What will dexamethasone do to President Trump? – Massive Science

The president has had a life-threatening, infectious disease for over a week, and he and his doctors havent been very transparent about the timeline and course of his affliction. In lieu of detailed disclosures, reporters have to piece together his condition based on the treatments hes been receiving.

Trump was started off on an experimental therapeutic an antibody cocktail and then advanced to another remdesivir. The other biomolecules coursing through Donald Trump's system (and this week's headlines) are corticosteroids, called dexamethasone.

You may have heard of cytokine storms, where the body's immune response to severe COVID-19 bombards healthy cells, making the illness worse. Trump has been given dexamethasone, an immuno-supressant that doctors prescribe to temper that effect. Unlike the other experimental treatments, dexamethasone is common and somewhat easy to access. However, it is rarely administered to a patient with a case as (self-)reportedly mild as Donald Trumps. In an interview with New York Magazine's Intelligencer, the co-author of a recent study testing dexamethasone elaborates:

That lack of evidence is concerning as Trump heads into a critical point in the course of his illness. COVID-19 is known for being a bit of a roller coaster, with intermittent fevers, mysterious symptoms, and rapid declines. Abraar Karan, a physician with experience treating patients with COVID-19, told Monique Brouillette at Scientific American that some people have turned corners and left the hospital, only to come back feeling much sicker, with even worse oxygen levels and possibly other harm to the bodys organs.

It is theoretically possible that the early steroid treatment may ward off a dangerous auto-inflammatory reaction. But beyond the inherent risks of immuno-supression, corticosteroids may also cause behavioral side effects in the President. Trump's cognitive and behavioral state has been a point of concern for years. Potent steroids such as dexamethasone are known to increase appetite, decrease restful sleep, and bring about heightened "maniacal" energy states.

As the nation enters the weekend, Speaker of the House Nancy Pelosi is rolling out a 25th amendment commission, Trump is boasting a miraculous recovery with a Fox News doctor, and the rest of us continue to wait and learn how biology will run its course. For better or worse, the side effects our president experiences may prove to have historical consequences. To my knowledge, roid rage has never been a factor in nuclear geopolitics.

Read more here:
What will dexamethasone do to President Trump? - Massive Science

What would comprehensive sex ed look like in Spokane-area public schools? Here’s what might change if R-90 passes this November – The Spokesman-Review

On the November ballot, Washington voters will decide if public schools should be required to teach comprehensive sexual health multiple times during a students K-12 education.

Supporters say the bill will give all Washington students equal access to sex ed, protect students from sexual abuse and harassment, and help them make healthier decisions.

Opponents say its so much more than that, arguing the bill doesnt provide enough local and parental control and teaches young students graphic information about sex. However, the lessons taught in kindergarten through third grade only require social-emotional learning, according to the bill. Nothing about sex is taught.

So what will really change if Referendum 90 passes this November? The Spokesman-Review looked at current sex ed materials throughout the Spokane area, as well as bill requirements and OSPI guidelines.

Heres what you need to know.

Background

The controversial sexual health education bill passed both chambers of the state Legislature in March with only Democratic votes. Gov. Jay Inslee signed it into law later that month.

Referendum 90 was put on the ballot after a grassroots effort gathered a record number of signatures to put the referendum on the ballot. More than 266,000 signatures more than twice the minimum required were filed with the Secretary of States office. The referendum will ask voters if they approve or reject the bill that requires age-appropriate sexual health education to be taught to students multiple times from kindergarten to 12th grade.

Voters will be asked to vote yes if they support the sex ed bill as passed, or no if they want to see it repealed.

What will it actually change?

If Referendum 90 passes and the law is affirmed, the biggest change will be that every school in Washington will now have to provide sexual health education.

With the new law, school districts still have the opportunity to decide their own curriculum, and parents still have the opportunity to opt their children out, according to the bill.

Current law mandates HIV/AIDS prevention education but allows school districts to decide if they want to provide sexual health education.

Most school districts already teach some form of sex ed, even if it is not considered comprehensive, as defined in the new law.

Currently, state law doesnt require public schools to teach sex ed. But if they do teach it the curriculum must include:

If Referendum 90 passes, the only addition to that list is: Affirmative consent and recognizing and responding safely and effectively when violence, or a risk of violence, is or may be present with strategies that include bystander training.

Affirmative consent means a conscious and voluntary agreement to engage in sexual activity as a requirement before sexual activity, as defined in the bill.

In addition to consent, the new law will require sex ed to be taught in multiple grade bands: once in kindergarten through third grade, once in grades 4-5, twice in grades 6-8 and twice in grades 9-12 .

Students in kindergarten through Grade 3 must have social-emotional learning that is consistent with standards set by the Office of the Superintendent of Public Instruction, according to the bill. In OSPI guidelines, social-emotional learning teaches how to identify and express feelings, how to achieve goals and how to act responsibly when interacting with others, among other guidelines.

If school districts decide their own curriculum, they must ensure it meets all requirements as laid out in the law, and they must allow parental and community input.

We dont have a final say, said Laurie Dils, OSPI sexual health education program supervisor.

For some districts nothing will change based on the outcome of the November election, as their curriculum meets the proposed requirements. This means the district is already teaching social-emotional learning and consent in K-3. Other schools will have to rethink their curriculum phasing it in over the next three years.

Spokane Public Schools

Spokane Public Schools will be unaffected by the new law, if it passes, as their curriculum currently meets the new standard, according to Heather Bybee, the districts director of secondary curriculum.

Spokane students in kindergarten, first and second grades receive instruction in what the district calls personal safety. These early lessons focus on informing trusted adults of suspicious activity, both online and in the real world. One instructional animated video features a brightly colored robot named Clicky rapping a message to kids, encouraging them to say no to strangers who offer them gifts or ask to take them somewhere.

Students begin receiving instruction about gender identities and sexual orientation in fourth grade under a new set of materials adopted by the Spokane School Board of Directors in June. Instruction includes another animated video featuring various anthropomorphic fruits and vegetables comprising whats called a love salad, with definitions not only for gay and lesbian orientations but also pansexual and asexual people.

There are currently no requirements for teaching about gender identities and sexual orientation at any grade level, Dils said, and that will remain the case if Referendum 90 passes.

Students in fourth and fifth grades are also asked to examine stereotypes about genders, and how the media both social media and traditional entertainment like movies, TV and advertising enforce those beliefs. In fifth grade, students are introduced to the topic of sexually transmitted diseases, including HIV, and the ways in which the virus is and isnt transmitted.

Sixth-graders learn about the differences between romantic and nonromantic relationships through scenarios.

Seventh-graders receive instruction on making positive health choices, including whether to have sex. The stages of pregnancy are first discussed. Instructors also review what health services are available to minors, including abortion services, with and without parental consent.

During a 15-day curriculum for eighth-graders, students are instructed about consent for sexual activity. Classroom discussion includes statistics on teenage access to pornography, and how the images and videos are distorted presentations of reality that perpetuate troubling gender stereotypes.

Abstinence is taught as the only method to eliminate the threat of sexual transmitted diseases, but eighth graders also receive instruction on what methods of contraception are available. During high school health courses (grades nine and up), students can choose whether to participate in a hands-on demonstration of properly using a condom, or they can opt out and order the written-out steps instead.

High school students watch a video called Big Status Update that dramatizes a teen pregnancy and its many demands through messages and status updates on the screen of a smartphone.

Central Valley

The Central Valley School District will likely only need to make minor changes to its curriculum if Referendum 90 passes, based on the 2018 OSPI survey and copies of the lessons obtained by The Spokesman-Review.

The biggest changes in Central Valley will likely be the frequency at which sex education is taught and the addition of consent and bystander training.

In kindergarten through third grade, Central Valley teaches a social-emotional learning program called Second Steps, according to communications director Marla Nunberg.

Similar to OSPIs guidelines, the lessons often focus on dealing with emotions and taking care of mental health, Nunberg said. This is something that has been important during the COVID-19 pandemic, she added.

Human-growth and development lessons start in fourth grade, when students learn about puberty. Boys and girls are separated for their lessons and are shown videos on the physical and emotional changes that occur during puberty. Students are also taught how to make healthy choices, such as exercising and eating well.

In middle school, students are taught specific ways sexually transmitted diseases and HIV are transmitted, as well as the stages of pregnancy and the ways to reduce the risk of pregnancy and STDs. Middle schoolers are also taught responsible behaviors and practices, and how they influence relationships.

In high school, students learn how to further protect themselves from STDs and HIV, and the importance of making educated decisions when having sex.

Mead

The Mead School District will likely only need to make minor changes to its curriculum, including the frequency at which sex ed is taught and the addition of consent and bystander training.

The district may also need to start teaching social-emotional learning in kindergarten through third grade, but Dils said most teachers already teach some form of that, even if its not a specific curriculum.

We would need to review the exact requirements and definitions in the new law, if passed, to ensure we are in alignment, wrote Todd Zeidler, district public information officer, in an email.

Mead currently provides sexual health education once per year in grades 5, 6, 7, 8 and 9, Zeidler said.

In fifth grade, students are taught the basics of puberty as well as HIV/AIDS transmission. Lessons also focus on decision-making and self-esteem. Teachers encourage students to wait until they are older to have sexual intercourse.

In sixth grade, students begin learning about human reproduction. Seventh grade focuses on making responsible decisions and preventing STDs.

In eighth grade, students learn about the importance of healthy relationships and receive a list of local resources and what they offer, such as contraceptives or testing.

Ninth grade lessons focus on human sexuality and the reproductive system, the effects of healthy relationships, prevention resources and how to protect yourself from criminal sexual behavior.

Liberty

The Liberty School District may have to make a few changes to its curriculum, according to OSPI available data as well as documents obtained by The Spokesman-Review.

The school district currently teaches the KNOW curriculum, the states HIV/STD prevention curriculum, at least once in all grade bands. It also teaches a curriculum called Always Growing and Changing in later grade levels.

The use of the KNOW curriculum meets the requirements of the AIDS Omnibus Act, but it does not meet all of the requirements for the new law, Dils said.

Because it addresses only HIV/AIDS prevention, it is not a comprehensive sexual health curriculum, Dils wrote in an email.

Superintendent Brett Baum said the district is in the process of reviewing its materials and will be updating them if the new law is enacted.

Deer Park

The Deer Park School Districts curriculum does not meet the comprehensive sex ed requirements, Superintendent Travis Hanson said. It currently only teaches the states required HIV/AIDS prevention with students in Grades 5 through 12 using the KNOW curriculum.

The district was in the process of reviewing its current curriculum and adopting a more comprehensive one last year, Hanson said. However, once the Legislature began looking into a statewide mandate, Deer Parks process paused.

