Global Egg Phosphatidylcholine Market: What it got next? Find out with the latest research available at ‘The Market Reports’ – Market Research Writeup

Egg Phosphatidylcholine appear to regulate cholesterol absorption and inflammation. With an increase in old age population, the demand for egg phosphatidylcholine is expected to increase as it improves the functionality of liver thereby enhancing digestive system functioning resulting in relief to aged people.

Access Report Details at: https://www.themarketreports.com/report/global-egg-phosphatidylcholine-market-research-report

The global Egg Phosphatidylcholine market is valued at 14 million US$ in 2018 is expected to reach 22 million US$ by the end of 2025, growing at a CAGR of 5.9% during 2019-2025.

This report focuses on Egg Phosphatidylcholine volume and value at global level, regional level and company level. From a global perspective, this report represents overall Egg Phosphatidylcholine market size by analyzing historical data and future prospect. Regionally, this report focuses on several key regions: North America, Europe, China and Japan.

Key companies profiled in Egg Phosphatidylcholine Market report are Nutrasal,Avanti Polar Lipids, Lipoid, Natural Factors, Kewpie, Nof, Jena Bioscience, Vitamin Research Productsand more in term of company basic information, Product Introduction, Application, Specification, Production, Revenue, Price and Gross Margin (2014-2019), etc.

Purchase this Premium Report at: https://www.themarketreports.com/report/buy-now/1418109

Table of Content

1 Egg Phosphatidylcholine Market Overview

2 Global Egg Phosphatidylcholine Market Competition by Manufacturers

3 Global Egg Phosphatidylcholine Production Market Share by Regions

4 Global Egg Phosphatidylcholine Consumption by Regions

5 Global Egg PhosphatidylcholineProduction, Revenue, Price Trend by Type

6 Global Egg Phosphatidylcholine Market Analysis by Applications

7 Company Profiles and Key Figures in Egg Phosphatidylcholine Business

8 Egg Phosphatidylcholine Manufacturing Cost Analysis

9 Marketing Channel, Distributors and Customers

10 Market Dynamics

11 Global Egg Phosphatidylcholine Market Forecast

12 Research Findings and Conclusion

13 Methodology and Data Source

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Global Egg Phosphatidylcholine Market: What it got next? Find out with the latest research available at 'The Market Reports' - Market Research Writeup

Participants Sought for National Trial to Test Benefits of a Healthy Lifestyle – Newswise

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Newswise (CHICAGO) One-third of Americans have metabolic syndrome up from one-quarter just ten years ago and it is underdiagnosed. Metabolic syndrome is a bundle of risk factors caused by common lifestyle choices that can lead to serious conditions like diabetes, stroke, heart disease, and some types of cancer. People are considered to have metabolic syndrome if they have at least three of its five indicators central fat (waist circumference of 40 inches or more for men, 35 inches or more for women), high blood pressure, high blood sugar, low HDL cholesterol, and elevated triglycerides.

The EnhancedLifestyles forMetabolic Syndrome (ELM) Trial, a multisite test of two lifestyle treatments for a dangerous cluster of sub-disease indicators called the metabolic syndrome, is now accepting applicants at five medical centers around the country.

Over the next two years, with funding from the William G. McGowan Charitable Fund, the ELM Trial, developed at Rush University Medical Center in Chicago, Illinois, aims to enroll 600 people who are at high-risk for chronic disease and are interested in managing this risk by optimizing their lifestyle. The partner sites are Rush in Chicago, Illinois; University of Colorado Denver, Denver, Colorado; Geisinger Health System, Wilkes-Barre/Scranton, Pennsylvania; Rochester Institute of Technology, Rochester, New York; and University of Missouri - Kansas City, Kansas City, Missouri.

"We need to see which approach is better at achieving a sustained remission in metabolic syndrome with lifestyle changes," says Lynda Powell PhD, MEd, preventive medicine chair at Rush Medical College, and the Principal Investigator of the ELM trial.

Until the serious medical conditions the syndrome causes emerge, these people may not feel ill. Different drugs are available to address the syndrome's markers, like anti-hypertension medication, but none of these drugs treat the underlying lifestyle cause of the syndrome.

The good news is that better lifestyle choices, like the ones ELM teaches, have repeatedly been associated with low risk for the metabolic syndrome along with low risk for the diseases it portends.

"We know that lifestyle change works," says Jennifer Ventrelle MS, a registered nutritionist and director of the ELM Lifestyle Program at the Rush University Prevention Center. Ventrelle, who is charged with making sure the ELM Intervention is administered consistently across all the participating centers, cites the Diabetes Prevention Program as one solid trial that showed the importance of lifestyle change on health.

The process is not always easy, though. "We know how to get people to change their behavior in the short term to eat better, be active, or stop smoking. The challenge is to get these changes to stick over time," Powell says.

For this trial, the first thirty eligible candidates will embark on the evidence-based ELM program at each of the five sites in January of 2020; signups will continue through spring of 2021. Participants will engage in the program for six months, and then will be followed for an additional 18 months, to allow for an assessment of how well they have been able to sustain the good habits they developed, and the health benefits they received.

The ELM program provides tools, methods and support for healthier eating, increased physical activity and stress management. Guidelines include making vegetables half of every lunch and dinner, exercising for at least 30 minutes on most days, and learning to be less reactive to stressors.

The Rush team has been studying a group-based version of ELM for nearly a decade. A "self-directed" option representing the best lifestyle information available in clinical practice today will be compared to the group-based program. Participants in both programs will receive a Fitbit to help them monitor their physical activity.

A condition of enrollment is a willingness to participate in either arm of the trial. Participants will not get to choose. The group approach, which has been shown to be effective, requires participants to attend meetings. While those can be helpful, they're time-consuming and may be inconvenient; from a public-health standpoint, groups are expensive and labor-intensive.

"Can we simplify this treatment?" Powell asks. Can participants get the same or better health results under their own direction, with only minimal contact with the program? That's an important question investigators hope to answer. "We truly don't know which one is better," Powell says.

Everyone in the self-directed arm will be assigned to a coordinator, and will receive a Fitbit activity tracker, access to the program's website, and monthly tip sheets for six months.

"They'll get the best lifestyle protocols we have in medical practice today, augmented by one of the best wearables (the Fitbit)," Powell says.

In the group-based program, participants will get most of those things, too. But instead of the tip sheet, group members will meet for an hour and a half weekly for three months, biweekly for an additional three months, and monthly for 18 months after that. They will also have access to the ELM website. They will learn, for example, to distinguish when they are eating because they are hungry from when they turn to food because it is available or they are bored or sad.

Participants in both arms of the program will report for three follow-up visits so their progress can be assessed. They will receive lab results and physical measures after each visit.

Not everybody with metabolic syndrome is interested in eating a healthier diet and undertaking a regular exercise program, but many people are. Powell says ELM can give those people a boost on their journey.

"We try to get people to see that living a healthy lifestyle is all about enjoying life, and having more energy and vitality," Powell says.

Anyone older than 18 who has three of the five markers for metabolic syndrome, does not have diabetes, can converse in English, and is committed to making healthy lifestyle changes, can apply to participate in the ELM Trial at one of its five sites. For more information, go to http://www.elmtrial.org.

To apply at Rush in Chicago, emailELMTrial@rush.edu, orcall Dan Lindich (312) 563-3756 or Joselyn Williams (312) 563-8790.

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Participants Sought for National Trial to Test Benefits of a Healthy Lifestyle - Newswise

Men and women subtly see their own health differently – Ladders

How secure you feel about your ability to keeping up good health habits and routines can depend on your gender, according to aMayo Clinic study published in the American Journal of Health Behavior.By surveying the members of a little-used employee wellness center, Mayo Clinic researchers were able to discern subtle ways that men and women saw their own health differently.

The study surveyed 2,784 users at the Mayo Clinic Dan Abraham Healthy Living Center, an employee wellness center.

Our findings suggest that confidence in maintaining healthy habits can be influenced by gender and also depends on which specific habit is being assessed physical activity, for example, versus diet, says Richa Sood, M.D., a Mayo Clinic internist, co-author and designer of the study, said in a release.This is important information to keep in mind when designing wellness programs, to maximize their utilization and impact on employee health and wellness.

There has been some pushback about employee wellness centers recently, both in the media and in the research world. Back in April, a major study among warehouse workers found that workplace wellness programs may not be so beneficial after all offering no real effects on health outcomes.

Researchers wanted to learn about the under-utilization of employee wellness centers, and any possible gender-specific reasons why. They began by distributing 11,427 surveys to those wellness centers, and 2,784 completed surveys came back. Of those, 68% were women, and the average age across genders was 49.

The survey questions about users health status and health conditions, their confidence in keeping up healthy habits, their stress levels, and social life. Men and women reported comparable levels of stress, and they both reported to be in favor of healthy living, according to the study. More men reported having hypertension, diabetes, high cholesterol and tobacco use than women. However, there was no significant gender difference in the perception of personal health.

There were some differences, although at first glance the men and women respondents seemed fairly similar.

