Nanotechnology in Medical Market Emerging Trends and Capture Significant Growth by 2027 With Worldwide Top Most Players: Jude Medical Inc. (US),…

Nanotechnology in Medical Market has witnessed continuous growth within the past few years and is projected to grow even more throughout the forecast period (2020 2027). The analysis presents a whole assessment of the market and contains Future trends, Current Growth Factors, attentive opinions, facts, historical information, and statistically supported and trade valid market information.

The report, titled Global Nanotechnology in Medical Market defines and briefs readers about its products, applications, and specifications. The research lists key companies operating in the global market and also highlights the key changing trends adopted by the companies to maintain their dominance. By using SWOT analysis and Porters five force analysis tools, the strengths, weaknesses, opportunities, and threats of key companies are all mentioned in the report. All leading players in this global market are profiled with details such as product types, business overview, sales, manufacturing base, competitors, applications, and specifications.

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Jude Medical Inc. (U.S.), Starkey Hearing Technologies (U.S.), PerkinElmer Inc. (U.S.), Stryker Corporation (U.S.), Affymetrix Inc. (U.S.) of the major organizations dominating the global market.(*Note: Other Players Can be Added per Request)

1. Industry outlookThis is where youll find the current state of the Nanotechnology in Medical industry overall and where its headed. Relevant industry metrics like size, trends, life cycle, and projected growth included here. This report comes prepared with the data to back up your business idea. On a regional basis, the Global Nanotechnology in Medical market has been segmented into Asia-Pacific, North America, Europe, Latin America, and the Middle East and Africa.

2. Target marketThis target market section of study includes the following:

User persona and characteristics: It includes demographics such as age, income, and location. It lets you know what their interests and buying habits are, as well as explain the best position to meet their needs.

Market size: How big is the potential Nanotechnology in Medical market for your business? It brings to light the consumption in the Nanotechnology in Medical industry by the type and application.

3. Competitive analysisDiscover your competitors. The report lets you know what youre up against, but it also lets you spot the competitions weaknesses. Are there customers that are underserved? What can you offer that similar businesses arent offering? The competitive analysis contains the following components:

Direct competitors: What other companies are offering similar products and services? Which companies are your true competitors?

Competitor strengths and weaknesses: What is your competition good at? Where do they fall behind? Get insights to spot opportunities to excel where others are falling short.

Barriers to entry: What are the potential pitfalls of entering the Nanotechnology in Medical market? Whats the cost of entry? Is it prohibitively high, or easy to enter?

The window of opportunity:Does your entry into the Nanotechnology in Medical industry rely on time-sensitive technology? Do you need to enter early to take advantage of an emerging market?

4. ProjectionsLikewise, We offered thoughtful, not hockey-stick forecasting.

Market share:We have given the consumption behavior of users. When you know how much can your future customers spend, then only youll understand how much of the Nanotechnology in Medical industry you have a chance to grab, and here we came up with real stats and numbers.

Impact Analysis of COVID-19:The complete version of the Report will include the impact of the COVID-19, and anticipated change on the future outlook of the industry, by taking into account the political, economic, social, and technological parameters.

Finally, It is one report that hasnt shied away from taking a critical look at the current status and future outlook for the consumption/sales of these products, by the end users and applications. Not forgetting the market share control and growth rate of the Nanotechnology in Medical Industry, per application. Most noteworthy, this market analysis will help you find market blind spots.

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Nanotechnology in Medical Market Emerging Trends and Capture Significant Growth by 2027 With Worldwide Top Most Players: Jude Medical Inc. (US),...

Global Nanotechnology in Medical Devices Market 2020: Challenges, Drivers, Analysis, Industry Share and Forecast 2025 – Cole of Duty

Global Nanotechnology in Medical Devices Market 2020 by Manufacturers, Type and Application, Forecast to 2025 is generated by MarketsandResearch.biz which provides the analysis of the current status of this business vertical and encompasses a brief synopsis about its segmentation. The report exhibits the records that global Nanotechnology in Medical Devices has set in the past and is expected to set in the forthcoming years from 2020 to 2025. The report focuses on the top players comprising the competitive landscape of the market, as well as the geographical areas where the industry extends its horizons. The report categorizes the market by examining market supply, researching, and demand. The report estimates the market size with respect to valuation as sales volume to provide an accurate prediction of the market scenario over the forecast period.

NOTE: Our analysts monitoring the situation across the globe explains that the market will generate remunerative prospects for producers post COVID-19 crisis. The report aims to provide an additional illustration of the latest scenario, economic slowdown, and COVID-19 impact on the overall industry.

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Industry Coverage:

The report covers competitive developments, such as long-term contracts, new product launches and developments, and research & development activities being carried out by various leading players such as company profiles, product picture, and specification. The report presents a comprehensive overview, market shares, and growth opportunities of global Nanotechnology in Medical Devices market by product type, application, key manufacturers, and key regions and countries. The report also presents the market competition landscape and a corresponding detailed analysis of the major vendors/manufacturers in the market. Detailed market dynamics, industry outlook with market-specific PESTEL, value chain, supply chain, and SWOT Analysis has been served in the report.

The report presents the market competitive landscape and a corresponding detailed analysis of the major vendor/key players in the market. Top companies in the global Nanotechnology in Medical Devices market: 3M, Abbott, Stryker, Dentsply International, Perkinelmer, Mitsui Chemicals, Starkey Hearing Technologies, Affymetrix, AAP Implantate, Smith & Nephew

Geographically, this market report studies the following key geographical regions: North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, etc.), Middle East & Africa (Saudi Arabia, Egypt, Nigeria and South Africa)

The report highlights product types which are as follows: Biochip, Implant Materials, Medical Textiles, Wound Dressing, Cardiac Rhythm Management Devices, Hearing Aid

The report highlights top applications which are as follows: Therapeutic, Diagnostic, Research, etc.

Moreover, this report vastly covers profiles of the companies who have made it big in this particular field along with their sales data and other data. It also suggests the business models, innovations, growth, and every information about the major manufacturers that will be present the future market estimates. The report offers an overall view of the industry with various perspectives along with the several factors which are driving the global Nanotechnology in Medical Devices market report.

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Global Nanotechnology in Medical Devices Market 2020: Challenges, Drivers, Analysis, Industry Share and Forecast 2025 - Cole of Duty

Food Nanotechnology Industry 2020 Includes The Major Application Segments And Size In The Global Market To 2026 – Owned

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Food Nanotechnology Industry 2020 Includes The Major Application Segments And Size In The Global Market To 2026 - Owned

Aerospace Nanotechnology Market 2020 Global Share, Growth, Size, Opportunities, Trends, Regional Overview, Leading Company Analysis And Forecast To…

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Global Aerospace Nanotechnology Market Size & Share, by ProductsNanomaterialsNanotoolsNanodevices

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LaShyra Nolen is pushing for change within Harvard Medical School. Heres what she wants you to know. – Boston.com

In the week after George Floyd was killed in Minneapolis, LaShyra Nolen was asked by her professors each day how she was doing.

To share how she was feeling, the first-year student at Harvard Medical School shared a poem on Twitter, explaining that she could no longer pretend to be okay. In her verses, she drew attention to the disproportionate impacts of the COVID-19 pandemic on communities of color, systemic racism, and police brutality.

The truth is Black students are NOT okay, she wrote.

Nolen, who is the first Black woman to serve as student council president at the institution, is no stranger to advocating for social and racial justice. The Harvard student told Boston.com she believes it is her responsibility to make sure she uses her growing platform in the medical field to fight for health equity and to help tell the stories of communities whose voices are not being heard.

In June, Nolen announced she and her classmates had launched a petition to rename the Holmes Society at Harvard Medical School, named after Oliver Wendell Holmes Sr., citing his promotion of eugenics and violence toward Black and Indigenous peoples.

The same month, the medical student had an essay published in the New England Journal of Medicine that laid out the need for increased representation of Black people and minority populations in medical training, providing examples from her own training.

In one, she noted that her CPR training used mannequins with white male bodies. In another instance, she recalled that during a discussion about Lyme disease in a microbiology class the professor showed photos from the Centers for Disease Control and Prevention of the red bulls-eye rash on white skin, only noting that it is more difficult to see the rash on melanated skin in response to a students question.

If medical students and trainees are taught to recognize symptoms of disease in only white patients and learn to perform lifesaving maneuvers on only male-bodied mannequins, medical educators may be unwittingly contributing to health disparities instead of mitigating them, Nolen wrote.

The California native said she knew since she was in third grade that she wanted to be a doctor, but her dedication and interest in addressing inequities stems from when she moved from Compton to the suburb of Rancho Cucamonga at the age of 10.

It was a completely different life, she said.

The roads were different, the access to basic needs everything was just so plentiful, and that was so different from my experience in Compton and in L.A. she said. That was when I really started to think about differences and race.

She continued to question the disparities she saw between the suburb where she lived, which was predominantly white, and her old neighborhood, which was predominantly Black and Latinx. Those questions took on another layer of urgency when she was 15 and a family member passed away from what she called a preventable death, from complications of obesity and diabetes.

It wasnt until she got to college and learned about the social determinants of health that she began to be able to articulate what shed grown up witnessing, she said.

I started to get a lexicon for all these different things that Id experienced in my childhood, Nolen said. Why we have these differences, how those differences then go on to impact your health, how that impacted my family. All of those things came together, and that is what really inspires my passion because Ive seen it personally. I still continue to see it.

Below, Nolen speaks more about the importance of activism in health care and the changes she hopes to see occur in medical institutions to address systemic racism.

The interview has been lightly edited for clarity and length.

Boston.com: The country is now in a moment of addressing two public health crises COVID-19 and racism. How does it feel to be a medical student right now, and what concerns do you have as efforts to address these two crises move forward?

LaShyra Nolen: Its such an interesting time to be a medical student, and I think its an especially interesting time to be a medical student at Harvard. Because here I am getting this amazing education Im learning about ace-inhibitors, Im learning about the pathophysiology of COVID-19. But even if I get the best education, even if I become the best surgeon, theres still a huge possibility that my patient could walk outside of the clinic and be stopped by a police officer. And if they move too quickly, they might end up losing their life. Or, its very possible that my patient will go back to a community where they dont have access to the basic needs that they need to live out a healthy life.

