CAL to resume flights between Jamaica and Bahamas on July 31 – Jamaica Observer

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KINGSTON, Jamaica Caribbean Airlines says it will re-start flight operations between Kingston, Jamaica and Nassau, Bahamas from July 31.

The airline said the re-introduction of this weekly service is part of its phased roll out of its commercial operations from its hub in Jamaica. The flight will operate each Friday leaving Kingston at 12.35 pm.

The airline has also announced the restart of twice weekly flights between Kingston in Jamaica, Antigua and Barbados effective July 25. This comes after daily flights to/from Kingston and New York were resumed on July 6.

Additionally, customers can now book daily non-stop flights between Jamaica and Miami, as well as twice weekly services from Jamaica to Toronto, available Wednesdays and Sundays.

Now you can read the Jamaica Observer ePaper anytime, anywhere. The Jamaica Observer ePaper is available to you at home or at work, and is the same edition as the printed copy available at http://bit.ly/epaperlive

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CAL to resume flights between Jamaica and Bahamas on July 31 - Jamaica Observer

TINY GONZALO EXPECTED TO BRING TROPICAL STORM CONDITIONS TO THE SOUTHERN WINDWARD ISLANDS ON SATURDAY – Magnetic Media

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#Nassau, Bahamas Bahamas Department of Meteorology AT 5AM EDT, THE CENTER OF TROPICAL STORM GONZALOWAS LOCATED NEARLATITUDE 10.0 NORTHANDLONGITUDE 51.8 WEST,OR ABOUT 645 MILES EAST OF THE SOUTHERN WINDWARD ISLANDS.

GONZALO ISMOVING TOWARD WEST NEAR 14 MILES PER HOUR. A WESTWARD TO WEST-NORTHWESTWARD MOTION WITH AN INCREASE IN FORWARD SPEED IS EXPECTED THROUGH THE WEEKEND.ON THE FORECAST TRACK, THE CENTER OF GONZALO WILL APPROACH THE SOUTHERN WINDWARD ISLANDS TONIGHT, MOVE ACROSS THESE ISLANDS SATURDAY, AND INTO THE EASTERN CARIBBEAN SEA ON SUNDAY.

MAXIMUMSUSTAINED WINDSARE NEAR 60 MILES PER HOURWITH HIGHER GUSTS. SOME STRENGTHENING IS FORECAST DURING THE NEXT DAY OR TWO, AND THERE IS STILL A CHANCE THAT GONZALO COULD BECOME A HURRICANE BEFORE REACHING THE WINDWARD ISLANDS. WEAKENING IS EXPECTED AFTER GONZALO MOVES INTO THE CARIBBEAN SEA, AND THE CYCLONE IS EXPECTED TO DISSIPATE BY THE MIDDLE OF NEXT WEEK.

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TINY GONZALO EXPECTED TO BRING TROPICAL STORM CONDITIONS TO THE SOUTHERN WINDWARD ISLANDS ON SATURDAY - Magnetic Media

Protest at Office of Bahams PM; rejecting plan to detain illegal Haitians on Ragged Island – Magnetic Media

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#Nassau, Bahamas July 24, 2020 Ragged Islanders today staged a socially distanced protest at the Office of the Prime Minister in Nassau, confirming their outrage with the decision to detain intercepted Haitian migrants at the Royal Bahamas Defence Force base on the island.

During House of Assembly debate on Thursday, Chester Cooper, the Member of Parliament for the island called the decision a ridiculous plan which should be reversed.

I protest it in the strongest possible terms and I ask the government to reverse this plan forthwith, because the people of Ragged Island have started wondering why you despise them so.

This is contemptuous and I ask you to reverse it because the people of Ragged Island will not take kindly to it.

Communication from the Defence Force explained, they jointly foiled a human smuggling operation.

On Tuesday 21 Ju1y just before 10:00 a.m., HMBS P-44 coxswained by Chief Petty Officer Acadia Smith, located the 27-foot, white cabin cruiser anchored just off the northeastern point of Great Isaacs, north of Bimini, where it had run aground. When it became evident that a migrant smuggling operation was underway, the vessel and its occupants12 females (1 pregnant), 9 males and 2 infants, all believed to be of Haitian descent, were detained.

Unmoved by the promised to repatriate the group as soon as is possible, Ragged Islanders demonstrated with placards conveying a string of compelling messages.

Placards decried: First you deem Ragged Island inhabitable. Now Dumping Ground and another which read: Keep Ragged Island Covid FREE.

Islanders, who remain displaced due to Hurricane Irma are reportedly incensed by a decision to detain illegal migrants in their home island and are restating their desperate desire to return home.

Additionally, the government clinic on Ragged Island remains out of commission since the storm in September 2017. The Member of Parliament used his time in parliament to outline the many reasons the Government must find an alternative detainment plan for the 21 Haitians, which includes children and a pregnant woman.

If it is the intention to land temporarily and then deport, this is a terrible place to do it because the logistics are horrible, he continued.

There is no bus, there are no vans. There are no proper facilities at the defense force base at Gunpoint.

It is said the migrants are temporarily detained at the Defence Force base on Ragged Island.

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Protest at Office of Bahams PM; rejecting plan to detain illegal Haitians on Ragged Island - Magnetic Media

Quantum Computing: Navigating Towards The Future Of Computers – Analytics Insight

Computing power has reached its saturation point. If we continue following the same path soon, we may not have enough power to run the machines of the world. The solution to this lies in quantum computing. The origins of quantum computing go back in 1981 when renowned physicist Richard Feynman asked in a Massachusetts Institute of Technology conference that, Can we simulate physics on a computer? While it is not totally based on physics, quantum computing does work on the principles of quantum mechanics. Here it uses two properties called superposition and entanglement.

Current conventional computer systems are built around the idea of binary bits and Boolean logic. A bit can be physically represented as a switch with a value of 0 (off) or 1 (on). When these switches are connected using Boolean logic gates (and, or, xor, and others) they can perform all the complex operations of a modern microprocessor. In contrast, quantum computer use qubits (quantum bits) can also be in both states at the same time, a quantum property called superposition. In addition, qubits are also capable of pairing, which is known as entanglement. Here, the state of one qubit cannot be described independently of the state of the others that allows instantaneous communication. As per anIDC report, 25 percent of the Fortune Global 500 will gain a competitive edge from quantum computing by 2023.

Meanwhile, tech giants like Google, Microsoft, and IBM are battling to be the first to make a working, practically useful quantum computer. Every month there are extensive updates from these companies about their work. Recently Google had announced its quantum computer (which uses quantum annealing) is 100 million times faster than any classical computer in its lab. Further, the interest in quantum computing has been mirrored by investments in this field by players from a broad array of industries.

Quantum computers have four fundamental capabilities that differentiate them from todays conventional computers:

1. quantum simulation, in which quantum computers model complex molecules;

2. optimization (that is, solving multivariable problems with unprecedented speed);

3. quantum artificial intelligence, with better algorithms that could transform machine learning across industries as diverse as pharma and automotive;

4. prime factorization, which could revolutionize encryption.

These advanced computers are predicted to solve previously unapproachable problems, creating valuable solutions for industry and will disrupt current techniques. For instance, NASA is looking at using quantum computing for analyzing the enormous amount of data they collect about the universe, as well asresearch better and safer methods of space travel.Auto manufacturer leader, Volkswagen is using quantum computers to develop battery, transportation, and self-driving technology. It can be utilized to boost security since it can enhance the accuracy of measurements and enable new modalities for sensors and measurements.For example, it can accurately detect masses moving underwater, such as submarines.

Oil and gas companies can employ quantum computing to calculate the ways how atoms and molecules can be configured to protect equipment from corrosion. Even in pharmaceuticals, the discovery of new drugs, minimal development time, potential ways to synthesize new compounds are possible due to this technology. In the chemicals industry, it is used to provide a better understanding of catalytic reactions, reducing the cost of industrial processes. Quantum entanglement has also led to the possibility of quantum teleportation.

It is important to note that quantum computers are very fragile. Any vibration will impact the atoms and cause decoherence. Also, at present, quantum computers need highly sophisticated hardware and supporting infrastructure. For this, some of the existing models use superconductivity to create and maintain a quantum state. This implies that qubits must be kept at a temperature near absolute zero using a dilution refrigerator. This is why theinside of D-Wave Systems quantum computeris -460 degrees Fahrenheit. So, companies may need a cloud model to access quantum services instead of installing their own version of quantum computers on-premises. Therefore, not all can have their quantum systems, at least not in the near future.

Moreover, people need to realize that while quantum computers are the future, but they do not replace the standard ones either. Instead, they should be thought of as devices that enhance the usability of conventional general-purpose computers. According to this model, a core application is executed on a traditional computer that can also handle data storage and other infrastructure-related tasks. At the same time, the quantum part can be applied to deal with only the subset of the overall responsibility thats best suited to its particular strengths.

