Miami Heat: Strong team chemistry is the key to continued success – Hoops Habit

If youve ever ordered a dirty Chai oat milk latte, you know the pain of paying too much for a dose of caffeine. And yet, your drink of choice still probably doesnt come close to the $20 Cup of Joe that Miami Heat star Jimmy Butler is offering up in the NBA playoffs.

Yes, you read that right Butler started his very own side gig in the NBA bubble, taking full advantage of the fact that its seemingly slim pickings in the coffee department out there in Orlando.

And while Big Face Coffee might seem inconsequential to Miamis quest for a title, its anything but.

The Heat are currently 6-0 in postseason play, most recently earning a Game 2 win over the Milwaukee Bucks on Wednesday night. They also previously dominated the Indiana Pacers in the Eastern Conference Quarterfinals, despite T.J. Warrens best attempts to get under Butlers skin.

Now its true that the 2019-20 roster is loaded with raw talent.

Butler, since arriving in South Florida, has blossomed into a bonafide superstar. Bam Adebayo arguably should have been a viable Most Improved Player of the Year recipient. Goran Dragic, an already elite point guard at every phase of his career, has taken his game to a whole new level. Tyler Herro is undoubtedly one of the leagues top rookies. Duncan Robinson has continued to break several franchise records with his sharp-shooting.

You get the picture.

But what has brought this team success as a unit, is strong chemistry, both on and off the court.

Me and Jimmy, we have great chemistry, Dragic said of Butler. As a team, we have great chemistry.One of our emphases before the playoffs was enjoy the game. Enjoy it. Have that smile on your face. Thats what I love to do.

Dragics work hard, play hard mentality is certainly shared by his teammates, who have visibly grown even closer since the NBA Restart. Between bench celebrations and Instagram shoutouts, its clear Miami is the definition of a ride or die squad, havingforged a true brotherhood that in turn, translates into untouchable chemistry on the floor.

Because these guys respect each other so much as human beings first and foremost, theyre able to put full trust in one another when it comes to in-game decisions.

Take Jae Crowder for example, who only joined the Heat in a February trade.

Although he certainly still isnt the teams primary choice when it comes to three-point shooting, Miami has allowed him to grow in that role because of the trust theyve formed as a group.

Jae is a competitor, a warrior, Dragic explained. Hes accepting every challenge Hes shooting the ball really well. We want to find him in the offense.

Butler and Crowder have obviously formed a bond on their own too.

(Bet you didnt think Id circle back to Big Face Coffee, did you?)

Miamis unparalleled chemistry has led to unshakeable confidence in guys to create successful plays, move the ball seamlessly and make tough shots. The entirety of the group having each others backs is what made them so vigilant against Indiana and so fearless against the Milwaukee Bucks. They are truly playing team ball, game after game, consistently propping one another up and leaving all egos at the door.

NBA playoffs and beyond, youll be hard-pressed to find a more cohesive (and caffeinated) team, than the Miami Heat.

See original here:
Miami Heat: Strong team chemistry is the key to continued success - Hoops Habit

Ravens’ Jimmy Smith on Earl Thomas Release: ‘Chemistry Is Everything’ – Bleacher Report

Julio Cortez/Associated Press

Baltimore Ravens cornerback Jimmy Smith alluded to the behind-the-scenes friction with Earl Thomas when explaining why the team moved on from the star safety.

Smith told reporters that "chemistry is everything" and players on the team are expected to maintain "a certain culture."

The Ravensannouncedlast month they released Thomas, citing "personal conduct that adversely affected the Baltimore Ravens."

ESPN'sAdam Schefterreported the three-time All-Pro punched teammate Chuck Clark during a practice, which was the final straw for the team.Jason La Canforaof CBS Sports added that Baltimore's leadership council "made it clear to decision makers they would prefer Thomas not be around."

ESPN'sJamison Hensleywrote the problems with Thomas went beyond his altercation with Clark. He had an argument with Ravens nose tackle Brandon Williams last season and "also missed or was late to several meetings."

Thomas had 47 tackles, two sacks and two interceptions in 2019 en route to his seventh trip to the Pro Bowl. His value on the field isn't in doubt, but the timing of his release and circumstances behind his departure are probably hindering his chances of joining a new team ahead of the 2020 season.

Most coaches have already finalized their secondaries, and they might be wary of relying on Thomas given how quickly his Ravens tenure unraveled.

The Dallas Cowboysreleasedsafety Ha Ha Clinton-Dix on Thursday, naturally leading to speculation about a move for Thomas. ESPN'sTodd Archerand NFL Network'sJane Slaterboth threw cold water on that rumor for the time being.

Read the rest here:
Ravens' Jimmy Smith on Earl Thomas Release: 'Chemistry Is Everything' - Bleacher Report

Hair Dye and Cancer – The Chemistry Behind the Scare – American Council on Science and Health

There are so many chemicals accused of causing human cancers that it's a wonder that any of us are still breathing. Yet, we are. In fact, since 1975 rates of most cancers have been either steady or slowly declining (Figure 1). So, these claims must be false; either the chemicals in question are not really carcinogenic or humans are not being exposed to enough of them to make a difference.

Rates of cancers of all sites 1975-2020. Source: CDC

When friendsand relatives ask me whetherChemical A or Chemical B will give them cancer my reply is usually "nonsense." But not with hair dyes. There is a chemical in hair dyes called para-phenylenediamine, a/k/a4-aminoaniline, or PPD,that at least warrants some respect and consideration. At least as seen through the eyes of a chemist. Here's why.

The chemical structure andfour common names of PPD

PPD itself is not carcinogenic (1), but it is rather toxic. Some people develop skin hypersensitivity that can be rather nasty. But other chemicals are used in the dying process; one of them is hydrogen peroxide. Peroxide reacts with PPD to give something calledBandrowski's base (Figure 2, left), which is highly mutagenic and possibly carcinogenic. Bandrowski's base is a trimeric oxidation product of PPD. The three PPD units are shown in red ovals. The blue arrows indicate the chemically reactive (dangerous) portion of the molecule - the carbon-nitrogen double bonds.

Tylenol (Figure 2, right) provides a similar case - a molecule being activated by oxidization(in this case by the liver) to form something more dangerous than the parent compound. Tylenol itself is not harmful, but once oxidized by younow have in your blood aseriously bad liver toxin called N-acetylbenzoquinone imine (NAPQI), which is the bad actor, not Tylenol itself. The red arrow shows the chemically reactive (2) fragment of the molecule, a carbon-oxygen double bond.

Life doesn't always follow the rules of chemistry and biochemistry. It would be difficult for any well-trained medicinal chemist tolook at the structures of the oxidation products of PPD and Tylenol and not raise an eyebrow or two. While the structures of both oxidation products are potentially harmful, NAPQI(from Tylenol)is, while Bandrowski's base (from PPD) is not, at least no as used (3). Just one of the many quirks of organic chemistry. No reason to pull your hair out. Or let it get gray.

WHAT ABOUT HAIR DYE AND CARCINOGENICITY?

My colleague Alex Berezowjust published an article on the results of a very large 36-year study that looks at the hair dye-cancer link (or lack thereof). You can read his analysis here.

NOTES

(1) IARC(International Agency for Research on Cancer), a subsidiary of the WHO, isn't the least bit reluctant to label a chemical a carcinogen, deserved or not. But even they don't claim that PPD is a carcinogen. It is categorized as not classifiable as to its carcinogenicity to humans See my colleague Dr. Alex Berezow's vicious takedown of IARC's corrupt decision to categorize glyphosateas a carcinogen, even though it isn't.

(2) Chemical reactivity is almost always a big no-no in drugs. Reactive molecules modify different amino acids in proteins. Your body doesn't appreciate this.

(3) Why isBandrowski'snot carcinogenic? Hard to say. It could be any number of reasons, likeinsufficient exposure orlack of absorption through the skin. My money says it's the second.

More:
Hair Dye and Cancer - The Chemistry Behind the Scare - American Council on Science and Health

Analytical Chemistry Sample Preparation Market size and Key Trends in terms of volume and value 2020-2025 – CueReport

The Global Analytical Chemistry Sample Preparation market is growing at a faster pace with substantial growth rates over the last few years and is estimated that the market will grow significantly in the forecasted period i.e. 2020 to 2025. The Global Analytical Chemistry Sample Preparation market report provides a holistic evaluation of the market for the forecast period (20202025). The report comprises of various segments as well an analysis of the trends and factors that are playing a substantial role in the market. These factors; the market dynamics, involves the drivers, restraints, opportunities and challenges through which the impact of these factors in the market are outlined. The Global Analytical Chemistry Sample Preparation market study provides an outlook on the development of market in terms of revenue throughout the prognosis period.

Executive Summary:

Request Sample Copy of this Report @ https://www.cuereport.com/request-sample/43050

The recent Analytical Chemistry Sample Preparation market research report offers a brief overview of this industry landscape including insights pertaining to growth factors, limitations, opportunities and other future prospects influencing the business scenario.

Request Sample Copy of this Report @ https://www.cuereport.com/request-sample/43050

The Analytical Chemistry Sample Preparation market is anticipated to showcase a y-o-y growth rate of XX% during the period of 2020-2025.

Significant information regarding the regional scope, competitive terrain as well as the other factors impacting segmentations of this vertical are encompassed in the document. The report also evaluates the COVID-19 impact on the industry remuneration, citing top pointers to be considered during this pandemic.

Market Rundown:

Regional outlook:

Product spectrum:

Application scope:

Competitive landscape:

Some of the key questions answered in this report:

What will the market growth rate, growth momentum or acceleration market carries during the forecast period?

Which are the key factors driving the Analytical Chemistry Sample Preparation market?

What was the size of the emerging Analytical Chemistry Sample Preparation market by value in 2019?

What will be the size of the emerging Analytical Chemistry Sample Preparation market in 2025?

Which region is expected to hold the highest market share in the Analytical Chemistry Sample Preparation market?

What are sales volume, revenue, and price analysis of top manufacturers of Analytical Chemistry Sample Preparation market?

What are the Analytical Chemistry Sample Preparation market opportunities and threats faced by the vendors in the global Analytical Chemistry Sample Preparation Industry?

Request Customization on This Report @ https://www.cuereport.com/request-for-customization/43050

See more here:
Analytical Chemistry Sample Preparation Market size and Key Trends in terms of volume and value 2020-2025 - CueReport

Aluminiumnitrogen batteries offer alternative ammonia synthesis | Research – Chemistry World

A newly developed battery based on aluminium, nitrogen and a specialised ionic liquid electrolyte can be used for energy storage via a net reaction that produces aluminium nitride by breaking the challenging nitrogennitrogen triple bond. Aluminium nitride can be converted to ammonia, opening a new avenue for coupling energy generation and the production of nitrogen-containing compounds, without relying on industrial routes that contribute to global warming.

Batteries based on gases can simultaneously store and release energy while also converting gaseous components to new compounds. These compounds may act as precursors to industrially relevant chemicals. For example, Li-CO2 batteries work by exploiting the electrochemical reduction of carbon dioxide to form a lithium carbonate. This carbonate can react further to create a range of different chemicals.

However, lithium is a somewhat costly metal that is also to difficult to handle. To overcome this limitation, a battery developed by the team of Chunyi Zhi at the City University of Hong Kong instead targets aluminium and nitrogen. This avoids the need for an expensive alkali metal anode and by incorporating nitrogen as the gaseous component, it provides a new route to ammonia that avoids the HaberBosch process.