If Referendum 90 does not pass, Hanson said the district will revisit the adoption process.

Opponents

Multiple organizations, coalitions and committees formed to oppose the comprehensive sex ed bill, arguing that it allows for too much state control and includes graphic curriculum.

Mindie Wirth, chair of Reject Referendum 90 Campaign, led the movement to get the measure on the ballot.

This issue has drawn bipartisan support as many people across Washington State grow increasing frustrated with the ongoing overreach into our daily lives by Olympia, Wirth, of Bothell, wrote in an email. Many individuals have stated that they have never been active on a political issue until getting involved in Referendum 90.

Anniece Barker at A Voice for Washington Children said she was concerned about the bill when she realized most of her friends and family didnt even know it existed.

When Barker, who is from Spokane, started to tell people about it, she said they were stunned.

Her biggest concern is a lack of parental and district control in decisions. Parents can still opt their children out and districts still have the opportunity to choose their own curriculum, but for Barker, it is not enough.

For the state to come in and say they know better than parents about what is age appropriate, that in itself is inappropriate, Barker said.

Barker said she is not against sex ed.

Curriculum really isnt the point about it, she said. Its about giving parents the right to decide whats right for their child.

Kim Wendt, co-founder of Informed Parents of Washington, said the bill does not allow enough choices for school districts. She said the state allows districts to choose a curriculum, but that curriculum must be comprehensive, something she called a radical philosophy.

There is no real choice here, Wendt said.

For Wendt and Jennifer Heine-Withee, president of the Southwest Washington Parents Rights in Education, the biggest concern is the curriculum that is being taught. Although the bill states the K-3 requirement is only for social-emotional learning, Heine-Withee said she is worried including Grades K-3 in this bill will allow school districts to teach sexual health education to younger grades.

You put a door there, and theres going to be teachers going through it, she said.

Wirth said school districts should be focusing on other programs instead of sexual health education, such as improving literacy and graduation rates.

At a time when state and local budgets are facing massive deficits which threatened funding for basic programs, schools cannot afford to add an expensive new requirement, or design their own curriculum that meets those same state standards, Wirth wrote in an email.

Supporters of the bill say it allows for more parental and local control than before and gives students across the state equal access to sex ed.

A coalition called Approve 90 formed this summer in support of the referendum. It includes parents, teachers and larger organizations such as Planned Parenthood, the Washington State Public Health Association and the Washington Chapter of the American Academy of Pediatrics.

The coalition and its supporters argue that comprehensive sexual health education will make kids safer by making them less likely to take part in risky sexual behavior and by improving health equity across the state.

Erin Williams Heuter, of Lutheran Community Services Northwest in Spokane, said she believes comprehensive sex ed protects children from sexual abuse and harassment.

Survivors of sexual assault often experience shame and guilt, which leads to them struggling to talk about it, Williams Heuter said. Being able to speak about sex in general more comfortably will likely prevent sexual abuse.

We want to make sure all kids have a safe person to talk to, she said. It really makes everybody safer.

Mandy Manning, 2018 National Teacher of the Year and Spokane teacher, said in her experience, kids actually want sex ed taught in their schools.

She said teaching consent, which is the biggest change with the new bill, will make more students safer.

How great for teenagers to know that they are the ones who get to be in control, she said.

Courtney Normand of Planned Parenthood said there is still plenty of flexibility with the new law. Parents can opt out their children from the courses, and districts can decide their own curriculum.

Including K-3 in the bill has been controversial, but Normand said its important for kids to have social-emotional learning at an early age as it can lead to less abuse or harassment.

Dr. Matt Thompson, a pediatrician with the Kids Clinic in Spokane, said the bill is necessary to provide children with accurate information about their health and their safety.

This allows students to have accurate information and make better decisions, and to be more aware of consequences of their actions, he said.

Spokesman-Review reporter Kip Hill contributed to this report.

Laurel Demkovich's reporting for The Spokesman-Review is funded in part by Report for America and by members of the Spokane community. This story can be republished by other organizations for free under a Creative Commons license. For more information on this, please contact our newspapers managing editor.

Original post:
What would comprehensive sex ed look like in Spokane-area public schools? Here's what might change if R-90 passes this November - The Spokesman-Review

Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke – Science Advances

Failure of neurons to efficiently repair DNA double-strand breaks (DSBs) contributes to cerebral damage after stroke. However, the molecular machinery that regulates DNA repair in this neurological disorder is unknown. Here, we found that DSBs in oxygen/glucose-deprived (OGD) neurons spatiotemporally correlated with the up-regulation of WRAP53 (WD40-encoding p53-antisense RNA), which translocated to the nucleus to activate the DSB repair response. Mechanistically, OGD triggered a burst in reactive oxygen species that induced both DSBs and translocation of WRAP53 to the nucleus to promote DNA repair, a pathway that was confirmed in an in vivo mouse model of stroke. Noticeably, nuclear translocation of WRAP53 occurred faster in OGD neurons expressing the Wrap53 human nonsynonymous single-nucleotide polymorphism (SNP) rs2287499 (c.202C>G). Patients carrying this SNP showed less infarct volume and better functional outcome after stroke. These results indicate that WRAP53 fosters DNA repair and neuronal survival to promote functional recovery after stroke.

Read the original here:
Nuclear WRAP53 promotes neuronal survival and functional recovery after stroke - Science Advances

The coronavirus can survive on skin for this many hours, study suggests – Fox News

New research out of Japan suggests the novel coronavirus can live on human skin for up to ninehours.

In a study published in the journal Clinical Infectious Diseaseson Oct. 3, researchersfrom the Kyoto Prefectural University of Medicinefound that SARS-CoV-2outlived the influenza A virus (IAV) on human skin, which remained viable for about twohours.

New research out of Japan suggests the novel coronavirus can live on human skin for nine hours. (iStock)

The researchers generated a model that allows the safe reproduction of clinical studies on the application of pathogens to human skin and elucidated the stability of SARS-CoV-2 on the human skin, they wrote. The models were created from samples of human skin taken from autopsies, per Live Science.

CORONAVIRUS OUTBREAK AT NORTH CAROLINA HAIR SALON TIED TO AT LEAST 1 DEATH

Using the model, the researchers found the survival of SARS-Cov-2 was significantly longer compared to IAV, with 9.04 hours and 1.82 hours, respectively.

When both viruses were subsequently mixed with mucus to imitate a cough or sneeze, the novel coronavirus lasted about 11 hours, the researchers found.

OKLAHOMA CORONAVIRUS HOSPITALIZATIONS HIT RECORD HIGH FOR STATE

Thankfully, however, both SARS-CoV-2 and the influenza A virus were completely inactivated within 15 [seconds] by ethanol treatment, or hand sanitizer containing 80% ethanol, they said.

The 9-[hour] survival of SARS-CoV-2 on human skin may increase the risk of contact transmission in comparison with IAV, thus accelerating the pandemic. Proper hand hygiene is important to prevent the spread of SARS-CoV-2 infection, they concluded.

EMERGENCY COVID-19 VACCINE APPROVAL TO REQUIRE 2 MONTHS OF FOLLOW-UP DATA, FDA SAYS

The study had at least one limitation, however. The researchers in their review did not consider the viral load needed to cause a COVID-19 infection from contact with contaminated skin, Live Science noted.

The research comes after a separate study conducted early on in the pandemic, in March, found that the novel virus can live on surfaces such as plastic and stainless steel for up to three days.

CLICK HERE FOR COMPLETE CORONAVIRUS COVERAGE

Thatresearch, published in the medRxiv depository, noted that the virus can remain on copper surfaces for four hours and carboard for up to 24 hours. The research also found it could stay on stainless steel and plastic for anywhere between two and three days.

Fox News Chris Ciaccia contributed to this report.

Read more here:
The coronavirus can survive on skin for this many hours, study suggests - Fox News

Edelweiss launches India’s first passive index fund for healthcare sector with MSCI – ETHealthworld.com

Mumbai: Edelweiss Asset Management on Monday announced a partnership with MSCI to launch the country's first passive thematic index fund which will bet on 45 healthcare companies from India and abroad. The company feels that healthcare as a category has under-performed over the last two years during which it has seen issues like difficulties in getting US FDA licenses, and will do better in the future due to which the offering has been launched through a tie-up with MSCI.

Radhika Gupta, the chief executive of Edelweiss AMC, told reporters that the fund will invest 70 per cent of its corpus in 25 top local companies and the remaining 30 per cent in global ones listed in the US.

It is a passive fund and the investment decisions will not be done by humans at all, she said, adding that this is first in a series of collaborations between Edelweiss and MSCI.

Apart from growing demand, export opportunities and a conducive policy environment are also a growth driver for the sector, she added.

The new fund offering for the 'Edelweiss MSCI India Domestic & World Healthcare 45 Index Fund' will open on Tuesday and close on October 20.

Follow this link:
Edelweiss launches India's first passive index fund for healthcare sector with MSCI - ETHealthworld.com

What You Should Know About PCOS and Fertility – LIVESTRONG.COM

Many tactics can help people with PCOS get pregnant, from losing weight if necessary to surgery to certain medications.

Image Credit: Jose Luis Pelaez Inc/DigitalVision/GettyImages

Polycystic ovary syndrome or PCOS is one of the most common causes of infertility among people with ovaries, according to the Office of Women's Health (OWH).

In fact, PCOS is the most common hormone-related issue in women having difficulty conceiving, says David Diaz, MD, reproductive endocrinologist and fertility expert at MemorialCare Orange Coast Medical Center in Fountain Valley, California.

The condition affects between 6 and 12 percent of those with childbearing reproductive organs in the United States, according to the Centers for Disease Control and Prevention (CDC).

But it is possible to get pregnant with PCOS. Here's what you need to know about PCOS and fertility and what treatments are available.

Polycystic ovary syndrome is derived from the Greek words poly, which means "many" and kystis, meaning, "bladder, pouch," Dr. Diaz explains. Hence, the name implies that an organ in this case, the ovaries has "many cysts."

Due to an imbalance of hormones, the eggs in the ovaries of people with PCOS either don't develop normally or aren't released as they should be. As a result, small cysts develop on the ovaries. But having cysts on the ovaries doesn't necessarily mean that you have PCOS, Dr. Diaz says. PCOS is only diagnosed with the presence of ovary cysts along with other symptoms.

"In treating PCOS, it is best not to use a cookie-cutter approach since no two patients are alike."

For people with PCOS, it's common for doctors to find more than 15 to 20 sacs that are eggs in development on each ovary (compared to the normal six to seven typically found), Dr. Diaz says.

"This means there is no lack of eggs, but that they are simply stunted in their growth process," Dr. Diaz notes.