We were surprised by the finding that men felt they were as healthy as women despite having more medical problems, Dr. Sood says.

Women had lower self-reported levels of physical activity and felt less confident that they would keep up their exercise.

This difference may have cultural roots because gender has been shown to influence self-efficacy, particularly for physical activity, said Dr. Sood. (Psychologist Albert Bandura has defined self-efficacy as ones belief in ones ability to succeed in specific situations or accomplish a task.) Self-efficacy is not a gender-specific trait, said Dr. Sood. Still, understanding gender differences among working adults can help optimize employee wellness services.

In general, employee wellness centers across the country remain underused, despite their status as an $8 billion industry.

I am personally not convinced that lunchtime yoga and mason jars of trail mix are the antidotes to our global epidemic of workplace stress and burnout, wrote Charlotte Lieberman in the Harvard Business Review. For all the attention (and money spent) on workplace wellness, the jury is still out on whether these programs are really beneficial to our health.

Amit Sood, M.D., a study co-author, owns the Global Center for Resilience and Wellbeing. Dr. Richa Sood is his spouse. Other authors reported no conflicts of interest or financial disclosures.

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Men and women subtly see their own health differently - Ladders

At CIIE 2019 Panasonic Showcases Solutions to Help Bring to Life China’s "Healthy China 2030" Vision – Business Wire

SHANGHAI--(BUSINESS WIRE)--Panasonic Corporation took part in the 2nd China International Import Expo (CIIE) 2019, which was held in Shanghai from November 5 to 10.Under the theme, "Limitless Care for Healthy Living," Panasonic showcased health and welfare products and solutions that reflect its unique health values. With these products and solutions for a healthy life and aging society, Panasonic aspires to help bring to life China's "Healthy China 2030" vision. Panasonic also introduced its cutting-edge technologies that contribute to the business scene.

[Video] #CIIE 2019 Panasonic Highlights - The 2nd China International Import Expo https://youtu.be/CbvZClNirQc

Panasonic Booth HighlightsSolutions for a Healthy Life and an Aging Society1. "Healthy Environment Unit"With the evolution of sensing and data analytics technology, spaces and devices will be able to sense the changes your body undergoes, and make suggestions that will help you enjoy a healthy lifestyle. In the "vital sensing bedroom," a comfortable sleeping environment will be created with sensors that analyze your heartbeat, number of breaths taken, how many times you turned in bed and AI that optimally controls the lighting, temperature, humidity, and scent based on past data.

In the bathroom, the "Vital Sensing Toilet" will take your heartbeat and blood pressure measurements and utilize AI to determine your stress level and make suggestions to help you relax. And when using the sink, the "Smart Mirror" will measure your weight and body-fat percentage to introduce menus and physical training methods best suited to your physical condition.

[Video] For Healthy Life - Panasonic #CIIE 2019 https://youtu.be/TGiYXZDv5BU

2. "Barrier Free Villa"Panasonic proposed compact, highly-functional and stylish renovation ideas that help the elderly live independently by alleviating their burden. Examples of bedroom environment renovations featuring Made in Japan solutions that are really well thought through, and elderly-friendly products for care facilities such as electronic beds, lighting, etc. were showcased.

Moreover, the elderly may not be as confident about their walking as they had been before. "Walking training robots" introduced at the exhibition are equipped with AI-enabled control technology that automatically analyzes the walking ability of the user and provides appropriate walking training with the optimal physical load to help elderly remain independent.

[Video] For Aging Society - Panasonic #CIIE 2019 https://youtu.be/e23n882OcdM

3. "Healthy and Comfortable LDK Environment"In the comfortable LDK environment where users can have easy access to information about their health and how they may better manage it, Panasonic showcased its transparent OLED, which blends into the interior and creates the environment optimal for the family's health or for the scene as well as a mock sky window that adds brightness and openness to the space and a kitchen with ample storage and ingenious hacks for chores.

[Video] For Living, Dining & Kitchen - Panasonic #CIIE 2019 https://youtu.be/I4kYSBpQbPw

4. "Food Safety and Security"Utilizing cutting-edge technologies accumulated to date, Panasonic proposed an end-to-end solution ranging from food production, precooling warehousing systems, low temperature transport, and refrigerated warehouses.

5. "Air Quality"This section introduced and demonstrated solutions that deliver excellent air quality for both homes and centrally cooled/heated facilities.

[Video] For Air Quality - Panasonic #CIIE 2019 https://youtu.be/AVqtYIQXt3E

6. "Home Appliances"In the "Cooking" area, Panasonic introduce a tajine pot that lets you cook without water, a 3-in-1 oven range that can steam and bake in a short length of time, partial freezing and nanoe technologies, as well as a compact-big, large capacity refrigerator. With respect to "Beauty," Panasonic introduced its high end X series including its unique drier that moisturizes hair and makes it silky smooth, ion effector that moisturizes skin from the keratinous layer with high molecular osmosis, and a RF facial massager to make skin nice and firm.

[Video] Beauty Product - Panasonic #CIIE 2019 https://youtu.be/nEnp3BiKrTM

Advanced Technology1. "Pure Hydrogen Fuel Cell"From building energy consuming towns to new, sustainable towns. Panasonic introduced the pure hydrogen fuel cell, which supplies energy generated by utilizing hydrogen created from renewable energy.

2. "Potential for Reuse, Industrialized Housing"Improving the lives of 60 million people who work on construction sites is an important social issue in China. Panasonic proposed solutions developed with its business partners that are capable of providing temporary housing quickly to these construction sites, temporary medical care and event venues.

3. "Data Archiver"This scalable disc library solution can store the ever expanding volume of data over long periods of time. It is a high capacity data recording device that can store petabytes (PB) to exabytes (EX) of big data or video content.

4. "Media Integration Studio Solution"This advanced media integration solution will reinvent the TV program production process.

5. "Spatial Presentation Solution"The 360-degree projector and human sensors work together to create a truly immersive viewing experience.

6. "Factory Automation"Panasonic introduced solutions that can optimize every area in the factory and contribute to factory automation and personnel savings.

7. "Filing Management Solution"Equipped with a high performance scanning technology, this filing management solution is optimal for governments, as well as financial institutions and educational facilities.

8. "Let's Note/Toughbook"Panasonic showcased its state-of-the-art products that help improve efficiency at work sites.

9. "Olympic and Paralympic Games"This section introduced Panasonic's history and category as the Worldwide Partner of the Olympic and Paralympic Games.

[Video] Business Solutions & Advanced Technology - Panasonic #CIIE 2019 https://youtu.be/uHYgl6E8opQ [Video] Sponsorship Activity - Panasonic #CIIE 2019 https://youtu.be/_XRwrccwU_s

Panasonic Booth OverviewPeriod: November 5 (Tue) - 10 (Sun), 2019Location: National Exhibition and Convention Center (Shanghai) 5.1H B4Floor space: 1,004 m2Exhibition theme: "Placing customers first, always - for a happy mind, happy body"Content: Health and welfare solutions, cutting-edge technologies

CIIE 2019 Panasonic Official Website (Chinese)https://panasonic.cn/about/brand-story/CIIE2019/ Here you will find a description of the Panasonic booth, what the venue was like during the exhibition, media coverage, as well as other information about CIIE 2019.https://panasonic.cn/cna/healthy-life (Chinese)Panasonic is introducing a wide range of content about its health and welfare business, including interviews with experts from various fields such as construction, medical, beauty, psychology, etc.

About PanasonicPanasonic Corporation is a worldwide leader in the development of diverse electronics technologies and solutions for customers in the consumer electronics, housing, automotive, and B2B businesses. The company, which celebrated its 100th anniversary in 2018, has expanded globally and now operates 582 subsidiaries and 87 associated companies worldwide, recording consolidated net sales of 8.003 trillion yen for the year ended March 31, 2019. Committed to pursuing new value through innovation across divisional lines, the company uses its technologies to create a better life and a better world for its customers. To learn more about Panasonic: https://www.panasonic.com/global.

