Albright College Fashion and Chemistry Faculty Connect to Make Fabric Face Masks – bctv.org

Posted on April 14, 2020 by Danzig

Days after beginning to work remotely in mid-March, Albright Associate Professor of TheatreandFashionand Costume Shop Coordinator,Paula Trimpey, M.F.A., heard that supplies for nurses were already in critical supply. So she fired up her sewing machine and began making face masks for anyone who asked. Associate Professor ofChemistry and Biochemistry,Christian S. Hamann, Ph.D., took up the charge of sterilizing the masks.

It started with a theatre alumnus who wanted some for a family member with a compromised immune system and went on to many,many friends and family members, said Trimpey. So far, the masks have gone to a Doctor of Pharmacology at John Hopkins in Baltimore, a nurse at theReading Dialysis Unit,Albright College Public Safety and Aramark Food Services at Albright, said Trimpey.

We use 100% cotton with a high thread count since this also bleaches well. The ties allow for any size face/head where elastic masks can sag on small faces/heads.

On April 3, Governor Tom Wolfcalled for all Pennsylvanians to wear maskswhen venturing away from home, but to reserve surgical and medical mask for health care workers and first responders.

Masks help prevent people from sharing illnesses, said Wolf. But, they dont do a great job at keeping people from getting sick; and, theyre not foolproof, so it is critical that our first act is to ask ourselves if we really need to leave our house. If we dont really, truly need to leave, then we shouldnt.

To help others create homemade masks, Trimpey and Hamann created a series offive how-to videos, showing the full process, from cutting patterns to sterilizing finished masks.

>Watch videos

JMU Chemistry department uses chemicals left in the building to make hand sanitizer – WHSV

Posted on April 14, 2020 by Danzig

HARRISONBURG, Va. (WHSV) With labs shut down until further notice amid the COVID-19 pandemic, James Madison University's Chemistry Department is using some of the chemicals normally meant for teaching to aid local medical workers instead.

According to a statement from JMU, heads of the department quickly realized that some of their stored chemicals, like ethanol, glycerol and hydrogen peroxide, could be combined to make hand sanitizer, which has been in short supply in the Shenandoah Valley, just like most of the country.

"When I saw that hand sanitizer was needed, I asked our stockroom manager, Brian Kane, to do an inventory of the departmental supplies that we would need to make the sanitizer according to the WHO recipe and to calculate how much we could make with our unused chemicals," said Linette Watkins, unit head for the JMU Chemistry Department.

According to the school, Kane determined they had enough chemicals on hand to make about 100 liters, but could make around double that amount if they could find more glycerol.

"When the department faculty found out that we needed glycerol to make more, they donated more glycerol from their own labs to increase our capacity and we hope to make at least 200 liters," Watkins said.

The supplies are being pulled from the inventory by Kane, who is also making labels and then leaving them for Chakree Tanjaroon, an instrument chemist, who is making and bottling the solutions, according to Watkins.

Tanjaroon, who also is in charge of checking the building and helping keep equipment safe while the department lowers its energy expenditures, has been working alone to abide by social distancing protocols and has been making 30 liters a day.

The department donated its first 50 liters last week to Augusta Health.

Watkins said sanitizer will also be made for Sentara Rockingham Memorial Hospital and local doctors offices. Students may be employed to make some no-contact deliveries in the next few weeks.

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JMU Chemistry department uses chemicals left in the building to make hand sanitizer - WHSV

Is there a My Chemical Romance nod in this twenty one pilots video? – Alternative Press

Posted on April 14, 2020 by Danzig

With the country on virtual lockdown, many people have turned toward iconic bands such as twenty one pilots and emo royalty My Chemical Romance for entertainment during the coronavirus pandemic. Some have spent their time rewatching videos and noticing Easter eggs from the bands for the first time.

One twenty one pilots fan uncovered a potential nod to MCR in the video for their Trench song, My Blood.

The duo have long been fans of My Chemical Romance. In 2017, they covered the MCR song Cancer for a tribute compilation album celebrating the tenth anniversary of My Chemical Romances The Black Parade.

The band even added the cover of Cancer to their live show setlist. In 2017, they played the song throughout the Emotional Roadshow tour.

twenty one pilots take on the song was celebrated by both fans and MCR frontman, Gerard Way.

It was great. I was really impressed. I didnt know what to expect, and I was surprised by what I heard, Way shared. He added that he was a fan of the band and that what they do is really interesting.

Now, a Reddit user posted a screenshot of the My Blood video suggesting that twenty one pilots MCR tribute doesnt stop with their cover.

Focusing on the Halloween party the band performs at in the video, the user points out a person is dressed up in a black bandleader hat with silver accents. Theyre also wearing a spiked collar and have an exaggerated painted black smile. All of this is reminiscent of My Chemical Romances iconic The Black Parade era from the skeleton named Pepe dressed in a bandleader costume to the bands own attire.

The screenshot got a couple of comments, with one person saying that it was interesting seeing a nod to My Chemical Romances magnum opus in another bands video.

Someone else said it wasnt surprising given that twenty one pilots are huge fans of My Chemical Romance. Given how deep twenty one pilots go with their own imagery, we cant help but wonder if there are other hidden references to MCR or otherwise in their other videos. You can take a look at the costume for yourself at 2:05.

Do you think the outfit was a nod to The Black Parade or not? Let us know in the comments below.

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Is there a My Chemical Romance nod in this twenty one pilots video? - Alternative Press

What Exactly Is an At Home Chemical Peel, And Which One Is Right for Me? – Yahoo Lifestyle

Posted on April 14, 2020 by Danzig

You spring clean your home. How about your skin? As we leave winter (and the dull, dry skin associated with it) behind, a quick way to refresh your glow is to try an at home chemical peel.

According to Dendy Engelman, MD, of Manhattan Dermatology and Cosmetic Surgery in New York, "its a method of exfoliation that uses a powerful dose of acids to weaken the cellular bonds between skin cells in the dermis. This helps to slough away dead, dull-looking cells, reveal healthy cells, reduce hyperpigmentation and improve skin texture."

"The main difference between the acids used in chemical peels is particle size. AHAs, or alpha hydroxy acids, are the smallest, then comes the BHAs, or beta hydroxy acids, followed by the PHAs, or polyhydoxy acids, which have the largest molecules," explains Engelman. "In-office procedures use stronger concentrations, which penetrate deeper into the skin, thus revealing more noticeable results as compared to an at-home peel, but because of their strength, they should only be administered by a licensed practitioner."

It depends on what youre looking to troubleshoot. If you are acne-prone or tend to easily get blackheads, BHA are your best bet. "Beta hydroxy acids like salicylic acid or willow bark extract have keratin-dissolving properties that can break down dead skin cell build up and decongest pores," says Engelman.

If you have dry or dull skin, Engelman recommends an AHA. "Alpha hydroxy acids like glycolic or lactic acid has the smallest particle size, meaning it is the most effective at breaking down the cellular bonds, which in turn, helps to reveal new, fresh skin cells." What this means for you: Major glow.

If you have sensitive skin that is easily irritated, try a PHA. "Polyhydroxy acids like gluconolactone or lactobionic acids have a larger molecular structure than AHAs and BHAs, which means they take longer to penetrate the skin and they wont penetrate as deeply, so theyre a much milder way to exfoliate," explains Engelman.

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"Before you commit to using an at-home peel, there are a couple of questions you need to ask yourself, such as: Are you using a retinol or retinoid? Are you using any other exfoliating products (such as a scrub), and are you going to shave around that area of skin?" says Engelman. "All of these things remove the top layer of your skin so adding a peel to the mix can deplete your epidermis and compromise your skin barrier. If you answered yes to any of those questions, Id recommend stopping them for three days before and after you use a peel to minimize irritation."

A good practice when introducing an active ingredient (like retinol or chemical peels) into your skincare regimen is to start slow. "I always recommend starting off with one to two times a week at firstmaybe even once every two weeks for people with very sensitive skin," advises Engelman. See how your skin reacts and then you can increase usage as needed. "The biggest mistake people make with exfoliants and with any products is over-doing it."

Next, post-peel care is very important. "You want to use an occlusive moisturizer, which is designed to prevent water loss in your skin. Preventing water loss allows your skins natural oils to nourish the newly revealed, younger skin cells, says Engelman. Look for moisturizers that have ceramides, hyaluronic acid, and peptides to strengthen the skin barrier."

And last but certainly not least: "It is important to limit sun and wind exposure by applying a broad-spectrum sunscreen daily, wearing protective clothing and staying indoors during peak hours (between 10 am and 4 pm), since your skin is more vulnerable to environmental aggressors after a peel."

OK, now that weve all graduated chemical peel 101, lets talk shop. Ahead are ten of our (and Dr. Dendys) favorite at-home peels.