Focusing on low-cost and naturally abundant aluminium as the metal anode allowed Zhi and co-workers to better engineer the underlying electrochemical reaction. This was achieved using an aluminium-based ionic liquid electrolyte instead of the ether-based electrolytes found in competing Li-N2 batteries. The crucial point of the AlCl/1-butyl-3-methylimidazolium chloride electrolyte is its Lewis acidity, which enables the electroplating or stripping of aluminium on the anode because this process can only take place in acidic conditions, explains Zhi.

Using aluminium metal alongside this specific ionic liquid electrolyte allowed for a net reaction during battery discharge that involves reacting aluminium with nitrogen to afford aluminium nitride, a process that has a greater thermodynamic driving force than the production of Li3N in LiN2 batteries. The resulting aluminium nitride, which forms at the cathode during battery operation, may then be reacted with sodium hydroxide, readily forming ammonia.

This is an interesting and more environmentally friendly alternative to the HaberBosch process to produce ammonia. Moreover, replacing lithium with aluminium in metalnitrogen batteries would potentially reduce costs and increase the energy density of the battery, says Adriana Navarro-Surez who researches electrochemical energy storage at Imperial College London, UK.

However, Navarro-Surez notes an issue with the cathode and associated electrocatalyst within the battery. Currently, the cathode of the aluminiumnitrogen battery is based on graphene and palladium, the latter of which is a precious and costly metal. Yi-Chun Li, a battery specialist at the Chinese University of Hong Kong, also highlights this issue and while she notes that a battery which successfully harnesses nitrogen to produce aluminium nitride is impressive, future work on replacing precious metal catalysts with other low-cost catalysts is important for large scale practical applications.

Zhi and his team are actively considering this imposition to scale-up and widespread commercialisation. They intend to design special electrocatalysts based on other metals or metal oxides. They are also considering carbon-free catalysts and more stable electrolytes that would boost the energy conversion efficiency of the aluminiumnitrogen battery by avoiding parasitic reactions.

Original post:
Aluminiumnitrogen batteries offer alternative ammonia synthesis | Research - Chemistry World

The Right Chemistry: Maybe it’s time to smell the roses – Montreal Gazette

It isnt surprising that a popular flower like the rose should have invited investigation for possible medicinal properties over the ages. The ancient Greek physician Dioscorides recommended an elixir of roses cooked in wine for headaches, while in the Americas, Indigenous people treated colds, coughs and fevers with various potions derived from the flowers, leaves or roots of the plant. Rosewater has also been used cosmetically, incorporated into creams for its supposed anti-inflammatory properties.

Such traditional uses, while mostly anecdotal, have stimulated some serious research into potential medicinal properties, especially since roses do contain numerous terpenes, glycosides, flavonoids and anthocyanins with potential pharmacological effects. Unfortunately, virtually all the studies have been carried out in animals or in cell culture with a paucity of human data. For example, aromatherapists have claimed that rose essential oil can have a soothing, sleep-inducing effect. However, the citations provided deal with mice. When mice are put to sleep with a barbiturate, their sleeping time increases if their food is supplemented with some rose extracts. Only specific extracts work, and only at doses far greater than any to which humans would be exposed. Furthermore, the extracts were ingested, not inhaled.

Read the original here:
The Right Chemistry: Maybe it's time to smell the roses - Montreal Gazette

Healthcare Nanotechnology (Nanomedicine) Market : Updates, Future Growth, Industry Analysis And Comprehensive Study On Key Players To 2020 2028 -…

Healthcare Nanotechnology (Nanomedicine) Market is analyzed with industry experts in mind to maximize return on investment by providing clear information needed for informed business decisions. This research will help both established and new entrants to identify and analyze market needs, market size and competition. It explains the supply and demand situation, the competitive scenario, and the challenges for market growth, market opportunities and the threats faced by key players.

Sample Copy of This Report: https://www.quincemarketinsights.com/request-sample-64780?utm_source=st/ARSHAD

A 360 degree outline of the competitive scenario of the Global Healthcare Nanotechnology (Nanomedicine) Market is presented by Quince Market Insights. It has a massive data allied to the recent product and technological developments in the markets.

It has a wide-ranging analysis of the impact of these advancements on the markets future growth, wide-ranging analysis of these extensions on the markets future growth. The research report studies the market in a detailed manner by explaining the key facets of the market that are foreseeable to have a countable stimulus on its developing extrapolations over the forecast period.

Sanofi SA, Pfizer Inc., Celgene Corporation, Luminex Corporation, and Taiwan Liposome Company Ltd.

Reasons for buying this report:

By Application (Drug Delivery, Biomaterials, Active Implants, Diagnostic Imaging, Tissue Regeneration), By Disease (Cardiovascular Diseases, Oncological Diseases, Neurological Diseases, Orthopedic Diseases, Infectious Diseases and Other Diseases)

Healthcare Nanotechnology (Nanomedicine)

Get ToC for the overview of the premium report @ https://www.quincemarketinsights.com/request-toc-64780?utm_source=st/ARSHAD

A detailed outline of the Global Healthcare Nanotechnology (Nanomedicine) Market includes a comprehensive analysis of different verticals of businesses. North America, Latin America, Asia-Pacific, Africa, and Europe have been considered for the studies on the basis of several terminologies.

This is anticipated to drive the Global Healthcare Nanotechnology (Nanomedicine) Market over the forecast period. This research report covers the market landscape and its progress prospects in the near future. After studying key companies, the report focuses on the new entrants contributing to the growth of the market. Most companies in the Global Healthcare Nanotechnology (Nanomedicine) Market are currently adopting new technological trends in the market.

Finally, the researchers throw light on different ways to discover the strengths, weaknesses, opportunities, and threats affecting the growth of the Global Healthcare Nanotechnology (Nanomedicine) Market. The feasibility of the new report is also measured in this research report.

Make an Enquiry for purchasing this Report @ https://www.quincemarketinsights.com/enquiry-before-buying-64780?utm_source=st/ARSHAD

Table of Contents:

ABOUT US:

QMI has the most comprehensive collection of market research products and services available on the web. We deliver reports from virtually all major publications and refresh our list regularly to provide you with immediate online access to the worlds most extensive and up-to-date archive of professional insights into global markets, companies, goods, and patterns.

Contact:

Quince Market Insights

Ajay D. (Knowledge Partner)

Office No- A109

Pune, Maharashtra 411028

Phone: APAC +91 706 672 4848 / US +1 208 405 2835 / UK +44 144 439 0986

Email: [emailprotected]

Web: https://www.quincemarketinsights.com

Here is the original post:
Healthcare Nanotechnology (Nanomedicine) Market : Updates, Future Growth, Industry Analysis And Comprehensive Study On Key Players To 2020 2028 -...

Nanomedicine Market Segmentation By Qualitative And Quantitative Research Incorporating Impact Of Economic And Non-Economic Aspects By 2027 – Reports…

The report on the Global Nanomedicine Market provides a panoramic view of the current developments and progresses within the Nanomedicine market. The report further analyzes the impact of the novel COVID-19 pandemic on the Nanomedicine market and provides an accurate insight into the current and future market fluctuations. Factors likely to influence the growth of the market, current trends, opportunities, restraining factors, and business landscape are discussed in-depth in the market study.

The Nanomedicine market report further discusses the definitions, classifications, types, applications, market overview, manufacturing processes and costing, raw materials, among other key points. The report additionally provides SWOT analysis, investment feasibility, and investment return analysis.

Get a sample copy of the Nanomedicine market report @ https://www.reportsanddata.com/sample-enquiry-form/1048

The major players profiled in the global Nanomedicine market report include:

Arrowhead Pharmaceuticals Inc. AMAG Pharmaceuticals, Bio-Gate AG, Celgene Corporation, and Johnson & Johnson.

Market Segment by Regions:

Product Outlook (Revenue, USD Billion; 2017-2027)

Drug Delivery System Outlook (Revenue, USD Billion; 2017-2027)

Application Outlook (Revenue, USD Billion; 2017-2027)

Request a discount on the report @ https://www.reportsanddata.com/discount-enquiry-form/1048

Key Questions Answered in the Report:

Key takeaways from the Nanomedicine market report:

To read more about the Global Nanomedicine Market @ https://www.reportsanddata.com/report-detail/nanomedicine-market

Thank you for reading our report. For more information on customization, please reach out to us. Our team will ensure the report is tailored according to your needs.

Follow this link:
Nanomedicine Market Segmentation By Qualitative And Quantitative Research Incorporating Impact Of Economic And Non-Economic Aspects By 2027 - Reports...

NanoViricides is Developing Drugs Against SARS-CoV-2 with an Integrated Approach to Combat COVID-19, as Reported at The LD 500 Virtual Conference -…

SHELTON, CT / ACCESSWIRE / September 4, 2020 / NanoViricides, Inc. (NYSE American: NNVC) (the "Company") a global leader in the development of highly effective antiviral therapies based on a novel nanomedicines platform, today reported on the Presentation by Anil R. Diwan, Ph.D., its President and Executive Chairman, at the LD 500 investor conference yesterday, Thursday, September 3rd at 11:20 AM EDT.

Dr. Diwan presented the Company's rapid progress in developing a drug to attack the SARS-CoV-2 virus that causes COVID-19 spectrum of diseases.

He summarized the Company's progress since embarking into this endeavor with very limited resources since about January, 2020, and boot-strapping on its past work against coronaviruses. Dr. Diwan stated that the Company is close to declaring a clinical candidate for treating patients infected with SARS-CoV-2. The Company has previously reported that its development candidates have shown to be effective against multiple coronaviruses in the Company's own BSL2 Virology Lab, and have also shown to be highly effective in an animal study to combat infection by a related coronavirus that uses the same ACE2 receptor as does SARS-CoV-2.

Dr. Diwan stated that this broad-spectrum effectiveness against coronaviruses provides scientific reasoning that even as a field coronavirus strain mutates, our drug candidates would continue to remain effective, unlike antibodies and vaccines.

In addition, our current development candidates against COVID-19 have also been shown to be extremely safe in animal studies. Their effectiveness in cell culture and animal models has led us to believe that they are worthy of human clinical development.

Subsequently, the Company has completed CMC ("Chemistry, Manufacture, and Controls") studies that would be required for an IND ("Investigational New Drug) application to the U.S. FDA. The Company is also in the process of drafting sections of an IND for COVID-19 drug candidate. The Company is currently conducting studies to finalize its clinical candidate.

Dr. Diwan further stated the Company's intent of developing an integrated approach to combat SARS-CoV-2 that could potentially result in a cure for the virus. The virus lifecycle is a convolution of two parts: (a) re-infection of a host cell by external virus (after primary infection from outside the host body), and (b) replication (i.e. production of new virus particles) in infected cells and egress of the newly produced virus particles to feed back into the (a) re-infection cycle, completing the loop.

Dr. Diwan explained that if both parts of the virus lifecycle are blocked, then a virus infection would be cured, except in the case of latent viruses.

A nanoviricide® is uniquely capable of accomplishing this task of integrated attack against both the re-infection and replication mechanisms, as the Company has previously stated. The nanoviricide is already designed to block the re-infection cycle part. In addition, it can carry in its "belly", a payload that can block the replication cycle part.

NanoViricides has accelerated its anti-coronavirus program to develop a "second generation" nanoviricide against coronaviruses that is designed to block both re-infection and replication cycles, in addition to the current development of the "first generation" anti-coronavirus drug intended to block the re-infection cycle part. The Company accelerated these efforts due to both the severity of the pandemic, and the difficulty of curing the SARS-CoV-2 infection as exemplified by several recent unsuccessful or partially successful clinical studies.

