Study tests whether stem cells heal arthritis in large dogs – Los Angeles Times

About a year ago, Cheryl Timmons was worried her dog Baxter would soon need to retire from being a therapy dog due to arthritis in his hips.

The 99-pound German shepherds physical health was wearing down after years of bringing joy to childrens hospitals, senior homes and courtrooms, where he served as the first and only service dog providing comfort to child trafficking victims in Orange County.

Timmons, who rescued Baxter from the streets of San Bernardino, worried that she may even have to put him down.

To combat the worsening arthritis, Timmons took him to therapy sessions. A GoFundMe campaign to help pay for the therapy reached a goal of $4,500.

But the arthritis was still taking hold, affecting how Baxter functioned during long workdays.

Then in late August, he was given stem cell injections as part of a new study at the Anaheim Hills Pet Clinic. The effort, headed by San Diego-based Animal Cell Therapies, is testing whether stem cells can help alleviate arthritis in dogs weighing 70 pounds or more.

Baxter, now 11 years old, has been feeling better since he received his injection.

His arthritis is greatly improved, Timmons said. I swear by the stem cell treatment. It has made such a huge difference.

Everybody in the court would notice that he wasnt having a good day. Now hes looking great again. Hes running through the courtroom. He is one happy boy.

Baxter was one of about 10 dogs that was tested at the Anaheim clinic. Animal Cell Therapies is conducting the testing at a dozen clinics throughout the country.

There are about 35 dogs currently enrolled in the study. Researchers are hoping to test between 60 and 80 dogs.

Kathy Petrucci, chief executive of Animal Cell Therapies, said its too early to tell whether the treatment is successful in treating arthritis in large dogs, but the early results are promising.

The company conducted a similar study a year ago, which showed benefits for arthritis in dogs under 70 pounds. However, the results were mixed for bigger dogs.

Petrucci said they increased the dosage for the current study.

We dont know every single mechanism that is involved ... it helps decrease inflammation in the joints, Petrucci said of the treatment. We think that the cells secrete a lot of positive beneficial growth factors that help decrease inflammation, help make the environment a better, more friendly place for more normal cells to come in and help repair the joints.

Whatever the cause, Timmons just hopes the treatment allows Baxter to keep doing what he does best.

With the stem cells, he acts like hes invincible, Timmons said, laughing. I really hope he is.

To enroll in the study, visit dogstemcellstudy.com.

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Study tests whether stem cells heal arthritis in large dogs - Los Angeles Times

Canine Stem Cell Therapy Market Regulations and Competitive Landscape Outlook to 2029 – Instant Tech News

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Stem Cell Therapy Market 2020 Company Profiles, Trends by Types and Application, Operating Business Segments 2026 – News Parents

New Jersey, United States, This report looks at the global market Stem Cell Therapy Status and future trends, focusing on the global market major enterprises, while the current and future trends in North America, Europe, China, Asia Pacific and South America and other regions.

Global Stem Cell TherapyMarketwas valued at USD 86.62 million in 2016 and is projected to reach USD 221.03million by 2025, growing at a CAGR of 10.97% from 2017 to 2025.

This article focuses on the market size, market share, market positioning, product type and development planning of enterprises with important roles in the global Market.

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In the segmentation section of the report, the authors have elaborately presented key driving factors for different segments of the global Stem Cell Therapy industry. The report offers a Complete research study on product type and application segments of the global Stem Cell Therapy industry. The segmental analysis provided in the report is expected to help players and investors to identify lucrative growth pockets of the global Stem Cell Therapy industry.

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TAGS: Stem Cell Therapy Market Size, Stem Cell Therapy Market Growth, Stem Cell Therapy Market Forecast, Stem Cell Therapy Market Analysis, Stem Cell Therapy Market Trends, Stem Cell Therapy Market

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Stem Cell Therapy Market 2020 Company Profiles, Trends by Types and Application, Operating Business Segments 2026 - News Parents

DDP and Austin Aries Reportedly Pitching Stem Cell Venture to AEW – 411mania.com

Diamond Dallas Page and Austin Aries had business at last nights AEW according to a new report, but not the kind you might immediately think of. As noted last night, DDP and Aries were seen entering the area at last nights episode in Atlanta.

According to BodySlam.net, the two were there because theyre part of a stem cell treatment venture. They were there to pitch the idea to AEW in hopes that the company would buy into the venture. Stem Cell therapy has become increasingly popular among wrestlers to deal with injury issues over the past several years, and Aries is one of several people (along with Ken Shamrock, Rob Van Dam and others) to make regular mention of the BioXcellerator stem cell therapy clinic.

DDP has been a semi-regular on AEW, making several appearances on Dynamite over the past few months.

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DDP and Austin Aries Reportedly Pitching Stem Cell Venture to AEW - 411mania.com

High-throughput screening reveals new compound to maintain lung health – Drug Target Review

Researchers have screened 20,000 molecules to discover a potent compound with low toxicity that restores the balance of healthy stem cells in the lungs of mice.

A molecule identified by researchers through screening helps maintain a healthy balance of cells in airway and lung tissue. According to the scientists, if the compound, so far only studied in isolated human and mouse cells, has the same effect in people, it may lead to new drugs to treat or prevent lung cancer.

We think this could help us develop a new therapy that promotes airway health, said Dr Brigitte Gomperts, lead author of the study and professor of paediatrics and pulmonary medicine at the University of California LA (UCLA), US, where the stiudy was conducted. This could not only inform the treatment of lung cancer, but help prevent its progression in the first place.

The human respiratory system is regularly replenished with healthy cells. That process is driven by airway basal stem cells, which divide to produce both more stem cells and the mucociliary cells that line the airways and lungs.

Mucociliary cells include:

In healthy lungs, airway basal stem cells stay balanced between producing mucociliary cells and self-renewing to maintain a population of stem cells.In pre-cancerous cells in the lungs, basal stem cells divide more often than usual, generating a large number of stem cells but too few mucociliary cells. The resulting imbalance of cells in the airway leaves it unable to properly clear debris and creates a greater risk that the pre-cancerous cells will develop into a tumour.

In the new study, the researchers analysed airway cells from equal numbers of biopsies of healthy people, patients with pre-malignant lung cancer lesions and patients with squamous lung cancer. They discovered that one group of molecules collectively called the Wnt/beta-catenin signaling pathway was present at different levels in the basal stem cells of the patient samples versus the cells from healthy people.

Normal airway tissue, left and lung cancer tissue, right, with an overabundance of basal stem cells (green). The activated form of beta-catenin (red) in the lung cancer can be targeted by the Wnt Inhibitor Compound 1 (credit: Broad Stem Cell Research Center).

Altering the levels of these molecules in healthy airway cells from mice, the team found the balance between stem cells and mucociliary cells shifted, mimicking the imbalance seen in lung pre-cancers.

When you activate the Wnt/beta-catenin signaling pathway, these stem cells just divide and divide, said Gomperts.

Finally, the researchers screened more than 20,000 chemical compounds using high-throughput methods. They investigated their ability to reverse this effect in human cells, lowering levels of Wnt and restoring the balance of stem cells and mature airway cells.

One compound, named as Wnt Inhibitor Compound 1 (WIC1), was particularly effective at limiting the proliferation of basal stem cells and restoring the balance of the stem cells and mucociliary cells to regular levels. The researchers also noted that the compound was less toxic to airway cells than previously discovered molecules that block Wnt/beta-catenin signalling.

The identification of this new drug is a nice tool to tease apart the biology of the Wnt/beta-catenin signalling pathway and its effects on lung health, said Cody Aros, the first author of the new paper and a UCLA graduate student. Its also very exciting that it may act in a new way than other existing Wnt/beta-catenin signalling pathway inhibitors and has such low toxicity.

As WIC1 was identified through a random drug screen, the researchers do not yet know exactly how it works, but they are planning future studies on its mechanism and safety.

The study was published in Cell Reports.

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High-throughput screening reveals new compound to maintain lung health - Drug Target Review

Locking in and preserving your healthy stem cells has never been easier and more accessible as Acorn Biolabs partners with Coverdale Clinics. – Yahoo…

Appointments for stem cell & DNA collection now available.

TORONTO , Feb. 20, 2020 /CNW/ - With the rapid emergence of regenerative medicine therapies and genetic analysis testing reaching mainstream medicine, consumers are demanding increased opportunities to prepare for their future healthcare needs, including banking a viable source of cells to preserve their current health.