Source: https://news.panasonic.com/global/topics/2019/73428.html

Related Links[Video Playlist] CIIE 2019 - The 2nd China International Import Expohttps://www.youtube.com/playlist?list=PLE29Nx-sjAHCHgH713KEk-Z8gwnZ4She1

[Photo Album] Panasonic booth at CIIE 2019https://gallery.vphotos.cn/vphotosgallery/index.html?vphotowechatid=109103D1AFC848E0E59B4EC17204D3E3&gallery_source_code=0&from=groupmessage&isappinstalled=0&gallery_source_code=0#/gallerypc

Panasonic China (Chinese)http://www.panasonic.cn/

China International Import Expo (CIIE) - Panasonic Major Exhibitionhttps://www.panasonic.com/global/corporate/exhibition/en/ciie_2019.html

CIIE 2019 Panasonic Official Website (Chinese)https://panasonic.cn/about/brand-story/CIIE2019/

China International Import Expohttps://www.ciie.org/zbh/en/

Panasonic Opens Its 3rd Brand Center in the World in Hangzhou to Create a New Story of Beautiful Dreams (Oct 25, 2019)https://news.panasonic.com/global/topics/2019/72467.html

Panasonic to Exhibit Digital Technology and Products for Smart Factory at CIIF 2019 (Sep 13, 2019)https://news.panasonic.com/global/topics/2019/71801.html

Panasonic Stages Intelligent Living Space at KBC 2019 (Jun 10, 2019)https://news.panasonic.com/global/topics/2019/69105.html

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At CIIE 2019 Panasonic Showcases Solutions to Help Bring to Life China's "Healthy China 2030" Vision - Business Wire

How to Make the Most of Your Old Tech – New York Magazine

Photo: Billy H.C. Kwok/Bloomberg via Getty Images

If youre the kind of tech person who likes to stay on the cutting edge, the kind who upgrades their phone every year or rotates laptops with a significant frequency, then it can be tough to know what you should do with your old stuff. I mean, yeah, you could throw it out or try to sell it on eBay, but you can also put it to work in other useful ways. Here are some ideas.

Remote control

A lot of people, myself included, use their phones to control their TV and stereo. You can cast stuff video to your TV or music to a smart speaker via functions like Airplay or Chromecast. If you want to unplug and put your smartphone away when youre at home, having a separate device for a remote control is extremely helpful.

Gaming

Yeah, smartphones are good for mobile games, but theres some cool stuff on the horizon as well. Companies like Google and Microsoft are working on cloud gaming, letting you (theoretically) play console-quality games on your phone by streaming video from a remote server. Newer Android phones and iPhones with iOS 13 are compatible with Xbox and PlayStation controllers, so its worth keeping an old smartphone around if youre interested in checking it out.

Webcam

If youre worried about security but not worried enough to buy a dedicated camera, you can use an old Android phone instead. Most guides recommend an app called IP Webcam to get it working. Once its set up, you can check in on things while youre out.

Spare GPS device

Even if you dont have an internet connection, your old smartphones GPS system should still work. Popular apps like Google Maps let you cache navigational data and save it offline, so theres nothing stopping you from keep an old phone in your car just in case.

PC media server

Instead of junking your old PC, set it up as a media server (heres a tutorial) so you can access movies, music, and family photos from any device on your network. It makes it easier to share stuff with your household without manually sending files around.

Participate in a science project

Folding@home is a distributed computing project that simulates protein folding, computational drug design, and other types of molecular dynamics. Its a program that runs in the background on computers and aids medical research. Is your old PC going to cure cancer? Probably not. But itll help in a small way.

Strip it for parts

This is a long shot but theres a healthy aftermarket for old PC parts, in part because you cant really buy individual components directly from manufacturers. You can also do it just to see if you can. iFixIt sells plenty of ready-made kits for any assembly/disassembly project you might pursue.

Give it to your parents

This ones pretty obvious but you can save yourself some time and headaches by taking an old computer or phone, setting it up yourself, and then giving it to your parents. Theyre not going to replace that old Gateway on their own!

Paperweight

When the electrical grid eventually fails and we return to using paper for everything, youre gonna need something to hold all of that paper down.

Daily news about the politics, business, and technology shaping our world.

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How to Make the Most of Your Old Tech - New York Magazine

Argonne Researchers to Share Scientific Computing Insights at SC19 – HPCwire

Nov. 15, 2019 The Supercomputing 2019 (SC19) conference, scheduled for November 1722 in Denver, will bring together the global high-performance computing (HPC) community, including researchers from the U.S. Department of Energys (DOE) Argonne National Laboratory, to share scientific computing advances and insights with an eye toward the upcoming exascale era.

Continuing the laboratorys long history of participation in the SC conference series, more than 90 Argonne researchers will contribute to conference activities and studies on topics ranging from exascale computing and big data analysis to artificial intelligence (AI) and quantum computing.

SC is a tremendous venue for Argonne to showcase its innovative uses of high-performance and data-intensive computing to advance science and engineering, said Salman Habib, director of Argonnes Computational Science division. We look forward to sharing our research and connecting with and learning from our peers, who are also working to push the boundaries of extreme-scale computing in new directions.

As the future home to one of the worlds first exascale supercomputers Aurora, an Intel-Cray machine scheduled to arrive in 2021 Argonne continues to drive the development of technologies, tools and techniques that enable scientific breakthroughs on current and future HPC systems. To fully realize exascales potential, the laboratory is creating an environment that supports the convergence of AI, machine learning and data science methods alongside traditional modeling and simulation-based research.

We are seeing rapid advances in the application of deep learning and other forms of AI to complex science problems at Argonne and across the broader research community, said Ian Foster, director of Argonnes Data Science and Learning division, Argonne Distinguished Fellow and also the Arthur Holly Compton Distinguished Service Professor of Computer Science at the University of Chicago. SC provides a forum for the community to get together and share how these methods are being used to accelerate research for a diverse set of applications.

The laboratorys conference activities will include technical paper presentations, talks, workshops, birds of a feather sessions, panel discussions and tutorials. In addition, Argonne will partner with other DOE national laboratories to deliver talks and demos at the DOEs conference booth (#925). Some notable Argonne activities are highlighted below. For the full schedule of the laboratorys participation in the conference, visitArgonnes SC19 webpage.

DOE Booth Talk: Scientific Domain-Informed Machine Learning

Argonne computer scientist Prasanna Balaprakash will delivera talk at the DOE boothon the laboratorys pivotal research with machine learning. His featured talk will cover Argonnes efforts to develop and apply machine learning approaches that enable data-driven discoveries in a wide variety of scientific domains, including cosmology, cancer research and climate modeling. Balaprakash will highlight successful use cases across the laboratory, as well as some exciting avenues for future research.

In Situ Analysis for Extreme-Scale Cosmological Simulations

Argonne physicist and computational scientist Katrin Heitmann will deliver thekeynote talkat the In Situ Infrastructures for Enabling Extreme-scale Analysis and Visualization (ISAV 2019) workshop. Her talk will cover the development of in situ analysis capabilities (i.e., data analysis while a simulation is in progress) for the Hardware/Hybrid Accelerated Cosmology Code, which has been used to carry out several extreme-scale simulations on DOE supercomputers. Heitmann will discuss the current limitations of her teams on the fly analysis tool suite and how they are developing solutions to prepare for the arrival of DOEs forthcoming exascale systems.

Full-State Quantum Circuit Simulation by Using Data Compression

Researchers from Argonne and the University of Chicago will present atechnical paperon their work to develop a new quantum circuit simulation technique that leverages data compression, trading computation time and fidelity to reduce the memory requirements of full-state quantum circuit simulations. Demonstrated on Argonnes Theta supercomputer, the teams novel approach provides researchers and developers with a platform for quantum software debugging and hardware validation for modern quantum devices that have more than 50 qubits.

Deep Learning on Supercomputers

Argonne scientists will have a strong presence at the Deep Learning on Supercomputers workshop. Co-chaired by Foster, the workshop provides a forum for researchers working at the intersection of deep learning and HPC. Argonne researchers are part of a multi-institutional team that will present DeepDriveMD: Deep-Learning-Driven Adaptive Molecular Simulations for Protein Folding. The study provides a quantitative basis by which to understand how coupling deep learning approaches to molecular dynamics simulations can lead to effective performance gains and reduced times-to-solution on supercomputing resources.

A team of researchers from Argonne and the University of Chicago will present Scaling Distributed Training of Flood-Filling Networks on HPC Infrastructure for Brain Mapping at the Deep Learning on Supercomputers workshop. The teams paper details an approach to improve the performance of flood-filling networks, an automated method for segmenting brain data from electron microscopy experiments. Using Argonnes Theta supercomputer, the researchers implemented a new synchronous and data-parallel distributed training scheme that reduced the amount of time required to train the flood-filling network.

Priority Research Directions for In Situ Data Management: Enabling Scientific Discovery from Diverse Data Sources

At the 14th Workshop on Workflows in Support of Large-Scale Science (WORKS19), Argonne computer scientist Tom Peterkaskeynote talkwill cover six priority research directions that highlight the components and capabilities needed for in situ data management to be successful for a wide variety of applications. In situ analysis tools can enable discoveries from a broad range of data sources HPC simulations, experiments, scientific instruments and sensor networks by helping researchers minimize data movement, save storage space and boost resource efficiency, often while simultaneously increasing scientific precision.

The Many Faces of Instrumentation: Debugging and Better Performance using LLVM in HPC

Argonne computational scientist Hal Finkel will deliver a keynote talk on the open-source LLVM compiler infrastructure at theWorkshop on Programming and Performance Visualization Tools (ProTools 19). LLVM, winner of the 2012 ACM Software System Award, has become an integral part of the software-development ecosystem for optimizing compilers, dynamic-language execution engines, source-code analysis and transformation tools, debuggers and linkers, and a host of other programming language- and toolchain-related components. Finkel will discuss various LLVM technologies, HPC tooling use cases, challenges in using these technologies in HPC environments, and interesting opportunities for the future.

