2019 Top Doctors in the Philadelphia and Main Line Areas – Mainline Today

Who are the best physicians in the region? To find out, we went to the doctors themselves. Via online ballot, they chose the practitioners they most trust in a variety of specialties.

Compiled by Melissa Jacobs

Top doctors Seema Bonney, Tarun Mathur and Jennifer Simmons. Photo By Tessa Marie Images.

#1 Sarah FalgowskiCrozer-Keystone Recovery CenterChester(610) 497-7200

James BermanPenn Addiction MedicineHaverford(610) 642-1904

Arlin SilbermanCrozer-Keystone Psychiatry CollaborativesUpland(610) 874-5257

Jaakko Lappalainen, Sherry NykielCrozer-Keystone Recovery CenterChester(610) 497-7200

Elena Del BustoPsychiatric Associates of PennsylvaniaHaverford(215) 565-1005

Karen NewmanSpringfield PsychologicalHavertown(610) 544-2110

Aviva FoherThalia Medical CenterArdmore(610) 455-4254

Frederick Stoddard IIHaverford(215) 565-1005

Related Article:The Pulse: Must-Attend November and December Wellness Events

#1 Corinna BowserNarberth Allergy and AsthmaHavertown, Narberth484-270-8584

Mahmoud EffatChester County AllergyExton(610) 363-0907

George L. MartinAllergy & Asthma ProfessionalsWynnewood(610) 649-9300

Sandhya Desai, Annie KhuntiaAllergy & Asthma SpecialistsMultiple Locations(800) 86-COUGH

Sandra Gawchik, Anthony RooklinAsthma & Allergy AssociatesGlen Mills, Chester, West Chester(484) 816-4462,

Shailen ShahAsthma & Allergy Consultants of NJ-PACape May Court House, Collegeville, Marlton(610) 409-9440

Manav SegalChestnut Hill Allergy & Asthma AssociatesPhiladelphia, Wyndmoor(215) 247-2292

Thomas Klein, Michael Prematta, Tracy PremattaKlein Allergy and AsthmaMultiple Locations(610) 789-1313,

Michele Columbo, Albert RohrRohr and Columbo Asthma, Allergy and ImmunologyBryn Mawr, Paoli(610) 527-2000

Alyson Simpson LazovitzSimpson Allergy and AsthmaConshohocken, Lansdale, Ambler(267) 416-0212

#1 Michael CabralUnited Anesthesia ServicesMultiple Locations(610) 525-4966

Olesh Babiak, Adam Hauser, Lawrence LevitAssociates in AnesthesiaMultiple Locations(610) 447-6579

Lisa Held, Corinne WongBryn Mawr Hospital AnesthesiologyBryn Mawr(484) 337-4947

Ernest RiccoRiddle Hospital AnesthesiologyMedia(484) 227-3229

Richard Banner, John NguyenUnited Anesthesia ServicesMultiple Locations(610) 525-4966

Michelle Beam, Glenn Ereso, Larry Kim, Raymund SantosWest Chester Anesthesia AssociatesWest Chester(610) 789-7366

#1 Michael WalkerMLHC Thoracic SurgeryBryn Mawr(610) 527-1600

Karl GrunewaldHAN Cardiothoracic Surgeons of Delaware CountyUpland, Glen Mills(610) 619-8477

Deon VigilanceMercy Thoracic Surgery at Mercy Fitzgerald HospitalDarby, Philadelphia(484) 494-6920

Patrick RossMLHC Thoracic SurgeryBryn Mawr(610) 527-1600

Robert WengerPenn Cardiovascular Surgery Chester CountyWest Chester(800) 789-PENN

Doraid JarrarPenn Medicine Valley ForgeBerwyn(800) 789-PENN

Ravishankar RamanTemple Cardiac Care at BrandywineCoatesville(610) 383-8434

#1 (tie) Sheetal ChandhokBryn Mawr Medical Specialists AssociationBryn Mawr, Newtown Square(610) 527-1165

#1 (tie) Kurt SchillingerChester County CardiologyWest Chester(800) 789-7366

Michael SabadishBrandywine Valley CardiologyThorndale(610) 384-2211

Glenn HarperBryn Mawr Medical Specialists AssociationBryn Mawr, Newtown Square(610) 527-1165

Matthew Goldstein, Danesh Modi, Colin MovsowitzCardiology Consultants of PhiladelphiaMultiple Locations(215) CCP-DOCS

Douglas Esberg, Colleen Hanley, Maribel Hernandez, Steve Rothman, Kar-Lai WongLankenau Heart GroupMultiple Locations(866) 225-5654

Matthew HillisMarple Medical AssociatesBroomall(610) 353-6400

Hope HelfeldWest Chester CardiologyWest Chester, West Grove(610) 692-4382

#1 Tarun MathurBryn Mawr Medical Specialists AssociationBryn Mawr(610) 525-1202

Arthur Hodess, Pamela Mauer, Alexander ShpilmanBrandywine Valley CardiologyThorndale(610) 384-2211

Jason Bradley, Sean Curran, John Fisher, Laura Immordino, Howard Kramer, Lawrence MendelsonBryn Mawr Medical Specialists AssociationBryn Mawr, Newtown Square, Wynnewood(610) 525-1202

Nirav Mehta, Leo Podolsky, Richard Schott, Matthew Sewell, Kevin ShinalCardiology Consultants of PhiladelphiaMultiple Locations(215) CCP-DOCS

Timothy Boyek, Greg Neithardt, Jeffrey Wahl, Clay WarnickChester County CardiologyWest Chester(800) 789-7366

Kimberly CampbellDelaware County Memorial HospitalDrexel Hill(610) 259-0240

Robert Belasco, Paul Casey, Harindar SharmaEinstein Healthcare NetworkCollegeville, East Norriton(610) 831-0300,

James Burke, George Chamoun, Steven Domsky, Christopher Droogan, Katie Hawthorne, William Kornberg, Richard McCurdy Sr.Lankenau Heart GroupMultiple Locations(866) 225-5654

Mark Edelstein, Julian Gladstone, Richard Lichtenberg, Mark Lisberger, Michael TobinMarple Medical AssociatesBroomall(610) 353-6400

Richard HunnMercy CardiologySpringfield, Darby(484) 479-2600

Kelly Anne SprattPenn Medicine Valley ForgeBerwyn, Philadelphia(800) 789-7366

Mian JanWest Chester CardiologyWest Chester, West Grove(610) 692-4382

#1 Eric GnallLankenau Heart GroupMultiple Locations(866) 225-5654

Antonio Chamoun, Chirdeep PatelBrandywine Valley CardiologyThorndale(610) 384-2211

Sarang MangalmurtiBryn Mawr Medical Specialists AssociationBryn Mawr(610) 527-1165

Aaron Giltner, Richard TucciCardiology Consultants of PhiladelphiaPaoli(610) 647-4260

Joseph LewisChester County CardiologyWest Chester(800) 789-7366

Amid Khan, Frank McGeehin, Timothy ShapiroLankenau Heart GroupMultiple Locations(866) 225-5654

Antonis PratsosMarple Medical AssociatesBroomall(610) 353-6400

#1 Francis SutterLankenau Heart GroupMultiple Locations(866) 225-5654

Charles GellerHAN Cardiothoracic Surgeons of Delaware CountyUpland(610) 619-8477

Scott Goldman, Matthew Paulus Thomas, Konstadinos Plestis, Roberto RodriguezLankenau Heart GroupMultiple Locations(866) 225-5654

Steven WeissChester County CardiologyWest Chester(800) 789-7366

Related Article:This King of Prussia Dermatologist-Turned-Designer is Leading the Fashion Wellness Movement

#1 Danielle DeHoratiusDermatology Associatesof Bryn Mawr Medical SpecialistsBryn Mawr, Wynnewood(610) 642-1090

Jamie AltmanAesthetic Dermatology AssociatesMedia, Paoli(610) 566-7300

Kari Boucher, Lisa CarrollBrinton Lake DermatologyGlen Mills(484) 785-3376

Christine StankoBryn Mawr DermatologyCollegeville, Villanova(610) 525-7800

Kara Capriotti, Victoria Cirillo-HylanBryn Mawr Skin & Cancer InstituteWest Chester, Newtown Square, Rosemont(610) 525-5028

Michael Gober, Daniel Roling, Rochelle WeissDermatology Associates of Bryn Mawr Medical SpecialistsBryn Mawr, Wynnewood(610) 642-1090

Elizabeth BenstockDermatology Associates of Delaware ValleyNewtown Square(610) 325-5553

Christine EganDermatology Ltd.Glen Mills, Media(610) 566-7111

Clifford PerlisKeystone Dermatology PartnersKing of Prussia(215) 390-1449

Erum IlyasMontgomery DermatologyKing of Prussia(610) 265-1166

Michele ZiskindPaoli Dermatology & Plastic Surgery GroupPaoli(610) 296-5801

Alexis CurreriPennsylvania Dermatology PartnersMultiple Locations(610) 337-3195

Adrienne RencicRencic DermatologyGlen Mills(610) 558-1446,

Stacey Englander TurnerTurner DermatologyBryn Mawr(610) 525-3800

#1 Stuart BrilliantPaoli HospitalPaoli(484) 565-1000

Kenneth Doroski, Scott McCurlyBrandywine HospitalCoatesville(610) 383-8000

Joshua Baron, Blair Hontz, William SteriousBryn Mawr HospitalBryn Mawr(484) 337-3000

Davis Clark, Diane Kane, Christopher WareChester County HospitalWest Chester(610) 431-5000

Ana Davitt, Christine Giesa, Ralph RivielloCrozer-Chester Medical CenterUpland(610) 447-2188

Steve Costalas, Basil HarrisLankenau HospitalWynnewood(484) 476-2000

Joseph BushraNarberth Ambulance, Lankenau Medical CenterWynnewood484-476-2000

Steven Gamburg, Duane Godshall, Andrea Horvath, David NathanPaoli HospitalPaoli(484) 565-1000

Steven MoonblattRiddle HospitalMedia(484) 227-9400

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2019 Top Doctors in the Philadelphia and Main Line Areas - Mainline Today

Nutrigenomics Market: Share, Size, Opportunities, Growth, And Industry Analysis And Forecast 2019-2025 – .Automotiveindustrytrend

The market research report is a perfect tool for digging deep into critical aspects of the Global Nutrigenomics Market and closely understanding factors that influence its growth. Our research analysts are experienced enough to provide you the right information about the global Nutrigenomics market to help your business propel forward in the coming years. What makes us different from other market researchers is our high level of analysis that helps you to identify key opportunities available in the global Nutrigenomics market. The report provides every bit of information about the global Nutrigenomics market related to major market segments, vendor landscape, geographical growth, and other significant factors.