How PCOS Affects Fertility

The exact cause of PCOS is not known, but it's thought to be a combination of different factors, including genetics, that lead to insulin resistance the body's inability to use the hormone insulin properly and a change in hormone regulation, which will ultimately interfere with normal ovulation (the process of an egg being released from the ovaries).

Many people don't get diagnosed with PCOS until they are trying to get pregnant and are unable to conceive.

PCOS is different for everyone, Dr. Diaz says. For instance, some people will be more sensitive to hormone changes, which could make their symptoms more severe.

Although PCOS varies from one person to another, common symptoms, per the OWH, include:

What's difficult about PCOS symptoms is that they are often linked together as well, so the symptoms can become a vicious loop.

For example, Dr. Diaz explains that the menstrual cycle is regulated by the ovaries, which are in turn regulated by hormones. Any abnormality due to high insulin levels and insulin resistance disturbs the normal release of the hormones needed for ovulation, which then throws off the menstrual cycle.

High insulin levels also activate the formation of androgen hormones, which in turn, also stop normal ovulation from occurring. And finally, the high rates of obesity in PCOS patients results in excessive levels of androgens and estrogen, which will stop the hormones needed to regulate ovulation.

How Do You Know if You Have PCOS?

Diagnosing PCOS can be tricky, since it's different for everyone. There is no one single test that can show you have it. Instead, clinicians look for clues that can point to the root causes of your symptoms, Dr. Diaz says.

Doctors typically look for signs of PCOS using a combination of blood tests, physical examination and a pelvic ultrasound.

PCOS Treatment Options if You're Trying to Conceive

While there is no one cure for PCOS, treatment is possible, Dr. Diaz says.

"PCOS is a multi-factorial condition, meaning there are many different organ systems involved," he explains. "Familiarity with hormonal function and a clear understanding of the endocrine system are paramount in designing a treatment plan. In treating PCOS, it is best not to use a cookie-cutter approach since no two patients are alike."

Individuals with PCOS should work with their doctors to come up with a treatment plan that addresses their own specific needs. Dr. Diaz says. However, the following treatments are often used for people with PCOS looking to get pregnant.

Weight loss has positive effects on PCOS symptoms, from regulating periods to improving hair growth and acne. It can also help your chances of getting pregnant, according to the American College of Obstetricians and Gynecologists (ACOG).

In fact, weight loss is often the first treatment recommended for people with PCOS who have weight to lose. About 40 to 60 percent of people with PCOS are considered to have overweight or obesity, per a December 2019 article in Clinical Medicine Insights Reproductive Health.

Compared to taking birth-control pills, lifestyle modifications aimed at weight-loss improved ovulation rates for people with PCOS, per a November 2015 study in the Journal of Clinical Endocrinology & Metabolism.

However, because of the complexities of losing weight with PCOS (the hormone imbalances typical of condition may make losing weight difficult, for instance), it's also recommended that all factors be considered for infertility. If the person who wishes to get pregnant is on the older side, for example, it may be best to focus on reproductive assistance techniques first instead of weight loss.

Weight loss can be achieved through a variety of lifestyle modifications with PCOS, but incorporating exercise into your daily routine is associated with improved fertility, per the Clinical Medicine Insights Reproductive Health article.

Aim to get 150 minutes every week of moderate-intensity physical activity or 75 minutes per week of vigorous-intensity activity, combined with two non-consecutive days of muscle strengthening activities, per guidelines published in July 2018 in Fertility and Sterility.

If you want to lose weight, try to get 250 minutes per week of moderate-intensity exercise or 150 minutes of vigorous exercise, along with strength training, per the guidelines.

Because weight loss can be difficult for people with PCOS, some individuals may be a candidate for weight-loss surgery. Bariatric surgery can help people with PCOS both manage their symptoms and improve their fertility and chances of getting pregnant, per an October 2016 overview in the European Journal of Obstetrics and Gynecology and Reproductive Biology.

However, there are risks involved with surgery, including a possible chance of babies who are small for their gestational age, so you should consider the procedure carefully with your doctor.

Medications for PCOS aim to regulate your hormones to increase your chances of ovulating on your own or help your body maintain your blood sugar levels. They can help both manage symptoms and increase your chances of conceiving.

For instance, insulin-sensitizing drugs like Metformin can help your body use insulin more effectively and help restore ovulation, per the UK's National Health Service.

Doctors may use clomiphene to induce ovulation, letrozole, which can help balance estrogen levels (which can also help your body naturally ovulate) and if necessary, thyroxine may be prescribed for hormone regulation, Dr. Diaz says.

Some people may also have hyperplasia, which is excessive tissue in the uterus that can often be treated with progestin. This hormone can be given in a variety of ways, including oral medications and creams, according to ACOG.

Hyperplasia can occur with PCOS because as your body prepares to ovulate, the lining of the uterus thickens in preparation for a possible pregnancy. If pregnancy isn't achieved, the lining is shed. If ovulation does not occur or if the hormones necessary to complete the process are not at adequate levels, the lining is not shed. Overtime, this process may cause the uterine lining to build up.

There is a potential link between stress and PCOS, so managing your stress levels may be helpful in minimizing symptoms and improving fertility, per a January 2018 study in the Journal of Human Reproductive Sciences.

Reproductive Assistance Technologies

Dr. Diaz points out that if there are other barriers to getting pregnant, such as a partner's low sperm count, blocked fallopian tubes or recurrent miscarriages, in-vitro fertilization (IVF) may also be an option.

If you are having trouble getting pregnant, visit your doctor or a fertility specialist who will screen you for possible reasons, including PCOS. Getting a diagnosis enables you and your doctor to work on a treatment plan that can help you conceive.

See the original post:
What You Should Know About PCOS and Fertility - LIVESTRONG.COM

Viable Use Nanotechnology: The Future Has Arrived – Techopedia

Intels stunning fumble in the execution of its plan for 7 nm nanochips, rocked stock markets. The incident brought into dramatic relief the crucial role of nanotechnology for the future of the semiconductor industry.

In a single day of trading, the company lost a whopping forty billion dollars indicating how much keeping pace with nanotechnology will affect its prospects. By contrast, AMD and Taiwan Semiconductor Manufacturing rose over fifty percent after their most recent announcement of earnings.

The end of Moores Law has accelerated innovation in chip design aided by nanotechnology. (Read also: More Than Moore: 50 Years of Moore's Law.) As chips size becomes infinitesimally small, memory, processing, storage, and sensors, are assembled into single system-on-a-chip,

Join nearly 200,000 subscribers who receive actionable tech insights from Techopedia.

Carbon nanotubes, the material used for such systems, have higher speeds, conduct electricity better, and generate less heat.

Sri Savamedam senior vice-president, CMOS technologies, at Belgium-based imec, a global R&D and product development company in nano and digital technologies industries, told us:

New materials innovations are needed to lower back-end resistance. Additionally, novel low-temperature semiconductors like IGZO ( (Indium Gallium Zinc Oxide) will find use in 3D DRAMs. 2D materials like WS2 will find use in new transistor channels. Finally, novel magnetic memories will gain currency,

The commercialization of nanotechnology is in the early days and expected to expand considerably in the next few years. We are working on several variations of IGZO class of materials (different phases, composition,) and expect to see improvements within the next year, Sri Savamedam concluded.

Over the medium term, crystalline 2D materials bring electrical, optical, and magnetic properties that improve performance. 2D materials (like WS2, MoS2) as channels are important to extend the CMOS roadmap beyond Si, SiGe, and Ge channel, Sri Savamedam informed us.

Much work is needed to grow these materials at a high quality using 300mm tools. It will likely take 2-3 years before we have breakthroughs in 300mm tools for these materials.

The Internet of Things and Edge computing have increased the demand for miniaturized connected devices. For example, in the Covid-19 context, microfluidics MEMS (Micro-Electro-Mechanical Systems) devices are capable of point-of-care diagnosis to detect the virus without delay sans a visit to a lab. These devices are particularly useful for repeated testing that the chronically ill need. In the Covid-19 context, they are also useful for rapid testing. (Read also: 5 Top Health Tech Trends.)

Existing methods of testing are overly expensive, slow, and unable to scale for pandemic situations. The golden standard of diagnosis is a molecular analysis (detecting viral RNA) by either PCR or next-generation sequencing. These techniques are sensitive (able to detect low quantities of the virus), and specific (the test results will not be affected by confounding factors such as the presence of other viruses). Current methods of molecular analysis need expensive infrastructure (lab, personnel, and equipment) to perform the tests, Peter Peumans, CTO Health Care Solutions, imec, told us in response to email questions.

The success of a molecular test depends critically on the pre-analytical steps (such as sampling and transport). Nanotechnology has the potential to address both challenges by bringing molecular tests to the point-of-need by making them more compact, easier to use, faster, and cheaper.

One such innovation is the company miDiagnostics, which was spun out of imec in 2015. miDiagnostics is using imecs silicon chip know-how to test at the point-of-need, Peumans informed us.

Cepheid is another such device in the Covid world, which binds specific nanoparticles like graphene to test for pathogens at the DNA level. Due to pinpointed targeting with nanoparticles, tests are far more specific and sensitive. By contrast, currently, most lab results are rife with false positives and false negatives besides taking about a week to complete.

Brain-machine interface is another application that is getting a boost from nanotechnology. Due to the nanosensors tiny size, the number of them used for picking brain signals increases by double-digit multiples, Gene Locklear, Senior Artificial Intelligence Research Scientist at Entrust Solutions, told us. He went on:

The processing of this many signals with AI is a forbidding challenge. Techniques from emergent learning are used to aggregate data before it can be analyzed. The methods are akin to flocks of birds that fly and return in concert. They have implicit rules by which the subordinate birds take cues from the lead bird without explicit guidance.

Reinforcement learning is a key tool which can model for the collective behavior and continuously learn from the data to achieve a predefined objective. When out of the lab, human users confirm the validity of the results, he added.

We spoke to Dr. Matthew Putman, Co-founder & CEO of Nanotronics, who worked on nanodevices in a university laboratory, before launching his venture ten years ago, to commercialize and scale them on an industrial scale. Dr. Mathew Putman told us:

Rapid advances in machine learning, deep learning, and reinforcement learning, automation, and imaging enable us to spot and correct errors to achieve quality standards for scalable and feasible nanotechnology.

For example, the traditional semiconductor lithography technologies are subtractive, i.e., they cut pieces from a larger slab of material. By contrast, nanotechnology is additive,i.e., it builds from bottom-up by joining nanomaterials to make a larger piece. AI and imaging technologies help to join nanomaterials precisely to achieve quality standards, Dr. Putnam explained. (Read also: Nanotechnology: The Biggest Little Innovation in Technology.)