About Argonne National Laboratory

Argonne National Laboratoryseeks solutions to pressing national problems in science and technology. The nations first national laboratory, Argonne conducts leading-edge basic and applied scientific research in virtually every scientific discipline. Argonne researchers work closely with researchers from hundreds of companies, universities, and federal, state and municipal agencies to help them solve their specific problems, advance Americas scientific leadership and prepare the nation for a better future. With employees from more than 60 nations, Argonne is managed byUChicago Argonne, LLCfor theU.S. Department of Energys Office of Science.

About the U.S. Department of Energys Office of Science

The U.S. Department of Energys Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time. For more information, visit https://energy.gov/science

Source: Jim Collins, Argonne National Laboratory

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Argonne Researchers to Share Scientific Computing Insights at SC19 - HPCwire

That Junk DNA Is Full of Information! – Advanced Science News

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It should not surprise us that even in parts of the genome where we dont obviously see a functional code (i.e., one thats been evolutionarily fixed as a result of some selective advantage), there is a type of code, but not like anything weve previously considered as such. And what if it were doing something in three dimensions as well as the two dimensions of the ATGC code? A paper just published in BioEssays explores this tantalizing possibility

Isnt it wonderful to have a really perplexing problem to gnaw on, one that generates almost endless potential explanations. How about what is all that non-coding DNA doing in genomes?that 98.5% of human genetic material that doesnt produce proteins. To be fair, the deciphering of non-coding DNA is making great strides via the identification of sequences that are transcribed into RNAs that modulate gene expression, may be passed on transgenerationally (epigenetics) or set the gene expression program of a stem cell or specific tissue cell. Massive amounts of repeat sequences (remnants of ancient retroviruses) have been found in many genomes, and again, these dont code for protein, but at least there are credible models for what theyre doing in evolutionary terms (ranging from genomic parasitism to symbiosis and even exploitation by the very host genome for producing the genetic diversity on which evolution works); incidentally, some non-coding DNA makes RNAs that silence these retroviral sequences, and retroviral ingression into genomes is believed to have been the selective pressure for the evolution of RNA interference (so-called RNAi); repetitive elements of various named types and tandem repeats abound; introns (many of which contain the aforementioned types of non-coding sequences) have transpired to be crucial in gene expression and regulation, most strikingly via alternative splicing of the coding segments that they separate.

Still, theres plenty of problem to gnaw on because although we are increasingly understanding the nature and origin of much of the non-coding genome and are making major inroads into its function (defined here as evolutionarily selected, advantageous effect on the host organism), were far from explaining it all, andmore to the pointwere looking at it with a very low-magnification lens, so to speak. One of the intriguing things about DNA sequences is that a single sequence can encode more than one piece of information depending on what is reading it and in which direction viral genomes are classic examples in which genes read in one direction to produce a given protein overlap with one or more genes read in the opposite direction (i.e., from the complementary strand of DNA) to produce different proteins. Its a bit like making simple messages with reverse-pair words (a so-called emordnilap). For example: REEDSTOPSFLOW, which, by an imaginary reading device, could be divided into REED STOPS FLOW. Read backwards, it would give WOLF SPOTS DEER.

Now, if it is of evolutionary advantage for two messages to be coded so economically as is the case in viral genomes, which tend to evolve towards minimum complexity in terms of information content, hence reducing necessary resources for reproductionthen the messages themselves evolve with a high degree of constraint. What does this mean? Well, we could word our original example message as RUSH-STEM IMPEDES CURRENT, which would embody the same essential information as REED STOPS FLOW. However, that message, if read in reverse (or even in the same sense, but in different chunks) does not encode anything additional that is particularly meaningful. Probably the only way of conveying both pieces of information in the original messages simultaneously is the very wording REEDSTOPSFLOW: thats a highly constrained system! Indeed, if we studied enough examples of reverse-pair phrases in English, we would see that they are, on the whole, made up of rather short words, and the sequences are missing certain units of language such as articles (the, a); if we looked more closely, we might even detect a greater representation than average of certain letters of the alphabet in such messages. We would see these as biases in word and letter usage that would, a priori, allow us to have a stab at identifying such dual-function pieces of information.

Now lets return to the letters, words, and information encoded in genomes. For two distinct pieces of information to be encoded in the same piece of genetic sequence we would, similarly, expect the constraints to be manifest in biases of word and letter usagethe analogies, respectively, for amino acid sequences constituting proteins, and their three-letter code. Hence a sequence of DNA can code for a protein and, in addition, for something else. This something else, according to Giorgio Bernardi, is information that directs the packaging of the enormous length of DNA in a cell into the relatively tiny nucleus. Primarily it is the code that guides the binding of the DNA-packaging proteins known as histones. Bernardi refers to this as the genomic codea structural code that defines the shape and compaction of DNA into the highly-condensed form known as chromatin.

But didnt we start with an explanation for non-coding DNA, not protein-coding sequences? Yes, and in the long stretches of non-coding DNA we see information in excess of mere repeats, tandem repeats and remnants of ancient retroviruses: there is a type of code at the level of preference for the GC pair of chemical DNA bases compared with AT. As Bernardi reviews, synthesizing his and others groundbreaking work, in the core sequences of the eukaryotic genome, the GC content in structural organizational units of the genome termed isochores increased during the evolutionary transition between so-called cold-blooded and warm-blooded organisms. And, fascinatingly, this sequence bias overlaps with sequences that are much more constrained in function: these are the very protein-coding sequences mentioned earlier, and theymore than the intervening non-coding sequencesare the clue to the genomic code.

Protein-coding sequences are also packed and condensed in the nucleus particularly when theyre not in use (i.e., being transcribed, and then translated into protein) but they also contain relatively constant information on precise amino acid identities, otherwise they would fail to encode proteins correctly: evolution would act on such mutations in a highly negative manner, making them extremely unlikely to persist and be visible to us. But the amino acid code in DNA has a little catch that evolved in the most simple of unicellular organisms (bacteria and archaea) billions of years ago: the code is partly redundant. For example, the amino acid Threonine can be coded in eukaryotic DNA in no fewer than four ways: ACT, ACC, ACA or ACG. The third letter is variable and hence available for the coding of extra information. This is exactly what happens to produce the genomic code, in this case creating a bias for the ACC and ACG forms in warm-blooded organisms. Hence, the high constraint on this additional codewhich is also seen in parts of the genome that are not under such constraint as protein-coding sequencesis imposed by the packaging of protein-coding sequences that embody two sets of information simultaneously. This is analogous to our example of the highly-constrained dual-information sequence REEDSTOPSFLOW.

Importantly, however, the constraint is not as strict as in our English language example because of the redundancy of the third position of the triplet code for amino acids: a better analogy would be SHE*ATE*STU* where the asterisk stands for a variable letter that doesnt make any difference to the machine that reads the three-letter component of the four-letter message. One could then imagine a second level of information formed by adding D at these asterisk points, to make SHEDATEDSTUD (SHE DATED STUD). Next imagine a second reading machine that looks for meaningful phrases of a sensitive nature containing a greater than average concentration of Ds. This reading machine carries a folding machine with it that places a kind of peg at each D, kinking the message by 120 degrees in a plane. a point where the message should be bent by 120 degrees in the same plane, we would end up with a more compact, triangular, version. In eukaryotic genomes, the GC sequence bias proposed to be responsible for structural condensation extends into non-coding sequences, some of which have identified activities, though less constrained in sequence than protein-coding DNA. There it directs their condensation via histone-containing nucleosomes to form chromatin.

Figure. Analogy between condensation of a word-based message and condensation of genomic DNA in the cell nucleus. Panel A: Information within information, a sequence of words with a variable fourth space which, when filled with particular letters, generates a further message. One message is read by a three-letter reading machine; the other by a reading machine that can interpret information extending to the 4thvariableposition of the sequence. The second reader recognizes sensitive information that should be concealed, and at the points where a D appears in the 4th position, it folds the string of words, hence compressing the sensitive part and taking it out of view. This is an analogy for the principle of genomic 3D compression via chromatin, as depicted in panel B: a fluorescence image (via Fluorescence In-Situ Hybridization FISH) of the cell nucleus. H2/H3 isochores, which increased in GC content during evolution from cold-blooded to warm-blooded vertebrates, are compressed into a chromatin core, leaving L1 isochores (with lower GC content) at the periphery in a less-condensed state. The genomic code embodied in the high-GC tracts of the genome is, according to Bernardi [1], read by the nucleosome-positioning machinery of the cell and interpreted as sequence to be highly compressed in euchromatin. Acknowledgements: Panel A: concept and figure production: Andrew Moore; Panel B: A FISH pattern of H2/H3 and L1 isochores from a lymphocyte induced by PHAcourtesy of S. Sacconeas reproduced in Ref. [1].]

These regions of DNA may then be regarded as structurally important elements in forming the correct shape and separation of condensed coding sequences in the genome, regardless of any other possible function that those non-coding sequences have: in essence, this would be an explanation for the persistence in genomes of sequences to which no function (in terms of evolutionarily-selected activity), can be ascribed (or, at least, no substantial function).

