CU to showcase 75 years of innovation and impact at the 38th … – University of Colorado Boulder

Representatives from across the university, including LASP, CU Boulders AeroSpace Ventures initiative, and the College of Engineering and Applied Science at the University of Colorado Colorado Springs (UCCS), are jointly hosting an exhibit booth at this years Space Symposium. Together, they will highlight CUs prominence in aerospace engineering and climate and space-weather research, as well as the crucial role the university plays in developing Colorados aerospace workforce.

This coordinated presence at the Space Symposium is a great example of how leaders and units from across the university system collaborate to highlight CUs extensive aerospace expertise and the many resources our campuses have to offer, said Chris Muldrow, the Smead Director and Department Chief of Staff in the Ann and H.J. Smead Department of Aerospace Engineering Sciences. We are a world leader in aerospace, and our impact is multiplied when we bring the best of CU aerospace to the space ecosystem.

The College of Engineering and Applied Science at UCCS produces highly qualified undergraduate and graduate students with solid technical backgrounds plus crucial experiential learning. The colleges new Bachelor of Science degree in Aerospace Engineering, which launched this fall with a full cohort of students, will leverage the existing expertise in the Department of Mechanical and Aerospace Engineering. This summer, to stand up the program, the college broke ground ona new facility, the Anschutz Engineering Center,slated to open for classes in January 2024, says Sue McClernan, the colleges career and industry outreach program director. Student and workforce demand prompted the new degree, and we believe the Bachelor of Science in Aerospace Engineering at UCCS is well suited for a thriving aerospace economy in Colorado Springs and the region.

AeroSpace Ventures brings together researchers, students, industry leaders, government partners, and entrepreneurs to envision and create the future for space and Earth systems. This initiative is helping to drive the discovery and innovation that will shape the 21stcenturysaerospaceeconomy, says George Hatcher III, executive director of industry and foundation relations at CU Boulder. AeroSpace Ventures brings together CU Boulder departments, institutes, centers, and programsacross the universityto amplify the more than $120 million in aerospace-related research that happens on campus each year.

CU Boulder also hosts the Space Weather Technology, Research and Education Center to serve as a catalyst site for space weather research and technology development among CU and other Front Range space research and technology organizations. The campus also hosts the Center for National Security Initiatives. It provides high-impact national security research to government and industry partners and addresses the ever-increasing demand for qualified and experienced aerospace and defense professionals in Colorado and across the nation.

From LASPs humble beginnings 75 years ago, the University of Colorado has developed into an epicenter of space research and aerospace workforce development crucial to Coloradoand our nation.

Founded a decade before NASA, the Laboratory for Atmospheric and Space Physics at the University of Colorado Boulder is on a mission to transform human understanding of the cosmos by pioneering new technologies and approaches to space science. LASP is the only academic research institute in the world to have sent instruments to every planet in our solar system. LASP began celebrating its 75th anniversary in April 2023.

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CU to showcase 75 years of innovation and impact at the 38th ... - University of Colorado Boulder

Could a Rogue Planet Destroy the Earth? – Newsweek

The vast universe is filled with strange and mysterious phenomena, from quasars and black holes to the Botes void. One bizarre element in space is rogue planets, worlds just like our own, untethered by a star, wandering free and alone through the abyss.

Could one of these lonely planets find its way to our own solar system or even collide with the Earth?

Rouge planets, also known as free-floating planets, are thought to be a result of gravitational interactions in the early days of the formation of solar systems. Or they could be a result of the failed formation of stars.

"Modern theories of planetary system formation suggest that many planets are formed around young stars when they are in the short-lived phase of growing their planetary systems. But many of these are ejected due to gravitational scattering as the planetary systems organize themselves over time," Michael Zemcov, an associate professor of physics at the Rochester Institute of Technology, told Newsweek.

As a solar system forms, numerous chunks of rock of varying sizes and speeds whirl around each other in chaotic orbits. As these bodies soar past each other, they alter the orbits of other bodies as a result of their gravity.

"In typical three-body interactions characteristic of these ejection events, it is usually the lowest-mass object that gets ejected," Zemcov said. "So I think a generic prediction of these 'clearing out' episodes during planetary system formation is that the heavier objectswhether rocky or, more likely, ice or gas giantssurvive and the smaller ones don't."

Rogue planets may also come from another source, which is a star that failed to ignite and instead became stuck as a lone gas giant.

"They might form out of gas clouds in space, in the same way stars do, or they may have formed in a disc around a star and then been ejected due to an encounter with another star or an interaction with another planet in the same system," Richard Parker, a lecturer in astrophysics at the University of Sheffield in the U.K., told Newsweek.

"In the former case, they are likely to be predominantly gas giants like Jupiter. In the latter case, they could be rocky like Earth," he said.

Scientists aren't sure how many rogue planets are in our Milky Way galaxy since they are extremely hard to observe.

"[There are] likely many billions, or more, but they are ferociously hard to see," Zemcov said. "They would emit very little light on their own, mostly at very long wavelengths that are extremely difficult to pick out of the background emission. As a result, our primary way of detecting them is via gravitational microlensing, where we monitor a field of stars and then look for the light of a background source being temporarily magnified by the mass of a rogue planet as it passes precisely between our telescopes and the background star.

He continued: "We have found many objects this way, but without other information the lensing objects are impossible to weigh. So we don't have a good idea of demographics except in the general sense that larger things should be easier to see just because their temporary magnification is brighter and longer."

While we don't have a true idea of the number of rogue planets, scientists expect it is large.

"We expect a really big population," Alberto Fairn, a planetary scientist and astrobiologist at Cornell University, told Newsweek. "Think this way: The smallest the object in our galaxy, the larger the number of them we expect."

According to Dorian Abbot, a geophysical sciences professor at the University of Chicago, it is likely that most rogue planets are terrestrial because there are probably more terrestrial planets in general.

"It's easier to throw them out through an interaction with a gas giant because they are less massive. But gas giants can be ejected too. The Hot Jupiters detected in [around] 1 percent of systems suggest major dynamical evolution of those systems since Jupiters have to form where it is cold. This dynamical evolution could be associated with generating rogue planets," Abbot told Newsweek.

With all these invisible planets zipping around the galaxy, could one enter our solar system or even collide with the Earth?

"Assuming that there is a rogue planet for every star in the Milky Way, and we assume the solar system will be in a similar region of the galaxy over its lifetime, then I would estimate that the likelihood of a rogue planet coming within the solar system over the next 1,000 years to be a 1 in a billion chance," Garrett Brown, a celestial mechanics and computational physics researcher at the University of Toronto, told Newsweek.

"Here, I define 'coming within the solar system' to mean that we could see the rogue planet in such a way that when we look at it with a telescope it would look like Neptune or Pluto," Brown said. "For a rogue planet that were to come at least this close, there would be a 1 in 2,000 chance that it would directly alter Earth's orbit."

He continued: "It's difficult to say how likely it would be to actually collide with Earth without a more detailed analysis, but it would be much, much less likely. Thus, I would estimate the likelihood of a rogue planet coming closer to the Earth than Mars or Venus to be 1 in 2 trillion in the next 1,000 years. If there is one heading our way within the next 1,000 years, it would currently be about 0.2 light-years away."

Even if a rogue planet came close to the Earth, the interaction may not even destroy the planet if there wasn't a direct hit.

"It would need to come close enough to Earth to either collide with it or, a bit less unlikely, alter its orbit. If it does collide, this would be at high speed and likely destroy Earth, if it is comparable in mass and density to Earth," Jacco van Loon, an astrophysicist at Keele University, told Newsweek.