In the past, the means for checking quality were limited to an atomic microscope or electron microscopy. You could see only an incredibly tiny part, a single nanoparticle, of a nano product or nano equipment. It was analogous to finding a needle in a haystack but not the larger formation or the product as a whole, Dr. Putnam recalled.

AI algorithms like reinforcement learning define the objective function or the properties for a product like graphene. One piece of the puzzle is the observed needle or the first nanoparticle. Accrued machine knowledge helps determine the remaining nanoparticles to produce graphene and align them precisely to achieve the desired quality. We reserve hardware for manual correction of only pinpointed errors, Dr. Putnam elucidated.

The precision that AI brings to the process is critical not only for manufacturing but also for the solutions possible with nanotechnology. The specificity and sensitivity of DNA level diagnosis of a disease like Coronavirus are contingent on its accurate sequencing, and the pathogen is identified right. Graphene, a nano product, binds with the DNA at the fault lines between nanoparticles for diagnosis. We feed the objective functionthe DNA sequenceof a pathogen that the algorithm verifies, Dr. Putnam concluded.

Machine intelligence does not preclude human creativityimaging technologies only augment it. Individuals and teams visualize nanoparticles networks, otherwise beyond their intuitive capabilities.

Teams collaborate based on the situational awareness gained from the visuals to solve problems machines cannot. Imaging provides a macro-image (which is itself micro in nanotechnology) but not molecular. Due to the limitations of physics, you cannot capture images of particles any smaller than that. Now there are computational tricks to construct product formation at a molecular level. You can now classify topologies previously undiscovered when viewed with a microscope or the human eye, Dr. Putnam informed us.

Nanotronics uses virtual reality and augmented reality to help their staff select the right algorithmic models and recalibrate them when the expected results fall short. Dr. Putnam observed:

We use 3D technologies to overcome human intuitions limitations and immerse in data otherwise hard to grasp and manipulate. Virtual reality transports them to an alternate world where they see the same imaging and alter it to visualize alternative scenarios. Augmented Reality helps direct the staff to move through this second life type world to make deft moves. Concurrently, we train the AI system as we put together the data and visualize it.

While the early viable uses of nanotechnology, in the semiconductor industry, are now proven, and lately, point-of-care diagnostics have shown promise, further progress hinges on much greater precision in the operating technologies. The room for error in the more advanced applications like DNA Origami or molecular scaffolding protein and catalytic engines for drug discovery is non-existent, so their viability is in the far horizon, Dr. Putnam surmised based on Nanotronics experience across several industries.

The near-term growth of uses has some prominent industries. There have been successes, such as sensors for smartphones. Nano is working for neuromorphic chips including sometimes for photonics, and genomic sequencing, RUV, IG Stack and new types of MEMS devices and sensors are candidates for near-term growth, Dr. Putnam concluded.

The complexity and the invisibility of nanotechnologys structure inhibited its growth. By removing these barriers with artificial intelligence and imaging, a new era of precision manufacturing and usage is poised for exponential growth driven by industries created with its help.

Follow this link:
Viable Use Nanotechnology: The Future Has Arrived - Techopedia

The Tiny Technology Helping Cannabinoid Balance By CBD Products Inc. Make A Big Splash – PR Web

LA JOLLA, Calif. (PRWEB) October 09, 2020

Nanotechnology has long been understood to support many facets of medical science. Researchers and manufacturers are taking this proven technology and are now applying it to one of the fastest growing consumer markets in the world - CBD. And no one has been more active in bringing this tiny technology to CBD consumers than CBD Products Inc, with their new nano inspired brand Cannabinoid Balance.

Having seen that nanotechnology could have a profound effect on absorption rates in the body, the team at CBD Products Inc. turned to NanoZorb to help deliver the cannabinoids and terpenes in their Cannabinoid Balance products into the bloodstream quicker.

As with so many things in science, Nano Technology works by increasing the contact area and in turn increases the rate of absorption. By using NanoZorbTechnology in their Cannabinoid Balance products, Anthony Tribunella realized that he could increase the rate of CBD uptake and make the process of absorption more efficient by bypassing the digestive tract and reducing the CBD degradation that occurs during digestion.

Nano Technology describes the creation of minute particles, so small in fact that millions of them could fit on to just one pinhead. These tiny particles are small enough to be absorbed directly into the bloodstream and delivered to every cell. This means that unlike traditional delivery methods, the constituents being delivered in Cannabinoid Balance's case get to work as quickly as possible. This makes the product more efficient and therefore more cost-effective per mg.*

It sounds like something out of a Science Fiction movie, but this incredible real-life science is safe, simple, and effective. The NanoZorb technology used in Cannabinoid Balance products is developed in an FDA registered facility, so consumers can rest assured that it is safe, effective and often more efficient than products that dont utilize this incredible technology.*

*The statements and products referred to by Cannabinoid Balance have not been evaluated by the FDA.

CBD Products Inc. is a multi-channel, CBD publishing and retail company established in 2018 that owns and operates cbdproducts.com, cbdworldnews.com and cbdpet.com. In the last year CBD Products Inc. has welcomed more than 25,000 people to their sites and offered information and resources across more than 100,000 page views.

CBD Products Inc. is also the owner of Cannabinoid Balance. A line of consumer products that includes Cannabinoid Balance Original+, Cannabinoid Balance Sleep+, Cannabinoid Balance CBD Gummies+, Cannabinoid Balance Pain Relief Cream and Cannabinoid Balance Pet+. These products are sold via http://www.cbdproducts.com and include proprietary NanoZorb Technology designed to make Cannabinoid Balance products more effective and efficient.

It was founded by Anthony Tribunella in 2018. Anthony has worked in all aspects of the industry from growing to production, to publishing and retailing. With more than a decade of experience in CBD and a passion to see the industry become organized and honest, Anthony is rapidly becoming a shining light, thought leader and conscience for the industry he cares so deeply about.

For more information on CBD Products Inc. please visit http://www.cbdproducts.com or email contact@cbdproducts.com.

Share article on social media or email:

Originally posted here:
The Tiny Technology Helping Cannabinoid Balance By CBD Products Inc. Make A Big Splash - PR Web

Nanotechnology in Drug Delivery Market 2020 To Witness High Growth In Near Future | Top Key Players Like Access Pharmaceuticals, Alkermes, Aquanova,…

Dataintelo, one of the worlds leading market research firms has rolled out a new report on Nanotechnology in Drug Delivery market. The report is integrated with crucial insights on the market which will support the clients to make the right business decisions. This research will help both existing and new aspirants for Global Nanotechnology in Drug Delivery Market to figure out and study market needs, market size, and competition. The report provides information about the supply and demand situation, the competitive scenario, and the challenges for market growth, market opportunities, and the threats faced by key players.

The report also includes the impact of the ongoing global crisis i.e. COVID-19 on the Nanotechnology in Drug Delivery market and what the future holds for it. The pandemic of Coronavirus (COVID-19) has landed a major blow to every aspect of life globally. This has lead to various changes in market conditions. The swiftly transforming market scenario and initial and future assessment of the impact are covered in the report.

Request a sample Report of Nanotechnology in Drug Delivery Market: https://dataintelo.com/request-sample/?reportId=101591

The report is fabricated by tracking the market performance since 2015 and is one of the most detailed reports. It also covers data varying according to region and country. The insights in the report are easy to understand and include pictorial representations. These insights are also applicable in real-time scenarios. Components such as market drivers, restraints, challenges, and opportunities for Nanotechnology in Drug Delivery are explained in detail. Since the research team is tracking the data for the market from 2015, therefore any additional data requirement can be easily fulfilled.

The scope of the report has a wide spectrum extending from market scenarios to comparative pricing between major players, cost, and profit of the specified market regions. The numerical data is supported by statistical tools such as SWOT analysis, BCG matrix, SCOT analysis, and PESTLE analysis. The statistics are depicted in a graphical format for a clear picture of facts and figures.

The generated report is strongly based on primary research, interviews with top executives, news sources, and information insiders. Secondary research techniques are utilized for better understanding and clarity for data analysis.

The Nanotechnology in Drug Delivery Market is divided into the following segments to have a better understanding:

By Application:

CancerTumorOther

By Type:

Targeted DeliveryDrug Package

By Geographical Regions:

Ask for Discount on Nanotechnology in Drug Delivery Market Report at: https://dataintelo.com/ask-for-discount/?reportId=101591

The Nanotechnology in Drug Delivery Market industry Analysis and Forecast 20192026 help clients with customized and syndicated reports holding key importance for professionals requiring data and market analytics. The report also calls for market-driven results providing feasibility studies for client requirements. Dataintelo promises qualified and verifiable aspects of market data operating in the real-time scenario. The analytical studies are carried out ensuring client requirements with a thorough understanding of market capacities in the real-time scenario.

Some of the prominent companies that are covered in this report:

Key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report. Following is the list of key players:

Access PharmaceuticalsAlkermesAquanovaCamurusCapsulution PharmaCelgene

*Note: Additional companies can be included on request

Reasons you should buy this report:

Dataintelo provides attractive discounts that fit your needs. Customization of the reports as per your requirement is also offered. Get in touch with our sales team, who will guarantee you a report that suits your needs.

Customized Report and Inquiry for the Nanotechnology in Drug Delivery Market Report: https://dataintelo.com/enquiry-before-buying/?reportId=101591

About US:

DATAINTELO has set its benchmark in the market research industry by providing syndicated and customized research report to the clients. The database of the company is updated on a daily basis to prompt the clients with the latest trends and in-depth analysis of the industry.

Our pool of database contains various industry verticals that include: IT & Telecom, Food Beverage, Automotive, Healthcare, Chemicals and Energy, Consumer foods, Food and beverages, and many more. Each and every report goes through the proper research methodology, validated from the professionals and analysts to ensure the eminent quality reports.

Contact US:

Name: Alex MathewsPhone No.: +1 909 545 6473Email: [emailprotected] Website: https://dataintelo.com Address: 500 East E Street, Ontario, CA 91764, United States.

More here:
Nanotechnology in Drug Delivery Market 2020 To Witness High Growth In Near Future | Top Key Players Like Access Pharmaceuticals, Alkermes, Aquanova,...

Researchers Use Charged Nanoscale MOFs and X-Rays to Kill Cancer Cells – AZoNano

Written by AZoNanoOct 5 2020

The heterogeneity of cancer cells themselves is one of the main difficulties faced in the development of effective and targeted treatments for cancer. This change makes it hard for the immune system to identify, react to, and actively fight against tumors.

But new advances in the field of nanotechnology are currently rendering it feasible to provide targeted and personalized vaccines to treat cancer.

A new study, reported recently in the Science Advances journal, describes the use of charged nanoscale metal-organic frameworks and X-rays to produce free radicals inside tumor tissue to directly destroy the cancer cells.