Acorn Biolabs (CNW Group/Acorn Biolabs)

To meet this growing demand, Acorn Biolabs, the leading non-invasive stem cell collection, cryopreservation and analysis company, today announced its partnership with Coverdale Clinics Inc., a premium network of specialty care clinics in Canada . Together, Acorn and Coverdale will help make stem cell collection more accessible and affordable in the West Greater Toronto Area .

Through their partnership, Coverdale Clinics' Oakville location be offering Acorn's non-invasive stem cell collection services. The simple process involves plucking a few hair follicles from a client's head, which are then analyzed and cryopreserved for future use.

Acorn's innovative solution for live cell collection enables the collection of stem cells without the need for surgery or other painful and invasive procedures, making stem cell collection for life-long storage significantly more affordable and accessible for everyone.

"Our partnership with Acorn Biolabs opens up a great opportunity for us to expand Coverdale Clinics service offering into the emerging regenerative medicine and geneticsmarket. We're pleased to be able to leverage our specialty clinic in Oakville to offer a service that improves access to exciting and novel health care technologies," said Chris Dalseg , BioScript Solutions' Vice President of Strategic Growth and Marketing. "We have always been at the forefront of providing innovative health care services to Canadians, and adding stem cell collection services from Acorn exemplifies our ongoing commitment."

Once stem cells are collected, Acorn uses its proprietary capabilities to keep cells alive during transportation before going into long term cryogenic storage. The process turns collected hair follicles into a highly valuable and accessible resource for further regenerative medicine and genetics. Not only are these stem cells securely stored for future use, but the company's scientists will also be able to extract critical genetic information through DNA tests, for clients that want it, that will unlock valuable data about a person's health over their lifetime.

"We are excited to bring Acorn's preventative, personalized healthcare services to more people through this partnership with Coverdale Clinics. The cells collected are a life-long resource for these clients, not only in regenerative medicine, but also for advanced analytics, helping to identify diseases even before the first symptom," said Dr. Drew Taylor , Co-founder and CEO at Acorn Biolabs Inc. "The partnership is an important extension for Acorn to serve health-minded individuals in more geographies, freezing the clock on their stem cells so they can use them later in life, when they will need them most."

Clients can book their non-invasive stem cell collection appointment in Oakville, Ontario through Acorn's website today at http://www.acorn.me

About Acorn Biolabs, Inc.

Story continues

Acorn helps you live a longer, healthier tomorrow by freezing the clock on your cells today. Founded in 2017 by Steven ten Holder, Patrick Pumputis and Dr. Drew Taylor and borne out of years of research, Acorn is a healthcare technology company based at Johnson & Johnson INNOVATION JLABS in Toronto . Acorn is focused on giving everyone the best chance to experience more healthy years with its easy, affordable and non-invasive stem cell collection, analysis and cryopreservation service. For more information, visit acorn.me.

About Coverdale Clinics

Coverdale Clinics is a premium network of specialty care clinics, providing patients with a safe, comfortable environment to receive specialty medications by infusion or injection. With more than 100 clinics nationwide, our nurses take a personalized approach to patient care that includes education and counselling to better support medication adherence.

About BioScript Solutions

BioScript Solutions is committed to helping patients with chronic illnesses achieve the best possible health outcomes. With our total care approach, we simplify access to complex, specialty drug therapies and deliver full-service specialty care solutions at every stage of the patient's treatment journey. Through our specialty pharmaceutical distribution, pharmacies, patient support programs and clinical services, BioScript has the capability to manage the needs of manufacturers, payors, prescribers and health care practitioners across Canada today, and tomorrow. To learn more, please visit bioscript.ca.

SOURCE Acorn Biolabs

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Locking in and preserving your healthy stem cells has never been easier and more accessible as Acorn Biolabs partners with Coverdale Clinics. - Yahoo...

Dutch startup Neuroplast raises 4M for its stem cell-based technology to treat patients with Spinal Cord Injury – Silicon Canals

Neuroplast is a company based in Maastricht (the Netherlands) developing autologous stem cell therapies for patients suffering from neurodegenerative diseases such as spinal cord injury (SCI), amyotrophic lateral sclerosis (ALS) and traumatic brain injury.

Recently, the company has raised 4 million from Dutch-based Brightlands Venture Partners and LIOF and from an existing shareholder and informal investor Lumana Invest BV.

CEO Johannes de Munter said:

The financing and support of the investors will enable us to perform multicenter clinical trials in the Netherlands, Denmark, Germany, and Spain and bring the product to market.

This Dutch startup will use the fund to perform a phase II/III clinical trial with the aim of obtaining conditional market approval for the treatment of patients suffering from Spinal Cord Injury.

Founded by physician Hans de Munter and neurologist Erik Wolters in 2014, Neuroplast has expanded with Juliette van den Dolder, who was appointed as COO and management team member.

In the case of SCI, isolating, manufacturing, and reinserting patients own cells, very promising preclinical outcomes have resulted in an Orphan Drug Designation from European regulatory authorities, allowing a fast-track procedure for the clinical trials. These trials are expected to start in March 2020.

Marcel Kloosterman Director at Brightlands Venture Partners:

Neuroplast combines breakthrough science with a solid management team. In a sizable market characterised by major unmet need, successful treatment of (accident caused) paralysed patients would make life so much easier for them and their families while lowering the burden and costs for the society.

Yearly, 24,500 people in Europe and the USA are diagnosed with Spinal Cord Injury, usually caused by accident. Its worth mentioning that for Europe and the US, the medical cost associated with Spinal Cord Injury is over 13 bn per year.

CEO Johannes de Munter adds:

Neuroplast is becoming an ATMP player in the region and wants to contribute to our beautiful eco-system.

Main image credits:Neuroplast

Stay tuned toSilicon Canalsfor more European technology news

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Dutch startup Neuroplast raises 4M for its stem cell-based technology to treat patients with Spinal Cord Injury - Silicon Canals

On the Trail of Cancer Stem Cells – Technology Networks

Two research teams from the Max Delbrck Center for Molecular Medicine and their collaborators have produced a detailed cell atlas of an entire salivary gland tumor in a mouse model, mapping individual cells throughout the tumor and its surrounding tissue. The "single cell" approach, recently described inNature Communications, has provided key insights about cellular composition changes through the earliest stages of cancer development.

A solid tumor is not, as many might assume, a lump of cells that are all the same. Rather it is mix of many different cell types, including a variety of stromal and immune cells besides the actual tumor cells.

"Conventional methods in molecular biology often consider a sample as a whole, which fails to recognize the complexity within it," said Dr. Samantha Praktiknjo, senior scientist and first author from MDC's Systems Biology of Gene Regulatory Elements Lab headed by Professor Nikolaus Rajewsky at the Berlin Institute for Medical Systems Biology (BIMSB). Developing a detailed understanding of the different cells within a tumor and how they interact could help identify more effective treatment strategies.Strength in numbers

The team used single-cell RNA sequencing technologies developed in theRajewsky laband novel epitope profiling to produce the cell atlas, and identified the cells that were specific to the tumor by leveraging the reproducibility and the large sample size of their data.

The latter was possible by using a mouse model, developed in MDC's Signal Transduction in Development and Cancer Lab headed by Professor Walter Birchmeier, which harbors designed mutations that induce a salivary gland squamous cell carcinoma. This system provides a consistent supply of genetically similar tumors to sequence from the earliest stages of development, which is nearly impossible with human patients.

"In a patient, the tumor is already developed and you cannot go back and rewind time and look at how it started," said Dr. Benedikt Obermayer, a co-first author now at the Berlin Institute of Health (BIH). "Here, we have a model that is so controlled, we can watch it happen." And Dr. Qionghua Zhu, the third first author and a former postdoc at theBirchmeier Lab, added: "To fight cancer effectively, we need to find the driver mutations. This method gives us clues about the evolution trajectories of a tumor."

Sequencing technologies have advanced so that it is now possible to quickly and affordably sequence the RNA inside single cells, one at a time, as well as the proteins on the surfaces of cells in the tissues. While other methods grind up the tissue and identify what genes and molecules are present in the mix, the single cell approach precisely identifies how many of each type of cell is present, and which genes and molecules are associated with which cell.