"A planet like Jupiter might even swallow Earth. Or Earth might come out the other way if it is a grazing encounter, but probably without its atmosphere," he said.

Rather than destroying the Earth, a passing rogue planet could even bump our planet out of orbit and cause it to become a rogue planet itself.

"I would say the more scary thing, rather than a direct collision, is having the Earth be scattered by a brief encounter by, say, an exo-Neptune passing through, which would move us to a different orbit or perhaps eject us from the solar system altogether," Zemcov said. "Then we would likely all freeze, or possibly cook, in a matter of weeks. That said, I am not losing any sleep over such a possibility."

It's very unlikely that interactions of the planets already in our solar system could suddenly boot Earth out into the abyss, thanks to our planet's orbits having had billions of years to settle into an equilibrium.

"One open and extremely good question is why our own solar system has been stable over 4.5 billion years," Zemcov said. "In many ways, it shouldn't be. As an example, some models for planet formation suggest that Jupiter was formed much closer in and then somehow migrated out to where it is today, likely by exchanging momentum with something that got ejected from our solar system."

He continued: "How we might retain the four rocky planets in the inner solar system in such a scenario is a complete mystery. And then we look around our solar system and see evidence for massive disruptionsfor example, Uranus rotating on its side. And it's clear that over astronomical time scales the details of these [solar systems] are not terribly robust."

One possibility is that there were once more planets in our early solar system but one was ejected as a rogue planet, leaving the solar system to never return.

"What's possible is that our sun would have ejected a rogue billions of years ago, when Jupiter and Saturn traveled from their original inner orbits to their actual positions. That's a scenario we cannot discard but we cannot confirm either," Fairn said.

Could a planet be ejected after life has evolved on its surface, or could life evolve after the planet left its star?

"Another much more interesting, to me, possible feature of rogue planets [is] the possibility that they can host life," Lorenzo Iorio, an astronomy and astrophysics professor at the Italian Ministry of Education, Universities and Research, told Newsweek.

Even without a star, life could be sustained under certain conditions. According to the Planetary Society, if a rogue planet had a large moon that orbited at close quarters, it could keep the center of the planet hot enough so that life could exist in volcanic vent environments.

So, while a rogue planet's collision would likely spell the end of life on Earth, such planets may be capable of hosting their own unique ecosystems.

Do you have a tip on a science story that Newsweek should be covering? Do you have a question about rogue planets? Let us know via science@newsweek.com.

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Could a Rogue Planet Destroy the Earth? - Newsweek

Does the sun really belong in its family? Astronomers get to the … – Space.com

The sun is having an identity crisis: Because it shows different magnetic activity and rotation rates than other stars in its current classification, scientists have debated whether the sun is really like the other stars in its family.

Now, the debate may finally be settled, as an investigation has found that the sun does indeed belong in this group.

The research was led by ngela Santos, a scientist at the Institute of Astrophysics and Space Sciences in Portugal, whose work focuses primarily on how solar and stellar rotation and stellar magnetic activity change as stars evolve. She explained the controversy over the sun's classification.

Related: Our sun is a weirdly 'quiet' star and that's lucky for all of us

"In the community, there is an ongoing debate on whether the sun is a 'sun-like' star," Santos said in a statement (opens in new tab). "In particular, about its magnetic activity; several studies suggested that stars similar to the sun were significantly more active. However, the problem doesn't seem to be with the sun, but with the stars classified as sun-like, because there are several limitations and biases in the observational data and the inferred stellar properties."

To investigate the question of whether the sun is truly a sun-like star, Santos and the team turned to data from NASA's now-retired Kepler space telescope, the European Space Agency's (ESA) Gaia mission, and the NASA-ESA Solar and Heliospheric Observatory (SOHO).

They focused on multiple stars that have similar stellar properties and magnetic activity to the sun and compared the data with observations of the sun's last two 11-year solar cycles collected by SOHO, which launched in 1995.

One star featured in the data, which is nicknamed "Doris" and officially designated KIC 8006161, is a blue star of a similar size and mass to the sun. The researchers had previously noted that the amplitude of Doris' stellar cycle was twice that of the last two solar cycles, indicating that Doris became twice as strong as our star, even though the two stars were similar in many ways.

The difference was caused by a disparity in the proportions of elements heavier than hydrogen and helium that make up the two stars' compositions. Astronomers call elements heavier than helium "metals," and they refer to the proportion of these elements as the "metallicity" of the star. Doris has a higher metallicity than the sun, and the researchers linked this difference to stronger activity.

"The difference was the metallicity," Santos said. "Our interpretation is that the effect of metallicity, which leads to a deeper convection zone, produces a more effective dynamo, which leads to a stronger activity cycle."

The researchers then went back and disregarded metallicity to select stars from their catalogs that demonstrated similar behavior to Doris. They found that most of these stars also had high metallicities, though Doris was still the most active of these stars.

"In our selection, the only parameter that could lead to this excess is the rotation period," Santos said. "In particular, Doris had a longer period than the sun. And, in fact, we found evidence of a correlation between the rotation period and metallicity."

In addition, despite being younger than the sun, Doris rotates more slowly. This is typical; astrophysicists think all stars are born spinning and slow down, or "spin down," as they age. This slowdown happens because of a phenomenon called "magnetic braking," in which material is caught by the star's magnetic field and eventually flung into space, carrying some of the sun's angular (rotational) momentum with it.

Doris' stronger magnetic activity is causing more magnetic braking, leading it to spin more slowly than the sun, the researchers explained.

Despite some key differences, however, the sun fits in nicely with a family of stellar objects aptly called sun-like stars, the team concluded.

"What we found is that although there are stars which are more active than the sun, the sun is indeed a completely normal sun-like star," Santos said.

The research was published in the April edition of the journal Astronomy & Astrophysics (opens in new tab).

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Kenya’s Third Attempt to Launch First 3U Observation Satellite Delayed – Voice of America – VOA News

Taifa 1, Kenya's first operational 3U nanosatellite, was set to launch aboard the SpaceX Falcon 9 rocket from the Vandenberg Space Force Base in the U.S. state of California on Friday after being delayed twice. But the launch was scrubbed at the last minute because of unfavorable weather.

Teddy Warria, with Africa's Talking Limited, a high-tech company, traveled to the University of Nairobi in Kenya from Kisumu, 563 kilometers west of Nairobi. He said he'll stay as long it takes to witness the historic day.

"It shows us through science, technology, engineering and mathematics, and if we apply the lessons learned from STEM, we can go as far as our minds and imagination can take us," Warria said.

Regardless of the delay, Charles Mwangi, the acting director of space sector and technology development at the Kenya Space Agency, said the satellite is quite significant.

"... [I]t's initiating conversations we've not been having in terms of what our role within the space sector should be," Mwangi said. "How do we leverage the potential space to address our societal need. More importantly, how do we catalyze research and activities of developing systems within our region."

FILE - Delegates attend the preparation of the launch of Kenya's first operational 3U Earth observation satellite, the Taifa-1, at the University of Nairobi's Taifa Hall, in Nairobi, Kenya, April 11, 2023.

Mwangi told VOA that launching the satellite will have some major benefits "that will help us in monitoring our forests, doing crop prediction, determine where the yield for our crops, disaster management, planning."

The satellite was developed by nine Kenyan engineers and cost $385,000 to build. The engineers collaborated with Bulgarian aerospace manufacturer Endurosat AD for testing and parts.