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Get detailed segmentation of the global Nutrigenomics market according to type of product and application. The report also covers important technologies used and services provided by leading companies of the global Nutrigenomics market. It provides details about latest industry trends observed in different market segments. By providing market forecasts of each segment in terms of volume and revenue, the report enables market players to focus on high-growth areas of the global Nutrigenomics market.

The authors of the report profile leading companies of the global Air Purifiers market, such as

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Regions Covered in the Global Nutrigenomics Market:

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Key Picks from TOC

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Market Share by Region: In this section is included a study on the production of Nutrigenomics in different regions and countries. Each geographical market studied in the report is analyzed on the basis of gross margin, price, revenue, and production.

Company Profiles: This section is entirely dedicated for company profiling where leading market players are evaluated on the basis of different factors.

Global Nutrigenomics Market Forecast

Research Methodology

We follow an ideal mix of primary and secondary research methodologies. One of the most extensive stages in our research process is information procurement. Under information analysis, we map and analyze all the information procured by our analysts. This step also involves analyzing data discrepancies found across different data sources. In order to deduce viable conclusions, we place data points at appropriate market spaces. Validation is the final and a very important step before the publishing of the report. We employ an intricately designed process for validation and re-validation to finalize data points for their use in final calculations.

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About Us:QYR Consulting established as a research firm in 2007 and have since grown into a trusted brand amongst many industries. Over the years, we have consistently worked toward delivering high-quality customized solutions for wide range of clients ranging from ICT to healthcare industries. With over 50,000 satisfied clients, spread over 80 countries, we have sincerely strived to deliver the best analytics through exhaustive research methodologies.

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Nutrigenomics Market: Share, Size, Opportunities, Growth, And Industry Analysis And Forecast 2019-2025 - .Automotiveindustrytrend

2020 Will Be The Year of Self-Care With These Top Health and Wellness Trends – Essence

With a new year on the horizon, its no surprise that wellness enthusiasts are already looking ahead to forecast how theyll take their self-care to the next level. Just about every week, it seems like a new Soul Cycle or Equinox has popped up and emerging wellness brands such as FaceHaus, Shape House and Nap Bar are continuing to grow in appeal and popularity.

According to the Global Wellness Institute, the global wellness market is now valued at $4.2 trillion, up 12.8% from $3.7 trillion in 2015 and its only expected to continue growing over the next few years as we continue to recognize the importance of valuing ourselves first. As a result, and in an attempt to capitalize on consumer demand, just about every brandfrom weight loss oriented companies such as WW and Jenny Craig to consumer brands such as Nestl and GM is repositioning itself as a wellness company. Its a trend known as the pivot to wellness.

Our friends at MINDBODY recently conducted a 2020 wellness index study, and heres where they think youll be spending all your coins next year to help you get zen.

Experiential Wellness

People love to experience wellness with the most common being spa retreats, fitness pop-ups and wellness festivals. Forty-two percent of those polled valued experiences over material possession. That means in 2020, youll see your favorite brands capitalizing off the intersection of things you love to do trap meets yoga, fitness pop-ups that intersect your favorite apparel companies, and we cant forget wellness-focused vacations such as Cayman Rejuvenate and the Integrative Health Retreat at Carlisle Bay.

More Sleep

Sleep: were all craving it, but likely not getting enough of it. According to the National Sleep Foundation, forty-five perfect of Americans arent getting the sleep they deserve, but that will likely change in the new year. As people want to make this a growing priority, MINDBODYs research showed that 57 percent of people consider sleep to be a luxury (and not a necessity), with 28 percent using sleep apps, to help with this. Expect more downloads of Sleep Cycle and Relax Melodies to help put you down each night. Other ways you can try to prioritize your sleep in 2020 include natural supplements, non-toxic mattresses and bedding such as Casper and Purple, or even popping in midday at a nap pod, such as Houstons Nap Bar.

Emotional Wellness

Our emotional well being is just as, if not more important than physical. Seventy-five percent of those surveyed in MINDBODYs 2020 Wellness Index study agree that personal wellness is a never-ending quest, and this will be seen in the new year by focusing on sustainable and realistic eating habits as well as making more time for your mental health whether it be with therapy, meditation, journaling and expressing gratitude more often. This will be seen by individuals making both small and large actions to preserve their sanity which as Black women, we need to spend more time doing.

Complementary and Alternative Medicine

While Dr. Sebi had been promoting this for decades, mainstream America just now seems to be catching on. Complementary and alternative medicine (CAM) continues to gain in popularity, so much so that 68% of those surveyed in the MINDBODY Wellness Index study agree that alternative medicine is a good complement to modern medicine. In addition to the most popular forms of this, like meditation, guided visualization, and breath work, getting acupuncture, acupressure, and even ear seeding are a few rising practices that will become a lot more accessible in the next year. So, it is no surprise that in 2020 many consumers will look to alternative medicine when it comes to healing and recovery of both the mind and body.

Excerpt from:
2020 Will Be The Year of Self-Care With These Top Health and Wellness Trends - Essence

Montefiore celebrates its care during National Hospice Month – Cleveland Jewish News

It was after Ed Blumenthals sudden drop in motor function that his wife, Fay, knew she would have to make the decision she had been hesitant to make.

The 83-year-old Beachwood resident had dedicated the past 10 years tending to her 84-year-old husband who had been diagnosed with progressive dementia, but she knew deep down that what she referred to as Eds bad day in December 2018 where he suddenly went flat foot and injured himself and an aide was a sign that Ed needed more personalized and intense care his current hospice doctor couldnt provide just through home visits.

And so, instead of Ed Blumenthal being transported to the hospital following his fall, he went to the place where he could receive specific medical care and therapy for the remaining months of his life until his death in July 2019 Montefiores Maltz Hospice House in Beachwood, where he had already been receiving Montefiores Vinney Hospice and Palliative Care through home visits. November is National Hospice and Palliative Care Month.

Ed had been getting medical service at home through Cleveland Clinic, and the nurses and doctors came out from Cleveland Clinic and said, You know, hes hospice level. You should consider getting hospice services, Fay Blumenthal said. I had the choice of using Cleveland Clinic or a number of facilities, and after doing some interviews, I made the choice to use Montefiore. It proved to be a good choice.

Fay and Ed Blumenthal in 2015.

Montefiore, an assisted living, hospice, long term and post-hospital home care, health care services and memory care facility with locations in Beachwood and Bainbridge Township, offers a hospice program that prioritizes individualized treatment and care above all else with its Vinney Hospice and Palliative Care program. Vinney Hospice patients are assigned a team of a hospice physician, nurse, nursing assistants, medically oriented social worker and chaplain to meet every need they might have.

The six-bed Maltz Hospice House is for hospice patients in need of intense, symptom-calming care to eventually return home or patients close to end of life. While the house is made comfortable for patients with suite-style rooms with full bathrooms and individual patios, families who visit or stay over have access to pullout couches, a kitchen, two living rooms, a kids playroom, a meditation room, outdoor gardens and other amenities.

Dr. Barbara Messinger-Rapport, medical director of Vinney Hospice and Palliative Care of Montefiore, is responsible for all medical oversight of the hospice program and the Maltz Hospice House. She was named medical director in early 2019, but has worked with Vinney Hospice since 2010 in various positions. Shes held a number of geriatric medicine positions with Cleveland Clinic, including director of geriatric medicine, where she completed her geriatric medicine fellowship and geriatric medicine and hospice and palliative care medicine certification, and the VA Northeast Ohio Healthcare System.

Dr. Barbara Messinger-Rapport

What drew me to Vinney Hospice was the opportunity to help patients and their families make choices at the end of life that would improve the quality of their care and help facilitate the caregivers ability to take care of their loved ones and themselves, because many caregivers of those at end of life are elderly themselves, Messinger-Rapport said.

One of the many things that makes Vinney Hospice special in Messinger-Rapports eyes is that she only sees about 70 patients, giving her the opportunity to personally get to know her patients and their families on a much more intimate level.

For that period of time, weeks or months, Im the physician that tends to know the patients and their needs the best because even if Im not the primary care physician and Im just a consultant, Im often dropping by, she said. If I cant do that, Im checking with the hospice team who go into the home to take care of them. I form very close relationships with families because toward the end when patients are no longer able to express themselves, its the families that have to advocate and make sure that patients wishes are honored. I try to make myself available to them all the time to make sure that they know that theyre able to request the things for their loved ones that would help their quality of life.

Messinger-Rapport, a resident of Highland Heights and who attends Temple Emanu El in Orange, visits patients receiving her care even if they live at home in the Beachwood area or other parts of Northeast Ohio often on her bicycle, giving her the nickname bicycle doctor by her patients and Geagua County where The Weils, another campus of Montefiore, is located.

Cindy Smith, a Vinney Hospice nurse for nine years, makes a bed in the Maltz Hospice House.

Vinney Hospice patients also have access to a list of integrative therapies, including Reiki treatments, massage, music and art therapies. The therapies can help patients cope with their illnesses, but they can also provide an opportunity for patients to connect with their family.

Many patients toward the end of life are aware that their time is short and they want to leave a legacy behind, Messinger-Rapport said. We have one patient who is working with her art therapist to write holiday cards for her grandchildren. She might not live to Chanukah, but the grandchildren will have cards from her that she will dictate and the therapist will help her draw pictures and help write a message for her.

A part of the clinical team of nurses and social workers assigned to patients, they also have a chaplain who helps address any spiritual concerns they or their family might have.

Just like the nurse writes an assessment about the heart rate and the blood pressure and weight, we have to assess when a person comes to us, like how much fear and anxiety they have, how much purpose they have, how faithful they are to whats happening, do they believe in God, said Rabbi Akiva Feinstein, Vinney Hospice chaplain and director of spiritual care.

We try to assess and evaluate, and we share the results with the other people on the hospice team. And in that kind of sharing, we help each other out with the process.

Even if a patient isnt particularly religious, Feinstein works with patients with whatever concerns they might have to make sure theyre able to pass on unafraid and content with the lives they lived.

Rabbi Akiva Feinstein

Its basically a way of serving the deeper human needs that sometimes can be hard to define, he said. The people that we serve, theyre thinking about many things. Theyre thinking about leaving this world, theyre thinking about closure or things that they didnt do right. Theyre thinking about what the next world is going to be like. Spiritual care is helping them and guiding them with those questions without making them come to a religious approach. Its just utilizing whats in them, utilizing their thinking and the feelings, heart and soul of a person.

Feinstein, a resident of Cleveland Heights, greatly helped Fay Blumenthal during Ed Blumenthals time in the Maltz Hospice House, as he was always there for the both of them whether it was for Ed Blumenthals love of attending Shabbat services in Montefiore or making sure Fay Blumenthal was OK throughout the process.

Rabbi Feinstein, he went out of his way, Fay Blumenthal said. On the Friday before Ed died, we would have gone to the service, but we didnt go cause he was in bad shape. Rabbi Feinstein brought Eds cousin to see him, and that was so thoughtful. Then Ed died on Sunday, and we were sitting there after they prepared his body. Rabbi Feinstein sat with us for over an hour and he read psalms. It was just beautiful. You dont expect someone to do that, to have someone just sit with you for over an hour.