For this study, the researchers sequenced more than 26,000 individual salivary gland cells from mice with tumors and healthy mice. They used computational models to analyze the huge amount of data and identify each individual cell and sort them into groups - such as stromal cells, immune cells, saliva producing cells, cancer cells - based on the hundreds of genes expressed and molecules present.A surprise

The single cell approach revealed something that surprised the researchers: "When I saw the data, I thought, where is the tumor?" Obermayer said. The population of cancer stem cells in the tumor was extremely small - less than one percent of all profiled cells in the tissue. Due to their low abundance, investigation of these cells still heavily depends on assumptions about surface markers and is often performed in cell culture-based systems. Here, the authors were able to identify the cancer stem cells directly from the solid tumor samples with their single cell approach.

Furthermore, the team was able to predict the progression of the different cell types through different stages of tumor development. Their model suggests that the cancer stem cells emerge from cancerous basal cells, then develop into another subtype before ultimately becoming a population of cells similar to luminal cells, a cell type present in normal, healthy salivary glands.

This progression supports the idea that when something goes awry in the basal cells of this solid tumor model, they are triggered to turn into cancer stem cells, which can then become a different type of cell. "What I found fascinating was clearly seeing the order of signals and events, transitioning from the progenitor to the progeny populations of the cancer stem cells," Praktiknjo said.Next steps

Further research is required to verify that individual cells are transforming through these stages, and explore the cellular and molecular interactions driving tumor growth. The team anticipates the approach they've demonstrated here can be applied to other cancer types as well.

"To me the main conceptual insight is that we can apply ideas from single-cell based developmental biology to reconstruct molecular progression of tumorigenesis ," said Professor Nikolaus Rajewsky, who heads MDC's Systems Biology of Gene Regulatory Elements Lab and is the scientific director of the BIMSB.

Reference:Praktiknjo, et al. (2020) Tracing tumorigenesis in a solid tumor model at single-cell resolution, Nature Communications, DOI: 10.1038/s41467-020-14777-0.

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

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On the Trail of Cancer Stem Cells - Technology Networks

UCLA researchers identify compound that could improve lung disease treatment – Daily Bruin

A UCLA study identified a chemical compound that may improve lung health, potentially suggesting new approaches to preventing and treating lung diseases.

According to the study published Tuesday in Cell Reports, the UCLA team discovered a compound now named Wnt Inhibitor Compound 1, or WIC1, that successfully improved the health of isolated cancerous human and mouse airway cells.

The compound targets a group of molecules, called the Wnt/-catenin signaling pathway, that is more activated in the lungs of people with precancerous lesions or lung cancer than in the lungs of healthy people. Elevated activity in this pathway has also been linked to lung cancer in other studies.

The researchers tested around 20,000 compounds on their abilities to block this pathway in the process of identifying WIC1.

The researchers also found that the compound WIC1 was far less toxic than other known inhibitors of the Wnt/-catenin signaling pathway. The compound could therefore be used to develop safer drugs to prevent and treat lung diseases linked to the pathway.

Led by Brigitte Gomperts, a UCLA professor of pediatrics and of pulmonary medicine, and Cody Aros, a molecular biology graduate student, the team is planning to further investigate the safety of WIC1 and the mechanism by which it blocks the pathway.

The study was supported in part by the National Institutes of Health, the National Cancer Institute and the Broad Stem Cell Research Center Training Program.

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UCLA researchers identify compound that could improve lung disease treatment - Daily Bruin

New informative research on Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market 2020 | Major Players: Orange County Hair Restoration…

This industry research presents the Global Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market size, historical breakdown data (2014 2019) and forecast (2020 2025). This report provides the estimation of market size and volume. Both top-down and bottom-up approaches have been used to estimate and validate the market size of Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies market. For the data information by region, company, type and application, 2019 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.

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On the basis of products, the report split into: Platelet Rich Plasma Injections, Stem Cell Therapy

On the basis of the end users/applications:Dermatology Clinics, Hospitals

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New informative research on Stem Cell and Platelet Rich Plasma (PRP) Alopecia Therapies Market 2020 | Major Players: Orange County Hair Restoration...

BEGEV Salvage Regimen Linked to High Complete Remission Rates – Cancer Therapy Advisor

Previous research has suggested that patients with classical Hodgkin lymphoma who are refractory to or relapse after first-line therapy may be more likely to be cured after receiving second-line salvage chemotherapy followed by autologous stem cell transplantation (ASCT) than after receiving standard-dose chemotherapy.1,2 High complete remission rates prior to ASCT have been shown to predict better long-term outcomes for patients with the condition.3 Researchers have investigated a number of combination therapy regimens as induction regimens prior to ASCT for refractory to or relapsed lymphoma, yielding pre-ASCT CR rates ranging from 20% to 54% and overall response rates (ORRs) of 60% to 80%.4

A prospective multicenter single-arm phase 2 study also indicated that the combination of bendamustine, gemcitabine, and vinorelbine (BEGEV) as second-line chemotherapy before ASCT, in 59 patients with relapsed/refractory (R/R) classical Hodgkin lymphoma, resulted in a CR of 73% and ORR of 83%.5

Now, updated 5-year results from that same study have confirmed the benefits, showing a CR rate of 75% and ORR of 83%.6 But experts cautioned that a randomized trial would be needed to determine whether the regimen is superior to other treatments.

The update[d] 5-year results ofBEGEV (bendamustine, gemcitabine, vinorelbine) followed by autologous stem celltransplantation in patients with Hodgkin disease refractory or relapsing tofirst-line therapy confirm the significant data in terms of CR rate (75%) aswell as PFS (59%) and overall survival (78%), lead study author ArmandoSantoro, MD, director of the Cancer Center at Humanitas Research Hospital,Milan, said in an email.

The trial involved 27 patientswith classical Hodgkin lymphoma who were refractory to and 32 patients whorelapsed after receiving 1 line of chemotherapy. The patients received 800 mg/mgemcitabine on days 1 and 4, 20 mg/ m vinorelbine on day 1, and 90 mg/mbendamustine on days 2 and 3. The patients received 100 mg prednisolone on days1 to 4. They were given 4 cycles of BEGEV every 21 days.

Those patients who experiencedcomplete response or partial response after completing the 4 cycles receivedmyeloablative therapy with carmustine, etoposide, cytarabine and melphalan orfotemustine, etoposide, cytarabine and melphalan, which preceded the reinfusionof CD341 cells.

The researchers evaluated diseaseresponses before and after the fourth BEGEV cycle using computed tomography and18F-fluorodeoxyglucosepositron emission tomography scans accordingto the International Working Group response criteria.

The treatment prompted CR in 44patients (75%) and partial response (PR) in 5 (8%), yielding an OR of 83%. Theauthors noted that the CR rate was higher than the 54% CR rate previouslyreported for the ifosfamide, gemcitabine, vinorelbine, and prednisolone (IGEV)regimen as well as other second-line chemotherapy-based salvage regimens.

Of 49 patients who responded toBEGEV and were eligible for ASCT, 43 ended up receiving transplants. After 5years following BEGEV treatment, the PFS for all series was 59% and OS was 78%.More than 90% of patients were at high risk for relapse post-ASCT. At 5 years,33 patients who received transplants experienced continuous CR, 7 relapsed, and3 died due to unrelated factors that included pneumonia, infection, andmultiorgan failure.

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BEGEV Salvage Regimen Linked to High Complete Remission Rates - Cancer Therapy Advisor

From Germany with love: Alfie, four, meets his stem cell saviour – Express

Alfie Commons and mum Lorna, 40, met Christin Bouvier, 34, for the first time on Wednesday after spending more than two years communicating via anonymous letters due to donation laws.

Alfie, from Toton, Notts, was diagnosed with acute lymphoblastic leukaemia (ALL) at seven months after he had a cold for six weeks.

After chemotherapy failed, Alfie was put on a trial immunotherapy drug which helped him to recover to be eligible for a stem cell transplant.

Unable to find a family match, his family found Christin on a worldwide register operated by blood cancer charity DKMS. She donated her cells in a one-hour op and they were flown to the UK and slowly passed into Alfies body in August 2016.

When the teacher, from Schwerin, Germany, was finally allowed to meet the family at Chiswick Town Hall in west London, the little boy gave a gift of Lacoste Pink perfume.

Mum-of-two Lorna, who works in HR, said: The meet-up was just amazing, it was everything we could have possibly dreamed of there were lots of hugs and tears.

It didnt feel like I was meeting her for the first time because wed been chatting for so long before.

As a family, we owe so much to Christin, words of thanks will never feel enough.