A final analogythis time much more closely relatedmight be the very amino acid sequences in large proteins, which do a variety of twists, turns, folds etc. We may marvel at such complicated structures and ask but do they need to be quite so complicated for their function? Well, maybe they do in order to condense and position parts of the protein in the exact orientation and place that generates the three-dimensional structure that has been successfully selected by evolution. But with a knowledge that the genomic code overlaps protein coding sequences, we might even start to become suspicious that there is another selective pressure at work as well

Andrew Moore, Ph.D.Editor-in-Chief, BioEssays

Reference:

1. G.Bernardi. 2019. The genomic code: a pervasive encoding/moulding ofchromatin structures and a solution of the non-coding DNA mystery. BioEssays41:12. 1900106

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That Junk DNA Is Full of Information! - Advanced Science News

Interpace to Host Conference Call and Webcast to Discuss Third Quarter 2019 Financial Results on Wednesday, November 13, 2019 – Yahoo Finance

PARSIPPANY, NJ, Nov. 12, 2019 (GLOBE NEWSWIRE) -- Interpace (IDXG) announced today that it will report its third quarter 2019 financial results on Wednesday, November 13, 2019 at 4:30 p.m. ET. Interpace will host a conference call and webcast to discuss the Companys financial results and provide a general business update.

All listeners should confirm they are dialing in for the Interpace conference call with the operator who will promptly place them into the call. A webcast replay will be available on the companys website (www.interpacediagnostics.com) approximately two hours following completion of the call and will be archived on the companys website for 90 days.

About Interpace, Inc.

Interpace is a leader in enabling personalized medicine, offering specialized services along the therapeutic value chain from early diagnosis and prognostic planning to targeted therapeutic applications.

Interpaces Diagnostic Business is a fully integrated commercial and bioinformatics business unit that provides clinically useful molecular diagnostic tests, bioinformatics and pathology services for evaluating risk of cancer by leveraging the latest technology in personalized medicine for improved patient diagnosis and management. Interpace has four commercialized molecular tests and one test in a clinical evaluation process (CEP): PancraGEN for the diagnosis and prognosis of pancreatic cancer from pancreatic cysts; ThyGeNEXT for the diagnosis of thyroid cancer from thyroid nodules utilizing a next generation sequencing assay; ThyraMIR for the diagnosis of thyroid cancer from thyroid nodules utilizing a proprietary gene expression assay; and RespriDXthat differentiates lung cancer of primary vs. metastatic origin. In addition, BarreGEN for Barretts Esophagus, is currently in a clinical evaluation program whereby we gather information from physicians using BarreGEN to assist us in positioning the product for full launch, partnering and potentially supporting reimbursement with payers.

Interpaces Biopharma Business is a market leader in providing pharmacogenomics testing, genotyping, and biorepository services to the pharmaceutical and biotech industries. The Biopharma Business also advances personalized medicine by partnering with pharmaceutical, academic, and technology leaders to effectively integrate pharmacogenomics into their drug development and clinical trial programs with the goals of delivering safer, more effective drugs to market more quickly, and improving patient care.

For more information, please visit Interpaces website at http://www.interpacediagnostics.com.

Forward-looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995, relating to the Company's future financial and operating performance. The Company has attempted to identify forward looking statements by terminology including "believes," "estimates," "anticipates," "expects," "plans," "projects," "intends," "potential," "may," "could," "might," "will," "should," "approximately" or other words that convey uncertainty of future events or outcomes to identify these forward-looking statements. These statements are based on current expectations, assumptions and uncertainties involving judgments about, among other things, future economic, competitive and market conditions and future business decisions, all of which are difficult or impossible to predict accurately and many of which are beyond the Company's control. These statements also involve known and unknown risks, uncertainties and other factors that may cause the Company's actual results to be materially different from those expressed or implied by any forward-looking statement. Additionally, all forward-looking statements are subject to the Risk Factors detailed from time to time in the Company's most recent Annual Report on Form 10-K and Quarterly Reports on Form 10Q. Because of these and other risks, uncertainties and assumptions, undue reliance should not be placed on these forward-looking statements. In addition, these statements speak only as of the date of this press release and, except as may be required by law, the Company undertakes no obligation to revise or update publicly any forward-looking statements for any reason.

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CONTACTS:Investor Relations - Edison GroupJoseph Green(646) 653-7030jgreen@edisongroup.com

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Interpace to Host Conference Call and Webcast to Discuss Third Quarter 2019 Financial Results on Wednesday, November 13, 2019 - Yahoo Finance

Genealogy Products and Services Market Demand for Genetic Testing to Surge as Preventive Healthcare and Pharmacogenomics Gain Traction – Young…

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Genealogy Products and Services Market Demand for Genetic Testing to Surge as Preventive Healthcare and Pharmacogenomics Gain Traction - Young...

3 misconceptions undergrads have about applying to med school – American Medical Association

If youre applying to medical school, or even considering it, you should approach the process with all the essential information. There are some assumptions that youll findonce you get into your researchjust dont hold up.

A recent series of episodes in the AMAs Making the Rounds podcast examine medical school admissions and shed light on some myths surrounding the process. In the episodes, experts from medical school admissions consultancy MedSchoolCoach LLC, discuss some of the common misconceptions premeds hold about the application process.

Science majors are more common, but many admissions offices value well-rounded students who follow their passions.

I thought going into my undergraduate that I had to pick one of those hard science majors, said Kathryn Henshaw, a Medical College Admissions Test (MCAT) coach at MedSchoolCoach who earned her bachelors degree from the University of Miami in 2018.

I ended up picking two of those, Henshaw said. I've studied biochemistry and neuroscience, but I really wish I had studied creative writing and that's one of my biggest regrets is not realizing that I could have studied creative writing and written poemswhich is something that I love to doand also pursued my premedical track. I think students should be more aware of this, because it is something that would be fun, add to your education and overall make it a more positive experience for your undergrad.

Grades matter. In fact, surveys of program directors put them at the top of the list of factors that evaluate the strength of an application. That having been said, you dont need four years of straight As to be a physician.

A good GPA is a 4.0, but not everybody can get there, said Sahil Mehta, MD, the founder of MedSchoolCoach. He noted that the Association of American Medical Colleges puts out these stats every single year, which I think gives a super helpful starting point for people to understand how competitive it is. The average applicant has around a 3.5.

The average of those admitted is around a 3.7, Dr. Mehta said. You really, as a premed, need to have even a 3.5 to even have a whiff of an opportunity. Really, I would say a good GPA, you're aiming more towards a 3.7, 3.8.

The MCAT is broken into four sections: biological and biochemical foundations of living systems; chemical and physical foundations of biological systems; psychological, social and biological foundations of behavior; and critical analysis and reasoning skills. A strong undergraduate course load in one of the traditional sciences will not prepare you for all of them. In fact, basic science knowledge, when paired with diligent MCAT prep, can probably be enough.

The MCAT tests basic science, Dr. Mehta said. These are sciences that you can do in one-year classes, right? The MCAT doesn't test biology 301. It tests biology 101. Even if you're a nonscience major, you're going to take biology 101 as a premed and you're going to have all the knowledge you need to do well on the MCAT.

You can also listen to the full episode onApple Podcasts,Google PlayorSpotifyand explore ourCareer Planning Resource.

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3 misconceptions undergrads have about applying to med school - American Medical Association

Construction to begin next year on medical school in downtown Wichita – KFDI

The city of Wichita has an agreement with a development group to convert four downtown buildings into a medical school, student housing, a culinary school and a hotel.

The city council has approved an agreement with Douglas Market Development, which owns the four buildings. The former State Office Building will be converted into the Kansas Health Science Center, and the former Sutton Place building will be remodeled to have 119 units for student housing.

The former Henrys building at 124 South Broadway will be converted into a commercial kitchen and culinary school, and the former Broadway Plaza Building at 109 South Broadway will be remodeled into a 119-room hotel that will be operated as a Marriott hotel.

Assistant city manager Scot Rigby said construction on the medical school is expected to begin by March, 2020, and the first class will begin in August of 2022. Work on the other buildings will also begin by March and they would be ready for occupancy in 2022. The entire project is a $90 million investment.

Jason Gregory with the Downtown Wichita organization said the project will bring life back to four vacant buildings and it will strengthen the Douglas Avenue and Williams Street corridors.

(above image is a rendition of the State Office Building as the medical school)

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Construction to begin next year on medical school in downtown Wichita - KFDI

Medical Education In The #MeToo Era: ‘No Option But To Stay Silent’? – WBUR

Harvard Medical School student Chloe Li typically dressed in scrubs or an efficient, professional outfit as she went about learning to care for patients in the intense, year-long clerkship program where I teach.

For her capstone presentation on graduation day, though, she wore a cream-colored wrap-around dress of luscious silk, tasteful jewelry and an up-do hairstyle. She had clearly put a lot of care into these preparations. She was a knock-out.