I think those are the conversations that were starting to finally have. Because it doesnt matter how good medicine gets at finding cures and doing research and pushing the envelope in the biomedical realm, [if] theres still going to be systemic inequity in our society.

If we dont address that, then were never really going to be able to help our patients have the best outcomes that they deserve. As a medical student, Im learning all this science, which is so key for treating your patients. But theres also work that needs to be done outside the clinic it cant stop there.

What were you hoping people would take away from the poem you shared on Twitter, and what was the response that you received after you shared it?

That poem came from a place of all of this turmoil around us being laid to bare. In one context, we have this global pandemic, COVID-19, ravaging through Black communities, Latinx communities, indigenous communities. Then concurrently we have this other pandemic that weve always known to exist systemic racism.

Were seeing so many Black peoples lives being taken on screens, being shown across the country, across the globe. And I was expected to come to class, and I was expected to pretend that everyone was OK. I was expected to just learn the pathophysiology, recite the things that I had studied the night before. That isnt just an experience of medical students its the experience of all Black professionals and all Black students. We have to separate our Blackness from our experience as students and professionals so often. And that was me just saying, Im not OK, and instead of you asking if Im OK, I want you to educate yourself and learn about why Im not OK and make sure that you arent complicit in the system that is contributing to the reason why Im not OK.

Thats really where that came from, and the response that I got from it was really positive. What always surprises me when I speak out is how much feedback Ill get from people who are higher up in the medical hierarchy. Residents and folks who are professors, and they say, Thank you for saying that. Because they dont have the space to say that and be vulnerable and feel comfortable and feel like their jobs arent going to be jeopardy if they say, Hey, Im not doing OK, and, You guys really need to address these issues that were experiencing. It just goes to show how the hierarchy of academic medicine can be harmful.

What do you see as the responsibility you and medical professionals have when it comes to activism? What role do you think doctors or health care professionals should be taking on when it comes to advocacy and social justice, and why do you think its important they are involved?

I think its extremely important. Number one, because I think physicians and health care providers should care about all things that affect their patients health. There have been numerous studies that have come out and shown that access to housing, access to education, access to basic human needs are what folks need to have the best health outcomes. All of that is so inextricably connected to sociology and history and psychology.

We cant continue to just stay in the realm of medicine, because our world gets the benefits from medicine. Almost 20 percent of our GDP comes from health care spending and costs. So we cant just pretend that medicine isnt a political issue, or that its completely separate. Its extremely important for us to not just stay in this lane of medicine because thats just the beginning. When we give the patient the medicine, we have to make sure that theyre able to afford it, we have to make sure that the pill bottle is in the correct language for them to understand, we have to make sure that theyre able to have transportation to get to the clinic. Its so important that we engage in activism because its going to be a huge part of maintaining our patients health and thats essentially what were supposed to be doing as healers.

Given the petition to rename the Holmes Society and your piece in the NEJM, can you speak more to the importance of health professionals addressing institutionalized racism within the institution of medicine and how that can be done?

These are the perfect examples of two buckets that I view advocacy and activism in. One bucket is the inward facing activism. The Holmes Society changing its name is an example of that, because here we have this society where students go to learn, students go to build relationships and form some of their fondest memories of medical school. But the namesake of this institution is someone who was a eugenist, someone who was known to be racist and was actively violent with their words towards indigenous and Black communities. When we have an individual like that representing this space thats supposed to be so wholesome and a safe haven, that can be really dangerous. That work needs to be done so that students of color Black students, indigenous students, Lantinx students can thrive and feel comfortable in these spaces. We cant continue to just recruit students of color and then not protect them when they get to these institutions. Protection goes beyond just evaluations and making sure that they feel like they can thrive academically and arent experiencing micro-aggressions. Its, Who are the people on our walls? How are we allowing violence to be perpetuated silently by who we allow to take up space in these institutions? That is why changing the name of Holmes is so important.

The New England Journal of Medicine piece came out of this idea of more outward facing activism. Even though its a change that needs to happen within the medical institution, if were graduating physicians who dont even know how to recognize key symptoms in patients of color or if we dont graduate physicians who understand the nuance of doing CPR on a person with breasts the fact that you have to take off that persons shirt and how uncomfortable that might be for that individual and talking about issues of consent its just so much more nuanced to the different things were learning. But we just ignore it. They call it the reference man we always use men as the reference, particularly white men. Thats so problematic because that can go on to perpetuate health disparities in the communities that we seek to serve.

If were going to be institutions that are mission-driven and we want to increase diversity within our medical school and we want to help mitigate health disparities, we have to look at the small insidious ways that we might be actually doing more harm than good. The worst part is that often Black students, the marginalized student, is often the person that has to put themselves out there to ask that question. And I think that in itself is a really big issue because why is that my non-Black peers didnt raise their hands and say, Hey, how would I recognize this in a patient with darker skin? Because those are going to be their patients, too. Thats the direction we have to move in this antiracist movement it shouldnt be that its always the responsibility of the marginalized person to stand up for the marginalized group. It should be a collective effort that we all value the humanity of all patients. And I really hope thats the direction that we go in.

In a speech last August, you addressed young Black girls, saying You cant be what you cant see when it comes to diversity in medicine. Can you speak to more of what you meant when you said that medicine will not progress without the diversity of having young Black women going into the field, and what changes do you want to see taken to ensure theres greater diversity?

I think it will play a very important role in the future. I personally did not see a Black doctor until the summer of my freshman year of college. I had gone through my entire life with this dream of becoming a doctor, and the reason why that dream was kept alive is because I had a grandmother and a mother who believed in me endlessly, even though they had never necessarily seen a Black doctor before. They just believed in me and they just breathed life into my dreams, but it wasnt until I saw that Black doctor that it all clicked, and I said, OK, it seems like its possible to actually achieve this dream. We have to start exposing youth to the sciences early on, and beyond just exposing youth to the sciences, we also have to mitigate the different forms of structural racism that are embedded in society. We have to think about, How is that when I build a new building for my medical school, that Im then taking tax revenue away from the city? And then, How is that going to affect how schools are able to invest in educational programs? We have to think about how we as institutions are complicit in systemic racism beyond just having these pipeline programs. We have to have a two-fold approach to addressing this issue of representation, but then also making sure that were doing the work to mitigate systemic racism.

Is there anything else you want to say or want people to know?

Antiracism has to be an every day, every moment work. It cant be something that only lasts this summer, it cant be something that only lasts in 2020. It has to be something that people are actively engaging in every moment of their life, because racism is so deeply embedded into the fabric of America and into the fabric of our everyday lives that we dont even realize it. Therere many different ways people can mitigate this, but its going to happen through uncomfortable conversations, speaking out against the ways that systemic racism has silently been able to fester in our academic environments, among other things. This work is uncomfortable and its ongoing, and we should never stop.

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LaShyra Nolen is pushing for change within Harvard Medical School. Heres what she wants you to know. - Boston.com

What Challenges Affect the Cost of Running a Cryptocurrency Exchange – Cointelegraph

Running a cryptocurrency exchange comes with a lot of considerations. What are the regulations in the country you operate in? Do you have sufficient liquidity? How will you handle security? Adhering to all of these requirements leads to excessive costs involved with setting up and operating these platforms, which means that a high price is often required to get a coin listed on them. This only makes it that much harder for new assets to find a market.

Depending on where you are in the world, the regulations concerning cryptocurrency can be anywhere from strict to completely absent, with changes often coming swiftly after long periods of silence. While local rules can vary greatly, many governments have been moving toward stronger Anti-Money Laundering laws, such as the European Unions 5th Anti-Money Laundering Directive, which is currently forcing some firms in the EU to rethink their location.

In the United States, Representative Paul Gosar, a Republican from Arizona, introduced the Crypto-Currency Act of 2020, which would see unique definitions and oversight of crypto commodities, cryptocurrencies and crypto securities. Moreover, South Korea just passed a law requiring cryptocurrency exchanges to partner with banks to enforce AML policies. Meanwhile, the Reserve Bank of India recently lifted a ban on cryptocurrency that had only been enacted in April of 2018.

The point here is that regulations are subject to change based on geopolitical location and can also quickly evolve within just one jurisdiction. This can be costly to mitigate for exchanges. Paying for professional help just to understand the latest laws can add up, as can employing the teams necessary to collect and verify AML documentation from customers. However, failing to do so could lead to expensive fines or even to the platform being shut down. Unfortunately, these regulations are rarely seen as optional once they are decided upon.

Regulations arent the only obstacles for new exchanges. Issues can arise just in the act of setting up an exchange. There are myriad facets to think about, and all of them can be complex and expensive. Designing an interface, programming the matching engine, integrating AML practices, and working with local banks are just a handful of the concerns a team setting up a new exchange would need to address. All of these would also need a fair amount of time just to be implemented. Then, there is interacting with multiple blockchains in real time, security systems, and the sheer cost of storing and maintaining servers. The amount of time needed just to find quality programmers, build the codebase and debug it can easily take a year or longer if a team is starting from scratch.

Even once that has all been navigated, and the exchange is live, there will still be ongoing and expensive issues to contend with. Take liquidity, for example, which can be a major problem for smaller exchanges as well as smaller markets. This refers to the small number of buyers and sellers available to give traders confidence that they can make the trades they want when they want. Without this, traders will often miss out on opportunities because they cannot enter or exit a position in time, which will be frustrating and hurt business.

In other words, exchanges want to bring in as much traffic as possible and to curate a user experience that pleases everyone. Here, things like security and customer service are front and center. Clients want to know that the exchange is safe from both outside hackers and inside operators and that funds are always available where the exchange says they will be. Inevitably, there will be some mistakes or technical issues. This is why it is important to have support teams to address upset customers, as well as others to fix issues with the platform. Having the capability to respond to all of these matters doesnt come cheap, but without this, a new platform will surely fail.