Pattern Odhiambo, an electrical and electronics engineer at the Kenyan Space Agency, who worked on the Taifa 1 mission, said, "I took part in deciding what kind of a camera we are supposed to have on this mission, so that we can meet the mission's objectives, which is to take images over the Kenyan territory for agricultural use, for urban planning, monitoring of natural resources and the likes."

And, as the communication subsystem lead, he also had other tasks.

"I took part in the design of the radio frequency link between the satellite and the ground station, the decision-making process on the kind of modulation schemes you can have on the satellite, the kind of transmitter power, the kind of antenna you are supposed to have," he said.

Samuel Nyangi, a University of Nairobi graduate in astronomy and Astro physics, was also at the university to witness his country's history making.

"If you look at the African countries that are economically strong Nigeria, South Africa, Egypt they all have very strong space industries. We are so proud of the Kenya Space Agency, having taken this initiative, because the satellite data that we use [is] from foreign nations, specifically NASA in the United States. For us having our own data, tailoring it to our own needs as Kenyans, it's a very big step," Nyangi said.

This sentiment is echoed by Paul Baki, professor of Physics at the Technical University of Kenya, who participated in a panel discussion on education and research to help answer students' questions. Baki told VOA this is a big leap for Kenya.

"We have walked this journey, I think, for over 20 years when the first draft space policy was done in 1994," Baki said. "We've decided that we are going to walk the talk and build something domestically. It has happened in approximately three years, which to me is no mean feat, and this is quite inspiring to our students because they have something to look up to."

Student James Achesa, who is in his fourth year studying mechanical engineering at Nairobi University, explained his understanding of the Taifa 1 mission.

"It'll help the small-scale farmer, as well as just general people in Kenya to see and understand where our country is going to. So, they might not enjoy the science of putting a spacecraft into space, but the science that does will come and disseminate to them at grassroots levels and will help them plan for their future," Achesa said.

Ivy Kut, who has a bachelor's degree in applied sciences and geoinformatics from the Technical University of Kenya, said, "It's going to benefit Kenyans in that we are going to get our own satellite data with better resolution and that is going to inform a lot of decisions in all sectors, especially in the analysis of earth data."

The next launch attempt is scheduled for Saturday.

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TOI-733 b – A Planet In The Small-planet Radius Valley Orbiting A … – Astrobiology News

RV (top panel) and FWHM (bottom panel) time-series. The purple markers in each panel represent the HARPS RV and FWHM measurements with inferred offsets extracted. The inferred multi-GP model is shown as a solid black curve, where the dark and light shaded areas show the 1- and 2- sigma credible intervals from said model, and can also explain the data but with a correspondingly lower probability. The solid red line in the top panel shows the star-only model, while the teal sine curve the Keplerian for TOI-733 b. In both panels the nominal error bars are in solid purple, and the jitter error bars (HARPS) are semi-transparent purple. astro-ph.EP

We report the discovery of a hot (Teq 1055 K) planet in the small planet radius valley transiting the Sun-like star TOI-733, as part of the KESPRINT follow-up program of TESS planets carried out with the HARPS spectrograph. TESS photometry from sectors 9 and 36 yields an orbital period of Porb = 4.884765+1.9e52.4e5 days and a radius of Rp = 1.992+0.0850.090 R.

Multi-dimensional Gaussian process modelling of the radial velocity measurements from HARPS and activity indicators, gives a semi-amplitude of K = 2.230.26 m s1, translating into a planet mass of Mp = 5.72+0.700.68 M. These parameters imply that the planet is of moderate density (p = 3.98+0.770.66 g cm3) and place it in the transition region between rocky and volatile-rich planets with H/He-dominated envelopes on the mass-radius diagram.

Combining these with stellar parameters and abundances, we calculate planet interior and atmosphere models, which in turn suggest that TOI-733 b has a volatile-enriched, most likely secondary outer envelope, and may represent a highly irradiated ocean world one of only a few such planets around G-type stars that are well-characterised.

Iskra Y. Georgieva, Carina M. Persson, Elisa Goffo, Lorena Acua, Artyom Aguichine, Luisa M. Serrano, Kristine W. F. Lam, Davide Gandolfi, Karen A. Collins, Steven B. Howell, Fei Dai, Malcolm Fridlund, Judith Korth, Magali Deleuil, Oscar Barragn, William D. Cochran, Szilrd Csizmadia, Hans J. Deeg, Eike Guenther, Artie P. Hatzes, Jon M. Jenkins, John Livingston, Rafael Luque, Olivier Mousis, Hannah L. M. Osborne, Enric Palle, Seth Redfield, Vincent Van Eylen, Joseph D. Twicken, Joshua N. Winn, Ahlam Alqasim, Kevin I. Collins, Crystal L. Gnilka, David W. Latham, Hannah M. Lewis, Howard M. Relles, George R. Ricker, Pamela Rowden, Sara Seager, Avi Shporer, Thiam-Guan Tan, Andrew Vanderburg, Roland Vanderspek

Comments: Accepted for publication in A&ASubjects: Earth and Planetary Astrophysics (astro-ph.EP)Cite as: arXiv:2304.06655 [astro-ph.EP] (or arXiv:2304.06655v1 [astro-ph.EP] for this version)Submission historyFrom: Iskra Georgieva[v1] Thu, 13 Apr 2023 16:35:36 UTC (3,171 KB)https://arxiv.org/abs/2304.06655Astrobiology

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NASAs TESS celebrates fifth year scanning th – EurekAlert

Now in its fifth year in space, NASAs TESS (Transiting Exoplanet Survey Satellite) remains a rousing success. TESSs cameras have mapped more than 93% of the entire sky, discovered 329 new worlds and thousands more candidates, and provided new insights into a wide array of cosmic phenomena, from stellar pulsations and exploding stars to supermassive black holes.

Using its four cameras, TESS monitors large swaths of the sky called sectors for about a month at a time. Each sector measures 24 by 96 degrees, about as wide as a persons hand at arms length and stretching from the horizon to the zenith. The cameras capture a total of 192 million pixels in each full-frame image. During its primary mission, TESS captured one of these images every 30 minutes, but this torrent of data has increased with time. The cameras now record each sector every 200 seconds.

The volume of high-quality TESS data now available is quite impressive, said Knicole Coln, the missions project scientist at NASA's Goddard Space Flight Center in Greenbelt, Maryland. We have more than 251 terabytes just for one of the main data products, called full-frame images. Thats the equivalent of streaming 167,000 movies in full HD.

TESS extracts parts of each full-frame image to make cutouts around specific cosmic objects more than 467,000 of them at the moment and together they create a detailed record of changing brightness for each one, said Christina Hedges, lead for the TESS General Investigator Office and a research scientist at both the University of Maryland, Baltimore County and Goddard. We use these files to produce light curves, a product that graphically shows how a sources brightness alters over time.

To find exoplanets, or worlds beyond our solar system, TESS looks for the telltale dimming of a star caused when an orbiting planet passes in front of it. But stars also change brightness for other reasons: exploding as supernovae, erupting in sudden flares, dark star spots on their rotating surfaces, and even slight changes due to oscillations driven by internal sound waves. The rapid, regular observations from TESS enable more detailed study of these phenomena.