This cult peel has been a favorite amongst dermatologists, estheticians and beauty editors alike. (And fun fact: Its celebrating a milestone anniversary of 20 years!) The peels were created by a top New York derm and were one of the first at-home options available to the masses. Dendy likes them because they "contain both alpha and beta hydroxyl acids like salicylic acid, glycolic acid, malic acid, which is a great combination to tackle a variety of skin issues including blocked pores, dull skin and hyperpigmentation." We like how easy they are to use. Just swipe the first pad over skin, wait two minutes and follow up with the second pad to finish.

$88 at Sephora

For the easily irritated, these gentle pads are a safe bet. Made with natural beta and alpha hydroxy acids (from wintergreen and Australian caviar lime, respectively) and balanced with jasmine and burdock root extracts, youll get the skin clarifying benefits of exfoliating without any afterburn or redness.

$65 at Dermstore

For any face mask lovers out there, consider this as your weekly treatment. Dendy likes that it "combines powerful botanical enzymes with salicylic acid and eco-friendly microbeads to provide an ideal combination of physical and chemical exfoliation." Just smooth it over damp, clean skin in a thin, even layer and let sit for five minutes before rinsing off using small, circular motions.

$95 at Dermstore

Another option that combines both physical and chemical exfoliation, these wine-soaked pads are a cult favorite within the K-beauty community. Each wipe is made with a lattice-woven gauze that gently scrubs away surface debris, while the blend of lactic and glycolic acids tackle anything thats left behind. (Youll want to rinse this off after a few minutes because it has a slightly sticky residue.)

Buy It $23

Inspired by the chemical peels Gwyneth used to get at her derms office, this weekly treatment is packed with an impressive 15 percent glycolic acid (making it one of the most potent at-home peels weve ever tried). To use, slip your fingertips inside the glove and swipe the soft side over the delicate skin of your face and the textured side over your neck, chest and shoulders. Note: You will likely feel a tingling sensation at first, but you will also wake up with a noticeable glow.

Buy It $125

Lets be clear: The "baby" in "babyfacial" is referring to how soft and silken this peel makes your skin feel after using it. It has nothing to do with its strengthwhich is pretty darn potent with a whopping 25 percent blend of AHAs. (Thats glycolic, tartatic, lactic and citric acids, by the way.) It also features two percent BHA to keep pores clear and pumpkin ferment extract to really get the job done. As a result, the glow is real, yall (but dont use it more than once a week).

$80 at Sephora

For those of us with stubborn blackheads and breakouts, these peach-scented pads are a godsend. Formulated with both salicylic and glycolic acids, they work double duty to clear pores of excess oil while dissolving any dead skin cells that sit on and beneath the surface. Within a few weeks of use, weve noticed that our normally speckled noses are much clearer.

$46 at Dermstore

Gentle on your walletand your skin. With a blend of lactic and glycolic acid (plus vitamins A and E), this overnight treatment sloughs off dead skin cells while you sleep. Allantoin and rosehip add a buffer, so your skin doesnt get dry or irritated. Oh, and this budget brand is also clean, vegan, cruelty-free and nothing in the line (including this peel) costs over 20 dollars.

$20 at Dermstore

What do Demi Lovato, Lili Reinhart and this beauty editor have in common? A love for this delicious mask from celebrity aesthetician Rene Rouleau. Jam packed with four different acids, bromelain (an exfoliating enzyme derived from pineapple), blueberry, raspberry seed oil and strawberry, it also looks and smells like a berry jam. We use it as a weekly preventative measure against future breakouts (and a brighter visage).

$89 at Rene Rouleau

For a gradual glow, Dendy recommends this 4-week treatment, which combines PHA, AHA, and idebenone (a supercharged antioxida
nt) to exfoliate the skin, soften fine lines, and improve the overall radiance and evenness of your skin tone.

$162 at Elizabeth Arden

RELATED: 5 DIY Face Masks You Can Make with Things in Your Pantry

COVID-19 linked to neurological symptoms, analysis finds – Clinical Daily News – McKnight’s Long Term Care News

Posted on April 14, 2020 by Danzig

Neurologic problems are common in patients with COVID-19, and in some cases are the first symptoms seen, according to a new analysis of patient data.

Among 214 patients hospitalized for COVID-19 in early 2020, 34% had neurologic issues, investigators found. In addition, patients with the most severe illness had significantly more of these problems, including acute cerebrovascular events, impaired consciousness, and muscle injury, reported Bo Hu, M.D., Ph.D., from Huazhong University of Science and Technology, Wuhan, China.

Most neurologic symptoms came early in the illnesses course. Symptom categories included:

Impaired consciousness included change of consciousness level (somnolence, stupor, and coma) and consciousness content (confusion and delirium).

Notably, some patients with fever and headache were admitted to the neurology ward after COVID-19 was ruled out. Days later, they developed established COVID-19 symptoms (cough, throat pain, lower lymphocyte count and lung scan signs) and were transferred back to the isolation ward.

Full findings were published Friday in JAMA Neurology.

In other coronavirus news:

Pharmacists permitted to order and administer COVID-19 tests: Licensed pharmacists may now order and administer COVID-19 tests approved by the U.S. Food and Drug Administration, the Department of Health and Human Services announced last week. The directive aims to improve testing access.

CDC confirms: Elders and males account for more coronavirus hospitalizations: The COVID-19 hospitalization rate for people 65 and older was 13.8 per 100,000, compared to a rate of 4.6 per 100,000 overall, preliminary data from March shows. Males may be disproportionately affected by COVID-19 compared with females, and black populations might be disproportionately affected as well, the agency reported.

Face masks offer slight protection from flu-like illness: Surgical-grade face masks provide modest protection against flu-like illness, according to a new study. Researchers from the University of East Anglia say there is enough evidence to support their use by vulnerable people, including patients and care providers in high-risk situations such as healthcare settings.

Acute Neurologic Deficit Linked to Salicylate Toxicity – MPR – Monthly Prescribing Reference

Posted on April 14, 2020 by Danzig

A recently published report describes the case of a 61-year-old female patient with a history of stroke that experienced an acute focal neurologic deficit due to salicylate toxicity and highlights the importance of considering this diagnosis and initiating treatment as quickly as possible.

In the emergency department (ED), the patient reported experiencing hemiparesis in her upper and lower extremities after waking up that morning. Further questioning revealed that over the past 2 weeks, the patient had been feeling generally unwell, anxious, and had experienced persistent chest pressure, which she treated with aspirin.

The patients past medical history included essential hypertension, generalized anxiety disorder, and a previous ischemic stroke with an associated seizure disorder. She stated that her seizure disorder was well controlled with diazepam and phenobarbital, however, she had not taken either medication the week prior to her ED presentation due to her illness. Additionally, the patient stated that she was not taking antiplatelet or anticoagulant drugs at the time.

After her arrival, the patient became confused and began experiencing tinnitus, shortness of breath, and blurred vision. Due to her neurologic presentation, age, and past medical history, recurrent stroke or transient ischemic attack were initially considered. After these diagnoses were excluded through further evaluation, laboratory findings revealed a mixed acid-base disorder with a wide anion gap metabolic acidosis and respiratory alkalosis.

Upon further questioning, the patient admitted to excessive use of salicylate over the previous 2 to 3 weeks. Laboratory findings revealed her initial serum salicylate level to be 78.1mg/dL (upper therapeutic limit, 19.9mg/dL).

The patient was treated with oral activated charcoal and intravenous sodium bicarbonate, potassium and dextrose. The patients symptoms completely resolved within 48 hours of her presentation to the ED.

The delay in diagnosis was a concern, considering the potentially fatal nature of salicylate toxicity and the importance of early treatment, the authors concluded, adding that physicians should maintain a high index of suspicion for salicylate toxicity in patients who present with acute neurologic symptoms, and medication history should include direct questioning for salicylate use.

Reference

Delaney TM, Helvey JT, Shiffermiller JF. A Case of Salicylate Toxicity Presenting with Acute Focal Neurologic Deficit in a 61-Year-Old Woman with a History of Stroke [published online February 15, 2020]. American Journal of Case Reports. doi: 10.12659/AJCR.920016.

A third of COVID-19 patients have neurological problems – The Dubrovnik Times

Posted on April 14, 2020 by Danzig

Coronavirus not only causes fever, cough and breathing problems, but also neurological problems such as headache and dizziness, a new study has found. The study was conducted by Chinese scientists on patients in Wuhan, the origin of the pandemic, and published in JAMA Neurology.

They reported that a third of the 214 patients they examined showed signs of a virus affecting the nervous system. Earlier, there were cases where patients suffering from covid-19 lost their sense of smell and taste.

These symptoms indicate that the brain was also affected in some way, commented infectious disease specialist Bernd Salzberger of the University Hospital in Regensburg. "But there are very few studies on the effects of coronavirus on patients' brains. We are still tapping in the dark," he added.