Moreover, it is possible to use the same frameworks to provide immune signaling molecules called PAMPs to trigger the immune response against tumor cells. By integrating these two methods into one vaccine that can be easily administered, this new technology could pave the way to improve local and systemic treatment of cancers that are hard to treat.

As part of a collaboration between the Lin Group from the Department of Chemistry at the University of Chicago and the Weichselbaum Lab at the University of Chicago Medicine, the researchers combined expertise from cancer biology and inorganic chemistry to address the challenging issue of correctly targeting and triggering an innate immune response against cancer.

This study took advantage of the special properties of nanoscale metal-organic frameworks (nMOFs), which are nanoscale structures made of recurring units arranged in a lattice formation and with the ability to infiltrate tumors.

Such nMOFs can be irradiated with the help of X-rays to produce high concentrations of free oxygen radicals, thereby directly killing the cancer cells and generating inflammatory molecules and antigens helping the immune system identify and clear cancerous cells, quite similar to a vaccine.

Moreover, the lattice-like structure of the nMOFs makes them ideal transporters to directly deliver anti-cancer drugs to tumors. But to date, it has been challenging to trigger innate and adaptive immune responses essential for destroying cancerous tumors.

As part of the new research, the team further refined their technique. They produced a new kind of nMOF structure that can be loaded with drugs called pathogen-associated molecular patterns (PAMPs).

Upon applying the nMOFs to cancerous tumors, irradiation of the tissue had a double impact: it activated the nMOFs to destroy local cancer cells to create antigens against the tumor and discharged the PAMPs, which subsequently triggered a much more powerful activation of the immune response to the tumor antigens.

This one-two punch could destroy both pancreatic and colon cancer cells with high efficacy, even in tumor models that are considerably resistant to other types of immunotherapy.

The investigators performed additional experiments with mice and observed that they could expand the impacts of the nMOFs even to distant tumors by applying checkpoint inhibitors, offering new hopes for treating cancer both systemically and locally with this method.

By including PAMP delivery with the nMOFs, this is the first time we were able to really enhance the immune response to the antigens. This is entirely different from all of our previous studies because weve shown that the nMOFs plus PAMPs can impact all of the aspects required for activating the immune system.

Wenbin Lin, PhD, Study Senior Author and James Franck Professor of Chemistry, University of Chicago Medical Center

We can use this nanoformulation to enable personalized cancer vaccinations that will work on any patient because this strategy will not be subject to the heterogeneity we see among different patients, added Lin.

The impacts of the treatment were so marked that the scientists are keen to bring the technology to clinical trials, whereas the other versions of the nMOF technology are already being tested, with encouraging results until now.

The brilliance of this system is twofold. First, it can improve local tumor control by increasing the killing power of X-rays. Second, while there has been interest in using radiation to stimulate the immune response to fight cancer, it has turned out to be harder than we thought.

Ralph Weichselbaum, MD, Study Co-Author and Daniel K. Ludwig Distinguished Service Professor of Radiation and Cellular Oncology, University of Chicago Medical Center

In this case, the nMOFs are able to activate the innate and adaptive immune systems, which makes this technology very promising for treating cancer in the clinic, added Weichselbaum, who is also the Chair of the Department of Radiation and Cellular Oncology at UChicago.

The investigators are already looking forward to next steps and striving to fine-tune the technology. Were refining the design of the nMOF and its delivery of the PAMPs, in preparation for testing it in humans, stated Lin. Were really working on zooming in on the best formulation so we can get this into clinical trials, hopefully in the next two to three years, or even sooner.

The researchers acknowledge the interdisciplinary and collaborative nature of UChicago and the University of Chicago Medicines Hyde Park campus for making a space where cancer biology and chemistry have combined to create such an encouraging potential therapy, as well as the support they have received from Ludwig Cancer Research along the way.

From the conception of this project and getting it funded to starting with clinical trials where were able to test the technology in clinical trials and get real patient data, this work has all been done right here at UChicago. We really are going from discovering something in the lab to testing it at the bedside.

Ralph Weichselbaum, MD, Study Co-Author and Daniel K. Ludwig Distinguished Service Professor of Radiation and Cellular Oncology, University of Chicago Medical Center

The study titled Nanoscale metal-organic frameworks for x-ray activated in situ cancer vaccination was financially supported by the National Cancer Institute (U01-CA198989 and 1R01CA253655), the Department of Defense (PC170934P2), the University of Chicago Medicine Comprehensive Cancer Center (NIH CCSG: P30 CA014599), and the Ludwig Institute for Metastasis Research.

The additional authors of the study are Kaiyuan Ni, Guangxu Lan, Nining Guo, August Culbert, Taokun Luo, and Tong Wu of the University of Chicago.

Ni, K., et al. (2020) Nanoscale metal-organic frameworks for x-ray activated in situ cancer vaccination. Science Advances. doi.org/10.1126/sciadv.abb5223.

Source: https://www.uchicagomedicine.org/

Continue reading here:
Researchers Use Charged Nanoscale MOFs and X-Rays to Kill Cancer Cells - AZoNano

COVID-19 Recovery Analysis: Global Particle Size Analyzer Market | Growing Applications of Nanotechnology to Boost Market Growth | Technavio -…

LONDON--(BUSINESS WIRE)--Technavio has been monitoring the global particle size analyzer market size and it is poised to grow by USD 94.95 million during 2020-2024, progressing at a CAGR of about 5% during the forecast period. The report offers an up-to-date analysis regarding the current market scenario, latest trends and drivers, and the overall market environment.

Although the COVID-19 pandemic continues to transform the growth of various industries, the immediate impact of the outbreak is varied. While a few industries will register a drop in demand, numerous others will continue to remain unscathed and show promising growth opportunities. Technavios in-depth research has all your needs covered as our research reports include all foreseeable market scenarios, including pre- & post-COVID-19 analysis. We offer $1000 worth of FREE customization

The market is fragmented, and the degree of fragmentation will accelerate during the forecast period. Agilent Technologies Inc., Anton Paar GmbH, Beckman Coulter Inc., FLSmidth & Co. A/S, HORIBA Ltd., Malvern Panalytical Ltd., Micromeritics Instrument Corp., Microtrac Retsch GmbH, Shimadzu Corp., and TSI Inc. are some of the major market participants. To make the most of the opportunities, market vendors should focus more on the growth prospects in the fast-growing segments, while maintaining their positions in the slow-growing segments.

Buy 1 Technavio report and get the second for 50% off. Buy 2 Technavio reports and get the third for free.

View market snapshot before purchasing

Growing applications of nanotechnology have been instrumental in driving the growth of the market. However, the high overall expense might hamper the market growth.

Technavio's custom research reports offer detailed insights on the impact of COVID-19 at an industry level, a regional level, and subsequent supply chain operations. This customized report will also help clients keep up with new product launches in direct & indirect COVID-19 related markets, upcoming vaccines and pipeline analysis, and significant developments in vendor operations and government regulations. Download a Free Sample Report on COVID-19 Impacts

Particle Size Analyzer Market 2020-2024: Segmentation

Particle Size Analyzer Market is segmented as below:

Particle Size Analyzer Market 2020-2024: Scope

Technavio presents a detailed picture of the market by the way of study, synthesis, and summation of data from multiple sources. The particle size analyzer market report covers the following areas:

This study identifies the growing applications in the pharmaceutical industry as one of the prime reasons driving the Particle Size Analyzer Market growth during the next few years.

Technavio suggests three forecast scenarios (optimistic, probable, and pessimistic) considering the impact of COVID-19. Technavios in-depth research has direct and indirect COVID-19 impacted market research reports.

Register for a free trial today and gain instant access to 17,000+ market research reports.

Technavio's SUBSCRIPTION platform

Particle Size Analyzer Market 2020-2024: Key Highlights

Table of Contents:

Executive Summary

Market Landscape

Market Sizing

Five Forces Analysis

Market Segmentation by Technology

Market Segmentation by End-user

Customer landscape

Geographic Landscape

Vendor Landscape

Vendor Analysis

Appendix

About Us

Technavio is a leading global technology research and advisory company. Their research and analysis focus on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavios report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavios comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios.

Continue reading here:
COVID-19 Recovery Analysis: Global Particle Size Analyzer Market | Growing Applications of Nanotechnology to Boost Market Growth | Technavio -...

Nanotechnology in Medical Devices Market 2020-2027 Incredible Possibilities, Growth With Industry Study, Detailed Analysis || Leading Players 3M,…

The large scale Nanotechnology in Medical Devices marketing report provides CAGR values along with its fluctuations for the specific forecast period. This persuasive marketing report has been generated by taking into thought several aspects of marketing research and analysis that can be listed as market size estimations, market dynamics, company & market best practices, entry level marketing strategies, positioning and segmentations, competitive landscaping, opportunity analysis, economic forecasting, industry-specific technology solutions, roadmap analysis, targeting key buying criteria & in-depth benchmarking of vendor offerings. This Nanotechnology in Medical Devices market research report is of great importance for superior decision making and achieving competitive advantage.

Get Sample PDF (including COVID19 Impact Analysis) of Market Report @https://www.databridgemarketresearch.com/request-a-sample/?dbmr=global-nanotechnology-in-medical-devices-market&rp

Market Analysis and Insights of Global Nanotechnology in Medical Devices Market

Nanotechnology in medical devices market is expected to reach a market value of USD 20.52 billion by 2027 growing with the CAGR of 11.9% in the forecast period of 2020-2027. The increasing support of the government in the provision on advanced technology has been directly impacting the growth of nanotechnology in medical devices market.

The major players covered in thenanotechnology in medical devices marketreport are3M, Dentsply Sirona., Thermo Fisher Scientific Inc., PerkinElmer Inc, GENERAL ELECTRIC, Ferro Corporation, Eppendorf AG, Greiner Bio One International GmbH, ZELLMECHANIK DRESDEN, TV Rheinland, Medtronic, Boston Scientific Corporation, BIOTRONIK SE & Co. KG, LivaNova PLC, Demant A/S, Cochlear Ltd., Sonova, MED-EL, DEKRA, among other domestic and global players.Market share data is available for Global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.

Get Full TOC, Tables and Figures of Market Report @https://www.databridgemarketresearch.com/toc/?dbmr=global-nanotechnology-in-medical-devices-market&rp

Increasing geriatric population along with rising occurrences of diseases across the globe and growing adoption and need of high and advanced technology for the treatment of chronic diseases will accelerate the growth of the nanotechnology in medical devices market in the forecast period of 20202-2027. Rising number of applications from the emerging countries and advancement to technology for rich mid to late stage product pipeline will further create new opportunities for the growth of the market in the above mentioned forecast period.

Strict rules and regulations that will consume time in product approval and increasing process of nanotechnology based medical devices will hamper the growth of the market in the forecast period of 2020-2027.