In addition to the aforementioned issues, it can take a significant amount of capital to open and operate a cryptocurrency exchange. This can lead to platforms having large fees attached to listing fresh assets, which harms new development teams. It also causes much of the market to be channeled through a handful of gatekeepers, namely, the biggest exchanges that have already established themselves.

This is clearly problematic for smaller projects that arent already available across multiple exchanges. If they cannot raise the capital needed to be listed on larger platforms, which can often be in the $100,000 range or higher, then nobody would be able to buy them. Of course, in that case, they wont grow, and potentially sound ideas may get wiped out due to lack of liquidity and exposure. Projects need a way to know that they can create their own market when necessary, but for the most part, the costs may be too steep to launch an exchange platform.

This is where white-label exchanges enter the picture. A white-label exchange uses specially designed software to launch a new platform fast and cheap. A team, for example, could get an exchange running in days instead of months, and for thousands of dollars as opposed to millions. These exchanges generally follow templates but are highly customizable and can negate the need for a company to develop its own proprietary software. Generally, the software should provide everything necessary to get up and running, as well as to be in compliance, though not all exchanges are identical. It is important to know about a few specific options that are available.

In general, exchanges can be centralized or decentralized, and cloud-based or do-it-yourself. A centralized exchange means you will be hosted on another companys servers, which are generally paired with cloud-based models. It could also be hosted on your own servers, but this will also be cost-prohibitive for most. While you wont have as much control, usually the company offering this will handle a great deal of the operations behind the scenes, as well as manage technical issues. Although they offset some costs, subscription fees help to keep the platform running, but the upfront costs of getting started should be relatively cheaper.

DIY exchanges can be either centralized or decentralized, but when it is decentralized, it runs across many servers, and not simply by a single third-party entity. The DIY part means that while the software may be set up to assist you, there will generally not be anyone else operating the exchange behind the scenes. These packages may also come with subscriptions that allow you to access a team of experts for support, but you will be making the final decisions. Such offerings may be less expensive on a monthly basis but can often still have larger, one-time fees associated with being allowed to run the software.

One solution that solves many of the issues faced by teams looking to create new exchanges is the HollaEx Kit, offered by bitHolla. The kit is open-source, free to install and offers the most comprehensive set of tools for anyone to create a new cryptocurrency exchange in minutes. It includes a desktop and mobile user interface, a trade matching engine, and an administrative control panel. You can add any trading pairs you choose, including your own newly created coins or tokens. It is also designed to keep you in compliance with most modern regulations by offering a system that collects relevant AML data from your customers.

The process of setting up a new platform is streamlined, and there are options for getting advanced help from bitHollas team of experts. This makes HollaEx Kit the most attractive option for development teams who need to create new markets for their coins but cant afford to pay the exorbitant fees that come with most exchanges. The bitHolla team has created a product that seeks to be the WordPress of building exchanges. In time, DIY software will likely become the gold standard and will be increasingly integrated into more websites, potentially weakening the draw of centralized services. This is what bitHollas HollaEx Kit is trying to achieve with this software package, which will hopefully make access to building the cryptocurrency market a bit easier for everyone.

Disclaimer. Cointelegraph does not endorse any content or product on this page. While we aim at providing you all important information that we could obtain, readers should do their own research before taking any actions related to the company and carry full responsibility for their decisions, nor this article can be considered as an investment advice.

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What Challenges Affect the Cost of Running a Cryptocurrency Exchange - Cointelegraph

Huobi Global Provides Insight on What Is Driving the Institutional Interest in Cryptocurrency Investment – PRNewswire

LONDON, July 10, 2020 /PRNewswire/ -- Huobi,has seen aninflux of traditional and institutional traders join their platform and take advantage of the Huobi Futures market place. As of May 6, Futures and Swap Trading Volume at Huobi topped $5.2 billion, with 24 hour perpetual swap trading volume hitting $2.2 billion this is off a product that was only launched in April.

What is most interesting to see is that the Institution trading percentage on Huobi futures is estimated to as high as 30 to 40 percent.

This year has been a defining one for a number of reasons. The world has faced a global pandemic, and the traditional markets and economies around the planet have had to try and deal with this unprecedented event. It has also been a year that looks set for greater interest in cryptocurrency investment.

Internally, the cryptocurrency space has been on the rise in the mainstream as regulations, governments, and traditional institutions have come to normalize and legitimize much of the space. But now, externally, there is financial uncertainty in the traditional space and many retail and institutional investors are casting their eyes to new avenues.

Peoplehave seen Paul Tudor Jonespraise Bitcoinfor its potential as a speculative asset, stating he invests a small percentage of his portfolio in the coin, but expects it to be the best performer. People have also seen Grayscale Bitcoin Trustbuying up a major portion of coins newly mined after the Bitcoin halving.

But, what is it that is drawing institutional interest into the cryptocurrency market other than the current internal and external factors surrounding it. Huobi spoke with Ciara Sun, VP of Huobi Global Markets, to find out more.

What makes the market grow?

"The price volatility and high liquidity of digital assets are especially attractive to investors," explained Ciara Sun. "The crypto market is unique in that it can fulfil both demands in liquidity and volatility.

"For example, traditional investments like real estate have price volatilities but lack of liquidity. Foreign exchange markets have high liquidity but lack price volatility. Investors see arbitrage opportunities in crypto as an emerging market. An above averagerange annual return can be seen as good performance in the traditional market, but is actually a quite mediocre return in the crypto derivative market."

Clearly, the crypto market is an exciting place to be for investors. It is renowned for its high volatility, but this is a double-edged sword. For people who know how to trade well, and be safe, volatility is indicative of opportunity.

But, there is also the opportunity to use crypto to be safe and to avoid risky situations.

"Additionally, digital assets can offer investors a way to hedge risk against government intervention. Traditional assets are directly influenced by monetary policies and economic measures like quantitative easing, but digital assets are decoupled from the acts of any one nation or governing body. At a time when governments around the world are printing currency to stabilize their economies, digital assets can be one way to hedge against inflation," Ciara Sun added.

"On Huobi, we have seen a 3-4X growth in institutional trading on derivative markets since early last year. Institutional clients now account for 40% of our trading volume. Our growth in Russia is especially pleasing."

"Generally speaking, whether for institutional or individual traders, they want to choose a trading platform with good liquidity and market capitalization. Huobi manages 5% of crypto assets in the market and we are ranked the number 1 in liquidity by Coinmarketcap.

A reliable platform

Part of the growth in interest in the cryptocurrency space from institutional investors is also part of the growth of cryptocurrency providers. The expansion of CME and Bakkt is one side of it, but many institutions are coming to places like Huobi because of the professional platform provided.

Contact: Hailan - [emailprotected]

SOURCE Huobi Global

http://huobi.com

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Huobi Global Provides Insight on What Is Driving the Institutional Interest in Cryptocurrency Investment - PRNewswire

Kaspersky Fraud Prevention helps Indacoin halt fraudulent operations with cryptocurrency – CRN.in

One of cryptocurrencys main benefits is the ability to conduct trusted transactions swiftly. However, the anonymous and decentralized nature of these transfers can be leveraged by fraudsters to wash money or trick legitimate crypto investors. In order to keep their customers investments truly clean, exchange service Indacoin has adopted Kaspersky Fraud Prevent to halt this foul practice.

Many fraudsters launder funds from stolen cards or using leaked card details before they transfer them to their bank accounts and it is estimated that around three-quarters of laundered cryptocurrency in 2018 was washed with an exchange service. They are also able to manipulate crypto exchange users to transfer money into another account by impersonating security service members and using tools for remote access. As this software is legitimate, traditional security solutions may not be alerted to any risks and mark it as dangers. These cases not only put users investments at risk but also negatively impacts the reputation of exchange services.

It is critical to identify and block these damaging transactions, without affecting the speed of legitimate transfers of funds. The cryptocurrency exchange rate is known to be quite erratic. which means investors rely on their payments being processed very quickly.

Indacoin, a leading fiat-to-crypto exchange, provides a simplified verification process, which allows customers to use its partners services without any additional difficulties. To eliminate risks of the platform being misused, Indacoin has turned to the Kaspersky Fraud Prevention service. The Automated Fraud Analysis uncovers fraudulent transactions in real-time. It also can detect fraudster groups through global device reputation and extended fingerprinting analysis, so it is capable of detecting suspicious activity before the act of fraud has actually damaged the business.

As a result of Kaspersky Fraud Prevention being integrated into Indacoins antifraud system, its efficiencies rose by 38%. The most noticeable improvement was the ability to identify operations when operations were conducted on a clients computer or phone via remote access.

Anvar Sidorov, Director of Partnerships at Indacoin, provided his commentary: The crypto exchange has many unique features, but in general, we share the main risks of financial institutions: security of cards and payment information, as well as security of personal accounts and safety of clients funds. The implementation of Kaspersky Fraud Prevention helped to identify highly targeted fraud schemes, identify dishonest users with advanced precision and implement machine learning in the verification system.

We are delighted to be chosen by Indacoin, and it is always great to see a business take cybersecurity seriously. Fraudulent transactions are common on crypto exchange services and this has the potential to damage investor loyalty in this new sphere. By integrating Kaspersky Fraud Prevention with their exchange, Indacoin is positioning itself as a trusted partner for cryptocurrency investors in what is a highly competitive market, comments Claire Hatcher, Head of Business for Kaspersky Fraud Prevention.

If you have an interesting article / experience / case study to share, please get in touch with us at editors@expresscomputeronline.com

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Kaspersky Fraud Prevention helps Indacoin halt fraudulent operations with cryptocurrency - CRN.in

And When He Came to Himself (Luke 15:17)

The following address was given June 17, 2020, for the digital-only 2020 BYU Law School Religious Freedom Annual Review. Read a summary article of the speech.

I am grateful to participate with you in the Religious Freedom Annual Review at the J. Reuben Clark School of Law at Brigham Young University. This is a most opportune time to consider together the importance of religious freedom. And I appreciate the invitation to share a few of my thoughts with you.