Some stars give TESS a trifecta of brightness-changing behavior. One example is AU Microscopii, thought to be about 25 million years old a rowdy youngster less than 1% the age of our Sun. Spotted regions on AU Mics surface grow and shrink, and the stars rotation carries them into and out of sight. The stormy star also erupts with frequent flares. With all this going on, TESS, with the help of NASAs now-retired Spitzer Space Telescope, discovered a planet about four times Earths size orbiting the star every 8.5 days. Then, in 2022, scientists announced that TESS data revealed the presence of another, smaller world, one almost three times Earths size and orbiting every 18.9 days. These discoveries have made the system a touchstone for understanding how stars and planets form and evolve.

Here are a few more of the missions greatest hits:

New discoveries are waiting to be made within the huge volume of data TESS has already captured. This is a library of observations astronomers will explore for years, but theres much more to come.

Were celebrating TESSs fifth anniversary at work and wishing it many happy returns! Coln said.

TESS is a NASA Astrophysics Explorer mission led and operated by MIT in Cambridge, Massachusetts, and managed by NASA's Goddard Space Flight Center. Additional partners include Northrop Grumman, based in Falls Church, Virginia; NASAs Ames Research Center in Californias Silicon Valley; the Harvard-Smithsonian Center for Astrophysics in Cambridge, Massachusetts; MITs Lincoln Laboratory; and the Space Telescope Science Institute in Baltimore. More than a dozen universities, research institutes, and observatories worldwide are participants in the mission.

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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NASAs TESS celebrates fifth year scanning th - EurekAlert

Unraveling new insights on cosmic explosions – Asiana Times

A tremendous pulse of gamma-ray radiation that swept through our solar system on October 9, 2022, overwhelmed the gamma-ray detectors on multiple orbiting satellites and sent astronomers on the run to investigate the event using the most potent telescopes in the world.

The newly discovered source, designated GRB 221009A in honor of the time it was found, ended up becoming the brightest gamma-ray burst (GRB) ever observed.The gamma-ray burst, which lasted for more than 300 seconds, is thought to be the first sign of the birth of a black hole, which is created when the center of a large, rapidly spinning star shatters under the weight of itself.At nearly light speed, powerful plasma jets are ejected from the growing black hole, penetrating the falling star and emitting gamma rays.

Observations of GRB 221009A from radio waves to gamma rays, including crucial millimeter-wave observations with the Centre for Astrophysics | Harvard & Smithsonians Submillimeter Array (SMA) in Hawaii, shed new light on the decades-long quest to understand the origin of these extreme cosmic explosions, according to a new study that appears today in the Astrophysical Journal Letters.

What would happen after the initial burst of gamma rays was the mystery of GRB 221009A, the brightest explosion ever seen. The studys principal author is Tanmoy Laskar, an assistant professor of physics and astronomy at the University of Utah. According to him, a dazzling afterglow of light spanning the entire spectrum is produced as the jets collide with the gas surrounding the dying star. We must be quick and nimble to capture the light before it vanishes and take its secrets because the afterglow fades because the afterglow fades pretty quickly, he added.

In an effort to employ the greatest radio and millimetre telescopes in the world to analyse the afterglow of GRB 221009A, astronomers Edo Berger and Yvette Cendes of the Centre for Astrophysics (CfA) immediately obtained data with the SMA.

Garrett Keating, a SMA project scientist and CfA researcher, states they were able to swiftly turn the SMA to the site of GRB 221009A due to its capacity to respond quickly. The crew was impressed by the brightness of the GRBs afterglow, which we could observe for more than 10 days before it faded.

Astronomers were perplexed when they combined and analyzed data from the SMA and other telescopes around the world and discovered that the millimeter and radio wave measurements were significantly brighter compared to what the visible and X-ray radiation would suggest.

According to Cendes, CfA research associate, one explanation is that the potent jet created by GRB 221009A is more complicated than in other GRBs. Its likely that one part of the jet produces visible light and X-rays while another part generates radio waves and early millimeter waves.

According to researchers, this afterglow is so intense that we will keep looking into its radio emission for months, if not years. With this much longer time span, they hope to solve the riddle of the early excess emissions mysterious origin.

Unrelated to the specifics of this GRB, astronomers now have a crucial new skill: the capacity to react quickly to GRBs and other comparable phenomena with millimeter-wave telescopes.

According to Edo Berger, professor of astronomy at Harvard University and the CfA, the key lesson from this GRB is that without fast-acting radio and millimeter telescopes, such as the SMA, We would not be able to learn more about the most intense explosions in the cosmos. If we want to benefit from these gifts from the cosmos, we have to be as responsive as we can because we never know when such events will occur.

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Unraveling new insights on cosmic explosions - Asiana Times

Ved Chirayath is on a mission to map the world’s oceans – University of Miami: News@theU

The University of Miami professor, National Geographic Explorer, inventor, and fashion photographer has created and developed next-generation remote sensing instruments capable of mapping the seafloor in remarkable detail.

One misstep and Ved Chirayath would have been a goner. Cut off from civilization and his cell phone useless, he knew that medical aid would never reach him in time if he were bitten by one of the countless sea snakes that surrounded him.

Theyre curious creatures, the University of Miami researcher and National Geographic Explorer said of the highly venomous snakes. Theyll swim right up to you and lick you. And when they sleep, they sleep head down in the rocks. So, my real concern was not to step on one.

But despite the very real prospect of death, Chirayath concentrated on the task at hand: mapping a colony of stromatolites in Australias snake-infested Shark Bay.

He would spend the entire two months of that 2012 field campaign navigating around the deadly snakes, the thought of dying only occasionally entering his mind. His unquenchable thirst for knowledge allowed him to stay focused.

Its that same thirst that drives him today in his quest to explore Earths last unexplored frontier: its oceans.

We have mapped more of Mars and our Moon than we have of our planets seafloor, and we know more about the large-scale structure of our universe and its history than we do about the various systems in our oceans, said Chirayath, the G. Unger Vetlesen Professor of Earth Sciences at the Rosenstiel School of Marine, Atmospheric, and Earth Science. And we know so much more about our universe because we can see very far into space and in different wavelengths.

Peering into the deep ocean, however, is another matter. Light penetrates only so far below the sea surface, and ocean waves greatly distort the appearance of undersea objects.

But using a camera he invented that literally sees through ocean waves, Chirayath is removing those distortions and helping to reveal the trove of deep secrets hidden by our oceans. Mounted on a drone flying above the water, FluidCam uses a technology called Fluid Lensing to photograph and map the ocean in remarkable clarity. From American Samoa and Guam to Hawaii and Puerto Rico, he has used the device to map more than a dozen shallow marine ecosystems such as coral reefs at depths as low as 63 feet.

That still pales in comparison to the average depth of the ocean, which is nearly 4,000 meters. And 99 percent of the habitable volume of our planet is in that region, said Chirayath, who also directs the Rosenstiel Schools Aircraft Center for Earth Studies (ACES).

So, he created the more powerful MiDAR. The Multispectral Imaging, Detection, and Active Reflectance device combines FluidCam with high-intensity LED and laser light pulses to map and transmit 3D images of the sea floor at greater detail and depths. Chirayaths research will be on display April 2021 at the Universitys showcase exhibit during the eMerge Americas conference at the Miami Beach Convention Center.

Recently, he used MiDAR to conduct multispectral mapping of corals in Guam, validating the airborne images during subsequent dives.

Still, even MiDAR will not illuminate objects 4,000 meters deep. But install the device on a robot sub that can dive thousands of meters deep, and the possibilities of imaging the seafloor in the same detail and volume that satellites have mapped land are limitless, according to Chirayath.

It keeps me up at night, he said of MiDARs potential. He envisions his creation, awarded NASAs invention of the year in 2019, exploring not only the Earths deep oceans but worlds beyondfrom sampling minerals on Mars to looking for signs of life beneath the icy ocean moons like Jupiter's Europa.

