Smart microneedle insulin patch could make it easier to treat diabetes – Digital Trends

Close to 10% of the U.S. population, around 30.3 million people, have diabetes. A new treatment delivery system created by bioengineers at the University of North Carolina and theUniversity of California, Los Angeles could help make life easier for them via a smart insulin patch thats about the size of a quarter. All a patient would need to use it would be to slap on a new patch at the start of the day, after which it would monitor and manage glucose levels for the next 24 hours.

It is smart and simple, which means it could help enhance the health and quality of life for people with diabetes, Zhen Gu, the study leader and a professor of bioengineering at the UCLA Samueli School of Engineering, told Digital Trends. It is a smart glucose-responsive insulin release device because it can respond to high blood sugar levels and release only the necessary insulin dosage, thus reducing the risk of hypoglycemia. This is a small and disposable device, so it is very simple and convenient to use; one can remove the patch any time to stop the administration of insulin.

The glucose-monitoring adhesive patch is covered in tiny microneedles, each one less than a millimeter in length. They are made from a glucose-sensing polymer and come pre-loaded with insulin. When the patch is applied, the microneedles penetrate the skin and start measuring blood sugar levels. If the glucose levels increase, the polymer triggers the release of insulin. At the point at which levels return to normal, the patchs insulin delivery also slows down. While this approach still involves pricking the patient with a needle, these needles are much smaller than regular needles. As a result, the patch is less painful than an ordinary injection.

So far, the patch has been successful in studies involving pigs. The researchers were able to use it to successfully control the glucose levels in these animals, which had Type I diabetes, for around 20 hours. Next, the researchers are hoping to progress to further trials, with the goal of commercializing their technology.

This patch has already been accepted by FDAs emerging technology programs for clinical trial applications, Gu said.

A paper describing the research was recently published in the journal Nature Biomedical Engineering.

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Advancing an oral drug for pulmonary arterial hypertension – Penn: Office of University Communications

In pulmonary arterial hypertension (PAH), high blood pressure in the lungs arteries causes the heart to work extra hard to pump blood to the lungs and around the rest of the body. The condition is rare but deadly, and current treatments are expensive and have side effects and inconvenient modes of delivery. There is no cure.

With a goal of developing a more effective, convenient, and affordable therapy, research led by Henry Daniell of Penns School of Dental Medicine produced a protein drug in lettuce leaves to treat PAH. He worked with other scientists, including Steven M. Kawut of Penns Perelman School of Medicine; Tim Lahm from the Indiana University School of Medicine; Maria Arolfo and Hanna Ng of the Stanford Research Institute, on toxicology and pharmacokinetic studies; and Cindy McClintock and Diana Severynse-Stevens of RTI International, on regulatory studies.

The protein drug, composed of the enzyme angiotensin converting enzyme-2 (ACE2) and its protein product angiotensin (1-7), can be taken orally and, in an animal model of PAH, reduced pulmonary artery pressure and remodeling. In addition, rigorous toxicology and dose-response studies suggested the drugs safety in animals. Further work will be necessary to develop this novel treatment approach for patients with PAH. The teams findings appear in the March issue of the journal Biomaterials.

We completed extensive investigations to highly express these proteins in lettuce plants and to ensure the product is safe and effective, says Daniell. Were ready to progress with further work to move this to the clinic.

Daniell has employed his innovative platform to grow biomedically important proteins of many kinds in the leaves of plants. The system works by physically bombarding plant tissue with the genes of interest, prompting chloroplasts into taking up genes and then stably expressing that protein. Propagating those plants then creates a kind of pharmaceutical farm from which the researchers can harvest, dry, and process the leaves, resulting in a powder that can be placed in a capsule or suspended in a liquid for use as an oral medication.

A 2014 publication in the journal Hypertension, on which the current study was based, earned Daniell a prize from the American Heart Association, and support from the National Institutes of Health through its Science Moving TowArds Research Translation and Therapy (SMARTT) program, which aims to efficiently translate promising basic science discoveries into therapies that can make a difference in peoples lives.

That earlier publication had shown that ACE2 and angiotensin (1-7) could be expressed in tobacco leaves and, when fed to rats with a condition that models pulmonary arterial hypertension, could significantly reduce the animals pulmonary artery pressure while also improving cardiac function.

To create a drug that humans could safely ingest, however, required moving from a tobacco to a lettuce-based platform. The new work takes advantage of other advancements the Daniell lab has made during the last several years. He and colleagues have successfully devised methods to enhance expression of human genes in the plants and to remove the antibiotic resistance gene that is used to select for angiotensin-producing plants. Theyve also worked with a partner to produce genetically engineered plants in a production facility that adheres to FDA standards.

In the current work, the researchers demonstrated that they could accurately evaluate the dose of the ACE2 and angiotensin (1-7) proteins in lettuce, and that the products could be dried and kept shelf stable for as long as two years.

Funding from the SMARTT program enabled animal studies evaluating toxicology, pharmacodynamic, and pharmacokinetic studies, which evaluate the safety of the drug, where it goes in the body, and how long it persists in the body at different doses, in work done at Stanford University.

And to confirm that the lettuce formulation of the product had a positive impact on experimental PAH, the team fed rats a solution containing the drug for four weeks. Their lung pressures went down 30-50%, and the structure of their arteries also improved.

This is an innovative approach to targeting the renin-angiotensin-aldosterone system in pulmonary arterial hypertension, says Penn Medicines Kawut, which may hold promise in this and other diseases.

We are very excited about this work that shows efficacy of bioencapsulated ACE2 and angiotensin (1-7) in our animal model of pulmonary arterial hypertension, says Indiana Universitys Lahm. We now need to confirm that the intervention also works in other animal models and when given later in the disease. Ultimately, our goal is to move this to the clinic for trials in patients, but we need to make sure we learn as much as possible from animal studies and from studies in healthy human subjects to make sure this intervention is safe and efficacious in patients.

In other future work, Daniell hopes to continue evaluating the effects of ACE2 and angiotensin (1-7) in treating different types of cardiovascular disease, such as heart failure.

There are some potentially broad applications of this drug that were hoping to investigate, says Daniell.

Daniell, Kawut, and Lahms coauthors on the paper were Penn Dental Medicines Venkata Mangu, Jiyoung Park, Peyman Habibi, Yao Shi, and Patricia A. Gonnella; and Indiana Universitys Bakhtiyor Yakubov, Amanda Fisher, Todd Cook, and Lily Zeng.

Henry Daniell is vice chair and W.D. Miller Professor in the Department of Basic & Translational Sciences in the University of Pennsylvania School of Dental Medicine.

Steven M. Kawut is professor of medicine and director of the Pulmonary Vascular Disease Program at the University of Pennsylvania Perelman School of Medicine.

Funding for the study came from the National Institutes of Health (NIH) (grants HL107904, HL109442, and HL133191) and through the NIHs Science Moving TowArds Research Translation and Therapy (SMARTT) program (contracts HHSN268201600011C and HHSN268201600014C).

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Advancing an oral drug for pulmonary arterial hypertension - Penn: Office of University Communications

ASCO GU 2020: Niraparib in Patients with mCRPC and Biallelic DNA-Repair Gene Defects: Correlative Measures of Tumor Response in Phase II GALAHAD Study…

San Francisco, California (UroToday.com)Approximately 50% of patients with metastatic castration-resistant prostate cancer (mCRPC) cannot be assessed for a response using RECIST 1.1 criteria and there is a need to develop a dynamic endpoint that provides an early indication of clinical benefit. Circulating tumor cells (CTCs) are easily accessible, reflect tumor biology, and could be a marker of anti-tumor activity beyond PSA and conventional imaging. CTC0 and CTC conversion to <5 CTCs/7.5 mL blood may occur very early on treatment and were highly correlated with OS across 5 large phase III trials of mCRPC therapies in a recent landmark paper by Heller et al.1 Niraparib, a highly potent and selective poly (ADP-ribose) polymerase (PARP) inhibitor received breakthrough designation by US FDA for treatment of patients withBRCA1,2mutant mCRPC who progressed on taxane and androgen receptor-targeted therapy. CTC detection associates with poor outcomes, with declining counts consistent with improved survival. At todays prostate cancer session at GU ASCO 2020, Matthew Smith presented results of their CTC correlative data assessing CTC0 as an endpoint in mCRPC.

The GALAHAD study assessed niraparib (300 mg daily) in patients with mCRPC plus DRD. Patients with non-measurable soft tissue disease by RECIST 1.1 were required to have a baseline CTC count 1 cell/7.5 mL blood. CTC response was defined as CTC conversion to <5 for patients with baseline CTC5 and CTC drop to 0 post-baseline for patients with 1 baseline CTC.