In the 15th chapter of Luke in the New Testament, we learn about a young man who obtained his inheritance from his father and then traveled to a far country.[i] This young man wasted his substance with riotous living.[ii] When he had squandered all of his resources, a mighty famine arose in that land, and he began to be in want.[iii]

And he went and joined himself to a citizen of that country; and he sent him into his fields to feed swine.

And he would fain have filled his belly with the husks that the swine did eat: and no man gave unto him.

And when he came to himself, he said, How many hired servants of my fathers have bread enough and to spare, and I perish with hunger!

I will arise and go to my father, and will say unto him, Father, I have sinned against heaven, and before thee,

And am no more worthy to be called thy son: make me as one of thy hired servants.

This story has a marvelously happy ending. The return of this son to his home led to a loving reconciliation with his father and a restoration of his station in his family.

The parable of the prodigal son describes the experience of a young man who became lost and subsequently found his way back home. Please note two key aspects of this young mans experience.

First, he began to be in want when a mighty famine arose in the land. As this natural calamity unleashed its negative effects, I presume his inheritance was gone. I also imagine that many of the friends who enjoyed his companionship while he had plenty of money had long since told him goodbye. He may have been homeless. But ultimately, it was the famine and his resultant hunger that constituted a strong wake-up call. He was shaken awake from the customary patterns of his lifestyle by an increasing realization of his inability to fulfill his most basic needs.

Second, the young mans wake-up call led him to come to himself. This poignant phrase suggests to me a process of examining aspects of his life that previously had been unexamined, resulting in a piercing personal realization of his present circumstances and what he had become. He also was willing to strive for a timely and needed course correction: I will arise and go to my father.

Our world has seemingly been filled recently with strong wake-up calls. From natural disasters to a deadly pandemic sweeping the globe to a most pernicious social plague of racism, we are daily reminded that we need to awaken to the perilous times that surround us, come to ourselves, and arise and turn to our Divine Father, who desires to instruct and edify us through our trials.

Just as the famine for the prodigal son was a pivotal turning point in his life, so COVID-19 can help us to realize what we have not fully realized before. The following video highlights a number of simple wake-up calls that people have received because of COVID-19.

Several years ago, I spent a Sunday afternoon in the home of my apostolic associate, Elder Robert D. Hales, as he was recovering from a serious illness. We discussed our families, our quorum responsibilities, and important life experiences.

At one point I asked Elder Hales, You have been a successful husband, father, athlete, pilot, business executive, and Church leader. What lessons have you learned as you have grown older and been constrained by decreased physical capacity?

Elder Hales paused for a moment and responded, When you cannot do what you have always done, then you only do what matters most.

I was struck by the simplicity and comprehensiveness of his answer. My beloved friend shared with me a lesson of a lifetimea lesson learned through the crucible of physical suffering and spiritual searching.

For Elder Hales, the limitations that were the natural consequence of advancing age, in fact, had become remarkable sources of spiritual learning and insight. The very factors that may have appeared to limit his effectiveness became some of his greatest strengths. Physical restrictions expanded his vision. Limited stamina clarified his priorities. Inability to do many things directed his focus to a few things of greatest importance.

Thus, constraints and limitations can be remarkable blessings, if we have eyes to see and ears to hear. And this same truth applies to all of us today as we wrestle with the effects of a pandemic.

COVID-19 Wake-Up Calls

The following examples highlight some of the things we may now see and hear more distinctly because of the demands and constraints imposed upon us by COVID-19.

COVID-19 has alerted us to many of the limitations in the supply chain processes that bring food from the fields, farms, and processing plants to our local grocery stores and kitchen tables.

COVID-19 has alerted us to our dependence upon foreign nations for many of our essential medical supplies, pharmaceuticals, and a wide variety of other strategically important products.

COVID-19 has alerted us to many of the constraints of just-in-time inventory and delivery systems for manufacturing plants and retail businesses.

COVID-19 has alerted us to many of the deficiencies in our national and local health care systems.

COVID-19 has alerted us to the importance of defending the borders between personal liberty, constitutional rights, and governmental authority.

COVID-19 has alerted us to many attacks on the freedoms of religion, speech, and assembly.

And the list goes on. The buzzer on the COVID-19 alarm clock just continues to ring and ring and ring.

COVID-19 and Religious Freedom

The Annual Review is a time to reflect on religious freedom and its place in the law, the nation, and our personal lives. Doing so in the midst of COVID-19 sharpens our focus. This present crisis may well be a moment when we too come to ourselves and realize, perhaps as never before, just how precious and fragile religious freedom is.

Religious Freedom and the Right to Gather with the Faithful

One key realization is that for most faith communities, gathering for worship, ritual, and fellowship is essential; it is not merely an enjoyable social activity.

For example, gathering is an especially powerful element in the doctrine of The Church of Jesus Christ of Latter-day Saints. A central mission of the Church is to gather together the scattered family of Abrahamand indeed all who are willingto the ordinances and covenants of the Saviors gospel. Through that gathering, we believe God will establish a people who are of one heart and one mind, who dwell together in righteousness and peace, and who love and care for each other so completely that no poor, spiritually or physically, are found among them.[v]

In ancient and modern scripture, the Lord calls such a people and such a place Zion. Zion is where the pure in heart[vi] dwell. And it is where God Himself can dwell in the midst of His people.[vii] We believe that such a gathering is essential before the Messiah returns again.[viii]

This vision of gathering has been a driving motivation for the Latter-day Saints since the Churchs earliest days and inspired our members to assemble first in Ohio and then in Missouri and Illinois. At each stage, government and mobs combined to persecute and scatter our members until they eventually found a place of gathering outside the United Statesin what later became the state of Utah.

This vision has inspired our building of holy temples, where through sacred ordinances and covenants we eternally gather our families to God.

And this vision continues to inspire Latter-day Saints to gather together in their local congregations to worship God and His Son Jesus Christ, partake of the Sacrament of the Lords Supper, and strengthen, serve, and fellowship each other.[ix]

Being in each others presence is a unique and irreplaceable experience. In Christianity, the God of the Old Testament came to His people in the flesh. Jesus Christ touched people, embraced them, healed them, ministered to them. And we believe we are called to do as He did.[x] He taught, Where two or three are gathered together in my name, there am I in the midst of them.[xi]

Of course, Latter-day Saints are hardly alone in this need to gather as a religious community. Our Catholic, Orthodox, Protestant, and Evangelical friends gather for mass, baptisms, confirmations, sermons, and myriad other religious purposes.

Our Jewish friends gather for worship in their synagogues.

Our Muslim friends gather in their mosques.

Our friends in the Buddhist, Sikh, and other faith traditions likewise have sacred places to gather and worship together.

Gathering, in short, is at the core of faith and religion. Indeed, if the faithful are not gathering, sooner or later they will begin to scatter.

And because gathering lies at the very heart of religion, the right to gather lies at the very heart of religious freedom.

COVID-19 and Unprecedented Restrictions on Religious Exercise

I believe it is vital for us to recognize that the sweeping governmental restrictions that were placed on religious gatherings at the outset of the COVID-19 crisis truly were extraordinary. In what seemed like an instant, most Western governments and many others simply banned communal worship. These restrictions eliminated public celebrations of Easter, Passover, Ramadan, and other holy days around the world.

No other event in our lifetimeand perhaps no other event since the founding of this nationhas caused quite this kind of widespread disruption of religious gatherings and worship.

The COVID-19 restrictions affected The Church of Jesus Christ of Latter-day Saints in a unique way. The Churchs April 2020 General Conferencea celebration of the bicentennial of the First Vision of the Prophet Joseph Smithhad to be broadcast to a global audience from a small auditorium with only a handful of people attending instead of from our large conference center with a congregation of more than 20,000 people.

Clearly, governments have an affirmative duty to protect public health and safety.[xii] And I believe public officials have most often sought to do the right things to protect the public from the virus. Drawing proper lines to protect both public health and religious exercise in a pandemic is very challenging.

But we cannot deny and we should not forget the speed and intensity with which government power was used to shut down fundamental aspects of religious exercise. These decisions and regulations were unprecedented. For nearly two months, Americans and many others throughout the free world learned firsthand what it means for government to directly prohibit the free exercise of religion.

Reflections on the Nature of Government and the Importance and Fragility of Religious Freedom

Like the prodigal son who came to himself in the midst of crisis, our own time of being in want invites us to carefully reflect on fundamental principles that perhaps we have long taken for granted. Here are a few of my own reflections.

First reflection: Government power can never be unlimited. In our political system, the government derives its just powers from the consent of the governed, to quote the Declaration of Independence. But the just powers of government cannot be unlimited, because they exist most fundamentally to secure the God-given rights of life and liberty, so that each of us can exercise our moral agencythe ability to act for [ourselves] and not to be acted upon[xiii]and be accountable before God for our choices and actions.

Constitutions, representative government, checks and balances, and the rule of law help constrain the tendency of government to exercise unlimited power. Of course, liberty has limits. Government has a just role in fostering a moral environment in which people can live good and honorable lives. But whatever else government officials may be called upon to do, we the people must never allow them to forget that their offices and powers exist to secure our fundamental freedoms and the conditions for exercising those freedoms.

Thus, despite the obvious need for a proper response to COVID-19, we must not become accustomed to sweeping assertions of governmental power. Invoking emergency powers, government executives summarily imposed numerous orders and directives that in many ways are analogous to martial law. These executive orders are unlike laws enacted through the ordinary give-and-take of the democratic process.

No doubt an emergency on the scale of COVID-19 justifies strong measures to protect the public, but we cannot lose sight of the fact that many of these measures are extraordinary assertions of governmental power that can dramatically constrain our basic freedoms. The power of government must have limits.

Second reflection: Religious freedom is paramount among our fundamental rights. This time of restriction and confinement has confirmed for me that no freedom is more important than religious freedom. The freedom of religion properly has been called our first freedom. It is first not only because of its placement as the first right in the First Amendment, but also because of the paramount importance of respecting the moral agency of each person. Living even for a brief few weeks under the restrictions imposed on religious activity by COVID-19 is a stark reminder that nothing is more precious to people of faith than the freedom to worship Almighty God according to the dictates of our own conscience[xiv] and to openly and freely live according to our convictions.

