficient transactions, allowing players to deposit and withdraw funds almost instantly, with minimal delays and waiting times.

By using blockchain technology, stablecoin transactions often incur lower fees than traditional payment methods, reducing the overall cost of gambling activities for both operators and players.

Increased Accessibility and Financial Inclusion

Stablecoins enable seamless cross-border transactions, allowing users worldwide to participate in crypto gambling without facing restrictions due to local regulations or currency conversion issues.

With no need for a traditional bank account, stablecoins provide an accessible alternative for the unbanked or underbanked populations, allowing them to engage in online gambling activities.

Enhanced Privacy and Security

Stablecoin transactions on blockchain networks provide a higher degree of privacy, allowing users to maintain their anonymity while participating in online gambling activities.

Blockchain technology ensures the security of stablecoin transactions, reducing the risk of fraud, hacking, or unauthorized access to users funds.

Regulatory Compliance and Transparency

As stablecoins are often pegged to traditional assets, such as fiat currencies, they are more likely to comply with existing financial regulations, promoting a safer and more regulated environment for crypto gambling.

The transparent nature of blockchain technology enables the auditing of stablecoin transactions, ensuring fair play and fostering trust among users and operators.

By leveraging these benefits, stablecoins have the potential to significantly improve the online gambling experience for both operators and players alike.

Stablecoins have become a fundamental part of the cryptocurrency ecosystem, with Tether occupying the third spot after Bitcoin and Ethereum. However, despite being considered the gold standard of digital currency, stablecoins are not immune to issues; for example, its private reserves have drawn scrutiny from the US government.

Therefore, many centralized stablecoins focus on transparency and regulation to avoid government scrutiny. The NYDFS regulates BUSDs monthly audits, and TUSD is audited by the private firm Cohen & Company. Other companies, such as Tether, publish their records on their websites and update them in real-time to prove transparency.

Moreover, the future of stablecoins appears to be moving towards government regulation to ensure consumer protection. Given their widespread use and popularity, the US Securities and Exchange Commission (SEC) and Federal Reserve have called for creating a regulatory framework for stablecoins.

As a result, users can feel more confident that their funds are safe and secure with regulated parties.

Stablecoins can potentially revolutionize the crypto-gambling landscape by addressing the volatility concerns of traditional cryptocurrencies. With their enhanced stability, improved transaction efficiency, increased accessibility, financial inclusion, and heightened privacy, stablecoins provide a compelling alternative for online gambling enthusiasts.

By embracing stablecoins, the online gambling industry can create a more predictable, secure, and inclusive environment that caters to the diverse needs of players and operators alike. As stablecoins continue to gain traction, they are poised to become an integral part of the ever-evolving world of crypto gambling.

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The Benefits of Using Stablecoins for Crypto Gambling - GLYFE Nation

FanDuel Parent Flutter Is Gaining Traction in the U.S. Gambling. Bet on the Stock. – Barron’s

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Shares of FanDuel parent Flutter Entertainment are beginning to find momentum after the company started exploring a U.S. listingbut its not too late to bet on the stock.

Theres no doubting FanDuels strength in the U.S. sports betting market. It reached a 50% share of the online sportsbook market in the fourth quarter, Flutter says, citing data from the 17 states the brand operates in.

Flutters full-year earnings reported earlier this month only served to accentuate that strength, flagging a record Super Bowl, adding 1.2 million new customers in the first two months of this year, making progress on an additional New York listing, and remaining on track for its U.S. business to turn profitable in 2023.

Its a significant, but very achievable, milestone. The segment generated positive Ebitda in the second and fourth quarters, when excluding investment in state launches in Maryland and Ohio.

Despite that, the stock (ticker: FLTR.United Kingdom) initially fell after earnings. The move was indicative of a longstanding issueinvestors underplaying the U.S. growth opportunityon this occasion focusing on weakness in Australia.

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The U.K. market may also be a factor. Citi analysts said earlier this month that the U.K. stock market currently trades at a record 40% discount to the U.S.

In addition to FanDuel, the sports betting and gaming company owns a number of brands, including Paddy Power, PokerStars, Betfair, and SportsBet, operating in more than 100 countries.

Flutter stock has climbed 24% so far this year, and has moved higher since its postearnings dip. Perhaps investors are starting to wake up to the bigger picture.