There were 204 patients included in this study. For the primary efficacy population of patients withBRCA1/2mutations, the objective response rate (ORR) by RECIST 1.1 criteria was 41.4%. CTC response rates for this population were as high as ORR regardless of measurability:

CTC0 and CTC conversion were early indicators of response and are associated with longer time on therapy in patients with measurable and non-measurable disease. Furthermore, CTC0 and CTC conversion are associated with longer OS:

Additionally, CTC0 was associated with improved rPFS in the overall population, and CTC0 and CTC conversion were also associated with PSA reduction among these BRCA patients.

Dr. Smith concluded with several take home messages:

Clinical trial information:NCT02854436

Presented by: Matthew R. Smith, MD, Ph.D., Professor of Medicine, Harvard Medical School, Assistant in Medicine, Hematology/Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Written by: Zachary Klaassen, MD, MSc Assistant Professor of Urology, Georgia Cancer Center, Augusta University/Medical College of Georgia Twitter: @zklaassen_mdat the 2020 Genitourinary Cancers Symposium, ASCO GU#GU20, February 13-15, 2020, San Francisco, California

References:

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Mexico City Medical Congress to Showcase the Global Stem Cells Group’s Latest Innovations – PRUnderground

The Global Stem Cells Group (GSCG) is set to sponsor the XI Congreso Mundial de Medicina Antienvejecimiento y Longevidad (World Conference of Anti-Aging and Longevity Medicine) to be held in Mexico City, Mexico on February 16-18, 2020.

The medical congress is expected to attract over 450 physicians and researchers from across the world interested in anti-aging and longevity practices and medical innovations. Over 30 speakers are slated to share information with attendees on a wide range of topics on how to lead a long, healthy life and improve longevity.

The GSCG is set to share a number of its latest innovations with congress attendees, including its newly released GCell technology device. This cutting-edge tool utilizes micrograft technology to harness the natural and powerful restorative capabilities of adipose tissues. Because it is FDA compliant, the device allows physicians across the globe to continue practicing adult stem cells-based procedures.

Additional benefits of GCell technology include shorter treatment times, delivering in-office treatments in around 30 minutes with local anesthesia, as well as less fat collection compared to existing treatments (15 mL versus 50 mL). GCell technology holds exciting implications across a range of medical specialties, including orthopedics, dermatology, cosmetic gynecology, aesthetics, and hair loss.

In addition to its GCell technology, the GSCG will also feature its newest line of stem cells products derived from first-tissue exosomes. Cellgenic Flow Exosomes utilizes the latest science and research available in cellular therapies to deliver a non-surgical approach to creating regenerative responses in a broad range of treatments. The product utilizes exosomes, which replicate the signals given out by stem cells, versus actual stem cells. Exosomes play a pivotal role in cell-to-cell communication and are involved in a wide range of physiological processes. These particles transfer critical bioactive molecules such as proteins, mRNA, and miRNA between cells and regulate gene expression in recipient cells.

The XI Congreso Mundial de Medicina Antienvejecimiento y Longevidad is one of the worlds premier events connecting physicians and researchers with todays most innovative treatments and technologies utilizing regenerative medicine, said Benito Novas, CEO of the GSCG. As a worldwide leader in training, education, and innovative products in the field of regenerative medicine, the GSCG is pleased to sponsor this congress and share its exciting new portfolio of products with physicians from across the world.

To learn more about the Global Stem Cells Group and all of the groups latest news and innovations, visit http://www.stemcellsgroup.com/

About Global Stem Cells Group

Global Stem Cells Group (GSCG) is a worldwide network that combines seven major medical corporations, each focused on furthering scientific and technological advancements to lead cutting-edge stem cell development, treatments, and training. The united efforts of GSCGs affiliate companies provide medical practitioners with a one-stop hub for stem cell solutions that adhere to the highest medical standards.

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Mexico City Medical Congress to Showcase the Global Stem Cells Group's Latest Innovations - PRUnderground

Durst Organization sees flurry of new business at 1 WTC – Real Estate Weekly

The Durst Organization and The Port Authority of New York and New Jersey announced a half dozen new leases at One World Trade Center.

DADA Holdings LLC has signed a five-year lease for 4,786 s/f on the 71st floor; Princeton Longevity Center signed a 10-year lease for 11,075 s/f on the 71st floor. This will be both DADA and Princeton Longevitys first offices in New York City.

Ichnos Science Inc., moving its offices to New York City from Paramus, New Jersey, signed a seven-year and five-month lease for 10,847 s/f on the 76th floor.

Pison Stream Solutions signed a three-year lease for 10,804 s/f on the 49th floor of OWTC, making the building their global headquarters.

Also signed were two expansion deals. Symphony Communications Services has signed a one-year lease for 3,510 s/f on the 45th floor, bringing their total square footage on the floor to 12,100 s/f.

Additionally, Augustus Intelligence signed a five-year lease for 6,475 s/f on the 77th floor of OWTC, doubling their footprint with a move from the 45th floor.

We are extremely pleased with the leasing activity at One World Trade Center, said Jonathan (Jody) Durst, President of The Durst Organization.

We are beginning the year by welcoming our newest tenants DADA Holdings, Ichnos, Princeton Longevity and Pison and celebrating the success of Symphony and Augustus with their office expansions at One WTC.

Princeton Longevity Center was represented by Steven Rotter, Blake Goodman and Justin Haber of JLL.

Ichnos Sciences was represented by Cushman & Wakefields Drew Braver and Mark Zaziski.

Michael Thomas and Aidan Campbell of Colliers represented Pison. Symphony Communications Services was represented by Christopher Foerch of Savills.

And Augustus was represented by Carol Engel of CS Engel and Associates. The landlord was represented by Senior Managing Director Eric Engelhardt and Managing Director Karen Kuznick of The Durst Organization and the Newmark Knight Frank team of David Falk, Jason Greenstein, Peter Shimkin, Hal Stein and Travis Wilson.

Augustus Intelligence builds artificial intelligence products and secure infrastructure services to help enterprise clients reinvent themselves.

Pison Stream Solutions is a global leader in the research and development of chemical coatings platforms for niche markets. They implement their systems across defense, aerospace, automotive, antimicrobial, renewable energy applications, and additive platforms.

Princeton Longevity Center is a next-generation medical facility combining the most advanced technology with an integrated and individually tailored Preventive Medicine program.

A fully integrated, global biotechnology company with the spirit of a start-up, Ichnos Sciences is shifting the way the world thinks about innovation in medicine through its research and development of transformative, disease-centric treatments in oncology, autoimmune disease and pain.

The company, with headquarters in Paramus, N.J., is rapidly advancing a clinical-stage pipeline of novel, first-in-class candidates designed to address complex diseases and treat patients holistically.

With a patented BEAT technology platform along with pioneering teams in Switzerland and India, Ichnos Sciences has a mission to provide breakthrough, curative therapies that will hopefully extend and improve lives, writing a new chapter in healthcare.

Symphony offers a secure team collaboration platform that transforms the way users communicate effectively and securely with a single workflow application.

Symphony was founded in October 2014 and is headquartered in Palo Alto, CA, with offices in Hong Kong, London, New York, Paris, Singapore, Sophia-Antipolis, Stockholm and Tokyo.

One World Trade Center is the tallest building in the Western Hemisphere and home to the largest community of media and tech innovators.

The 3.1 million-square-foot LEED Gold Certified skyscraper features premier office space and some of the most spectacular views in the world.

On the 64th floor, One World Commons offers 25,000 s/f of tenant amenities including a world-class business and social hub fostering workplace creativity, collaboration, and community.

Built by The Port Authority of New York and New Jersey and The Durst Organization in a unique public-private partnership, The Durst Organization is responsible for marketing, leasing, and managing the property.

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How to live longer: Find time in your year to do this to extend your lifespan – Express

Life expectancy graphs provide much cause for optimism in 2020, especially if you trace it back to when records first began. The steep rise in global life expectancy over the last few decades paints a particularly pleasing picture. The upward trend can in part be attributed to pioneering research in the field of science and medicine, which continues to add further weight to universally accepted truths, such as the importance of eating a healthy, balanced diet to stave off the risk of developing life-threatening complications.

Another truism that has been supported by rigorous research is that going on holiday is good for your health.

According to a 40-year study published in the The Journal of Nutrition, Health & Aging, vacationing can extend your lifespan.

To support this hypothesis, researchers analysed data on 1,222 middle-aged male executives born in 1919 to 1934 and recruited into the Helsinki Businessmen Study in 1974 and 1975.

Participants had at least one risk factor for cardiovascular disease (smoking, high blood pressure, high cholesterol, elevated triglycerides, glucose intolerance, overweight).

READ MORE:Best supplements for heart health: Four supplements to ensure a healthy heart

Participants were randomised into a control group (610 men) or an intervention group (612 men) for five years.

The intervention group received oral and written advice every four months to do aerobic physical activity, eat a healthy diet, achieve a healthy weight, and stop smoking.