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Quantum Computing: Navigating Towards The Future Of Computers - Analytics Insight

Roundup: UK’s test and trace failing to contact thousands, France deploys AI-based cancer detection and more briefs – Healthcare IT News

FRANCE DEPLOYS AI-BASED CANCER DETECTION

AI-based cancer diagnostics company, Ibex Medical Analytics, and network of private pathology labs in France, Medipath, have announced the deployment of an AI-powered platform for cancer detection in pathology in France.

This coincides with a global decline in the number of pathologists and increased workloads.

The process of lab cancer diagnosis through a microscope is manual and thus prone to human error. Ibex offers a clinical grade, field proven AI-based solution that helps pathologists meet these challenges.

Medipath has completed deployment of Ibexs Galen Prostrate as part of its routine clinical practice.

With Ibexs CE-marked solution, an AI algorithm analyses prostate biopsies and raises alerts when discrepancies with the pathologists initial diagnosis are identified.

IRELAND DONATES CONTACT TRACING APP TO LINUX FOUNDATION

Irelands Health Service Executive (HSE) announced that is donating the code for COVID Tracker app as open source to the not-for-profit Linux Foundation.

This will enable jurisdictions worldwide to quickly build and deploy their own contact tracing apps.

The donated app has been named COVID Green.

NearForm will play a role as part of the Technical Steering Committee in managing the development and direction of COVID Green in the Linux Foundation.

The code is also being used in the app for Gibraltar and the upcoming apps for Northern Ireland, other jurisdictions in EMEA and some US states.

UKS TEST AND TRACE SYSTEM FAILING TO CONTACT THOUSANDS

The governments test and trace system is failing to contact thousands of people in areas with the highest infection rates in England, according to data obtained by the Guardian.

The data shows that in areas with the highest infection rates in England, the proportion of close contacts of infected being reached is far below 80%.

The governments Scientific Advisory Group for Emergencies (SAGE), agreed that at least 80% of contacts would need to isolate for an effective test and trace system.

Forty-seven per cent of at-risk people were contacted by test and trace in Luton, which has the sixth highest infection rate in England.

A Department ofHealth and Social Care spokesperson said: The service is working closely with local authorities across England to help manage local outbreaks. High quality data is critical to providing good public services and weve been providing increasingly detailed data to local directors of public health, helping them tackle local outbreaks and control this virus.

SLOVENIA BEGINS WORK ON CONTACT TRACING APP

This week, the Slovenian Ministry of Public Administration launched a tender for the creation of a contact tracingapp with a budget of 40,000.

The winner of the bid wasRSTEAM, one of six applicants of which only four met the budgetary preconditions set out by authorities.

The app will be based on Germanys Corona-Warn-App that has been in use for over a month.

The app that RSTEAM is set to develop is expected to be ready for launch on 1 August.

THE SHURI NETWORK'S FIRST ANNIVERSARY

The first network for black and ethnic minority women in digital health roles, the Shuri Network, celebrated its first anniversary this week.

One year ago, at the time of its launch, the network had 60 members but it has now grown to around 650 members.

The network was launched at Digital Health Summers Schools in 2019 to help increase visibility of black and minority ethnic women (BME) in NHS technology roles.

It has since worked to create spaces that give women of colour a platform to share experiences and propel forward the advancement and contributions of BME women in digital innovation.

The network has recently launched the Shuri Fellowship which will provide future leaders training opportunities to enhance their career. They have also partneredup with the Faculty of Informatics (FCI) to supplyShuri FCI bursaries for 15 members to cover the cost of their FCI membership.

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Roundup: UK's test and trace failing to contact thousands, France deploys AI-based cancer detection and more briefs - Healthcare IT News

Funding secured to further study of AI systems for cardiovascular health – Cardiac Rhythm News

Digital health and artificial intelligence (AI) company Eko has been awarded a US$2.7 million Small Business Innovation Research (SBIR) grant by the National Institutes of Health (NIH). The grant will fund the continued collaborative work with Northwestern Medicine Bluhm Cardiovascular Institute, Chicago, USA to validate algorithms to aid screening for pathologic heart murmurs and valvular heart disease.

Cardiovascular disease is the leading cause of death in the USA, and valvular heart disease often goes undetected because of the challenge of hearing murmurs with traditional stethoscopes, particularly in noisy or busy environments. A highly accurate clinical decision support algorithm that is able to detect and classify valvular heart disease will help improve accuracy of diagnosis and the detection of potential cardiac abnormalities at the earliest possible time, allowing for timely intervention, said James D Thomas, director of the Center for Heart Valve Disease at Northwestern Medicine and the clinical studys principal investigator. Our work with Eko aspires to extend the auscultatory expertise of cardiologists to more general practitioners to better serve our patient community, playing a pivotal role in growing the future of cardiovascular medicine.

Eko and Northwestern first announced their collaboration in March 2019 to provide a simpler, lower-cost way for clinicians to identify patients with heart disease without the use of screening tools such as echocardiograms which are typically only available at specialty clinics. By incorporating data from tens of thousands of heart patterns into the stethoscope and its algorithms, clinicians will have cardiologist-level precision in detecting subtle abnormalities from normal sounds, Eko said in a press release.

This SBIR award from the NIH underscores our vision to provide world-class cardiovascular care at the patients point of care, said Adam Saltman, chief medical officer at Eko. We believe that the integration of these deep learning algorithms into the Eko platform that is currently used by more than 1,000 institutions worldwide will lead to earlier diagnosis and better patient outcomes. Our mission is to change how cardiovascular disease is diagnosed, and as one of the first centres in the country to study AI and cardiovascular disease, Northwestern is an ideal partner to help us reach our goal.

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Funding secured to further study of AI systems for cardiovascular health - Cardiac Rhythm News

Riiid raises $41.8 million to expand its AI test prep apps – VentureBeat

Riiid, a Seoul, South Korea-based startup developing AI test prep solutions, today closed a $41.8 million pre-series D financing round, bringing its total venture capital raised to date to $70.2 million. CEO YJ Jang says the funding will be used to advance Riiids technology that offers personalized study solutions based on big data analysis, and to bolster the companys expansion across the U.S., South America, and the Middle East as it establishes an R&D lab Riiid Labs in Silicon Valley.

The pandemic has forced the shutdown of schools in countries around the world; cramped indoor classrooms are seen as a major threat vector. Despite inequities with regard to internet access and the widening achievement gap, educators believe the health pros outweigh the cons. Riiid, which offers its services exclusively online, has benefited from the shift. The company claims sales have grown more than 200% since 2017 as over a million users joined its community.

Riiids platform Santa is a mobile study aid for the Test of English for International Communication (TOEIC) English proficiency exam. (Unlike the better-known TOEFL or IELTS tests, which are used by Western universities and colleges as part of their admissions process, TOEIC is primarily used by employers to assess the English proficiency of prospective hires.) Leveraging AI and machine learning algorithms, Santa analyzes responses to predict scores and recommend personalized review plans. A meta-learning log with over 100 million pools of information supplies insights to support Santa, as well as Riiids other systems.

Santa primarily lives on the web, but its also available as a chatbot for smart speakers from Kakao. In Japan, Riiid teamed up with game developer KLab Langoo to design a mobile-optimized version of Santa.

According to Jang, the goal is to help achieve learning objectives through continuous evaluation and feedback rather than specific prep. The engineers called the app Santa because it collects data on student performance in the way that Santa Claus famously keeps track of childrens good deeds and bad, he told VentureBeat via email. We launched Santa in the Korean market, focusing on preparing students for the TOEIC exam because it was an easy target that would validate or invalidate our research findings. More than a million students in Korea and Japan have now used the Santa app and I can proudly report that it works. We raise scores by an average of 129 points out of a possible 990 on the TOEIC exam at a fraction of the time and cost it takes with traditional test-prep courses or personal tutors.

After launching Santa in Korea, Japan, and Vietnam, Riiid plans to pivot to backend curriculum solutions for companies, school districts, and education ministries. Earlier this year, the company published EdNet, a data set of all student-system interactions collected over two years by Santa. Riiid is also expanding its platform to standardized tests like the SAT and ACT, and it claims its signed memorandums of understanding with customers in the Middle East and U.S. (for example, private education center company Point Avenue) to develop programs for specific courses of study.

Riiids latest funding round included an investment from the state-run Korea Development Bank (KDB), NVESTOR, and Intervest, as well as from existing investor IMM Investment. According to LinkedIn data, the startup employs about 80 people.

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Riiid raises $41.8 million to expand its AI test prep apps - VentureBeat

3 Great Mysteries About Life on Mars – The New York Times

Mars is the most explored planet in the solar system other than Earth. With all of our robotic visitors there, weve discovered that it is a world far too dry, cold and irradiated to support the scheming humanoids or tentacled invaders once imagined by science fiction.