While Fay Blumenthal had to go through the painful process of losing her husband of 61 years, she was thankful for Montefiore, the staff and the care Ed Blumenthal received to allow him to pass painlessly and calmly.

It had become too hard to care for him at home, and I needed the help, Fay Blumenthal said. Im glad I made the decision when I did. I think it turned out to be a good choice.

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Montefiore celebrates its care during National Hospice Month - Cleveland Jewish News

Synthetic bear bile could improve effectiveness of human heart transplants – The New Economy

While synthetic bear bile may well do little to reduce demand for the real thing in parts of Asia, it is currently being explored for some potentially phenomenal developments in western medicine

For thousands of years, practitioners of traditional Chinese medicine have used bear bile as a natural treatment for a number of ailments. A digestive fluid thats produced by the liver and then stored in the gallbladder, its used principally for reducing fever and inflammation, detoxifying the liver [and] resolving gallstones, explained Dave Garshelis, a wildlife research scientist for the Minnesota Department of Natural Resources and one of the worlds leading bear experts. He also noted that the substance has anti-inflammatory properties.

Unsurprisingly, there is a great deal of controversy surrounding the collection of bear bile, which occurs via two methods. Though it is illegal in many parts of the world, the first method involves hunting wild bears. Once caught, they are drained of their bile and often used for other body parts too. The other method involves bear farming: in this case, bears are kept in cages and hooked up to drainage tubes and catheters for months at a time. Many are kept in captivity for their entire lives.

The farming of bile was actually designed in North Korea, but it moved into China in the 1980s, Garshelis told The New Economy. From the standpoint of a communist government, it was designed as a way to satisfy the medical demand for bear bile. So they felt that they had a country of people of which a large proportion use traditional medicine, and there wasnt actually enough bear bile to go around They couldnt supply it, and so they were trying to find a way to develop a larger supply, and thats how this farming came to be.

While synthetic bear bile may well do little to reduce demand for the real thing, it is currently being explored for some potentially phenomenal developments in western medicine

Heart transplantsThat bear bile has some incredible properties is hard to deny. In fact, its something that Paul Iaizzo, a professor in the departments of surgery, integrative biology and physiology at the University of Minnesota, has been examining for more than 20 years.

We have been studying hibernating black bears and whats amazing about these bears [is that] for four to six months they can elicit extremely low heart rates and they remain mildly hypothermic their body temperature goes down to only 35 or 36 degrees centigrade [but] they lose very [few] functional abilities, Iaizzo said. The heart rates can be as low as five or 10 beats per minute, and yet at any time they can be aroused and elicit a flight or fight response to defend themselves against predators, which is really amazing. Further, they lose very little to no skeletal muscle or cardiac masses or functions; that is again during this period of anywhere from four to six months where theyre in a state of total starvation and taking little or no fluids.

Taking this understanding and applying it to modern medicine, Iaizzo and his team are currently using synthetic bear bile a high dose of fatty acids and delta opioid agonists, which are upregulated in hibernating bears in a bid to improve the success rates of surgical outcomes and organ transplants. Essentially, in the same way that the unique blend of chemicals helps sustain a bears organs from going into atrophy during the hibernation period, it can be used to protect human organs during the transplant process.

Routinely, our laboratory will isolate large mammalian hearts for reanimation, Iaizzo told The New Economy. Well often precondition the organs, and we have been able to show enhanced viabilities if we do that. If we use a preconditioning of delta opioids, fatty acids, bear bile acids or some combination of these, we have elicited improved functions immediately after reanimation and for extended periods.

This could be a game-changer for organ transplants. At present, there is only a narrow window of around six hours in which a heart can be removed from a donor and transplanted into a recipient. Synthetic bear bile, however, could theoretically increase this by up to 24 hours, meaning that a heart could be transported to pretty much anywhere on the planet. By increasing the number of organs available, thousands of people waiting for heart transplants could be saved.

It could also help with the procedure itself. Transplanting a heart involves removing it from the donor, packing and icing it, and oftentimes transporting it to another location. During this time,ischaemia, where the organ is prevented from getting enough oxygen, can occur. But Iaizzo believes that preconditioning the heart with these upregulated hibernation factors from bears could limit ischaemic damage. This is particularly crucial for organ recipients who have other medical issues, aside from cardiac problems.

If I can minimise the consequences of ischaemic damage and put that heart or any organ in that recipient, it should function better immediately, it might decrease complications and the ICU [intensive care unit] stays, and [lead] to long-term better outcomes, Iaizzo said. So this is what were pretty interested in.

Muscle atrophyTheres potential for other areas too, particularly in terms of muscle weakness and patients who have been immobilised during intensive care. As Iaizzo explained, despite various methods to help alleviate this, patients can fall into hypercatabolic states, in which they can lose up to 50 percent of their muscle mass within just a few weeks. And when that happens, very typically theyll end up on the ventilator, and if that happens the outcomes are usually not good, he added.

As such, Iaizzo is examining how bears manage to maintain high levels of muscle function and lose minimal skeletal and cardiac muscle masses while immobilised during hibernation, and how this can be applied to such patients. His research starts with looking at the cascade of hormones that is released during hibernation also known as hibernation induction triggers.

Weve started out collaborating with Peter Oeltgen at the University of Kentucky He had been looking at the plasma from hibernators and looking at these molecules, and showed that they had specific properties that could be protective of organs and muscle against ischaemia, Iaizzo said. And so we then started looking more into that and [bears] actually have increased levels of these hormones during hibernation, as well as increases in their circulating bile acids and fatty acids. So then were trying to tease apart which is most critical is it the circulating hormones, bile acids or the high levels of fatty acids or a required combination? And so, if we could figure that out, there might [be] greater applications to human medicine relative to patients in the ICU or organ transplantation, or just cardiac surgery in general.

Natural versus syntheticIaizzo and his team are doing some fascinating work with synthetic bear bile using lessons learned from nature to improve the survival rates of those awaiting heart transplants is nothing short of extraordinary. It also demonstrates that there is viability to using synthetic bear bile as opposed to the real thing, which, considering the methods employed and the sources themselves, is inarguably cruel.

But whether this lesson will translate to those still poaching and farming bears, or those selling and using bile, is unlikely. Traditional Chinese medicine involves a deep-seated belief system for the millions of people who use such treatments. They really believe in a balance in taking their medicine and that the bear bile itself, with all of its components has a more balanced effect on your body than just what is considered to be the active ingredient a compound called ursodeoxycholic acid, which can be created in a lab, Garshelis explained.

The notion of using natural remedies is fundamental in traditional Chinese medicine, and this is where synthetic alternatives fall short. There is the belief that the bile that comes from a bear, which is composed of many different compounds that have yet to be synthesised, is just inherently better than artificial bile, where these substances are absent, Garshelis added.

While synthetic bear bile may well do little to reduce demand for the real thing, it is currently being explored for some potentially phenomenal developments in western medicine. It also highlights the possibilities available to scientists when they study the countless facets of the natural world. Maybe we should go back to these more natural remedies and look back to the past, Iaizzo said. For example, many have been used in eastern medicine for thousands of years. Indeed, imagine what treasures of information there are out there to be discovered or rediscovered, as the case may be.

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Synthetic bear bile could improve effectiveness of human heart transplants - The New Economy

Study Shows Evolution Turns Genes Back On to Regain Function – Stony Brook News

STONY BROOK, NY, November 25, 2019 Genes often mutate and lose their natural or synthetic function over long-term evolution, which could be good if that stops drug resistance of infectious microbes or cancer. A new study by Stony Brook University researchers, published online in PNAS, shows that evolution can exploit positive feedback (PF) within cells to restore gene function. Such repair by evolution may provide a basis for regaining lost gene function, which has implications in medicine and other scientific endeavors.

Based on the idea and experiments of an undergraduate Biomedical Engineering student, Mirna Kheir, and led by Gbor Balzsi, PhD, the Henry Laufer Associate Professor in Stony Brook Universitys Laufer Center for Physical and Quantitative Biology, and Department of Biomedical Engineering, the study included using synthetic PF in yeast cells by way of a chromosomally integrated gene circuit to test the process of regaining lost gene functions.

We showed through these experiments and computational models that many drugs can activate mutant resistance genes through this process, explains Balzsi. Essentially we exposed mutant, drug-sensitive cell populations to conditions where regaining resistance would be beneficial, and we found adaptation scenarios with or without repairing lost gene circuit function.

The results also suggest that inactive, nonfunctional natural drug resistance modules can also regain function upon drug treatment, quickly converting drug-sensitive cancer cells or microbes in drug-resistant ones.

The research is supported in part by a National Institutes of Health (NIH) National Institute of General Medical Sciences grant (R35 GM122561), the Laufer Center, and a Swiss National Science Foundation Ambizione grant.

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About Stony Brook UniversityStony Brook University, widely regarded as a SUNY flagship, is going beyond the expectations of what todays public universities can accomplish. Since its founding in 1957, this young university has grown to become one of only four University Center campuses in the State University of New York (SUNY) system with over 26,000 students, more than 2,700 faculty members and 18 NCAA Division I athletic programs. Our faculty have earned numerous prestigious awards, including the Nobel Prize, Pulitzer Prize, Indianapolis Prize for animal conservation, Abel Prize and the inaugural Breakthrough Prize in Mathematics. The University offers students an elite education with an outstanding return on investment: U.S.News & World Report ranks Stony Brook among the top 40 public universities in the nation. Its membership in the Association of American Universities (AAU) places Stony Brook among the top 62 research institutions in North America. As part of the management team of Brookhaven National Laboratory, the University joins a prestigious group of universities that have a role in running federal R&D labs. Stony Brook University fuels Long islands economic growth. Its impact on the Long island economy amounts to $7.38 billion in increased output. Our state, country and world demand ambitious ideas, imaginative solutions and exceptional leadership to forge a better future for all. The students, alumni, researchers and faculty of Stony Brook University are prepared to meet this challenge.

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Study Shows Evolution Turns Genes Back On to Regain Function - Stony Brook News

A 17-gene expression signature to distinguish patients who are likely to achieve long-term remissions following front-line FCR chemoimmunotherapy from…

In this paper, Carmen D Herling, Department I of Internal Medicine, Center for Integrated Oncology, Aachen-Bonn-Cologne-Duesseldorf, Cologne, Germany, and colleagues hypothesized that the duration of response to FCR chemoimmunotherapy depends on differences in the expression of protein-coding genes. Therefore, they developed and validated a 17-gene expression signature to identify patients that might achieve durable remissions following front-line FCR chemoimmunotherapy.