Christin just cried when she heard the recipient was a baby. She said: After I donated my bone marrow and the anaesthetic wore off, I called DKMS.

They told me that Alfie was a small baby and living in the UK but couldnt tell me any more due to the laws. When I found out Alfie was responding to treatment, so many tears of joy ran down my face. I still cant describe that moment.

Its a moment that is always with me. Whenever I feel a bit down, I think back to it as it always brings me so much happiness! She added that the meeting was so amazing. I was very nervous and shaking at first and when we finally met we cried a lot and hugged.

Alfie was shy at first but after a bit of time he became more comfortable and we played with some balloons and had a slice of cake.

After the transplant, Alfie developed a deadly immune condition, but this was controlled by medication. He was given the cancer all-clear in 2017 and has started school.

Lorna added: I just want more people to sign up to become donors theres a match for everyone.

Originally posted here:

From Germany with love: Alfie, four, meets his stem cell saviour - Express

Stream It Or Skip It: Utopia Falls On Hulu, Where Teens From A New Earth Colony Who Discover The Power Of Hip-Hop – Checkersaga

Hulu is billing Utopia Falls as the primary ever sci-fi hip-hop tv collection, and its simple to see why such a factor hasnt been created earlier than. Sci-fi has been a typically white style, and one whichs extra involved with drama than dancing, singing and rapping. That will sound like were being wiseasses, however nothing might be farther from the reality; the concept a sci-fi present might be made out of a youthful, extra various perspective is a welcome change. However is Utopia Falls that present?

Opening Shot: As we see an aerial shot of the clouds over Earth, then we begin panning into Earths barren panorama, we hear a voice over go, They are saying, time is the best thief there may be.

The Gist: As we pan over, we see that a lot of the land is uninhabitable. However then we see, below an environmental bubble, the colony generally known as New Babyl. Its the final working colony on Earth, established lots of of years after the ancestors of apocalyptic survivors went underground to dwell. Its the day when the 25 teenagers from the colonys numerous sectors are chosen to coach for a musical-dance competitors referred to as The Exemplar.

Aliya (Robyn Alomar) is a information within the Progress Sector and is the daughter of Gerald (Jeff Teravainen), a member of the Tribunal, who advise the Chancellor Diara (Alexandra Castillo), the chief of the colony. Her boyfriend Tempo (Robbie Graham-Kuntz) has additionally been chosen. Over in Reform Sector, primarily a nicer model of a jail colony, finest buddies Mags (Robbie Graham-Kuntz) and Bohdi (Akiel Julien) are picked; the primary time two from that sector are going. Sage (Devyn Nekoda), from the Nature sector, is so certain she receivedt go she doesnt even watch the announcement.

After the announcement, Diara and the Tribunal discover out that there was a breach within the colonys protecting bubble, that means that both somebody got here in or somebody left.

Once they college students get to the power the place they practice for The Exemplar, theyre greeted by Mentor Watts (Huse Madhavji), who tells them that their first efficiency is in ten minutes. Throughout that point, Bohdi and Aliya get in a tiff over what Bohdi thinks are her apparent benefits. After the efficiency, Watts takes down the mostly-confident college students by saying the performances have been common, and instantly kicks out the three worst performers to indicate the scholars how severe that is.

A lot of the new college students are invited to a mysterious celebration proper exterior the borders of the colony, which is taken into account to be off-limits; the invite says anybody who attends will get a leg up on the competitors. When Bohdi and Aliya separate from the remainder, they discover a door within the woods. Once they go in, they discover one thing referred to as The Archive (voice of Snoop Dogg) that introduces them to an historic type of music: hip-hop.

Our Take: Theres a number of good issues about Utopia Falls, created by R.T. Thorne, recognized for guiding collection like Discover Me In Paris and Blindspot. Each Alomar and Julien are interesting leads (its fairly obvious that theyre the leads of whats going to be an ensemble), they usually each do good work in a primary episode that roughly appears like Glee set lots of of years sooner or later. The complete ensemble must be multi-talented, both as dancers, singers, musicians, in addition to actors, and it appears like Thorne has discovered actors that may create plausible characters with some depth.

However the story, as with most Sci-fi thats attempting to construct a brand new world out of nothing, can get complicated. As a lot as Thorne tried to present some exposition to start with of the episode, it felt like we dont know practically sufficient about New Babyls numerous sectors, what The Exemplar truly is, how some persons are associated to one another (Sage, as an example, has a Gran Chyra (Diane Johnstone) and Gran Reale, however were undecided in the event that they raised her or are simply two of her grandparents). Additionally, stilted language abounds, like when persons are mentioned to be of their 17th 12 months as a substitute of simply saying theyre 16. The temptation to jargonize on a regular basis speech to make it sound futuristic has at all times been a pitfall of sci-fi, however the very best of the style has its characters talking in up to date talking patterns; when Thorne strays from that, it instantly loses us.

We get that this present is probably going geared in direction of a youthful viewers, however we hope that the concept the colony might seem to be a collective however in actuality comes off as a North Korea-esque totalitarian state will likely be addressed. Everybody vows loyalty to the leaders, and when these leaders name to their costs on large screens, the present feels much less like a teen dancing and singing present and extra like 1984. Maybe because the affect of hip-hop, and far of the styles message to problem authority, permeates with the scholars, that subject will come to the foreground.

Intercourse and Pores and skin: Nothing.

Parting Shot: Surrounded by holographic photos of album covers, music movies and breakdancing, Aliya and Bodhi sit and soak up the historical past of hip-hop.

Sleeper Star: Wed watch each episode solely to listen to Snoop Dogg because the voice of The Archive. If we didnt see his identify within the opening credit, listening to his voice would have been one of the out-of-left area issues weve encountered on TV thus far in 2020.

Most Pilot-y Line: Moore Instances (Dwain Murphy), an influential buddy from the Reform Sector, tries to get Bodhi and Mags to present out black market footwear to the scholars. Bodhi refuses. Hes been like a father to us! Mags says to Bodhi. To start with, you may hold that father speak, Bodhi replies. Whoo boy, plenty of historical past in that sentence.

Our Name: STREAM IT. Were undecided if Utopia Falls goes to get higher than the primary episode, which we discovered hokey at instances. However well hold watching simply to listen to extra Snoop Dogg, and if the present improves, all the higher.

Joel Keller (@joelkeller) writes about meals, leisure, parenting and tech, however he doesnt child himself: hes a TV junkie. His writing has appeared within the New York Instances, Slate, Salon, VanityFair.com, Playboy.com, Quick Firm.com, RollingStone.com, Billboard and elsewhere.

StreamUtopia Falls On Hulu

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Stream It Or Skip It: Utopia Falls On Hulu, Where Teens From A New Earth Colony Who Discover The Power Of Hip-Hop - Checkersaga

Grinning werewolf: Thoughts on the massacre in Germany – Arutz Sheva

Alexander Maistrovoy The writer is a graduate of Moscow Univ. in Journalism, worked there in his field and made aliyah in 1988. He works at the Russian language newspaper Novosty Nedely, has had articles posted on many internet sites and authored Ways of God about different religious and ethnic groups in the Holy Land, and with Mark Kotliarsky the Russian book Jewish Atlntida.

A century ago, in 1918-20, Europe sunk into the red terror. Inspired by the Russian revolution, people with red armbands, red flags and red stars were determined to celebrate the new bright future. At factories, the power was transferred to factory committees, banks were nationalized, churches were turned into food and military warehouses, monuments were demolished, people were forcibly mobilized into the Red Army.

Extraordinary commissions murdered the enemies of the people and their families and deprived them of land and property. The Bavarian Soviet Republic, Hungarian Soviet Republic, Slovak Soviet Republic, Alsace-Lorraine Soviet Republic, Bremen Soviet Republic, Red Finland - the creators of the great Utopia destroyed everything that was associated with traditional values, ideals and virtues.

Nowadays no one seems to remember it. The Left will not benefit from those memories; the Right dreads accusations of whitewashing Nazism.

The outcome was dramatic. The consequences of the attempted social experiment on a living body of society were brutal - at first spontaneous, then organized: Furious nationalism, revived racial phobias and unrestrained thirst for revenge. Even enlightened intellectuals such as Thomas Mann were caught up in the wave of hatred. Utopia choked on blood in Russia.

In Europe, the nationalists won: Moderate and prudent, like Mannerheim; cruel but predictable, like Admiral Horthy; and monstrous like Hitler.