Chirayaths fascination with studying and surveying the ocean deep was born out of his love of the stars.

He grew up in Los Angeles, looking up at the stars and contemplating the possibility of life on other planets. As a youngster, he would attend open house events at NASAs Jet Propulsion Laboratory in nearby Pasadena, learning from the scientists and engineers who were building the Cassini space probe that explored Saturn and its intricate rings.

I knew at 5 years old that I wanted to work for NASA and make a contribution to discovering other worlds, Chirayath said.

By the time he was a teenager, astronomy had been his passion for more than half his life. It was also an escape, a methodology, he said, to deal with some of the challenges he faced at that time. I was homeless for about three years, and I used that time to sit on top of a mountain and do as much astronomy as I could, Chirayath noted.

At 16, he detected an exoplanet one and a half times the size of Jupiter and 150 light years from Earth in the constellation Pegasus, doing so with a consumer digital camera he modified and attached to a telescope. His refashioned scope allowed him to employ the transit photometry method for detecting exoplanets. Whenever a planet passes directly between a star and its observer, it dims the stars light ever so slightly. Chirayaths modified telescope detected just such a dip in light.

Earth- and space-based observatories that look continuously at stars for weeks and even months at a time use the technique. It took Chirayath three years to locate the planet, but his patience paid off in the form of a scholarship he won and used to help study theoretical physics at Moscow State University in Russia.He later transferred to Stanford University, where he earned his undergraduate degree.

To help pay the bills while he attended college, he worked as a fashion photographer for Vogue. His pictures have also appeared in Elle, The New York Times, and Vanity Fair.

He earned his Ph.D. in aeronautics and astronautics from Stanford University, reconnecting with his passion for astronomy and always asking himself, What can I do with small telescopes? How can I make an impact? How can I develop new technologies and explore our solar system?

He came to the University of Miami in 2021 after a decade-long career at NASAs Ames Research Center, where he founded and led its Laboratory for Advanced Sensing, inventing the suite of next-generation remote sensing technologies that are now the cornerstones of his work at ACES.

While at NASA, he also created NeMO-Net, a single player video game in which players help NASA classify coral reefs. The space agency awarded Chirayath with its 2016 Equal Employment Opportunity Medal for organizing its first participation in the San Francisco LGBT Pride Parade.

His fluid lensing mapping of the ocean promises to improve the resilience of coastal areas impacted by severe storms as well as assess the effects of climate change on coastal areas around the world.

While his origins are in astronomy, today he is more of a marine scientist than an astrophysicist. Still, the two fields are incredibly similar, Chirayath pointed out. Theyre both very difficult to study and require thinking beyond our terrestrial comfort zone. I love them both, and they can easily coexist. You can have large space observatories, and they can even help one another. A lot of the technologies that Ive created were inspired by things I learned in astrophysics and applied astronomy. But theres not that curiosity for understanding our own planet in a way that there is for space, and Im hoping to change that.

He applauds the $14 billion James Webb Space Telescope, which has been taking the deepest infrared images of our universe ever taken.

But weve never invested $14 billion into an ocean observatory, into something that looks critically at a piece of the puzzle that if we miss, we do so at our own peril, Chirayath explained. Im one of the many technologists who are looking inward and saying, This is what we understand about the universe and its large-scale structure, but a lot of the questions that are being posed to understand our universe and whats in it can also be posed for the ocean. If we dont map it, if we dont understand it, if were not able to characterize it, then when it fails or changes, humans may not be a part of the future.

The University of Miami is a Titanium Sponsor of eMerge Americas. Visit the Universitys research and technology showcase April 2021 at the Miami Beach Convention Center. Registration for an Unlimited TECH Pass is free for all University of Miami students and faculty and staff members.

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Ved Chirayath is on a mission to map the world's oceans - University of Miami: News@theU

Multinucleon transfer creates short-lived uranium isotope – Interesting Engineering

According to a report, scientists have discovered and produced a new type of uranium isotope, known as uranium-241.

This is the first time a new neutron-rich isotope of uranium has been discovered since 1979, and it was identified by researchers at the High-energy Accelerator Research Organization located in Japan. Uranium-241 is an extremely radioactive element with 92 protons and 149 neutrons, and it is predicted to have a brief half-life of around 40 minutes.

Uranium, one of the most radioactive elements, is a member of the actinide series, which includes all elements with atomic numbers between 89 and 103. Uranium-241 is known as a neutron-rich isotope because it has more neutrons than is typical for uranium isotopes. This discovery has significant implications for the study of nuclear and astrophysics, as well as our understanding of heavy elements' behavior and stability.

The researchers utilized a technique called multinucleon transfer to create uranium-241 by firing uranium-238 at platinum-198 nuclei using Japan's RIKEN accelerator. The resulting nuclei were observed to determine their mass as they traveled a certain distance through a medium. This process led to the creation of 18 new isotopes with between 143 and 150 neutrons.

The discovery of uranium-241 illustrates the capabilities of modern particle accelerators and experimental methods in advancing scientific knowledge and exploration. The collision of atomic nuclei at high speeds and energies enables the creation and study of short-lived and exotic isotopes that were previously unobservable and unobtainable.

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Multinucleon transfer creates short-lived uranium isotope - Interesting Engineering

Pharmacogenomics | National Institutes of Health (NIH)

In the 1970s, NIH research gave us genetic engineering and launched what is today the $100 billion biotechnology industry, a major source of high-paying U.S. jobs. Virtually every biomedical research lab and pharmaceutical company uses the power of the genomic revolution every day to demystify diseases and search for new cures. Companies today can read the entire DNA sequence of an individual for less than $1,000, and the cost is dropping quickly. This ability to study massive amounts of DNA has helped the field of pharmacogenomics mature rapidly. In this area of science, researchers match DNA patterns in individuals with how they respond to medications. The goal is to move away from one-size-fits-all dosing because we now know that many factors aside from sex, age, and body size influence how our bodies react, ordont, to many drugs. Research results in this important area of biomedicine have prompted FDA to include pharmacogenomic information in drug labeling, toward more precise and safer drug responses for patients. A significant goal of precision medicine is to implement this strategy broadly in medical care focusing on the right drug at the right dose at the right time for the right patient.

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Pharmacogenomics | National Institutes of Health (NIH)

Nanotechnology – Definition and Introduction – Nanowerk

Nanotechnology deals with the understanding and control of matter at dimensions between approximately 1 and 100 nanometers, where unique phenomena enable novel applications.

Dimensions between approximately 1 and 100 nanometers are known as the nanoscale.

Some examples to demonstrate the size of the nanoscale. ( Nanowerk) (click on image to enlarge)

The term was coined in 1974 by Norio Taniguichi of of Tokyo Science University to describe semiconductor processes such as thin-film deposition that deal with control on the order of nanometers. His definition still stands as the basic statement today: "Nano-technology mainly consists of the processing of separation, consolidation, and deformation of materials by one atom or one molecule."

Many argue that the history of nanotechnology starts with Richard Feynman's classic talk in December 1959: There's Plenty of Room at the Bottom - An Invitation to Enter a New Field of Physics:

Unusual physical, chemical, and biological properties can emerge in materials at the nanoscale. These properties may differ in important ways from the properties of bulk materials and single atoms or molecules.

The bulk properties of materials often change dramatically with nano ingredients. Composites made from particles of nano-size ceramics or metals smaller than 100 nanometers can suddenly become much stronger than predicted by existing materials-science models.