In particular, the Company has successfully encapsulated remdesivir inside its current development drug candidates. The resulting drug, which is expected to be superior to remdesivir alone, as well as many other drugs, is already in pre-clinical testing, Dr. Diwan disclosed.

Remdesivir inhibits replication cycle by blocking the RNA polymerase activity essential for virus genome duplication. It is highly effective in cell culture studies against many viruses. However, its success in reducing viral load and pathology has been limited in human clinical studies. This is probably substantially due to the extensive metabolism that the drug is subjected to as soon as it enters the bloodstream.

Encapsulation into a nanoviricide is anticipated to protect remdesivir from this extensive metabolism and thus improve its clinical effect profile. Additionally, the nanoviricide itself is expected to block the re-infection cycle part of the virus lifecycle. Thus the Company believes that this novel integrated nanomedicine approach could produce a highly effective drug against coronaviruses, and against SARS-CoV-2 in particular, possibly on the way to a cure.

The Company develops its class of drugs, that we call nanoviricides®, using a platform technology. This approach enables rapid development of new drugs against a number of different viruses. A nanoviricide is a "biomimetic" - it is designed to "look like" the cell surface to the virus. The nanoviricide® technology enables direct attacks at multiple points on a virus particle. It is believed that such attacks would lead to the virus particle becoming ineffective at infecting cells. Antibodies in contrast attack a virus particle at only a maximum of two attachment points per antibody.

Because of the worldwide urgency of the pandemic caused by the SARS-CoV-2 virus, we have focused all our efforts recently on taking a drug against SARS-CoV-2 into human clinical trials for treatment of patients with COVID-19. An effective drug could potentially allow full-fledged opening of normal activities, including schools, businesses, and economies all over the world.

Soon after it files an IND for a COVID-19 drug candidate, the Company intends to re-engage its NV-HHV-101 shingles drug candidate clinical trials program towards IND filing. The Company has put the shingles program on hold due to perceived difficulties in conducting proposed shingles clinical trials during the COVID-19 pandemic. The Company is near finalizing the selection of clinical trial sites and finalizing clinical trial protocols for the shingles IND filing.

The NV-HHV-101 drug candidate is expected to open up a billion dollar market for the shingles treatment space, and also lead to further development of drugs against other herpesviruses such as HSV-1 that causes "cold sores" and HSV-2 that causes genital herpes. The multiple indications enabled by the HerpeCide program drug candidates may potentially address a several billion dollar marketspace.

For additional information about NanoViricides, please visit the company's website at http://www.nanoviricides.com .

About NanoViricides NanoViricides, Inc. (www.nanoviricides.com) is a development stage company that is creating special purpose nanomaterials for antiviral therapy. The Company's novel nanoviricide® class of drug candidates are designed to specifically attack enveloped virus particles and to dismantle them. Our lead drug candidate is NV-HHV-101 with its first indication as dermal topical cream for the treatment of shingles rash. The Company is in the process of completing an IND application to the US FDA for this drug candidate. The Company cannot project an exact date for filing an IND because of its dependence on a number of external collaborators and consultants, the effects of recent COVID-19 restrictions, and re-prioritization for COVID-19 drug development work.

The Company is also developing drugs against a number of viral diseases including oral and genital Herpes, viral diseases of the eye including EKC and herpes keratitis, H1N1 swine flu, H5N1 bird flu, seasonal Influenza, HIV, Hepatitis C, Rabies, Dengue fever, and Ebola virus, among others. NanoViricides' platform technology and programs are based on the TheraCour® nanomedicine technology of TheraCour, which TheraCour licenses from AllExcel. NanoViricides holds a worldwide exclusive perpetual license to this technology for several drugs with specific targeting mechanisms in perpetuity for the treatment of the following human viral diseases: Human Immunodeficiency Virus (HIV/AIDS), Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Rabies, Herpes Simplex Virus (HSV-1 and HSV-2), Varicella-Zoster Virus (VZV), Influenza and Asian Bird Flu Virus, Dengue viruses, Japanese Encephalitis virus, West Nile Virus and Ebola/Marburg viruses. The Company has executed a Memorandum of Understanding with TheraCour that provides a limited license for research and development for drugs against human coronaviruses. The Company intends to obtain a full license and has begun the process for the same. The Company's technology is based on broad, exclusive, sub-licensable, field licenses to drugs developed in these areas from TheraCour Pharma, Inc. The Company's business model is based on licensing technology from TheraCour Pharma Inc. for specific application verticals of specific viruses, as established at its foundation in 2005.

This press release contains forward-looking statements that reflect the Company's current expectation regarding future events. Actual events could differ materially and substantially from those projected herein and depend on a number of factors. Certain statements in this release, and other written or oral statements made by NanoViricides, Inc. are "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties and other factors which are, in some cases, beyond the Company's control and which could, and likely will, materially affect actual results, levels of activity, performance or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include, but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Although it is not possible to predict or identify all such factors, they may include the following: demonstration and proof of principle in preclinical trials that a nanoviricide is safe and effective; successful development of our product candidates; our ability to seek and obtain regulatory approvals, including with respect to the indications we are seeking; the successful commercialization of our product candidates; and market acceptance of our products. FDA refers to US Food and Drug Administration. IND application refers to "Investigational New Drug" application. CMC refers to "Chemistry, Manufacture, and Controls".

Contact: NanoViricides, Inc. info@nanoviricides.com

Public Relations Contact: MJ Clyburn TraDigital IR clyburn@tradigitalir.com

SOURCE: NanoViricides, Inc.

View source version on accesswire.com: https://www.accesswire.com/604794/NanoViricides-is-Developing-Drugs-Against-SARS-CoV-2-with-an-Integrated-Approach-to-Combat-COVID-19-as-Reported-at-The-LD-500-Virtual-Conference

Go here to see the original:
NanoViricides is Developing Drugs Against SARS-CoV-2 with an Integrated Approach to Combat COVID-19, as Reported at The LD 500 Virtual Conference -...

Impressive Trends and Future Scope of Nanocapsules Market – StartupNG

Nanopharmacology is a new branch of pharmacology which deals with the application of nanotechnology in the field of nanomedicine. This is a potential step towards curing and prevention of disease by using molecular knowledge about human body and molecular tools. Nanopharmacology studies the interaction between nanoscale drugs and proteins such as DNA, RNA and cells & tissues. It also studies the interaction between physiological systems and traditional drugs at nanoscale level.

View Report : https://www.transparencymarketresearch.com/nanocapsules-market.html

Nanoparticles are solid colloidal particles that include both nanospheres and nanocapsules. Nanocapsule is any nanoparticles that consist of a shell and a space in which desired substances may be placed. It is made up of a nontoxic polymer. They are also known to be drug delivery agents in the size range of 10-1000 nm. These capsules are made up of molecules called as phospholipids such as liposomes. Now-a-days many other materials such as variety of polymers have been used to make nanocapsules by self assembly process. Polymeric capsules are studied extensively as particulate carriers in the medical and pharmaceutical fields as they act as good drug delivery systems as a result of their sustained and control release property and subcellular size.

The ultrafine size of nanocapsules itself is one of the useful function as the finer drug are suitable to be absorbed easily through biological systems. The special features and functions of nanoparticles include slow release: the capsules releases drugs molecules slower over a long period of time, quick release: the capsule shell breaks and comes in contact with a surface, specific release: the shell is designed to break open when a molecule receptor binds to a specific chemical and moisture release: the shell breaks down and releases drug in the presence of water among other features. The state of the art nanocapsulation medications include drugs deliver to specific locations within the body, cuts down on the amount of drug per dose and reduces the risk of side effects. The only limitation is that it is designed to target pre-determined areas.

Get Brochure of the Report @https://www.transparencymarketresearch.com/sample/sample.php?flag=B&rep_id=5321

Cancer, neutraceuticals, ethyl alcohol absorption, food usage and self healing materials are the major applications of nanocapsules. Water soluble polymer shells are manufactured to deliver a protein known as apoptin into cancer cells. Neutraceuticals are substances which are placed into food to enhance nutrition. The smaller the nanocarrier, the better the delivery particles and solubility of neutraceuticals. Nanocapsulation in foods includes the changing of texture, coloring, flavoring and stability in shelf life. Nanocapsules are known to reduce damage that is caused by high loads for components in microelectronics, polymeric coatings and adhesives.

Growing pharmaceutical industry along with the rising demand for nanocapsules are expected to be the major factor driving the global nanocapsules industry. The growing demand from the end user industry is also expected to boost demand for nanocapsules in the near future.

Request For Covid19 Impact Analysis https://www.transparencymarketresearch.com/sample/sample.php?flag=covid19&rep_id=5321

Asia Pacific is expected to be the largest consumer of nanocapsules due to growing pharmaceutical industries in the region. North America and Europe are also expected to boost demand for nanocapsules owing to the growing demand from the end-user industries for various applications.

Read our Case study at :https://www.transparencymarketresearch.com/casestudies/innovative-medical-device-manufacturing-start-up

Some of the major players profiled for global nanocapsules market include: Capsulation, Sanzyme Ltd, PlasmaChem GmbH, NoCamels, Indian Instruments Manufacturing Company, Encap, Sintef, and Carlina Technologies among others.

More Trending Reports by Transparency Market Research 1.http://www.prnewswire.com/news-releases/increasing-number-of-accidents-and-injuries-to-drive-adoption-of-wound-closure-strips-market-valuation-to-rise-up-to-us446-3-mn-by-2027-end-finds-tmr-301019647.html

2.https://www.biospace.com/article/dna-test-kits-market-increase-in-demand-for-ancestry-testing-to-drive-market/

Originally posted here:
Impressive Trends and Future Scope of Nanocapsules Market - StartupNG

The Longevity Project Part 1: Medical advancements are keeping people active well past retirement – Steamboat Pilot and Today

STEAMBOAT SPRINGS Eighty-nine-year-old Vanda Nohinek has plans to raft down Cataract Canyon with her 15-year-old grandson next year. With two new hips and a new knee, one might question Nohineks sanity. But fear not she says.

I feel 20 years younger than I am, said Nohinek from her Steamboat Springs townhome. Im as good or better than I was before the replacements.

Medical procedures replacing full hip and knee joints have gotten so sophisticated that even after Nohineks first hip surgery in 2014, she was back on the slopes skiing and out on the road riding bicycles. Then fall 2015 hit, and Nohinek said her right knee went out. Once again, she consulted with Dr. Alex Meininger of the Steamboat Orthopaedic and Spine Institute.

The whole office is just tremendous friendly and uplifting, she said about the group of local surgeons who recently opened a new clinic space and outpatient surgery center, where they anticipate up to 90% of their surgeries will be performed.

Meininger explained that 20 years ago his mentors told surgical residents that knee replacement patients wouldnt likely be skiing or playing tennis again.

Nowadays, I virtually guarantee theyll get back to those things patients enjoy, Meininger said.

Arthritis and joint pain are not a reason to make sacrifices in your life, he added. If you have goals and desires you need to fulfill, then joint replacement is something you should consider.

Meininger cited a number of advancements including artificial joints designed to feel more natural and the sophisticated instruments used to install them more accurately.

Today, we have available new techniques, such as customized instruments and cutting guides based on MRI or CT images, computerized navigation and robotics that allow surgeons to place the joints more perfectly, Meininger explained. I use computerized navigation to identify the axis of the joint and reproduce it precisely within 1% to 2% of the natural knee joint.

After her knee replacement, Nohinek was back on her bicycle, riding through Europe and logging 26-mile marathon rides in Routt County.

So by the time she broke her right hip last fall, the spunky senior seemed almost nonchalant about yet another surgery.

Wasnt worried at all. What good would it do? she laughed.