The study from Wuhan was based solely on medical history, laboratory findings and radiological examinations of 214 patients. Neurologist Ling Mao from the Huazhong Faculty of Science and Technology wrote that 78 patients (36.4 percent) had neurological problems.

Most often it was dizziness and headache. In addition, 12 of them lost their sense of taste and 11 of them smell. Six patients also suffered a stroke. But Chinese scientists are uncertain whether these symptoms are due to the disease itself or are part of the body's response to inflammatory processes.

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A third of COVID-19 patients have neurological problems - The Dubrovnik Times

Telemedicine Market demand to reach USD 175 Bn by 2026: Global Market Insights, Inc. – GlobeNewswire

Posted on April 14, 2020 by Danzig

Selbyville, Delaware, April 14, 2020 (GLOBE NEWSWIRE) --

Global Market Insights, Inc. has recently added a new report on telemedicine market which estimates the global market valuation for telemedicine will cross US$ 175 billion by 2026. Growing cases of COVID-19 infections across the globe is one of the significant factors boosting the market growth. For instance, total active COVID-19 cases have reached about 1.4 million cases across the globe.

Maintaining social distancing and self-quarantine are of key importance in containing the spread of corona virus. This have led to few countries taking stringent measures such as partial or complete lockdown. Which supports increasing adoption of telemedicine services to avail healthcare services. Also, various stringent regulations that were imposed on practicing telemedicine have also been relaxed. Such favorable government policies and growing inclination of patients towards virtual visits will propel the telemedicine market growth.

Request for a sample of this research report @ https://www.gminsights.com/request-sample/detail/3129

Tele-monitoring services market accounted for revenue share of about 29% in 2019 and similar trend is expected during the analysis period. Tele-monitoring services can be used to monitor those patients that are suffering from flu-like symptoms but are negative for COVID-19 infection. Moreover, tele-monitoring reduces the overall burden on the medical fraternity, thereby increasing their access to those patients that are suffering from serious ailments.

Telehospital market will witness more than 19% growth during 2020 to 2026. As the medical and paramedical personnel are at higher risks of COVID-19 infections, the demand for telehospital services is expected to increase in the future. For instance, more than 60 doctors have died in Italy due to the COVID-19 pandemic. Thus, with increasing number of healthcare personnel getting infected by the corona virus, the need for telehospital services is likely to increase during the analysis timeframe.

Neurology segment was valued at around USD 5.5 billion in 2019 and is anticipated to witness significant growth through 2026. Increasing incidence of Parkinsons disease, Alzheimers disease, autism, and epilepsy will increase the application of telemedicine in neurology. Growing demand for tele-neurology services especially amongst the older patient population will drive the telemedicine market for neurology. Moreover, with few countries implementing partial or complete lockdown, patients suffering from various neurological disorders will increasingly adopt telemedicine services.

Browse key industry insights spread across 200 pages with 283 market data tables & 9 figures & charts from the report, Telemedicine Market Share & Forecast, 2020 2026 in detail along with the table of contents:

https://www.gminsights.com/industry-analysis/telemedicine-market

Call centers segment is forecasted to show steady expansion at 18.8% CAGR from 2020 to 2026. Increasing influence of home quarantine and social distancing will lead to a spike in number of calls received by various telemedicine call centers. Moreover, companies are expanding their capabilities to serve and cater the exponential increase in the virtual call volume. Aforementioned factors will drive the market growth.

China telemedicine market is projected to expand at a CAGR of more than 23% over the forecast period. The regional growth is attributed to the factors such as large number of COVID-19 infections and growing target geriatric population. Moreover, with implementation of partial lockdown in certain provinces of China, the patients are increasingly adopting telemedicine services. Factors such as increasing usage of smartphones and internet among the Chinese population will further drive the market growth.

Some major findings of the telemedicine market report include:

Some of the prominent players operating in the e-health market are Allscripts Healthcare Solutions Inc, AMD Global Telemedicine, American Well, BioTelemetry, Cisco Systems, Honeywell International Inc, Koninklijke Philips N.V., and Teladoc. These players adopt various strategies such as acquisitions, collaborations, mergers, partnerships, geographic expansion. For instance, in May 2018, Allscripts signed an agreement to acquire HealthGrid Holding Company. This acquisition will enable significant expansion of FollowMyHealth platform portfolio and spur revenue generation.

Make an inquiry for purchasing this report @ https://www.gminsights.com/inquiry-before-buying/3129

Partial chapters of report table of contents (TOC):

Chapter 2. Executive Summary

2.1. Telemedicine industry 360synopsis, 2015 - 2026

2.1.1. Business trends

2.1.2. Service trends

2.1.3. Type trends

2.1.4. Specialty trends

2.1.5. Delivery mode trends

2.1.6. Regional trends

Chapter 3. Telemedicine Industry Insights

3.1. Industry segmentation

3.2. Industry landscape, 2015 2026

3.3. Industry impact forces

3.3.1. Growth drivers

3.3.1.1. Rising cases of COVID-19 infections across the globe

3.3.1.2. Increasing prevalence of chronic diseases

3.3.1.3. Growing number of smartphone users

3.3.1.4. Technological advancements related to mobile phones and internet

3.3.1.5. Greater need for cost-saving in healthcare delivery

3.3.1.6. Long waiting time in hospitals for disease treatment

3.3.1.7. Favorable government initiatives

3.3.2. Industry pitfalls & challenges

3.3.2.1. Security and privacy concerns

3.3.2.2. Lack of knowledge and trust in developing countries

3.4. Growth potential analysis

3.4.1. By service

3.4.2. By type

3.4.3. By specialty

3.4.4. By delivery mode

3.5. COVID-19 impact analysis

3.5.1. Impact of COVID-19 on major markets

3.5.1.1. Overview

3.5.1.2. U.S.

3.5.1.3. Canada

3.5.1.4. Germany

3.5.1.5. UK

3.5.1.6. France

3.5.1.7. Spain

3.5.1.8. Italy

3.5.1.9. Switzerland

3.5.1.10. China

3.5.1.11. Japan

3.5.1.12. Saudi Arabia

3.5.2. Impact of COVID-19 on industry segments, by 10 major markets (2020)

3.5.2.1. Teleconsultation

3.5.2.2. Tele-monitoring

3.5.2.3. Telehome

3.5.2.4. Mental Health

3.5.2.5. Respiratory illness

3.5.3. Impact of COVID-19 on industry competition

3.5.3.1. Strategy

3.5.3.2. Product portfolio

3.5.3.3. Business growth

3.6. Reimbursement scenario

3.6.1. U.S.

3.6.2. Europe

3.7. Telemedicine modalities

3.8. Telemedicine projects

3.9. Government initiatives

3.10. Telemedicine future trends

3.11. Analyst recommendations

3.12. Porters analysis

3.13. Competitive landscape, 2019

3.13.1. Strategy dashboard

3.14. PESTEL analysis

Browse reports complete table of contents (ToC):https://www.gminsights.com/toc/detail/telemedicine-market

About Global Market Insights

Global Market Insights, Inc., headquartered in Delaware, U.S., is a global market research and consulting service provider, offering syndicated and custom research reports along with growth consulting services. Our business intelligence and industry research reports offer clients with penetrative insights and actionable market data specially designed and presented to aid strategic decision-making. These exhaustive reports are designed via a proprietary research methodology and are available for key industries such as chemicals, advanced materials, technology, renewable energy and biotechnology.

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Telemedicine Market demand to reach USD 175 Bn by 2026: Global Market Insights, Inc. - GlobeNewswire

Does Long-Term Exposure to Air Pollution Lead to a Steeper Rate of Cognitive Decline? – Newswise

Posted on April 14, 2020 by Danzig

EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, APRIL 8, 2020

Newswise MINNEAPOLIS People who live in urban areas with higher levels of air pollution may score lower on thinking and memory tests and may also lose cognitive skills faster over time, or it is possible they also may not, according to a study published in the April 8, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology. Researchers examined the association of air pollution levels and cognitive impairment and decline in participants in two large epidemiological studies. They found an association between the air pollution and cognitive decline in one study group but not in the other.

As people live longer lives and the aging population grows, age-related cognitive decline is a growing public health concern with profound social, economic and health effects, so finding ways to reduce the risk is important, said study author Erin R Kulick, Ph.D., M.P.H., of Brown University School of Public Health in Providence, R.I., and a member of the American Academy of Neurology. Air pollution can affect large populations of people because it has known cardiovascular risks, and previous research has found that it may also contribute to cognitive decline. However, the results of our research were mixed.

The study involved people living in the Northern Manhattan area of New York City who were enrolled in two larger long-term studies: 5,330 people with an average age of 75 enrolled in the Washington Heights-Inwood Community Aging Project; and 1,093 people with an average age of 70 enrolled in the Northern Manhattan Study. Both groups were ethnically and racially diverse with black, white and Hispanic participants.