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Susquehanna analyst Joe Stauff says a New York listing, which he assumes will happen in the fourth quarter of 2023, would be a value-creating event, which would reduce the 20% conglomerate discount it currently applies to the value of Flutters U.S. business. He has a Buy rating on the stock and a price target of 163 ($197), implying a 21% upside to its recent price of 135.

For context, the U.S. market size for Flutter over the next two years will be as large as the combined nine largest countries it currently competes in today, which includes the U.K., Australia, and Brazil, Stauff noted.

Analysts covering the stock, of which 80% rate it as a Buy, expect strong growth over the next few years. Flutter is expected to post revenue of 9.1 billion this year, and 10.2 billion in 2024, up from 7.7 billion last year. Earnings per share are also seen growing to 3.80 in 2023 and 5.69 the following year, up from 1.89 in 2022.

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With our combined U.S. business on track to deliver a positive Ebitda for the full year 2023 for the first time, the Group is currently at an earnings transformation point and we look forward to delivering future growth and progressing further against Flutters strategic priorities in the coming year, Flutter CEO Peter Jackson said in a statement earlier this month.

There are other reasons to be positive. Flutters U.K. and international performance held up well in the fourth quarter, in the face of a challenging macroeconomic environment.

The stock also isnt too expensive, trading at 24.7 times estimated 2024 earnings, lower than an average of around 34 times among a basket of competitors, according to FactSet data.

Stricter-than-anticipated U.K. gambling reforms, expected to be put forward later this year, present a risk to the stock but theres many more reasons to consider a bet on the shares continuing higher.

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FanDuel Parent Flutter Is Gaining Traction in the U.S. Gambling. Bet on the Stock. - Barron's

Online Gambling And Its Advantages To Players – Salon Priv Magazine

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Online gambling has attracted a lot of players because of its advantages and benefits that casino players find very hard to say no to.

Online gambling refers to the act of wagering money or something of value on an uncertain outcome of an event or game, using the internet as the medium of communication. It involves playing games of chance or skill, betting on sports events, or participating in lotteries, bingo, poker, or casino games via electronic devices such as computers, smartphones, or tablets.

Online gambling can take place through websites, apps, or social media platforms and can involve real money or virtual currencies. You will find more information at onlinecasino-thai that can help you understand online casino gambling better.

One of the reasons why people gamble online is because of the advantages they get from it. These benefits cannot be enjoyed when playing at land-based casinos.

Convenience and accessibility are two significant advantages of online gambling that attract a growing number of players. Here are some reasons why:

Online gambling offers a vast variety of games and betting options, including:

Online gambling offers increased privacy compared to traditional gambling methods. Here are some reasons why:

While increased privacy can be a benefit of online gambling, it is essential to remember that it can also contribute to problem gambling behaviours. Players may be more likely to gamble beyond their means or in secret, which can lead to negative consequences. Therefore, it is essential to practice responsible gambling habits and seek help if needed.

Online gambling sites offer various bonuses and promotions to entice new players and keep their existing players interested. Here are some examples of bonuses and promotions in online gambling:

While bonuses and promotions can be enticing, it is important to read and understand the terms and conditions carefully before accepting them. Players should understand the wagering requirements, expiration dates, and any other restrictions that may apply to the bonus or promotion.

Its also essential to gamble responsibly, not letting bonuses and promotions encourage excessive or problematic gambling behaviour.

In conclusion, online gambling offers a range of benefits, including convenience, accessibility, variety, increased privacy, and bonuses and promotions. You will find all the information you might need at onlinecasino-thai. However, it is essential to approach online gambling responsibly and within ones means to avoid negative consequences.

Players should also ensure that they gamble on reputable and licensed online gambling sites to protect their personal and financial information. It is also imperative to be aware of the potential risks of online gambling, such as addiction and financial loss, and seek help if needed. Online gambling can be a fun and entertaining pastime as long as it is approached with caution and responsible gambling practices.

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Online Gambling And Its Advantages To Players - Salon Priv Magazine

Toney gets England call-up as potential gambling ban looms – The Associated Press

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With a possible suspension looming for apparently breaching multiple gambling rules, Ivan Toney was called up by England for its upcoming European Championship qualifiers as a reward for being the third-leading scorer in the Premier League.

It is the second time the Brentford striker has been summoned by England. The first was ahead of Nations League qualifiers in September but he didnt get onto the field and failed to make the squad for the World Cup a few weeks later.