After the presentations, I gave Chloe a huge hug and congratulated her on her top-notch delivery of Cultural and Language Barriers in the Diagnosis and Treatment of Breast Cancer. And, as the mother of four daughters in their 20s, I spontaneously added: You look absolutely gorgeous tonight!

Then I noticed that two female associate program directors and a male clerkship director were standing nearby. Oy. A bit self-consciously, I inquired, I hope its OK for an attending physician to tell a medical student she looks gorgeous!

One of the associate program directors responded, Are you kidding? All weve been talking about is how beautiful she looks!

Chloe beamed and thanked us for noticing. The lone male just stood there with a pleasantly neutral expression on his face. Everyone had the same thought at the same time --it's true, I checked: "He has no option but to stay silent in this situation."

I could not help but tease him, an old friend who'd been my fellow resident a quarter century ago: What, come on, you dont think Chloe looks beautiful?

He paused, chuckled and protested, There is absolutely no right answer here!

Everyone laughed as we headed off to dinner. But I cant stop thinking about this 30-second intersection in time and space.

It felt liberating to acknowledge the usual eggshells underfoot, and then crush those eggshells, just like a wineglass at a wedding. Our male colleague (father of grown kids and co-founder of a center for mindfulness and compassion) chose to make a joke rather than join the circle of compliments. And he nailed that joke.

The punchline reflected the complex and problematic nature of todays social norms, and we could joke about them because we had known Chloe for a year, and each other for much longer, and had made ourselves vulnerable at many junctures as we struggled and learned together. Our laughter was permeated by a deep sense of trust and respect something our highly relationship-oriented program, the Cambridge Integrated Clerkship, aims to instill as students follow "their" patients under close faculty mentorship over time and across venues of care.

Far Fewer Words To Say They Care

At the same time, we were tacitly acknowledging that in this #MeToo day and age, male faculty members have access to far fewer words to tell female students that they care for them.

In October 2018, The New England Journal of Medicine published an article entitled Mens Fear of Mentoring in the #MeToo Era - Whats at Stake for Academic Medicine? This important piece made visible the reality that men in positions of power are often afraid to engage in mentoring relationships with women, with the unintended consequence of negatively impacting these womens careers.

Our graduation day interchange made me wonder whether there is something at stake beyond academic advancement. What is the cost to female students ability to learn, to their sense of connectedness to the profession, to their psychological well-being, if their faculty mentors are too cautious to fully engage in authentic relationships with them?

Ive heard of male attending physicianswho wont ask a female student a second question on rounds if she gets the first one wrong so as not to be perceived as bullying. A colleague from another institution once told me he didnt offer a female student a ride home in a terrible thunderstorm because he feared the perception of impropriety. I personally know a young pre-med woman whose male mentor will not meet with her unless her peer a young man who tends to dominate the conversation is also present. The mentor does, however, meet with him alone.

Is this what the antithesis of sexual harassment looks like in our world?

Dont get me wrong. This is by no means a call for men in power to be able to freely compliment womens appearance. And we must not stop rooting out abuses of power. The small minority of physicians who sexually harass their junior colleagues have no place in medicine, and important measures are being put in place to allow for confidential reporting and other forms of protection.

But I worry that when there is too much second-guessing, constant concern about accusations of harassment, too many prohibited words or topics that shift and morph constantly, a casualty of these prohibitions may be expressions of deep caring.

Dont be surprised if people dont cry with each other when a patient dies, or if they stop laughing together uncontrollably at silly jokes. Dont be surprised if medical education becomes less fun and meaningful.

My wise colleague Ed Hundert often quotes the old adage, You cant teach a stranger an important truth.I dont know what its like to work in Hollywood or the corporate world, but learning to be a physician requires intimate engagement with human stories and bodies, with suffering and ambiguity, and sometimes even with miracles.

The cultivation of such practical wisdom is the life-long pursuit of the good doctor, and it is hindered by unclear rules and intimidation.

A "Can't Stop Thinking About It" Moment

A few days after graduation, I shared a draft of this piece with Chloe and my colleagues, and asked about their take on the encounter. For each of them, it had been a significant "cant stop thinking about it" moment.

My male colleague thanked me for expressing things he could never say in public. My two female colleagues invited me to go out for a glass of wine to talk about the struggles and joys of a life in medicine. Chloe gave me permission to use her name and responded with a lovely email, drawing particular attention to the trusting, longitudinal relationships we intentionally cultivate in our model of medical education:

In the moment, I wanted so much to tell [the male clerkship director] that I had always known he regarded me with respect and care," she wrote. "The male physicians I look up to as mentors are probably continuously navigating such uncomfortable, unclear situations. I have never felt ill-treated in any way by any of these faculty members, but I feel that even if I had, I would have been able to tell them so, without fearing for my position or grade or safety. The ability to speak up with knowledge that you will be heard and without fear of retribution evens any field."

She added that if, however, she doesn't know a faculty member and has no context for a comment "whether its 'You look nice today!' or 'That was a dumb thing you said on rounds,' I am anxious about the intent behind the comment.

We have a ways to go. Even as a female faculty member, I worried (albeit for a quick second) that my own impulsive outpouring of pride and love on graduation day might have been perceived as inappropriate.

Chloes obvious gratitude made me toss the notion aside, but thats how it should be in medical education and in life, I think noticing our own moments of potential insensitivity, reflecting on them and adjusting if necessary. Apologizing if warranted.

In our institution, we provide forums for both students and faculty to confidentially share the day-to-day ethical challenges they encounter in medical culture: to problem-solve, role play and figure out how to do the right thing in this circumstance, with this individual. The #MeToo era raises similar questions:If what is an act of kindness in one circumstance bestowing a small gift or giving a hug, say can be considered a potentially career-ending interpersonal violation in another, how do we navigate these uncertain waters?

My male colleague was correct, there is no one right answer here. Maybe its not answers we need, but better questions to guide us. Maybe we can consider this one together: If faculty members' fear may be negatively impacting the development of our students, what would bravery look like?

Elizabeth Gaufberg, M.D., MPH, is an associate professor of medicine and psychiatry at Harvard Medical School/Cambridge Health Alliance, and a senior consultant with the Association of American Medical Colleges.

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Medical Education In The #MeToo Era: 'No Option But To Stay Silent'? - WBUR

Good Health Insurance Isn’t Enough To Fix Holes In The Social Safety Net : Shots – Health News – NPR

Democratic presidential candidates former Vice President Joe Biden (left), Sen. Elizabeth Warren, D-Mass., and South Bend, Ind., Mayor Pete Buttigieg (right) debate different ways to expand health coverage in America. John Minchillo/AP hide caption

Democratic presidential candidates former Vice President Joe Biden (left), Sen. Elizabeth Warren, D-Mass., and South Bend, Ind., Mayor Pete Buttigieg (right) debate different ways to expand health coverage in America.

The Democratic debate is less than a week away, and it's likely that health care will once again take center stage. Once again, the candidates will spar over the best way to achieve universal coverage. Once again, the progressives will talk up the benefits of "Medicare For All" while the moderates attack it for its high cost and lack of choice. Just like the last debate. And the one before.

But it's not the repetitiveness of the health care debate that bothers me. As a medical student, what bothers me is that the current health care debate is myopically focused on health insurance.

Although health insurance coverage is important, it's only part of the picture. If the goal of our health care system is to keep Americans healthy, insurance will only get us so far. Health is about much more than access to health care.

Asthma triggers when you're homeless

Take the case of a patient I helped treat this past summer, a young man in his early 20s who came into the emergency department experiencing severe shortness of breath. I could hear him wheezing before I even walked into the room.

He was sitting on the stretcher, breathing rapidly, and leaning forward with his hands on his knees the classic "tripod" position signifying respiratory distress. After the resident physician and I determined he was having an asthma attack, we controlled his symptoms with steroids and inhalers and monitored him until he improved.

As I was preparing to discharge the patient, I briefed him on some of the asthma triggers he should avoid. When I advised him to keep the windows closed to minimize his exposure to pollen, he told me that the shelter where he was staying didn't have air conditioning. It was 83 degrees outside that day.

Health insurance couldn't prevent his next asthma attack. He needed a better and more stable housing situation.

Food deserts and no ride to the doctor

The same was true for a second patient of mine who was admitted to the hospital with diabetic ketoacidosis, a life-threatening complication of diabetes resulting from poor blood sugar control. After he recovered, we discharged him home to a food desert, a neighborhood where grocery stores and fresh-food markets are scarce and where following a low-carbohydrate diet is next to impossible. Health insurance cannot solve the food insecurity in his community.

Nor could health insurance enable a third patient of mine who'd had vascular surgery to re-open a blocked artery in his leg to return for his follow-up visit. Had he done so, we would have caught his post-operative infection early. As it happened, however, he had no way of traveling the 15 miles from his home to our clinic, and his infection worsened to the point that we had to amputate two of his toes. Health insurance didn't address his transportation barriers.