When health advice alone was not effective, men in the intervention group also received drugs recommended at that time to lower blood pressure (beta-blockers and diuretics) and lipids (clofibrate and probucol).

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Men in the control group received usual healthcare and were not seen by the investigators. As previously reported, the risk of cardiovascular disease was reduced by 46 percent in the intervention group compared to the control group by the end of the trial. However, at the 15-year follow-up in 1989 there had been more deaths in the intervention group than in the control group. The surprising finding prompted the researchers to do some deeper digging, which revealed that shorter vacations were associated with excess deaths in the intervention group.

In the intervention group, men who took three weeks or less annual vacation had a 37 percent greater chance of dying in 1974 to 2004 than those who took more than three weeks.

Accounting for the findings, Professor Timo Strandberg, of the University of Helsinki, Finland, said: "The harm caused by the intensive lifestyle regime was concentrated in a subgroup of men with shorter yearly vacation time.

In our study, men with shorter vacations worked more and slept less than those who took longer vacations.

He continued: This stressful lifestyle may have overruled any benefit of the intervention. We think the intervention itself may also have had an adverse psychological effect on these men by adding stress to their lives."

Professor Strandberg concluded: "Our results do not indicate that health education is harmful. Rather, they suggest that stress reduction is an essential part of programmes aimed at reducing the risk of cardiovascular disease.

Lifestyle advice should be wisely combined with modern drug treatment to prevent cardiovascular events in high-risk individuals."

According to the American Heart Association, stress may affect behaviours and factors that increase heart disease risk, such as high blood pressure, cholesterol levels, smoking, physical inactivity and overeating.

Some people may choose to drink too much alcohol or smoke cigarettes to manage their chronic stress, however these habits can increase blood pressure and may damage artery walls, it adds.

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How to live longer: Find time in your year to do this to extend your lifespan - Express

What ‘dry fasting’ is and why you shouldn’t do it – Los Angeles Times

A new fad diet making the rounds on wellness influencer Instagram wont actually help you lose weight. And it could cause dehydration, urinary tract infections, kidney stones, organ failure even death.

Its called dry fasting. It goes beyond what most of us would consider fasting abstaining from solid food or liquid calories and requires consuming no water or liquids of any kind for many hours or even days at a time.

Instagram and other social media sites have provided a glossy new platform for extremely dubious health and nutrition claims. Posts about dry fasting often tout the need to heal or rest or reset your kidneys, or boost their filtration. In practice, what dry fasting will do is make you look a bit more toned, because your body is using up the water in your cells for energy.

Even more dubious claims suggest that dry fasting forces your body to burn toxins, or fat, or inflammation, or tumors. It does not. When you stop feeding your body calories, it breaks down muscle and fat. The toxic byproducts of that breakdown process build up in your system, requiring extra hydration to flush them out.

In other words, if youre abstaining from food, your body needs more water, not less.

Experts agree: There is no dietary or nutritional reason to go on a dry fast.

I dont recommend it at all, said Dr. Pauline Yi, a physician at UCLA Health Beverly Hills who regularly treats patients in their late teens and early 20s. She said intermittent fasting and other fasting-type diets are a popular topic with patients, and she has no problem with people trying them out.

But I also tell them when youre fasting you have to drink water, she said. You cannot go without hydration.

The majority of the human body is water. Your individual water consumption needs depend on your height, weight, health and the climate, but generally speaking, Yi said people should be consuming at least 68 ounces almost nine cups of water every day.

Cary Kreutzer, an associate professor at USCs schools of gerontology and medicine whose area of expertise includes nutrition and diet, says digestive systems arent meant to have extended breaks. She likened making your kidneys go without water to letting your cars engine run out of oil. You can basically burn out some parts of the car that youre going to have to get replaced, she said. You dont want those replacement parts to include your vital organs.

Another unintended consequence of dry fasting: It sets your body in water-conservation mode.

Your body likes homeostasis, said Yi, the physician. If youre going to cut back on water, your body will produce hormones and chemicals to hold onto any water.

So while you might gain a very short-term benefit by looking a tiny bit more toned while youre severely dehydrated (body-builders have been known to dry fast before competitions for that reason), once you consume liquid again, your body rebounds and desperately hangs on to even more water than before. Its like yo-yo dieting in fast motion.

Dry fasting is not the same thing as intermittent fasting, which has become a popular fad diet in recent years. There are different variations of intermittent fasting, but most people start with 16 hours of fasting followed by eight hours of eating. Martin Berkhan created the LeanGains 16:8 intermittent fasting guide and is widely credited with popularizing the diet. On his website, leangains.com, Berkhan writes that during the 16-hour fasting window, coffee, calorie-free sweeteners, diet soda, sugar-free gum and up to a teaspoon of milk in a cup of coffee wont break the fast.

The subreddit for fasting, r/fasting, has an Introduction to Intermittent Fasting guide that contains the following tips for surviving the fasting portion of your day:

Valter Longo has studied starvation, fasting and calorie restriction in humans for nearly 30 years. Hes currently the director of the Longevity Institute at USC and a professor of gerontology. He developed the Fasting-Mimicking Diet, or FMD, a fasting-type diet with small prepackaged meals intended to provide the health and longevity benefits of a five-day fast without requiring a doctors supervision. Fasting-type diets have grown in popularity in recent years for a simple reason, he said: Because they work.

But he said hes not aware of any reputable studies about the effects of dry fasting, and said he wouldnt even consider putting one together, also for a simple reason: Its incredibly dangerous.

For sure, the body needs to reset, but there are safe ways of doing that, and dry fasting is not one of them, Longo said. We require water.

His work has also involved looking at how cultures and religions have engaged with starvation and fasting throughout human history, and says he hasnt heard of any that involved extended fasting without water. The closest is Ramadan, during which observers go without food or water during daylight hours but at most, that lasts for 16 hours, and its preceded and followed by extensive hydration.

If someone tries dry fasting for a full day, Longo said, they risk side effects like developing kidney stones. Longer than that, and you start risking your life.

Some proponents of dry fasting eschew water but recommend hydrating with fresh fruits and vegetables. Hydrating with fruit is certainly better than not hydrating at all. An orange has about a half-cup of water in it; to get to the recommended 68 ounces of water a day, youd have to eat around 17 oranges. Thats a lot of peeling.

So, in conclusion: Dry fasting puts you at risk of kidney stones or organ failure. There are no known, proven long-term benefits to doing it. Though different types of fasts and fasting diets can be beneficial, there is no medical evidence to suggest you need to stop consuming water for any period of time, or that water from fruit is better for you than filtered drinking water. Do not take medical advice from a photo of a person in a sarong.

Please drink some water.

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What 'dry fasting' is and why you shouldn't do it - Los Angeles Times

How to live longer: A handful of this tasty treats proven to increase life expectancy – Express

Increasing the number of years we have on this earth is a dream of many, with numerous studies and research on the topic. Respecting our bodies for the miracles they are is key to a longer and healthier life. Advanced research is unravelling the mystery of how to add years to ones life and the results may surprise many. When it comes to snacking, one particular food item has come up tops for being delicious, healthy and help a person reduce their risk of heart disease and cancers.

Nuts are not only delicious but they should be added into everyday life for a proven anti-ageing diet which helps ward off chronic diseases like cardiovascular disease, diabetes and certain cancers.

Nuts have been a regular component of the human diet for thousands of years.

A growing body of evidence has found that nuts are healthy and through scientific data its been found that eating nuts each day may reduce the risk of heart disease.

More recent research has found that eating nuts is linked to a lower risk of colon cancer, gallbladder disease and diverticulitis, along with lower rates of some disease markers like inflammation, insulin resistance, metabolic syndrome and even visceral fat.

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A study which was published in the New England Journal of Medicine in 2013 found strong evidence that nuts of all kinds can help one to live longer.

The research noted that eating just an ounce of nuts daily was linked to a 20 percent lower risk of death over a 30-year period.

Additionally, a 2015 paper published in JAMA Internal Medicine involved more than 200,000 people in the US and China and also found that eating nuts can improve life longevity.

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Dr Frank Hu, professor of nutrition and epidemiology at the Harvard School of Public Health said: We found that people who ate nuts every day lived longer, healthier lives than people who didnt eat nuts.

Dr Penny Kris-Etherton, a professor of medicine at the University of Pennsylvania added: Eating nuts lowers LDL cholesterol and raises HDL cholesterol and also lowers blood pressure and blood pressure responses to stress.

"Nut consumption helps boost a process called reverse cholesterol transport, by which HDL particles in the blood sweep away fatty plaque from clogged arteries.

In a study with the US National Library of Medicine National Institutes of Health, frequent nut eaters and how it affects their mortality rate was investigated.

The study involved 7,216 men and women aged 55 to 80.

Nut consumption was assessed at baseline and mortality was ascertained by medical records.

The study concluded that increased frequency of nut consumption was associated with a significantly reduced risk of mortality in a Mediterranean population at high cardiovascular risk.