Toney has scored 16 league goals for Brentford this season only Erling Haaland and England striker Harry Kane have more but his future is clouded after being charged with a total of 262 breaches of the Football Associations gambling laws, dating back to 2017.

Sections of the British media reported this month that Toney has admitted to the majority of the breaches and was facing a lengthy spell out of the game. That led to Toney criticizing the FA about the process behind his impending disciplinary hearing and over what he perceives to be potential lapses of confidentiality as he prepares to argue his case.

The issue hasnt stopped England coach Gareth Southgate from selecting Toney as one of six forwards in a 25-man squad ahead of Euro 2024 qualifiers against Italy and Ukraine.

The fact is, he is available for his club, Southgate said about the selection of Toney. There hasnt been a trial as yet or any judgment so I dont know on what basis we wouldnt pick him.

They are Englands first games since the national team lost to France the World Cup quarterfinals in December.

___

More AP soccer: https://apnews.com/hub/soccer and https://twitter.com/AP_Sports

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Toney gets England call-up as potential gambling ban looms - The Associated Press

Applications of nanotechnology – Wikipedia

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Potential applications of carbon nanotubesEdit

Nanotubes can help with cancer treatment. They have been shown to be effective tumor killers in those with kidney or breast cancer.[4][5] Multi-walled nanotubes are injected into a tumor and treated with a special type of laser that generates near-infrared radiation for around half a minute. These nanotubes vibrate in response to the laser, and heat is generated. When the tumor has been heated enough, the tumor cells begin to die. Processes like this one have been able to shrink kidney tumors by up to four-fifths.[4]

Ultrablack materials, made up of forests of carbon nanotubes, are important in space, where there is more light than is convenient to work with. Ultrablack material can be applied to camera and telescope systems to decrease the amount of light and allow for more detailed images to be captured.[6]

Nanotubes show promise in treating cardiovascular disease. They could play an important role in blood vessel cleanup. Theoretically, nanotubes with SHP1i molecules attached to them would signal macrophages to clean up plaque in blood vessels without destroying any healthy tissue. Researchers have tested this type of modified nanotube in mice with high amounts of plaque buildup; the mice that received the nanotube treatment showed statistically significant reductions in plaque buildup compared to the mice in the placebo group.[7] Further research is needed for this treatment to be given to humans.

Nanotubes may be used in body armor for future soldiers. This type of armor would be very strong and highly effective at shielding soldiers bodies from projectiles and electromagnetic radiation. It is also possible that the nanotubes in the armor could play a role in keeping an eye on soldiers conditions.[8]

Nanotechnology's ability to observe and control the material world at a nanoscopic level can offer great potential for construction development. Nanotechnology can help improve the strength and durability of construction materials, including cement, steel, wood, and glass.[9]

By applying nanotechnology, materials can gain a range of new properties. The discovery of a highly ordered crystal nanostructure of amorphous C-S-H gel and the application of photocatalyst and coating technology result in a new generation of materials with properties like water resistance, self-cleaning property, wear resistance, and corrosion protection.[10] Among the new nanoengineered polymers, there are highly efficient superplasticizers for concrete and high-strength fibers with exceptional energy absorbing capacity.[10]

Experts believe that nanotechnology remains in its exploration stage and has potential in improving conventional materials such as steel.[10] Understanding the composite nanostructures of such materials and exploring nanomaterials' different applications may lead to the development of new materials with expanded properties, such as electrical conductivity as well as temperature-, moisture- and stress-sensing abilities.[10]

Due to the complexity of the equipment, nanomaterials have high cost compared to conventional materials, meaning they are not likely to feature high-volume building materials.[11] In special cases, nanotechnology can help reduce costs for complicated problems. But in most cases, the traditional method for construction remains more cost-efficient.[11] With the improvement of manufacturing technologies, the costs of applying nanotechnology into construction have been decreasing over time and are expected to decrease more.[11]

Nanoelectronics refers to the application of nanotechnology on electronic components. Nanoelectronics aims to improve the performance of electronic devices on displays and power consumption while shrinking them.[3] Therefore, nanoelectronics can help reach the goal set up in Moore's law, which predicts the continued trend of scaling down in the size of integrated circuits.