Study design and patients1

Results1

After the gene expression data analysis for the MDACC cohort, the authors identified 1,136 probes associated with time to progression. Using these probes, patients with similar gene expression patterns were divided into favorable, intermediate, and unfavorable prognosis subsets. The intermediate prognosis and unfavorable prognosis subset had a shorter time to progression compared with patients in the favorable subset.

Genes highly expressed in unfavorable cases (n= 424) were associated with metabolic pathways, including oxidative phosphorylation and ribonucleoside metabolism. Genes highly expressed in favorable or intermediate cases (n= 401) encoded products involved in ATP binding, purine ribonucleoside triphosphate binding, nucleic acid binding, and DNA-template transcription.

The authors developed a prognostic model with 17 genes to distinguish IGHV-unmutated patients that had an intermediate outcome from those with an unfavorable outcome after front-line FCR therapy. The development process included:

These 17 genes were validated in 109 patients with an IGHV-unmutated status from the CLL8 cohort. In this cohort, patients classified as high risk (unfavorable prognosis; median time to progression of 39 months [IQR 2269]) had a hazard ratio of 1.90 (95% CI 1.183.06; P = 0.008) compared with low-risk (intermediate prognosis; median time to progression of 59 months [IQR 2884]) patients. Of the 17 genes, 13 came from the cluster of genes highly expressed in unfavorable cases with shorter time to progression, and increased expression corresponds to increased risk of progression. Three of the 17 genes came from the cluster of genes highly expressed in favorable or intermediate cases with longer time to progression and increased expression corresponds to decreased risk.

Conclusions

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A 17-gene expression signature to distinguish patients who are likely to achieve long-term remissions following front-line FCR chemoimmunotherapy from...

Transarterial Chemoembolization and Sorafenib Combined with Microwave | CMAR – Dove Medical Press

Jia-Yan Ni,13 Hong-Liang Sun,1,2 Jiang-Hong Luo,1,2 Xiong-Ying Jiang,1,2 Dong Chen,1,2 Wei-Dong Wang,1,2 Yao-Ting Chen,1,2 Jin-Hua Huang,3 Lin-Feng Xu1,2

1Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province 510120, Peoples Republic of China; 2Department of Interventional Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong Province 510120, Peoples Republic of China; 3Department of Minimally Invasive Interventional Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Cancer for Cancer Medicine, Guangzhou, Guangdong Province 510060, Peoples Republic of China

Correspondence: Jin-Hua HuangDepartment of Minimally Invasive Interventional Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Cancer for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangdong Province 510060, Peoples Republic of ChinaTel +86-20-87343447Email huangjh_sysucc@163.comLin-Feng XuGuangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Department of Interventional Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, 107 Yanjiang Road West, Guangzhou, Guangdong Province 510120, Peoples Republic of ChinaTel +86-20-34078680Email xu_lin_feng@163.com

Purpose: The aim of this study was to investigate the safety and efficacy of transarterial chemoembolization and sorafenib (TACE-S) combined with microwave ablation (TACE-S-MWA) for the treatment of patients with advanced primary hepatocellular carcinoma (HCC).Methods: Between January 2015 and December 2018, 152 consecutive advanced HCC patients, who underwent TACE-S-MWA (MWA group, n=77) or TACE-S (Non-MWA group, n=75), were investigated. Overall survival (OS), time to progression (TTP) and safety were compared between the two groups. Prognostic factors were analyzed using the Cox proportional hazard regression model.Results: Baseline patient characteristics were balanced between the two groups. MWA group was associated with a higher OS (median, 19.0 vs 13.0 months; P<0.001) and a longer TTP (median, 6.0 vs 3.0 months; P<0.001) compared with non-MWA group. Multivariate analyses showed that portal vein tumor thrombosis (PVTT) (P=0.002), duration of sorafenib (P<0.001), and MWA treatment (P=0.011) were independently associated with OS. MWA treatment strategy (P<0.001) was a significant predictor of TTP. There were no treatment-related mortalities in either group. The rates of minor complications (42.9% vs 38.7%, P=0.599) and major complications (1.29% vs 1.33%, P=0.985) in the MWA group were similar to those in the non-MWA group.Conclusion: TACE-S-MWA was safe and effective for advanced primary HCC. TACE-S-MWA resulted in better OS and TTP than did TACE-S for treatment of patients with advanced primary HCC.

Keywords: hepatocellular carcinoma, transarterial chemoembolization, microwave ablation, sorafenib, survival

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Transarterial Chemoembolization and Sorafenib Combined with Microwave | CMAR - Dove Medical Press

Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host | COPD – Dove Medical Press

Nisha Kurian,1 Taylor S Cohen,2 Lisa berg,3 Erica De Zan,3 Gabriel Skogberg,4 Stefan Vollmer,3 Engin Baturcam,3 Petter Svanberg,5 Britta Bonn,5 Paul D Smith,6 Outi Vaarala,3 Danen M Cunoosamy3

1Respiratory Inflammation and Autoimmune (RIA) Precision Medicine Unit, Precision Medicine, Oncology R&D, AstraZeneca, Gothenburg, Sweden; 2Microbial Sciences, Medimmune, Gaithersburg, MD, USA; 3Translational Science and Experimental Medicine, Research and Early Development, RIA, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden; 4Bioscience, Research and Early Development, RIA, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden; 5Drug Metabolism and Pharmacokinetics, Research and Early Development, RIA, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden; 6Bioscience, Oncology R&D, AstraZeneca, Cambridge, UK

Correspondence: Nisha KurianRespiratory Inflammation and Autoimmune (RIA) Precision Medicine Unit, Precision Medicine, Oncology R&D, AstraZeneca, Gothenburg, SwedenTel +46 72 197 9662Email Nisha.e.kurian@astrazeneca.com

Background: Unlike p38 mitogen-activated protein Kinases (MAPK) that has been extensively studied in the context of lung-associated pathologies in COPD, the role of the dual-specificity mitogen-activated protein kinase kinase (MEK1/2) or its downstream signaling molecule extracellular signal-regulated kinases 1/2 (ERK1/2) in COPD is poorly understood.Objectives: The aim of this study was to address whether MEK1/2 pathway activation is linked to COPD and that targeting this pathway can improve lung inflammation through decreased immune-mediated inflammatory responses without compromising bacterial clearance.Methods: Association of MEK1/2 pathway activation to COPD was investigated by immunohistochemistry using lung tissue biopsies from COPD and healthy individuals and through analysis of sputum gene expression data from COPD patients. The anti-inflammatory effect of MEK1/2 inhibition was assessed on cytokine release from lipopolysaccharide-stimulated alveolar macrophages. The effect of MEK1/2 inhibition on bacterial clearance was assessed using Staphylococcus aureus killing assays with RAW 264.7 macrophage cell line and human neutrophils.Results: We report here MEK1/2 pathway activation demonstrated by increased pERK1/2 staining in bronchial epithelium and by the presence of MEK gene activation signature in sputum samples from COPD patients. Inhibition of MEK1/2 resulted in a superior anti-inflammatory effect in human alveolar macrophages in comparison to a p38 inhibitor. Furthermore, MEK1/2 inhibition led to an increase in bacterial killing in human neutrophils and RAW 264.7 cells that was not observed with the p38 inhibitor.Conclusion: Our data demonstrate the activation of MEK1/2 pathway in COPD and highlight a dual function of MEK1/2 inhibition in improving host defense responses whilst also controlling inflammation.

Keywords: exacerbation, infection, alveolar macrophage, p38 MAPK, steroid, transcriptomics, sputum

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Dual Role For A MEK Inhibitor As A Modulator Of Inflammation And Host | COPD - Dove Medical Press

Jipmer conducts JIPP 2019 – United News of India

More News26 Nov 2019 | 2:49 PM

Thiruvananthapuram, Nov 26 (UNI) National Institute of Speech and Hearing (NISH) has celebrated the 70th Constitution Day at its campus in Akkulam on Tuesday.

Sabarimala, Nov 26 (UNI) As many as 8 Ayyappa devotees were injured, two of them seriously, when a huge tree fell on them while they were trekking on the Chandranandan road near Marakkuttam, here in the wee hours on Tuesday.

Mangaluru, Nov 26 (UNI) ACP Squad in an operation arrested an Indian Army imposter Manjunath Reddy who was posing himself as Indian Army Junior Commissioned officer, at a his residence in Suratkal.

Mysuru, Nov 26 (UNI) Karnataka Chief Minister BS Yediyurappa on Tuesday expressed confident that BJP would sweep the upcoming 15 Assembly seats and that would put an end to all talks around mid-term polls in the state.

Udupi, Nov 26 (UNI) District Administration and police have warned devotees and tourists about fake website created by miscreants in the name of Sri Mookambika Temple at Kollur.

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Jipmer conducts JIPP 2019 - United News of India

Churro vendor controversy: Separating The Facts From The Political Correctness – Pressenza, International Press Agency

By Robert Lederman, President of A.R.T.I.S.T.

As you have no doubt seen and heard, two recent arrests of immigrant women vending churros (a long donut like pastry) has resulted in a huge controversy. Ive linked 3 of the many articles on this below my personal comments.

The media and elected officials have feigned outrage over the 2 arrests and they are linking the arrests to 2 new proposed vending laws which, if passed, will forever change NYC vending for the worse. The 2 arrests are being used as proof that all the vending laws need to be radically changed. Need I mention that the Street Vendor Project, a City Council funded front group that has spent years trying to eliminate the rights of street artists, helped write these 2 proposed laws and is using all of its resources to get them passed? The City Council bill was cooked up by by a giant food vending corporation [MOVE SYSTEMS] funded by Wall St billionaires, the Street Vendor Project and a corrupt City Council Speaker with direct ties to the food company. [for details see: https://www.facebook.com/stopintro1303/ ]

Suddenly, both the media and the elected officials are pretending that vendor arrests are either unknown or rarely happen and they are further pretending that this was some kind of racist attack by the NYPD on Hispanic vendors.

The reality is that all vendors experience some degree of harassment. There are thousands of vendors arrested in NYC each year and tens of thousands summonsed. These women had many previous summonses for vending in the subway and simply refused to stop doing it. These were legitimate police actions not harassment.

One can feel sympathy for anyone being arrested or summonsed while at the same time recognize that there are vending laws for a reason. Food vending laws are, to my thinking, the most reasonable vending laws.

These 2 women were unlicensed, had no food vending permit, a completely illegal cart and were vending in the subway, which is illegal for all vendors regardless of what they sell. If there is any type of vending that actually needs to be closely regulated, it is food vending.

A single food vendor with a communicable disease, a dirty cart or who mishandles food, can create an epidemic. Thats why food carts require a vending license, a food cart permit and a certification in proper food handling. They dont want food vending in the subway because NYC subways already have a huge rat problem and food vending will make it much worse. Imagine trying to get into a subway car or out onto a rush hour subway platform that is crammed with food carts.

For most of my life I worked as an illegal vendor. I am not opposed to anyone getting a vending license; but I am opposed to fake vending reform that pretends to be about helping poor vendors but is actually about helping the biggest and wealthiest food vending corporations.