Some people worry they will gain weight if they eat nuts, but surprisingly, the bodyweight of people who regularly eat nuts has not been shown to be higher than that of non-nut eaters, according to a 2008 article in The Journal of Nutrition.

This is true despite the fact that calories consumed by regular nut eaters total an average of 250 more calories per day than that of people who don't eat any nuts.

Nuts are rich in protein, antioxidants and beneficial plant compounds.

Whats more, theyre a great source of vitamins and minerals such as copper, magnesium, potassium, folate, niacin and vitamin B6 and E.

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How to live longer: A handful of this tasty treats proven to increase life expectancy - Express

The health benefits of falling and staying in love – Telegraph.co.uk

All you need is love; love is just a game for two; we found love in a hopeless place is there anything that could be written about love that hasn't already been sung in the Top 40s chart?

Well, how about the health benefits of love? Generally, singers prefer songs about getting stronger after a break-up, but theres plenty of science to show that love and all the things that come with it are better for your health than being alone.

Love has the ability to powerfully influence our physical and mental wellbeing, explains Niels Ek, psychologist and co-founder of mental wellbeing and self-development platform Remente. Humans are typically social creatures and, often, we are strongest, healthiest, and happiest when we feel close to others.

An abundance of studies have found that loneliness negatively impacts our psychological wellbeing; it's associated with a higher probability of anxiety and depression. In contrast, research from the International Journal of Environmental Research and Public Healthsaw a positive correlation between relationships and mental health. Theycan, among other things, boost ones confidence and trust.

So, if you needed one more excuse to make that big romantic gesture this Valentines Day, heres a few bits of evidence to help your case

Well, at least when compared with being with other people. A study published by the American Psychomatic Medicine Society had 120 healthy adults wear blood pressure monitors for a six-day period. The research found that the participants systolic blood pressure was down by one point when they were with their partners, compared to when they were with other people.

This was even the case in participants who didnt describe their relationships as being particularly happy, suggesting familiarity and intimacy with another person is all it takes. Good to remember if your partner forgets your anniversary this year

As part of an attempt to promote marriage as a concept by George Bushs government, the US Health and Human Services Department reviewed a tonne of studies and found that those in long term relationships tended to visit doctors less and have shorter hospital stays.

It was unknown why this was, but it could be as simple as the idea that having a partner forces you to be healthy, says Ek. The health benefits are partly due to the camaraderie that comes with being involved with another person. A caring partner wants what is best for us and, therefore, tends to ensure that we eat, drink, and sleep as were supposed to, seek healthcare when we need it, and so on.

If youre annoyed at being expected to get a bunch of flowers for your partner on Valentines Day, just remember that youre actually helping yourself by doing so.

Thats according to a study published by the Association For Psychological Science. It starts by citing studies which have shown that higher life satisfaction leads to longevity, then goes on to present evidence showing that your partner having higher life satisfaction might also help boost longevity.

This could be down to the well-documented phenomenon where doing nice things for other people has been found to improve life satisfaction for the person doing the good deeds.

The early stages of a relationship can be stressful. You find yourself panicking about all manner of things: do they like me? Am I coming on too strong? Did I just blow it? Does my hair look good? Are they going to get on with my friends?

However, the evidence shows that after these initial doubts and worries youll generally become more relaxed, less anxious, and happier. A study from Harvard Medical School found that hugging, kissing, and sex with a partner releases a hormone called oxytocin, which deepens feelings of attachment as well as contentment, calmness, and security.

In addition, studies have shown that being around the person you love releases dopamine, the hormone responsible for feelings of happiness, and less release of cortisol, the hormone associated with stress.

Alright, alright, in the world of Tinder you dont need to be in love to have sex, but given the aforementioned study which found that sex with a partner boosts the release of oxytocin, it might be the ideal way of doing so. And doing it is exactly what you should be doing if you want to stay healthy.

A study from Wilkes University in Pennsylvania found that people who had sex once per week were 30pc higher in immunoglobulin A than in those who had no sex at all. And what does immunoglobulin A do? Well, it helps defend the body against illness.

However, its also worth noting that people who had sex more than twice per week were even lower in immunoglobin A than those who had no sex at all. And the study itself even stated that more research was probably needed before we could say definitely.

Originally posted here:
The health benefits of falling and staying in love - Telegraph.co.uk

Dr. Fulton is providing High-Quality Care for His Patients for Over 20 years – BossyNews

Dr. Fulton is providing his patients with high-quality carefor more than 20 years, and he mainly focuses on the Anti-Aging Medicine,Hormone Replacement Therapy for both men & women, Aesthetic Services etc.at the SKINovative situated in the Gilbert of Arizona. Also, he has acquiredmassive experience in assisting and treating his patients with a wide range ofseveral health issues.

Dr. Fulton is very dedicated to providing all his patientswith excellent care. Also, he emphasizes utilizing the most efficient healthtactics to ensure that his patients are in a good position to find solutionsfor their health issues. Besides, he is an expert in several medical fields. Inaddition to this, he is a Diplomate of the American Academy of the Anti-AgingMedicine, along with the American Board of Phlebology and a broad-certified inEmergency Medicine.

He said that he had a passion for searching newer ways toaid people to feel better, and thats what drew him to become a doctor andcontinued to drive him. He also said that his mission was to deliver the bestcare utilizing the most upgraded technology and techniques to provide every clientwith the best possible result.

Since adding Simpatras BHRT and technology services to hispractice, Dr. Fulton has been able to provide his patients with some moreoptions to alleviate their health issues. The addition of SimpatrasTMTechnology suite to his practice has allowed him to go extra miles to make surethat all of his patients are getting the highest quality care.

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Dr. Fulton is providing High-Quality Care for His Patients for Over 20 years - BossyNews

The Red Carpet Skin Workout by Celebrity Facialist Thuyen Nguyen – W Magazine

Photographer: Craig McDeanStylist: Alex White

In Asia, we believe that when it comes to skin care, you must challenge the skin and muscles in order to train them, strengthen them and keep them remaining toned. Westerners do this with their body muscles but often ignore the face.

Thuyen Nguyen, A-list celebrity facialist (Cindy Crawford, Katy Perry, Jennifer Aniston, Michelle Williams and Natalie Portman are clients) has a point. You may be able to recall the last set of strenuous leg lifts you did earlier this week, but when did you last dedicate some time to toning up your jawline with some facial exercises? Many reputable aestheticians have begun incorporating skin massages and facial exercises into their clients treatments, especially in the last few years. Nguyen takes those skin principles and ups the ante a few notches by also implementing the time-honored Eastern traditions of face cupping, with lymphatic drainage as well as his unique set of Vietnamese facial exercises (an estimated 12,000 strokes per skin session) to keep his bevy of clientele pleased. In town for the Oscars (he is performing facials at Dr. Kevin Brenners office in Beverly Hills this weekend exclusively), he spoke with W about the ins and outs of holistic skin care and the importance of an overall routine that promotes good muscle tone.

Facial massages have been on the up; people are noticing the practice maintains skin elasticity and firmness. When did you personally realize the connection?

Early in my career when I was in the medical field, I volunteered massage therapy for paralyzed patients in hospitals. Because of their condition, they required massage therapy on a regular basis to prevent the damage of muscle atrophy and skin deterioration. Within a couple of weeks, I quickly noticed improvements of muscle tone, skin health and elasticity. Thats when I realized massage is also anti-aging.

There are so many avenues of wellness that your background of Eastern medicine can take you. What exactly inspired you to be an aesthetician?

My background helped me realize the disconnect, and ask, why do we use exercise to maintain health, vitality and youthfulness for our bodies, but not for the muscles and skin of the neck and face? So, I started studying more intensely Eastern holistic care and also the cosmetic benefits of massage therapy, then I pioneered it into my signature Skin fitness within skin care approach. Thus healthy, instant results led me to a client list primarily built on word-of-mouth.

How did you get your big break professionally?

My first public platform came when I was scouted to be the creative director of the Greenwich Hotels spa back in 2006, where I debuted my unique body and facial services. My skin-care line Thuyen Skin Care also launched for the first time there, beyond my private practice. Thats when I was first tagged as the well-kept secret of the Greenwich Hotel. From that project, I decided to venture independently to open my own locations in the Hamptons and Tribeca.

You are known for your signature InstaLiftFacial Sculpting Facial. What makes it so impactful?

Like anything in wellness or holistic medicine, our skin requires a combination of multiple parts to deliver a synergistic host of benefits.So, within the InstantLift Sculpting Facial massage session, the face and the necks skin and muscles go through an intense process of lymphatic drainage, detoxing of all three dermal layers, relaxing of muscle fascia tension, rapid cellular regeneration and metabolism, pore decongestion, and improved elasticity of the skin matrix. All this occurs simultaneously while my millipede fingers thoroughly work in multiple layers of myprofessional-grade line of organic elixirs and serums. Manually, my fingers run unusually fast and have been clocked at an average of over 12,000 strokes per session. Thats how I got the nickname The Maestro from beauty editors.