Religious liberty is one of the just and holy principles[xv] underlying the Constitution of the United States. That liberty draws from and in turn reinforces the other rights protected by the First Amendmentthe right to speak freely, to make use of a free press, to peaceably gather with others, and to petition the government to redress grievances.

Freedom of religion stands as a bulwark against unlimited government power. It safeguards the right to think for oneself, to believe what one feels to be true, and to exercise moral agency accordingly. It secures the space necessary to live with faith, integrity, and devotion. It nurtures strong families. It protects communities of faith and the rich and sacred relationships they make possible.

Nothing government does is more important than fostering the conditions wherein religion can flourish.

Third reflection: Religious freedom is fragile. As we have just experienced, religious freedom can quickly be swept aside in the name of protecting other societal interests. Despite COVID-19 risks, North American jurisdictions declared as essential numerous services related to alcohol, animals, marijuana, and other concerns. But often religious organizations and their services were simply deemed nonessential, even when their activities could be conducted safely. In the name of protecting physical health and security or advancing other social values, government often acted without regard to the importance of protecting spiritual health and security. It often seemed to forget that securing religious freedom is as vital as physical health.

Fourth reflection: In a time of crisis, sensitive tools are necessary to balance the demands of religious liberty with the just interests of society. I am not for a moment saying that religious freedom can be unlimited in the middle of a pandemic. Nor am I saying that all government officials have disregarded religious rights. Far from it.

What I am saying is that we can no more disregard the valid claims of religious freedom in a time of crisis than we can disregard the valid claims of freedom of speech, freedom of the press, or freedom from unreasonable searches and seizures. Nor should we prioritize secular interests above religious ones. A health crisis should not become an excuse for a religious freedom crisis.

I believe we must always remember a key principle: specifically, religion should not be treated less favorably than analogous secular activities.

For example, the orders of one state barred Catholic priests from anointing a parishioner with holy oil in the performance of last riteseven if the person was not sick with COVID-19, even if the priest and parishioner were protected with masks and gloves, and even if the oil was applied with a swab. In the same state, my Church could not perform baptisms even under the safest of conditions.

Protecting a persons physical health from the coronavirus is, of course, important, but so is a persons spiritual health. That same state allowed lawyers to meet with people to administer to their legal needs, allowed doctors to meet with people to administer to their health needs, and allowed caregivers to administer food to satisfy nutritional needs. But it did not allow a clergyperson to administer to a persons religious needs, even when the risk of all these activities was essentially the same.

This example and many more like it illustrate a profound devaluing of religion. We can and must do better.

I also believe we must always remember a second essential principle: namely, policy makers, even in a crisis, should limit the exercise of religion only when it truly is necessary to preserve public health and safety.

When the needs of society are great, officials should still ask whether there is some way of addressing those needs other than by burdening or banning the exercise of religion. With goodwill and a little creativity, ways can almost always be found to fulfill both societys needs and the imperative to protect religious freedom.

After all, the COVID-19 virus is not attracted uniquely to religious people. As most of us now recognize, a variety of methods can be used to mitigate the risk of the virus that do not require outright prohibitions on religious worship or gatherings.

The Opportunity Before Us

The COVID-19 crisis has presented us with a unique opportunity to reaffirm and shore up religious freedom. We have witnessed the governments swift, well-intentioned, but often dangerous breaching of the boundaries that protect the free exercise of religion. Do we hear the buzzer on the alarm clock? This is a wake-up call for all of us. Those fundamental boundaries and protections must be healed, renewed, and fortified.

While believers and their religious organizations must be good citizens in a time of crisis, never again can we allow government officials to treat the exercise of religion as simply nonessential. Never again must the fundamental right to worship God be trivialized below the ability to buy gasoline.

Conclusion

In the midst of crisis, the prodigal son in the biblical parable came to himself and began the long journey back to his home. No doubt in that moment he realized the error of his ways. But more fundamentally, I think he also realized that he had forgotten who he was. There, among the swine, he remembered. And then everything changed.

In our understandable desire to combat COVID-19, we, too, as a society may have forgotten something about who we are and what is most precious. Perhaps we have not fully remembered that faith and the right to exercise it are central to our identity as believers and to all that we deem good and right and worthy of protection. Now is the time for us to heed the wake-up call, to remember, and to act. That we may do so is my hope and my earnest prayer.

As I now come to the end of my message, I joyfully exercise what for me, personally, is one of the greatest religious liberties. I express these thoughts in the name of Him whom I serve, whom I love, and whom I represent, even Jesus Christ, amen.

[iv] Luke 15:14-20; emphasis added.

[v] See Moses 7:18; Mosiah 18:2122.

[vii] See Moses 7:69; Matthew 5:8.

[viii] See Russell M. Nelson, The Future of the Church: Preparing the World for the Saviors Second Coming, Ensign, April 2020, 1317.

[xiv] Articles of Faith 1:11.

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And When He Came to Himself (Luke 15:17)

MINISTER’S MOMENT / By REV. WILL WILSON | A Christian perspective on freedom – Kilgore News Herald

Modern understandings of freedom are grounded in the idea of the absolute autonomy of the individual.

We moderns believe that freedom is the ability to do whatever we want, whenever we want it, and however we want without any constraints. This definition sounds attractive, but if it is true then inevitably my freedom will eventually impinge on someone elses freedom.

For example, someones absolute freedom to smoke could rob another persons freedom to breath clean air. Another example: my freedom to choose to play loud music on my stereo could potentially rob someone elses freedom to live in peace and quiet.

By now you get the point: true freedom cannot be defined as the ability to do whatever one wants, when they want it, because one persons freedom could be another persons limitation.

What, then, is a better account of freedom? From a Christian perspective, true freedom is the ability not to do whatever we want, but what God wants. When the children of Israel were enslaved in Egypt, the only choice they were given was to serve the Pharaoh and do his bidding. Pharaoh determined all aspects of Israels lifewhen they worked, when (or if) they rested, and whom they worshiped.

The Israelites were slaves in Egypt. Yet, upon their deliverance from bondage, their freedom from Pharaoh meant that they were now free for the service and worship of God. The ten commandments were given as laws through which Israel could live into this newly received freedom.

Ive heard a lot about freedom lately as it relates to the recent government mandated facemasks. Many people refuse to wear them because they feel that the directive is a threat to their right to choose to dress how they want. Some feel that it should not be the responsibility of government to tell its citizens what they can or cannot wear.

In my opinion, such sensibilities reveal an unbiblical understanding of what being free actually means. Its not to do whatever one pleases, but rather it is the opportunity to do what is morally right by God and by neighbor.

Through Christs atoning death on the cross and Gods raising him from the dead, we Christians are now free from sin and free for loving God and each other. So, exercise your freedom and put on a mask.

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MINISTER'S MOMENT / By REV. WILL WILSON | A Christian perspective on freedom - Kilgore News Herald

The impact of the health crisis on freedom of expression and media freedom – Report by the Secretary General of the Council of Europe, Marija Pejinovi…

Over a year ago, the declaration adopted by the Committee of Ministers in Helsinki on the occasion of the 70th anniversary of the Council of Europe stressed that "free and pluralist public debate is an essential condition for democracy and we must take firm action to reverse the recent deterioration of freedom of expression in Europe". The work of the Council of Europe, including the activity of the Platform for Strengthening the Protection of Journalism and the Safety of Journalists, indicates that this trend has not been reversed, far from it. This challenge calls for co-ordinated action in various areas affecting freedom of expression.

The report published by the Secretary General aims to highlight areas where freedom of expression may be put under stress in the present circumstances, and to recall the applicable standards and the means available to member States and the Council of Europe to meet the challenges they face.

Media in times of health crises

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The impact of the health crisis on freedom of expression and media freedom - Report by the Secretary General of the Council of Europe, Marija Pejinovi...

Litecoin (LTC) Up $0.05 On 4 Hour Chart, Came Into Today Down For the 2nd Day In A Row; Price Base in Formation Over Past 90 Days – CFDTrading

Litecoin 4 Hour Price Update

Updated July 11, 2020 07:22 AM GMT (03:22 AM EST)

Litecoin closed the previous 4 hours up 0.11% ($0.05); this denotes the 3rd candle in a row an increase has occurred. Relative to other instruments in the Top Cryptos asset class, Litecoin ranked 3rd since the previous 4 hours in terms of percentage price change.

Litecoin is down 0.18% ($0.08) since yesterday, marking the 2nd day in a row it has gone down. The change in price came along side change in volume that was down 36.48% from previous day, but up 64.94% from the Friday of last week. Out of the 5 instruments in the Top Cryptos asset class, Litecoin ended up ranking 3rd for the day in terms of price change relative to yesterday. The daily price chart of Litecoin below illustrates.

The first thing we should note is that the current price of Litecoin is sitting close to its 20, 50 and 100 day moving averages; moving average crosses often indicate a change in momentum, so this may be worth keeping an eye on. Trend traders will want to observe that the strongest trend appears on the 14 day horizon; over that time period, price has been moving up. Also of note is that on a 90 day basis price appears to be forming a base which could the stage for it being a support/resistance level going forward. For additional context, note that price has gone up 7 out of the past 14 days. Also, candlestick traders! Note we see pin bar pattern appearing here as well.

For laughs, fights, or genuinely useful information, lets see what the most popular tweets pertaining to Litecoin for the past day were:

@Cardano_Guy @CryptoIRELAND1 @litecoin @IOHK_Charles @_Cardano_ADA @HukAleksandra @TheCryptoLark Completely agree. Co-operation is what is required in the eco-system. Lets get rid of these squabbles and start to build the future; as long as were part of the ecosystem; after all, thats why this is blockchain 3.0

This cryptocurrency, Dogecoin: shit started as a joke back in 2013, right?actually a pretty solid crypto with a silly name attached to it running on a similar code as Litecoin without a cap so its very volatile/reliable & low exchange fees

It seems like the spirit of the Cypherpunk Manifesto is in favor of experimentation and sharing of code to make a better world so forks & alts fit that.Again very different story if there was a fundraise that changes things a lot Im talking Litecoin, Monero etc.