Nanoelectronics is a multidisciplinary area composed of quantum physics, device analysis, system integration, and circuit analysis.[12] Since de Broglie wavelength in the semiconductors may be on the order of 100nm, the quantum effect at this length scale becomes essential.[12] The different device physics and novel quantum effects of electrons can lead to exciting applications.[12]

The terms nanobiotechnology and bionanotechnology refer to the combination of ideas, techniques, and sciences of biology and nanotechnology. More specifically, nanobiotechnology refers to the application of nanoscale objects for biotechnology while bionanotechnology refers to the use of biological components in nanotechnology.[1]

The most prominent intersection of nanotechnology and biology is in the field of nanomedicine, where the use of nanoparticles and nanodevices has many clinical applications in delivering therapeutic drugs, monitoring health conditions, and diagnosing diseases.[13] Being that much of the biological processes in the human body occur at the cellular level, the small size of nanomaterials allows for them to be used as tools that can easily circulate within the body and directly interact with intercellular and even intracellular environments. In addition, nanomaterials can have physiochemical properties that differ from their bulk form due to their size,[14] allowing for varying chemical reactivities and diffusion effects that can be studied and changed for diversified applications.

A common application of nanomedicine is in therapeutic drug delivery, where nanoparticles containing drugs for therapeutic treatment of disease are introduced into the body and act as vessels that deliver the drugs to the targeted area. The nanoparticle vessels, which can be made of organic or synthetic components, can further be functionalized by adjusting their size, shape, surface charge, and surface attachments (proteins, coatings, polymers, etc.).[15] The opportunity for functionalizing nanoparticles in such ways is especially beneficial when targeting areas of the body that have certain physiochemical properties that prevent the intended drug from reaching the targeted area alone; for example, some nanoparticles are able to bypass the Blood Brain Barrier to deliver therapeutic drugs to the brain.[16] Nanoparticles have recently been used in cancer therapy treatments and vaccines.[17][18]

In vivo imaging is also a key part in nanomedicine, as nanoparticles can be used as contrast agents for common imaging techniques such as computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET).[13] The ability for nanoparticles to localize and circulate in specific cells, tissues, or organs through their design can provide high contrast that results in higher sensitivity imaging, and thus can be applicable in studying pharmacokinetics or visual disease diagnosis.[13][15]

The energy applications of nanotechnology relates to using the small size of nanoparticles to store energy more efficiently. This promotes the use of renewable energy through green nanotechnology by generating, storing, and using energy without emitting harmful greenhouse gases such as carbon dioxide.

Nanoparticles used in solar cells are increasing the amount of energy absorbed from sunlight.[19] Solar cells are currently created from layers of silicon that absorb sunlight and convert it to usable electricity.[20] Using noble metals such as gold coated on top of silicon, researchers have found that they are able to transform energy more efficiently into electrical current.[20] Much of the energy that is loss during this transformation is due to heat, however by using nanoparticles there is less heat emitted thus producing more electricity.[20]

Nanotechnology is enabling the use of hydrogen energy at a much higher capacity.[21] Hydrogen fuel cells, while they are not an energy source themselves, allow for storing energy from sunlight and other renewable sources in an environmentally-friendly fashion without any CO2 emissions.[21] Some of the main drawbacks of traditional hydrogen fuel cells are that they are expensive and not durable enough for commercial uses.[22] However, by using nanoparticles, both the durability and price over time improve significantly.[22] Furthermore, conventional fuel cells are too large to be stored in volume, but researchers have discovered that nanoblades can store greater volumes of hydrogen that can then be saved inside carbon nanotubes for long-term storage.[22]

Nanotechnology is giving rise to nanographene batteries that can store energy more efficiently and weigh less.[23] Lithium-ion batteries have been the primary battery technology in electronics for the last decade, but the current limits in the technology make it difficult to densify batteries due to the potential dangers of heat and explosion.[21] Graphene batteries being tested in experimental electric cars have promised capacities 4 times greater than current batteries with the cost being 77% lower.[23] Additionally, graphene batteries provide stable life cycles of up to 250,000 cycles,[24] which would allow electric vehicles and long-term products a reliable energy source for decades.

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Applications of nanotechnology - Wikipedia

Our Campuses | Temple University Office of Undergraduate Admissions

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Temples other campuses provide unique learning experiences for undergraduate students and are home to many graduate and professional schools and programs. While most undergraduate students dont take classes on these campuses, they are still an integral part of the Temple community.

Located in downtown Philadelphia, just a short subway ride away from Main Campus, Temple University Center City (TUCC) offers an alternative location to take certain courses in conjunction with coursework at Main and Ambler campuses.For example, undergraduate students can study at Main Campus and choose to take one course in Center City. TUCC allows students to complete coursework in a format that meets their professional and personal needs.