All participants were given medical exams at the beginning of the study as well as cognitive tests to measure memory, language skills and executive function, which involves thinking skills like organizing, planning and completing tasks.

The group from the Washington-Heights-Inwood study of 5,330 participants was followed an average of seven years with six rounds of follow-up testing every 18 months to two years. The Northern Manhattan study group of 1,093 participants was followed for five years with one follow-up round of testing.

Researchers used the residential addresses of each participant to determine their exposures to three air pollutants. Those pollutants were nitrogen dioxide and two groups of particulate matter, particles of liquids or solids suspended in air that were less than 2.5 microns in diameter called fine particulate matter and particles that were less than 10 microns in diameter called respirable particulate matter. Average levels of air pollutants were similar for both groups of participants. In each group, participants were divided into four groups based on their air pollution exposure.

Researchers found that participants in the Washington-Heights Inwood study were exposed to a yearly average of 32 parts per billion of nitrogen dioxide, 13 micrograms per cubic meter (g/m3) of fine particulate matter and 21 g/m3 of respirable particulate matter The U.S. Environmental Protection Agency (EPA) considers up to 53 parts per billion to be a safe level of yearly average exposure to nitrogen dioxide, up to 12 g/m3 for fine particulate matter and up to 50 g/m3 for respirable particulate matter.

While the levels were in the range considered safe by the EPA, its possible that these results reflect higher levels from an earlier point in time. It also raises the question of whether the federal levels are low enough to protect peoples health, said Kulick.

The researchers found that in the Washington Heights-Inwood group, people with greater exposure to higher levels of air pollution had lower scores on the tests at the beginning of the study and more rapid rates of decline.

Exposure to nitrogen dioxide was linked to an accelerated rate of cognitive decline comparable to one year of aging. Results were similar for fine and respirable particulate matter.

In the Northern Manhattan group, researchers did not find an association between cognitive function and air pollution. Kulick says the difference in results may be because the second group was much smaller and only had one round of follow-up compared to six rounds for the first group.

A strength of our study was that we were able to analyze the rates of cognitive decline over time so it adds important findings to the growing body of scientific evidence about air pollution and its effects on the brain health of older adults, Kulick said. More research is needed to better understand our studys mixed results. The good news for public health is that air pollution can be reduced, and has been in some cities, through laws and regulation. But there are still millions of people living in areas of the United States where major air quality improvements are needed.

A limitation of the study was that while it included levels of air pollution near a persons residence, it did not account for levels of pollution at the workplace or elsewhere. Also, many participants grew up in other countries and may have had different exposures to air pollution at younger ages.

The study was supported by the National Heart, Lung, and Blood Institute, the National Institute of Environmental Health, the National Institute of Aging and the Environmental Protection Agency.

Learn more about dementia at BrainandLife.org, home of the American Academy of Neurologys free patient and caregiver magazine focused on the intersection of neurologic disease and brain health. Follow Brain & Life on Facebook, Twitter and Instagram.

The American Academy of Neurology is the worlds largest association of neurologists and neuroscience professionals, with over 36,000 members. The AAN is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimers disease, stroke, migraine, multiple sclerosis, concussion, Parkinsons disease and epilepsy.

For more information about the American Academy of Neurology, visit AAN.com or find us on Facebook, Twitter, Instagram, LinkedIn and YouTube.

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Does Long-Term Exposure to Air Pollution Lead to a Steeper Rate of Cognitive Decline? - Newswise

Global Pediatric Neurology Devices Market- Industry Analysis and Forecast (2020-2027) by Product Type, Service, Neurological Subspecialties,…

Posted on April 14, 2020 by Danzig

Global Pediatric Neurology Devices Market was valued US$ XX Bn in 2019 and is expected to reach US$ XX Bn by 2027, at a nearby CAGR of 8.7 % during a forecast period.

Market Definition

Pediatric neurology is a branch of science raising to neurological disorders in children like frequent headaches and insomnia. The prevalence of neurological disorders in children is mounting rapidly. Neurological disorders are diseases of brain, spine, and nerves that connect them.

Market Dynamics

The report contains a detailed list of factors that will drive and restrain the growth of the pediatric neurology devices market. Government of developing economies are looking forward to accepting advanced technology from the developed regions to improve the quality of life of their citizen and also support the launch of medical devices for treating and aiding children with neurological disorders. Environmental factors could provoke genetic and epigenetic mutations as well as disease-related inflammatory events such as Alzheimers disease. However, the high cost related to diagnosis and monitoring of neurological diseases may hinder market growth.

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Global Pediatric Neurology Devices Segment analysis:

The report covers the segments in the pediatric neurology devices market such as product, services, neurological subspecialties, and application. Based on service, the electroencephalography segment is expected to grow at the highest X.6 % CAGR during the forecast period. Electroencephalography (EEG) Measures electrical potentials at scalp generated by underlying neurons particularly useful at diagnosing epilepsy and coma and also it monitors record of the electrical activity of the brain. Therapists highly rely on EEG procedures and video EEG to diagnose neonatal seizures and paroxysmal events and psychogenic nonepileptic seizures (PNES) respectively.

Global Pediatric Neurology Devices Market Regional analysis

North America dominates the pediatric neurology devices market share of XX % during the forecast period because of the rising incidence of diseases such as depression, epilepsy, and migraine, high healthcare spending, and cumulative government support for research & development. The 3rd International Conference on Neurology and Brain Disorders were organized on 19-10, June 2019 at the Crowne Plaza Dublin Hotel, Dublin- Ireland helps for regional growth. Migraine is an extraordinarily prevalent neurological disease, affecting 39 million men, women and children in the U.S. and 1 billion worldwide in 2019.

According to the Neurological Alliance, estimated that there are 14.7 million neurological cases in 2019. According to a report published by UMKC School of Medicine, about 2.7 million people in the U.S are suffering by epilepsy and more than 45,000 new cases are diagnosed every year. Increasing the incidence of neurological disorders in the region, which increases the market potential for neurology drugs.

Country-wise Analysis:

Emerging economies, such as India and China, contribute to the growth of the market in APAC which will grow at a CAGR of XX%, because of increasing incidents of neurological disorders. The prevalence of neurological disorders is representing huge economic and social burden mainly in low income and developing regions where there is increased life expectancy and elevated aging populations, as well as neurological services and resources, which are rare and limited. Furthermore, factors such as the increasing demand for quality devices in the healthcare and flourishing healthcare technology is estimated to provide the drive to the market growth, which boosts the uptake of advanced equipment.

Key Development

The reports cover key developments in the pediatric neurology devices market as organic and inorganic growth strategies.

On January 2020: Abbotts has developed low dose neurostimulation for chronic pain. The Proclaim XR spinal cord stimulator can run for ten years using its internal battery, and patients can control its function using a paired iPhone. For chronic pain patients who may be helped by such therapy, it may result in a huge lifestyle improvement over many of their previous options. January 2020, The infinity Parkinsons by delivering deep brain stimulation(DBS) system, originally developed by St. Jude Medical that became part of Abbott, already has approval to stimulate the subthalamic nucleus (STN) and ventral intermediate nucleus (VIM) for the he treatment of Parkinsons, Essential Tremor, and some other movement disorders.

The objective of the report is to present a comprehensive analysis of the Global Pediatric Neurology Devices Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language. The report covers all the aspects of the industry with a dedicated study of key players that includes market leaders, followers and new entrants. PORTER, SVOR, PESTEL analysis with the potential impact of micro-economic factors of the market have been presented in the report. External as well as internal factors that are supposed to affect the business positively or negatively have been analyzed, which will give a clear futuristic view of the industry to the decision-makers.The report also helps in understanding Global Pediatric Neurology Devices Market dynamics, structure by analyzing the market segments and project the Global Pediatric Neurology Devices Market size. Clear representation of competitive analysis of key players by Application, price, financial position, Product portfolio, growth strategies, and regional presence in the Global Pediatric Neurology Devices Market make the report investors guide.