A lot has changed in the last hundred years. The Soviet empire collapsed, Eastern Europe resurrected and gained solid immunity from universalistic theories; the World Revolution of the Third World failed, a good manyJews directed their unrestrained temperament to create their own state.

Only one thing has remained unchanged: the passionate faith of the Western elite inperverted Utopian In the 21st century, once again the world has entered a vicious cycle of revolution and reaction. The reaction has already begun. Terror of loners, attacks on mosques and synagogues, atrocities in Utya, Christchurch, Galle and now Hanau are its first signs.theories of all sorts and kinds. As result, in the 21st century, once again the world has entered a vicious cycle of revolution and reaction.

The reaction has already begun. Terror of loners, attacks on mosques and synagogues, atrocities in Utya, Christchurch, Galle and now Hanau are its first signs.

It was predictable, explainable and logical. The globalist quasi-Marxist ideology has turned the inhabitants of the Third World and, especially, Muslims into people of the highest sort. They became the 'proletariat' of modern times and in sharp contrast,'white straight males' became the symbol of repression, racism and violence, 'the new world enemy'.

But the people refuse to agree with the destruction of the thousand-year-old foundations, family, faith and traditions. They refuse to be marginal in their own countries. Forcefully implanted alien culture is rejected by the society and in such an atmosphere psychopaths take up arms and kill those they think are the operatives of a new pseudo-religious sect and their allies.

You can turn a blind eye to it, ignore the causal relationships, yell about the racism of the white society, but it does not change the essence.

This is a reaction to violent fanatical implantation of Utopia, regardless of how its labeled: Marxism, Globalism, Progressivism, Multiculturalism, Political Correctness, Intersectionality, Political Identity, Cultural Diversity or Tikkun Olam. They are all the same. It is reaction to Antifa, BLM, Islamic terror, Muslim culture of raping and bullying.

Loner psychosis is a precursor of mass psychosis. Red Plague generates a Brown Plague.

In Germany, a country so prone, alas, to outbursts of psychopathy, the number of neo-Nazis is growing. These are not the moderate nationalists from AfD or Pegida. They are the real Nazis, the direct followers of the Fuhrer. According to BfV, their number over the past two years (i.e., after a wave of refugees) increased by 50%. They are engaged in martial arts. They draw the Werewolf, a symbol of the SS, they wear Adolgf was the best and I [heart] HTLR T-shirts, arrange Kampf der Nibelungen (Battle of Nibelung) and prepare for D-Day.

We see how the ideas of the Third Reich gain power in Western culture again from the USA and Canada to France. They no longer try to conceal it. Their time is approaching, because the soil has already been fertilized for them by the progressives.

Because of the globalists and progressives the Western world is plunging into chaos and hatred. Only a small groupof lucky people will get the next Mannerheim. However, and almost certainly, most of them will get new Fuhrers.

The carriers of New Utopias are by far more guilty for wronging their people and history than their predecessors with red flags in Bavaria and Hungary.

First, Russia with its despotism of Tsars, the Pale of Settlement and the Okhrana (secret police) as well militaristic Prussian Germany were seriously ill. The horrors of the Great War and the cloaca of the Industrial Revolution devastated the soul of the West. But the current progressives have inherited healthy, stable, and prosperous communities. Essentially all the flaws and shortcomings of the past were eliminated or nearly eliminated: discrimination of national and sexual minorities and women, social ulcers, industrial lumpen and mass poverty.

By carrying out the program of ethnic substitution by mass migration from Third (especially, Muslim) world and by destroying cultural and religious values of their people, the globalists dont demolish dying, rotten regimes, instead they bulldoze successful democratic states.So by carrying out the program of ethnic substitution by mass migration from Third (especially, Muslim) world and by destroying cultural and religious values of their people, the globalists dont demolish dying, rotten regimes, instead they bulldoze successful democratic states.

Secondly, Lenin, Trotsky, Bela Kun, Dzerzhinsky were sincere idealists, they had not yet had the sinister experience of the 20th century. They could still indulge themselves in the probable success of their social experiment. But Corbyn, Sanders, Obama, Trudeau, Elizabeth Warren, Mlenchon, Kamala Harris, Juncker or Macron are not idealists. These are hypocritical plutocrats and manipulators of consciousness, craving for power and glory. Thus, by this becoming more ignominious.

And finally, third and most important. Marxism grew out of Utopian communism, rooted in the Judeo-Christian tradition: from Jewish prophets, Essenes and early Christians to Thomas Mntzer and the Anabaptists, the Illuminati of Adam Weishaupt, Thomas More and Tommaso Campanella, Saint-Simon, Charles Fourier and Robert Owen.

Their views (no matter how weevaluate them) were based solely on Western culture itself. They had nothing to do with the archaic, primitive and cruel cults of backward peoples and surely had nothing in common with gloomy dogmatic and aggressive Islam with female circumcision for girls, intimidated women, rituals of stoning unfaithful wives and homosexuals, bloody vendetta, the slave trade and the division of humanity into faithful and infidel. Islam was a symbol of anti-utopia for them. They would have turned in their graves, had they learned that their heirs represented by new Western elite open their gates for crowds of primitive savages.

Man is a part of nature and obeys its laws. According to Newton's Third Law of Motion, For every action, there is an equal and opposite reaction. Transgression of human nature yields violence and monsters - three monsters in our case: Red, Brown and Green ones. Prosperous, stable and tolerant communities have been replaced by Red-Green Hydra, on the one hand, and a Werewolf, on the other.

However, who is Newton to dictate the laws to a progressive-minded person? No more than a Dead White European Male...

Author of Agony of Hercules or a Farewell to Democracy (Notes of a Stranger), Available at Amazon and Barnes & Noble.

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Grinning werewolf: Thoughts on the massacre in Germany - Arutz Sheva

6 of the Best Places to Drink in New Orleans – Big Easy Magazine

There are a lot of bars and restaurants in New Orleans that serve delicious cocktails. Because of the vast number, it can be hard to find the right one youre looking for. To help you with your search for the best spot to sip at, weve come up with a list of the best places to drink in New Orleans. From easy day drinking spots for your brunches with the girls that turn into all-day affairs, to the late-night bars for your friends bachelor party, we want to make sure you know all the best spots. Take a look!

Even if youre not a tourist, this bar is still an enjoyable place to visit and sip at. The bar was built into a moving carousel. If youre worried about getting motion sick, dont worrythe bar spins slowly enough that youll barely notice. You have to try out the bars most famous cocktail, the Vieux Carre.

If you and your friends are beer lovers, then youll definitely want to head to the Bulldog. Its got a great patio and some of the best bar food in the area. Its an awesome spot if you want to get away from the tourists of the French Quarterfor a chill night, this patio is the place to visit. They have around 50 beers on tap, so dont miss out!

On the other hand, if youre more of a wine lover, then Bacchanal is the place to be. Previously a quirky little wine shop, its now evolved into this wine garden utopia where people can spend a night sipping on crisp wine, order wine and cheese, and enjoy live music. The backyard is massive, but if thats not what youre feeling, they also have a cocktail and wine bar upstairs.

Just finished up your walk or bike ride? Make a pit stop at the Wrong Iron to slake your thirst with their wide selection of beers, cocktails, and frozen cocktailsall on tap! They have racks for your bikes, a beer garden if you havent gotten your fill of sunshine, and an atmosphere that youll have a hard time leaving.

The dive bar to end all dive bars, Lafittes Blacksmith Shop is the late-night place to be. Sure, everyone has their own opinion on which is the best dive out of the 582 bars on Bourbon Street, but this one is one of the oldest bars in America. Theyve been serving beer and frozen drinks since the 1700sits a must-visit.

Live music describes New Orleans in a nutshellTipitinas is its institution. Though you could close your eyes and point to find a live music join on Frenchmen Street, this is one of the best places to go for music and drinks in the whole city. Plan to come when a local brass band is playingits an experience youll never forget.

As fun as it is to explore New Orleans and find your favorite new drinking spot, make sure youre doing so responsibly. Never drink and drive, and always understand how alcohol affects your body. Even if youre walking, alcohol affects your mood, so play it safe and know your limits. Happyand safesipping!

Hey guys!

Were so grateful to our friends, our families, our neighbors, and especially our readers for chipping in, sharing, and donating to the cause of local progressive media. Your support has lifted us up so much and will most assuredly not be lost or forgotten.