Benefits of TUCC include

Explore our Center City campus and view the campus map.

Temple Harrisburg is located across the street from the Pennsylvania State Capitol. Here, we offer

Learn more about our Harrisburg Campus and view a map of campus.

Located in North Philadelphia, Temples Health Sciences Center is home to our medical-related professional schools and colleges. Students in our Bachelor of Science in Nursingprogramtake classes at this campus, and other students can participate in internship and research opportunities here.

Explore our Health Sciences Campus and facilities or view a map of campus.

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Our Campuses | Temple University Office of Undergraduate Admissions

Pharmacogenomics – National Institute of General Medical …

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How is pharmacogenomics affecting medical treatment?

Currently, doctors prescribe drugs based mostly on factors such as a patients age, weight, sex, and liver and kidney function. For a few drugs, researchers have identified gene variants that affect how people respond. In these cases, doctors can select the best medication and dose for each patient.

Additionally, learning how patients respond to medications helps to discern the different forms of their diseases.

For many years, NIH-funded scientists, through the Pharmacogenomics Research Network (PGRN), have studied the effect of genes on medications relevant to a wide range of conditions, including asthma, depression, cancer, and heart disease. The research findings are collected in an online resource called PharmGKB. In addition, the Clinical Pharmacogenetics Implementation Consortium (CPIC) was started as a shared partnership between the PGRN and PharmGKB to help lower the barrier to clinical use of pharmacogenetic tests. CPIC creates, curates, and posts freely available, peer-reviewed, evidence-based, updatable, and detailed gene/drug clinical practice guidelines. Another NIH-funded project, the Clinical Genome Resource, aims to define the clinical relevance of genes and variants for use in precision medicine and research.

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Pharmacogenomics – Genome.gov

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Understanding pharmacogenomics would not be possible without sequencing the genomes of many people and comparing them, and then comparing their response to medicines. But we have also learned that a person's genome sequence is not everything when it comes to medication responses. The human body is a very complicated machine, and the instructions written in our DNA are just part of the process.

There are some cases, as with the breast cancer treatment tamoxifen, where a small study showed that there might be a relationship between someone's response to the medicine and a variant in theCYP2D6gene. However, this finding did not appear to be true in a larger study that involved many more people. That's why at this time, the U.S. Food and Drug Administration (FDA) labeling for tamoxifen does not recommendCYP2D6pharmacogenomic testing, butthe issue is still being reviewedas more research is conducted.

Another gene in the sameCYPfamily, calledCYP2C19, has variations which affect how your body can useclopidogrel(more commonly known as Plavix). This medication is a "blood thinner" which helps prevent blood clots, and thus reduces your risk of strokes or some heart attacks. If yourCYP2C19protein is not working properly due to a mutation in the gene, then you will not be able toprocess clopidogrel, and you need either a different dose or a different medication. As it turns out, these variants inCYP2C19are also more common in those with Asian ancestry. Although testing for variants in this gene is also not routinely recommended, you may wish to speak with your healthcare provider about the test if you are given a prescription for clopidogrel, particularly if you have East Asian family members.

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Pharmacogenomics - Genome.gov

PHARMACOGENOMICS: Driving Personalized Medicine

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Personalized medicine tailors therapies, disease prevention, and health maintenance to the individual, with pharmacogenomics serving as a key tool to improve outcomes and prevent adverse effects. Advances in genomics have transformed pharmacogenetics, traditionally focused on single gene-drug pairs, into pharmacogenomics, encompassing all 'omics' fields, e.g., proteomics, transcriptomics, metabolomics, and metagenomics. This review summarizes basic genomics principles relevant to translation into therapies, assessing pharmacogenomics' central role in converging diverse elements of personalized medicine. We discuss genetic variations in pharmacogenes (drug-metabolizing enzymes, drug transporters, and receptors), their clinical relevance as biomarkers, and the legacy of decades of research in pharmacogenetics. All types of therapies, including proteins, nucleic acids, viruses, cells, genes, and irradiation, can benefit from genomics, expanding the role of pharmacogenomics across medicine. FDA approvals of personalized therapeutics involving biomarkers increase rapidly, demonstrating the growing impact of pharmacogenomics. A beacon for all therapeutic approaches, molecularly targeted cancer therapies highlight trends in drug discovery and clinical applications. To account for human complexity, multi-component biomarker panels encompassing genetic, personal, and environmental factors can guide diagnosis and therapies, increasingly involving artificial intelligence to cope with extreme data complexities. However, clinical application encounters substantial hurdles, such as unknown validity across ethnic groups, underlying bias in health care, and real-world validation. This review will address the underlying science and technologies germane to pharmacogenomics and personalized medicine, integrated with economic, ethical, and regulatory issues - providing insights into the current status and future direction of health care. Significance Statement Personalized medicine aims to optimize health care for the individual patients with use of predictive biomarkers to improve outcomes and prevent adverse effects. Pharmacogenomics drives biomarker discovery and guides the development of targeted therapeutics. This review addresses basic principles and current trends in pharmacogenomics, with large-scale data repositories accelerating medical advances. The impact of pharmacogenomics is discussed, along with hurdles impeding broad clinical implementation, in the context of clinical care, ethics, economics, and regulatory affairs.