Nohinek described how quickly patients are up on their feet, usually the same day they come out of surgery.

Physical therapy starts right away, she said.

Nobody knows that better than Marcia Pomietlasz, another active Steamboat resident who was amazed by her two knee replacements in 2013 and 2015, both done by Dr. Meininger.

I was so excited to have the procedure done, said the 72-year-old avid tennis player who suffered from bone-on-bone arthritis in her knee joint. The new knee works right away.

Both women stressed that a positive attitude and consistent rehab, both with the physical therapist and at home, are essential to a full recovery.

Pomietlasz remembers when her own mother had knee surgery back in the 1980s.

It was a whole different ballgame then. She was in the hospital for four days, she said.

Nowadays, its becoming more frequent to go home the following day and in some patients even the same day.

Pomietlasz even noticed the difference between her two knee operations in 2013 and in 2015. She said by 2015, she didnt have to wear a brace after the surgery thanks to new advances in techniques and medications.

Previous anesthetic techniques caused lasting side effects like weakness in the quadriceps muscle, so patients needed a brace so their muscles didnt give way on them, Meininger said.

Meininger said surgeons are now using shorter-acting medications and targeting specific areas or nerves with anesthesia that need it, which leads to less pain and a faster recovery.

Today, Pomietlasz is skiing and playing tennis with ease.

Even my daughter said, you are skiing so much better now that you have new knees, Pomietlasz said. I was favoring one leg over the other. So yes, this is a whole new skiing experience for me.

Both Pomietlasz and Nohinek encourage older people to put away their fears and seek out answers.

How badly do you want your life back? Pomeitlasz asked. Thats what joint replacement can do. It gives you your life back. The technology is so incredible, and it has to have improved in the five years since I had my last surgery.

Meininger said he is also lucky to practice in an active, mountain community with motivated patients.

Results and outcomes are improved when the patient participates in the process, he said. Our patients have higher expectations for themselves, which means more success.

About two years ago, two private orthopedic practices merged to create the Steamboat Orthopaedic and Spine Institute, which is expected to compete with the reputable Vail-based Steadman Clinic. Michael Sisk, Andreas Sauerbrey, Alexander Meininger, Patrick Johnston and Clint Devin are owners of the new medical facility. Additional doctors in the practice include Bryan Bomberg, Adam Wilson, Alejandro Miranda and Lex Tracy.

In North Routt County, Clark residents Jeanne and Dennis Lodwick are shooing their dog away from a visitor. The duo move around briskly, cracking jokes at each other like an old couple in a comedy TV sitcom.

Jeanne got a new hip just three months ago and is back playing pickleball and paddleboarding. Meiningers partner, Dr. Andreas Sauerbrey, operated on Jeannes hip and also put in Dennis new titanium knee two years ago.

But it was another technological advance that changed the Lodwicks lives dramatically.

It was the most amazing medical miracle Ive ever seen in my life, said 74-year-old Jeanne.

She is talking about her husbands neurostimulator, a sort of pacemaker for the brain.

About 15 years ago, doctors diagnosed Dennis with Parkinsons Disease, a brain disorder that leads to shaking, stiffness, difficulty walking and bad balance and coordination. By 2016, the Lodwicks quality of life had plummeted.

I couldnt hold a glass of wine. I literally had to sit on my hands to keep from shaking, Dennis said.

The two couldnt go out in public, because his intense shaking could lead to accidents. The couple even stopped their yearly driving vacations. Then about four years ago, neurologist Dr. Mihaela Alexander gave a talk about advancements in treatment for Parkinsons patients at the Bud Werner Memorial Library in Steamboat.

After hearing about the procedure called deep brain stimulation, the couple made Dennis an appointment with the Denver-based neurologist.

He endured a battery of mental and physical tests before he got the go-ahead to proceed with the innovative procedure.

As the couple scrolled through cellphone photos of all their surgeries, from old bones taken out of Dennis knee, to an X-ray of Jeannes new metal joint, Dennis tried to paint a picture of how the neurosurgeon proceeded.

They basically bolt a robot to your head that helps guide the surgeon, he said.

Dennis hair covers the two large scars where the surgeon implanted the stimulators on each side of his head with probes aimed at a specific site on the brain. Two weeks after they put in the stimulators, they put batteries on each side of his chest and ran wires to the stimulators in his head. Then after two more weeks of healing, the neurosurgeon dialed in the amount of electrical stimulation theyd send to Dennis brain probes.

It was unbelievable, truly a medical miracle, said Jeanne remembering the first time the neurosurgeon turned on the neurostimulators in Dennis brain. He went from shaking all over to nothing. I told the doctor, thats a really good trick. Lets do it again.

We bought five years of quality life so far. I wouldnt have been able to take care of him without it, Jeanne added.

Dennis brought out his small hand-held programming unit to show us how many volts were going to each side of his brain. The part of the brain that controlled the left side of his body showed 2.7 volts, while 3.8 volts was used to control the right side of his body.

My wife keeps joking shell turn it off if I upset her, Dennis joked.

Although Dr. Alexander was unavailable to expound on Dennis treatment, Dr. Drew Kern, a movement disorders neurologist at UCHealth and the University of Colorado, urged people with movement disorders like Parkinsons, epilepsy, dystonia and essential tremor to seek out a full array of medical help.

Deep brain stimulation is one of many advanced treatments available for patients with movement disorders, Kern said. At UCHealth, we have a team approach alongside our patients to determine the best therapeutic approach neurologists, neurosurgeons, physical medicine, rehabilitation physicians, therapists.

He said patient-centered decisions allow people to live as active a lifestyle as possible.

As for the Lodwicks, Vanda Nohinek and Marcia Pomietlasz, they couldnt agree more and they said it all starts with research.

Always get a second opinion, said Jeanne. Any surgery is an important and difficult surgery. Give it a lot of thought, pick your doctor carefully.

And have a positive attitude and expect the best results, Dennis.

Pomietlasz cant imagine that any active senior would think twice about joint replacement.

If youre happy not doing the things you did before, maybe its not for you, she said.

Theres nothing to be scared of, added Nohinek, who moves nothing like an 89-year-old matriarch. Go see your doctor, and if youre a candidate for joint replacement, just go for it.

Frances Hohl is a contributing writer for Steamboat Pilot & Today.

Here is the original post:
The Longevity Project Part 1: Medical advancements are keeping people active well past retirement - Steamboat Pilot and Today

NUS team’s map sheds light on heart diseases – The Straits Times

Researchers have developed a coherent map of genes in the heart and looked at how they may cause heart diseases, which could pave the way for new treatments for these illnesses.

Heart diseases are a complex set of diseases influenced by different genes, and it is challenging to understand which genes are responsible for a particular disease, say experts.

To help scientists unravel the complex web of genes and how they interact, researchers from the National University of Singapore Yong Loo Lin School of Medicine (NUS Medicine) and the National University Hospital created what they said is the first map of the heart's genes and the "switches" between them that control how the genes behave and contribute to heart diseases.

Genes code for specific traits, and the switches are the non-coding portions of DNA between the genes.

Each gene has more than one switch and the switches may be far away from the genes that they control, making it tricky for scientists to match the switches to the genes.

The genetic heart map locates the genes and their switches so that scientists can eventually study them to create targeted treatments, such as gene therapy.

"If we understand how these genes are controlled, then we may find ways to control heart failure itself... and identify new disease-causing genes," said Professor Roger Foo from the university's department of medicine, who led the research team.

Heart diseases, which eventually lead to heart failure, cause one-third of all deaths in Singapore annually.

The researchers are part of the Cardiovascular Disease Translational Research Programme, one of nine new strategic research focus areas that were established at NUS Medicine in July.

The new focus areas, which also include infectious diseases, healthy longevity and precision medicine, aim to create greater synergy and collaboration between basic and clinical scientists within the National University Health System, and to deliver research outcomes that address current clinical and national healthcare issues.

Professor Chng Wee Joo, vice-dean of research at NUS Medicine, said: "We hope that these nine programmes will deliver not just outstanding research, but over the next five to 10 years, make some real impact on how we treat our patients and on the population's health."

BETTER UNDERSTANDING

If we understand how these genes are controlled, then we may find ways to control heart failure itself... and identify new disease-causing genes.

PROFESSOR ROGER FOO, from the National University of Singapore's department of medicine, who led the team that developed the map of genes in the heart.

The development of the gene map was published as two companion publications in the journals Circulation Research and Circulation last month and this month respectively.

The map took about five years to develop, and the researchers studied tissues from 36 healthy hearts and 34 failing hearts to map out the genes and switches.

Prof Foo said some scientists from Singapore and abroad have reached out to them to find out more about various genes from the map.

He also noted that none of the drugs currently used in treating heart disease targets genes, and cardiovascular research is not as well funded compared with other health conditions.

"The place where a lot of gene targeting is happening, I feel, is in cancer. Looking at the progress that cancer treatment has seen in recent years with targeted therapy, this is our dream for cardiovascular disease also, now that we have mapped out all these specific processes," he added.

Follow this link:
NUS team's map sheds light on heart diseases - The Straits Times

The Benefits of CrossFit for People Age 60 and Above – BarBend

Its never too late to start.

Age is just a number.

These age old (no pun intended) adages are passed around a lot in the fitness community. Although often only meant as a means of inspiration, they may have a lot of truth to them as well, scientifically speaking. When it comes to improving physical and mental health, longevity, and quality of life, fitnessmight be one of the best means to do so. So we decided to do a deep dive on how and why CrossFit training can be a valuable fitness option for people over the age of 60.

Below are some of the major topics we cover:

In addition to better educating about how CrossFittraining can help build a stronger body, mind, and community, this article aims to be a go-to reference for common exercisesand how to get involved in competitive events.

Editors note: The content on BarBend is meant to be informative in nature, but it shouldnt take the place of advice and/or supervision from a medical professional. The opinions and articles on this site are not intended for use as diagnosis, prevention, and/or treatment of health problems. Speak with your physician if you have any concerns and before starting any new dietary or training regimen.

[Related: The ultimate guide to strength sports for Masters athletes]

Functional fitness is a classification of training that incorporates movements akin to what a person would perform in their day-to-day life. This can include squats, lunges, jumps, pulling movements, and cardio (running, biking, etc.). CrossFitmethodology adds in Olympic weightlifting (snatches and clean & jerks), powerlifting (deadlifts, front and back squats), explosive movements (using medicine balls, kettlebells, etc.), gymnastics, and some specialized movements such as rope climbs, sled work, and rowing.

There are many potential health benefits, so lets dive into what it can specifically offer athletes over the age of 60.

It is important to note the culture of support around the CrossFitcommunity. It is one of the most important means for acquiring new members as well as maintain those who have already been initiated. According to a 2018 systematic review and meta-analysis in theSports Medicine Open, preliminary data has suggested that CrossFit practice is associated with higher levels of sense of community, satisfaction, and motivation. (1)

It is likely the case that one of the biggest draws for anyone thinking of getting into CrossFittraining is improving longevity while maintaining or bettering physical capability. The evidence showing correlations between endurance training, high intensity interval training (HIIT), and high intensity functional training (HIFT) and longevity is pretty extensive.

Fifty-four peer-reviewed publications found considerable support for superior longevity for people involved in endurance related sport. (2) More specifically, a study in the Journal of Aging Research determined a physically active subjects had a higher life expectancy of upwards of 7 years.

A 2013 study in Population Health Managementrecognized that a critical need for senior-oriented programs that improve health and preserve and extend functional capabilities. The relationship between these improvements also led to reduced health care expenditures. (3)

For those who have not had a consistent training program, the intensity that comes along with CrossFit training might be intimidating. Dont worry, there are ways that new trainees can perform workouts without extending past their abilities or what is comfortable for them. One of the major ways is called scaling (more on this later).