This nanotechnology in medical devices market report provides details of new recent developments, trade regulations, import export analysis, production analysis, value chain optimization, market share, impact of domestic and localised market players, analyses opportunities in terms of emerging revenue pockets, changes in market regulations, strategic market growth analysis, market size, category market growths, application niches and dominance, product approvals, product launches, geographical expansions, technological innovations in the market. To gain more info onData Bridge Market Researchnanotechnology in medical devices market contact us for anAnalyst Brief, our team will help you take an informed market decision to achieve market growth.

Global Nanotechnology in Medical Devices Market Scope and Market Size

Nanotechnology in medical devices market is segmented on the basis of product and application. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.

Nanotechnology in Medical Devices Market Country Level Analysis

Nanotechnology in medical devices market is analysed and market size insights and trends are provided by country, product and application as referenced above.

The countries covered in the nanotechnology in medical devices market report are U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.

North America dominates the nanotechnology in medical devices market because of prevalence of majority of nanotechnology based medical devices players and increasing government initiatives, while Asia-Pacific is expected to grow at the highest growth rate in the forecast period of 2020 to 2027 because of increasing geriatric population, international research collaboration and increasing investment in research and development of nanotechnology.

The country section of the nanotechnology in medical devices market report also provides individual market impacting factors and changes in regulation in the market domestically that impacts the current and future trends of the market. Data points such as consumption volumes, production sites and volumes, import export analysis, price trend analysis, cost of raw materials, down-stream and upstream value chain analysis are some of the major pointers used to forecast the market scenario for individual countries. Also, presence and availability of global brands and their challenges faced due to large or scarce competition from local and domestic brands, impact of domestic tariffs and trade routes are considered while providing forecast analysis of the country data.

Healthcare Infrastructure Growth Installed Base and New Technology Penetration

Nanotechnology in medical devices market also provides you with detailed market analysis for every country growth in healthcare expenditure for capital equipment, installed base of different kind of products for nanotechnology in medical devices market, impact of technology using life line curves and changes in healthcare regulatory scenarios and their impact on the nanotechnology in medical devices market. The data is available for historic period 2010 to 2018.

Competitive Landscape and Nanotechnology in Medical Devices Market Share Analysis

Nanotechnology in medical devices market competitive landscape provides details by competitor. Details included are company overview, company financials, revenue generated, market potential, investment in research and development, new market initiatives, global presence, production sites and facilities, production capacities, company strengths and weaknesses, product launch, product width and breadth, application dominance. The above data points provided are only related to the companies focus related to nanotechnology in medical devices market.

Customization Available : Global Nanotechnology in Medical Devices Market

Data Bridge Market Research is a leader in advanced formative research. We take pride in servicing our existing and new customers with data and analysis that match and suits their goal. The report can be customised to include price trend analysis of target brands understanding the market for additional countries (ask for the list of countries), clinical trial results data, literature review, refurbished market and product base analysis. Market analysis of target competitors can be analysed from technology-based analysis to market portfolio strategies. We can add as many competitors that you require data about in the format and data style you are looking for. Our team of analysts can also provide you data in crude raw excel files pivot tables (Factbook) or can assist you in creating presentations from the data sets available in the report.

Do You Have Any Query Or Specific Requirement? Ask to Our Industry Expert @https://www.databridgemarketresearch.com/inquire-before-buying/?dbmr=global-nanotechnology-in-medical-devices-market&rp

About Data Bridge Market Research:

Data Bridge Market Researchis a versatile market research and consulting firm with over 500 analysts working in different industries. We have catered more than 40% of the fortune 500 companies globally and have a network of more than 5000+ clientele around the globe. Our coverage of industries include Medical Devices, Pharmaceuticals, Biotechnology, Semiconductors, Machinery, Information and Communication Technology, Automobiles and Automotive, Chemical and Material, Packaging, Food and Beverages, Cosmetics, Specialty Chemicals, Fast Moving Consumer Goods, Robotics, among many others.

Data Bridge adepts in creating satisfied clients who reckon upon our services and rely on our hard work with certitude.We are content with our glorious 99.9 % client satisfying rate.

Contact Us :

Data Bridge Market Research

US: +1 888 387 2818

UK: +44 208 089 1725

Hong Kong: +852 8192 7475Mail:Corporatesales@databridgemarketresearch.com

Visit link:
Nanotechnology in Medical Devices Market 2020-2027 Incredible Possibilities, Growth With Industry Study, Detailed Analysis || Leading Players 3M,...

Medtronic Announces Adaptix Interbody System, the First Navigated Titanium Cage with Titan nanoLOCK Surface Technology – BioSpace

A World's First That Combines Innovative Technologies: Titan nanoLOCK Surface Technology and Navigation

DUBLIN, Oct. 7, 2020 /PRNewswire/ -- Medtronic plc (NYSE:MDT), the global leader in medical technology, today announced the U.S. launch of Adaptix Interbody System, the first navigated titanium implant with Titan nanoLOCK Surface Technology, a proprietary blend of surface textures on the macro, micro, and nano levels. The Adaptix Interbody System, mirrored after the veteran Capstone Spinal System, touts improved features for increased strength,1 subsidence resistance,1,2,3 easy insertion, and data-backed bone growth4,5. The announcement was made during the virtual edition of the North American Spine Society (NASS) annual meeting. Adaptix received U.S. Food and Drug Administration (FDA) approval in August 2020.

This milestone represents the first 3D printed titanium implant, developed in house by Medtronic engineers, that incorporates the state-of-the-art Titan nanoLOCK Surface Technology.

Titan Spine, acquired in 2019, pioneered this surface technology that is the first to demonstrate the elements to be considered a nanotechnology for spinal devices as outlined in the FDA nanotechnology guidance document. Interbody implants are spacers that surgeons may insert between the vertebrae during spinal fusion surgery to help relieve pressure on nerves and hold the vertebrae in place while fusion occurs.

"Adaptix Interbody System allows me the best chance to meet my patients' needs by confidently placing the implant under navigation and trusting the Titan nanoLOCK Surface Technology to allow the implant to promote fusion. Surface technology, material type, and implant design all play a role in bone growth process during fusion," said J. Justin Seale, M.D. of OrthoArkansas Spine Institute. "The unique features and world-class technologies make the Adaptix Interbody System a truly differentiated implant."

The Adaptix Interbody System addresses surgeons' universal needs of fusion outcomes and offers:

Medtronic continues to transform spine care and deliver on its Surgical Synergy strategy by offering solutions that integrate implants, biologics, and enabling technologies. Adaptix Interbody System is compatible with the Medtronic navigation platform (StealthStation Navigation and O-arm imaging) and the newly released Grafton DBF Inject, a unique graft delivery syringe that delivers an osteoinductive6 DBM into the surgical site.

"Adaptix Interbody System is an exciting addition to our portfolio that leads with our Titan nanoLOCK Surface Technology," said Sharrolyn Josse, vice president and general manager of Medtronic Core Spine and Biologics division, which is part of the Restorative Therapies Group at Medtronic. "It is a fully navigated procedure, leveraging our leadership in navigation."

About MedtronicMedtronic plc (www.medtronic.com), headquartered in Dublin, Ireland, is among the world's largest medical technology, services and solutions companies alleviating pain, restoring health and extending life for millions of people around the world. Medtronic employs more than 90,000 people worldwide, serving physicians, hospitals and patients in more than 150 countries. The company is focused on collaborating with stakeholders around the world to take healthcare Further, Together.

Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic's periodic reports on file with the Securities and Exchange Commission. Actual results may differ materially from anticipated results.

1 Comparison of Adaptix and Capstone testing per ASTM F2077and ASTM F2267.2 Based on surface area measurement.3 Based on engineering principles.4 Wennerberg, A., & Albrektsson, T. (2009). Effects of titanium surface topography on bone integration: a systematic review. Clin Oral Implants Res, 20 Suppl 4, 172-184.5 Gittens, R.A., Olivares-Navarrete, R., Schwartz, Z, Boyan, B.D. (2014). Implant osseointegration and the role of microroughness and nanostructures: lessons for spine implants. Acta Biomater., 10(8), 3363-71.6 Data on file. Animal data is not necessarily indicative of human clinical outcomes.

Contacts:

Victor Rocha

Ryan Weispfenning

Public Relations

Investor Relations

+1-901-399-2401

+1-763-505-4626

View original content to download multimedia:http://www.prnewswire.com/news-releases/medtronic-announces-adaptix-interbody-system-the-first-navigated-titanium-cage-with-titan-nanolock-surface-technology-301147250.html

SOURCE Medtronic plc

Company Codes: NYSE:MDT

Read the original here:
Medtronic Announces Adaptix Interbody System, the First Navigated Titanium Cage with Titan nanoLOCK Surface Technology - BioSpace

Nanotechnology In Medical Applications Market: Which Region Will Register Higher CAGR? 2022 – Amazing Facts

Theglobal nanomedical marketwas valued at $134.4 billion in 2016. This market is projected to grow at a compound annual growth rate (CAGR) of 14.0% from 2017-2022, and should reach $293.1 billion by 2022 from $151.9 billion in 2017.

Get PDF Sample Copy of this Report to understand the structure of the complete report: (Including Full TOC, List of Tables & Figures, Chart) @https://www.trendsmarketresearch.com/report/sample/12261

Report Scope:

This report discusses the implications of technology and commercial trends in the context of the current size and growth of the pharmaceutical market, both in global terms and analyzed by the most important national markets. The important technologies supporting nanomedicine are reviewed, and the nature and structure of the nanomedicine industry are discussed with profiles of the leading 60+ companies, including recent merger and acquisition (M&A) activity. Five-year sales forecasts are provided for the national markets including the major therapeutic categories of products involved. Specific product categories quantified include diagnostics, cancer, CNS, anti-infective agents, cardiovasculars and anti-inflammatories.

Report Includes:

An overview of the global markets for nanotechnology used in medical applications Analyses of global market trends, with data from 2016, estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022 A review of technologies involved, in-depth analysis of applications in practice, and evaluation of future or potential applications Information on many significant products in which the nano dimension has made a significant contribution to product effectiveness A look at the regulatory environment, healthcare policies, demographics, and other factors that directly affect nanotechnology used in medicine Analysis of the markets dynamics, specifically growth drivers, inhibitors, and opportunities Coverage of strategies employed by companies specializing in nanomedicine to meet the challenges of this highly competitive market

Summary

Nano-enabled medical products began appearing on the market over a decade ago, and some have become best-sellers in their therapeutic categories. The principal areas in which nanomedical products have made an impact are cancer, CNS diseases, cardiovascular disease and infection control. The Summary Table gives estimates of the historical and current markets for these nanomedicine areas with a forecast through 2022.