For example, metals with a so-called grain size of around 10 nanometers are as much as seven times harder and tougher than their ordinary counterparts with grain sizes in the hundreds of nanometers. The causes of these drastic changes stem from the weird world of quantum physics. The bulk properties of any material are merely the average of all the quantum forces affecting all the atoms. As you make things smaller and smaller, you eventually reach a point where the averaging no longer works.

The properties of materials can be different at the nanoscale for two main reasons:

Surface Area

Quantum Size Effects

Second, quantum effects can begin to dominate the behavior of matter at the nanoscale particularly at the lower end affecting the optical, electrical and magnetic behavior of materials. This effect describes the physics of electron properties in solids with great reductions in particle size. This effect does not come into play by going from macro to micro dimensions. However, it becomes dominant when the nanometer size range is reached.

The fascination with nanotechnology stems from these unique quantum and surface phenomena that matter exhibits at the nanoscale. They improve existing industrial processes, materials and applications in many fields and allows entirely new ones.

With regard to nanoscale materials, there are plenty of examples we could talk about here nanoparticles, quantum dots, nanowires, nanofibers, ultrathin-films, MXenes, etc.

One example, though, that is exemplary of how an 'old' material gets an exciting new life through nanoscale technologies is the element carbon.

Current applications of nanomaterials include very thin coatings used, for example, in electronics and active surfaces (such as self-cleaning windows). In most applications the nanomaterial will be fixed or embedded but in some, such as those used in cosmetics and in some environmental remediation applications, free nanoparticles are used. The ability to engineer materials to very high precision and accuracy (smaller than 100nm) is leading to considerable benefits in a wide range of industrial sectors, for instance in the production of components for the information and communication technology, automotive and aerospace industries.

A mite, less than 1 mm in size, approaching a microscale gear chain. (Image: Sandia National Laboratories)

Some 20-30 years ago, microelectromechanical systems (MEMS) emerged in industrial manufacturing in a major way. MEMS consist of any combination of mechanical (levers, springs, membranes, etc.) and electrical (resistors, capacitors, inductors, etc.) components to work as sensors or actuators. The size of today's smartphones would be impossible without the use of numerous MEMS devices. Apart from accelerometers and gyroscopes, smartphones contain micro-mirrors, image sensors, auto-focus actuators, pressure sensors, magnetometers, microphones, proximity sensors and many more. Another example from everyday life is the use of MEMS as accelerometers in modern automobile airbags where they sense rapid deceleration and, if the force is beyond a programmed threshold, initiate the inflation of the airbag.

Then, researchers took a further step down the size scale and have begun exploring another level of miniaturization nanoelectromechanical systems (NEMS). NEMS are showning great promise as highly sensitive detectors of mass, displacement, charge, and energy.

In some senses, nanoscience and nanotechnologies are not new. Chemists have been making polymers, which are large molecules made up of nanoscale subunits, for many decades and nanotechnologies have been used to create the tiny features on computer chips for the past 30 years.

However, advances in the tools that now allow individual atoms and molecules to be examined and probed with great precision have enabled the expansion and development of nanoscience and nanotechnologies. With new tools came new fundamental concepts and it turned out that the mechanical rules that govern the nanoworld are quite different from our everyday, macroworld experience.

Today there are a number of tools that can be used to characterize the nanomechanics of biomolecular and cellular interactions. Besides cantilever-based instruments like the AFM, examples include optical tweezers, and magnetic pullers.

Nano tech improves existing industrial processes, materials and applications by scaling them down to the nanoscale in order to ultimately fully exploit the unique quantum and surface phenomena that matter exhibits at the nanoscale. This trend is driven by companies' ongoing quest to improve existing products by creating smaller components and better performance materials, all at a lower cost.

A prime nanotechnology example of an industry where nanoscale manufacturing technologies are employed on a large scale and throughout is the semiconductor industry where device structures have reached the single nanometers scale. Your smartphone, smartwatch or tablet all are containing billions of transistors on a computer chip the size of a finger nail.

So, what can nanotechnology do? There is almost no field today where nanotechnology isn't applied in some form or shape as things like surface coatings, sensors, electronic components, membranes, etc. in medicine, environmental remediation, water filtration, nanoelectronics, food and agriculture, cosmetics, energy and batteries, space and aeronautics, automotive industries, displays, sports equipment and many more.

If you select "Introduction to Nanotechnology" from our menu bar above you will find numerous articles on all these topics in the right column.

Many products are defined as "nanotechnology product" because they contain nanoparticles in some form or other. For instance, many antimicrobial coatings contain silver in nanoscale form; food products and cosmetics contain nanoparticles; and some products are partially made with composite materials containing nanomaterials (e.g. carbon nanotubes or -fibers) to mechanically strengthen the material.

"Nanotech" products that are on the market today are mostly gradually improved products (using evolutionary nanotechnology) where some form of nano-enabled material (such as carbon nanotubes, graphene, nanocomposite structures or nanoparticles of a particular substance) or nanotech process (e.g. nanopatterning or quantum dots for medical imaging) is used in the manufacturing process.

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Nanotechnology - Definition and Introduction - Nanowerk

What is B-Love Network & How to earn Money in B-love Network?

A smartphone app that lets you stake BLV tokens, invite referrals and earn lovely rewards.

  • Powered By
  • B-LOVE Token

B-Love Token (BLV) is a community-reward token deployed on the BFIC Blockchain. The BLV token has a maximum supply of 20 billion tokens, and will follow a progressive supply burn mechanism to elevate the internal value.

Earn 5x Rewards

The B Love Network app has been designed to reward each user with 5x rewards. With a 1% daily reward, the B-Love Network plan will reward the users for a time period of 500 days.

Explore the B-Love Network Plan in detail

Initial Token Offering (ITO)

  • Phase 1 : Internal price  $0.0125
  • Phase 2 : Internal price  $0.03
  • Phase 3 : Internal price  $0.06

Swap to get

B-Love Tokens   B-Love tokens will be exclusively available on XchangeOn.io and Dexa.exchange. BLV tokens can be obtained by swapping BFICoins for BLV tokens. Else, users can also purchase BLV tokens through ITOs conducted at XchangeOn.io.

Rewards

The only staking platform that offers 5x Returns! Stake as many BLV tokens as you want, and get 5 times in rewards.

  • 1% Daily Rewards
  • 500 Days Staking Period

Referral Program

Invite your friends, colleagues and family members to join through your referral code and earn additional rewards. These rewards are categorized as Associate Rewards or Team Rewards.

Associate/Team Levels & Rewards

Earn associate rewards up to 15 levels. Each team level has its prescribed percentage of reward. The higher your team level, the more will be your aggregate associate rewards.

A Community Token Designed to Spread Love & Success

 

What is B-Love Token?

B-Love Network Sign Up - B-Love Network

B-Love Token (BLV) is a community-reward token deployed on the BFIC Blockchain. The BLV token has a maximum supply of 20 billion tokens, and will follow a progressive supply burn mechanism to elevate the internal value.

Native Token of Love Wallet

  • Love Wallet is the official wallet for BLV Token.
  • BLove token is the native token of Love Wallet.

Love Wallet is a decentralized multi-chain wallet to store & swap crypto coins & NFTs.

Buy your B-Love token from centralized per to per XchangeOn Platform and get the initial token offering (ITO)

Register on Xchangeon.io or download the XchangeOn App from google playstore

  • Swap BLV token with BFICoin
  • Despoit BFIC in your XchangeOn account

Transfer BLV tokens to B love Network App and start staking.