But our trips to Mars have opened a window into the deep past of the red planet, when conditions were far more conducive to life.

This summer, NASA will launch its latest rover, Perseverance, on a seventh-month journey to Mars. Like its predecessor, Curiosity, Perseverance will touch down in the remains of an ancient Martian lake bed. What it finds there along with missions launched by China and the United Arab Emirates could help us Earthlings understand what Mars was like as a young planet some four billion years ago, and whether life ever blossomed on its surface.

Its a serene image: A river flowing into an expansive lake that fills a crater basin. Waves lapping at the shoreline; sediment piling into a delta. A lake bed caked with clay.

This is the type of aquatic environment that might support life, and it was once a familiar sight on Mars.

The evidence for the lakes and rivers is incontrovertible, said Ken Farley, project scientist on Perseverance and a geochemist at the California Institute of Technology.

Although Mars was once a wet planet, there is substantial debate about the origins, extent and life span of its long-lost bodies of water.

For instance, early Mars might have been warmed by the gassy belches of active volcanoes, which thickened its atmosphere and caused Martian permafrost to melt. Cataclysmic asteroid impacts might have also unleashed 900-foot mega-tsunamis that flooded the planets terrain. Theres even disputed evidence that an ocean once covered its northern lowlands.

Was it weird, short, transient events, or was there an ocean? Dr. Farley said. I would say theres no consensus. Theres a lot of ideas out there, and we really need a lot more data to sort it out.

One major question concerns the longevity of Mars liquid water. Nobody knows how much time is required for life to emerge on a planet, including on Earth. But the odds of life forming get better the longer that stable bodies of water persist.

During Curiositys eight-year journey across Gale Crater, an ancient lake bed, the rover discovered sediments that suggest water was present for at least a few million years. Curiosity also detected organic compounds, key ingredients for life as we know it.

What weve learned from Curiosity suggests that Mars was habitable, said Dawn Sumner, a planetary geologist at the University of California, Davis, and a member of the Curiosity science team.

Of course, habitable does not necessarily mean inhabited. The surface of Mars is exposed to damaging solar and cosmic radiation, which could have reduced the odds of complex, multicellular life ever forming.

If life did exist on Mars, there would be a strong evolutionary force toward being resistant to radiation, Dr. Sumner said.

There are microbial extremophiles on Earth that can endure intense radiation, often healing their own DNA on the fly. So its not far-fetched to imagine that there might be Martian microbes that could tolerate an onslaught of radiation. Plus, they may have been able to retreat underground if conditions became particularly hostile at the surface.

The big lesson about life, from the revolution of being able to use DNA, is life is able to go everywhere, Dr. Farley said. It is amazing. It will fill every niche it can get itself into, and it will do it in a relatively short period of time.

The bygone oases of Mars are now mirages of a distant past, and modern Mars is a dried-up husk. Earth, in contrast, has been habitable to microbes for most of its life span and has positively burst at the seams with biodiversity for eons. Why did these sibling worlds experience such different outcomes?

As baby planets, Mars and Earth were each swaddled in two protective blankets: a relatively thick atmosphere and a strong magnetic field. Earth has held on to both comforts. Mars has neither.

Mars mysteriously lost its magnetic mojo billions of years ago. With no magnetic sheath to protect it from solar wind, the Martian atmosphere was stripped away over time, though it still maintains a thin shell of its past skies.

These changes have left Mars relatively inert for billions of years, while Earth reinvents itself through tectonic activity, atmospheric shifts and the ingenuity of life.

This is great news for Earthlings, as we need those processes to survive. Yet the sheer deadness of Mars over the past few billion years could make it easier to reconstruct its early history.

Life has been so successful on Earth that its hard to trace back its origin, Dr. Sumner said. On Earth, everything is covered with organic matter from modern life.

One of the really cool and exciting things about Mars is that, because it doesnt have plate tectonics, large parts of its surface have these super-old rocks, she continued. Its a good place to go to try to understand what an early planet would be like.

Robot explorers on Mars have turned up countless insights about the red planet, but they have never found clear-cut signs of creatures currently residing there. Life, at least as we know it on Earth, simply does not seem probable on the Martian surface.

If theres any life on Mars now, it needs at least some liquid water, Dr. Sumner said. The surface of Mars now is very dry. Just incredibly dry. If theres life on Mars now, it would be in the deep subsurface.

Theres some evidence that liquid water is locked away in subterranean reservoirs, so perhaps there are sunless ecosystems lurking there. If these habitats exist, they are beyond the direct reach of our rovers and landers.

Recent detections of methane and other gases in whats left of Mars atmosphere are a tantalizing potential signature, Dr. Farley said, bolstering speculation about subterranean Martians. Many microbes on Earth produce methane, so it is possible that whiffs of the gas on Mars could be traced to alien life-forms deep underground.

Curiosity, which is equipped with a methane-sensitive spectrometer, has compounded the mystery by recording weird spikes of the gas at the Martian surface that remain unexplained.

Unfortunately, the satellites orbiting the red planet have not been able to provide backup for these readings, and the new NASA and Chinese rovers on the red planet may not be able to solve the puzzle.

Methane can also be created by a wide range of natural processes that have nothing to do with life. Some experts, like Dr. Sumner, say that the presence of the gas on Mars is not a surprise because it has all the geological processes it needs to produce the gas without life.

The discovery of life on Mars, either in the form of ancient fossils or subterranean reservoirs, would be one of the most momentous breakthroughs in human history. At last, we would have another example of a living planet, even if it only flourished in the past, implying that, at the very least, life can strike twice in the universe.

But even if we never find Martians, Mars is a place we can go to answer some of the questions about life on Earth, Dr. Sumner said. The red planet remains an eerie time capsule of the era when life first sprouted on our own world, and the direction it could have gone had all the factors that made our world possible not turned out just the right way.

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3 Great Mysteries About Life on Mars - The New York Times

The genetic basis of bats superpowers revealed – YubaNet

July 23, 2020 For the first time, the raw genetic material that codes for bats unique adaptations and superpowers such as the ability to fly, to use sound to move effortlessly in complete darkness, to survive and tolerate deadly diseases, to resist ageing and cancer has been fully revealed.

Bat1K (Bat1K.com), a global consortium of scientists dedicated to sequencing the genomes of every one of the 1421 living bat species, has generated and analyzed six highly accurate bat genomes that are ten times more complete than any bat genome published to date, in order to uncover bats unique traits.

Given these exquisite bat genomes, we can now better understand how bats tolerate viruses, slow down ageing, and have evolved flight and echolocation. These genomes are the tools needed to identify the genetic solutions evolved in bats that ultimately could be harnessed to alleviate human ageing and disease, Emma Teeling, University College Dublin, Co-Founding Director of Bat1K and Senior Author.

To generate these exquisite bat genomes, the team used the newest technologies of the DRESDEN-concept Genome Center, a shared technology resource in Dresden, to sequence the bats DNA, and generated new methods to assemble these pieces into the correct order and to identify the genes present.

Using the latest DNA sequencing technologies and new computing methods for such data, we have 96 to 99 percent of each bat genome in chromosome level reconstructions an unprecedented quality akin to for example the current human genome reference which is the result of over a decade of intensive finishing efforts. As such, these bat genomes provide a superb foundation for experimentation and evolutionary studies of bats fascinating abilities and physiological properties Eugene Myers, Director of Max Planck Institute of Molecular Cell Biology and Genetics, and the Center for Systems Biology, Dresden, Germany, Senior Author.

Relationship to other mammals

The team compared these bat genomes against 42 other mammals to address the unresolved question of where bats are located within the mammalian tree of life. Using novel phylogenetic methods and comprehensive molecular data sets, the team found the strongest support for bats being most closely related to a group called Ferreuungulata that consists of carnivores (which includes dogs, cats and seals, among other species), pangolins, whales and ungulates (hooved mammals).

To uncover genomic changes that contribute to the unique adaptations found in bats, the team systematically searched for gene differences between bats and other mammals, identifying regions of the genome that have evolved differently in bats and the loss and gain of genes that may drive bats unique traits.

Our genome scans revealed changes in hearing genes that may contribute to echolocation, which bats use to hunt and navigate in complete darkness. Furthermore, we found expansions of anti-viral genes, unique selection on immune genes, and loss of genes involved in inflammation in bats. These changes may contribute to bats exceptional immunity and points to their tolerance of coronaviruses. Michael Hiller, Max Planck Research Group Leader, Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Max Planck Institute for the Physics of Complex Systems, and the Center for Systems Biology, Dresden, Senior Author.

Tolerance against viruses

The team also found evidence that bats ability to tolerate viruses is reflected in their genomes. The exquisite genomes revealed fossilised viruses, evidence of surviving past viral infections, and showed that bat genomes contained a higher diversity than other species providing a genomic record of historical tolerance to viral infection.