Keywords: Genetic polymorphisms; cancer; developmental pharmacology; drug metabolism; drug-drug interactions; gene regulation/transcription; pharmacogenetics/pharmacogenomics; systems pharmacology.

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PHARMACOGENOMICS: Driving Personalized Medicine

There is a backup of our youth in cells that can be reversed: David …

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New Delhi,UPDATED: Mar 18, 2023 15:53 IST

Dr David Sinclair speaking at the India Today Conclave 2023 in Delhi. (Photo: India Today)

By India Today Science Desk: There is a backup of youth in our cells that we have recently learned about that can be made to work, Dr David Sinclair, Professor in the Department of Genetics at Harvard Medical School said. He added that the technology to reverse aging and trigger bio switches is developing faster than we expected.

"The science of aging and reversal has come a long way. It was considered crazy 20 years ago, but today we understand what drives aging and there is a backup of youth in our cells that we have recently learned that can be made to work. Technology is developing faster," Dr Sinclair added.

David Sinclair was speaking at the India Today Conclave 2023 in Delhi. He discussed the science of age and disease reversal as more and more research pours into understanding the process of aging. The 53-year-old genetics professor, who is also an anti-aging researcher, was recently in the news as he claimed his biological age is 10 years younger.

"What we discovered is that there are genes that control how long we live. Some people are born with the best version of those genes who tend to live for 100 years and what we have discovered is how we live our lives, move and consume, sleep, and how relaxed we are modifies another type of system known as epigenomes," Dr. Sinclair said.

Known for his work on understanding why we age and how to slow its effects, Dr. Sinclair said that the good news is that aging is easier to slow and reverse than we thought. The bad news is that the process gives our bodies a shock.

Speaking about the diet he takes to slow the process, the genetics professor said that there is a set of genes that get turned on when there is not enough energy, like low sugar and protein, and they defend the body against the damage that causes the aging process.

"I skip meals at times, but my goal is to not eat a large meal until dinner and then have a healthy vegan meal and little alcohol. I switched completely to planets and my body has responded well, my skin looks better, my memory is better. The three-meal system plus snacks is aging us faster than we need to," Dr. Sinclair said.

Talking about plant-based meals that he switched from meat and alcohol to slow his aging process, Dr. Sinclair said that "The proteins that are in plants have a ratio of amino acids that stimulate longevity genes, and if you eat meat every meal the body does not fight the way plants help it do."

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Sibu Kumar Tripathi

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Mar 18, 2023

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There is a backup of our youth in cells that can be reversed: David ...

Four habits to reduce your biological age | Fortune Well

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Whats the secret to looking and feeling younger? For some, its expensive surgeries. For others, its a change in health and wellness habits. But what does science say?

David Sinclair, a 53-year-old genetics professor and anti-aging researcher who claims his biological age is 10 years younger, swears by four key habits:

While these habits can certainly contribute to a healthy lifestyle overall, experts disagree about their link to longevity. For example, research is mixed on whether intermittent fasting can slow the aging process. But Sinclair, who is also the cofounder of Tally Health, a membership-based longevity platform that includes TallyAge testing, an at-home test to determine your biological age, says his habits have dramatically altered his life span.

My calculated biological age has been going down for the past decade or more to a point where Im predicted to live at least a decade longer than I would have if I hadnt done anything, Sinclair said in a recent interview with Insider. So its never too late.