Fortunately, all three patients were insured. Indeed, I'm grateful to attend medical school in Massachusetts, which has achieved near universal health insurance coverage. But sometimes insurance isn't enough. I constantly see cases like these in which acute health problems arise due to factors seemingly unrelated to medicine. Universal coverage, while a worthy goal, does not translate into universal health.

Who will fix holes in the social safety net?

A recent study that rated U.S. counties based on health outcomes found that access to medical care accounted for only 20 percent of a county's score. The other 80 percent was more readily attributable to social and economic factors like the ones affecting my patients, including housing instability, food insecurity, and access to transportation.

The health care dialogue in this political race has been dominated by the notion that we need to cover everyone, a principle I fully support. But even if we achieve that, it will only get us a fraction of the way to our goal of better health for all Americans. The German health care system is widely praised for its universal coverage, robust primary care, and low out-of-pocket costs for medical care. But it is nonetheless plagued with health disparities. In some cities, life expectancies of neighboring communities differ by up to 13 years.

To neglect these social factors in our public discourse on health care would be a mistake, not only because they are important to public health but also because policymakers are often better equipped to tackle social factors than they are medical ones. Evidence suggests that providing stable housing to homeless populations in urban areas, for instance, contributes to significantly reduced mortality.

Insurance coverage is a critical determinant of health. We should discuss it. But candidates for president should also discuss their plans to strengthen communities by addressing homelessness, food insecurity, and the other social factors that underpin America's health gap.

Thus far, these issues have received scant attention in the Democratic primary race and in the larger political dialogue about health care. We need to broaden the conversation from a narrow discussion of health insurance to a holistic conversation about health.

Suhas Gondi is a third-year medical student at Harvard Medical School. A version of this essay originally appeared in Undark, the online science magazine.

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Good Health Insurance Isn't Enough To Fix Holes In The Social Safety Net : Shots - Health News - NPR

Improving the Doctor to Patient Ratio in the African American Community – WVTF

Of the nearly 45,000 people who hold a Virginia medical license, only about 8% identify as African American. And that percentage is even smaller among younger physicians.

When 22-year-old Jared Bourke walked across the stage and became a graduate of Hampton University in 2018, he already had his eyes set on another graduation: VCU's School of Medicine class of 2022. His goal: Wearing a white coat.

You have to be fairly intelligent and use your brain, but you also have to be a people person and use your character to care for people. So, for me, thats the beauty of medicine and thats why this is the field for me, says Bourke.

The now 24-year-olds aware of all the barriers standing in the way of black medical students. There's the possibility of getting into immense debt, although most medical students expect some debt.

And if finances don't hamper aspiring black medical students, then there's the imposter syndrome that Bourke says many struggle with. "The first day of class was Monday and it was Saturday. I literally broke down in my car, on the way here (VCU). I'm not an emotional person, but I broke down in the car because I was like, yo, I'm really about to do what I've been trying to do since I started school. Like am I really smart enough to be here?"

One of the largest deterring barriers are the lack of African-American physicians serving as mentors.

In 2018, The Virginia Department of Health Professions (VDHP) conducted a "Physician Workforce Survey" where just over 33,000 physicians responded. Just under 1,700 respondents identified as black or African American in a state whose African American population exceeds 1.6 million, according to census data. That number is on the verge of decreasing even more as one-third of all physicians plan to retire before turning 65.

Researchers at VDHP say the overall number of practicing physicians in Virginia may be lower than 33,000 because some of those physicians have the license to practice in Virginia, but may live in another state or work on a military base.

"I grew up in Lawrenceville Virginia on the campus of St. Paul's College and my next door neighbor was a Dr. Clifton Nelson. He was a family doctor and he was the role model that I grew up with and wanted to be like him," Dr. Michele Whitehurst-Cook recounts. She's been practicing family medicine for 37 years.

She didn't tell me how much longer she'd practice medicine, but she did tell me about the watershed moment she had in high school program that provided training at VCU. "Once I spent six weeks here, seeing patients watching doctors do rounds helping nurses out, I realized that I wanted to really be involved in health care wanted to be a physician," says Whitehurst-Cook.

She attributes her medical school success to the African American physicians who nurtured her interest in Richmond and to her childhood neighbor, Dr. Nelson. But having a physician as your neighbor, especially in rural parts of Virginia, is a rarity. It's also a rarity for an African-American patient to have an African-American doctor.

In the Commonwealth, the black doctor to black patient ratio is approximately 1 doctor for every 1,000 patients. Meanwhile, the approximate ratio for white Virginians is 1 doctor for every 400 patients. And if you look at health disparity data it shows that if people are cared for by doctors who look like themselves they have a higher comfort level. They're willing to share more information. They're more trusting of their advice and health outcomes are actually better, says Whitehurst-Cook.

She says increasing the pool size of medical school cohorts and continual investment in pipeline programs will help close that ratio gap.

Policy experts like Lauren Powell, Director of the Office of Health Equity for the Virginia Department of Health, point to similar programs, but say that doesnt address structural issues. If we think about the criteria to get into medical school there historically has been a very heavy emphasis on the MCAT, MCAT scores and GPAs- how well you do doing the impact is really kind of a question of how much resource or how much money you may have to be able to really prepare.

Powell says its her job to make sure folks living in the poorest parts of Virginia have the same chance to achieve health and wellness as affluent Virginians. True health equity, as she puts it.

She believes focusing on population health and health equity, at the structural level, are the best ways to curve health outcomes for Virginians across the state. "Employment, food security, right. Reliable transportation, affordable and safe housing- All of these things combined together to really propel your health or to hinder your health," says Powell.

She admits its hard work in a burnout profession, across ethnicities, but says doctors and policy experts have to take the lead. Second year medical student Jared Bourke wants to be that doctor. A doctor who leads and empathizes with patients on a human and cultural level.

This report, provided byVirginia Public Radio, was made possible with support from theVirginia Education Association.

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Improving the Doctor to Patient Ratio in the African American Community - WVTF

The Match process is packed with stress. Ob-gyns aim to fix it. – American Medical Association

Between 2010 and 2019, the average number of applications submitted by medical students who want to match into ob-gyn residency programs has more than doubled, according to the Association of American Medical Colleges (AAMC).

An ambitious project proposed by residency programs within the specialty aims to simplify the Match process by reducing applications and creating a more equitable interview invitation system. Spearheaded by the Association of Professors of Gynecology and Obstetrics (APGO) and the Council on Resident Education in Obstetrics and Gynecology (CREOG), the program has received a $50,000 planning grant from the AMA Reimagining Residency Initiative.

The APGO programdubbed Right Resident, Right Program, Ready Day Oneis one of three programs to receive planning grants from the AMA. In total, the AMA Reimagining Residency Initiative awarded $15 million in grants to institutions who will aim to transform residency training to meet the workforce needs of Americas current and future health care system.

With the increasing number of applications submitted by each student, the process of securing a residency position has become more stressful. Final-year students spend a significant amount of time and money on the application process.

In the 201819 application cycle, students applying to ob-gyn programs submitted an average of 61.3 applications. Programs have seen a remarkable rise in the volume of applications. That number has grown from an average of 155 applications per program in 2010 to 438 in 2019, according to AAMC data.

That volume has created an environment in which program directors have less bandwidth to consider applicants holistically, defaulting to an evaluation process that overemphasizes test scores and increases stress in applicants.

Theres been a lot of writing in the literature recently about how this process needs to change, said Maya Hammoud, MD, president of APGO and a professor of obstetrics and gynecology at Michigan Medicine. With support from the AMA, we have started a five-year process by taking small steps to make sure we have all the stakeholders on board. At the same time, we are implementing small changes now to reduce anxiety among students. But this will not be an overnight process. It took many years to get to this point; it will take many years to get out of it.

To get the project off the ground in its early stages, the projects leaders are making sure to get buy-in from key stakeholders such as medical school deans, clerkship directors, residency program directors and representatives from the National Resident Matching Program.

A significant number of ob-gyn residency programs have already adopted suggested interventions that will standardize the residency application process. The three biggest changes are:

APGO has laid out longer-term goals for its efforts to reduce the stress involved with Match. These include development of additional application review metrics to encourage a holistic review of residency applications, an applicant compatibility index to help students with program selection, and an optional early match program within the specialty intended to reduce the number of applications needed for a successful Match.

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The Match process is packed with stress. Ob-gyns aim to fix it. - American Medical Association

Nanotechnology in Water Treatment Market Predicted to Accelerate the Growth by 2018 2026 – Industry Updates Daily

Overview

The research report provides valuable insights into demand drivers, geographical outlook, and competitive landscape of the Nanotechnology In Water Treatment Market for the 2018-2026 forecast period. Further, it throws light on restraints as well discusses opportunities at length that are likely to come to the fore over the forecast period. The analysis thus provided helps Market stakeholders with business planning and to gauge scope of expansion in the Nanotechnology In Water Treatment Market over the forecast period.