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Litecoin (LTC) Up $0.05 On 4 Hour Chart, Came Into Today Down For the 2nd Day In A Row; Price Base in Formation Over Past 90 Days - CFDTrading

Litecoin (LTC) Up $0.1 Over Past 4 Hours, Entered Today Down 0.18%; Price Base in Formation Over Past 90 Days – CFDTrading

Litecoin 4 Hour Price Update

Updated July 11, 2020 01:36 AM GMT (09:36 PM EST)

44.25 (USD) was the opening price of the four-hour candle for Litecoin, resulting in the last 4 hour candle being one in which price moved up 0.23% ($0.1) from the last 4 hour candle. Relative to other instruments in the Top Cryptos asset class, Litecoin ranked 2nd since the last 4 hour candle in terms of percentage price change.

Litecoin closed the day prior down 0.18% ($0.08); this denotes the 2nd day in a row it has gone down. The change in price came along side change in volume that was down 36.48% from previous day, but up 64.94% from the Friday of last week. Out of the 5 instruments in the Top Cryptos asset class, Litecoin ended up ranking 3rd for the day in terms of price change relative to the day prior. Here is a daily price chart of Litecoin.

The first thing we should note is that Litecoin is now close to its 20, 50 and 100 day moving averages, which may act as price barrier for the asset. Trend traders will want to observe that the strongest trend appears on the 14 day horizon; over that time period, price has been moving up. Price action traders in particular will want to note that the 90 day period appears to show price forming a base; this could indicate that a support/resistance level is developing. For another vantage point, consider that Litecoins price has gone down 16 of the previous 30 trading days. Also, candlestick traders! Note we see pin bar pattern appearing here as well.

For laughs, fights, or genuinely useful information, lets see what the most popular tweets pertaining to Litecoin for the past day were:

@Cardano_Guy @CryptoIRELAND1 @litecoin @IOHK_Charles @_Cardano_ADA @HukAleksandra @TheCryptoLark Completely agree. Co-operation is what is required in the eco-system. Lets get rid of these squabbles and start to build the future; as long as were part of the ecosystem; after all, thats why this is blockchain 3.0

This cryptocurrency, Dogecoin: shit started as a joke back in 2013, right?actually a pretty solid crypto with a silly name attached to it running on a similar code as Litecoin without a cap so its very volatile/reliable & low exchange fees

@CoinDesk @SatoshiLite @LitecoinProject @CoinDesk you can swap Litecoin for $Beam in Beam Desktop Wallet a decentralized marketplace. Beam has Atomic Swaps for $BTC, $LTC, and $QTUM. Bring some LTC to the Beam community.

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Litecoin (LTC) Up $0.1 Over Past 4 Hours, Entered Today Down 0.18%; Price Base in Formation Over Past 90 Days - CFDTrading

Litecoin (LTC) Price Analysis: Fresh Rally To $50 Seems Likely – Live Bitcoin News

Litecoin price is rising again and trading above $44.00 against the US Dollar, similar to bitcoin. LTC price is likely to settle above $45.50 and it could rise towards $50.00 in the near term.

In the past few sessions, there was a steady rise in bitcoin, Ethereum, ripple, and litecoin against the US Dollar. Earlier, LTC price formed a strong support base near the $40.00 and $40.50 levels.

It started a fresh increase after it surpassed the $42.00 resistance level and the 55 simple moving average (4-hours). Moreover, there was a break above a significant bearish trend line with resistance near $42.30 on the 4-hours chart of the LTC/USD pair.

The pair even surged above the $44.00 and $45.00 levels. A high is formed near $45.65 and the price is currently consolidating gains near the $45.50 level. It corrected below the 23.6% Fib retracement level of the recent wave from the $42.87 low to $45.65 high.

On the downside, there is a strong support forming near the $44.20 and $44.00 levels. The 50% Fib retracement level of the recent wave from the $42.87 low to $45.65 high is also at $44.26.

If there is a downside break below the green zone at $44.00, there is a risk of a larger correction towards the $43.20 level. The main support is now forming near the $42.00 level.

Conversely, the price may perhaps start a fresh increase above the $45.50 and $46.00 levels. A successful close above the $46.00 level could open the doors for a push towards the next major hurdle at $50.00 in the near term.

Litecoin Price

Looking at the chart, litecoin price is clearly trading near a crucial resistance at $45.50. It could either continue to rise towards the $50.00 level or it might start a major downside correction towards the $42.20 level.

4 hours MACD The MACD for LTC/USD is slowly losing momentum in the bullish zone.

4 hours RSI (Relative Strength Index) The RSI for LTC/USD is currently correcting lower towards the 60 level.

Key Support Levels $44.20 and $42.20.

Key Resistance Levels $45.50 and $50.00.

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Litecoin (LTC) Price Analysis: Fresh Rally To $50 Seems Likely - Live Bitcoin News

NIH Funds Research to Understand How Genomics of Diverse Populations Affect Clinical Care – AJMC.com Managed Markets Network

Polygenic risk scores, which evaluate disease risk based on DNA variants, have previously been based almost entirely on patients who had European ancestry.

The project, Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network, will build upon work of the existing eMERGE Network, and help these institutions recruit a higher percentage of patients from diverse ethnic backgrounds. The goal is to serve patients who are typically underrepresented in clinical trials or who typically have poor clinical outcomes.

NHGRI funds eMERGE, which brings together DNA biorepositories with electronic health record (EHR) systems to allow high-throughput genetic research to advance personalized medicine. While much of this kind of work is associated with cancer research, eMERGE and the grants awarded in the new round of funding will work to advance protocols that will determine care models for diabetes and cardiovascular disease and determine who is at risk for Alzheimer disease.

The challenge of bringing diversity to clinical trials has been well-documented in the scientific literature in recent years. A 2016 workshopat the European Society of Human Genetics explored the need to address disparities by engaging communities that been historically underrepresented in genomics research; without data from these populations, interpreting genetic testing results would be difficult when these patients sought care, and pathways based on clinical trials might not produce the same outcomes in these populations.

Where the Money Goes

In addition to the $61 million to the 10 sites, $13.4 million will go to the eMERGE Network Coordinating Center at Vanderbilt University.

The 10 sites will be in 2 categories. The first group, to include Mayo Clinic, Rochester,Minnesota; Vanderbilt University Medical Center, Nashville, Tennessee; Brigham and Womens Hospital, Boston; and Northwestern University, Chicago, will seek 10,000 patients, of which at least 35% should be from underrepresented groups.

The second set of locations, called enhanced diversity clinical sites, will seek 15,000 patients, of which 75% must be from diverse groups. These are the University of Alabama, Birmingham; Icahn School of Medicine at Mount Sinai, New York City; Cincinnati Children'sHospital Medical Center; Columbia University, New York City; Childrens Hospital of Philadelphia; and University of Washington Medical Center, Seattle.

Officials for Childrens Hospital of Philadelphia (CHOP) noted the specific requirements of this round of funding called for enrolling at least 2500 new participants who had not been previously involved with the hospitals Center for Applied Genomics (CAG), of which 75% must be African American.

The Center for Applied Genomics and the National Institutes of Health have had an excellent partnership within the eMERGE Network, and we are thrilled to continue to build upon the valuable work that we have been able to achieve so far with particular emphasis on resolving diseases in diverse patient populations and minority groups, Hakon Hakonarson, MD, PhD, director of the CAG at CHOP and principal investigator of the program, said in a statement. The primary goals of this program are to identify disease risks faced by patients and their families and to determine the most appropriate actions we can take to improve health outcomes. The program specifically focuses on African American children and their families, who will constitute 75% of participants.

Polygenic risk scores, which evaluate disease risk based on DNA variants, have previously been based almost entirely on patients who had European ancestry. Investigators have seen a need to incorporate data from patients from non-European ancestry into risk scores, as well as those who have clinical and lifestyle characteristics seen in the real world, such as higher body mass index (BMI), alcohol use, elevated blood glucose levels, and other factors that affect a persons risk level.

The eMERGE Network, launched in 2007, first collected electronic health record data to address this problem. The sites that will proactively collect data over the next 5 years will add new data to incorporate into risk calculations.

The goal is to develop protocols to estimate risk for common, complex diseases, such as coronary heart disease, diabetes, or Alzheimers disease, and incorporate health management recommendations for clinicians into the EHR using the Fast Healthcare Interoperability ResourceStandard, which spells out how health information is to be shared electronically.

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NIH Funds Research to Understand How Genomics of Diverse Populations Affect Clinical Care - AJMC.com Managed Markets Network

Parasitic worms use their keen senses to wriggle through their hosts – University of Wisconsin-Madison

Parasitic filarial nematodes infect hundreds of millions of people, causing diseases such as river blindness and lymphatic filariasis, which can lead to elephantiasis, a severe swelling of the limbs.

Mosquitoes spread the parasitic worms, which engage in sophisticated migrations within their insect and mammal hosts. One worm, Brugia malayi, starts in the mosquitos gut, migrates to its flight muscles, then to its mouth. In its human host, the worm travels between the lymphatic system and the blood. Researchers have little idea how the nematodes achieve these nomadic lifestyles that are crucial for their survival.

Researchers prepare to inject an anaesthetized mosquito infected with parasitic Brugia malayi nematodes with gene-disrupting molecules to study how the nematodes rely on chemical sensation to migrate within their hosts. Courtesy of Zamanian lab

In new research, University of WisconsinMadison scientists provide the first look at the genetic underpinnings of the worms migration through their hosts. They identified two genes the nematodes use to respond to cues in their host environment. When the genes are disrupted, the worms are lost and less effective at infecting their hosts.

The genes are part of the nematodes chemosensation network, a combination of chemical-sensing proteins and nerve cells that let the parasites detect and respond to molecules in their environment. Because these responses are key for the nematodes complex life cycle, theyre a potential target for future treatments.

Were hopeful that a better understanding of how worms are transmitted between hosts and move within them may lead to new approaches for parasite treatment and control, says Mostafa Zamanian, a professor of pathobiological sciences in the UWMadison School of Veterinary Medicine and senior author of the report. The work was published in June in the journal PLOS Biology.