If you care about local independent progressive media in an era where multi-millionaires such as John Georges are monopolizing our local press, then please donate any amount you can to make our operation a success. We can do this! Do not give up.

What else can you do if youve already donated and cant donate anymore? Share our content on Facebook and tell people about our fundraising operation. Call and email others who may be able to give. We believe in you because you believe in us and together we can ensure Big Easy Magazine becomes a progressive icon for New Orleans and an inspiration for the expansion of progressive media around the world.

Thank you,Scott PloofPublisherBig Easy Magazine

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6 of the Best Places to Drink in New Orleans - Big Easy Magazine

Why The Inheritance Imploded On Broadway – Forbes

Atmosphere outside the Ethel Barrymore Theatre on November 17, 2019 (Photo by Bruce ... [+] Glikas/FilmMagic)

The British import that was once touted as the greatest thing since sliced bread quickly turned out to be toast.

After struggling to find an audience on Broadway, The Inheritance will close next month after 138 performances. We are all extremely proud of this production and the 32 actors who bring this ambitious story to life eight times a week and honor the legacy of those weve lost to the AIDS epidemic, stated the lead producers of the play.

Yet, the implosion of The Inheritance on Broadway might seem a little surprising after its significant success overseas.

The $9.1 million play arrived in New York last September as what several publications described as one of the most buzzed-about shows of Broadways fall season. It had received more awards than any other new play opening on the Great White Way, and defeated The Lehman Trilogy to win the Olivier Award for Best New Play in Londons West End.

Here is the play of the year, and last year, and quite possibly next year as well, praised one British critic. It instantly looks like a modern classic, perhaps the most important American play of the century so far, echoed another reviewer, giving it five stars.

Yet, despite the great fanfare in the West End, The Inheritance often earned less than half of its potential revenue each week on Broadway, and sometimes made even less than its $460,000 weekly operating costs. The two-part play, which had sold every single seat during its premiere at Londons Young Vic Theatre, also failed to fill up more than two-thirds of the seats at the Ethel Barrymore Theatre during most weeks.

Its reviews on Broadway did not help.

In contrast to the rave reviews that the show received overseas, one critic on Broadway wrote that The Inheritance isnt a great play or even a very good play, but [playwright Matthew] Lopezs opus is compelling watchable in the way that old so-bad-theyre-good movies are: finger-snapping one-liners and dramatic fireworks explode throughout as logic and character development are abandoned. You will be riveted watching this lurid, weepy, pandering, derivative, and very grand soap opera, the reviewer continued.

Hoping to hit the jackpot on Broadway, the producers had counted too much on it being so well received in London, commented drama critic Michael Portantiere. Because The Inheritance had been showered with awards left and right overseas, many individuals expected that it would continue to receive praise in New York.

But, a smash hit in the West End doesn't necessarily guarantee the same success on Broadway, said marketing executive Maris Smith, who previously helped develop marketing strategies for Broadway shows like Mamma Mia! and Annie.

While receiving rave reviews in New York might have helped the show become a must-see event like Hamilton, Springsteen on Broadway, and American Utopia, Broadway theatergoers have different tastes than British theatergoers, and the divergence appears to be significant for shows set in the United States that are presented in London.

When The Inheritance was performed in the West End, it must have a little bit romantic for London audiences to see New York gays, explained Sam Maher, a Broadway producer and influencer marketing consultant. It was probably so cool for British audiences to see what life is like for homosexual men across the pond, he said, and, for the most part, they are not as critical, because it is not their everyday lives, and they dont have ownership over it, echoed Portantiere.

But, when The Inheritance was performed in front of New York audiences, the characters and their lives seemed a little less enchanting. These are gays who we know, Maher said. Gay men we know are going to Fire Island, and there are older gay men we know who have houses upstate, he said. We know this story, Maher stated.

Its story of love and loss in the aftermath of the AIDS epidemic might have been too familiar and too close to home for some Broadway theatergoers, much like the British play Enron, which received rave reviews in London and then closed after only 16 performances on Broadway in 2010. While British audiences found the story of a financial fraud at a large American corporation to be fascinating, [o]n Broadway, maybe because the Goldman Sachs story was unraveling nightly on television, or maybe because the Enron collapse was a terrible episode best forgotten, whatever it was, the Wall Street crowd didnt come, recalled Matthew Byam Shaw, one of its producers. Many New York theatergoers did not want to spend their free time watching a show about financial misconduct after losing money in the recession, and, likewise, many New York theatergoers might not have wanted to spend their free time watching a show about life as a homosexual man in Manhattan after losing loved ones in the AIDS epidemic.

Also, the fact that a major character is a Trump voter ... might be a little too raw for New Yorkers, surmised Maher. British people can say, it [stinks] for you guys over there with Trump, he said. But, for Americans, this is a reality that we are living with everyday, and this is too raw to make jokes about or to try to analyze on stage, Maher commented.

In addition, the play might have been too long to attract most Broadway theatergoers.

With two parts spanning over six hours like Harry Potter and the Cursed Child, The Inheritance was not a casual walk to the TKTS Booth, and choose your show for the night type of deal, said Smith. It required setting aside either one full day or two blocks of time during the week to watch the full show, as well as purchasing two separate tickets. It is a tough ask monetarily and time-wise, explained Maher, and the schedule of the play might have been inconvenient for tourists with a limited amount of time to see shows in New York.

In addition, once the play opened on Broadway, and the marketing team replaced the flattering remarks from the British press with vague excerpts from the Broadway reviews, some individuals felt that their efforts to attract local theatergoers were misguided. Some of the decisions they made seem so wrong-headed, especially the ridiculous attempt to make the show as a love letter to New York City, Portantiere stated. It doesnt have anything to do with that, he said, highlighting that a lot of the action doesnt even take place in New York City.

It was tremendously misleading, Portantiere complained.

Also, Maher believes that, while The Inheritance was not marketed much, the show relied too much on traditional advertising techniques, such as creating posters with the shows logo and some review excerpts. Key art and pull quotes kind of do nothing these days, he said, arguing that influencer content is much more compelling and engaging, and can convert ticket sales a lot better than bus stop ads with pull quotes.

With limited marketing and no Hollywood actors like Tom Hanks, I have not heard The Inheritance mentioned in the cultural zeitgeist since it opened, Maher realized. In fact, the only time that I am reminded that it is still there is when I sort the [Broadway weekly box office] grosses each week from lowest to highest to see which shows are really struggling, and I see that it has been among the lowest for the past two months, he admitted.

But, even when Broadway theatergoers did learn about the show, and chose to watch it, some individuals in its target audience might have been disappointed.

The gay community in New York has kind of rebelled against the show, Maher observed, adding that so many gay men of color were against it. He noticed that a lot of people of color were asking, where are the people of color in the story? Whereas the Caucasian character supporting President Trump received a lot of time on stage, people of color were very minor characters, and they were not front and center, he said.

The story was about older generations versus newer generations, and not about race, Maher recognized. But, in 2020, it is really hard for a culture of metropolitan queer men to champion something that is so white-centric, he said.

Also, Maher thought that the decision to cast straight actors as the leading homosexual roles in the show might have upset some theatergoers. It made Maher, a homosexual male, not feel represented, he said, and the whole show felt like a rehearsed representation of gay men instead of actually involving those people.

All those things conspired to make someone who is very woke think that this show is not very woke, Maher stated.

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Why The Inheritance Imploded On Broadway - Forbes

Hulu’s ‘Utopia Falls’ Shows That Big Government Isn’t Your Friend, It’s Your Captor – NewsBusters

I love that dystopian stories are in for young adults right now because, hopefully, theyre taking some of these messages to heart. In Hulus new offering Utopia Falls, the message is clear: the big government that says theyre keeping you safe is actually keeping you in prison or enslaved - you just havent figured it out yet.

The plot of Utopia Falls, which debuted on February 14, centers around a group of 16-year-olds in the city of New Babyl who are competing in a performing arts event known as The Exemplar. It is an honor to compete in this event which honors the city and its founder, Gaia, and the winner will be considered an example for other young people. The beginning of the first episode The World is Yours gives us a glimpse of the propaganda under which citizens live.