The report discusses the Market structure, including prevailing trends, size of the Market vis--vis revenue and volume, and finally forecasts values. Vital information, facts, and statistical figures provided for the Nanotechnology In Water Treatment Market are based on extensive primary and secondary research. Analysts also reached out to industry experts for their insightful inputs on the Nanotechnology In Water Treatment Market.

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Further, the report provides a comparative analysis of historical and current trends prevailing in the Nanotechnology In Water Treatment Market. This helps to estimate growth trends in the Nanotechnology In Water Treatment Market over the assessment period. Such comparative analysis is provided using an exhaustive collection of tables and graphical representations.

The report delves into the vendor landscape of the Nanotechnology In Water Treatment Market. The research report on the Nanotechnology In Water Treatment Market provides valuable insights on the competitive landscape of the Nanotechnology In Water Treatment Market. Besides this, the research report provides deep insights into growth strategies employed by key players, along with impact of these strategies on future business growth.

The SWOT analysis of key vendors along with a detailed profile of key vendors based on business overview, financial status, and product portfolio helps to gauge competitive dynamics in the Nanotechnology In Water Treatment Market. This analysis helps to gauge growth strategies to be employed by prominent vendors in the Nanotechnology In Water Treatment Market, and scope of collaborations and partnerships between these players.

The report includes an exhaustive list of top players in the Nanotechnology In Water Treatment Market:

Lanxess Aktiengesellschaft, ItN Nanovation AG, and Enel Spa.

Key Players

Further, Market share projections and changing competitive hierarchy in the Nanotechnology In Water Treatment Market until the end of the forecast period are vital offerings of this report.

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Nanotechnology in Water Treatment Market Predicted to Accelerate the Growth by 2018 2026 - Industry Updates Daily

Nanotechnology in Medical Devices Market Overview and Forecast Application from 2019-2025|3M – The Connect Report

Global Nanotechnology in Medical Devices market is a detailed research study that helps provides answers and related questions with respect to the emerging trends and rise moment in this particular industry. It helps select each of the easily seen barriers to rise, apart from identifying the trends within various application sector of the global market.

The study focuses on the driving factors, restraints and hurdles for the expansion of the market. The research worker offers Industry insights with reference to the approaching areas within the business and therefore the impact of technological innovations on the expansion of the market.

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3M, Dentsply International, Mitsui Chemicals, Stryker, AAP Implantate, Affymetrix, Perkinelmer, ST. Jude Medical, Smith & Nephew, Starkey Hearing Technologies

North America, China, Rest of Asia-Pacific, UK, Europe, Central & South America, Middle East & Africa

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Nanotechnology in Medical Devices Market Overview and Forecast Application from 2019-2025|3M - The Connect Report

Gene Editing Tool was Modified to Improve Therapies for HIV – Science Times

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The researchers from the City of Hope may have found a way to sharpen the cheapest, fastest, and most accurate gene-editing tool called the CRISPR-Cas9 so that it can successfully cut out undesirable genetic information. This cutting ability was improved so that one day, experts can fast-trackpotential therapiesfor sickle cell disease, HIV, and other immune conditions.

What is the CRISPR-Cas9 design

Tristan Scott, Ph.D., lead author of the study and a staff research scientist at City of Hope's Center for Gene Therapy, said that the CRISPR-Cas9 design might be the difference between trying to cut a rib eye steak with a butter knife versus cutting it with a steak knife. Other scientists have tried to improve CRISPR cutting through chemical modifications, but that is an expensive process, and it is like diamond-coating a blade. Scientists have designed a better pair of scissors that people can buy easily anywhere.

Thestudythat was done by Dr. Scott and his team was published in Scientific Reports, and it is the first time scientists have systematically gone through the guide RNA sequence to change it and to improve CRISPR-Cas9 technology. A patent application was filed at The Kevin Morris Lab at City of Hope, claiming this improved CRISPR-Cas9 design, which could result in a doubling of activity, but the exact amount was dependent on the target site.

Theeffects of this CRISPR-Cas9 designis downstream as it has more "clean" results in mouse model and cell experiments aimed at making new therapies because the target that was knocked out was more successfully removed. More results could quicken new therapies from the laboratory to patients' bedsides. The therapeutic product should have successful cuts, which could mean that an improved therapy is on the way, but further research is still needed. The exact ways and process of why this change to the CRISPR system improves gene editing still needs to be determined.

Experiments through nanotechnology

The researchers of the study experimented on cells by making certain changes to the tracrRNA or trans-activatingCRISPR RNAwhich they got from Streptococcuspyogenesbacteria, and it is a part of the components that are used to guide the genetic scissors, also known as Cas 9, to the right gene sequence. StreptococcuspyogenesCas9 is the most widely used genetic scissor. Dr. Scott and his team used an RNA protein system because it gives an increase of activity that disappears about 12 hours after being introduced into the cell, which means that there is a decreased chance of accidentally editing the human genelater after the fix has been made.

Scientists found that the modified tracrRNA improved the overall silencing of certain genes by increasing desirable mutations in the genetic material. In this study, the target was an essential component of HIV's lifecycle, the protein CCR5 on immune CD4+ T-cellsa current target in clinical trials seeking to re-create a person's immune system so they can be resistant to HIV. The modified tracrRNA had improved the overall cutting at this site and inactivation of CCR5, and hopefully, that will translate into better protection for the immune system.

The new tracrRNA design is better at improving the activity at the HBB gene and the BCL11A site. The HBB gene, which is responsible for producing beta-globin that is located inside red blood cells, and BCL11A, which may function as a leukemia disease gene, are targeted by the tracrRNA in order to make different therapies for HIV, which is known as a blood disease that does not have any known cure yet.

Dr. Scott stated that if the line of research remains consistent, and they can dependably sharpen the genetic scissor, the result could eventually be new or improved genetic therapies. He also said that his team is at the beginning of a long scientific process.

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Gene Editing Tool was Modified to Improve Therapies for HIV - Science Times

C-Bond NanoShield Takes a Top Award at the 2019 Fleet Europe Summit in Portugal – GlobeNewswire

HOUSTON, Nov. 12, 2019 (GLOBE NEWSWIRE) -- C-Bond Systems (the Company or C-Bond) (OTC: CBNT), a nanotechnology company that improves and strengthens glass, announced today that its C-Bond NanoShield windshield strengthening solution received a top award at the 2019 Fleet Europe Summit in Estoril, Portugal. C-Bond NanoShield finished among the top three of nine finalists for the 2019 Fleet Europe Innovation Award.

The Fleet Europe Innovation Award 2019 rewards innovative solutions, products or services from the international fleet supplier industry, which includes manufacturers, leasing and rental companies, fuel and insurance specialists or other vehicle fleet suppliers.

C-Bond NanoShield protects and strengthens windshields by permeating the glass surface and repairing the microscopic flaws and defects randomly distributed all over the glass surface that ultimately initiate chipping and cracking. The product is sprayed directly onto a windshield and then wiped off using a squeegee. The strengthening process begins immediately upon application and continues while the material cures in the following days.

The value proposition of C-Bond NanoShield for fleet management is simple: C-Bond NanoShield reduces windshield chipping and cracking, therefore reducing the need for windshield repair and replacement, stated Scott R. Silverman, Chairman and CEO of C-Bond. That can represent asignificant cost and time savings for fleet management companies, not to mention increased safety for drivers.

The Fleet Europe Summit is the number one international conference in Europe for all fleet and mobility leaders. This two-day event combines information, education, networking and knowledge sharing. It gathers yearly over 1,000 fleet and mobility decisions makers and influencers.

About C-BondC-Bond Systems, Inc., headquartered in Houston, Texas, is an advanced nanotechnology company and sole owner, developer and manufacturer of the C-Bond technology. C-Bond is a patent-protected nanotechnology that is scientifically tested and commercially proven to significantly increase the strength, safety and performance levels of glass and window film products. For more information visit us at http://www.cbondsystems.com, on Facebook, or Twitter.

Statements in this press release about our future expectations constitute "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934, and as that term is defined in the Private Litigation Reform Act of 1995. Such forward-looking statements involve risks and uncertainties and are subject to change at any time, and our actual results could differ materially from expected results. These risks and uncertainties include, without limitation, C-Bonds ability to raise capital; the Companys ability to successfully commercialize its products; as well as other risks. Additional information about these and other factors may be described in the Companys filings with the Securities and Exchange Commission (SEC) including its Form 10-K filed on April 1, 2019, its Forms 10-Q filed on August 12, 2019, May 10, 2019, and November 14, 2018, and in future filings with the SEC. The Company undertakes no obligation to update or release any revisions to these forward-looking statements to reflect events or circumstances after the date of this statement or to reflect the occurrence of unanticipated events, except as required by law.

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C-Bond NanoShield Takes a Top Award at the 2019 Fleet Europe Summit in Portugal - GlobeNewswire

Global Nanotechnology in Medical Devices Market 2019: Growth, Size, Share, Analysis and Forecast to 2025 – Daily Industry News Journal

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Global Nanotechnology in Medical Devices Market 2019: Growth, Size, Share, Analysis and Forecast to 2025 - Daily Industry News Journal