Buy with Dexa

Swap or exchange your B-LOVE token from DEXA advanced decentralized exchange & trade platform for NFTs & Crypto Assets. The platform houses its own NFT marketplace & asset swap portal.

  • Register on Dexa.exchange
  • Link your Love Wallet or MetaMask wallet
  • Go to dexa.exchange/swap
  • Swap your USDB or BFIC for BLV tokens

 

10% Supply Burn

Conclusion

The supply of B-Love tokens will be controlled by burning mechanism. Each month, 10% of the initial supply will be burned. With the passive burning on monthly basis, the internal price of B-Love tokens will continue to increase.

B-love Network is a crypto-staking platform that has been designed in a simplified that even someone who is an amateur in crypto can earn from this platform.

Earning on B-love Network is as easy as tapping on the Heart Button Daily.

Three types of rewards can be earned on B-love Network.

  • Daily Rewards.
  • Direct rewards.
  • Associate rewards.

Daily Rewards is dependent on the amount of BLV Tokens Staked. The more Blv Tokens staked, the more daily rewards can be earned.

Direct rewards come from a multi-level marketing feature within B-love Network. B-love Network advocates users to refer their friends and family, and by so doing, they earn rewards for every new user that they refer. The more people someone refers, the more rewards they earn.

The last type of reward is associate rewards. Let’s say you refer 2 people, who refer 2 more people, all these people will be under your team and will garner you “associate rewards” The more people you have in your team, the more rewards you will get.

B-love Network has endless earning potential. There is no limit to the amount of BLV tokens you can stake or the number of people you can add to your team.

The price of BLV tokens is constantly increasing. Just last week, it increased in price from $0.02 to $0.03 and there is very high probability that it will see exponential growth.

B-love Token is the perfect opportunity to create a source of passive income. You can earn effortlessly from wherever you are in the world

 

Biochemistry: Definition And Explanation – University of the People

Biochemistry is exciting and fascinating science, and this article will tell you everything youve been wanting to know about the field. Well give you the full biochemistry definition: the basics, the history, as well as the promising degrees and careers you can expect in the biochemists laboratory and beyond.

Biochemistry, or biological chemistry, is the branch of science that studies chemical and physicochemical processes within living organisms.

Source: Pexels

As a combination of biology and chemistry, biochemistry studies the chemical substances and processes which occur within the biology of the body or any living organisms.

Biochemists study large molecules such as carbohydrates and proteins in relation to metabolism and other important processes within the body. Other molecules that biochemists may study include enzymes and DNA. These types of molecules are important for understanding the complex processes which occur in all living organisms.

The term biochemistry was created by Carl Neuberg, a German chemist, in 1902. But the study itself has been around for over 400 years, essentially since the invention of the microscope in 1665 by Robert Hooke. The microscope made it possible to study cells.

In 1674, Anton van Leeuwenhoek was the first to observe live plant cells under the microscope, which opened up many more possibilities than the dead cells which were being observed up until then. Live cells allowed scientists to observe chemical processes that occurred within and between them.

In the 18th century, a notable discovery in the field was made by the French scientist, Antoine Lavoisier, who proposed the concept of photosynthesis, a process in which plants convert water, sunlight, and carbon dioxide into their nutrients. Lavoisier was also the first person to study cell respiration, which is the process of making the energy molecule in the cells mitochondria.

In the 20th century, DNA was acknowledged as the genetic material which made up the cell. This was established by James Watson and Francis Crick based on the research work of Rosalind Franklin.

Most recently, new technology continues to advance scientific studies in areas such as recombinant DNA, gene splicing, radioisotopic labeling, and electron microscopy.

A career in biochemistry is recommended for those who enjoy research, as it is generally a career in laboratory science. Most careers in the field require at least a bachelors degree, such as a position as a laboratory technician. Other positions, such as laboratory managers or principal investigators of research, will require a masters degree or a Ph.D.

Laboratory technicians engage in bench work and help perform experiments in the lab under the instruction of the principal investigators. Technicians need a bachelors degree in order to be qualified, but more education and research will allow for more independence in the lab.

Lab managers carry more responsibility in the laboratory and may conduct independent research under the guidance of the principal investigator.

Though a masters degree in the field will require an emphasis on research, a Ph.D. prepares biochemists for a career in independent research, principal investigators of research in laboratories, and lecturers in university.

There are also many industry positions available to biochemists. Biochemists may also work in governmental labs or for companies in agriculture, pharmaceuticals, public health, or biotechnology. Some biochemists may also work in services such as toxicology and forensics.

Source: Pexels

As one may imagine, a contender for biochemistry needs to have a good understanding of both biology and chemistry. Some universities may offer a specific biochemistry track, or students can begin their education by taking a bachelors degree in either biology or chemistry, with a minor in the other.

Biochemists also need to have a good grasp of mathematics and statistics in order to conduct research. As students advance in their studies, they will begin to hone in on their particular interests.

Similar studies include health sciences, which offer courses in biology, anatomy, biostatistics, and disease prevention. Universities such as the University of the People (UoPeople) offer associates and bachelors degrees in health science completely online and tuition-free. The university also offers potential certificate programs in health science that can give ones career the right boost.

As weve seen, the biochemistry definition includes a rich history and an exciting future for further discoveries. Since the invention of the microscope, biochemists have been investigating the complex, hidden world of cells and molecules.

Biochemistry is an exciting and constantly evolving field of science with an emphasis on research and laboratory technology. Different levels of education open up many opportunities for working in the field. If you have a passion for this science, then biochemistry may be a meaningful career choice for you.

Link:
Biochemistry: Definition And Explanation - University of the People

Scientist Discovers Aging Clock to Speed and Reverse Aging | Time

Its been 13 years in the making, but Dr. David Sinclair and his colleagues have finally answered the question of what drives aging. In a study published Jan. 12 in Cell, Sinclair, a professor of genetics and co-director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, describes a groundbreaking aging clock that can speed up or reverse the aging of cells.

Scientists studying aging have debated what drives the process of senescence in cellsand primarily focused on mutations in DNA that can, over time, mess up a cells normal operations and trigger the process of cell death. But that theory wasnt supported by the fact that older peoples cells often were not riddled with mutations, and that animals or people harboring a higher burden of mutated cells dont seem to age prematurely.

Sinclair therefore focused on another part of the genome, called the epigenome. Since all cells have the same DNA blueprint, the epigenome is what makes skin cells turn into skin cells and brain cells into brain cells. It does this by providing different instructions to different cells for which genes to turn on, and which to keep silent. Epigenetics is similar to the instructions dressmakers rely on from patterns to create shirts, pants, or jackets. The starting fabric is the same, but the pattern determines what shape and function the final article of clothing takes. With cells, the epigenetic instructions lead to cells with different physical structures and functions in a process called differentiation.

In the Cell paper, Sinclair and his team report that not only can they age mice on an accelerated timeline, but they can also reverse the effects of that aging and restore some of the biological signs of youthfulness to the animals. That reversibility makes a strong case for the fact that the main drivers of aging arent mutations to the DNA, but miscues in the epigenetic instructions that somehow go awry. Sinclair has long proposed that aging is the result of losing critical instructions that cells need to continue functioning, in what he calls the Information Theory of Aging. Underlying aging is information that is lost in cells, not just the accumulation of damage, he says. Thats a paradigm shift in how to think about aging.