Rest assured that the science is behind getting active to improve physical fitness even in the elderly. Progressive strength training in the elderly is an efficient wayto reduce sarcopenia and retain motor function, even at higher intensities, according to a 2011 study in theDeutsches Arzteblatt International.(4)

Furthermore, anyone who may be skeptical about the safety of higher intensity exercise, HIFT is not necessarily any riskier than any other form of exercise at a relatively equal intensity. A 4-year analysis that oversaw3,049 participants completed in 2018 in the Orthopedic Journal of Sports Medicinesuggested that CrossFit training is relatively safe compared with more traditional training modalities. (5)

Not only is getting physically active a smart choice for overall fitness levels, it might actually be better to train more days per week than less. That same 4-year analysis uncovered training for the majority of days per week could lead to fewer injuries. Those at the greatest risk of injury, primarily to their shoulders and back, were the participants who performed less than 3 workouts per week.

For athletes over the age of 60 participating in CrossFittraining for the first time, there should be some comfort knowing that the risk of injuryis similarto other sports according to a 2020 study in theJournal of Human Kinetics.(6) To further reduce the risk of injury, athletes are better off doing an adaptation period with the aim of improving technique. Good news:improving technique is a touchstone of CrossFit methodology.

Technique, which is defined in theCrossFitlevel 1 training guide as quality of movement, isan intimate part of safety, efficacy, and efficiency. Technique is everything. It is at the heart of our quantification. You will not express power in significant measure without technique.

So how does CrossFittraining adjust for those who have never done it before? They do so through scaling.

Scaling is the process of adjusting a workout or movement to better match the abilities of the person performing it. It is also a way to customize training for a persons needs at any given time. Feeling sore from a previous training session? Scale the workout. Feeling some tenderness in a muscle or joint and are concerned about aggravating it? Scale the workout.

Scaling is very important when learning a new lifting pattern. If someone has never performed a particular movement, it doesnt make much sense to load up a ton of weight and hope for the best. Remembering the importance of technique regardless of age or fitness level is key. CrossFit trainers are generally eager to work with clients to find the right movement patterns for their needs and goals.

As the trainee who will be performing the exercises, be sure to clearly articulate your goals. They can be as simple as wanting to walk up the stairs more efficiently or picking things off the ground without causing back pain. Scaling allows the trainer and the training itself to help further you toward whatever your goals may be.

Training in a group environment makes participants more motivated and more reliable the longer they do it. A 2019 study in thePLoS One(the Public Library of Science) looked into how motives differ by length of participation. They concluded that the enjoyment and challenge of HIFT was a sufficient motivator when beginning, and that this exercise form promotes an increase in those motives with greater length of participation.

The study also concluded that interpersonal motives (representing relatedness) also increase with participation time. (7) A 2017 study inBMJ Open Sport and Exercise Medicine furtherreinforces these ideas with their findings that group exercise helps participants meet recommended levels of physical activity. (8)

The community aspect of CrossFit enables a higher likelihood that people will exercise and enjoy it the more they do it. A2017 study inBMC Geriatrics concluded thatregular group exercise contributes to balanced health in older adultsand helped them to improve or maintain their functional health and enjoy their lives.(9)

There may be concerns for those above the age of 60 to get involved in any sort of group fitness. However, there are strong arguments to be made about ensuring exercise remains a part of the routine for seniors. In a 2018 study inFrontiers in Immunologythat analyzed exercise-induced immune suppression, scientists found thatleading a physically active lifestyle reduces the incidence of communicable (e.g., bacterial and viral infections) and non-communicable diseases (e.g., cancer), implying that immune competency is enhanced by regular exercise bouts.

They concluded that that leading an active lifestyle is likely to be beneficial, rather than detrimental, to immune function, which may have implications for health and disease in older age. (10)

Exercise has shown to aid other issues such as peripheral arterial diseaseand helpssuppress the most common age-associated chronic conditions.(11)In a 2015 study in Rejuvenation Research, scientists found that physical exercise islargely the answer to attenuate many of its deleterious systemic and cellular effects. (12)

Functional fitness training has potential benefits for physical and mental health, and longevity. But how and where does one sign up?

If youre interested in joining a CrossFit affiliate, youre in luck; as of early 2020, there are14,790 totalCrossFit affiliates globally.You can start by checking out theOfficial CrossFit Affiliate Mapthat can help locate the nearest CrossFit boxes near you.

When beginning, a coach will teach how to do the movements properly and adjust them as needed for your current fitness level (scaling!). CrossFit.com has quick tutorials that break down the movements so they can be practiced from home. There are also courses that anyone seeking to improve their health and fitness through effective training and nutritional strategies can take.

Here is a list of guides for the non-bodyweight movements you are likely to encounter that you can refer to:

Here is a list of guides for bodyweight movements:

If you are ever in a position where you dont have access to the requisite equipment, scale it and/or check out our CrossFitters guide to movement substitutions.

[Related: 8 things I wish Id known before starting CrossFit]

Whether youre just starting out in CrossFittraining or are actively looking to compete, being aware or even knowledgable about higher levels of competition cant hurt. It might even provide a means of inspiration. Here is a quick rundown of the pinnacle of CrossFit competition The CrossFit Games and how athletes get there.

It takes place once per year, is broadcast and live-streamed internationally, and features individual, team, and age group competition (teens and Masters divisions). There are four main ways to qualify for the CrossFit Games: Open, Sanctionals, Online Qualifiers, and Invitations.

The Open is a worldwide event that spans five weeks. Each week, a workout is released and participants are allotted four days to record their performance and submit it for review. Upon completion of the Open, the top ranked man and woman using a relative scoring system from each participating country is declared national champion(based on citizenship) and is offered an invite to the Games. In addition to the national champions, the top 20 men and women in the Open worldwide also receive invites.

Athletes results for each workout and their respective rankings are tracked via the CrossFit leaderboard. Leaderboards can be customized to highlight members of a group, profession, location, etc. so even if you dont have interest in higher competition, you can see how you stack up against a particular group.

According to CrossFits website,Sanctionals are independently owned and operated (and CrossFit-licensed) fitness competitions that offer another pathway for top men, women, and team athletes to receive invitations to compete at the CrossFit Games.

There were 28 Sanctionals planned around the globe that fed into the 2020 Reebok CrossFit Games. 26 teams (each comprised of 2 men and 2 women), 40 teens, and 120 Masters athletes are invited to the Games under the current format.

In competitive CrossFit, there are six Masters divisions that each span 4 years starting at age 35 up to the age 60+ division.Jarka GiangiulioandPatricia McGillare age 60 and 61, respectively, and are both CrossFit Games athletes.72-year-oldLaura Bruzzonedid not get started in the sport until age 67 and has some valuable advice to offer others who are considering doing the same.Below are their thoughts on CrossFit including their introductions to the sport and what motivates them to continue training.

Giangiulio achieved her firstmuscle-upat age 60 and is capable of deadlifting 285lb. She spent the first half of her life in Slovakia and has since been in the United States and trains atCrossFit Parallax in New Jersey. She placed seventh in the womens 60+ division in the CrossFit Games Age Group Online Qualifier to earn a spot at the 2020 Reebok CrossFit Games.

She started CrossFit in 2011 after getting her fitness in via aerobics, spin, and bootcamp classes. When asked what drives her to compete, Giangiulio responded:

theres this rush when you compete, and that feeling you get when you finish and you know you did well, its amazing. Its hard to explain. But its just good energy, and everyone is supporting you and cheering for you.

Another big draw to CrossFit is the efficiency of the training.

with CrossFit, theres always room for improvement, always something you can work on. I really like that. And I like that in just seven minutes, you can get a really hard workout and be done with it.

McGill began training CrossFit in 2013 and was the runner-up at the 2019 Reebok CrossFit Games in the 60+ division. She then followed it up with a 3rd place finish in theCrossFit Games Age Group Online Qualifier last fall. She trains six days a week and even performs workouts in her backyard.

I said to my husband, Honey, if I dig a hole, will you cement a pole so I can practice muscle-ups?

She splits her training between home workouts and sessions at the gym. Her basement is set up with kettlebells, dumbbells, a rowing machine, and the requisite Olympic weightlifting equipment. Her backyard is outfitted with a rope for climbs, a step for wall balls, and the aforementioned pole to support rings to allow for pull-ups and muscle-ups.

When asked what keeps her motivated to train into her 60s, McGill responded:

I just want to be able to continue to do whatever I want for the rest of my life.

The 72-year-old Bruzzone took up CrossFit five years ago after it was recommended to her by a friend. In her interview withGood Morning America, Bruzzone shared some advice for potential fellow Masters athletes:

You certainly shouldnt let age or anything else hold you back. So long as you dont give up and you do something, youre going to get payback, definitely.

Bruzzones training sessions and feats of strength in a CrossFit gym went viral as a means of inspiration for younger athletes. However, Bruzzone found the opposite to be true as she feels younger athletes inspire her:

I see the younger people doing heavier weights and I want to get closer to what theyre doing. Its more motivation for me to push harder.

Although Bruzzone has never competed in the CrossFit Open or at the Games, she still trains at 6am on most days, and only takes a rest day when she feels it necessary. Her fitness goals are positioned to thinklong term.

I have a long range plan. When Im 90, I want to get to the bathroom by myself.

We reached out to two doctors of physical therapy, Dr. Joseph LaVacca and Dr. Eugene Bo Babenko who is also a certified CrossFit trainer. They discussed the benefits and obstacles (both physical and mental), the remedies to those obstacles, personal experiences theyve had with their patients, and advice they would offer those starting out in functional fitness training.

Note: all bolding is done by BarBends editorial team for emphasis.

Functional fitness is the key here YES the way we think about aging is all sorts of messed up.If seniors, or any human of any age, want to be able to use their bodies, then they need to do some type of training to maintain it just like we do maintenance on our cars. While there is a natural degradation that comes with each day/month/year, it is all about managing that damage that allows us to improve healthspan, which implies the ability to be a more robust human for longer. If folks want to live longer and be able to do more things, then they 100% should participate in some kind of training program or movement practice.

Yes, without a doubt.Seniors biggest opportunity as they age is the loss of muscle mass, mainly power, and a narrowing social circle which is actually the number one factor for most of their stress and ailments. CrossFitis the perfect solution to both given classes are guided by coaches who understand the aging process and can be scaled accordingly to fit the capacity of each client.

More and more we are seeing research support the idea that we are not our x-rays or MRIs and a lot of the dysfunction we see with these images can sometimes be nothing more than normal age related changes our bodies go through as we continue to use them.

General de-conditioning is the number one overall ailment many of the cliches come to mind. Do we age because we stop dancing, or do we stop dancing because we get old? You are only as old as your joints feel.

The most common things that put folks in retirement homes or the morgue are a fall and broken hip the best way to combat this is to improve range of motion, proprioception, and strength. Leg strength, grip strength, and VO2 max are all incredible predictors of our mortality and can all be improved with functional training.

[CrossFit] also recently had a huge push for CrossFit Health, where they had seniors as the demo folks in a living room, using water bottles and such this is a great message and speaks to the fact that we all need to be partaking in some version of fitness for our entire lives and the barrier to entry should be very low.

As we age we are typically met with increasing co-morbidities such as weight gain, mental health issues, and changes to our cardiovascular systems (blood pressure/heart rate). I think community outreach and education can be an affective remedy.This population has survived and thrived through a lot of stress and changes in their lives. They very rarely want to be thought of as delicate, old or fragile. Holding 60+ classes to make people fit into a more common group of people, educating primary care physicianson the benefits of exercise as we age.