Aliyah: Here, in New Babyl, where we all work in harmony. No one wants for food or work or sense of community. Regardless of your ancestry, age, or gender, everyone has a purpose.PA Announcement: For state, for community, for all.Crowd: For state, for community, for all.Aliyah: Some citizens work the land, cultivating and harvesting plant and insect life for medicinal purposesas well as providing nourishment for the entire colony, while others work with those who transgress against the state to help rehabilitate them back into society. But the youth of New Babyl have the most important duty of all. We train our whole lives so we can honor our founders through performance in the citys most prestigious competition: The Exemplar. Our society strives to create a better future while being ever-mindful of the mistakes of the past. We may not remember, but we are all aware of the dangers of technology when used for personal benefit instead of the common good. This was the legacy of our founder, Gaia, who led the last of humanity out of the darkness and into the light. And we all take comfort knowing our leaders, The Tribunal, watch over us while our protectors, The Authority, keep us safe and secure.

When Aliyah (Robyn Alomar) enters the competition, she and select exemplars are invited to attend a party in the forest, beyond where citizens are allowed. There, they discover a secret door with an archive (voiced by Snoop Dogg) that holds relics of the old world. Using this forbidden technology, they have access to something even more forbidden - information. They learn about music, dance, and how people of the past used the arts to change the world. They incorporate some of these moves into their dancing and get increasingly in trouble. The Authority cracks down on any changes to their dress (they like diversity, but not personal expression, the kids are told), people are ghosted by the government (they are taken away and never return), and the exemplars start to realize that New Babyl isnt actually protecting them.

They have always been told they live within a forcefield to keep them safe from environmental harm. In truth, it is to keep them imprisoned. They find out there are actually three cities in this new world, they are not alone as they thought. They are actually something of a prison colony, somewhere undesirables are sent. People are told whether or not they can have children, because some genes are not good for society. No warrants are necessary and anyone deemed suspicious can be detained. Gatherings have to be sanctioned. In fact, a lot of the rules they break are things many take for granted as protected rights under our Constitution.

The end of the show sees some exemplars in prison and others having escaped, trying to get through the forcefield and into freedom in another city. We will have to wait for season two to see how they fare. Then again, maybe it wont get a season two to resolve everything, making it more realistic for the people stuck in oppressive regimes. Lets hope that it gives people pause when thinking about what they value in America. I dont think its a coincidence the show came out in an election year, but I think its entirely possible that the creators didnt understand the message of their own show.

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Hulu's 'Utopia Falls' Shows That Big Government Isn't Your Friend, It's Your Captor - NewsBusters

Presidential Politics in the US is a Bonfire of Borough Billionaires Now – Qrius

In the most recent Democratic presidential primary debate in Nevada, MSNBC journalist Chuck Todd asked candidate Bernie Sanders aprobing question, What did you mean that you dont think they [billionaires] should exist?

Sanders described the effects of an economic system that allows for a grotesque and immoral distribution of wealth and income. Todd then turned to candidate Mike Bloomberg to ask the provocative question: Mayor Bloomberg, should you exist?

Here is todays 3D definition:

Exist:

For any concrete thing, to have the state of being that implies a presence in the world. For everything else, to be present in thought alone in some peoples minds, which implies that such things can as easily not exist as exist.

People exist in the real world. The idea represented by the word billionaire is a description not of an individual person but of a relationship between a being and an idea of worth translated into the terms of monetary value.

Sanders answered Todds question by explaining the meaning of his remark in moral terms. He gave an example, complaining that when one persons wealth is more than that of the bottom 125 million living in the same society, it should be deemed wrong and immoral.

Morality is of course an abstract, culturally-determined concept. The principles that define it for any group of people are variable. Nevertheless, every human society proposes and finds multiple ways of enforcing a widely shared sense of morality. This sense of morality provides guidelines for both spontaneous human interaction and the drafting of laws.

Sanders appeals to this general sense of morality that some people call decency. He pertinently answers Todds question, making it clear that the meaning of billionaires shouldnt exist is very simply that society would function better if it could find ways of limiting excessive wealth. In no way does it suggest that billionaires should be removed from society. But Chuck Todds second question, addressed to Mike Bloomberg, shows that he has no patience with subtle or even obvious distinctions. He asks Bloomberg whether he himself, as a person (and not as a billionaire) should exist. Its as if Todd hasnt been listening to Sanders response but is simply reading his next prepared question.

Bloomberg shows a deeper understanding of Sanders meaning when he answers Todds question with these words: I cant speak for all billionaires. Unlike Todd, he acknowledges that the question is about the morality of being a billionaire rather than about any given billionaires right to exist. He then defends himself by affirming that hes giving it all away to make this country better, which sounds very moral indeed, if slightly hypocritical, because in reality he has been usingmountains of his moneyto buy advertising and the loyalty of local politicians across the nation.

Todd adds to his own confusion when he frames a new question to Bloomberg: Have you earned too much should you have earned that much money? Now he has moved to the moral plane in contrast to his earlier existential questions. Should signifies something that is morally permissible. The appropriate answer to that would involve defining the limits of permissible behavior. But Todd is a journalist, not a philosopher. He asks the question not to explore the moral issue, but to provoke a defensive answer from Bloomberg, perhaps even hoping to goad the billionaire to attack Sanders for presuming to define how much money is permissible.

As is often the case with TV journalists like Chuck Todd, the meaning of the question is skewed by both the verb he chooses, to earn, and the noun, money. He assumes that Bloombergs wealth was earned, whereas all everyone knows is that Bloomberg has accumulated what financial analysts refer to as a massive net worth. There is no reason to assume Bloomberg earned it. In practical terms, its impossible to imagine anyone earning that amount of money, which is precisely what Sanders suggested by calling it grotesque. Thebasic meaningof the verbto earn is to receive money for work that you do. Can anyone do $60 billion worth of work, even over an entire lifetime?

By calling Bloombergs fortune money, Todd takes another liberty with the language and an even greater liberty with the logic of the debate. The net worth of a capitalist is the result of two operating principles. The first is that its the billionaires investments that are doing the work, not the billionaire. And, as Sanders aptly points out, other people had a hand in the process: Mr. Bloomberg, it wasnt you who made all that money. Maybe your workers played some role in that, as well.

Even Bloomberg was careful to avoid claiming he earned hisbillions. He boasted: Im a philanthropist who didnt inherit his money but made his money. Making is not the same thing as earning. The distinction is important, but Chuck Todd again shows little interest in linguistic distinctions.

The concern with concentrated wealth is nothing new in history, even if the media treat it as if it was a problem that has only arisen in the last 10 years. In his famous book, Utopia, 16th-century English humanist Thomas More expressed his astonishment at the spontaneous admiration people could have for the wealthy, not because of their moral qualities, but exclusively because of their wealth. He mentioned the folly of those, who, when they see a rich man, though they owe him nothing, and are not in the least dependent on his bounty, are ready to pay him divine honours because he is rich.

This could be taken for a description of some of todays establishment Democrats, who to a large extent do in fact depend on billionaires bounty. Then there is the case of The New York Times columnist, Thomas Friedman, who tells us that a fundamental reason he supports Bloomberg is because he is rich. In hisrecent pitchfor the former New York mayor, Friedman admired the fact that Bloomberg has the resources to build a machine big enough to take on the Trump machine.

This gives us an idea of Friedmans idea of utopia: It is a political system in which a person with extraordinary means can build a machine that will take over the government and then restore order by establishing the rules of behavior for the entire population. Friedman would undoubtedly counter that the purpose of the machine only concerns winning elections, but observers of modern democracy are well aware of howpolitical machineswork.

Thomas More imagined a society that didnt worship private wealth. In his Utopia, all excess wealth went into a kind of universal insurance fund. He didnt call it Medicare for all because it was about much more than health services. The society he describes didnt see money as something to be desired, but something that was useful for responding to needs: Having no use for money among themselves, but keeping it as a provision against events which seldom happen, and between which are generally long intervals, they value it no farther than it deserves, that is, in proportion to its use.

As English King Henry VIIIs chancellor, Thomas More was well aware of the relationship between money and power. He realized that if one person controls the equivalent of the monetary wealth of a nation, or simply the equivalent of the monetary wealth of a good proportion of the population, the power it confers on that person will lead inevitably to abuse, precisely because people tend to admire wealth.Embed from Getty Images

Students of history know that on July 6, 1535, More himself paid the ultimate price when he was beheaded on the orders of his boss, Henry VIII. Henry used the Protestant Reformation to seize the Catholic Churchs rich holdings and become a royal billionaire. According to Peter Ackroyd,authorof Tudors, The History of England from Henry VIII to Elizabeth I, More objected to Henrys opportunistic exploitation of the revolt against the Catholic Church principally because he saw the Reformation as a threat to the stability of society as a whole.