The 2 proposed laws are a scam. They want to completely eliminate any cap on how many food vendors there can be and make getting the license and permit very easy. Sounds good right?

But theres a catch.

A legal food cart has to have hot and cold running water. They cost anywhere from 5 to 50 thousand dollars. The cart and the food has to be stored in an authorized commissary, which would cost many thousands more. And, they still wont be able to vend in the subway, let alone vend from a cardboard box on top of a shopping cart.

Whats more, these proposed laws provide that a vendor getting 4 summonses loses their license; the City Council bill puts all vending decisions into the hands of the BIDs; and the State law gives cities and parks the right to create any new limits on vending they like.

Whats the real agenda behind these 2 proposed laws? Is it about helping poor immigrant vendors?

Apart from scoring points for political correctness, its about helping giant food corporations take over all vending. A food vending company can only own 1 food vending permit. By increasing the number of permits out there (removing the cap) these food vending corporations can temporarily buy up thousands of permits from the vendors who obtain them, exactly as they do now with a huge black market in food vending permits.

Once the streets are completely overrun with thousands of new food vendors, the City will have no choice but to create a concession system, exactly as exists throughout NYC Parks, where 2 or 3 companies own every food cart and stand. Immigrant employees paid less than minimum wage run these stands. Thats the wonderful future the elected officials are setting up for the vendors they are pretending to help.

When you see these hypocrite elected officials posing as champions of the vendors, dont forget that it is these exact same pols who wrote the vending laws and who mercilessly pressure the police to enforce them.

The very same media outlets pretending to be outraged about these arrests, such as the NY Times, have spent decades demanding crackdowns on vending. In fact, the NY Times started the Times Sq BID, one of the most anti-vending organizations in NYC.

One might ask, how is this different from the City arresting artists in the hundreds from 1993-2001? Didnt we protest hundreds of times? didnt we try to change the vending laws?

The difference is that artists were already considered to be First Amendment protected by the NY District Attorney as early as 1993. Every one of those arrests were illegal and unconstitutional. There is no Constitutional right to vend food in the subway. Moreover, we changed the vending laws in such a way as to help all vendors.

In fact, under the rights we won, immigrant vendors can legally sell books, art, cds, dvds and other First Amendment related materials without any license or permit.

These proposed bills are poison to every form of vending.

Please stop exploiting immigrants to make yourselves appear to be enlightened public servants. You are fooling no one.

NY Times: Handcuffed for Selling Churros: Inside the World of Illegal Food Vendors

Daily News: Cries for justice on the subways as NYPDs crackdown on Brooklyn churro vendors brings a second arrest

[NOTE: The writer has vended in NYC since 1962 as both a street artist and a food vendor]

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Churro vendor controversy: Separating The Facts From The Political Correctness - Pressenza, International Press Agency

A ray of Arab-Israeli hope and other commentary – New York Post

Foreign desk: An Arab-Israeli Ray of Hope

Thirty prominent public figures from 15 Arab countries, some facing serious personal security issues, gathered in London last week to repudiate the boycott, divestment and sanctions movement against Israel and demand their nations establish direct civil relations with the Jewish state, reports Jenni Frazer at the Jewish Journal. Attendees included Mohammed Anwar Sadat, a member of the Egyptian Parliament and a nephew of former President Anwar Sadat; former Kuwaiti Minister of Information Sami Abdul-Latif Al-Nisf; as well as other religious and political notables. The group recounted personal stories about good relations with Jews and deplored terrorism, brainwashing kids against Israel and politicizing Islam. Former US diplomat Dennis Ross called the participants courageous and a ray of hope. And while no government was officially involved, the views expressed are bound to resonate throughout the Middle East.

2020 watch: Ivy League Folly Is How Trump Wins

Saturdays Yale-Harvard football game was delayed for about an hour because of students protesting climate change on the field at the end of halftime, Mediaites John Ziegler fumes and it was just the kind of extreme political correctness that will get President Trump re-elected come next year. The protesters deliberately timed their action to waste maximum time and gain maximum media attention. Instead of cracking down, however, officials at Yale, where the game was held, treated the radicals with kid gloves, the kind their spoiled, affluent cohort has come to fully expect. And while voters wont remember this particular debacle when they step into the booth next year, Trumps political rocket ship is fueled by the extremely negative reaction Middle America has to political correctness. All the brilliant Yalies did was add a bit more gas to his tank.

City desk: Prohibit Parking To Save Space

While critics bemoan any change to street parking in New York City, Connor Harris argues in City Journal that the systems familiarity blinds residents to the fact that todays system is inefficient, anti-free-market and unfair. For example, the city could install hygienic municipal dumpsters on reallocated parking spots, preventing garbage from piling up on trash-collection days, or convert spots to bus lanes and loading zones. Also, cheap street parking exists by government fiat: Letting the free market decide what to do with a space could raise its price or convert it to more productive uses. Fact is, even without street parking, New Yorks drivers could easily afford the true cost of driving and non-drivers would be better off.

Culture critic: Dolly Doesnt Need Times Lectures

A recent New York Times profile of Dolly Parton sneered at the country-music legends supposed failure to make the slightest hint of a political statement which should win the paper some sort of prize for statements that are best at missing what is in plain sight, snarks the Walter Olson at Cato. Partons positive persona and enormous charitable contributions make a perfectly legitimate political statement, as one Twitter correspondent told Olson. Besides, Olson notes, shes written plenty of songs about poverty, about the thing between men and women and about responding to bad treatment with forgiveness and magnanimity. Or as another tweeter put it: Dolly Partons life is a political statement for those with eyes to see and ears to hear.

Brexit watch: A Collapsing Remain

Party loyalty has blurred in Britain since the Brexit referendum, The Spectators James Forsyth reports, but feelings about the referendum are almost stronger than they were on June 23, 2016, the day of the original vote, with pro-Leave and pro-Remain the strongest political forces in Britain. Remainers, however, have been unable to unite behind any one party or leader, and that lack of cohesion has proved fatal. Most damaging: Labour party leader Jeremy Corbyn is determined to maintain ambiguity in Labours Brexit position, limiting a Remain alliance to minor parties. Unless Remainers can turn things around in the next three weeks, their cause will be lost.

Compiled by The Post Editorial Board

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A ray of Arab-Israeli hope and other commentary - New York Post

Trump Tells Allies He Wants Absolved War Criminals to Campaign for Him – The Daily Beast

If Donald Trump gets his wish, hell soon take the three convicted or accused war criminals he spared from consequence on the road as special guests in his reelection campaign, according to two sources who have heard Trump discuss their potential roles for the 2020 effort.

Despite military and international backlash to Trumps Nov. 15 clemency fallout from which cost Navy Secretary Richard Spencer his job on Sunday Trump believes he has rectified major injustices. Two people tell The Daily Beast theyve heard Trump talk about how hed like to have the now-cleared Clint Lorance, Matthew Golsteyn, or Edward Gallagher show up at his 2020 rallies, or even have a moment on stage at his renomination convention in Charlotte next year. Right-wing media has portrayed all three as martyrs brought down by political correctness within the military.

He briefly discussed making it a big deal at the convention, said one of these sources, who requested anonymity to talk about private conversations. The president made a reference to the 2016 [convention] and where they brought on-stage heroes like former Navy SEAL Marcus Luttrell, who refused to execute detained civilians ahead of a devastating Taliban attack.

Former Army Lt. Lorance was sentenced to 19 years in prison in 2013 for murder after ordering his soldiers in 2010 to fire on three unarmed Afghan men riding a motorcycle, killing two of them. He walked out of military prison at Fort Leavenworth on Nov. 15. Next month, former Green Beret Maj. Golsteyn was supposed to stand trial for the murder of an unarmed Afghan man whom he told the CIA he killed in the belief the man was a Taliban bombmaker. Golsteyn, who allegedly burned the mans corpse, pleaded not guilty to the murder; the Green Berets stripped Golsteyn of his Special Forces tab. Lorance and Golsteyn were both causes clbre in certain military circles and among their right-wing supporters, as was Navy SEAL Chief Gallagher.

A military jury this summer acquitted Gallagher for the murder of a wounded teenage fighter for the so-called Islamic State. The case, which both featured Trumps conspicuous intervention boosting Gallagher and serious prosecutorial misconduct, began, like Lorances, with Gallaghers own platoonmates reporting his conduct. Against Gallaghers denial, two SEALs testified seeing the senior SEAL chief stab the wounded teenager in the neck. Gallagher, along with lower-ranking SEALs, took a photo with the corpse and texted it with the caption good story behind this, got him with my hunting knife. But another SEAL reversed his testimony to say that he, not Gallagher, killed the wounded teenager by closing off an inserted breathing tube. Gallaghers only conviction was for taking the photo and he was released for time served. Trump pardoned Lorance and Golsteyn and reversed Gallaghers demotion in rank.

Opposition to the clemency was reportedly ardent in the senior ranks of the Pentagon and the uniformed military. The Navy opted to proceed with an internal review over stripping Gallagher of his Trident pin, which symbolizes his place in the elite commando ranks. Trump, via tweet, insisted that the Trident board not happen, and publicly clashed with Spencer, his Navy secretary, who took the position that the board ought to proceed despite Trumps tweets.

Yet late on Sunday afternoon, Defense Secretary Mark Esper announced that Spencer had made a secret entreaty to Trump that would have rendered the board for show and ensured Gallagher retired at full SEAL rank and pension. Espers account was in such stark opposition to Spencers positions in the case that several in military circles, while acknowledging the murkiness around the entire episode, consider it to be untrue. A Navy Reserve officer who requested anonymity doubted that a true account would emerge from the administration, but said the current messy narrative is not credible.

Esper, in a statement, said he was deeply troubled by Spencer allegedly routing around the defense secretary to take a position the Pentagon conceded was contrary to Spencers public position. That line holds Spencer was fired despite secretly agreeing with Trump on Gallaghers disposition. And Esper also confirmed he will do the exact thing that Trump and, allegedly, Spencer, sought: permitting Gallagher to retire as a Navy chief, and a SEAL. Esper, astonishingly, told reporters Monday that Trump had ordered the defense secretary to ensure Gallagher keeps his Trident, rendering moot the Navys Trident board proceeding.

In irreconcilable contrast to that account, Spencer said in a scorching resignation letter that Trump had jeopardized the rule of law within the military and he could not in good conscience carry out Trumps order to the Navy on Gallagher.

The Constitution, and the Uniform Code of Military Justice, are the shields that set us apart, and the beacons that protect us all, Spencer wrote. Unfortunately it has become apparent in this respect that I no longer share the same understanding with the Commander in Chief who appointed me, in regards to the key principle of good order and discipline.

Robert Work, a former deputy defense secretary in the Obama and Trump administrations with deep ties to the Navy, said that while he had no first-hand knowledge of the debacle, he believed Spencer.