Aside from reduction in depression, anxiety and improved sleep, exercise has been shown to add years to your life, something that we can all likely agree is the ultimate benefit.

The biggest obstacle is fear/marketing it looks scary usually these CrossFit gyms have only young folks with shirts off huffing and puffing and making very loud noises of all sorts.

Culture seems to be the biggest obstacle for just about everything these days. When you are told that aging population is fragile, or should stop doing certain movements/exercises, or that their joints are bone on bone, those are the kind of thought viruses that spread very quickly,usually promoting fear and avoidance rather than reframing and lateralization.

Most effective remedies I have seen are specific silver sneakers programs specific marketing to get folks to see others in their age range can and are doingthis, and not getting injured. Sometimes its important to connect it to activities that are importantto that population.

I think community outreach and education can be an affective remedy. This population has survived and thrived through a lot of stress and changes in their lives. They very rarely want to be thought of as delicate, old or fragile. Holding 60+ classes to make people fit into a more common group of people, educating primary care physicianson the benefits of exercise as we age. Aside from reduction in depression, anxiety and improved sleep, exercise has been shown to add years to your life, something that we can all likely agree is the ultimate benefit.

Biggest benefits for CrossFit seem to be the increased ability to do the activities that we hold dear and overcome many of the aches and pains that we have built up over time. Another thing that works is one-on-one training with very personalized progressions.It is easier to throw constantly varied workouts at younger folks but as we develop more limitations we require more personalized attention to get better results and avoid injury.

These patients have more lean body mass, recover from injuries quicker, usually have jobs that they find more satisfying, are on little to no medications, and most important can envision their future and can continue to create goals both personally and professionally. One thing that happens as clients get older, retire, watch their kids grow is that they lose a sense of purpose. Those that maintain and active mind and body experience the same stressors but demonstrate more resilience when facing them.

Absolutely, I have worked with a number of folks above 60. Their performance far exceeds anyone in their cohort who does not. They are addressing so many physical factors.I also work as a home health physical therapist and I have seen everything from COVID pneumonia cases, stroke cases, etc., and no matter the age and function, I utilize many of the principles of CrossFit for my patients to help them improve and address their various impairments.

One thing that happens as clients get older, retire, and watch their kids grow is that they lose a sense of purpose. Those that maintain an active mind and body experience the same stressors but demonstrate more resilience when facing them.

Socialization hands down.The communities I have watched grow, and the friendships formed, allows for people to cheer for each other because they truly want what is in the best interest of the other person. CrossFit communities plan nights out, go to each others weddings, and even spend holidays together. As the gym grows, so does your family.

I would want to make sure they understand what the term CrossFit refers to. I would want them to be an educated consumer and ensure that thecoach/trainer they work with has some experience with similar pops and/or is able to provide them with a personalized plan to keep them safe and still reaping the benefits that the community setting brings.

That is great and I am proud of their decision. I would encourage them to look at their goals:

I would further suggest having a personal trainer that can work with their coach on your team. Where I think the biggest opportunity for community classes of all sorts to continue to evolve is providing information and understanding about each members individual capacity.

I think the concept is phenomenal. Ifell in love with it when I did my first workout and then did the CrossFit Level 1 certification. But since I entered the community in 2010, I have seen many versions of the original message create many watered down versions. It is going through some interesting changes withGlassmanselling the company. It will be interesting to see how it progresses.

In general I have been a huge fan and advocate for CrossFit since I began my career in 2010. Unfortunately the average career of a HIIT or CrossFit athlete (based on memberships) seems to be less than 3 years. This was presented at a Sports Symposium in Philadelphia not too long ago that I was able to attend.

This is the biggest opportunity for HIIT classes. Build consistency. The community is there, but people are scared and think this is not for me or I could never do that. Everyone is waiting to feel better to move or workout, rather than working out to feel better.

In addition, sometimes culture leads us to believe that we need to be emptying the tank all the time. That we need to be pouring sweat, not have an off day, or complete an insane challenge that we are not ready for to fit in. I would love to see more scaling to keep people safe, not just an RX and an alternative with less weight or reps something meaningful where this group can look at each other and say I am here and I am with other people just like me, and I do not have to be forced to do what is on the board.

I do believe that if every gym followed a CrossFit type model in a responsible manner, the world would be a healthier and stronger place.

The science is clear.CrossFittraining can enable people over the age of 60 the ability toimprove their physical fitness, their ability to day-to-day activities more efficiently, and their ability to prevent disease.It can offer a supportive community that can better ensure consistency in the gym and make workouts more enjoyable.

For those above 60 years of age looking to improve their futures, CrossFittrainings focus on individual goals and proper technique might be the way to go. There are CrossFitaffiliates are all over the world that can help you get a foothold in that community and build your body for many years to come.

Brent Hamar, et al. (2013). Impact of a Senior Fitness Program on Measures of Physical and Emotional Health and Functioning.Population Health Management.16(6): 364372.doi:10.1089/pop.2012.0111.

Allyson G. Box, et al. (2019). High Intensity Functional Training (HIFT) and competitions: How motives differ by length of participation.PLoS One.doi:10.1371/journal.pone.0213812.

Komatsu, H., Yagasaki, K., Saito, Y.et al.Regular group exercise contributes to balanced health in older adults in Japan: a qualitative study.BMC Geriatrics17,190 (2017). doi.org/10.1186/s12877-017-0584-3.

Tara L. Haas, et al. (2012). Exercise Training and Peripheral Arterial Disease.Comprehensive Physiology.2933-3017.doi:10.1002/cphy.c110065.

Feature image via Shutterstock/Halfpoint.

Link:
The Benefits of CrossFit for People Age 60 and Above - BarBend

Six pivotal moments of the 2015 ‘migrant crisis’ – InfoMigrants

A tragic shipwreck in the Mediterranean, a lifeless boy on a beach, the fickleness of politicians, borders opening and shutting -- these are some of the enduring images of the summer and fall 2015 in Europe in the context of migration. We look at six pivotal moments that have defined the so-called migrant crisis and have been engraved in our collective memory.

On the night of April 18, 2015, a small blue trawler coming from Libya capsizes and sinks in the Strait of Sicily under the horrified eyes of the crew of the "King Jacob", a Portuguese freighter sent to help.

Only some 30 survive among the more than 800 migrants who had been crammed on board the trawler. The tragedy, likely caused by overcrowding and incorrect maneuvers, is one of the worst in recent decades in the Mediterranean.

The scale of the disaster and the chilling accounts of survivors provoke a wave of outrage and push the European Union to strengthen its presence off the Libyan coast. In 2016, an Italian court sentences the Tunisian captain of the trawler to 18 years in jail.

In March of this year, UN migration agency IOM estimates that the death toll of migrants who had tried to cross the Mediterranean Sea since 2014 has passed the "grim milestone" of 20,000 deaths.

Wearing a red T-shirt and blue shorts, the small lifeless body of a three-year-old Syrian boy lies on a Turkish beach. He drowned with at least four other people, including his mother, his five-year-old brother and two others on their rubber boat as they tried to reach a Greek island.

Theheartbreaking photographs of the toddler's body washed ashore in Turkey quicklymake global headlines, prompting international responses and sparking aflurry of donations for asylum seekers. Alan Kurdis death also becomes aglobal symbol of the plight of refugees at sea.

"It was as though themigrants' crisis, so often told through numbers, had found a human face,"news agency AFP wrote.

In total, more than a million people reach Europe via the sea in the year of 2015. Among them, more than 850,000 arrive on Greek shores, the majority are Syrians fleeing their war-torn country.

In 2019, German NGO Sea-Eyenamed its search and rescue (SAR) vessel Alan Kurdiafter the Syrian boy. It has since helped save thousands of lives in the central Mediterranean.

In March this year, a Turkish court sentenced three suspects to 125 years in prison each for the death of Alan Kurdi.

At dawn on August 15, 2015, German photographer Daniel Etter is waiting on the shores of Kos, a Greek island in the Aegean Sea mere kilometers away from mainland Turkey. Soon, a family arrives on the island on a sinking boat.

"Locals, who were there that morning, pulled them on the beach," Etter wrote on Twitter last month. "A visibly shaken man left the boat. As soon as he reached safety, his emotions took over and he gathered his family around him."

That man was Iraqi Laith Majid. In September 2015, it was discovered that the family was actually from Iraq, not Syria as initially reported. "Given the hierarchy imposed on refugees back then, their smuggler told them to pose for Syrian," Etter said.

The photograph was part of the New York Times entry that won the 2016 Pulitzer Prize in the Breaking News Photography category.

It's August 31, 2015. After visiting a camp for newly arrived refugees, German chancellor Angela Merkel attends a press conference, where she utters a simple sentence about taking in refugees that is now famous: "Wir schaffen das!" ("We will manage this!").

Merkel was addressing the fact that hundreds of thousands of refugees were expected to reach Germany that year.

Fearing a humanitarian crisis, she soon after took a stand and announced an open-door policy. Her decision is a landmark moment. In the year that follows, more than a million people claim asylum in Germany.

Dubbed "Mama Merkel", the chancellor is hailed by Syrian asylum seekers and praised by those who believe she has saved Europe's honor. But her decision also provokes a backlash in Germany and other European countries and helps to give rise to far-right parties including the Alternative for Germany (AfD).

Since 2015, the number of asylum applications has fallen steadily, with Syria remaining the main country of origin for asylum seekers and refugees in Germany.

Today, Germany is the country with the fifth highest refugee population worldwide, according to UN refugee agency UNHCR. By the end of 2019, there were 1.36 million people with protection status in Germany

Between 2015 and 2020, the German government took many steps to reduce the number of asylum seekers, including new laws that made getting asylum more difficult like supporting the EU-Turkey deal.

While many of them are still struggling, the overall trend for refugees and migrants in Germany is positive: 10% more refugees are employed today than in 2015.

Some 20 Eritreans, smiling under the flashes of photographers' cameras, board a plane in Rome. It's October 9, 2015. The men and women, rescued off the Libyan coast and taken to Italy, are now headed for Sweden.

The transfer initiates a "contentious European Union relocation program meant to help the union's front-line countries deal with the largest movement of refugees on the Continent since World War II," the New York Times writes pithily that day.

Italy and Greece are the first entry points into the then-28-nation bloc for hundreds of thousands of people fleeing war and poverty in Africa, the Middle East and Asia.

At the airport send-off ceremony, Italian and EU politicians proudly repeat that in the next two years, 40,000 refugees from Eritrea, Iraq and Syria would be resettled from Italy throughout member state countries, helping share Italy's burden.

Two months later, the result is meager. A mere 133 people of the 40,000 were relocated from Italy. Some countries drag their feet, others such as Poland and Hungary refuse to carry it out, despite its being compulsory.

In September 2015, a month before the scene at the Rome airport, European countries agree to a "relocation" plan to redistribute some 160,000 asylum seekers from the bloc's two main points of entry by September 2017. After officials found that fewer people were eligible under the scheme that first expected, the number was later revised to just under 100,000.

Ultimately, though, only 33,000 took part in the scheme across EU member states. "The plan, supposed to embody Europe's solidarity, becomes a symbol of division," AFP wrote.

As hundreds of thousands of migrants come into Europe in 2015, one of the most common ways for them to arrive in the EU is through the so-called Balkan route. Their path typically begins in Turkey and then wound through either Bulgaria or Greece. The migrants then make their way further north, eventually reaching Slovenia or Hungary on the path towards countries like Germany.