Given the quality of the bat genomes the team uniquely identified and experimentally validated several non-coding regulatory regions that may govern bats key evolutionary innovations.

Having such complete genomes allowed us to identify regulatory regions that control gene expression that are unique to bats. Importantly we were able to validate unique bat microRNAs in the lab to show their consequences for gene regulation. In the future we can use these genomes to understand how regulatory regions and epigenomics contributed to the extraordinary adaptations we see in bats, says Sonja Vernes, Co-Founding Director Bat 1K, Max Planck Institute for Psycholinguistics, Nijmegen, Senior Author.

This is just a beginning. The remaining ~1400 living bat species exhibit an incredible diversity in ecology, longevity, sensory perception and immunology, and numerous questions still remain regarding the genomic basis of these spectacular features. Bat1K will answer these questions as more and more exquisite bat genomes are sequenced, further uncovering the genetic basis of bats rare and wonderful superpowers.

SEE ORIGINAL STUDY: https://www.nature.com/articles/s41586-020-2486-3

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The genetic basis of bats superpowers revealed - YubaNet

Research Roundup: Progress on COVID-19 Vaccines and More – BioSpace

Every week there are numerous scientific studies published. Heres a look at some of the more interesting ones.

A Big Week for COVID-19 Vaccine Trials

Three of the most advanced COVID-19 vaccines published data from early and mid-range clinical trials this week. CanSino Biologics, along with Chinas military research unit, reported early data on its Phase II trial for its COVID-19 vaccine, Ad5-nCOV. The results in 508 patients showed antibody and T-cell immune responses. There were no reported serious side effects. The data was published in the journal The Lancet.

With one dose, CanSinos human adenovirus vector-based vaccine elicited receptor-binding and neutralizing antibodies in 508 patients peaking after 28 days, wrote Philipp Rosenbaum, senior infectious diseases analyst at GlobalData. However, in the 52% of study participants that had a high pre-existing immunity to the viral vector, both types of antibodies were only at half the level than in the group with low-pre-existing immunity. A second dose of the vaccine might solve this issue, but on the other hand reduce the number of people who can be vaccinated.

The CanSino vaccine uses a modified common cold virus as a vector to deliver the genetic material. This is a method also being utilized by the University of Oxford and AstraZeneca, which also published their results in The Lancet.

The Oxford-AstraZeneca vaccine stimulated a T-cell response within 14 days and an antibody response within 28 days.

Lead author Andrew Pollard, University of Oxford, UK, said, The new vaccine is a chimpanzee adenovirus viral vector (ChAdOx1) vaccine that expresses the SARS-CoV-2 spike protein. It uses a common cold virus (adenovirus) that infects chimpanzees, which has been weakened so that it cant cause any disease in humans, and is genetically modified to code for the spike protein of the human SARS-CoV-2 virus. This means that when the adenovirus enters vaccinated peoples cells it also delivers the spike protein genetic code. This causes these peoples cells to produce the spike protein, and helps teach the immune system to recognize the SARS-CoV-2 virus.

Last week, Moderna and researchers from the National Institute of Allergy and Infectious Diseases (NIAID) and clinical trial centers published the data in The New England Journal of Medicine from its Phase I trial of mRNA-1273, its mRNA vaccine.

The interim analysis was of a two-dose vaccination schedule given 28 days apart at three different dose levels, 25, 100 and 250 micrograms in 45 healthy adults ranging in age from 18 to 55 years. The data published was on results through Day 57.

These Phase I data demonstrate that vaccination with mRNA-1273 elicits a robust immune response across all dose levels and clearly support the choice of 100 microgram in a prime and boost regimen as the optimal dose for the Phase III study, said Tal Zaks, Modernas chief medical officer. We look forward to beginning our Phase III study of mRNA-1273 this month to demonstrate our vaccines ability to significantly reduce the risk of COVID-19 disease.

The companys Phase II trial of the study, with two cohorts, healthy adults ages 18-55 years and older adults ages 55 years and above, are fully enrolled. That study is a placebo-controlled, dose-confirmation study focusing on patients receiving either a placebo, a 50-microgram or 100-microgram dose.

Pfizer and BioNTech announced preliminary data on July 1 from trials of their vaccines, with similar results.

Naor Bar-Zeev and William Moss, with the International Vaccine Access Center at Johns Hopkins Bloomberg School of Public Health, wrote an accompanying editorial in The Lancet discussing both the University of Oxford/AstraZeneca results, also published in the journal, and the CanSino study.

These trial reports are hugely anticipated. The results of both studies augur well for Phase III trials, where the vaccines must be tested on much larger populations of participants to assess their efficacy and safety. Overall, they wrote, the results of both trials are broadly similar and promising, notwithstanding differences in the vector, in the geographical locations of the populations studies, and the neutralization assays used.

They noted that the importance of the studies looking at associations of age and sex with adverse events and immunogenicity by the Chinese group and longevity of response by the British groups, particularly given the differential burden of severe outcomes in older adults, and the emerging science around differential sex-specific vaccine effects. These COVID-19 vaccine trials are small so inferential caution is warranted, but the explorations are laudable. Ethnic diversity in both these trials was very limited.

They also point out that the safety results seen in the two trials are reassuring. But when things are urgent, we must proceed cautiously. The success of COVID-19 vaccines hinges on community trust in vaccine sciences, which requires comprehensive and transparent evaluation of risk and honest communication of potential harms.

Where are the Antibodies to SARS-CoV-2 in the U.S.?

Researchers with the U.S. Centers for Disease Control and Prevention (CDC) and other investigators evaluated 10 locations across the U.S. for antibodies to COVID-19 from March 23 to May 12, 2020. By testing a cross section of 16,025 residual specimens, they estimated the proportion of people with detectible antibodies to SARS-CoV-2 in 1.0% in the San Francisco Bay area to 6.9% in New York City. They found that there were six to 24 times more infections per site than reported COVID-19 cases. However, most people at those locations likely did not have detectable antibodies to the virus. The collection sites were San Francisco Bay area; Connecticut; south Florida; Louisiana; Minneapolis-St. Paul-St. Cloud metro area in Minnesota; Missouri; New York City metro area; Philadelphia metro area; Utah; and western Washington State. The authors concluded, The estimated number of infections was much greater than the number of reported cases in all sites. The findings may reflect the number of persons who had mild or no illness or who did not seek medical care or undergo testing but who still may have contributed to ongoing virus transmission in the population.

Proteins that Protect Synapses Discovered, Could Help Alzheimers and Schizophrenia

Researchers at the University of Texas Health Science Center at San Antonio discovered a new class of proteins that protect synapses from being destroyed. This has implications for Alzheimers disease and schizophrenia. In mouse models of Alzheimers, they found that by removing complement proteins from the brain protected it from neurodegeneration. Complement is an immune system pathway that calls for macrophages to eat excess synapses during development. They identified proteins that inhibit this function.

University of Utah Researchers ID HIVs Dynamic Structure

Investigators with the University of Utah found that the lattice, a major structural part of the HIV virus, is dynamic. It is made of Gag and GagPol proteins and was thought to be completely static. But their new electron microscopy approach, that didnt involve freezing the viral samples, showed that the lattice was dynamic, moving, which may have implications for new approaches to therapeutics.

Oxytocin May Be Used to Treat Cognitive Diseases like Alzheimers

Researchers at Tokyo University of Science found evidence that oxytocin, a hormone dubbed the love hormone because of its ability to induce feelings of love and well-being, can reverse some of the damage caused by amyloid plaques in an animal model of Alzheimers disease. Alzheimers is associated with two abnormal proteins, amyloid plaques and tau tangles. The research was published in the journal Biochemical and Biophysical Research Communications.

This is the first study in the world that has shown that oxytocin can reverse ABeta-induced impairments in the mouse hippocampus, said Akiyoshi Saitoh from the Tokyo University of Science, who led the research. At present, there are no sufficiently satisfactory drugs to treat dementia, and new therapies with novel mechanisms of action are desired. Our study puts forth the interesting possibility that oxytocin could be a novel therapeutic modality for the treatment of memory loss associated with cognitive disorders such as Alzheimers disease. We expect that our findings will open up a new pathway to the creation of new drugs for the treatment of dementia caused by Alzheimers disease.

Saitoh and his team perfused slices of the mouse hippocampus with Abeta to confirm that Abeta caused the signaling abilities of neurons in the slices to decline. Then, they perfused with oxytocin, noting that the signaling abilities increased. Further experiments concluded that oxytocin bound with oxytocin receptors in the membranes of brain cells.