I take Spencers resignation letter as the truth, Work told The Daily Beast. Its one of those things where well never know the real truth. He continued: I think Spencer just felt he had to do this. Its extremely unfortunate.

Eugene Fidell of Yale Law School, one of the foremost experts in U.S. military justice, cautioned that what exactly occurred remains unclear. But Fidell said it had already done enormous damage to the Navys fidelity to the law.

Esper has committed the very offense he has accused Spencer of having committed, though in Espers telling, it happened behind [Espers] back, Fidell said. If Spencer did this, Spencer is in the wrong. Esper doing this makes Esper in the wrong. Either way, its a body blow to the rule of law in the Department of the Navy.

Esper received a political boost from the chairman of the Senate Armed Services Committee, James Inhofe (R-OK), who had clashed with Spencer on other issues. Both Secretary Esper and President Trump deserve to have a leadership team who has their trust and confidence, Inhofe said in a statement.

But in the Democratic-controlled House, the vice chairman of the armed-services committee, Maryland Democrat Anthony Brown, an Iraq veteran, came to Spencers defense. It is a dark day when the president stands with those accused of committing war crimes over a man like Secretary Spencer, Brown said in a statement.

Neither the White House nor Trump campaign spokespeople responded to requests for comment as of press time.

While the war-crimes pardons were not Trumps first in May, he granted clemency to convicted murderer Michael Behenna, an Army lieutenant who in 2008 killed an unarmed, naked Iraqi man during an unauthorized interrogation Trump had fought the Pentagon for more than half a year for the pardons. Promoting them was Pete Hegseth, an Iraq War veteran and a Fox & Friends co-host who had aggressively and personally lobbied Trump since at least March to take such action.

In fact, Lorance, just days after receiving his pardon, appeared on Hegseths Fox News show and effusively lauded Trump, saying, I love you, sir, and telling the president, you are awesome! Days before Spencers firing, Lorance also said on the Fox program that President Trump needed a better team around him, as well as more people watching your back. Gallagher, in a statement tweeted by Hegseth, called Trump a true leader and exactly what the military needs.

Gallaghers attorney Tim Parlatore told The Daily Beast on Monday afternoon that shortly after President Trump called his client to inform him that the rank reinstatement was coming, Gallagher held a conference call with members of his family and Parlatore, to inform them of the news. The lawyer said he then joked on the phone call, Theres no quid pro quo? He didnt ask you to investigate the Bidens?

Gallagher then laughed and replied, No, he just gave it to me! Parlatore recalled, adding that since that phone call, no quid pro quoa clear reference to the impeachment inquiry bedeviling the Trump presidencyhas become a little inside joke between Gallagher and Parlatore.

Yet even Trump allies believe that absolving convicted or accused war criminals of their actions consequences has done substantial damage to the military.

I think more often than not when something like this happens in the administration, a lot of people hyperbolically state that this is undermining our institutions or destroying our democracy, said one ally of the Trump administration who works on military issues. Most of the time it is over-the-top nonsense, but not in this case. This whole thing is a mess and it will undermine good order and discipline in the SEAL community when it is badly needed after a string of incidents involving severe misconduct.

This person added, Pete Hegseth, as a field-grade Army officer, should know what he is doing is wrong, but either doesnt understand the negative repercussions this will have for officers and senior [non-commissioned officers] trying to maintain good order and discipline in their units, or doesnt care. Its shameful and this is truly a black mark on the Trump administrations national-security record.

Editors note: This story has been updated to correct the nature of the photo of Gallagher and the corpse.

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Trump Tells Allies He Wants Absolved War Criminals to Campaign for Him - The Daily Beast

The move to cancel Gauguin could kill off Western culture – New York Post

At a current Paul Gauguin exhibition at Londons National Gallery, visitors are warned that the famous French painter had sexual relationships with young girls, including two with whom he fathered children.

A wall text notes, Gauguin undoubtedly exploited his position as a privileged Westerner [in French Polynesia] to make the most of the sexual freedoms available to him.

An audio guide even raises the question, Is it time to stop looking at Gauguin altogether?

This is what art appreciation has come to: a PC prism through which a painting, a work of literature or even a popular song must be scrutinized for racism, sexism, gender bias or just plain hurt feelings.

New York museums havent banned anything yet. But look out: Metropolitan Museum of Art director Max Hollein told The New York Times that, Art cannot solely be perceived in regard to its beauty and craftsmanship. You also have to evaluate it in light of its political messages.

If you say so, chief. I thought most human beings turned to art not for ideological hectoring but for the joy of beauty and insight into the human condition whether from Dante, Shakespeare or Springsteen.

The warnings against Gauguin are another step toward excommunicating every Western creative talent from the realm of permissible enjoyment. If left unopposed, the PC fascists will inevitably ban everything by Western-world artists, writers and musicians due to perceived sensitivities or colonialist violations.

Why stop with Gauguin? Another revered European painter, Caravaggio, was a murderer, a pimp and a sex abuser of children. His Victorious Cupid and St. John the Baptist depict a naked young boy with whom Caravaggio is believed to have been having sex, according to Guardian critic Emine Saner.

By any consistent standard of political correctness, Shakespeares got to go. While he was no pedophile, his play The Taming of the Shrew celebrates misogyny. Othello is full of racist tropes. Shylock in The Merchant of Venice betrays a deeply anti-Semitic spirit.

By that token, Vladimir Nabokov should be exiled to Siberia for Lolita. Though its widely recognized as one of the 20th centurys greatest novels, his character Lolita is 12 years old when narrator Humbert Humbert falls for her. He beds and ultimately loses her to a romantic rival, whom Humbert enthusiastically bumps off. Burn the book and ban the movie adaptations!

Mark Twains masterpiece Huckleberry Finn has barely survived the onslaught of racism charges. Its been dropped from some campus reading lists over a character whose nickname is the N-word. Shouldnt Twain, who wrote the novel as an anti-racism saga more than 120 years ago, have predicted that the slur widely used by whites in the pre-Civil War South would be deemed impermissible in a work of fiction in the 21st Century?

If Huck Finn needs condemnation, so do the poems of Walt Whitman, who referred to black people as baboons. Or the novels of Joseph Conrad, whose racism was implicit in the African fable Heart of Darkness.

Im overreacting, right? Well, last year, Kate Smith was dropped from the Yankee Stadium soundtrack for having once, at 24, sung a racist tune at her record companys behest at a time when segregation was the law of the land in many states. More recently, a few busybodies changed the teasing lyrics to Baby Its Cold Outside lest the original be misconstrued as a lead-up to rape. (Of course, rap artists who celebrate actual sexual subjugation of women see 50 Cents P.I.M.P. get a free pass.)

If the PC purity test continues to rule, well be left with empty bookshelves and bare-wall galleries. Art may survive only if its twisted to politically correct ends like the Broadway staging of Oklahoma! thats so warped from the original, its been ridiculed as Wokelahoma.

Its time for some brave pushback to arrest the slide or woke me when its over.

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The move to cancel Gauguin could kill off Western culture - New York Post

Editorial: Remembering the 1898 coup in Wilmington, NC – News – Burlington Times News

For decades, much of Wilmington was in denial about what happened in the city on Nov. 10, 1898. Perhaps worse, it wasn't that long ago that many residents had not even heard of the Port City's coup d'etat.

We hope that the denial and lack of awareness of the coup are themselves becoming history. Earlier this month, the state of North Carolina unveiled a highway historical marker in front of the old Wilmington Light Infantry armory building at Fourth and Market streets, the site where an armed band of white supremacists gathered and then marched to destroy a black-owned newspaper.

A marker already stands to Alex Manly, the crusading African-American editor whose offices were torched. The new marker, however, nudges matters a few steps further. It refers to those shameful events not as a "riot" or "race riot," as earlier sources had, but as what it really was a coup that is generally considered the only successful overthrow of a government in U.S. history.

This is not just semantics or political correctness. This underlines bald, brutal fact.

A "race riot" implies that Wilmington's black residents were, if not the instigators, at least up to something. No. The event was in fact a coup d'etat.

Usually it means that some tinpot generals have overthrown the government and seized power in some distant country where democracy hasn't taken firm root.

Here, it covers a conspiracy led by some of the city's key power brokers. That conspiracy forced the legally elected mayor and aldermen of Wilmington, a biracial body, to resign, one by one, essentially by gunpoint. They were then replaced by an all-white slate.

An unknown number of African Americans were killed in the process. As far as is known, no white people lost their lives.

The leaders of this coup later joined other white supremacists in North Carolina in enacting Jim Crow laws that instituted racial segregation and deprived most black citizens of the right to vote for more than half a century.

The legacy of this coup put a chill on Wilmington life that lasted for close to a century and still exists today.

More than 120 years later, some North Carolinians have seen their voting rights targeted by election laws and their political clout diminished by gerrymandering.

Fortunately, North Carolina now seems to be heading in a different direction. The courts have called foul on the excesses of gerrymandering. A new law with bipartisan support, signed by Gov. Cooper, cracks down on the practice of "harvesting" absentee ballots and further guarantees early voting is available on the Saturday before Election Day.

The long-overdue 1898 marker is up, but the fight isn't over. As the coup d'etat of 1898 taught us, foreign foes are not our only menace.

Star News of Wilmington, a Gannett publication

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Editorial: Remembering the 1898 coup in Wilmington, NC - News - Burlington Times News

Jay Roach vs Todd Phillips on Whether ‘Woke Culture’ Is Killing Comedy Movies – TheWrap

Everyone is too touchy, Phillips, the director of Joker, tells me but Bombshell filmmaker Roach feels otherwise

I have been obsessing lately over the decline of big-screen comedies and the fact that some of the leading comedy directors of our time have turned serious in recent years, from Hangover creator Todd Phillips with his dark global hit Joker to Jay Roach, going from Austin Powers to Game Change and now Bombshell.

This fall, Joker has powered its way to $1 billion at the global box office, the benchmark usually set by superhero sagas rather than social commentary, while the mid-December release of Bombshell takes on sexual harassment at Fox News. Neither film is funny, and both are ambitious swings by two top directors.

I raised the issue with each of them in recent interviews. Phillips has been quoted saying that woke culture, a hypersensitive and reactive political correctness, has driven people like him from the comedy genre. He went deeper on this with me. Everyone is too touchy, Phillips told me. Everyone is so effing touchy.

Roach had a different perspective. He called on the studios to loosen their purse strings, to fund comedies at the levels of years past so artists like him can find the excitement in ambitious comedy again. He said the studios are to blame for putting comedies into a death spiral.

Also Read: Director Todd Phillips on Making 'Joker': Art Is 'Meant to Be Complicated'

Jay Roach (Photo by Corina Marie Howell for TheWrap)

Both views are a study in a changed landscape in Hollywood. Comedies from Stuber to Holmes and Watson have faltered at the box office in the last year, leading to both hand-wringing and theories about why this is the case.