As spring 2016 approaches, however, the situation changes radically. Countries along the route, from Macedonia, to Croatia and Slovenia all the way to Austria, where a corridor allowing migrants to pass had been in place since summer 2015, all announce that their borders are shut. However, refugees frustrated by the closing of borders still manage to go along the route.

And on March 18, the European Union and Ankara reached a controversial accord ("EU-Turkey deal") to address "irregular migration" from Turkey into the European Union. Under the agreement, Turkey would be obligated to take back migrants who pass through its territory to prevent them from crossing into Greece illegally.

For every "irregular" migrant returned to Turkey, another migrant approved for asylum in the EU would be resettled in one of the bloc's 28 member states. In addition, the EU gave Turkey 6 billion ($6.6 billion) in financial aid to assist with the country's large refugee population, which is currently above 3.5 million.

Between 2016 and March 2020, Germany accepted almost 10,000 migrants and asylum seekers under the accord.

The outcome is a drastic drop in the number of arrivals in Europe, but tens of thousands of migrants find themselves stranded in Greece, raising fears of a humanitarian crisis and Erdogan using their situation for political gain. And Europeans remain divided over key refugee and asylum policies. Numerous initiatives such as a binding distribution quota for migrants have failed.

This article is based on a feature from AFP.

Continued here:

Six pivotal moments of the 2015 'migrant crisis' - InfoMigrants

Europe’s migrant crisis is worsening during the pandemic. The reaction has been brutal – CNN

Coronavirus has left countries such as Tunisia facing serious economic hardship and unemployment, while others, including Libya, are dealing with the effects of war. That's led to an increase in sea arrivals this year in countries including Italy and Malta, according to figures from the United Nations High Commissioner for Refugees (UNHCR). Arrivals in southeastern Europe are also up on 2019, mostly from Syria, followed by Morocco and Iraq.

But European responses have often been brutal. Humanitarian organizations say pushbacks at borders in countries such as Greece, an absence of sea rescues in the Mediterranean and unhealthy quarantine arrangements have created huge challenges. And it comes at a time when movement is harder and more dangerous thanks to travel restrictions and the closure of transport routes and processing centers.

Last week, a man was found dead on Sangatte beach, near Calais in northern France. He and a friend had tried to cross the English Channel, one of the world's busiest shipping lanes, in an inflatable dinghy with shovels for paddles. The friend said he was just 16, but French authorities said his papers belonged to a 28-year-old Sudanese migrant and an autopsy showed he was an adult. He couldn't swim, his companion said.

UK Home Secretary Priti Patel said the "tragic loss" was "a brutal reminder of the abhorrent criminal gangs and people smugglers who exploit vulnerable people."

The news came on the same day that at least 45 migrants perished in the deadliest recorded shipwreck off the Libyan coast this year, according to the UNHCR and International Organization for Migration (IOM).

The organizations said there was "an urgent need to strengthen the current search and rescue capacity."

"Delays recorded in recent months, and failure to assist, are unacceptable and put lives at avoidable risk," they added.

Journeys in a pandemic

Almost 4,900 people have crossed the Channel in small boats since lockdown began, more than double the amount thought to have crossed in the whole of 2019, according to analysis by PA Media.

"We know that smugglers and traffickers have obviously been impacted by the pandemic and the restrictions that were put in place. But we also know they're very adaptable," UNHCR spokesman Charlie Yaxley told CNN.

"That's a big concern for us because it also means that the refugees and migrants who are taking these journeys are taking more dangerous and more risky routes."

He said migrants were facing torture, rape and other abuse during land journeys to Libya "by smugglers, traffickers, militias, but also state officials."

Yaxley said there were currently no rescue ships on the central Mediterranean, or EU programs as in previous years, so migrants leaving Libya by boat were often taken back to Libya by the coastguard to face detention or other rights violations.

But the response from European countries burdened by coronavirus has been icy, with migrants forced back or detained in overcrowded, unsanitary conditions.

Felix Weiss, from the German NGO Sea Watch, told CNN he understood the anger from businesses already struggling during the pandemic.

"But this is stuff that you could definitely avoid," he said. "Just disembark them, and then find a solution where they can go in Europe.

"There has to be a European solution," he added. "This is a European failure."

'Nightmare' situation

Weiss said conducting rescues had become "a nightmare" during lockdown because of countries including Italy and Malta blocking boats and refusing to act themselves.

Officials say migrants should quarantine for 14 days on ferries, but some have been kept on unsuitable pleasure boats or oil tankers. Migrants with health issues who have endured detention in inhumane conditions have been stranded for up to six weeks, said Weiss.

"People are traumatized," said Weiss. "The Ocean Viking can take persons for a few days ... but we [rescuers] are not trained to have really bad psychological cases."

Italy's Interior Minister Luciana Lamorgese said at a news conference on August 15 that families facing economic crisis in Tunisia were "leaving in search of better life conditions."

"Managing the migrants' flow has been more difficult due to Covid emergency," Lamorgese added.

HRW said several asylum-seekers reported being picked up from Greek islands by the coastguard, forced onto inflatable rafts with no motor, and cast adrift near the border.

"Instead of protecting the most vulnerable people in this time of global crisis, Greek authorities have targeted them in total breach of the right to seek asylum and in disregard for their health," said Eva Cosse, Greece researcher at HRW.

Europe's responsibility

Many migrant camps and centers pose a major risk for the spread of coronavirus.

On July 30, 129 migrants tested positive for Covid-19 at a camp in Treviso, in Italy's Veneto region. Lampedusa's 90-person capacity camp currently has 1,300 residents, according to Weiss.

After more than 200 migrants ran away from a camp in Sicily last month, the region's governor Nello Musumeci warned in a statement of an "unsustainable situation," saying "the issue of migrants has also become a matter of public order and health."

It said that during lockdown, "inequality has been sharpened for transit communities, further limiting access to asylum, healthcare, adequate accommodation, and safety from brutal collective expulsions."

Yaxley said the situation was still "very manageable," but there needed to be "EU solidarity with those Mediterranean coastal states through relocation programs ... so that there's a sharing of the distribution of the responsibility."

"The ad-hoc approach simply inflames the toxic political narrative," he said.

"There's a real need for compassion and humanity."

CORRECTION: An earlier version of this story misstated which NGO operates Ocean Viking. The vessel is run by SOS Mediterranee.

CNN's Livia Borghese, Valentina Di Donato, Martin Goillandeau, Alexander Durie and Eva Tapiero contributed to this report.

Read this article:

Europe's migrant crisis is worsening during the pandemic. The reaction has been brutal - CNN

Five years since the European migrant crisis, Balkans route still a hope for migrants – Deccan Herald

With a smart black sweater and a clean-shaven face, Younes Qermoua recalls his first attempt to reach Europe five years ago, at the peak of the continent's refugee crisis.

Half a decade later, the world's attention has moved on but the 35-year-old Moroccan is back on the Balkan route, where traffic is picking up this summer even amid the coronavirus pandemic.

After years of bouncing back and forth across the region in attempts by boat, on foot and even tucked above the wheel of a truck, Qermoua's goal remains unchanged.

"I want to live in a country where I can work and get paid for my work, a country where the laws are respected, where there are hospitals, schools," he told AFP in a migrant centre outside Sarajevo, where he is catching some rest before continuing westward towards EU member Croatia.

In 2015, hundreds of thousands of migrants and refugees traversed the Balkans in weary columns, reaching the peninsula through Greece before trundling northwards.

The route was officially shut down under a 2016 deal between Brussels and Turkey.

But in reality, the movement has never stopped.

While the numbers are lower, tens of thousands still flow through the region annually, escaping war and poverty in Asia, the Middle East and North Africa.

Qermoua, who in his first attempt never made it past Greece, is now making progress on a new route that bends west through Bosnia to avoid tighter controls in Hungary, which built a border fence in 2015.

He joins a summer surge of travellers in the Balkans who are on the move after the loosening in early spring of virus lockdowns, when movement was curtailed and some migrant camps were sealed shut.

In June, the Western Balkans was the most active migratory route into Europe, while the first six months of 2020 saw a 73-percent increase in migrants detected at the borders compared to the same period last year, according to Frontex, the EU's border police.

For Lence Zdravkin, whose front porch looks out onto a railway track slicing through the centre of North Macedonia, there is a sense of deja vu.

When huge numbers of people started passing her doorstep during the crisis five years ago -- following the train tracks as a guide -- she became a local hero for collecting food, clothing and other donated aid for them.

This summer, the 53-year-old sits on her balcony with a bright light to help spot travellers who are again passing regularly, though fewer donations are coming in as the world's attention is focused on the pandemic.

"The refugees are facing the same sufferings, with the same journeys, with all the problems that accompany them from the beginning of their travel to its end," she told AFP.

The warm months always bring a new tide of migrants but this summer the numbers have "drastically increased", she said.

While North Macedonia built a barrier on its southern border with Greece in 2015, migrants can still slip in through a mountainous region where the barrier doesn't reach, said Jasmin Redjepi, from the Skopje-based NGO Legis.

Many then take the railway tracks, often hopping onto the links between the carriages of freight trains barrelling past.

According to data from the UN's refugee agency, arrivals in North Macedonia over the past six months have already topped last year's figures for the same period, reaching nearly 23,000.

"They want to cross during this period and get to Europe because they do not want to find themselves in autumn and winter with closed borders and quarantines again," Redjepi told AFP.

Some stretches of the Balkan route are more complicated than they were five years ago, with migrants forced to cross difficult terrain to avoid border barriers and boosted patrols.

Reports of violent pushbacks at the frontiers have also become commonplace, with migrants describing beatings, theft and other abuse at the hands of police.

After crossing Turkey's land border with Greece, Qermoua walked some 700 kilometres (435 miles), mostly alone he says to avoid detection, through Albania and Montenegro to reach Bosnia.

But the next leg of his journey may be even tougher as the country's northwest -- which flanks the border with Croatia -- once again becomes a dead end.

Local authorities have started blocking the entry of new arrivals to the region, where official camps are filling up and thousands of more migrants are sleeping rough in abandoned homes and factories.

While locals were initially receptive to the foreigners, some are now protesting against the influx, calling on authorities to "clear" the streets.

Local mobs have recently stopped buses and pulled off migrants and asylum seekers, leaving them stranded.

The mood has also soured in Serbia, where right-wing groups have become more vocally anti-migrant in recent years.

In a park near Belgrade's bus station, scores of foreigners gather on the grass, a common meeting point to link up with smugglers.

Many bear the same wounds from thwarted attempts to cross the Croatian, Hungarian or Romanian borders: gashes on their lower legs and smashed mobile phones they attribute to violent police expulsions.

After five years stuck in the Balkans, Arif, a soft-spoken 24-year-old from Pakistan, is one of those whose hope is fading.

"My mother and father keep calling me to come back home, and now I tell them, as soon as I get my papers, I'll be back".

Link:

Five years since the European migrant crisis, Balkans route still a hope for migrants - Deccan Herald

Migrant crisis: Five years after refugee influx, Merkel ‘would do the same’ – RTL Today

Five years after Germany controversially took in hundreds of thousands of migrants, Chancellor Angela Merkel said Friday she would do the same again as she rides a wave of popularity for her handling of the coronavirus pandemic.

"I would make essentially the same decisions," Merkel said at her annual summer press conference in Berlin, in response to a question about whether she regretted her 2015 policy to keep the border open to an influx of asylum seekers.

"When people are standing at the German-Austrian border or the Hungarian-Austrian border, they have to be treated like human beings," she said.

More than one million people filed asylum applications in Germany in 2015-2016 during a pivotal moment in Merkel's now 15-year tenure.