How does aVietnamese Sculpting Massage differ? Is this theFaceXercisethat you perform on your clients?

FaceXercise is my skin fitness philosophy and features my signature InstantLift Sculpting Facial, which originated from my Vietnamese roots. The significant difference with the Vietnamese approach to professional skin care is that a rigorous facial massage is the main featurewhich is more holistically beneficial and cosmetically enhancing than the slower-paced, lighter-pressure facial massages typical of Western facials that rely more on pampering and product application.

At what point during the facial is the lymphaticdrainage incorporatedinto the massage?

The first part of the 60-minute InstantLift Facial process is a thorough drainage of the lymphatic system which is basically our garbage disposer carrying an excess fluid made up of white blood cells, bacteria and cellular waste. This is such an important functioning system of our body and skin that is parallel to our circulatory system. However, it relies on exercise and daily muscle movements to maintain our health and immunity.

How does cupping benefit the complexion? I am curious, doesnt one risk any acnecoming to the surfaceafterfacecupping since cupping is known to remove toxins?

Like back cupping in acupuncture, facial cupping is a preventative modality that is over 3000 years old, with proven benefits. The difference is when I do facial cupping, I have an application method that does not yield post-treatment cupping marks.Remember, detoxing is definitely a secondary benefit to utilizing it to manually exercise and tighten the pores with the various cup sizes while alternating with sculpting massage. Its rare that acne occurs since the alternating repetitions of lymphatic drainage and massage helps alleviate inflammation.One has a better chance of inflaming acne through invasive pore extractions or low-quality skin products, or even volatile foods. In fact, Ive done this facial on clients a few hours before the red carpet, and its calmed down inflamed cystic acne spots. Facial cupping, if done correctly, also prevents breakouts and recurring blackheads with regular facial maintenance.

How long do the resultsof your facial usually last?

With first-time clients, a facial session yields a more fresh, brighter and healthy glowing complexion fora couple of weeks.Like any exercise, the health and cosmetic benefits will build on top of the previous facial workout.Most of my devoted clients have been with me for years and view this as a necessary part of their fitness and healthy lifestyle so they tend to reflect clear, age-defying complexions at any age and find themselves relying on less makeup to cover flaws.

Does this help pigmentation in any way?

Absolutely.Hyperpigmentation is sometimes rooted in our immune system, which is why discoloration appears more as we age or even when someone is pregnant.Since the massage therapy raises our endorphins and boosts our immune system, this facial helps keep hyperpigmentation at bay and even enhances our skins natural ability to protect itself from harsher environmental factors.

Are you a fan of lasers and peels?

I am pretty organic and holistically inclined in my approach. But I also believe in moderation when it comes to cosmetic lasers or non-invasive peels.Building the skin from the internal to external is my best advice.

Lets discuss your workwithclients that will be walking down the red carpet on Sunday. While every person's skin is unique, whats the rule of thumb for facials before a big event? Do you recommend that your clients get a facial the day before, or the day of,a special event?

Keep in mind that most of my clients are devoted regulars so I have clients coming weekly, every other week to once a month minimum. However, with clients that have special events, public appearances or important photoshoots, they reserve me on the day directly before hair and makeup. Thats actually how my name got passed around the red carpet scene during awards season. Makeup artists like Angela Levin, (who Jennifer Aniston introduced me to eight years ago,) Hung Vanngo (we both work with Katy Perry, Cindy Crawford and Uma Thurman, who originally introduced us) witnessed my work on various clients's skin and generously referred me to others.My skin work helps make their work easier by ridding clients of puffiness and bringing out their sculpted cheekbones with an overall well-rested look.

In your professional opinion, what would be an ideal product to apply before makeup to keep the skin glowing in anticipation of foundation and the layers of makeup that go on?

I would say my Thuyen Skin Care Multivitamin Nourishing Serum massaged into freshly cleansed skin. It quickly revives with organic skin nutrients. Then, follow with theWrinkle & Frown Line Cream.Its a non-greasy skin barrier and a supple skin palette to apply makeup over while still protecting the skin during hours of hot lights and cameras.

Do youhave any particular advice for clients in terms of what to do to their skin or what to avoidthe evening beforeared carpet event, or any special event?

Often red carpet clients arrange to see me one or two days before the important event, then the day-of, since they come in town for more than one appearance and the first is usually to reset their complexion from the stresses and bloating of flying, or a hectic schedule of filming. I do encourage them to stock up on green organic juices and anti-inflammatory foods.But even if they dont have the time or discipline in social settings, I have miraculously delivered to many in a panicI can help them look like they slept for a week.

What skin productscan you not live without?

Honestly, I keep my skin regime simple. I get a body massage regularly and massage my face and neck rigorously daily for a minute while showering. Of course, I use my own results-proven line, but am adamant that without the internal workout, one cannot truly reach their skin goals with just topical.However, with this marathon of L.A. awards, my Hydrating & Tightening Travel Whip has been my secret, TSA-friendly travel companion on those flights.

Any skin supplements you think really help skin glow?

Im an avid organic green juicer, so for me its all about raw, live vitamins and minerals gained from fresh vegetables and fruits paired with a tablespoon of apple cider vinegar and a whole lemon to alkaline.That daily dose gives me so much energy to last me throughout the day and helps keep the liver cleansed, which in turns shows in a clearer, brighter complexion. Also, I love and swear by the Skin, Hair & Nail Repair Supplement from Pure Essentials. I especially recommend it to my clients, since they are always on the go.

What advice can you give our readers specifically in terms of prepping their skin at home for a night out?

Beyond a healthier meal program with daily green juicea few days beforeevent, I encourage my clients to get their facial passive exercise game on at least the night before any special event.Any minute or more of a daily self-facial massage you can give yourself is a must addition to your skin regimen, between your professional facial massage sessions. I guarantee you that its a fantastic booster when you need a quick recharge to look your best.Everyone has some sense of massage, so I guide clients to not try to be me and focus less on choreographing the massage, but rather rub vigorously the skin of their neck and face in all directions while finishing with upward strokes.The skin is a reactive organ, so the more you manually knead it, the more blood will surface to your dermal layers to deliver nutrients from your foods while removing toxins through your lymphatic system.And lastly, skin care is half psychology. Always view yourself kindly with positive thoughtsthose good vibes with proper rest will help you glow inside and out.

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The Red Carpet Skin Workout by Celebrity Facialist Thuyen Nguyen - W Magazine

Michael Bloombergs Anti-Trump Superhero Cosplay Will Only Go So FarRight? – Yahoo Lifestyle

From Esquire

Michael Bloomberg's plan was to parachute into the 2020 Democratic primary on Super Tuesday, ignoring Iowa and New Hampshire and the traditional Momentum Model that has dominated American political narratives for decades to focus on delegate-rich states like California and Texas. Like any sensible paratrooper, he hoped the ground would be softened up for him a bit with a $350-million ad blitz before he jumped out of the plane. Except events of the last week have forced him to crash-land into the primary conversation early, even as he blankets Instagram with an astroturfed campaign across the biggest meme-aggregation (read: meme-thieving) accounts. All together now, folks: FuckJerry!

You see, people keep posting tape of Bloomberg being racist. There was the clip where he essentially discussed black men between the ages of 16 and 25 as a criminal class. This was not just in defense of his stop-and-frisk policies as New York mayor, but of a more general policing regime where you flood black and brown neighborhoods with cops and lock people up on minor offenses like marijuana possession. A CNN person reacted to this by questioning the motives of the person who dug the clip up, despite the fact it's been on YouTube for years.

Then someone posted tape of Bloomberg suggesting that getting rid of redlininga policy wherein black Americans were denied the opportunity to buy homes in middle-class neighborhoods, a pillar of building wealth and getting a decent education in Americawas somehow responsible for the 2008 housing crisis and the resulting global financial meltdown. That's right: it's not Bloomberg's Wall Street buddies or the firms to which he sold Bloomberg terminals who are to blame, even if they engaged in reckless behavior and created an incentive structure that rewarded risky lending. It's the people who fought against racial discrimination in housing!

This is particularly gross considering the Great Recession decimated black wealth, in part because banks targeted black homeowners with predatory lending practices, to the point that the average white household now has 10 times the wealth of the average black household. That's worse than in 2007.

All this should serve to remind people that Bloomberg is essentially just a wealthy Republican in the mold of, say, Mitt Romney. He's disgusted by Trump's personal conduct, and by his inaction on the climate crisis and gun violence. (Romney, in fairness, doesn't give a shit about climate change. Bloomberg's record on that front is strong.) But Bloomberg basically thinks the system as presently constructed is working, that it is delivering fair and just results for our society, that the powerful people within it are nearly always right and deserve to be where they are, and that the powerless are where they are because of their personal failings. Also, as mayor of New York City, he had something of an authoritarian streak.