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Research Roundup: Progress on COVID-19 Vaccines and More - BioSpace

Driving to the Interior: On Susan Barba’s geode – Los Angeles Review of Books – lareviewofbooks

JULY 24, 2020

IN GEODE, SUSAN BARBAS conceit is geological time, and it proves a timely guide. With a pandemic challenging our ability to predict the future, to act with care for strangers bodies, and to prioritize nature, her poems offer immensity / with speed bumps and a macro-view through a micro-lens. Her beguilingly exact poems chisel open interior spaces often unseen in everyday life. As in geodes, much of the richness of our perceptions and yearnings remains hidden, mute until it finds an Emersonian sayer. It takes a highly skilled poet to reveal us to ourselves; geode signals the arrival of one whose angle and anvil of vision is acute and necessary.

Barbas earlier book, Fair Sun (2017), includes her grandfathers testimony from his survival of the Armenian Genocide. While that collection explored historys felt presence, geode provides readers with a compass for the psychological terrain of the current moment and for the ecological and social forces that have catalyzed a health crisis. She situates lifecycles generational and geological, personal and planetary within Earths [b]lue-green grid of constant revolution, prompting us to reconsider the terms of our habitation. Like Elizabeth Bishop, she presents demands for a different world in a book that driv[es] to the interior, albeit of our own country and private lives.

Here we are ticking away, / all of us clocks, Barba acknowledges in The Minutes, but she posits the geode as a rival timepiece, independent of human reference. Shorn from limestone or shale, geodes often fit inside the palm, their plain exteriors disguising crystalline cores. A geode also records the context of its making in the way that a poem scores somatic experience in the sedimentary layers of language. [I]n words and rocks / the order is the meaning, she notes, cuing us to the specificity of her syntax and her poems layering.

Precision and subtle intelligence reward her reader. The poem Practice, for instance, offers a slender homily on how to root, in the earth, rage that comes from witnessing human folly.

Your anger is a scrim,clouding your vision.

You see, you hear,and then you testify, you judge.

Write the necessary elegies,the songs of temporary

fury. Human seasons areas leaves, not oaks.

See what foresthas arisen from the rot.

Allow yourselfto be as generous.

*

Oak, whose girthexceeds my reach

forever I amat your feet,looking up.

The poem switches from second to first person as stern self-advice becomes an ode to the oak. Dwarfing us in size and longevity, species of oak tree can live more than 500 years. This largeness (and largesse) in the natural world provides an example to the narrator. Bidding herself to write the necessary elegies, she tempers anger with metaphor human lives as leaves on long-lived trees, making seasonal departures. We, ourselves, wont be here long.

Depicting how sense perceptions rapidly inform ways we testify and judge, the poem counsels two responses: artistic resistance and the consolation of our relative inconsequence. As the poem shifts, it changes posture. It begins with the speaker looking out at the world of human squabble and concludes by looking up, praising a tree whose width surpasses her grasp.

Barbas poems reliably render the problematics of time, systems of care, and human responsibility on a comprehensive scale, venturing in unexpected directions. The early poem Exhibit 2 considers the psychology of habitation. What does it mean to dwell? What kind of living happens in the living room? What does our typical mode of shelter its prevalence of walls and doors invite or inhibit? She poses an answer in 10 compressed lines.

The centrifugal force of a room:four walls, a ceiling.Nothing can get inbut what you admit.Part dark harbor,part isolation chamber.A man whod lived out of doorssaid what hed missed mostwas not a roof, not a lock,but a doorknob.

In a single stanza, which means room in Italian, the walls and ceiling appear to flee from the center. The dweller, meanwhile, exerts agency in choosing what to admit, perhaps in both senses allowing entry or confessing. Privacy, fetishized in American culture and most often celebrated in its violation, seemingly protects us from vulnerability: what we do not wish to admit, whether guest or secret. In its spare exactness, the poem underscores the tension between isolation chamber and dark harbor, or loneliness versus chosen solitude. Thus the concluding meditation from a man who has lived not outdoors but, more concretely, out of doors suggests that the doorknob signifies having a choice in how we negotiate self and other, how we demarcate interiority in physical space.

Poems in geode also explore the crystalline webs between parent and child, lover and beloved, self and commodity: dyads with socially reinforced centripetal pull. Barba tracks individuation within these relationships and a primal desire for self-possession. As a daughter ventures into ocean surf, her dark head of hair bobs, visibly, as if she were performing a captioned ballet: ballon after ballon / this is my life! The childs postural repudiation of parental care is recast as a secular blessing in the poem Retrospective, Agnes Martin, which addresses the expressionist painter known for her years of disciplined solitude in the New Mexican desert. That poem concludes: if I could give you one thing / it would be untitled space. Autonomy is the essential assertion of children and artists, alike.

Similarly, the speaker in Wide Margin Love Poem bids for a Rilke-esque notion of love as the protection (rather than the collapse) of identity in a narrow column that threads the middle of the page.

Let melet yoube asbeforeor asafterme.

Wise about the claims individuals make on each other, even in love, the poet also contests the demands of commerce. In Blank Placard Dance, a poem about a protest dance performed in 1967 by Anna Halprin, the speaker urges her addressee to retain your stony / surface, stony structure. / Defend the palimpsest / that is your face. Expressivity, or the ability of the face to compose an array of changing affects, is what anonymizing data collection, targeted marketing, Botox, and stealth technology seeks to minimize or eliminate.

While geode features keenly cut lyrics, economic to the syllable, that elucidate murky interiors of what remains of private life, Barba also showcases her sophistication in other modes. In the epic poem River, she extends her concern for the tenets of personhood to the Colorado River, reinforcing her primary argument that we privilege human life and extractive capitalism over the earths health at our peril. The 12-page poem recounts the legal case The Colorado River Ecosystem v. The State of Colorado, which would have granted the river legal standing of personhood and rights akin to other ecosystems such as the Ganges River in India. The poem maps the rivers magnitude, extending 14 million acre-feet from the Rocky Mountains to the Pacific Ocean, supplying arterial lifeblood to nearly 40 million human beings, four million acres of cropland, and countless creatures. An epic catalog of the watersheds species includes the humpback chub and peregrine falcon, the bonytail and black bear, a list she punctuates with the poignant refrain, stay with me now.

Naming these dependent species underscores that the river is a person on whom an ecosystem, a nation of life, depends. Yet the case was dismissed in 2017 by the United States District Court for the District of Colorado, leading Barba to ask one of the books searing questions:

Is it by virtue of this immense life-giving laborthat the river is not a rights-holderbut a natural object,meant for profit,like slaves like womenan order apartlike the roe and the deer?

Misuse of the Colorado River is situated as part of a broader pathology of patriarchal capitalism, which refuses to acknowledge its instrumentalized objects as subjects. This section of the poem concludes with a riveting quotation from a 1968 casebook in property law: [A]fter all, land, like woman, was meant to be possessed.

The legal suit for the Colorado River epitomizes claims we might wish to make within our own lives against the exploitation of our labor, privacy, or attention. In the poem Dispersal, the narrator recounts making a long commute where she feels the light slip / the more she strove. Grappling with global news, her neighbors razed forest, and needy children in the backseat, she composes a petition:

re. space she wantednothing morethan a marginundisturbed

re. time she wantednever to accept it

the trees succumbingto storms with proper names

the grass succumbingto polypropylene

[]

she and I and youand they and he

seeds

seekingmore than a lifein the wind.

Susan Barba dramatizes ordinary life, riven with obligation, and a yearning for time, space, and an identity untethered to others claims. Her aesthetic marries the elliptical startle of Lorine Niedecker and Robert Creeley to the documentary impulse of Muriel Rukeyser and Charles Reznikoff, advocating for a comity with the earth and with our fragmented selves that is both visionary and diagnostic. We cannot have permanence or limitless abundance. But geode asserts that we might still claim purpose in our time on this spherical spinning rock.

Heather TreselersParturition(2020) won Irelands Munster Literature Centresinternational chapbook prize. Her poems appear inThe Cincinnati Review,Harvard Review,Alaska Quarterly Review,Southern Humanities Review, andThe Iowa Review,among other journals.

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Diana Raab Healing Thousands via Memoir Writing and Therapeutic Writing on DailyOM – Press Release – Digital Journal

Loving Healing Press (LHP) publishes work that promotes self-healing, liberation and empowerment. By writing empowering and helpful books, many of its authors make a difference in the lives of readers.

Diana Raab (MFA, PhD) is a prominent LHP author who has inspired and motivated thousands and thousands of readers and writers via her writings, poetry and workshops. She is an award-winning writer and practical educator who helps her audience by teaching memoir writing and writing as therapy. She teaches two courses on DailyOM, Write. Heal. Transform: A Magical Memoir Writing Course and Therapeutic Writing, which are the sites top two writing courses. In recent months, Raabs online course in memoir writing has been ranked #1 of all DailyOM courses.

More than 12,000 people have enrolled in Raabs online courses. Write Heal Transform. As the course title implies, it serves as a hands-on guide to healing and transformation through writing ones own memoir. The eight-week course consists of eight lessons (one lesson per week) that teach the basics of memoir writing and the ways in which this type of writing cultivates self-awareness and using ones voice to speak ones truth. In short, Diana Raabs course helps wounded healers become storytellers. Her new course, Therapeutic Writing, is an empowering ten-day course guiding and supporting participants in using writing as a therapeutic tool to individual self-exploration.