The influx deeply polarised Germany and fuelled the rise of the far-right AfD party, weakening Merkel's standing at home.

But as the veteran leader, 66, nears the end of her fourth term, her handling of the coronavirus pandemic has given her an unexpected popularity boost.

In a recent Infratest Dimap poll, 71 percent of respondents said they were very satisfied or satisfied with Merkel's work.

The AfD, on the other hand, has seen its ratings decline during the pandemic.

"It's amazing to see how quickly things can change," notes Hans Vorlaender, a professor of politics at the TU Dresden university. "As a rule, crises are always a make or break moment for those in charge."

Voters have been charmed by Merkel's "rationality, calmness and self-confidence" during the crisis, he observes.

Her understated pleas to the German public to help fight the virus were well received because they were "not a macho show of power, but filled with empathy", he said.

- 'Loss of control' -

Back at the height of the migrant crisis in 2015, Merkel at first seemed to have public opinion on her side, taking smiling selfies with the new arrivals and coining the now legendary phrase "We can do this!"

But the debate around migration became deeply divisive, eating into public trust in Merkel and even leading to a far-right party -- the anti-Islam, anti-immigration AfD -- gaining a meaningful presence in parliament for the first time since the Nazi regime.

Some authorities were overwhelmed and the chancellor was blamed for the "chaotic" situation, even within her conservative ranks.

Thomas de Maiziere, then interior minister, admitted recently that there had been a "loss of control" at times.

And then there were the damaging headlines. On New Year's Eve 2015, mass sexual assaults were committed against women in Cologne, mostly by men of North African origin.

A year later in December 2016, Anis Amri -- a rejected asylum seeker from Tunisia and known radical jihadist -- hijacked a truck and ploughed it into a crowded Christmas market in central Berlin. Twelve people died.

Events like these in turn fuelled right-wing anger, leading to demands from the AfD that "Merkel must go".

After the European Union made a controversial agreement with Turkey in 2016, the flow of migrants arriving in Germany slowed dramatically.

But Merkel was punished in 2017 federal elections when the AfD was voted into parliament as Germany's largest opposition party.

European and regional elections in 2018 confirmed the decline in Merkel's popularity.

At the end of 2018, she resigned as head of her party, the CDU, but said she intended to remain chancellor until the end of her fourth term in 2021.

Many doubted that she would make it that far -- until the pandemic came along.

- 'Not finished' -

Five years on from the refugee crisis, Germany "has become more diverse, more colourful, younger", according to the Pro Asyl migrants' association.

By the latest count, around half the migrants who arrived in Germany during the crisis are now employed -- a figure held up by the Institute for Employment Research (IAB) as a success story.

Merkel on Friday pointed to successes in integrating refugees into the job market and German society.

"Nevertheless, the subject will continue to be of concern to us and will remain so in the years to come," she said.

"The subject of migration... is not finished. It will be a constant theme for the 21st century."

See the original post:

Migrant crisis: Five years after refugee influx, Merkel 'would do the same' - RTL Today

New-age digital raths and e-electioneering new normal; Bihar elections test for parties – The Tribune India

Vibha Sharma

Tribune News Service

New Delhi, September 4

Call it the status quo in Bihar or winds of change as the BJP prepares to roll out its high pitch e-blitzkrieg powered by money and resources, the question is can the rivals match it to turn the situation in their favour.

Those associated with grass-roots in the poll-bound state believe it is possible as the ground reality, like in Jharkhand (Assembly elections), is far from what it appears from far.

Digital raths and e-electioneering are the new normal in the COVID times. In those terms, the upcoming Bihar elections will not just test parties but also the voters of the state where caste combinations, social situations and poverty continue to be the biggest issues.

This time, there is more.

According to political observers, thecombination of the coronavirus pandemic, resultant migrant crisis and job losses, and recent floods have the potential to lead to some unexpected results.

If you think Sushant Singh Rajput is an issue, think again. Ram Mandir is not an issue in the state where anything related to Mandal Commission (reservation) still has the potential to knock down a party as it happened with the BJP in 2015. The votes and issues of the backward classes, the EBCs and the Muslim community will decide the fate of the parties. The upper castes have their own grievances. The floods have played havoc and large tracks of farmlands have been submerged. Parties have to keep all that in mind, the experts say.

As far as the saffron party is concerned about digital and social media and high-tech campaigns, it is more experienced than others. Its e-campaign focusing on virtual rallies and digital raths with LED screen mounted atop vehicles for the live telecast of campaigns to take care of those whose who do not have smartphones or internet connection is ready. Party cadres will also be conducting nukkad or corner meetings with a limited audience and maintaining social distancing. Election guidelines will further define the contours and specifics of physical rallies and meetings, party leaders say.

The BJPs focus areas include Prime Minister Narendra Modis self-reliance pitch (Atmanirbhar Bihar) and monetary help, rations and the MNREGA jobs to migrants after they reached Bihar during the COVID-19 lockdown.

Read more here:

New-age digital raths and e-electioneering new normal; Bihar elections test for parties - The Tribune India

Protection beyond reach – State of play of refugee and migrant children’s rights in Europe – World – ReliefWeb

Over 200,000 lone child migrants left to uncertain fates in Europe

Five years since the tragic death of Alan Kurdi, Save the Children is warning that Europe has failed to address the needs of migrant and refugee children

Brussels, September 2nd - Some 210,000 unaccompanied children sought asylum in Europe over the past five years, fleeing conflict, persecution or violence, a new report by Save the Children said today. The total number of children arriving is likely to be much higher, with many being forced into an existence in the shadows of Europe, at risk of exploitation and abuse.

In the same period, more than 700 children, including babies, lost their lives trying to reach European shores[i], during perilous journeys by sea.

While some of the children have been offered safety and protection, many struggle to get a refugee status, live in constant fear of being deported or detained, and are unable to reunite with family members living elsewhere in Europe , the report Protection Beyond Reach by Save the Children reveals.

Children, travelling alone or with their family, have unique needs and must be offered safety and protection, yet the EU responded with increasingly restrictive and dangerous measures, Save the Children said.

It is five years to the day since Alan Kurdi lost his life just off the Turkish coast, becoming a tragic symbol of the refugee crisis. European leaders were among the first to say: Never again, but ever since, they have only made routes more difficult and dangerous for refugees and migrants, said Anita Bay Bundegaard, Director of Save the Children Europe.

The way Europe has treated the most vulnerable children in their hour of need is unacceptable. On any given day since August 2019, an average of 10,000 children were stranded on the Greek islands, 60% of them are under 12 years old. While some efforts were made to relocate children out of Greece, thousands have been abandoned due to the unwillingness of some European countries to take in and care for some of the most vulnerable children in the world. Children continue to die on the EUs doorstep while European leaders look the other way, Bay Bundegaard continued.

Many children are fleeing from countries facing ongoing or protracted crises. With the conflict in Syria in its tenth year, half of the countrys eight million children have known nothing but war. The conflict in Afghanistan where most unaccompanied children in Europe are from remains among the deadliest for children, who make up almost a third of all casualties in the country[ii].

Many European countries responded to the migrant crisis by shutting their borders, facilitating detention of children or making it nearly impossible for children to be reunited with their parents - in Greece alone, some 331 children were in detention in March 2020.

Ahmed, a 15-year old boy who fled Syria and is now in Belgrade, Serbia, said: When we try to cross the borders we get beaten by the police, badly. They are often very rude. I think they want us to feel afraid to try again. I havent seen my family for a long time now, I left to go to Europe because there was nothing for me in Syria, or Lebanon, or Turkey."

Children suffer nightmares and other symptoms of trauma and depression, including self-harm because of their experience in their country of origin and the arduous journey, their permits of stay being under constant review and their fears of being deported[iii].

While some improvements have been made,[iv] these are overshadowed by harsh border policies and measures to prevent vulnerable children from entering Europe altogether. Europe needs to draw lessons from the past. New migration policies should not come at the cost of childrens lives, continued Anita Bay Bundegaard.

Based on data compiled by organisations such as Eurostat, UNHCR and IOM Save the Children found that:

Ahead of the EUs announcement on new measures on asylum and migration, Save the Children is calling for the rights of children need to be at the heart of those decisions and for the EU and its leaders to ensure that steps are taken to keep vulnerable children safe. They must ensure that children can immediately access asylum and protection once they arrive to Europe, instead of being pushed back. More and better legal migration pathways, including swift access to family reunification, could prevent more children from dying on their way to Europe.

ENDS

See more here:

Protection beyond reach - State of play of refugee and migrant children's rights in Europe - World - ReliefWeb

Gary Lineker reveals hes inviting migrant to live at 4m house because his kids are grown up and got plenty – The Sun

GARY Lineker has revealed he will house a refugee in a few weeks as his kids are grown up and he has plenty of room.

The Match of the Day host, 59, said to be worth over 30million, is giving up one of the five bedrooms at his 4m Surrey mansion.

6

Last month Lineker was challenged by a Tory MP to offer his townhouse to refugees after accusing him of "virtue signalling" over the migrant crisis.

The ex-England striker told the Mirror: "My kids are all grown up so Ive got plenty of room so if I can help on a temporary basis then Im more than happy to do so. Why not?

"Most of the things we think of as quintessentially British are often brought in from different shores. Even St George is Turkish.

I just think we owe a lot to refugees and most people are descended from refugees at some point.

They have given so much to this country and still continue to do so in terms of the jobs they do which we have witnessed during the pandemic in the NHS, carers and key workers.

The former Spurs and Barcelona striker, who has four sons in their 20s, was interviewed by a charity who came to visit his home during the application process.

Refugees at Home has helped find temporary accommodation for more than 2,250 vulnerable people.

It comes after a record 409 migrants crossed the Channel yesterday.

Lineker, who earned 80 caps for England during a glittering career, admits he has no idea who will be staying with him and what country they are from.

6

6

6

The BBC host began campaigning for refugees after the death of Alan Kurdi - a Syrian child who drowned near Greece in 2015.

And news of a Sudanese man dying while attempting to cross the Channel, prompted Lineker to take action.

He said: "It was seeing the images of what was happening when they were going in the boats and landing in Greece, seeing families dying, it just struck me as so intolerably sad.

FINE LINEGary Lineker dismisses BBC boss's warning to staff to keep views off social media

STAY AT MY PLAICEGary Lineker thanks refugees for 'giving Britain fish & chips'

NEW HOMEIs Gary Lineker inviting a migrant to live in his house?

Exclusive

'I CAN'T SEE'Gary Lineker's eyesight is so bad he struggles to read Match of the Day notes

VIDEO NASTYMan City hero Sterling watched Spurs defeat highlights before toppling Madrid

Imagine if it was London that was being bombed and we had to flee somewhere and nobody would accept you and nobody would want us and everyone would hate you.

The former England striker will also appear in a new film highlighting how fish and chips came from Jews fleeing persecution in Spain and Portugal, as part of an initiative highlighting refugees' contributions.

He will appear alongside comedian Jo Brand and TV actor Yasmin Kadi star in a new film exploring the origins of the popular dish on Friday.

He tweeted: "Providing a new start to those who have fled their homes represents the best of Britain's values. As we know refugees have always helped to keep our communities safe and make our society stronger. They even brought us fish & chips."

Lineker has praised young footballers such as Marcus Rashford for speaking out about social issues calling their maturity "extraordinary."

The father-of-four is supporting the International Rescue Committee campaign which raises awareness of the migrant crisis.

6

View post:

Gary Lineker reveals hes inviting migrant to live at 4m house because his kids are grown up and got plenty - The Sun