When I asked Phillips why some of my favorite comedy directors including Roach and Adam McKay (Anchorman, The Big Short) are turning to more serious-minded material, he told me, somewhat aggressively: Do you want me to tell you why it is? Comedy is based in truth. Truth has become offensive. You get crippled trying to do comedy if truth is offensive. I can think of 10 jokes from the nine studio comedies Ive made that would cause an issue on Twitter nowadays.

Then he cited Dave Chappelles latest stand-up special, released on Netflix in August to almost immediate outcry over jokes about transgender people as well as abuse allegations against Michael Jackson and R. Kelly. Dave might have done the most brilliant hour of stand-up called Sticks & Stones. Its literally called Sticks & Stones think about it, Phillips said. Hes getting this whole thing where the far left sounds like the far right when it fits their agenda.

In making Joker, Phillips said, I was like, OK, let me go over here and play in this sandbox a little bit. Maybe with Jay and Adam, its politics. Maybe its me with messing around with comic book movies, messing up that sandbox. Im not speaking for Jay and Adam, but for me the things people like about The Hangover the outrageousness or the things people like about Old School the irreverence is based in truth. If truth is now offensive, which it seems to be, lets just put that aside for a minute.

Also Read: 10 Comedy Directors Who Went Serious, From Jay Roach to Todd Phillips (Photos)

Todd Phillips with Joaquin Phoenix on the set of Joker (Warner Bros.)

When I spoke to Roach earlier this month, he disagreed with Phillips. Its not political correctness thats killed big-screen comedy, Roach said, its the studios business model.

I do wonder whats happened to the studios ability to rally the right people, get the right scripts and make comedies, he said. And one of the things that I have noticed is that theres been a tremendous trend, its kind of a self-perpetuating spiral downwards in budget on comedies: They dont do quite so well, then you make them come in for less, then they do less well.

The result, said Roach, is a vicious cycle. It takes money and time and room for actors to try things and experiment and fail and fail again, and fail again and then you succeed, he said. The studios feel like well just keep making them for lower money and that reduces the risk. But Ive found, in the comedies I made because we had 50 days, or 55 days of shooting, the actors could try things and we would cut at a three-hour movie and just use the best half of it. Now you only get to shoot an hour-and-a-half movie.

So how do you make a successful movie comedy? You get really funny people and hire possibly expensive actors to come in and do their best work and give them a ton of time to do it and then let them go for some spectacle, he said. I remember when Something About Mary came out, it was around the time that our Austin films came out, I was like, Oh, my God, Im so happy they did this and that it made a lot of money because it meant we could keep doing that.

Also Read: A 'Bombshell,' 'Parasite' and Brutality Are Shaking Up the Oscar Race

Roach admitted that the current state of the U.S. is driving him to focus on politics. I dont have anything against going back and doing comedy. Im just for some reason driven, just freakin driven, to understand whats going on in our world, he said. And these films are what make me work twice, three times as hard as I might on something else. (That said, he added, If I had a great comedy script right now and it had great characters and was about something, I would be so quick to do it.)

While it might not be a shock that Phillips and Roach have matured into more sophisticated subjects, it is surprising that Hollywood has not found a new generation of comedic filmmakers to fill the void.

Phillips insisted that younger directors are finding other mediums. Theres many types of comedies, he said. Theres Austin Powers. Ill laugh at Austin Powers, but thats not my kind of comedy. My type of comedy has always been grounded in reality, and then make the situations absurd. I guess my point is its not a big of leap coming from Hangover or Old School to this (Joker), to me, as it appears for some other people.

So you think what youre doing is safer than comedy?, I asked Phillips. His reply: I did think it was safer than R-rated comedy at this moment.

He went on: I dont mean to be reductive, but these papers like TheWrap and Hollywood Reporter, Deadline, Ive seen articles over the last few years of like, What happened to the R-rated comedy? Thats what it is. Everyone is too touchy. Everyone is so effing touchy.

While some filmmakers get their starts making cheaply made B-movies or horror films, there's a new crop of directors emerging who previously cut their teeth making classic comedies. And while most haven't abandoned their sense of humor entirely, they've finally been recognized at both the box office and awards circuit by veering into prestige pictures. The latest example is Todd Phillips, the director of "Joker," which as the darkly disturbed origin story of the iconic Batman villain is no laughing matter. Here are some other directors who have re-emerged as more than just funny men.

Jay Roach - Comedy Classic: "Austin Powers"/Dramatic Turn: "Trumbo"

Jay Roach helmed not one but two comedy franchises before turning into something of a political wonk and directing the TV movie "Recount" in 2008 about the infamous 2000 election debacle in Florida. He told Vulture that he always admired the directors who find the grey area between comedy and drama like Alexander Payne and Hal Ashby. "Movies that have so much pain and angst yet fully committed humor. Those are the kind of movies I grew up on."

Adam McKay - Comedy Classic: "Anchorman"/Dramatic Turn: "The Big Short"

Movies like "The Big Short" and "Vice" are rooted in comedy and satire because of McKay's intention to capture the absurdity and complexity of a crazy time in recent political and economic history. McKay said in an interview with The New York Times Magazine that he hopes his films capture that murky tone, and that he's not the only funny person suddenly wading into these waters. "Were living in a world with a tone that none of us has ever experienced. Pipe bombs are being sent to the leaders of a political party, and the guy who made Dilbert is saying, You know the bombs were really made by left-wingers because they didnt work, McKay said.

Tom Shadyac - Comedy Classic: "Ace Ventura: Pet Detective"/Dramatic Turn: "Brian Banks"

Despite being one of Hollywood's top comedy directors following Jim Carrey movies like "Ace Ventura," "Liar Liar" and "Bruce Almighty," Tom Shadyac found he couldn't get work in Hollywood after both the bomb of his 2007 film "Evan Almighty" and after he suffered a life threatening concussion in an accident. But he told the LA Times he found a new outlook on life and Hollywood in directing the story of "Brian Banks," a college football star wrongly convicted of a crime.

Todd Phillips - Comedy Classic: "The Hangover"/Dramatic Turn: "Joker"

Todd Philips told Vanity Fair in support of "Joker" that he's left comedy filmmaking entirely after feeling that "woke" culture drove his bro comedies like "Old School," "Road Trip" and most notably "The Hangover" films out of style. "Go try to be funny nowadays with this woke culture, Philips said. There were articles written about why comedies dont work anymoreIll tell you why, because all the f---ing funny guys are like, F--- this s---, because I dont want to offend you. Its hard to argue with 30 million people on Twitter. You just cant do it, right? So you just go, Im out."

Peter Farrelly - Comedy Classic: "Dumb and Dumber"/Dramatic Turn: "Green Book"

Yes, the guy who made "Dumb and Dumber" beat out "Roma" at the Oscars last year. And the tone between comedy and drama that director Peter Farrelly walks with "Green Book" helped his movie get made. Farrelly told Vulture he was able to pitch "Green Book" to studios based on the idea that a racial biopic is actually a buddy, road trip movie. And even though it deals with more dramatic fare, Farrelly still views his film as primarily lighter entertainment. Im sure there will be some criticism that [the film] is not authentic because its not dark enough, Farrelly told Newsweek, But thats not my style. Lighten upits only a movie, right?

Woody Allen - Comedy Classic: "Annie Hall"/Dramatic Turn: "Interiors"

Woody Allen found himself winning Oscars when he went beyond zany farces like "Sleeper" and "Love and Death" to telling more relatable stories like "Annie Hall" that blended comedy, drama and romance. But the prolific director would immediately follow up his Best Picture winner with a strictly dramatic take in the style of Ingmar Bergman films with his 1978 movie "Interiors." Movies like "Another Woman" and "Blue Jasmine" have further shown Allen stepping out of his comedic comfort zone.

Preston Sturges - Comedy Classic: "The Lady Eve"/Dramatic Turn: "Sullivan's Travels"

Preston Sturges, one of the signature directors of Old Hollywood, would likely still be admired today based solely on the success of his screwball comedies like "The Great McGinty" and "The Lady Eve." But he took a step up as an auteur with his 1941 more serious film "Sullivan's Travels." The film even breaks the fourth wall by telling an insider Hollywood story about a talented director who disguises himself as a hobo so he can learn about the true tragedies of the modern world for his next film, only to find he can't ever escape Hollywood and his pigeon-holed place in the business.

Ben Stiller - Comedy Classic: "Zoolander"/Dramatic Turn: "Escape at Dannemora"

In an interview with CBS News, Ben Stiller didn't fault anyone for not knowing what to expect when he took on the job of directing the prison break miniseries "Escape at Dannemora." In fact, Stiller was out of the country shooting "Zoolander 2" when the real life events of the series took place. While he's veered between more dramatic roles as an actor, he teased to CBS News that he might "possibly" be considering retirement from broad comedies altogether.

Paul Feig - Comedy Classic: "Bridesmaids"/Dramatic Turn: "A Simple Favor"

Paul Feig certainly has not strayed from making comedies, but he felt the urge to tackle a Hitchcockian thriller with just a dash of comedic elements with his film "A Simple Favor." In an interview with EW, he explained he's always tried to make genre films and finding the comedy within those tropes. "How do you walk that line where you can push the edge of the tone but you dont spill over out of it so that you take the audience out of it? So this was definitely the biggest tonal tightrope," Feig told EW.

David Dobkin - Comedy Classic: "Wedding Crashers"/Dramatic Turn: "The Judge"

Though music videos and comedies allowed Dobkin to break into the industry, he had been plotting a pivot to drama with the Robert Downey Jr. film "The Judge" as far back as 2006 and before he began production on "Fred Claus," according to an interview with HuffPost. However, his next film finds him squarely back in comedy with the Will Ferrell parody film "Eurovision."

Peter Farrelly, Adam McKay and Ben Stiller have all found awards love after turning to more dramatic movies

While some filmmakers get their starts making cheaply made B-movies or horror films, there's a new crop of directors emerging who previously cut their teeth making classic comedies. And while most haven't abandoned their sense of humor entirely, they've finally been recognized at both the box office and awards circuit by veering into prestige pictures. The latest example is Todd Phillips, the director of "Joker," which as the darkly disturbed origin story of the iconic Batman villain is no laughing matter. Here are some other directors who have re-emerged as more than just funny men.

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Jay Roach vs Todd Phillips on Whether 'Woke Culture' Is Killing Comedy Movies - TheWrap

Does America Have a Gluten Discrimination Problem? – The National Interest Online

Sitting down for a family feast, do you need to gird yourself for battle in the ongoing sociopolitical culture war? In todays hyperpartisan United States, common food products have become proxies for conservative and liberal values. Meat-eating Republicans versus quinoa-loving Democrats. Imported-beer liberals versus domestic-beer conservatives.

Nothing showcases this proxy war better than the rise of gluten sensitivity.