Photo credit: Brett Carlsen - Getty Images

Bloomberg would almost certainly be a better president than the current one, if only because he seems to have full access to his cognitive faculties and is not a two-bit grifter with shady financial connections that sprawl across the multinational underworld. (Full disclosure: I once interned in the mayor's office in 2012, while Bloomberg was mayor. I primarily worked on updating spreadsheets keeping track of the fire hydrants on Randall's Island. City government!) He's also receiving all this highly justified scrutiny because he has gained some serious ground in the polls. He's up to 14 percent nationally in the RealClearPolitics polling average, behind only Bernie Sanders and Joe Biden. He may take a hit after this week's attention, particularly because he's actually been attracting quite a few black voters from Biden's faltering campaign. Then again, he's also getting plenty of endorsements from black Democratic leaders.

Bloomberg's rise is rooted in his astroturf strategy, a campaign which seems to exist only in the commercial blocs between television programming segments and in the corniest precincts of social media. In the latter case, part of his strategy seems to be to bait Donald Trump into personal back-and-forths, so that America can get what it truly deserves: two alleged New York billionairesonly Bloomberg's status is truly assured in that departmentarguing about their comparative heights, intelligence, and facial complexion in order to determine who should run the country. Thursday brought Exhibit Aor maybe J.

There's reason to believe that this strategy might just pay off for Bloomberg. First of all, people buy astroturf. It's like grass, but you don't have to water it! With Bloomberg, people might feel they won't have to pay attention to politics all the time anymore, which could appeal to professional-class coastal liberals who, like Bloomberg himself, generally like the economic status quo and are tired of being mad. (This impulse is understandable and also a huge part of why American democracy is in severe decay.) There is also reason to believe that a segment of the Democratic base is hungry for an Anti-Trump Superhero to do battle with the president on top of the Empire State Building or whatever. As our tangerine generalissimo has himself shown, the aesthetics of personal combat are powerful in American politics, if only because it feels like someone's doing the fighting for you.

For a while, the anti-Trump Resistance adopted Special Counsel Robert Mueller as their avatar, putting full and unflinching faith in the aging lawman to bring down a lawless scoundrel at high noon. It was approaching a messiah-complex situation, and even featured cartoon caricatures of the 74-year-old that, in the vein of the pro-Trump stuff, depicted him as a buff hyper-patriotic warrior. (You might call this Krassenstein's Monster.) Then Mueller bowed before a Justice Department rule against indicting the president, outlining obstruction-of-justice charges without calling them that, and he then testified before Congress in a performance that failed to produce the TV spectacle required to move the needle on anything in America. Meanwhile, the increasing sprawl of Trump's activities in West Asia, combined with the treachery of Mueller's eventual boss in Attorney General William Barr, raises questions about whether he really got to the bottom of what happened.

Photo credit: Brett Carlsen - Getty Images

Similarly, when Trump swept to power with a fully Republican Congress in 2016, there was no institutional bulwark against his renegade behavior except the free press. Democratic leadership in the House and Senate appeared particularly weak. And so we should have seen it coming when a brash, tough-talking young lawyer came on the scene representing a thorn in the Trumpian sideStephanie Clifford, d.b.a. Stormy Danielsand made himself into a Resistance Hero. Michael Avenatti was "everything Chuck Schumer and Nancy Pelosi and the Democrats were not: aesthetically combative; dismissive of the when-they-go-low-we-go-high mentality of the previous election; and a budding rival to Donald Trump in his sheer ability to garner publicity." Or at least, that's what I wrote when the news broke that Avenatti had been arrested on a string of federal charges, including those related to an alleged attempted shakedown of Nike.

Back in the glorious present day, Bloomberg is positioning himself as the Anti-Trump Candidate now that Biden is really starting to slip. Unlike Bernie Sanders or Elizabeth Warren or even fellow billionaire Tom Steyer, he is not running on the basis that much of anything outside the Oval Office is broken in this country. Only Amy Klobuchar has anything resembling his singular focus on Trump, and getting rid of El Jefe is the number-one concern for Democratic voters. It could work, particularly because Bloomberg is unlikely to meet the same fate as either of those onetime Anti-Trump Superheroes. He is not a gutter-brawling grifter in the Avenatti mold, and he seems a little more lively than Mueller did in those congressional hearings in which he so reluctantly participated.

He also has more money than God, and can keep the firehose of ads going regardless of how much negative coverage he gets in the press. This, of course, raises the question of whether Bloomberg merely represents a different kind of threat to American democracy than does Trump, who openly denies any legitimate power outside his own. If American oligarchs exist, Bloomberg is one. Certainly, he's a plutocrat. And he seems decently well-positioned to skip along the gold-brick road all the way to Oz, a state of affairs which would lead the Democratic Party towards Rockefeller Republicanism. Then the choice for the electorate would be between that and the modern Republican Party's reactionary ethno-nationalism. Where's your money on what working-class folks would choose four years later?

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Michael Bloombergs Anti-Trump Superhero Cosplay Will Only Go So FarRight? - Yahoo Lifestyle

The Very Predictable Results Of Cutting Planned Parenthood Funding – Yahoo Lifestyle

Many of us saw this coming. Because, frankly, its common sense. When you take away programs that educate, protect, and provide healthcare for millions of Americans who may not receive that education, protection, or healthcare otherwise, the repercussions arent going to be good.

Yet, in the name of Christianity? Protecting tax dollars? Morals? Values? And, of course, saving lives, the relentless campaign against Planned Parenthood continues and has effectively shut down many of their valuable health centers around the country.

Health centers that staunch pro-lifers work tirelessly to defund, despite the fact that they provide the following per year:

birth control for nearly two million people

over 4.2 million STD tests and treatments

over 320,000 breast exams

nearly 295,000 Pap tests

Ironic, isnt it? Hypocritical even? Because what does birth control prevent? Unwanted or unplanned pregnancies. What do STD tests and treatments prevent and treat? Harmful or potential fatal diseases. What do breast exams and Pap tests detect? Cancer that will need medical intervention to save lives.

Hmmm.

So here were are, in 2020, still fighting with stubborn anti-abortion activists over the same basic points: Planned Parenthood does far more than provide abortion services. In fact, many of the shuttered clinics around the nation were not even ones that performed the procedure at all. What they were doing, however, before having their doors closed was reducing and preventing abortions by offering education, protection, and birth control, among other health services.

Finallyand this ones a real sticking pointabortions have taken place since the dawn of mankind. And they will still continue to take place. Defunding Planned Parenthood will not stop them. They will only make them less safe. And, as statistics are now showing, removing programs like those offered by Planned Parenthood actually increases the rates of teen pregnancies. Guess what option many teens will turn to when faced with an unwanted pregnancy? You guessed it.

Round and round we go.

Lets look at the state of Texas, for example. Prior to 2011, the teen birth rate in Texas had fallen by an impressive 44% between 1988 and 2011. But that year former Texas Governor Rick Perry slashed the family planning budget by 67% (from $111 million to $37.9) during which 82 clinics were closed statewide (none of which performed abortions, by the way). And in the years that followed, interestingly but not surprisingly, the teen birth rate went back up.

In a state that already has a high percentage of abstinence-only sex ed and, as an equally depressing alternative, no sexual education at all, closing Planned Parenthood clinics is just another door shut in the face of young women who need it. Its just another way for conservative Americans to cross their arms and turn away, refusing to acknowledge that like it or not, girls and young women have sex. They always have. They always will. And they need education, protection, birth control, and health care.

Another disastrous effect seen in Texas isthat pregnancy-related deaths doubled after the state stopped reimbursing Planned Parenthood and imposed drastic funding cuts for womens health. Hows that for being pro-life?

On the other hand, lets look at Colorado, where the Susan Thompson Buffett Foundation gave the state $23 million over six years to provide free or low-cost contraception to low-income women. The results were telling. The teen birth rate dropped 40% from 2009 to 2013, while the teen abortion rate fell 42%. And the abortion rate for all women fell 34%.

Thats one of the many valuable things Planned Parenthood does for womenprovides them with contraception so they can prevent unwanted pregnancies, continue with their education, and make their own choice of if and when theyd like to become mothers.

But you know what? This is far more than a debate about abortion. Because the truth is, Planned Parenthood is often the only healthcare option for women in this country, and if PP health centers cant provide care for them, nobody will. In fact, in more than 20% of the counties where Planned Parenthood health centers operate, there are no other health care providers who serve patients who rely on safety-net providers. The bottom line is that so many women and girls have nowhere else to go.

Family planning clinics are a lifeline for many low-income and rural women. Four in ten women who go to family planning centers describe the clinics as their only source of medical care, a USA Today article reports.

Four in ten.

How again are we making America great when we defund and force clinics to permanently close their doors, causing girls and young women around the nation to be less safe and at a greater risk of harm, illness, or death because their safety net is gone?