In addition to a plant-based diet and cutting back on alcohol, Sinclair shared that he drinks one to two matcha teas per day and takes supplements that contain resveratrol, an anti-inflammatory compound most commonly found in red wine. But the jury is out on whether people can reap the same benefits in a pill form.

As soon as I see resveratrol in anybodys supplement stack, they lose all credibility, University of Washington longevity researcher Matt Kaeberlein told Insider. Its been disproven over and over and over in the longevity field, at least.

Sinclair, however, maintains that these habits arent just about living longer, but making the most of healthy years.

Nobody wants to be sick for a decade or have cancer that drags on or be frail, he told Insider. What were really talking about is preventing those things, or squeezing them into the last bit of life.

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Four habits to reduce your biological age | Fortune Well

Neurologists Near Me in Pompano Beach, FL | Healthgrades

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A neurologist specializes in caring for people with diseases and conditions of the brain and nervous system, including the spinal cord, nerves, muscles, and related blood vessels. Neurologists diagnose and treat many diseases, including stroke, Alzheimers disease, headaches,seizures, and brain and spinal cord injuries. Neurologists are also experts in preventing neurological disease and in reducing neurological disability.

A neurologist typically:

Evaluates a patients medical history and educates the patient about brain and nervous system health and disease prevention

Performs physical exams that include evaluating blood pressure, vital signs, and the health of the brain and nervous system

Orders and interprets laboratory and imaging tests and prescribes medications

Diagnoses and treats acute and chronic diseases and conditions that affect the brain and nervous system including multiple sclerosis, Parkinsons disease, andmeningitis

Screens, treats and monitors conditions that increase the risk of serious brain and nervous system conditions, such as ahead injurythat can lead to long-term memory loss and headaches

Performs certain invasive procedures such as nervous system biopsies

Provides direct care for brain and nervous system conditions in the office and in the hospital

Works closely with your primary care doctor and other specialists and members of your healthcare team to provide optimal care

Neurologists may also be known by the following names: brain doctor, brain specialist, and nerve doctor.

There are 108 specialists practicing Neurology in Pompano Beach, FL with an overall average rating of 3.7 stars. There are 41 hospitals near Pompano Beach, FL with affiliated Neurology specialists, including Boca Raton Regional Hospital, Holy Cross Hospital and Broward Health North.

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Neurologists Near Me in Pompano Beach, FL | Healthgrades

What is Biotechnology? Master of Biotechnology

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The biotechnology revolution, fueled by the sequencing of the human genome, will affect every aspect of the way we live, from our environment, to what we eat, to how we diagnose and treat illness. Already, biotechnology has improved the quality of our lives. In the next decade, as the pace of advances in biotechnology accelerate, the scope and volume of biotechnologys effects will be even greater.

What is biotechnology? In its broadest definition, biotechnology is the use of advances in molecular biology for applications in human and animal health, agriculture, environment, and specialty biochemical manufacturing. In the next century, the major driving force for biotechnology will be the strategic use of genomic information. With the completion of the human genome project, the subsequent understanding of what these genes code for and how the products of these genes relate and interact, will completely transform the practice of medicine. It is now possible to translate discoveries in bacteria, yeast, or fruit flies into important therapeutic targets for drug discovery. DNA chip diagnostics, cell and gene therapy, and tissue engineering will emerge over the next ten years as important biotechnology products.

Biotechnology the interdisciplinary frontier between biology, engineering, medicine and plant science is also the scene of exciting scientific and technological developments in many areas of science. Important areas of development include:

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What is Biotechnology? Master of Biotechnology

What is Biotechnology? Definition, Types and Applications | TechTarget

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What is biotechnology?

Biotechnology is the use of biology to develop new products, methods and organisms intended to improve human health and society. Biotechnology, often referred to as biotech, has existed since the beginning of civilization with the domestication of plants, animals and the discovery of fermentation.

Early applications of biotech led to the development of products such as bread and vaccines. However, the discipline has evolved significantly over the last century in ways that manipulate the genetic structures and biomolecular processes of living organisms. The modern practice of biotechnology draws from various disciplines of science and technology, including the following:

This approach has resulted in innovations and breakthroughs in the following areas:

Modern applications of biotechnology work most often through genetic engineering, which is also known as recombinant DNA technology. Genetic engineering works by modifying or interacting with the genetic cell structures. Every cell in an animal or plant contains genes that produce proteins. It's those proteins that determine the characteristics of the organism.