The U.S. market is by far the largest in the global nanomedicine market and is set to continue to dominate the world marketplace; however, other national markets are expected to increase their shares over the next five years.

<<< Get COVID-19 Report Analysis >>>https://www.trendsmarketresearch.com/report/covid-19-analysis/12261

Reasons for Doing the Study

Nanomedicine is already an established market. Unlike some other potential applications of nanotechnology, which are still largely experimental, nanomedicine has already produced some significant products in which the nano dimension has made a significant contribution to product effectiveness. Now that aspects of the nanomedicine market are established, it is appropriate to review the technology, see its practical applications so far, evaluate the participating companies and look to its future.

Link:
Nanotechnology In Medical Applications Market: Which Region Will Register Higher CAGR? 2022 - Amazing Facts

Aerospace Nanotechnology Market Trends, Industry Size, Growth, Analysis and Forecast 2028 – The Daily Chronicle

Market Scenario of the Aerospace Nanotechnology Market:

The most recent Aerospace Nanotechnology Market Research study includes some significant activities of the current market size for the worldwide Aerospace Nanotechnology market. It presents a point by point analysis dependent on the exhaustive research of the market elements like market size, development situation, potential opportunities, and operation landscape and trend analysis. This report centers around the Aerospace Nanotechnology-business status, presents volume and worth, key market, product type, consumers, regions, and key players.

Sample Copy of This Report @ https://www.quincemarketinsights.com/request-sample-62977?utm_source=TDC/komal

The prominent players covered in this report: Airbus, Glonatech, Flight Shield, Lockheed Martin, Lufthansa Technik, tripleO Performance Solution, Zyvex Technologies, CHOOSE NanoTech, General Nano, HR TOUGHGUARD, Metamaterial Technologies.

The market is segmented into By Product Type (Nanomaterials, Nanotools, Nanodevices), By End User (Aircraft Parts, Fuselage Structure, Aero Engine Parts, Aircraft Electronic Communication System, Other).

Geographical segments are North America, Europe, Asia Pacific, Middle East & Africa, and South America.

A 360 degree outline of the competitive scenario of the Global Aerospace Nanotechnology Market is presented by Quince Market Insights. It has a massive data allied to the recent product and technological developments in the markets.

It has a wide-ranging analysis of the impact of these advancements on the markets future growth, wide-ranging analysis of these extensions on the markets future growth. The research report studies the market in a detailed manner by explaining the key facets of the market that are foreseeable to have a countable stimulus on its developing extrapolations over the forecast period.

Get ToC for the overview of the premium report @ https://www.quincemarketinsights.com/request-toc-62977?utm_source=TDC/komal

This is anticipated to drive the Global Aerospace Nanotechnology Market over the forecast period. This research report covers the market landscape and its progress prospects in the near future. After studying key companies, the report focuses on the new entrants contributing to the growth of the market. Most companies in the Global Aerospace Nanotechnology Market are currently adopting new technological trends in the market.

Finally, the researchers throw light on different ways to discover the strengths, weaknesses, opportunities, and threats affecting the growth of the Global Aerospace Nanotechnology Market. The feasibility of the new report is also measured in this research report.

Reasons for buying this report:

Make an Enquiry for purchasing this Report @ https://www.quincemarketinsights.com/enquiry-before-buying/enquiry-before-buying-62977?utm_source=TDC/komal

About Us:

QMI has the most comprehensive collection of market research products and services available on the web. We deliver reports from virtually all major publications and refresh our list regularly to provide you with immediate online access to the worlds most extensive and up-to-date archive of professional insights into global markets, companies, goods, and patterns.

Contact Us:

Quince Market Insights

Ajay D. (Knowledge Partner)

Office No- A109

Pune, Maharashtra 411028

Phone: APAC +91 706 672 4848 / US +1 208 405 2835 / UK +44 1444 39 0986

Email: [emailprotected]

Web: https://www.quincemarketinsights.com

Continue reading here:
Aerospace Nanotechnology Market Trends, Industry Size, Growth, Analysis and Forecast 2028 - The Daily Chronicle

CBD Technologies: What Should We Expect in the Near Future? – TechDay News

CBD has been a buzzword around the health and wellness, and beauty industries for years. The promise of having a plant-derived product that offers a myriad benefits with nearly none of the side effects is something that is too good to just pass by. Because of its unique way of binding with our bodys endocannabinoid system (ECS), the fact that cannabinoids also occur inside our bodies naturally, and the largely still unexplored positive effects of cannabinoids to our health, many scientists, researchers, and even the tech industry has conducted many studies to understand CBD and come up with better ways to increase its bioavailability in our bodies.

CBD and technology their possible future

More controlled CBD levels

Researchers and scientists have come up with methods in breeding plants with higher CBD levels and near non-existent THC levels. The reason behind this is that THC, at certain levels, are still largely illegal. Whereas CBD has been deemed legal by the federal government.

Because of this, producers have been growing hemp plants with more control over the CBD levels of their yield. This means that in the near future, more growers will be able to produce plants that will yield more CBD, reducing waste and coming up with better quality products.

CBD and genetics

Some scientists have even been studying a persons genetics and the effects of CBD in relation to a persons DNA. Everyone responds to cannabis differently. In the future, we might see CBD products tailor made for your genetics, making your CBD treatment more effective.

Advances in extraction methods

Large strides have been made in extracting CBD from hemp plants. Where ethanol, butane, and acetone were once widely used to extract CBD, advances in the extraction field have come up with safer ways of extracting CBD that we can now largely do away with using hydrocarbons. Studies have found that using hydrocarbons could introduce carcinogenic compounds into the crude extract from hemp plants.

Safer and more efficient and environmentally friendly ways of extraction (i.e. Supercritical CO2 Extraction method, considered the gold standard in extraction) result in better quality CBD oil extracted from plants. We have been seeing safer and better quality CBD products become more prevalent in the market. In the future, we could be expecting more of these products and perhaps at a cheaper price once more producers apply the gold standard in extraction.

Nanotechnology

Scientists and researchers have been looking for ways to improve bioavailability in CBD products. Bioavailability is the amount of CBD that makes it into your bloodstream. The better the bioavailability of a CBD product is, the more efficient it is in providing treatment. Scientists have looked to nanotechnology to achieve this. Water-soluble CBD oils have been marketed by companies. These are being touted as a better, more efficient alternative to the regular CBD oils in the market. Though these water-soluble CBD oils are not really water-soluble, they do contain CBD molecules shrunk to nano-size to make them penetrate membranes more efficiently. This ensures that more CBD molecules will enter the bloodstream, therefore increasing its bioavailability. More studies need to be conducted regarding this but so far, the results from what studies have been made are generally positive. We may be seeing more of these nano-fied products in the market in the near future.

Conclusion

The future is looking bright for the CBD industry. With all the technological advances in the field, we can expect better, safer, and more efficient products in the future. And with numerous studies being conducted, perhaps we might even discover more ways that CBD can help treat various diseases.

Excerpt from:
CBD Technologies: What Should We Expect in the Near Future? - TechDay News

Aging-US Releases "From Causes of Aging to Death from COVID-19" – PRNewswire

Age, Age-related diseases, Male Gender, Mortality from aging compared with COVID-19 mortality, Age-related diseases, Cytokine storm as a hyperfunction, Hyperfunction theory of quasi-programmed aging, COVID-19 vulnerability as an age-related syndrome, Inflamm-aging and immunosenescence, Cellular senescence as a continuation of growth, Figuratively, rapamycin rejuvenates immunity, Anti-aging medicine, Rapamycin and everolimus as anti-aging drugs and, Potential applications of rapamycin/everolimus to COVID-19

The author contends that at its deepest level, aging is driven by inappropriately high cellular functioning. The hyperfunction theory of quasi-programmed aging explains why COVID-19 vulnerability is an age-dependent syndrome, linking it to other age-related diseases.

These conditions are typical age-related diseases: hypertension, diabetes, obesity, ischemic heart disease, chronic obstructive pulmonary disease, and other diseases.

This is because pre-existing conditions are manifestations of biological age, ultimately meaning that A. aging and B. diseases are two sides of the same coin.

The Blagosklonny Research Teamgoes on to highlight that an anti-aging intervention, such as rapamycin, may slow aging and age-related diseases, potentially decreasing COVID-19 vulnerability.

The Aging-US Reviewalso reported that as soon as the COVID-19 epidemic started, it became clear that COVID-19 vulnerability is an aging-dependent condition, and the use of rapamycin was immediately suggested by independent researchers.

By decreasing biological age and preventing age-related diseases, long-term rapamycin therapy may, in theory, decrease the COVID-19 mortality rate in the elderly.

As specifically discussed in the Review section titled "Figuratively, rapamycin rejuvenates immunity", mTOR inhibitors can improve immunity to viral infections, improve immunization and vaccination to some viruses such as the flu.

The hypothetical graph in the absence of COVID-19. COVID-19 vulnerability increases exponentially with age.

Then as discussed in the section "Cytokine storm is a hyperfunction", cytokine storm and hyper-inflammation is the main cause of death in COVID-19 pneumonia Rapamycin, an anti-inflammatory agent, inhibits hyper-functions, cellular senescence and decrease secretion of cytokines.

DOI- https://doi.org/10.18632/aging.103493

Full text- https://www.aging-us.com/article/103493/text#fulltext

Video-https://youtu.be/c6P8Kaw0qmw

Correspondence to- Mikhail V. Blagosklonny [emailprotected] or [emailprotected]

About Aging-US

Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research as well as topics beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, cancer, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR among others), and approaches to modulating these signaling pathways.

To learn more about Aging-US, please visithttp://www.Aging-US.comor connect with @AgingJrnl

Aging-US is published by Impact Journals, LLC please visit http://www.ImpactJournals.comor connect with @ImpactJrnls

Press Contact: Impact Journals +1 202-638-9720

SOURCE Aging-US

View post:
Aging-US Releases "From Causes of Aging to Death from COVID-19" - PRNewswire

The Underrated Anti-Inflammatory Nutrient That Will Help You Live Longer, According to a Functional Medicine Doctor – Well+Good

As one of the top functional medicine doctors in the country, Frank Lipman, MD, is asked a wide range of health-related questions every single day. Sometimes theyre tied to something specific trending in the wellness space: Is collagen overrated? (Nope.) Is oat milk? (Possibly.) Other times, its about how to get a better nights sleep. But all the queries seem to be rooted in an even bigger question: how to live a long, healthy life.

Longevity seems to be at the heart of every question hes asked, so Dr. Lipman decided to write a whole book dedicated to the topic: The New Rules of Aging Well: A Simple Program For Immunity Resilience, Strength, and Vitality ($20), out October 27, 2020. Tucked in the pages are some rules youre likely familiar with, like cutting back on sugar and having a strong sense of purpose. But there are also some surprising things that have been scientifically linked to longevity that arent as widely talked about. One of those truth bombs is centered around an anti-inflammatory compound called quercetin.