Also, another common retort those against Planned Parenthood use is that other healthcare providers can and will absorb Planned Parenthoods patients. Heres why thats false and frankly a dangerous mindset to have. As explained on I Stand With Planned Parenthood, Providers of ob-gyn care who accept Medicaid, such as Planned Parenthood, are in particularly short supply. In addition, Planned Parenthood health centers are more likely than other safety-net family planning providers to provide the full range of birth control (including IUDs and implants) on-site and more likely to offer rapid-result HIV testing. Even The American Public Health Association says its ludicrousfor politicians to claim that other providers could simply absorb Planned Parenthoods patients.

Its not just about birth control and pregnancies either. An article in USA Today reported that among the five health centers closed in Indiana, one was in rural Scott County, which also happens to be the epicenter of the worst HIV outbreak in the states history.

Treating those infected in the epidemic will cost more than $100 million, according to the Centers for Disease Control and Prevention, the USA Today reports. Like many PP clinics, the one in Scott County provided HIV testing and referrals to care in an area with a shortage of doctors and limited medical resources. Now its gone.

Side note: like the other Indiana health centers that have shut down, this clinic also did not perform abortions.

Thats what is happening here. So many resources and much-needed aid are being stripped away from Americans in need, all in the name of a hot-button political issue. At the end of the day, the nationwide defunding and barrage of attacks on Planned Parenthood is hurting America, not making it great.

Heres where we are on a national scale. According to the Guttmacher Institute, in 2013, publicly funded family planning services like those Planned Parenthood provides helped women prevent two million unintended pregnancies and 693,000 abortions. Without these valuable services, rates of unintended pregnancies, unplanned births, and abortions would have been 60% higher, the research says.

And over the last few years, however, more and more family planning budgets have been slashed. Clinics and health centers have been closed. What do you think is going to happen to these numbers if we continue to strip Americans in need of vital medical care?

So again, what does it really mean to be pro-life?

See the original article on ScaryMommy.com

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The Very Predictable Results Of Cutting Planned Parenthood Funding - Yahoo Lifestyle

I Created a Vision Board For Life Outside of Motherhood to Help Me Regain My Identity – Yahoo Lifestyle

In August of 2017 I brought my first little human into the world and left my job at an ad agency to pursue my lifelong dream of raising a family. I spent my days cleaning, playing, and teaching, and my nights gushing over the adorable pictures and videos I'd taken throughout the day and reading up on every developmental milestone, parenting hack, and how-to the internet could possibly muster. Then I started to notice myself slipping away. I loved my son so much that it was easy to pour every ounce of energy and spare second into him, but I owed it to my family and myself to regain a sense of individuality and identity that had once been an integral part of my life, and I knew exactly where to start.

During my stint in ad agency life, my team and I spent time brainstorming the best ways to build brands from the ground up. We'd often rely on the construction of a vision board to keep us focused on what we wanted a brand to feel like, look like, and sound like. These vision boards became crucial reference points as we moved along in the process in making sure each decision was aligned with our end goal. So I kicked off my hunt to regain my sense of identity by creating a vision board of my own.

I started by creating some overarching categories to act as a guide for filling out my board, like intellectual, physical, spiritual, professional, and social areas of development. Then, under each category, I listed off some of my existing hobbies and interests like politics, sports, and my religion. I was dusting off and recommitting to engaging these parts of me that had been dormant for what felt like an eternity, and it was liberating.

Related: I May Be a Mom - but I'm Also So Much More

There's More to Me Than Being a Mom

I loved looking back at the many parts of me that once existed, but I wanted to direct my focus to the future. I've always wanted to learn to fix cars, take up woodworking, and speak a second language, so onto the list they went. My blood starts pumping when I think about learning to kickbox, and I want to focus more time on developing professionally, so those two made the cut. As the wheels of who I wanted to become outside of motherhood started turning, so did my confidence that I could accomplish even more in and outside of the home.

The next step was to transform all of these thoughts and ideas into an eye catching and inspiring vision board. I found pictures to symbolize each list item, printed them off, cut them out, and Mod Podged them to a foam board that now sits on the desk in the corner of my room. It's not the most professional piece of art I've ever taken in, but few artistic expressions have struck me to my core quite like my vision board.

Each time I catch a glimpse of my board, it breathes life into what can feel like mundane days and weeks, and reminds me that my hopes and dreams for personal development and my dedication to motherhood don't have to be mutually exclusive. I can be an engaged and devoted mother who woodworks, kickboxes, and speaks Arabic. If every spare second I have doesn't go to my kids' needs, I haven't failed. I've shown my kids what it means to develop and accomplish. I've shown them that investing time in themselves isn't selfish, it's necessary, even when they become parents.

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I Created a Vision Board For Life Outside of Motherhood to Help Me Regain My Identity - Yahoo Lifestyle

Kering Turned Over $17.15 Billion in 2019 – Yahoo Lifestyle

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Fashion is now big business. And Kering is cashing into the tune of $17.15 billion.

That gargantuan sum is the figure the luxury groupowner of Gucci, Saint Laurent and Bottega Venetaturned over in 2019. The majority of that number$10.42 billion to be exactwas generated by Gucci alone, despite the emergence of the deadly coronavirus at the end of the year. As a whole, the groups margins surpassed the 30 percent mark for the first time.

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In a statement, Kering CEO Franois-Henri Pinault acknowledged the deadly viruswhich, as of press time, had claimed 1370 lives and infected more than 64,000 peopleand pledged to support the the Chinese people.

In the difficult period that China is going through, we would like to express once again our support for all our collaborators and our solidarity with the Chinese people, Pinault said. The particularly uncertain environment that prevails at the present time does not, however, call into question the fundamentals of Kering on the luxury market.

Kering is one of several companies in the fashion industry to donate to relief efforts related to the deadly disease. China and the surrounding territories play a key role in Kerings long-term growth strategy, so its no surprise the CEO would tout the conglomerates financial security as the virus roils markets.

As for the other houses under the Kering umbrella, a full breakdown of each labels earnings was not provided. The companys report, however, revealed that growth varied among its brands. Bottega Veneta, for instance, appears to have grown the least amongst the brands disclosed, only inching up 2.2 percent year on year. That news comes as something of a surprise given new creative director Daniel Lees viral approach to promoting the brand.

As for Kerings future trajectory, that may depend on how fast the coronavirus is contained. The company has temporarily closed half of its stores in China for an undetermined amount of time. Given that China accounts for more than a third of luxury sales worldwide, its safe to say that the luxury group is anxiously awaiting a resolution.

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Kering Turned Over $17.15 Billion in 2019 - Yahoo Lifestyle

Global Medical Wellness Market 2020, by Manufactures, Application, Trends, Growth, Demand and Forecast to 2025 – Import Tourism

According to this study, over the next five years the Medical Wellness market will register a XX.XX% CAGR in terms of revenue, the global market size will reach US$ xx million by 2025, from US$ xx million in 2019. In particular, this report presents the global market share (sales and revenue) of key companies in Medical Wellness business, shared in Chapter 3.

This report presents a comprehensive overview, market shares, and growth opportunities of Medical Wellness market by product type, application, key manufacturers and key regions and countries.

Request a sample report here: https://www.orbisresearch.com/contacts/request-sample/4219323

This study considers the Medical Wellness value and volume generated from the sales of the following segments:

Segmentation by product type: breakdown data from 2014 to 2019, in Section 2.3; and forecast to 2025

Complementary and Alternative MedicineBeauty Care and Anti-AgingPreventative & Personalized Medicine and Public HealthHealthy Eating, Nutrition & Weight LossRejuvenationOther

Segmentation by application: breakdown data from 2014 to 2019, in Section 2.4; and forecast to 2025

FranchiseCompany Owned Outlets

This report also splits the market by region: Breakdown data in Chapter 4, 5, 6, 7 and 8.

AmericasUnited StatesCanadaMexicoBrazilAPACChinaJapanKoreaSoutheast AsiaIndiaAustraliaEuropeGermanyFranceUKItalyRussiaSpainMiddle East & AfricaEgyptSouth AfricaIsraelTurkeyGCC Countries

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The report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the market. The key manufacturers covered in this report: Breakdown data in in Chapter 3.

Massage EnvyHEALING HOTELS OF THE WORLDSteiner Leisure LimitedFitness WorldUniversal CompaniesWorld GymNanjing ZhaohuiBeauty FarmEdge Systems LLCVLCC Wellness CenterArashiyu Japanese Foot SpaWTS InternationalEnrich Hair & SkinGolds Gym InternationalThe Body HolidayKaya Skin ClinicGuardian LifecareKayco VividBon VitalBiologique RechercheHealthkart

In addition, this report discusses the key drivers influencing market growth, opportunities, the challenges and the risks faced by key manufacturers and the market as a whole. It also analyzes key emerging trends and their impact on present and future development.