All animals use chemosensation. Its what allows a bee to follow the scent of a flower or a human to track down the aroma of baking cookies. The Zamanian lab figured that filarial nematodes used the same system to travel to the right part of their mosquito and human hosts at the right time by following specific chemical signatures their hosts produce.

To test this idea, the researchers mined over 40 parasite genomes to identify sensory genes in filarial parasites. Then they measured the expression of chemosensory genes throughout the parasites life cycle. They looked at chemoreceptors proteins that detect a specific signal during distinct stages of the parasites life cycles within human and mosquito hosts, when the parasites migrate to different tissues.

Mostafa Zamanian

Nicolas Wheeler

We saw chemoreceptors turned on and turned off at very specific time points, likely to help the nematodes get to the right destination at the right time, says Nicolas Wheeler, a postdoctoral researcher in the Zamanian lab and lead author of the new study.

The researchers tested whether disrupting the chemosensation network would impair the worms ability to migrate within and infect their hosts. They singled out two genes known to act as messengers for chemosensation in distantly related nematodes: OSM-9 and TAX-4.

To test OSM-9s function, they exposed the nematodes to the OSM-9-disrupting chemical nicotinamide at different stages of their life cycles. When these nicotinamide-laced worms were fed to mosquitoes, the insects ended up infected with 20 to 40 percent fewer parasites. Those nematodes that did survive in the mosquitoes were worse at migrating to the insects flight muscles compared to nematodes with normally functioning OSM-9.

The researchers also extracted larvae from mosquitoes during the stage when they can infect humans and exposed them to nicotinamide. In a petri dish experiment, the larvae became less likely to move toward chemical signals in mammalian blood. The results of the nicotinamide experiments suggested that OSM-9 is key for helping the worms navigate.

The filarial nematode Brugia malayi during the larval life stage when it can infect humans, where the parasite can cause severe swelling in the limbs known as elephantiasis. Courtesy of Zamanian lab

Using another system, the research team was able to disrupt both OSM-9 and TAX-4 while the nematodes were developing within their mosquito hosts. The researchers had to inject hundreds of mosquitoes by hand with molecules tailored to disrupt each gene finicky, time-consuming work.

Because the mosquitoes were infected with the parasites and potentially able to transmit them, the researchers had to don head-to-toe protective clothing to avoid getting bitten. Then they tested how well the nematodes could respond to chemical signatures in mammals.

The filarial nematode Brugia malayi during the lifestage when it is taken up by mosquitoes feeding on infected humans. In mosquitoes, the parasite must travel from the insects gut to its flight muscles and eventually its mouth to make it back to human hosts. Courtesy of Zamanian lab

It was worth it in the end, because we were able to show both OSM-9 and TAX-4 are involved in the infective larvas ability to crawl toward (host signals in the blood), says Wheeler. These are the first two genes to be linked to migratory behavior in these parasitic nematodes.

There are effective treatments against filarial parasites, but the complex drug regimens have potentially severe side effects, and the nematodes have developed drug resistance. There is also growing evidence that sensory systems play an important role in how parasites respond to existing antiparasitic drugs. A better understanding of how the worms detect chemical signatures and find their way within hosts could one day help researchers disrupt these critical migrations, potentially bolstering treatment.

This is a starting point, says Wheeler.

This work was funded in part by the National Institutes for Health (grants K22AI125473 and R01AI151171).

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BridgeBio Pharma’s Phoenix Tissue Repair to Highlight Interim Phase 1/2 Study Data in a Presentation at the Society for Pediatric Dermatology’s 45th…

BOSTON, July 10, 2020 (GLOBE NEWSWIRE) -- BridgeBio Pharma, Inc. (Nasdaq: BBIO) affiliate Phoenix Tissue Repair (PTR) today announced an upcoming presentation of interim data from an ongoing Phase 1/2 study of PTR-01 (BBP-589), an intravenously-administered recombinant collagen 7 protein replacement therapy for patients with recessive dystrophic epidermolysis bullosa (RDEB). The presentation will be made during the Society for Pediatric Dermatologys (SPD) 45th Annual Meeting, to be held virtually July 10-12, 2020.

The poster presentation, which includes safety and tolerability data observed so far in patients enrolled in cohorts 1-3, will be delivered by Anna L. Bruckner, MD, associate professor of dermatology and pediatrics at University of Colorado School of Medicine. The pre-recorded presentation will be available online to meeting registrants until December 31, 2020. The poster will also be available on the Phoenix Tissue Repair website.

Details for the presentation are below:

Title: Interim update from a Phase 1/2 trial examining the safety and tolerability of PTR-01, a collagen 7 protein replacement therapy, in patients with recessive dystrophic epidermolysis bullosaPresenter: Anna L. Bruckner, MD

AboutDystrophic Epidermolysis Bullosa (DEB)DEB is a rare genetic disorder symptomatic from birth that is caused by mutations in the gene for a protein called collagen type VII (C7). The C7 protein is essential for the formation of anchoring fibrils, structures which connect the epidermis and dermisthe uppermost two layers of the skin. Patients with the recessive form of DEB (RDEB) tend to have particularly severe symptoms due to severe insufficiency of functional C7. Symptoms include extreme skin and mucosal fragility that present as recurrent, painful blistering and scarring of the skin, as well as ulcerations of the mouth, tongue and dental caries. In addition to the cutaneous and oral symptoms, severe forms are associated with erosions and scarring of mucous membranes of the eye, esophagus, genitals and anus. Joint contractures, mutilating deformities of hands and feet, malnutrition, growth retardation, recurrent infections and a significantly increased risk for squamous cell carcinoma are also common. There are currently no approved disease-modifying therapies for any form of DEB, and the standard of care focuses on wound and pain management.

About Phoenix Tissue Repair and PTR-01Phoenix Tissue Repair is aBoston-based company that is an affiliate of BridgeBio Pharma, and is focused on advancing a novel systemic treatment for recessive dystrophic epidermolysis bullosa (RDEB).PTR-01 is an investigational protein replacement therapy which uses a recombinant collagen type VII (rC7) for the treatment of RDEB. PTR-01 is designed to be systemically available through intravenous delivery. Phoenix Tissue Repair acquired worldwide rights to PTR-01 in 2017. Preclinical studies of PTR-01 have demonstrated C7 staining in basement membranes withde novoanchoring fibril formation and improved survival in models of RDEB.

PTR-01 has been granted Orphan Drug Designation by the U.S. Food and Drug Administration and the European Medicines Agency.

About BridgeBioPharma, Inc.BridgeBio is a team of experienced drug discoverers, developers and innovators working to create life-altering medicines that target well-characterized genetic diseases at their source. BridgeBio was founded in 2015 to identify and advance transformative medicines to treat patients who suffer from Mendelian diseases, which are diseases that arise from defects in a single gene, and cancers with clear genetic drivers. BridgeBios pipeline of over 20 development programs includes product candidates ranging from early discovery to late-stage development. For more information, visit bridgebio.com.

Forward-Looking StatementsThis press release contains forward-looking statements. All statements contained herein other than statements of historical fact constitute forward-looking statements, including statements relating to expectations, plans, and prospects regarding Phoenix Tissue Repair's clinical development plan, clinical trial results, timing and completion of clinical trials, and ability to take advantage of expedited FDA review for PTR-01. These forward-looking statements are subject to a number of risks, uncertainties and assumptions, including, but not limited to, Phoenix Tissue Repair's ability to advance PTR-01 in clinical development in accordance with its plans, the results from any clinical trials and nonclinical studies of PTR-01, and the nature of Phoenix Tissue Repair's interactions with regulatory authorities. Moreover, Phoenix Tissue Repair operates in a very competitive and rapidly changing environment in which new risks emerge from time to time. These forward-looking statements are based upon the current expectations and beliefs of Phoenix Tissue Repair's management as of the date of this release and are subject to certain risks and uncertainties that could cause actual results to differ materially from those described in the forward-looking statements. All forward-looking statements in this press release are based on information available to Phoenix Tissue Repair as of the date hereof, and Phoenix Tissue Repair disclaims any obligation to update these forward-looking statements except as required by law.

Investor Relations Contact:Mike Mangone, Ph.D.Vice President, Business Development & Corporate Strategy857-449-0970info@phoenixtissuerepair.com

Media Relations Contact:Carolyn HawleyCanale Communications(619) 849-5382carolyn@canalecomm.com

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Genetic testing and hitching a ride with the British; In The News for July 10 – Medicine Hat News

By The Canadian Press on July 10, 2020.

In The News is a roundup of stories from The Canadian Press designed to kickstart your day. Here is whats on the radar of our editors for the morning of July 10

What we are watching in Canada

OTTAWA The Supreme Court of Canada is slated to rule this morning on the constitutionality of a federal law that forbids companies from making people undergo genetic testing before buying insurance or other services.

The Genetic Non-Discrimination Act also outlaws the practice of requiring the disclosure of existing genetic test results as a condition for obtaining such services or entering into a contract.

The act is intended to ensure Canadians can take genetic tests to help identify health risks without fear they will be penalized when seeking life or health insurance.

The law, passed three years ago, is the result of a private members bill that was introduced in the Senate and garnered strong support from MPs despite opposition from then-justice minister Jody Wilson-Raybould.

The Quebec government referred the new law to the provincial Court of Appeal, which ruled in 2018 that it strayed beyond the federal governments jurisdiction over criminal law.

The Canadian Coalition for Genetic Fairness then challenged the ruling in the Supreme Court of Canada, which heard the appeal last October.

Also this

OTTAWA Canadian troops are being forced to hitch a ride with the British military to get to and from Latvia due to a shortage of working planes.

A CC-150 Polaris was to carry about 120 Canadian soldiers to Latvia on Wednesday and fly back with a similar number of returning troops.

Yet the Defence Department says those plans changed after a problem was found with the planes landing gear, which is when the military asked the British for help.

The Air Force has three Polaris capable of ferrying personnel to different parts of the world but the Defence Department says the other two were unavailable.