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Scope of the Global Pediatric Neurology Devices Market

Global Pediatric Neurology Devices Market, By Product Type

Neurosurgery Devices Neurostimulator Cerebrospinal Fluid (CSF) Management DevicesGlobal Pediatric Neurology Devices Market, By Service

Electroencephalogram Intrathecal Baclofen Therapy Neurological Evaluations Vagal Nerve StimulationGlobal Pediatric Neurology Devices Market, By Neurological Subspecialties

Neuro-Oncology Neuromuscular Neonatal Neurology Neuroimmunology Stroke OthersGlobal Pediatric Neurology Devices Market, By Application

Hospitals Healthcare Centers Neurological Research CentersGlobal Pediatric Neurology Devices Market, by Regions

North America Europe Asia-Pacific Latin America Middle East and Africa (MEA)Key Players operating in Global Pediatric Neurology Devices Market

Abbot Elana Inova Healthcare System Medtronic The Nemours Foundation Stryker Boston Scientific B.Braun Melsungen Integra LifeSciences St. Jude Medical

MAJOR TOC OF THE REPORT

Chapter One: Pediatric Neurology Devices Market Overview

Chapter Two: Manufacturers Profiles

Chapter Three: Global Pediatric Neurology Devices Market Competition, by Players

Chapter Four: Global Pediatric Neurology Devices Market Size by Regions

Chapter Five: North America Pediatric Neurology Devices Revenue by Countries

Chapter Six: Europe Pediatric Neurology Devices Revenue by Countries

Chapter Seven: Asia-Pacific Pediatric Neurology Devices Revenue by Countries

Chapter Eight: South America Pediatric Neurology Devices Revenue by Countries

Chapter Nine: Middle East and Africa Revenue Pediatric Neurology Devices by Countries

Chapter Ten: Global Pediatric Neurology Devices Market Segment by Type

Chapter Eleven: Global Pediatric Neurology Devices Market Segment by Application

Chapter Twelve: Global Pediatric Neurology Devices Market Size Forecast (2019-2026)

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State accuses Alamo doctor of attempting to assist in C-section while drunk – danvillesanramon.com

Posted on April 14, 2020 by Danzig

byRyan J. Degan

A doctor from Alamo is at risk of having her medical license revoked after the California Medical Board alleged that she attempted to assist with childbirth surgery at San Ramon Regional Medical Center while under the influence of alcohol.

Filed on March 26 by the state board, the complaint alleges that Dr. Michele Louise Riopelle, an obstetrician and gynecologist (OB/GYN) with San Ramon Regional at the time, was called in to assist in a caesarean section and reported to the hospital for the operation despite having a blood alcohol level of 0.30%.

The complaint alleges the doctor entered the operating room in an intoxicated state but did not take part in the C-section that night.

It was not immediately clear whether Riopelle was represented by an attorney. There is no written response to the complaint, nor any other documentation provided by Riopelle's side, in the California Medical Board online public document database.

Krista Deans, a spokesperson for San Ramon Regional, told DanvilleSanRamon.com on Tuesday, "Dr. Michele Riopelle is not practicing at San Ramon Regional Medical Center."

The incident occurred at approximately midnight on the night of July 31 to Aug. 1, when Riopelle was the on-call obstetrician for the San Ramon Regional labor and delivery department.

According to the Medical Board's complaint, after receiving the call that she was needed to assist in an operation, Riopelle arrived to the hospital within 40 minutes -- even though San Ramon Regional bylaws require a 30-minute response time for C-section assistance -- during which time nursing staff noticed she was "unsteady on her feet, slurring her speech, confused and incoherent."

According to the complaint, Riopelle denied taking any medication and claimed she was fine, but she was observed having difficulty washing her hands and was unable to tie her shoes or apply her mask correctly.

While nursing staff tried to prevent her from doing so, Riopelle allegedly insisted on entering the operating room where, in the presence of the patient's husband, she attempted to put on her gown and gloves. Eventually Riopelle had to be escorted out of the operating room after attempting to approach the patient, according to the complaint.

The complaint added that the attending OB/GYN was able to complete the C-section with assistance from a pediatrician prior to Riopelle entering the operating room.

Riopelle was taken to the hospital's emergency room, where she was noted to have "altered speech and poor coordination," according to the complaint. After claiming to have taken a muscle relaxant the previous day, Riopelle denied having consumed any alcohol.

Fearing a "neurological event" the emergency room physician performed a full neurological evaluation that included a CT scan, before a blood test revealed a 0.30% blood alcohol level, according to the complaint. Riopelle was then released to the care of her husband with a diagnosis of acute alcohol intoxication.

After charging Riopelle with inappropriate conduct, the Medical Board of California can revoke her license to practice, have it suspended or place her on probation.

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State accuses Alamo doctor of attempting to assist in C-section while drunk - danvillesanramon.com

Specialty Physicians Weigh in on the State of Practice After COVID-19 – Rheumatology Network

Posted on April 14, 2020 by Danzig

The negative impact of the COVID-19 pandemic on specialty medical practices may lift by the start of next month, according to a new report issued by the market research company Spherix Global Insights.

"Our frontline healthcare leaders are scared, worried, and frustrated. Collectively, they estimate it being eight to nine weeks before things begin to improve and 83 percent of those surveyed last week (April 1) expect things to get worse in the next two weeks. In the words of one neurologist, "(My greatest concern is) that it will linger on to some degree for much of the year and dramatically and permanently affect people's livelihoods, relationships, and dreams," according to a statement issued by Spherix.

The company surveyed 252 rheumatologists, dermatologists, gastroenterologists, nephrologists and neurologists early this month findng that office visits are down by at least 80 percent, despite the adoption of telemedicine. Doctors, the report said, have had challenges with telemedicine and are still unclear about reimbursement policies for the use of telemedicine in place of in-office visits. "Though telemedicine consults have seen successive increases each week, it is not coming close to bridging the gap, and some specialties are having a more difficult time than others," Spherix stated.

The drop in cases has placed financial strain on office-based practices, particularly for dermatologists and gastroenterologists who rely heavily on elective procedures. Many practices have furloughed or staff or laid off works altogehter. If the lockdown and pandemic continues for another two months, some private practices may not survive. "Those in smaller practices are most concerned," the report stated.

While 23 percent of physicians belive the stimulus package will help their practice, more than one-third anticipate little to no impact from government assistance and the majority of physicians have ranked President Trump's handling of the crisis "low satisfaction."

"Drugs associated with being more targeted regarding their immunosuppression and generally considered as having favorable safety profiles may come off the least scathed: Amgen's Otezla for psoriasis and psoriatic arthritis (PsA) and Takeda's Entyvio for inflammatory bowel disease (IBD), though the latter will be counter-balanced by tempered use of infusion products. For most leading brands in the autoimmune space, there have been minimal issues with the supply chain, the exceptions being hydroxychloroquine (84% of rheumatologists report issues) and Genentech's Actemra (34% of rheumatologists report issues). Products that require administration by a healthcare professional, such as Sun Dermatology's Ilumya for psoriasis, also face a challenging scenario," the report stated.

Drug suppliers, such as AbbVie, have been in frequent communication with dermatology, gastroenterology and rheumatology specialists. "It seems that AbbVie in particular is attempting to thwart any launch setbacks for their next generation JAK inhibitor (Rinvoq), as the company was listed the most frequently by rheumatologists as continuing to provide samples via mail and engage in e-detailing platforms."

"Nephrologists have been a bit more buffered than other specialists with regard to patient volume decreases, as their dialysis population continues to require thrice weekly treatment to survive. However, their patient population immunosuppressed kidney transplant patients, elderly dialysis patients receiving care in group settings, and a patient base with chronic kidney disease that typically has multiple other co-morbidities is associated with a significantly higher risk of COVID-19 complications. Over the past two weeks, nephrologists increasingly reported having action plans in place for dealing with a COVID-19 outbreak at a dialysis unit; the vast majority are prepared. Most of those surveyed give high satisfaction ratings to dialysis organizations, such as Fresenius and DaVita, and the American Society of Nephrology, for their communication around COVID-19. Only 22% feel that the pharmaceutical industry is providing a high level of support/communication, and more than half say that increased samples, largely to help bridge patients with financial hardship, would be appreciated."

Approximatley half of neurologists are now starting fewer multiple sclerosis patients on their first disease-modifying therapy (DMT) or switching patients to new treatments, compared to prior to the COVID-19 outbreak. "While concerns related to immunosuppression are definitely a factor, access to infusion centers and delayed scheduling of next doses may also be playing an increasing role in the decreased use, as three out of five neurologists indicate that at least some patients are having difficulty getting their Ocrevus treatments (compared to only 28% for a high-efficacy oral DMT like Novartis' Gilenya)."

Informative Report On Interventional Neurology Devices Market 2020 With keyplayer Abbott, DePuy Synthes, Medtronic, Stryker, Terumo, Acandis, Bayer,…

Posted on April 14, 2020 by Danzig

Interventional Neurology Devices Market Industry Forecast To 2024

Garner Insights has titled a new research report named as Interventional Neurology Devices Market 2020 to its consistently extending database. The report clarifies this through a series of channels which include data ranging from rudimentary data to an undeniable estimate. It consolidates all the fundamental factors that are foreseen to change inside the market. The information would thus be used to heighten an organizations standing in the worldwide market.

Interventional neurology refers to endovascular, catheter-based techniques using fluoroscopy and angiography to diagnose and treat vascular disease of the central nervous system. Neurointerventional procedures use imaging technology and are minimally invasive, meaning they can be accomplished through small incisions, rather than open surgery.