A unique feature of DailyOM courses is that the price is not fixed, and those interested in taking them can pay what they can afford, starting from as low as $15 up to $50; the same material is available to those taking the course - regardless of what payment option they choose. The course page reads:

We simply trust that people are honest and will support the author of the course with whatever they can afford. And if you are not 100% satisfied, we will refund your money.

When asked about the most important takeaways from her courses, Raab said, There are a few salient points that I emphasize in all my workshops, whether its memoir writing or writing for healing, and whether its an in-person or an online course. First, writing is a process. Second, its important to enjoy the process or journey without focusing on the destination (possible publication), because this can detract from the creative aspect. Third, its important to write without fear. Writing our personal stories can be scary and daunting. Its important to drop the fear and just write. As my first writing mentor told me, Let it rip.

Readers can learn more about Diana Raab and her work via http://www.dianaraab.com.

Media ContactCompany Name: Diana Raab, PhDContact Person: Media RelationsEmail: Send EmailCity: Santa BarbaraState: CaliforniaCountry: United StatesWebsite: https://dianaraab.com/

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Diana Raab Healing Thousands via Memoir Writing and Therapeutic Writing on DailyOM - Press Release - Digital Journal

How, and Where, Covid-19 Is Spreading in Africa – Direct Relief

Africa currently has the second-fewest number of confirmed Covid-19 cases in the world, except for the World Health Organizations Western Pacific region, according to the most recent WHO figures. In total WHO Africa member states have 623,851 confirmed cases, including 12,666 in the past 24 hours. More than half of these cases are in South Africa. Across the continent, at least 10,116 have died from Covid-19.

However, African nations also have some of the lowest rates of testing in the world, with Nigeria offering one test daily per 100,000 people (18.44% positive), Ghana at 10 tests daily per 100,000 (10% positive) and South Africa at 26 tests daily per 100,000 (7.25% positive). For comparison, the U.S. offers 168 tests daily per 100,000, with 6.51% coming up positive, according to data sourced by Johns Hopkins University.

Assessing the full scope of the situation among its member states, Dr. Miriam Nanyunja, regional advisor for emergency risk management for WHO Africa, said the pandemic has not spread to all countries within Africa in the same way. In Mauritius, six recent were all imported in Seychelles, local transmission ended in April.

She pointed out that 88% of confirmed cases are in 10 countries, led by South Africa, and also including Nigeria, Ghana, Algeria, Cameroon, Cte dIvoire, Kenya, Ethiopia, Senegal, and the Democratic Republic of the Congo. Egypt, which has over 89,000 cases, is not part of WHOs Africa region. Sixty percent of cases are in people under 60 years old, and the average age of people with confirmed cases of Covid-19 is 38 years old, according to WHO figures.

Community transmission is present in about 70% of WHO Africa countries, but the Nairobi-based Nanyunja said its not nationwide in any situation, even as overall rates of increase are problematic.

It took Africa 100 days to reach 100,000 cases, but then only 18 days to double to 200,000. It took 20 days from there to 400,000 and now we are at over 620,000. We see the increase and we are not happy about it, she said. Addressing the testing issue, she said capacity is increasing without a correlated increase in cases.

What we see is that, even with increasing testing, the cases do not rise so significantly, she said. What we are seeing is more of a good proxy of what is on the ground.

Direct Reliefs Research and Analysis team has been tracking vulnerability in the region based on case counts per capita, number of hospital beds, HIV case counts, food insecurity, population over 60 years old, and other factors. This month, Mali, Mauritania, Benin, Chad, and Tunisia have reduced their vulnerability while Lesotho, Namibia, Congo, Swaziland, Zambia, Madagascar, and South Africas vulnerabilities have increased.

Nanyunja said many member states, especially in West and Central Africa, have been able to incorporate principles from the 2014 Ebola outbreak, even as Covid-19 presents unique challenges.

Ebola outbreaks have taught us one big lesson about the importance of communication in effective response: Build trust in the local community. We have to include cultural sensitivity in the response. We have to communicate why we are proposing a change in their social norms, otherwise, they will not listen much.

During the Ebola outbreak, WHO used anthropologists and social workers in order to tailor their advice to local communities. Survivors of the disease also provided to be effective mobilizers for response initiatives, she said.

Social distancing and masks have not been a social norm, so we have to engage communities to adjust. In general, we are seeing countries that faced Ebola putting into good consideration all these factors.

Amongst member states, unlike in the U.S., there has not been widespread resistance to the advice of public health officials, but, We are seeing increasingly a level of fatigue and complacency resulting in apathy in the implementation of the interventions, Nanyunja said.

Initially, the countries took on prevention measures and there was goodwill in the population and they tried their best in social distancing, staying home, and with restrictions on travel. In some circles, there was inadequacy in completing this, more to do with socioeconomic reasons: staying at home was affecting livelihoods. And segments of the population would not comply due to these challenges, she said.

She said another challenge has been the inconsistent use of masks in several countries, due to misconceptions, including that masks hinder breathing.

Looking at the U.S., Nanyunja said she was surprised by the response.

We all believed the public health system in the U.S. could mount a response that could control the pandemic, like in China, or even faster, but things have turned out different.

She thinks applying some of the Ebola lessons will help matters in the U.S. as well.

What would be good is for the U.S. is to adopt strategies to the local context. The principles remain, but it is adapted to the context to the different states in the U.S. and then also using local data to guide the implementation see which areas are most affected and implement the strategies in those areas.

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How, and Where, Covid-19 Is Spreading in Africa - Direct Relief

Spacecraft Launched by NASA, ESA Sends Back the Closest-ever Images of the Sun – WFSB

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Spacecraft Launched by NASA, ESA Sends Back the Closest-ever Images of the Sun - WFSB

The flawed brilliance of J.B.S. Haldane – The Economist

Jul 18th 2020

A Dominant Character: The Radical Science and Restless Politics of J.B.S. Haldane. By Samanth Subramanian. W.W. Norton; 400 pages; $40. Atlantic Books; 20.

TOWARDS THE end of his life, J.B.S. Haldane was inseparable from a pebble that had been found in the Valley of Elah in Israel, where David felled Goliath with a similar projectile. A king-size man who towered over British biology for several decades in the middle of the 20th century, Jack Haldanethe half-Danewas a more obvious Goliath, but he always took the side of the underdog.

That is the contradiction at the heart of Samanth Subramanians astute and sympathetic biography. An Eton- and Oxford-educated communist, who with a handful of others fleshed out Darwins theory of natural selection by marrying it to genetics and grounding it in maths, Haldane was born into privilege but came to identify himself with the masses. And if his unconscious sense of entitlement can sometimes be grating, it is more than offset by his humour, facility for language, intellectual generosity andthe product of all thishis giant contribution to the popularisation of science.

Science was his first and most enduring love. Aged three, studying blood trickling from a cut, he is supposed to have asked, Is it oxyhaemoglobin or carboxyhaemoglobin? Thus began a life of inquiry in which he was always either being experimented onnotably by his father, the physiologist J.S. Haldaneor experimenting on himself or others. Bertrand Russell thought that science could rarely be beautiful, but for Haldane beauty came through understanding. Until I took to scientific plant-breeding, he wrote, I did not appreciate the beauty of flowers.

Haldane wrote a great deal, in learned journals but also in the popular press and in response to letters from the scientifically curious, and on a breathtaking range of subjects. Please send me no more caterpillars, he pleaded on one of the many occasions that his mailbag threatened to overwhelm him. As he coped with his own and other peoples inquisitiveness, world events intruded. He wrote parts of a paper on genetic linkagewhereby two genes that sit close to each other on a chromosome are more likely to be inherited togetherwhile serving in the trenches during the first world war.

It was in the trenches, too, that Haldanes rejection of his birthright crystallised. As disappointed by the officer class as he was by army chaplains, he wrote to his mother that, when the revolution came, the people would strangle the last Duke in the guts of the last parson. But he was attracted to Marxism for more than just its egalitarian ideals; it struck him as practical, transparentin short, scientific. Though he kept his distance from the Communist Party of Great Britain (CPGB) until 1942, MI5 had him down as a subversive from the time of his only visit to the Soviet Union, in 1928.

Haldanes politics and his science clashed mightily in 1948, when as the CPGBs foremost intellectualand, by then, one of the most influential geneticists in the worldhe refused to publicly condemn the pseudoscience of Trofim Lysenko. Stalins favourite agronomist claimed that he could drum desirable traits into wheat by altering its environment, just as Jean-Baptiste Lamarck had once believed giraffes had stretched their necks through practice. In the Soviet Union scientists who disagreed with Lysenko vanished. One of them, Nikolai Vavilov, had hosted Haldane in Moscow. Haldanes own science contradicted Lysenkoism. Nobody who knew him could fathom his stance.