His latest results seem to support that theory. Its similar to the way software programs operate off hardware, but sometimes become corrupt and need a reboot, says Sinclair. If the cause of aging was because a cell became full of mutations, then age reversal would not be possible, he says. But by showing that we can reverse the aging process, that shows that the system is intact, that there is a backup copy and the software needs to be rebooted.

In the mice, he and his team developed a way to reboot cells to restart the backup copy of epigenetic instructions, essentially erasing the corrupted signals that put the cells on the path toward aging. They mimicked the effects of aging on the epigenome by introducing breaks in the DNA of young mice. (Outside of the lab, epigenetic changes can be driven by a number of things, including smoking, exposure to pollution and chemicals.) Once aged in this way, within a matter of weeks Sinclair saw that the mice began to show signs of older ageincluding grey fur, lower body weight despite unaltered diet, reduced activity, and increased frailty.

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The rebooting came in the form of a gene therapy involving three genes that instruct cells to reprogram themselvesin the case of the mice, the instructions guided the cells to restart the epigenetic changes that defined their identity as, for example, kidney and skin cells, two cell types that are prone to the effects of aging. These genes came from the suite of so-called Yamanaka stem cells factorsa set of four genes that Nobel scientist Shinya Yamanaka in 2006 discovered can turn back the clock on adult cells to their embryonic, stem cell state so they can start their development, or differentiation process, all over again. Sinclair didnt want to completely erase the cells epigenetic history, just reboot it enough to reset the epigenetic instructions. Using three of the four factors turned back the clock about 57%, enough to make the mice youthful again.

Were not making stem cells, but turning back the clock so they can regain their identity, says Sinclair. Ive been really surprised by how universally it works. We havent found a cell type yet that we cant age forward and backward.

Rejuvenating cells in mice is one thing, but will the process work in humans? Thats Sinclairs next step, and his team is already testing the system in non-human primates. The researchers are attaching a biological switch that would allow them to turn the clock on and off by tying the activation of the reprogramming genes to an antibiotic, doxycycline. Giving the animals doxycycline would start reversing the clock, and stopping the drug would halt the process. Sinclair is currently lab-testing the system with human neurons, skin, and fibroblast cells, which contribute to connective tissue.

In 2020, Sinclair reported that in mice, the process restored vision in older animals; the current results show that the system can apply to not just one tissue or organ, but the entire animal. He anticipates eye diseases will be the first condition used to test this aging reversal in people, since the gene therapy can be injected directly into the eye area.

We think of the processes behind aging, and diseases related to aging, as irreversible, says Sinclair. In the case of the eye, there is the misconception that you need to regrow new nerves. But in some cases the existing cells are just not functioning, so if you reboot them, they are fine. Its a new way to think about medicine.

That could mean that a host of diseasesincluding chronic conditions such as heart disease and even neurodegenerative disorders like Alzheimerscould be treated in large part by reversing the aging process that leads to them. Even before that happens, the process could be an important new tool for researchers studying these diseases. In most cases, scientists rely on young animals or tissues to model diseases of aging, which doesnt always faithfully reproduce the condition of aging. The new system makes the mice very old rapidly, so we can, for example, make human brain tissue the equivalent of what you would find in a 70 year old and use those in the mouse model to study Alzheimers disease that way, Sinclair says.

Beyond that, the implications of being able to age and rejuvenate tissues, organs, or even entire animals or people are mind-bending. Sinclair has rejuvenated the eye nerves multiple times, which raises the more existential question for bioethicists and society of considering what it would mean to continually rewind the clock on aging.

This study is just the first step in redefining what it means to age, and Sinclair is the first to acknowledge that it raises more questions than answers. We dont understand how rejuvenation really works, but we know it works, he says. We can use it to rejuvenate parts of the body and hopefully make medicines that will be revolutionary. Now, when I see an older person, I dont look at them as old, I just look at them as someone whose system needs to be rebooted. Its no longer a question of if rejuvenation is possible, but a question of when.

More Must-Reads From TIME

Write to Andrew D. Johnson at andrew.johnson@time.com.

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Scientist Discovers Aging Clock to Speed and Reverse Aging | Time

When Should You Take Resveratrol? – Healthgrades

Resveratrol has been in the news on and off over the last few decades. Headlines have touted resveratrol in skin care, weight loss, heart health, and several other conditions. Its a naturally occurring compound called a polyphenol. You can find it in certain foods and as a resveratrol supplement. Heres what you need to know about resveratrol, including how to safely include it in your diet or start a resveratrol supplement regimen.

Resveratrolor trans-resveratrolis a chemical with antioxidant properties. Antioxidants help cells resist damage from unstable atoms called free radicals. Over 70 plant species have detectable levels of it, with Japanese knotweed having the highest content. Scientists believe plants make it to protect themselves against pathogens and natural radiation.

Several foods contain resveratrol, including grapes, blueberries, cranberries and peanuts. Red wine has the highest concentration of resveratrol for foods. This is thanks to the amount of time grape skins spend in fermentation to make red wine. Resveratrols presence in red wine is one reason you may have heard it touted as heart-healthy. It first started with the so-called French Paradoxthe low rate of heart disease in French people despite their high consumption of saturated fats. Red wine was at the center of explaining the paradox because the French consume a lot of it. When scientists started studying compounds in red wine, they found resveratrol.

Laboratory and animal studies have suggested several resveratrol benefits. Even human studies have shown positive results in certain markers of disease. However, there are few well-controlled human studies. And results havent been able to show clear-cut gains in health and survival, despite the changes in disease biomarkers. The list of potential resveratrol benefits includes:

More research is necessary before scientists can say for certain whether any of these resveratrol benefits are real or not.

People tend to think that natural means safe. People also tend to think over-the-counter products are generally safe. In fact, all drugs, including herbal or natural supplements, have potential safety issues. With resveratrol, some of its beneficial actions can also be problems in the wrong person.

People who should not take resveratrol include:

In general, resveratrol has few side effects. However, diarrhea and other digestive symptoms are possible at high doses.

As with any vitamin or natural product, the best place to get resveratrol is in your diet. It cant hurt to add foods that contain it to your diet. And if you already enjoy a glass of red wine, youre probably getting some resveratrol as a bonus.

If youre looking to add a resveratrol supplement, its best to talk with your doctor first. Make sure its potential biologic actions wont be harmful for you based on your medical history or the medications you take. Then, choose the right supplement.

Most resveratrol supplements contain some combination of extracts from grape seeds, red wine, berries, and Japanese knotweed. Japanese knotweed has the highest concentration in plants, so its often a first ingredient on the label. However, Japanese knotweed extracts also contain the chemical emodin, which can cause diarrhea. If you develop digestive upset with a resveratrol supplement, check to see if its from Japanese knotweed extract. Switching to a different resveratrol extract may help.

After verifying the ingredients, look for micronized resveratrol on the label. Resveratrol is hard for the body to absorb and use. Micronizing the compound makes it easier for your body to absorb and use it. Resveratrol liquid and patches are also available.

Keep in mind, the FDA (Food and Drug Administration) regulates supplements as foods, not drugs. Manufacturers dont have to provide the same purity, safety and efficacy proof that drug makers do. So, its important to do your homework. Buy a resveratrol supplement made by a reputable manufacturer.

Also, look for certification stamps on the label, but be careful. Some manufacturers put misleading stamps to make them look official. Reliable stamps include USP, CL and NSF. Manufacturers with these stamps have voluntarily had their products tested for purity. A stamp from one of these organizations validates the content claims on the label are true. These stamps arent an endorsement of safety or efficacy.

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When Should You Take Resveratrol? - Healthgrades