Research objectives

To study and analyze the global Medical Wellness consumption (value & volume) by key regions/countries, product type and application, history data from 2014 to 2018, and forecast to 2025.

To understand the structure of Medical Wellness market by identifying its various subsegments.

Focuses on the key global Medical Wellness manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.

To analyze the Medical Wellness with respect to individual growth trends, future prospects, and their contribution to the total market.

To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).

To project the consumption of Medical Wellness submarkets, with respect to key regions (along with their respective key countries).

To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.

To strategically profile the key players and comprehensively analyze their growth strategies.

Table of Contents

1 Scope of the Report1.1 Market Introduction1.2 Research Objectives1.3 Years Considered1.4 Market Research Methodology1.5 Economic Indicators1.6 Currency ConsideredContinued

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Global Medical Wellness Market 2020, by Manufactures, Application, Trends, Growth, Demand and Forecast to 2025 - Import Tourism

Kate Middleton and Prince William Step Out for a Rare Appearance With Prince Charles and Camilla – Yahoo Lifestyle

From Town & Country

Prince Charles and Camilla and Prince William and Kate arrived for a rare joint engagement today, where they will be visiting a rehabilitation center for members of the armed forces. The foursome pulled up in two cars at the Defence Medical Rehabilitation Centre in Loughborough just before midday to meet staff and patients.

Despite heavy hail before they arrived, the weather brightened in time for the royals to walk from their cars to the 300 million center.

Photo credit: Joe Giddens - PA Images - Getty Images

While all four royals have busy timetables of official engagements, it is rare to see a joint trip, and the visit reflects the importance of supporting servicemen and women to the royal family. It also offers a look at the monarchys future, with the two couples now holding the fort when it comes to duties supporting the Queen. With Prince Philip retired, Prince Andrew stepping back, and Prince Harry and Meghan forging their own path, the number of family members carrying out engagements has significantly fallen.

But those in the direct line of succession have demonstrated they are carrying on as usual, with several visits already announced for both couples for the next few weeks.

Photo credit: Joe Giddens - PA Images - Getty Images

Today they were welcomed by Captain Alison Hofman QARNNS, Commanding Officer of the Defence Medical Rehabilitation Centre (DMRC) and taken on a tour of the site.

They were due to visit some of the therapy areas and observe patients undertaking gym rehabilitation sessions. A stop at the prosthetics workshop to hear from patients and staff about the services available was also planned. A reception for staff and patients and the unveiling a plaque will conclude the visit.

The new 300 million Defence Medical Rehabilitation Centre, known as DMRC Stanford Hall, is operated by the Ministry of Defence and began admitting patients in October 2018. It took over from Headley Court in Surrey as the main rehabilitation center for the armed forces.

Prince William was patron of the charity raising money for the new center, and said at the handover: "I have seen the growth of an idea transfer into what we see today, and it is a rare and immensely satisfying thing to have witnessed.

The DNRC initiative stemmed from the 6th Duke of Westminsters idea to support servicemen. Gerald Grosvenor initiated a founding gift of 70 million. Following his death in 2016, his son Hugh and the Grosvenor family have carried forward his idea and the familys overall gift now stands at 105 million.

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Kate Middleton and Prince William Step Out for a Rare Appearance With Prince Charles and Camilla - Yahoo Lifestyle

Rosie Huntington-Whiteleys Thong Toe Sandals Are The Unlikely Hero of Her Ensemble – Yahoo Lifestyle

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Rosie Huntington Whiteleys on-trend ensemble for the Byredo store opening event last night deserves some special attention. For the occasion in Los Angeles on Feb. 13, the 32-year-old model was spotted wearing a minimalist, sharply tailored Bottega Venetta chocolate brown suit. The blazer had a deep V-neckline and a narrow belt that cinched at the waist. On the bottom, her trousers has a relaxed-fit silhouette, mimicking a jogger-style pant, especially when cuffed by the ankle straps of her sandals.

Rosie Huntington-Whiteley and Kate Bosworth Byredo Store Opening, Inside, Los Angeles, USA - 13 Feb 2020 Wearing Bottega Veneta

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Speaking of, Whiteley opted to finish off the look with one of the most controversial and trendiest shoe styles of the moment: the high-heeled thong sandal. The model is wearing the Bottega Veneta Spiral Sandals in chocolate. The Italian-made shoe has a single diagonal strap over foot, as well as a toe ring. Together this achieves the thong look. The aforementioned ankle straps coil around the leg like a snake.

This sighting confirms that Whiteley continues to be among the avid wearers of this celebrity-beloved trend. Recently, the multi-hyphenate was spotted in another Bottega Veneta version of the silhouette twice: first in the white colorway while in Los Angeles and then again in the brown iteration of the same style in New York City.

Joining Whiteley, actress Kate Bosworth also chose to wear a more minimalist ensemble for the event. She styled an oversized white dress and a pair of short black heels, featuring silver crystal embellishment. Suited for the occasion, Bosworth accessorized the look with a Byredo handbag. The closed-toe pumps offer a similar aesthetic to this Gianvito Rossi crystal-embellished sandals that Whiteley wore a few weeks ago for the Hourglass launch party in London.

From these chic ensembles, these two shoe trends show no signs of slowing down for the season ahead.

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Rosie Huntington-Whiteleys Thong Toe Sandals Are The Unlikely Hero of Her Ensemble - Yahoo Lifestyle

Princess Diana’s 1989 Trip to New York Will Appear in The Crown Season 4 – Yahoo Lifestyle

From Town & Country

Princess Diana is set to travel quite a bit in the next season of The Crown. Back in October, actors Josh O'Connor and Emma Corrin were seen restaging Prince Charles and Princess Diana's 1983 royal tour of Australia, and now, paparazzi have spotted Corrin filming another iconic royal tripthis time, Diana's 1989 solo visit to New York.

Corrin was photographed on set in Manchester, England, which had been done up to look like the streets of New York. She was wearing what appeared to be a recreation of Diana's white Victor Edelstein gown, which the royal wore to a charity gala at the Brooklyn Academy Of Music.

Photo credit: Splash News

The Crown also recreated another one of Diana's stops in New York: a visit to the Henry Street Settlement. According to the Manchester Evening News, a building in Manchester's Northern Quarter was modified to approximate the look of the Settlement.

Corrin was photographed in another costume, filming what was believed to be another New York scene. While her plaid skirt suit didn't quite resemble the clothing Princess Diana actually wore during her other stops in New Yorkthat would be a purple and black suitthe look does feel like something that Diana would've worn.

Photo credit: Splash News

Diana's three-day visit to New York is certainly deserving of some air time on The Crown. The Princess made waves when she visited the Henry Street Settlement and AIDS patients at a Harlem hospitaland of course, she made quite an impact at that gala.

Fans can look forward to seeing the show's take on these historical events when The Crown's fourth season debuts, likely later this year.

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Princess Diana's 1989 Trip to New York Will Appear in The Crown Season 4 - Yahoo Lifestyle

Charlize Theron Wore This Controversial Shoe on the Red Carpet – Yahoo Lifestyle

After what seemed like a marathon of awards shows, red carpets, luncheons, and after-parties, Charlize Theron probably wanted to put her feet up, not slip into another pair of sky-high heels for an event. And while she didn't skip out on a Los Angeles event celebrating the launch of Birkenstock's 1774 collection, she did choose to slide into a pair of the brand's comfortable, decidedly down-to-earth designs. Does this mean that the crunchy sandals are officially red carpet-worthy? If Theron thinks so, it's only a matter of time.

Stewart Cook/WWD/Shutterstock

RELATED: Charlize Theron's "Worst Date" Story Is So Awkward That It Sounds Fictional

It went down at an event celebrating Argentinian artist Amalia Ulman at Frieze Los Angeles, where Theron wore a pair of white Birks with thick, crisscross straps. According to British Vogue, it's the new Siena style, which features "elevated" materials and tone-on-tone hardware. It may seem surprising to see Theron, who marched through awards season wearing couture Givenchy, Christian Dior, and Celine heels, in something so seemingly normal, but the event, which Birkenstock hosted in collaboration with Matchesfashion.com, most likely called for some support (which Birkenstocks are known for).

Theron also chose to skip out on the couture, pairing her sandals with wide-leg white pants and a Dior "Revolution" sweater, so while it was decidedly casual, it didn't eschew her penchant for donning Dior at events, whether they're big or small.

And even though they're not ceramicists or professors at liberal arts colleges, celebrities love Birks. Reese Witherspoon has evangelized her shearling-lined pair and everyone from Miranda Kerr to the Olsen twins have been spotted wearing them during their off-duty hours. While they're still a rarity on the red carpet, Theron's proving that they're certainly not just for farmers' market runs.

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Charlize Theron Wore This Controversial Shoe on the Red Carpet - Yahoo Lifestyle