Mr Subramanian doesnt defend it either. He makes it clear that Haldane ignored overwhelming evidence of Vavilovs internment and death in the gulag. But he uses the episode to illustrate a wider truth, which is that science cannot be extricated from politics. Today many scientists describe their research as apolitical, but Haldane knew that was impossible: I began to realise that even if the professors leave politics alone, politics wont leave the professors alone.

It meant that he was prepared to change his mind. Eugenics was a mainstream theory when he entered biology, and he partially embraced it. But he also warned that genetics was too young a science to be applied successfully. His ideas evolved until they fell into line with those of the scientists now wielding genetic-engineering tools to improve humanity (though they would reject the eugenics label).

Haldane changed his mind too slowly about the Soviet Union, but having done so he found new hope in India, where he moved in 1957. Its bureaucracy maddened him and he said so loudly and oftenflashing his white male privilege like a peacocks tailbut its tropical profusion provided him with a natural laboratory, and the climate was kinder to a body damaged by decades of self-experiment. When he died there in 1964, still holding the stone from Elah, it was no surprise to anyone that he donated his body to science.

This article appeared in the Books & arts section of the print edition under the headline "Trial and error"

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The flawed brilliance of J.B.S. Haldane - The Economist

Vegetarian Bachelorette Ali Fedotowsky on What She Eats in a Day – The Beet

America first fell in love with outspokenAli Fedotowsky-Manno on the reality TV showThe Bachelor, andcan never forget the moment when she walked out onJake Pavelka, quitting the show to "focus on her career." Thereality star favorite was chosen to return as"The Bachelorette," in 2010 when 25 bachelorscompeted for her love. Since then, Ali broke ties with the show completely and married Kevin Manno in 2017 and had two children with the TV host, Molly, and Riley.

The joyful and bubbly blonde prioritizes the things she loves: Family, vegetarian food, and being a hardworking mother,developing her career around her passion for a mostly plant-based lifestyle. Fedotowsky, who calls herself a vegetarian, only showcases plant-based products on her social channels from what we can see. She is the founderAli Manno, where she presents a stress-free and lightheartedapproachfor mothers, plant-based eaters, and the contemporary chic fashion-lover.

In a sad turn of events for Ali, which she shared this week, she recently lost a pregnancy to miscarriage and she wanted to share this with her fans so that it would not be something women feel they have to be secretive about if it were to happen to them. She is ever supportive of other women, andher heartbreaking IG post about it is another example of that.

Ali has been a vegetarian for 8 years andstarted the diet "on a whim," she tells Women's Health. "A friend suggested I try pescatarian. I thought I'd do it for like two weeks, and then here I am eight years later. I've never gone back."

On her blog, Ali shares delicious recipes and does not hold back from indulging in carbs. She loves pasta and bread--as do her children. In the photo below, Ali makes a sweet and savory snack, Crostini with California Walnuts with her oldest daughter Molly, and emphasizes the health benefits of walnuts and the importance ofgetting your dose of Omega 3's. All of her recipes are 100% children-approved and she inspires moms everywhere to try to feed their kid whole foods since she posts pictures of her kids loving healthy plant-based snacks!

Ali is no stranger to the meat-free diet but she still enjoys her treats, she says, and the point is not to deprive yourself. Her approach appears to be working: She eats what she enjoys and she feels and looks amazing. In the interview with Women's Health Magazine. Ali says swearing off meat has worked for her body and eliminated a lot of her junk food cravings. "I eat when I'm hungry and I don't deprive myself," she says. "If I want something, I've let myself have it. I think it's important to enjoy food and to focus on having a healthy lifestyle instead of dieting."

Hertrick to balancing being a busy mom, a CEO, and a wife: Ali likes to make convenient food healthy, which means that for lunch she will create a big veggie platter and eat it all afternoon. Or she will make a clean pasta without loading it up with meat sauce. Ali was asked in the interview what she typically eats in a day, which is mostly plant-based food that you can make too.

Starting with breakfast: Molly and Riley will eat a PB & J with Walnut Butter and notesthat she loves Crazy Go Nuts Walnut Butter. Ali admits she works out hard in the morning, saying, "People joke that I should have been a professional athlete because I'm a crazy person when I work out." After a big sweat and lots of calories burned, Ali said: "I crave pasta in the morning and people think that's insane, but I've been eating pasta for breakfast since high school." She eats a bowl of pasta on some mornings but other times she will enjoy a big bowl of broccoli and edamame with her favoriteWalnut Parmesan Cream. "It doesn't actually have any cream in it but is the best recipe ever. I literally make it every day," she told Women's Health.

Next, a light lunch for a busy mom: As seen on Ali's blog, she likes to keep lunch light. Her favorites are mini potato skins topped with fresh guacamole, and a healthy farro bowl made with fresh vegetables and can simply be made vegan without the added parmesan cheese.

It's healthy snack time:Ali's snack when she's on the go is an apple-pie Lrabar that's made with 6 ingredients: Dates, almonds, green apples, walnuts, raisins, and cinnamon. She says she tends to stick to more healthy convenient snacks. "I love to buy veggie trays and leave them on the counter so we can come up and grab the veggies throughout the day."

Dinner is served: Ali likes to serve healthy dinners that include complex carbs and plant-based proteins. She told the magazine thatshe "whips up all sorts of plant-based combos using ingredients like quinoa and black beansand plenty of green veggies. Vegetarian "chicken" nuggets also make regular appearances on the kiddos' plates." In addition, she adds, "Of course, pasta is also a staple at dinnertime."

Dessert is simple:Ali said she loves to relax once the kids are in bed and sip an organic wine, andindulge inchocolate chip cookies. "ThoseTate's Chocolate Chip Cookiesare so stinking good. I just have one of those and drink my wine, and it isheaven." Tates cookies are vegetarian, but sadly., because they contain eggs and butter,arenot yet vegan. So if you're looking for a delicious store-bought cookie brand that is completely vegan, check out The Beet's favorites here.

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Vegetarian Bachelorette Ali Fedotowsky on What She Eats in a Day - The Beet

This Premier Protein Coffee Drink is Trending on TikTok, But Is It Healthy? – Parade

Among the many things people miss when they start following a keto diet, coffee creamer is often one of them. Most coffee creamers are keto diet no-nos because they have too much sugar and carbs to qualify as a keto-friendly food. But we can all agree that coffee tastes amazing with a dash of sweet, creamy goodness, right?

Many keto dieters switch from traditional creamers to beefed up, healthier versions that contain super ingredients like MCT oil, coconut oil and almond milk. These can help promote weight loss and provide a healthy energy boost. But if youre a keto-friendly coffee lover, theres a new trend in town: Adding a dash of Premier Protein to coffee for a boost of protein to your morning brew. The idea is that youre able to add something tasty to your coffee all while staying full longer and getting a caffeine boost.

We know the Premier Protein trend is a popular one, but is it healthy? We took a closer look at the ingredients and spoke to an expert to find outheres everything you need to know.

Premier Protein is a packaged protein drink that contains 30 grams of protein in a single serving. But with only five grams of carbs per serving, its keto-friendly. Its marketed in much the same way as competing protein drinks: for use as a meal replacement, as part of a healthy diet for weight loss, or for someone who struggles to take in enough calories and is looking to gain weight.

Premier Protein comes in six flavors: Chocolate, vanilla, caramel, cafe latte, banana and strawberry, and is widely available everywhere from pharmacies and grocery stores to Costco and Amazon.

Related: What Is The Keto Diet and How Does it Work?

Lunch is served !!! #keto #premierprotein #bomb #coffee

original sound katelynnekate

The endless enthusiastic videos of people doctoring up their coffee with Premier Protein make it looks like cant-miss coffee additionbut is adding Premier Protein to your coffee really a good idea? The answer depends on what youre using it for. In general, adding protein to your first drink or meal can lead to suppressing the appetite and a perception of an energy boost. This can lead to a lower caloric intake and subsequently weight loss or leaning in the body-building process, says Niraj Shah, a BJC Medical Group board-certified physician in family practice, obesity medicine and lifestyle medicine.

So if youre looking for a tasty coffee creamer that will keep you in ketogenesis, Premier Protein is a solid addition to your morning coffee.

Related: Keto Kitchen Makeover

But what about from a long-term health perspective? Can Premier Protein fit into a balanced diet thats part of an overall healthy lifestyle, or is it simply just another weight loss hack? According to Shah, using protein to suppress appetite will yield results if youre focused on weight loss. However, research has shown that this type of approach produces only short-term results.

In a lot of ways, the Premier Protein trend may be a bit of a quick fix. So if you do hop on board with it, keep in mind that a healthy lifestyle also includes a well-rounded diet and plenty of exercisePremier Protein coffee isnt a magic bullet.