One is currently ferrying troops to and from the Middle East while the third which normally serves as the prime ministers plane is out of commission until at least January after a hangar accident last October.

Defence Department spokeswoman Jessica Lamirande says the British plane took off with the 120 departing troops on Thursday and will return with a similar number of soldiers in the coming days.

What we are watching in the U.S.

International students worried about a new immigration policy that could potentially cost them their visas say they feel stuck between being unnecessarily exposed during the coronavirus pandemic and being able to finish their studies in the United States.

The students from countries such as India, China and Brazil say they are scrambling to devise plans after federal immigration authorities notified colleges this week that international students must leave the U.S. or transfer to another college if their schools operate entirely online this fall.

Some say they are considering the possibility of returning home or moving to Canada.

What we are watching elsewhere in the world

SEOUL The sudden death of the Seoul mayor is triggering an outpouring of public sympathy but also questions about his behaviour.

Park Won-sun was found dead in the South Korean capital, hours after his daughter reported him missing.

Media reports say one of his secretaries lodged a complaint with police over his alleged sexual harassment.

Many mourn Parks death, while others worry sympathy for him could lead to a criticism of the woman who filed the complaint.

Despite gradually improvements in womens rights in recent years, South Korea remains a male-centred society.

Today in 1912

Montreals George Hodgson won Canadas first Olympic swimming gold medal. He set a world record of 22 minutes flat in the 1,500-metre freestyle at the Games in Stockholm. That record lasted 11 years. Four days later, Hodgson won the 400-metre freestyle. Canada did not capture another Olympic swimming title until 1984.

The Canadian economy

Statistics Canada is set this morning to give a snapshot of the job market as it was last month as pandemic-related restrictions eased and reopenings widened.

Economists expect the report will show a bump in employment as a result, further recouping some of the approximately three million jobs lost over March and April.

Financial data firm Refinitiv says the average economist estimate for June is for employment to increase by 700,000 jobs and the unemployment rate to fall to 12.0 per cent.

The unemployment rate in May was a record-high 13.7 per cent, a far turn from the record low of 5.5 per cent recorded in January.

The Bank of Canada and federal government say the worst of the economic pain from the pandemic is behind the country, but Canada will face high unemployment and low growth until 2021.

The economic outlook released by the Liberal government Wednesday forecasted the unemployment rate to be 9.8 per cent for the calendar year, dropping to 7.8 per cent next year based on forecasts by 13 private sector economists.

This report by The Canadian Press was first published July 10, 2020.

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Genetic testing and hitching a ride with the British; In The News for July 10 - Medicine Hat News

A WHO-led mission may investigate the pandemic’s origin. Here are the key questions to ask – Science Magazine

An emergency response team on 11 January at work in the Huanan Seafood Wholesale Market in Wuhan, China, initially said to be the source of COVID-19.

By Jon CohenJul. 10, 2020 , 4:30 PM

Science's COVID-19 reporting is supported by the Pulitzer Center and the Heising-Simons Foundation.

The two-person team from the World Health Organization (WHO) traveling to China today to address the origin of the COVID-19 pandemic is unlikely to come home with answers. Rather, the duoan epidemiologist and an animal health expert whose names have not been releasedwill discuss with Chinese officials the scope of alarger international mission later, according to a WHO statement.

But this initial trip offers real hope that the mystery of the virus origins, which has become a political powder keg and the subject of countless conspiracy theories, will finally be investigated more thoroughly and transparently. (A similar WHO-led mission to examine how China was handling its fight against the virus, launched after weeks of diplomatic wrangling, returned in February with a surprising wealth of information.)

Science must stay open to all possibilities about the pandemics origins, Mike Ryan, executive director of WHOs Health Emergencies Programme, said at a press conference on 7 July. We need to lay out a series of investigations that will get the answers that Im sure the Chinese government, governments around the world, and ourselves really need in order to manage the risk going forward into the future.

Questions range from hunting for animals that might harbor the virus to examining the possibility that it came from a laboratory. There are plenty of details to investigate, and it could be a long road. Origin riddles for other new infectious diseases often took years to solve, and the route to answers has involved wrong turns, surprising twists, technological advances, lawsuits, allegations of cover ups, and high-level politics. Determining how a pathogen suddenly emerges in people requires a lot of sleuthing, but past successes offer clues of where to look for new insights, as do the few data points that now exist for SARS-CoV-2, the virus that causes COVID-19.

The initial, tidy origin story told by health officials in Wuhan during the first few weeks of January was that a cluster of people connected to a seafood market developed an unusual pneumonia, and that the outbreak stopped after the market was closed and disinfected. But confusion about the origin of the novel coronavirus identified in Wuhan patients arose when researchers published the first epidemiologic studies of the citys outbreak:Four of the first five casesconfirmed to have SARS-CoV-2 infections had no link to the market.

Soon, other theories emerged. Some believe its no coincidence that the city is host to the Wuhan Institute of Virology (WIV), home to leading bat coronavirus researcher Shi Zheng-Li. Her group, one of the first to isolate and sequence SARS-CoV-2, has trapped bats in the wild for 15 years, hunting for coronaviruses to help identify pandemic threats. In theirfirst report about the new virus, the scientists described a bat coronavirus in their collection that was 96.2% similar to SARS-CoV-2.

U.S. President Donald Trump early on endorsed speculation that the virus entered humans because of an accident at WIV. Amore contentious theoryis that the lab created the virus. (Researchers at the lab insist neither scenario has any merit, and evolutionary biologists elsewhere have argued the virus shows no evidence of having been engineered.)

The most popular hypothesis is that SARS-CoV-2 spread into humans from an intermediate host, an animal species susceptible to the virus that acted as a bridge between bats and humans. In the case of severe acute respiratory syndrome (SARS), civets turned out to play that role for the responsible coronavirus. For Middle East respiratory syndrome (MERS), also a coronavirus disease, itquickly became clearcamels were the culprit because highly similar viruses were found in the animals and people caring for them.

Chinese officials have reported conducting tests for SARS-CoV-2 at the Wuhan seafood market but what they foundremains sketchy. Chinas state-run news agency, Xinhua, said environmental samples tested positive for the virus in a zone of the market that sold wildlife, but the report had no details about the results or even a list of the species for sale. Other studies have discovered similarities between SARS-CoV-2 and a coronavirus found in pangolins, an endangered species that eats ants, but the pangolin virus is more divergent genetically from SARS-CoV-2 than the closest bat virus and theres no evidence pangolins or their scalesused in traditional Chinese medicinewere sold at the market.

Some more fringe theories still suggest SARS-CoV-2 came fromsnakes,cometary debris, or aU.S. Army lab.

So, assuming WHOs team and the Chinese government work out a deal for an international mission to study the pandemics origins, where would it start? Here are some key questions that need answers.

Scientists realized camels were the source of Middle East respiratory syndrome when highly similar viruses were found in the animals and people caring for them.

Another outstanding question is whether Shis team or other researchers in Wuhan manipulated bat viruses in gain-of-function experiments that can make a virus more transmissible between humans. In 2015, Shi co-authored a paper that made a chimeric SARS virus by combining one from bats with a strain that had been adapted to mice. Butthat workwas done at the University of North Carolina, not in Wuhan, and in collaboration with Ralph Baric. Did Shis group later carry out other gain-of-function studies in Wuhanand if so, what did they find?

Finally, diplomatic cablesfrom the U.S. Embassy in Beijing in 2018 warned that a new, ultra-high security lab at WIV had a serious shortage of appropriately trained technicians and investigators. Did Shis team ever work with coronaviruses in that lab, and, if so, why?

If history repeats itself, it might take yearsor even decadesto crack this case. Scientists havent unequivocally identified Ebolas source 45 years after its discovery. But the key, time and again, to clarifying the origins of emerging infectious diseases is unearthing new data. WHOs push to organize the probe promises to, at the very least, accelerate what has been a plodding pursuit for answers.

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Scientists need to track genetic diversity of COVID-19 for effective vaccine: U of M study – CTV News Winnipeg

WINNIPEG -- A new study out of the University of Manitoba has determined that in order for the creation of an effective COVID-19 vaccine, experts must track the genetic diversity of the virus

The work, conducted by researchers at the Rady Faculty of Health Sciences and a virology lab at Universidad de Concepcin in Chile, also found that if scientists dont monitor how the virus is changing in different parts of the world, the testing could produce false negative results. Dr. Carlos Farkas, a postdoctoral researcher in pharmacology and therapeutics for the Max Rady College of Medicine and the Research Institute in Oncology and Hematology, was the studys lead author.

To conduct the study, the research team used datasets to look at whole genome sequencing samples from people infected before March 27 with the virus that causes COVID-19.

According to a news release from the university, this team was the first to combine genomic sequencing data from two worldwide sources in order to detect variants by geographic region. The group found 146 different variants.

Dr. Jody Haigh, co-author and associate professor of pharmacology and therapeutics and a senior scientist at the Research Institute in Oncology and Hematology, said one of the major findings was that samples from Washington had a distinctive footprint of viral sequence changes.

About 39 per cent of Washington State samples had this footprint. Asian and European samples were more diverse in terms of changes in viral sequence, but their footprints were clearly different from those in the U.S. samples, Haigh said in the release.

The researchers noted when labs test for SARS-CoV-2 (the virus that causes COVID-19), they use small pieces of DNA that bind to the viral sequence and amplify viral RNA/DNA.

Farkas said in order for a robust positive test result, the DNA needs to exactly match the viral sequence.

If researchers design these primers to bind to regions of the virus that they dont realize have changed in a particular population, there may be poor amplification and the result can be false negatives, Farkas said.

The study did find some changes in viral sequence in regions of the virus where the DNA was supposed to bind, which could explain why there have been some false negative testing results.

Because SARS-CoV-2 is changing rapidly, researchers should be aware of its current local viral footprints in order to design DNA primers that dont bind to regions of the virus that have changed. Other regions of the virus that dont show these changes should be used for designing primers, Haigh said.

The research team hopes its work will impact COVID-19 testing and vaccine development.

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Scientists need to track genetic diversity of COVID-19 for effective vaccine: U of M study - CTV News Winnipeg