Get a Sample Report @:https://www.garnerinsights.com/Global-Interventional-Neurology-Devices-Market-2018-by-Manufacturers-Regions-Type-and-Application-Forecast-to-2023#request-sample

Based on the industrial chain, this report mainly elaborates the definition, types, applications and major players of Interventional Neurology Devices market in details. Deep analysis about Interventional Neurology Devices market status (2014-2019), enterprise competition pattern, advantages and disadvantages of enterprise products, industry development trends (2020-2024), regional industrial layout characteristics and policies has also be included.

Major Manufacturer Detail:Abbott, DePuy Synthes, Medtronic, Stryker, Terumo, Acandis, Bayer, Boston Scientific, Biosensors International, evonos, Merit Medical Systems, MicroPort Scientific, Neurosign, Penumbra, Spiegelberg, Surtex Instruments

The Important Type Coverage:Carotid Artery Angioplasty and Stenting, Carotid Artery Stents, Embolic Protection Systems, Balloon Occlusion Devices, Aneurysm Coiling and Embolization Devices, Flow Diversion Devices, Liquid Embolic Devices, Embolic coils, Micr-Support Devices, Microcatheters

Segment by ApplicationsArteriovenous Malformation and Fistulas, Cerebral Aneurysms, Schemic Strokes, Intracranial Atherosclerotic Disease

The Interventional Neurology Devices report consists of streamlined financial data obtained from various research sources to provide specific and trustworthy analysis. Evaluation of the key market trends with a positive impact on the market over the following couple of years, including an in-depth analysis of the market segmentation, comprising of sub-markets, on a regional and global basis. The report also provides a detailed outlook of the Interventional Neurology Devices market share along with strategic recommendations, on the basis of emerging segments.

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Some Of The Major Geographies Included In This Study:

North America (U.S and Canada and Rest of North America)Europe (Germany, France, Italy and Rest of Europe)Asia-Pacific (China, Japan, India, South Korea and Rest of Asia-Pacific)LAMEA (Brazil, Turkey, Saudi Arabia, South Africa and Rest of LAMEA)

Some major points covered in this Interventional Neurology Devices Market report:

1. An overall outlook of the market that helps in picking up essential data.2. The market has been segmented on the basis of the product types, applications, end-users, as well as the industry verticals, in light of numerous factors. Considering the market segmentation, further analysis has been carried out in an effective manner. For better understanding and a thorough analysis of the market, the key segments have further been partitioned into sub-segments.3. In the next section, factors responsible for the growth of the market have been included. This data has been collected from the primary and secondary sources and has been approved by the industry specialists. It helps in understanding the key market segments and their future trends.4. The report also includes the study of the latest developments and the profiles of major industry players.5. The Interventional Neurology Devices market research report also presents an eight-year forecast on the basis of how the market is predicted to grow.

View Full Report @ https://garnerinsights.com/Global-Interventional-Neurology-Devices-Market-2018-by-Manufacturers-Regions-Type-and-Application-Forecast-to-2023

About Us:Garner Insights is a Market Intelligence and consulting firm with an all-inclusive experience and vast knowledge of the market research industry.Our vast storage of research reports across various categories, gives you a complete view of the ever changing and developing trends and current topics worldwide. Our constant endeavor is to keep on improving our storage information by providing rich market reports and constantly improving them.

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Informative Report On Interventional Neurology Devices Market 2020 With keyplayer Abbott, DePuy Synthes, Medtronic, Stryker, Terumo, Acandis, Bayer,...

Large-scale analysis links glucose metabolism proteins in the brain to Alzheimer’s disease biology – National Institute on Aging

Posted on April 14, 2020 by Danzig

In the largest study to date of proteins related to Alzheimers disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers. The findings suggest that sets of proteins that regulate glucose metabolism, together with proteins related to a protective role of astrocytes and microglia the brains support cells are strongly associated with Alzheimers pathology and cognitive impairment.

The study, part of the Accelerating Medicines Partnership for Alzheimers Disease (AMP-AD), involved measuring the levels and analyzing the expression patterns of more than 3,000 proteins in a large number of brain and cerebrospinal fluid samples collected at multiple research centers across the United States. This research was funded by the National Institutes of Healths National Institute on Aging (NIA) and published April 13 in Nature Medicine.

This is an example of how the collaborative, open science platform of AMP-AD is creating a pipeline of discovery for new approaches to diagnosis, treatment and prevention of Alzheimers disease, said NIA Director Richard J. Hodes, M.D. This study exemplifies how research can be accelerated when multiple research groups share their biological samples and data resources.

The research team, led by Erik C.B. Johnson, M.D., Ph.D, Nicholas T. Seyfried, Ph.D., and Allan Levey, M.D., Ph.D., all at the Emory School of Medicine, Atlanta, analyzed patterns of protein expression in more than 2,000 human brain and nearly 400 cerebrospinal fluid samples from both healthy people and those with Alzheimers disease. The papers authors, which included Madhav Thambisetty, M.D., Ph.D., investigator and chief of the Clinical and Translational Neuroscience Section in the NIAs Laboratory of Behavioral Neuroscience, identified groups (or modules) of proteins that reflect biological processes in the brain.

The researchers then analyzed how the protein modules relate to various pathologic and clinical features of Alzheimers and other neurodegenerative disorders. They saw changes in proteins related to glucose metabolism and an anti-inflammatory response in glial cells in brain samples from both people with Alzheimers as well as in samples from individuals with documented brain pathology who were cognitively normal. This suggests, the researchers noted, that the anti-inflammatory processes designed to protect nerve cells may have been activated in response to the disease.

The researchers also set out to reproduce the findings in cerebrospinal fluid. The team found that, just like with brain tissue, the proteins involved in the way cells extract energy from glucose are increased in the spinal fluid from people with Alzheimers. Many of these proteins were also elevated in people with preclinical Alzheimers, i.e., individuals with brain pathology but without symptoms of cognitive decline. Importantly, the glucose metabolism/glial protein module was populated with proteins known to be genetic risk factors for Alzheimers, suggesting that the biological processes reflected by these protein families are involved in the actual disease process.

Weve been studying the possible links between abnormalities in the way the brain metabolizes glucose and Alzheimers-related changes for a while now, Thambisetty said. The latest analysis suggests that these proteins may also have potential as fluid biomarkers to detect the presence of early disease.

In a previous study, Thambisetty and colleagues, in collaboration with the Emory researchers, found a connection between abnormalities in how the brain breaks down glucose and the amount of the signature amyloid plaques and tangles in the brain, as well as the onset of symptoms such as problems with memory.

This large, comparative proteomic study points to massive changes across many biological processes in Alzheimers and offers new insights into the role of brain energy metabolism and neuroinflammation in the disease process, said Suzana Petanceska, Ph.D., program director at NIA overseeing the AMP-AD Target Discovery Program. The data and analyses from this study has already been made available to the research community and can be used as a rich source of new targets for the treatment and prevention of Alzheimers or serve as the foundation for developing fluid biomarkers.

Brain tissue samples came from autopsy of participants in Alzheimers disease research centers and several epidemiologic studies across the country, including the Baltimore Longitudinal Study of Aging (BLSA), Religious Orders Study (ROS) and Memory and Aging Project (MAP), and Adult Changes in Thought (ACT) initiatives. The brain collections also contained samples from individuals with six other neurodegenerative disorders as well as samples representing normal aging, which enabled the discovery of molecular signatures specific for Alzheimers. Cerebrospinal fluid samples were collected from study participants at the Emory Goizueta Alzheimers Disease Research Center. These and other datasets are available to the research community through the AD Knowledge Portal, the data repository for the AMP-AD Target Discovery Program, and other NIA supported team-science projects operating under open science principles.

This press release describes a basic research finding. Basic research increases our understanding of human behavior and biology, which is foundational to advancing new and better ways to prevent, diagnose, and treat disease. Science is an unpredictable and incremental process each research advance builds on past discoveries, often in unexpected ways. Most clinical advances would not be possible without the knowledge of fundamental basic research.

The research in this study is funded by NIH grants R01AG053960, R01AG057911, R01AG061800, RF1AG057471, RF1AG057470, R01AG061800, R01AG057911, R01AG057339, U01AG061357, P50AG025688, RF1AG057470, RF1AG051633, P30AG10161, R01AG15819, R01AG17917, U01AG61356, R01AG056533, K08NS099474, U01AG046170, RF1AG054014, RF1AG057440, R01AG057907, U01AG052411, P30AG10124, U01AG046161, R01AG050631, R01AG053960, R01AG057339, U01AG061357, P50AG005146, U24NS072026, and P30AG19610.

Reference: Johnson ECB et al. Large-scale proteomic analysis of Alzheimers disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. 2020 Apr 13. doi:10.1038/s41591-020-0815-6

About the National Institute on Aging (NIA): NIA leads the U.S. federal government effort to conduct and support research on aging and the health and well-being of older people. Learn more about age-related cognitive change and neurodegenerative diseases via NIAs Alzheimer's and related Dementias Education and Referral (ADEAR) Center website. For information about a broad range of aging topics, visit the main NIA website and stay connected.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit the NIH website.