Never heard of it? Quercetin is a polyphenol derived in plants that is connected to lowering inflammation, supporting the immune system, and, yes, longevity. Besides curcumin, quercetin is one of the most important supplements for both immunity and longevity, Dr. Lipman says. Looks like turmeric has some competition.

Before we dig deep into all the benefits quercetin boasts, its helpful to know what the heck it actually is. Dr. Lipman explains that quercetin is a type of polyphenol, which are micronutrients with antioxidant properties found in plants. Some foods that have this particular type of polyphenol are apples, onion, raspberries, red grapes, and cherries.

Quercetin has lots of benefits, but Dr. Lipman is most excited about its connection with longevity.One is that it affects longevity gene pathways in a positive way, specifically activating AMPK [a protein enzyme], he says. AMPK helps regulate cellular metabolism; when cellular energy is low, AMPK is called in for backup to keep the body running as it should. It also controls cellular autophagy, aka the clearing out of damaged cells. And recent research suggests that the enzyme can potentially delay the aging process as well. One paper published in the journal Discoveries states that AMPK activation increased the life of fruit flies by as much as 30 percent.

Quercetin is anti-inflammatory, anti-viral, and immunity-boosting, Dr. Lipman addsproperties that are important for longevity. To his point, chronic inflammation is associated with many age-related health problems, including cognitive decline and cancer, so managing inflammation is often seen as crucial for living a longer, healthier life. Meanwhile, the immune system weakens with age, making it harder for the body to fight off illness, so keeping it in tip-top shape is critical. Quercetin also supports gut health; since a huge portion of the immune system lies in the gut, keeping your gut healthy is very important to immunity, says Dr. Lipman.

Dont worry curcumin, we still love you. Watch the video below to see why its so powerful:

Despite quercetin being in such a wide range of plant-based foods, Dr. Lipman says most people dont consume enough of it to truly benefit. Part of this is because most Americans dont eat enough fruits and vegetables, but even foods that naturally contain quercetin dont have very high doses of the polyphenol. This is why Dr. Lipman often recommends a quercetin supplement. (He actually has his own, Superpowder, $54, which he created for The Well as its chief medical officer.)

While certainly more studies need to be done on quercetin (particularly on humans, not fruit flies or rats), the evidence that suggests its connection to longevity is compelling. But Dr. Lipman reiterates that it, like anything else, certainly isnt a silver bullet for being a healthy octogenarian.

One of the most important things for longevity is getting enough sleep, he says. We have a glymphatic system in the brain, which is the brains self-cleaning mechanism, and it only works when youre asleep. Not getting enough sleep makes it harder for the glymphatic system to do its clean-up job, which over time can lead to cognitive decline, Dr. Lipman says.

He also emphasizes the importance of having a sense of purpose, regular exercise, and eating healthy overall. Doubling down on apples and onions or popping a daily quercetin supplement is no replacement for a healthy diet. When you look at Blue Zones, where people regularly live into old age in good health, they eat foods that are close to nature and not overly processed, they have a good support system, and aging is actually revered, Dr. Lipman says. These things matter.

When it comes to longevity, its not only about what you put into your body, but is also about whats in your heart. While the benefits may be outward-facing, when you get down to it, longevity truly is an inside job.

Oh hi! You look like someone who loves free workouts, discounts for cult-fave wellness brands, and exclusive Well+Good content. Sign up for Well+, our online community of wellness insiders, and unlock your rewards instantly.

Here is the original post:
The Underrated Anti-Inflammatory Nutrient That Will Help You Live Longer, According to a Functional Medicine Doctor - Well+Good

The anti-aging and skin-healing effects of vitamin E – Insider – INSIDER

Vitamin E is a fat-soluble vitamin that is found in foods like avocados, sunflower oil, and red bell peppers. When consumed orally, vitamin E has many benefits, including slowing the aging process of cells, boosting the immune system, and reducing premenstrual symptoms (PMC).

But for skin, vitamin E's main strength is its power as an antioxidant. Antioxidants help combat free radicals, which are unstable molecules that age our skin and damage cells.

While there are many proven benefits of vitamin E for skin health, there are also some myths that lack evidence. Here's what you need to know.

Vitamin E, in particular, is a potent antioxidant that can prevent sun damage to the skin, alleviate eczema, and more.

Free radicals are everywhere. They can be emitted from the sun, pollution, cigarette smoke, and a vast number of other sources. They show up naturally in our bodies, too. These unstable molecules can damage collagen and glycosaminoglycans, two substances that keep your skin smooth, firm, and moisturized.

Since vitamin E is a strong antioxidant, it can combat the effects of free radicals on your skin and protect it from visible signs of aging caused by these damaging molecules.

How to use it: You can use it topically and it is available in an cream, oil, or serum.

Free radicals from the sun can cause collagen and elastin in the skin to breakdown, which can trigger signs of aging like fine lines and wrinkles. Since vitamin E has antioxidant properties, it can help fight signs of sun damage, says Caren Campbell, MD, a board-certified dermatologist with a private practice in San Francisco.

Additionally, using vitamin E in combination with vitamin C in topical formulations, like creams or serums, has been shown to prevent short term UV damage as well as chronic UV photodamage, like dark spots.

How to use it: To use vitamin E to fight sun damage, use it topically in creams, oils, or serums. Even though it may be able to prevent UV damage, it won't replace sunscreen.

One small 2015 study found that taking vitamin E supplements of 400 IU/day for four months was more effective at treating eczema symptoms including itching and lesions than a placebo.

However, more thorough research is needed before healthcare professionals should consider prescribing a vitamin E supplement to treat eczema, says Kathleen C. Suozzi, MD, dermatologist and aesthetics director of Yale Medicine Dermatology.

How to use it: To use vitamin E for eczema, consider taking it orally through a supplement. However, you should check with your doctor before starting any supplements, as Vitamin E can build up in the body to dangerous amounts if you regularly take too much.

Studies have shown that vitamin E may be helpful for psoriasis, however, these studies have not looked at vitamin E on its own.

One 2009 study looked at the supplementation of coenzyme Q10, vitamin E, and selenium in 58 patients with severe psoriasis. The study found that oxidative stress was reduced and clinical conditions of psoriasis were improved in patients who took the supplements versus those who took a placebo.

How to use it: More research needs to be done to confirm the efficacy of using vitamin E alone, but to use vitamin E for psoriasis, you can take it in the form of supplements. Again, check with your doctor before taking supplements.

There are also many unfounded claims about how vitamin E affects the skin:

Some people believe that vitamin E can help reduce scarring from wounds and acne. However, research has shown that topical application of Vitamin E to scars does not make a difference in the appearance of the scars, and may actually result in contact dermatitis.

There is anecdotal evidence that topical vitamin E can help prevent or reduce the appearance of stretch marks. Studies have not backed this up, though. According to the American Academy of Dermatology Association, home remedies such as vitamin E for stretch marks are not effective.

The antioxidant properties of vitamin E could possibly make it useful for skin cancer prevention, says the Skin Cancer Foundation. However, hard research supporting this is weak, and it is best to use proven means of preventing skin cancer, like always using sunscreen.

Vitamin E isn't for everybody. Suozzi says that patients with sensitive skin may have negative reactions to topical vitamin E.

Additionally, those with eczema-prone skin may have bad reactions to topical vitamin E, so if you plan on using the vitamin for eczema, it's best to stick to consuming it orally.

Campbell also says that you should be cautious if you are taking vitamin E supplements. She says an excessive intake of vitamin E can cause GI side effects like:

Additionally, vitamin E reduces blood clotting, so Campbell says it can increase your risk of bleeding or bruising. She says you should definitely avoid taking it before any medical procedures.

Since scientific evidence is spotty for vitamin E in skincare, it may be best to consult your dermatologist before trying it out orally or topically.

A dermatologist can tell you if vitamin E is the right choice for you and whatever skin ailment you may be trying to treat, as well as how to use it safely.

Original post:
The anti-aging and skin-healing effects of vitamin E - Insider - INSIDER

Avoid these 5 foods to improve your arthritis symptoms – Atlanta Journal Constitution

Inflammatory fats

While you may enjoy burgers, steaks and fried foods, these kinds of meals arent ideal for people with arthritis and should be avoided according to the Arthritis Foundation. Omega 6 fatty acids, which along with saturated fats are found in meats and fried foods, as well as trans fats found in fast food items and bakery products, can go against an anti-inflammatory diet.

There is accumulating evidence that diet certainly impacts whether our body has an inflammatory environment versus an anti-inflammatory environment, Melinda Ring, M.D., executive director of the Osher Center for Integrative Medicine at Northwestern University and clinical associate professor at the Northwestern University Feinberg School of Medicine told Self magazine.

Sugar

A 2018 study published in the journal Arthritis Care & Research found that sugar-laden soda and desserts were most frequently stated as dietary items that worsened RA symptoms. But sugar is not just in soda and sweets. Hidden sugars can be found in seemingly healthy items such as granola bars and yogurt, according to WebMD.

Gluten

Gluten-free diets have increased in popularity over the last few years, but while it may be a fad for some, it could be a worthwhile change for people with arthritis. In a randomized study published in The Open Rheumatology Journal in 2018, 66 patients with RA who took on a gluten-free, vegan diet showed possible anti-inflammatory changes as well as those that protected against the build-up of fats in the arteries.

Nightshades vegetables

If you enjoy bell peppers in your salad but notice it aggravates your symptoms, you might want to consider giving them up.

Bell peppers, chilli peppers, eggplants, potatoes and tomatoes are among the vegetables that contain solanine, which according to the Arthritis Foundation is a chemical some people anecdotally state can exacerbate their symptoms. Still, rheumatologist/immunologist Leonard Calabrese told Cleveland Clinic it is highly unlikely that avoiding the trace amounts of solanine found in nightshade vegetables will ease your arthritic pain or inflammation. Research to support this claim just isnt there.

Purines-containing foods

If you suffer from gout, also known as gouty arthritis, there are certain foods that can be limited in your diet to reduce the severe pain and tenderness that occurs in the joints. This happens when uric acid builds up in the bloodstream and causes a gout attack. Since foods including organ meats, red meat and seafood like shellfish can contain high amounts of purines, they should be restricted in the diet. Purines convert to uric acid in the body, leading to symptoms of gout. According to the Mayo Clinic, following a diet that involves these measures may lower the risk of recurring gout attacks and slow the progression of joint damage.

Continued here:
Avoid these 5 foods to improve your arthritis symptoms - Atlanta Journal Constitution