Moore was prescient in ways that Henry VIII was not. The Reformation inaugurated a series of devastating religious wars across Europe that lasted until the Peace of Westphalia in 1648. But More also may have underestimatedthe significance of a parallel phenomenon taking place in European politics: the emergence of the nation-state. This new form of political and social organization had begun replacing the medieval feudal order. The Reformation provided a powerful impetus toward consolidating power around nation-states.

Today, 500 years after the publication of Utopia, the global political culture built around the notion of the nation-state is under pressure. Two major factors have contributed to that pressure: the trend toward excessive militarization and the disastrous effects a global capitalist economy built around the competition of nation-states has had on the environment.

The resistance to the decline of the nation-state has now taken the form of a trend toward concentrating power in the hands of determined individuals who, by virtue of their authoritarian proclivities or their personal fortunes, can impose their personal views on the democracies that elect them. This is the age of Vladimir Putin, Donald Trump, Boris Johnson, Jair Bolsonaro, Narendra Modi, Xi Jinping, Emmanuel Macron and Victor Orban, all of whom understand how money, power, an oligarchic community of wealthy people and a media-friendly personality work together to reinforce their nations identity in competition not only with other nations, but also with other peoples (races, religions) and especially with alternative systems of social organization.

And, in some very real sense, this is all possible because billionaires not only exist but thrive inside the economies of these nation-states, even in the ones that call themselves communist.[

Peter Isackson

This article was originally published in Fair Observer

The views expressed in this article are the authors own and do not necessarily reflect Qrius editorial policy.

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Presidential Politics in the US is a Bonfire of Borough Billionaires Now - Qrius

ChildFund and Oceania Rugby announce new partnership to keep children safe in sport – sportanddev.org

The wellbeing of young people participating in sport has become an increasingly prominent concern among major sporting bodies, including the International Olympic Committee (IOC) which has recognised the risks of exploitation and abuse for children.

Through membership with World Rugby, Oceania Rugby is committed to ensuring rugby is a safe sport for all children taking part across the region.

The 'Child Safeguarding in Sport Project' was launched in December 2019, with ChildFund providing technical expertise, tools, training and support to Oceania Rugby to build child safeguarding systems in-line with international best practice.

In 2020, the project will see Oceania Rugby undertake a review of best practice and implementation of a regional framework. In addition to this, two member unions, Nauru Rugby Union and Samoa Rugby Union, will launch workshops on child safeguarding this month.

The increased focus on child safeguarding among sporting bodies has led to the emergence of important new initiatives and policies. This includes the IOC Basic Universal Principles of Good Governance, which makes it compulsory for organisations that belong to the Olympic movement to adopt these principles, implement relevant measures and monitor compliance.

Photo: ChildFund

The 'Child Safeguarding in Sport Project' builds on learning and resources developed through ChildFund Australias rugby for development program ChildFund Pass It Back.

ChildFund is considered a pioneer organisation in the development of the International Safeguards for Children in Sport and 2017 was awarded the UNICEF Safeguarding Children in Sport Award at the Beyond Sport Global Awards in recognition of its work supporting partner sporting bodies.

The over-riding objective of the project is to ensure that children engaging in rugby across the region will benefit from a safer environment both physically and emotionally.

Oceania Rugby general manager Bruce Cook said: Rugby is committed to ensuring player welfare, in all forms and at all levels of the game.

As the regional governing body of World Rugby, Oceania Rugby is committed to ensuring our game creates dynamic practices and environments where all boys and girls, men and women in our sport can thrive.

The most fundamental element to a positive sport experience is being safe physically, emotionally and socially, said Cook.

He added: Oceania Rugby is pleased to partner with ChildFund Australia. Weve worked with ChildFund Australia before and know our organisations share a commitment to achieving high-quality outcomes that are meaningful for our members and their communities.

ChildFund Pass It Back director Chris Mastaglio said: We are very proud to be partnering with Oceania Rugby on this important initiative for children.

Sport should always be a safe place for children to play, learn and grow, and Oceania Rugbys commitment to ensuring their sport is safe at all levels is to be commended.

Working in partnership with Oceania Rugby and its member unions, National Governing Bodies, the project will involve:

This article was first published by ChildFund. Visit their website for more information.

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ChildFund and Oceania Rugby announce new partnership to keep children safe in sport - sportanddev.org

GM sounds the retreat over Oceania and Thailand – just-auto.com

Holden had been reduced to a shadow of its former self, importing cars from Europe, North America and Asia and adapting global models for regional requirements

On Sunday, GM confirmed it planned to "wind down" sales, engineering and design operations in Australia and the sales anddistribution operation in New Zealandwhich, combined, employ 830 people,and "retire"the long serving Holden brand by 2021.

The company also said it had agreed to sell its Rayong plant in Thailand, which employs 1,500 people, to China's Great Wall Motors and withdraw the Chevrolet brand from that market by the end of 2020.

This is a continuation of the US automaker's policy over the last 10 years to exit markets that do not generate what it regards as adequate returns on investment.

The company sold its European Opel and Vauxhall subsidiaries to France's PSA group in 2017 and has also exited virtually all markets in Africa over the last several years.

In Asia, GM closed its plant in Indonesia in 2014 and agreed in January 2020 to sell its second plant in India, also to Great Wall Motors, having sold the other Indian plant to SAIC Motor in 2017.

The company said it planned to focus on "growth opportunities in specialty vehicle business"", no doubt referring to the huge industry wide shift that is expected to take place in the current decade towards electric vehicles (EVs) as well as growth relating to autonomous driving technologies (AV).

GM chairman and CEO Mary Barra confirmed the company is "restructuring its international operations, focusing on markets where we have the right strategies to drive robust returns, and prioritising global investments that will drive growth in the future of mobility, especially in the areas of EVs and AVs".

She added "while these (restructuring) actions support our global strategy, we understand that they impact people who have contributed so much to our company. We will support our people, our customers and our partners, to ensure an orderly and respectful transition in the impacted markets".

GM president Mark Reuss said the company had "explored a range of options to continue the Holden operationsbut none could overcome the challenges of the investments needed for the highly fragmented [global]right hand drive market, the economics to support growing the brand, and delivering an appropriate return on investment".

The company said it also carried out a "detailed analysis of the business case for future production at the Rayong manufacturing facility in Thailand. Low plant utilisation and forecast volumeshave made continued GM production at the site unsustainable. And without domestic manufacturing, Chevrolet would be unable to compete in Thailand's new vehicle market".

The company said it expected to take a US$1.1bn cash and non-cash charge this year relating to its restructuring in the three countries.

GM senior vice president and president GM International, Steve Kiefer, said GM International "is well positioned in its core markets: South America, the Middle East and South Korea. The company continues to optimise partnerships in markets like Uzbekistan, by transferring assets and building strong supply chains to reduce costs in growth markets".

Holden started full local car manufacture in Australia in 1948 and once had final assembly plants in almost every state. By the 1980s, as various government import duty and taxation measures to 'protect' local automakers from imported competition began to be reduced, it was consolidated into one large new factory at Elizabeth, a suburb of Adelaide, in South Australia, where local manufacturing ended in 2017. Many dealers subsequently lost, or quit the franchise and the company announced late in 2019 it was dumping the Commodore nameplate, dating back to 1979, and the Astra, both Opel-developed cars sourced from PSA in Europe.

Local assembly in New Zealand ended in 1990 after increasingly frictionless free trade with Australia and lowering import duty rates made the Trentham plant, built in 1967, uneconomic. GM also ended local parts production.

Australia's ABC News quoted prime minister Scott Morrison as saying he was "disappointed but not surprised" at the GM announcement.

"But I am angry, like I think many Australians would be. Australian taxpayers put millions into this multinational company. They let the brand just wither away on their watch. Now they are leaving it behind," he said.

Federal industry minister Karen Andrews said it was unacceptable for GM to have made the decision without any consultation with the government.

Holden had been whittled down to about 800 local workers with 600 focusing on design and development work for local and regional markets.

GM officials told ABC about 600 would leave by Junewhile 200 would remain in ongoing roles connected with the company's pledge to offer at least 10 more years of customer service to owners of the 1.6m Holdens in use.

Work at the Port Melbourne site would be wound down by the end of June and the [former proving ground] Lang Lang calibration facility would finish up in August.

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