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Large-scale analysis links glucose metabolism proteins in the brain to Alzheimer's disease biology - National Institute on Aging

Lead the way, Kansas | Gaz – Emporia Gazette

Posted on April 14, 2020 by Danzig

A biochemistry professor at Kansas State University has exactly the right idea: Kansas should aggressively test as many people as possible for the coronavirus.

In a letter to the editor earlier this week, Sally Newton suggested that our state could prove to the rest of the country that this is the way to stop a viral pandemic.

Kansas is not that big, relatively speaking, with a population of 2.9 million people, about a third the size of New York City. The number of confirmed cases is around 500; in New York, there are more than 47,000 confirmed cases

About 5,400 people in Kansas have been tested.

Authorities have doled out the tests in a miserly manner in our state, and in the U.S. generally, because of short supplies. We cant blame local authorities for setting priorities in testing. It is an enormous failure on the part of the federal government.

Other countries are taking a far more aggressive approach: In Germany, theyre testing 500,000 people a week, and theyre looking to ramp up to 200,000 per day. England is aiming for 25,000 people a day by the end of April. Sweden and Austria are at 15,000 tests per day.

The consequence of a lack of testing in the U.S. has been that governments have to shut down everything in order to keep everybody away from each other. Social distancing is a logical response, under those circumstances, in order to keep from overwhelming the health care system. Citizens have to do their part by following those rules, and nothing were saying here is intended to undermine that. In other words, stay home. Its our best shot right now.

But its not ideal. Shuttered businesses mean lost jobs, among other things.

In Kansas, we could pretty much test everybody if the right people and political forces got behind it. Sally Newton, the K-State biochemistry professor, said in the letter we published Sunday, that it could be called the Kansas Experiment, and that could show the rest of the country that its the way to move forward.

Mass testing could allow us to quarantine people who actually have the virus or whove been in contact with people carrying it. That would prevent infected people who dont yet show symptoms from giving it to others. It could also shorten the duration of social distancing, if done right.

Manhattan Mercury

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Lead the way, Kansas | Gaz - Emporia Gazette

NRL brings in top biochemical and weapons expert for season restart – The Age

Posted on April 14, 2020 by Danzig

Strict Queensland border controls and problems with shipping the Warriors across the Tasman for a 14-day isolation period means the NRL will ramp up its logistics around having teams housed, training and playing in Sydney for the season restart.

The biochemical and weapons expert is seen as pivotal in setting up a risk analysis and mapping out how match-day activities will function in empty stadiums.

Balls were disinfected at Lottoland during the opening round clash between Manly and Melbourne due to coronavirus fears.Credit:Getty Images

The NRL is poised to temperature check players three times on game day. Powerbrokers have even discussed the set-up of multiple areas - a dirty zone, transition zone and clean zone - to separate athletes and officials.

No detail has been spared, with discussion ranging from what time broadcasters need to lay cabling at venues to how club officials handle dirty playing gear after matches.

The biosecurity proposals are expected to be lodged with the Rugby League Players Association and clubs within a week.

It is expected they will also be shown to the relevant federal and state government officials, many of whom have questioned the NRL's "ambitious" timeline to relaunch the season.

Queensland Premier Annastacia Palaszczuk has refused to relax border controls by providing exemptions for the Broncos, Cowboys and Titans to fly in and out of NSW for matches. She doubled down on Tuesday, saying she hoped there wouldn't be a State of Origin series played this year.

"I hope there's not [an Origin series midway through 2020]," she told Nine, the publisher of this masthead. "We always have a State of Origin, but how can you have it [this year]? Maybe in December? Let's keep our fingers crossed."

But Queensland Rugby League chairman Bruce Hatcher said it was premature to rule out Brisbane hosting an Origin match this year - let alone scrapping the financial juggernaut.

I don't want to get into a slanging match with the Premier, but I think it's far too early to call that

"I don't want to get into a slanging match with the Premier, but I think it's far too early to call that," he said. "I really want to see one of the matches played here in Queensland - at least one - because it's a highlight of the year for anyone who follows sport or big events.

"I know the Premier is a real fan of Origin. She turns up to the games and is a great supporter of the Maroons. Unless she's got more information than what she's told us about, maybe she's making a comment to slow people down a bit.

"If there was a preference for having three games in Sydney over three games in Queensland, there's no way in the world she would agree to that.

"I would love to see a month to six weeks of the [NRL] competition get under way and then get the three games played in reasonable proximity to each other."

Adam Pengilly is a Sports reporter for The Sydney Morning Herald.

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NRL brings in top biochemical and weapons expert for season restart - The Age

UVic donates hand sanitizer – UVic The Ring

Posted on April 14, 2020 by Danzig

University of Victoria chemist David Leitch may be working from his home office, but that doesnt hamper his instinct to pursue scientific discovery to help produce and donate a potential life-saver in the fight against the COVID-19 pandemic.

UVic on Tuesday delivered more than 200 litres of hand sanitizerenough for about 65,000 single dosesfor use by Island Health, whose front-line workers are in the thick of responding to the health crisis.

The ingredients are basic. Its pharmaceutical grade 190 to 200 proof ethanolmuch stronger than the spirits you get at the local liquor storehydrogen peroxide and a softening agent like glycerin to make sure your hands dont get dried out to the point of seriously cracking, says Leitch, who collaborated on the project with six other researchers.

The recipe is in line with World Health Organization guidelinesso its easy, safe, useful and potentially life-saving for someone in this current climate.

The UVic research community is pulling together to address the COVID-19 crisis including digital technologies, biomedical and biochemistry, genome research, proteomics, nursing, law, mathematics, social sciences, exercise science and 3D printing of supplies. To date, there are dozens of UVic research projects linked to the COVID-19 response.

Soap and water continue to be the best bet for hand hygiene. If that is not possible, using a hand sanitizer that is at least 60 per cent alcoholor 120 proofhelps avoid people getting sick or spreading germs, according to the Centers for Disease Control and Prevention.

Leitch, who led the UVic effort, was able to leverage his prior experience in the pharmaceutical industry to plan and execute a manufacturing campaign consistent with stringent Health Canada standards. He recalls discussing with his colleagues the opportunity with simple questions: Its not like we can just whip up a solution and hand it over to a health authority. What is the regulatory process around this, and can we pull this off in time to make a difference?

Researchers used supplies already on hand. From conception, licensing approval to manufacture, the process took less than two weeks, much faster than normal, says Leitch. He adds delivery would not have been possible without extremely rapid turnaround time for Health Canada approvals, a donation of kegs by a local microbrewery to mix the sanitizer and the incredibly hard work of UVic researchers.

UVic chemistry faculty and staffKatherine Elvira, Scott McIndoe, Jeremy Wulff, David Berry, and department chair, Neil Burfordalong with Heather Buckley, cross-appointed in chemistry and civil engineering, spent a recent morning mixing up the solutions.

In uncertain and different times, researchers are also doing everything they can to use their knowledge and experience as teachers to keep the UVic community engaged with science, despite the new remote working reality, says Elvira.

Science contributes vitally to some of the worlds toughest problems including the current COVID-19 response. We are allresearchers, students, UVicadapting as a community, she says. Throughout, we need to ensure we can support our students and their research and their experiences right now.

Burford adds he is inspired by the hard work of faculty, staff and students, and their efforts under these very challenging conditions to maintain consistency. We have to be in touch with our colleagues, our students, checking in often, however we can. I am especially impressed with the resolve of the students as they adapt to the COVID conditions. We will get through this together, says Burford.

In ongoing care for COVID-19 patients, Island Health welcomes donations of personal protective equipment and medical supplies through its website.

Depth Analysis On Automated Biochemical Analyzers Market Size and Study Report 2020 | Beckman Coulter, Hitachi, KHB, Thermo Scientific – Curious Desk

Posted on April 14, 2020 by Danzig

New Report onAutomated Biochemical Analyzers Market size |Research Industry Segment by Applications (Primary Hospital, Prefectural Hospital, Provincial Hospital),by Type (Floor-standing, Bench-top),Regional Outlook, Market Demand, Latest Trends, Automated Biochemical Analyzers Industry Share & Revenue by Manufacturers, Company Profiles, Growth Forecasts 2025.Analyzes current market size and upcoming 5 years growth of this industry.

As per theAutomated Biochemical Analyzers Marketreport, this industry is predicted to grow substantial returns by the end of the forecast duration, recording a profitable yearly growth in the upcoming years. Shedding light on brief of this industry, the report offers considerable details concerning complete valuation of the market as well as detailed analysis of the Automated Biochemical Analyzers Market along with existing growth opportunities in the business vertical.