By modifying or interacting with genes, scientists can strengthen the characteristics of an organism or create an entirely new organism. These modified and new organisms may be beneficial to humans, such as crops with higher yields or increased resistance to drought. Genetic engineering also enables the genetic modification and cloning of animals, two controversial developments.

Biotechnology began at least 6,000 years ago with the agricultural revolution. This early era was characterized by exploiting living organisms in their natural forms or modifying their genetic makeup through selective breeding.

Around the same time, humans learned to harness the biological process of fermentation to produce bread, alcohol and cheese. People also began changing the genetic makeup of domesticated plants and animals through selective breeding.

Selective breeding works by breeding parents with desirable characteristics to express or eliminate certain genetic characteristics in their offspring. Over time, species that are selectively bred evolve to be different from their wild ancestors. For instance, during the agricultural revolution, wheat was selectively bred to stay on its stem when harvested instead of falling to the ground like wild wheat. Dogs were selectively bred to be more docile than their wolf ancestors.

However, biotech methods such as selective breeding can take a long time to show changes in species. Biotechnology remained limited to these slow, agricultural methods until the 19th century when biologist Gregor Mendel discovered the basic principles of heredity and genetics.

Also, during that era, scientists Louis Pasteur and Joseph Lister discovered the microbial processes of fermentation. This laid the foundation for biotechnology industries where scientists interact more directly with the molecular and genetic processes of organisms.

Based on the work of these scientists, genetic engineering was developed in 1973. This method is the foundation of modern biotechnology practices and recent advances. It enabled the first direct manipulation of plant and animal genomes, which is the complete set of genes present in a cell.

Over the last 100 hundred years or so, biotechnology emerged with the following discoveries and advancements:

1919. Hungarian scientist Karl Ereky coins the term biotechnology.

1928. Alexander Fleming discovers penicillin, the first true antibiotic.

1943. Oswald Avery proves DNA carries genetic information.

1953. James Watson and Francis Crick discover the double helix structure of DNA.

1960s. Insulin is synthesized to fight diabetes, and vaccines for measles, mumps and rubella are developed.

1969. The first synthesis of an enzyme in vitro, or outside the body, is conducted.

1973. Herbert Boyer and Stanley Cohen develop genetic engineering with the first insertion of DNA from one bacteria into another.

1980s. The first biotech drugs to treat cancer are developed.

1890. The United States Supreme Court rules that a "live human-made microorganism is patentable subject matter," meaning GMOs can be intellectual property.

1982. A biotech-developed form of insulin becomes the first genetically engineered product approved by the U.S. Food and Drug Administration (FDA).

1983. The first genetically modified plant is introduced.

1993. GMOs are introduced into agriculture with the FDA approval of growth hormones that produce more milk in cows.

1997. The first mammal is cloned.

1998. The first draft of the Human Genome Project is created, giving scientists access to over 30,000 human genes and facilitating research on treatment of diseases such as cancer and Alzheimer's.

2010. The first synthetic cell is created.

2013. The first bionic eye is created.

2020. MRNA vaccine and monoclonal antibody technology is used to treat the SARS-CoV-2 virus.

The science of biotechnology is broken down into subdisciplines that are color-coded based on common uses and applications.

The use and commercialization of modern biotechnology often fall into four main fields: environment, medicine, industry and agriculture.

The aim of environmental biotechnology is to develop sustainable environmental practices that reduce pollution and waste. The following are examples of environmental biotech:

Medical biotechnology, also known as biopharma, aims to fight and prevent disease and improve healthcare. Biotechnology and biomedical research are the basis of the modern pharmaceutical industry. Uses include the following:

Industrial biotechnology involves using microorganisms to produce industrial goods. Examples include the following:

Agricultural biotechnology genetically engineers plants and animals to produce more efficient agriculture, increase nutritional value and reduce food insecurity. Some examples of agricultural biotechnology are the following:

Biotechnology production offers a variety of advantages and solutions to critical problems. The main ones are the following:

Biotechnology also comes with disadvantages and misuse. The main disadvantages include the following:

Concerns about biotechnology's disadvantages have led to efforts to enact legislation restricting or banning certain processes or programs, such as human cloning, GMOs and embryonic stem-cell research.

Biotechnology is critical to environmentally sound advancements in agriculture. Learn more about how technology like artificial intelligence (AI) is improving the food industry.

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What is Biotechnology? Definition, Types and Applications | TechTarget