Related: Keto Diet Food List

Wondering how you can incorporate Premier Protein into your morning cup of coffee? The way you go about it depends on your personal preferences, but here are some simple ways to make your own Premier Protein coffee.

Celebrity interviews, recipes and health tips delivered to yourinbox.

Theres no question that the Premier Protein coffee trend is a popular one, and it can be healthy if used in the right way, especially if youre following the keto diet. Happy sipping!

Next, try one of these 14 low-carb keto smoothies, shakes, and cappuccinos.

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This Premier Protein Coffee Drink is Trending on TikTok, But Is It Healthy? - Parade

Heart disease: Is red wine good for your heart? The amount you should drink – Express

Heart disease is a phrase that refers to various types of conditions that affect heart function. This includes coronary heart disease, valvular heart disease, heart rhythm disturbances, coronary artery disease and more.

Red wine contains antioxidants that might help to prevent coronary artery disease, a type of heart disease that leads to heart attacks.

However, as the British Heart Foundation site points out, fruits such as grapes, blueberries, and strawberries also contain antioxidants.

Plenty of healthy veggies such as kale, spinach, and artichokes are packed with antioxidants.

Swapping to a healthy diet full of fruits, vegetables, beans, and pulses is a better option than drinking red wine every day.

READ MORE- Best supplements for the heart - how to protect against heart disease

In fact, drinking red wine can actually lead to heart disease rather than prevent it.

Alcohol, including red wine, is a depressant drug and slows down your brains control of your body.

It affects important functions such as speech and movement, and can slow your heart rate and breathing down to a dangerously low level.

Drinking too much alcohol on a regular basis can seriously damage your heart, so dont use the antioxidant content of red wine as an excuse to binge drink!

BHFs site also points out the link between alcohol and high blood pressure.

Over time, high blood pressure puts a strain on your heart and can lead to cardiovascular disease.

Cardiovascular disease is one of the main causes of death and disability in the UK, but it is easily prevented by leading a healthy lifestyle.

Other habits and traits that put you at risk of heart disease include smoking, diabetes, high cholesterol, lack of exercise, and your ethnic background.

The pressure on your heart also increases your risk of heart attack and stroke.

There is no evidence to sufficiently support your decision to start drinking red wine regularly in order to avoid heart disease.

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If you drink most weeks, the NHS advises you to drink no more than a specific amount to keep health risks to a low level.

Both men and women are advised to drink no more than 14 units a week on a regular basis.

Thats about ten small glasses of low-strength wine, or six pints of average-strength peer.

If youre trying to cut down, you should try to have several drink-free days a week.

The NHS also points out that there is no safe drinking level, and thats why drinking less than 14 units a week is called low risk drinking rather than safe drinking.

Alcohol can not only cause heart disease, but it can also lead to cancers of the mouth, throat and breast, stroke, liver disease, brain damage, and damage to the nervous system.

The risks of drinking alcohol regularly outweigh any possible benefits you may have heard of.

The only group of people who might see some benefit overall in the UK is women over the age of 55.

However, there isnt enough evidence to say this is definitely true and it only applies to low levels of drinking - around five units a week or less.

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Heart disease: Is red wine good for your heart? The amount you should drink - Express

Here’s how we’re deciding where to travel this summer – Business Insider – Business Insider

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If you asked me a few months ago where I'd travel this summer, I would have answered easily: Greece, to reschedule my spring trip that was canceled due to the pandemic. Or, as a domestic back up, I was ready to compromise on Hawaii. Big of me, right?

Now, of course, I see the naivety and hopefulness in thinking normalcy would return so soon.

Sadly, the novel coronavirus continues to hit the US with record force. As a result, I, along with many others, have spent months sheltering in place, practicing social distancing, and wondering if it will be safe to travel this summer, or anytime soon.

But with summer in full swing, even the most vigilant are feeling the effects of cabin fever. Many are choosing to travel locally where infection rates are slowing, with key modifications in place to foster health and safety.

For example, I may cover travel for a living, but I'm not yet comfortable entering an airport or booking a crowded resort. Instead, I plan to drive to Cape Cod and stay in a cottage with a private entrance that closely follows COVID policies.

And I'm not alone. My colleagues at Insider Reviews are also considering safer vacation alternatives to traditional travel during COVID, from navigating road trips to trading hotels for campsites. These might not be the places we originally planned to visit, but we've discovered a few gems on the way, and there's no compromise on quality.

However, it's important to remember that what feels comfortable to one of us might not be right for you. It's crucial to assess your own risk and understand that without a vaccine, it's impossible to guarantee safety. Also, consider whether you're leaving or traveling to a hotspot, so as not to contribute to infection spikes. And follow guidelines from the CDC and WHO such as wearing a mask, washing your hands, and social distancing, no matter where you go.

Still, it's summer, and that conjures images of precious PTO reserved for sunkissed vacations and sacred time with loved ones exploring new places or returning to nostalgic favorites.

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Here's how we're deciding where to travel this summer - Business Insider - Business Insider

The Best VPNs of 2020 – Reviewed

How We TestedThe Tester

My name is Holly Aguirre. I have years of experience torture-testing hardware peripherals at the PC Magazine labs, as well as all things home office, including cyber security. As of late, Ive been covering the ongoing Jeffrey Epstein saga for Vanity Fair and Lifetime Networks, and consequently found myself in need of a reliable VPN. One good hacking will do that to you.

A good VPN has a number of elements, some of which we considered essential and some we considered as nice-to-haves. Data security is, of course, the chief priority. Its also the most difficult to verify in any absolute sense. While we established some minimum requirements for consideration to our list256-bit encryption, kill switches, and compatability with Windows, Mac OS, Android, iOS, and Linuxtheres no getting around the fact that your data has to pass through servers somewhere in the world that you dont have control over. Theres a certain amount of trust involved.

We, therefore, looked for VPN services that are based in countries with strong privacy laws, that make commitments to transparency, and that allow 3rd-party audits to verify their security.

Secondly, we considered the various use cases for a VPN and created tests to evaluate them. VPNs with more features, like geo blocking and more servers went to the head of the class, even if they were more expensive.

Speed was another vital ingredient in a good VPN. Faster connections prove valuable for gaming, torrenting, streaming and much more. We used download, upload, and ping times to gauge speed, but with the full understanding that any number of other factors, such as location, time of day, and network capacity, can impact the speed in your home. For a better understanding of other people's experiences with the VPNs we tested, we looked to reviews from sites such as PCMag, Toms Guide, and CNet.

Finally, we took a hard look at customer service, payment options, cancellation policy, the number of devices allowed per account, ease of use, the number and location of servers, and other factors.

Each VPN was installed and tested on five or more devices: a blend of Windows and Mac OS, including laptops, iPads, and smartphones.

VPNs, while simple to use, can be fairly technical to explain. Here's some useful terminology:

In addition to safe surfing, there are myriad reasons to use a VPN. Due to the global pandemic, telecommuting is a new reality for many office workers, and earlier this year IT departments were left scrambling to provide workers remote security solutions they once controlled in-house. Any one of the VPNs featured here is an easy fix to some of the more common data privacy issues. And in turn, a personal VPN can hide your online activity from your boss.

Additionally, you might use a VPN to stream geo-blocked content or improve online speeds.

Credit: Reviewed / Jackson Ruckar

Our winner, ExpressVPN, won us over with its ease of use, reliability, and commitment to privacy.

Netflix and BBC iPlayer are just two streaming services in which your global location determines the content that you can see. Since a VPN spoofs your location, the right one can also unlock a whole new world of shows and news.

Perhaps youve settled in for movie night only to have Jason Bateman freeze in mid-sentence over and over. This may be happening because your ISP is allowed to throttle your connection speed whenever it likes, probably when everyone else is getting comfy, too. Connecting to a server via a VPN in a different time zone may increase your home internet speeds for content viewing and gaming alike.

Lastly, your web surfing habits, ad clicking and/or purchasing history could make you the victim of price gouging. Some shopping sites charge based on geographic location, perhaps to offset free shipping. Utilizing a good VPNwhile it takes more timecould potentially save you a lot of money on travel and other goods and services.

While there are free VPN options from a handful of reputable companies, this is one category where a little money goes a long way. The free options tend to be very slow or severely limited in the number of options they offer. And as youre not a paying customer, youre also subject to the very ads that youre trying to avoid being tracked by. The one exception here is TunnelBear, which offers a free and robustly-featured version of its VPN capped at 500MB per month.

We use standardized and scientific testing methods to scrutinize every product and provide you with objectively accurate results. If youve found different results in your own research, email us and well compare notes. If it looks substantial, well gladly re-test a product to try and reproduce these results. After all, peer reviews are a critical part of any scientific process.

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The Best VPNs of 2020 - Reviewed