Download a sample Report of Automated Biochemical Analyzers Market at:http://marketresearchbazaar.com/requestSample/14189

Global Automated Biochemical Analyzers Market is estimated to reach xxx million USD in 2020 and projected to grow at theCAGR of xx% during 2020-2025. According to the latest report the Automated Biochemical Analyzers market has witnessed an unprecedented growth till 2020. The extrapolated future growth isexpected to continue at higher rates by 2025.

Analysis of the major competitors in the market:An outline of the manufacturers active in the Automated Biochemical Analyzers Market, consisting of Beckman CoulterHitachiKHBThermo ScientificDiruiToshibaGaomi CaihongSunostikUritRocheMindray MedicalAbbottSenloTecom ScienceSiemens HealthcareRayt

along with the distribution limits and sales area is reported. Particulars of each competitor including company profile, overview, as well as their range of products is inculcated in the report. The report also gives importance to product sales, price models, gross margins, and revenue generations. The Automated Biochemical Analyzers Market report consists of details such as estimation of the geographical landscape, study related to the market concentration rate as well as concentration ratio over the estimated time period.

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Concepts and ideas in the report:Analysis of the region- based segment in the Automated Biochemical Analyzers Market: As per the report, in terms of provincial scope, the Automated Biochemical Analyzers Market is divided into USA, Europe, Japan, China, India and South East Asia. It also includes particulars related to the products usage throughout the geographical landscape. Data related to the evaluations held by all the zones mentioned as well as the market share registered by each region is included in the report. Sum of all the product consumption growth rate across the applicable regions as well as consumption market share is described in the report. The report speaks about consumption rate of all regions, based on product types and applications.

Some of the Major Highlights of TOC covers:Automated Biochemical Analyzers Regional Market Analysis Automated Biochemical Analyzers Production by Regions Global Automated Biochemical Analyzers Production by Regions Global Automated Biochemical Analyzers Revenue by Regions Automated Biochemical Analyzers Consumption by Regions

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About (Market Research Bazaar):Market Research Bazaar (MRB) a part of VRRB Reports LLP is an overall Market Research and consulting organization. We give unparalleled nature of offering to our clients present all around the world crosswise over industry verticals. Market Research Bazaar has aptitude in giving profound jump showcase understanding alongside advertise knowledge to our clients spread across over different endeavours.

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Depth Analysis On Automated Biochemical Analyzers Market Size and Study Report 2020 | Beckman Coulter, Hitachi, KHB, Thermo Scientific - Curious Desk

PharmaJet partners with Immunomic Therapeutics and EpiVax to develop and deliver COVID-19 Vaccine – BioSpace

Posted on April 14, 2020 by Danzig

GOLDEN, Colo., April 14, 2020 /PRNewswire/ --PharmaJet, the maker of innovative, needle-free injection technology, today announced that its TropisNeedle-free injection system will be used to deliver a COVID-19 vaccine being developed by Immunomic Therapeutics, Inc. (ITI). ITI is a clinical stage biotechnology company pioneering the study of nucleic acid immunotherapy platforms using the body's natural biochemistry to generate a broad immune response. The vaccine candidate against COVID-19 will leverage their investigational UNiversal Intracellular Targeted Expression (UNITETM) platform.

ITI will develop its vaccine in collaboration with EpiVax and PharmaJet, Inc. They aim to deliver a scalable approach that could be applied prophylactically and therapeutically, while being safe and immunogenic. PharmaJet's well established Tropis Needle-free Injection System has been chosen because it precisely targets delivery to the intradermal tissue depth.

Chris Cappello, President and CEO, PharmaJet, Inc., said, "We are pleased to be working with ITI and EpiVax to provide our delivery system for the development of a vaccine to fight COVID-19. Additionally, PharmaJet has been actively working with U.S. federal agencies such as BARDA and the Department of Defense on their global pandemic programs. The Tropis system is already being used to eradicate diseases, such as polio, and has proven very effective in mass immunization campaigns."

According to the Centers for Disease Control (CDC) the 201920 coronavirus pandemic is a pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).There is currently no vaccine to protect against COVID-19.

For more information about PharmaJet visit http://www.pharmajet.com.

View the joint press release here.

Refer to Instructions for Use to ensure safe injections and to review risks.

About PharmaJetPharmaJet's mission is worldwide acceptance of PharmaJet needle-free injection systems as a standard of care in the vaccine delivery market. The PharmaJet Needle-free systems are safe, fast and easy-to-use. They eliminate needlestick injuries, needle reuse and cross contamination, and help reduce sharps waste disposal.

CONTACT:Nancy LillieNancy.Lillie@pharmajet.com1-888-900-4321 Option 3

View original content:http://www.prnewswire.com/news-releases/pharmajet-partners-with-immunomic-therapeutics-and-epivax-to-develop-and-deliver-covid-19-vaccine-301039550.html

SOURCE PharmaJet

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PharmaJet partners with Immunomic Therapeutics and EpiVax to develop and deliver COVID-19 Vaccine - BioSpace

Meet Ghanaian scientist Professor Awandare helping us understand the coronavirus – GhanaWeb

Posted on April 14, 2020 by Danzig

General News of Monday, 13 April 2020

Source: mynewsgh.com

Professor Gordon Akanzuwine Awandare

One of the leading Ghanaian scientists helping us understand the novel coronavirus disease is Professor Gordon Akanzuwine Awandare of the School of Biochemistry and the West African Centre for Cell Biology of Infectious Pathogens (WACCBIP) at the University of Ghana.

He, together with other leading scientists at the University of Ghana, has successfully sequenced the genome of the novel coronavirus disease by examining some 15 confirmed cases of the disease in the country.

Prof Awandare has been a leading light in research on many diseases in the country, especially the malaria parasite.

Born in Kandiga in the Kassena Nankana West District of the Upper East Region, Prof Awandare battled with recurring malaria as a child.

Defying all odds to have a good education, he obtained an a Bsc in Biochemistry from the University of Ghana in 1998 and an MSc in the same field in 2002 before obtaining his PhD in the area in 2007 from the University of Pittsburgh in the United States of America. His area of interest was the malaria parasite, inspired partly by his battle with the disease as a child.

Driven by patriotism, he returned to Ghana after spending three years in America contributing to knowledge there.

Prof Awandare took extraordinary steps to set up his own research group notwithstanding the lack of funds and other bottlenecks.

His major breakthrough came in 2013 when he led a consortium that secured funds to set up a new state of the art centre in the country to research into infectious pathogens. The consortium secured some $8 million from the World Bank, and Prof Awandare became the founding director of the West African Centre for Cell Biology of Infectious Pathogens (WACCBIP) in 2013.

The Centre cutting edge research has ensured that it has secured several other funding to undertake research into many diseases.

He has received many awards for his excellence on research.

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Meet Ghanaian scientist Professor Awandare helping us understand the coronavirus - GhanaWeb

Futurist Transhuman News Blog

Monthly Archives: April 2020

Albright College Fashion and Chemistry Faculty Connect to Make Fabric Face Masks – bctv.org

JMU Chemistry department uses chemicals left in the building to make hand sanitizer – WHSV

Is there a My Chemical Romance nod in this twenty one pilots video? – Alternative Press

What Exactly Is an At Home Chemical Peel, And Which One Is Right for Me? – Yahoo Lifestyle

COVID-19 linked to neurological symptoms, analysis finds – Clinical Daily News – McKnight’s Long Term Care News

Acute Neurologic Deficit Linked to Salicylate Toxicity – MPR – Monthly Prescribing Reference

A third of COVID-19 patients have neurological problems – The Dubrovnik Times

Telemedicine Market demand to reach USD 175 Bn by 2026: Global Market Insights, Inc. – GlobeNewswire

Does Long-Term Exposure to Air Pollution Lead to a Steeper Rate of Cognitive Decline? – Newswise

Global Pediatric Neurology Devices Market- Industry Analysis and Forecast (2020-2027) by Product Type, Service, Neurological Subspecialties,…

State accuses Alamo doctor of attempting to assist in C-section while drunk – danvillesanramon.com

Specialty Physicians Weigh in on the State of Practice After COVID-19 – Rheumatology Network

Informative Report On Interventional Neurology Devices Market 2020 With keyplayer Abbott, DePuy Synthes, Medtronic, Stryker, Terumo, Acandis, Bayer,…

Large-scale analysis links glucose metabolism proteins in the brain to Alzheimer’s disease biology – National Institute on Aging

Lead the way, Kansas | Gaz – Emporia Gazette

NRL brings in top biochemical and weapons expert for season restart – The Age

UVic donates hand sanitizer – UVic The Ring

Depth Analysis On Automated Biochemical Analyzers Market Size and Study Report 2020 | Beckman Coulter, Hitachi, KHB, Thermo Scientific – Curious Desk

PharmaJet partners with Immunomic Therapeutics and EpiVax to develop and deliver COVID-19 Vaccine – BioSpace

Meet Ghanaian scientist Professor Awandare helping us understand the coronavirus – GhanaWeb