From gluten free water to Jimmy Kimmel clips, gluten sensitivity has permeated the modern American food culture. Despite having no data to support their claims, media voices ranging from the satirical show Portlandia to commentators on Fox News have poked fun at what they characterize as the gluten-intolerant left.

People on the political right, including Ted Cruz, allege that gluten-intolerant West Coast liberals are at the forefront of political correctness.

But is there reality to this perception that liberals cant stomach gluten, while conservatives can wolf it down without complaint?

As researchers of food politics, Bailey Norwood and I often focus on how different market segments perceptions influence their food choices. We decided to investigate the demonization of gluten and our empirical analysis suggests that gluten sensitivity affects people of all political persuasions.

Gluten facts

As physician Robert Shmerling describes, gluten is a protein found in grains such as wheat, barley and rye. It turns up in many common foods, including pizza, cereal and beer. Gluten is what gives dough its elasticity, but it has limited nutritional value itself.

Approximately 0.5% of North Americans have been clinically diagnosed with celiac disease. When people with this autoimmune genetic disease eat gluten, it damages their small intestine, leading to other long-term health effects. The number of documented cases has dramatically risen over the past 30 to 40 years, though researchers arent sure why.

While consumers with celiac and non-celiac gluten sensitivity should definitely avoid gluten, there is no strong scientific evidence that anyone else needs to reduce their gluten consumption. In fact, there is no evidence that would support the notion that gluten-free foods are any healthier than foods filled with gluten for most of the population.

Nevertheless, disagreement rages on regarding whether gluten sensitivity is real and deserves the same universal acceptance that diagnosable diseases like celiac and other established health conditions enjoy.

The contention that gluten sensitivity goes along with liberalism takes the debate even further. If this were true, it would have serious implications for policy decisions and food marketing strategies. It would imply that gluten sensitivity is not strictly a medical condition but a social construct, which would not require the same regulatory concern as other health conditions.

Who actually says no to gluten?

To conduct our analysis, Norwood and I asked 1,086 U.S. consumers four questions about their perceptions of gluten.

We created a gluten aversion index by adding up each persons responses. A score of 4 would indicate that the respondent was not at all gluten avoidant, while a score of 28 would indicate that the respondent was extremely gluten avoidant. After removing the surprisingly high 3.7% of individuals who told us theyd been clinically diagnosed with celiac disease, we looked at the linkage between political ideology and gluten sensitivity.

Contrary to the common stereotype, we found no evidence that the political left is more likely to report being gluten sensitive. In fact, when we divided our sample by preferred president of the past few decades, those who selected Donald Trump were also the most likely to identify as gluten avoidant.

So if progressive liberals arent actually more gluten sensitive, how does the perception take hold?

What psychologists call motivated reasoning is likely a primary culprit. As a time-saving measure, your mind tries to sort each person you encounter into crude buckets based on quick assessments. Once a connection begins to gain traction, it can spread, often leading to misperceptions about individual beliefs and preferences.

Politicization of an ingredient

Its not clear why gluten sensitivity became intertwined with stereotypes about liberal progressives. In fact, even far-right extremist websites such as Infowars have been known to advocate for gluten-free diets.

While we find no evidence of a clear separation between the self-reported gluten sensitivity of liberals and conservatives, it is likely that politically polarizing topics have compromised other food choices. Consider climate change and meat consumption. Vegans and vegetarians are already more likely to identify as liberal. Given the heavy emphasis placed by media on reducing meat consumption as a metric for consciousness regarding climate change, some evidence suggests that meat consumption increasingly can be divided along party lines.

What people eat is one of the most visible decisions they make each day. This is increasingly true as American consumers cook less and eat away from home more. In 2012, Barack Obama won 77% of the counties with a Whole Foods and a meager 29% of Cracker Barrel counties, after all.

Despite Americans political differences, many of us are deeply interested in the foods we consume. Our gluten investigation provides a gentle reminder against simplistic stereotyping around the dinner table.

[ Expertise in your inbox. Sign up for The Conversations newsletter and get a digest of academic takes on todays news, every day. ]

Trey Malone, Assistant Professor and Extension Economist, Michigan State University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

Image: Reuters

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Does America Have a Gluten Discrimination Problem? - The National Interest Online

31 Fabulous Things To Do In Southern California This Thanksgiving Week: Nov. 25-28 – LAist

A lot of Thanksgiving races are on tap for turkey day. (Rex Hammock via Flickr/Creative Commons)

Before you tuck into that Thanksgiving meal, burn some calories at a turkey trot. Madonna wraps her L.A. residency this week. The Never Not Funny podcast tapes a live show. Love Actually Live returns to the stage. The American Cinematheque screens the holiday classic Planes, Trains and Automobiles. A Galaxy Quest documentary celebrates the cult film's 20th anniversary. And a UCB show improvs a Thanksgiving family meal.

MONDAY, NOVEMBER 25; 10:30 P.M. MadonnaThe Wiltern 3790 Wilshire Blvd., Mid-WilshireThe material girl woman wraps her residency at the Wiltern. She's on tour to support her 14th studio album, Madame X, a "love letter to multiculturalism and a testament to Madonna's transformative influence on, and respect for, global culture." This is a no cellphone/no recording device event. COST: Tickets start at $175; MORE INFO

MONDAY, NOVEMBER 25 - SEPTEMBER 2020L.A. MuralsWalt Disney Concert Hall 111 S. Grand Ave., downtown L.A.A new photography exhibition from the Library of Congress showcases murals painted on the streets of L.A. Now on view in the Ira Gershwin Gallery, it features 30 photographs from the archives of photographers Carol M. Highsmith and Camilo Jos Vergara, part of the Library's more than 14 million photographs. COST: FREE; MORE INFO

MONDAY, NOVEMBER 25Tacos. Mezcal. Repeat.JW Marriott Los Angeles L.A. LIVE 900 W. Olympic Blvd., downtown L.A.The hotel's ground floor restaurant, The Mixing Room, becomes Tacos. Mezcal. Repeat. through summer 2020. The menu has been updated with Latin American-inspired flavors and there are more than 60 new mezcals and tequilas to choose from. New dishes include cochinita pibil tacos, beef short rib taquitos and white shrimp ceviche. When the Lakers play at home on Tuesdays, look for their taco Tuuuuuuesday specials.COST: Varies ; MORE INFO

MONDAY, NOVEMBER 25; 8 - 9:30 A.M.Never Not Funny LiveFeinstein's at Vitello's 4349 Tujunga Ave., Studio CityThe Earwolf podcast presents a live taping of the show featuring hosts Jimmy Pardo and Matt Belknap chatting with guest CeCe Pleasants.COST: $15, plus $20 food and beverage minimum; MORE INFO

MONDAY, NOVEMBER 25; 7 - 8 P.M.Chez Melange Celebrates 37 Years1611 S Catalina Ave, Redondo BeachThe South Bay staple celebrates nearly four decades in business with a night of food, wine and stories. Hear tales from owners Michael Franks and chef Robert Bell while enjoying a meal. Call 310-540-1222 for reservations.COST: $95, plus tax and service; MORE INFO

TUESDAY, NOVEMBER 26Never Surrender: A Galaxy Quest DocumentaryVarious SoCal movie theatersThe meta sci-fi comedy starring Tim Allen, Sigourney Weaver, Alan Rickman and Sam Rockwell, gets more meta thanks to a documentary. Produced by Fandom and Screen Junkies, the doc features insight from the original cast along with commentary from Galaxy Quest director Dean Parisot, and Star Trek fan-favorites Wil Wheaton and Brent Spiner. The one-day only event also features deleted scenes and the premiere of the "Honest Trailer" for film, which was released 20 years ago.COST: Varies; MORE INFO

WEDNESDAY, NOVEMBER 27; 8 - 9 P.M.Thanksgiving Feast Show Upright Citizens Brigade Theatre 5919 Franklin Ave., Franklin VillageThis improv show recreates a family Thanksgiving meal with all its awkwardness and hilarity. From creepy uncles to troubled teens and out-of-it elders, watch this show to prepare yourself for the holidays. Since this is a "feast," audience members will be served food during the show.COST: $9; MORE INFO

WEDNESDAY, NOVEMBER 27 - SUNDAY, DECEMBER 29Love Actually LiveThe Wallis Annenberg Center for the Performing Arts 9390 N Santa Monica Blvd., Beverly HillsThe multimedia concert celebration of Richard Curtis's 2003 film returns to the Wallis after last year's smash run. Returning cast members Rex Smith, Carrie Manolakos, Doug Kreeger, Tomasina Abate, Carson Higgins and Emily Lopez join new players including Rogelio Douglas Jr., Declan Bennett, Jon Robert Hall and Chris Mann.COST: $39 - 125 ; MORE INFO

WEDNESDAY, NOVEMBER 27Truffle DayEataly L.A. 10250 Santa Monica Blvd., Century CityIn Italy and around the world, white truffles are a rare delicacy. For one day, Eataly offers the truffles at the lowest price in year, $4.90 per gram (that's up to 55% off) and just in time for Thanksgiving dinner.COST: Varies; MORE INFO

WEDNESDAY, NOVEMBER 27; 7:30 - 9:30 P.M.Planes, Trains and AutomobilesAero Theatre 1328 Montana Ave., Santa MonicaAvoid the freeways and duck into a screening of John Hughes's 1987 Thanksgiving-themed film starring Steve Martin and the late John Candy. When a stiff businessman meets an freewheelng fellow passenger, they're forced to travel together to make it to their homes in time for the holiday.COST: $12; MORE INFO

THURSDAY, NOVEMBER 28; 6 A.M. - 12 P.M.Turkey Trot Los AngelesLos Angeles City Hall 200 N. Spring St., downtown L.A.The 7th annual run returns with the goal of raising $50,000 for the Midnight Mission. Runners dressed in Thanksgiving costumes jog through DTLA's streets in a loop that starts and ends at City Hall. Participants are encouraged to donate money or bring blankets and towels. The events begin at 6:45 a.m. and end after the Widdle Wobble fun run for kids at 10:15 am. Registration includes a Turkey Trot L.A. T-Shirt and a finisher medal. COST: $20 - $70; MORE INFO

Looking for other options? There are tons of Turkey Trots happening around Southern California. Here are a few.

If you're hosting guests this week, or not going anywhere for the holiday, you've got options.

Through SUNDAY, DECEMBER 1The Thanksgiving PlayGeffen Playhouse 10886 Le Conte Ave., WestwoodWritten by Larissa FastHorse (What Would Crazy Horse Do?, Landless) and directed by Michael John Garcs (Urban Rez, The Royale), the play asks how do you celebrate Thanksgiving and Native American Heritage month at the same time? The satire follows "three 'woke' white thespians tasked with devising an elementary school pageant about the first Thanksgiving." The production pokes fun at political correctness and the politics of entertainment?COST: $30 - $120; MORE INFO

Through SUNDAY, JANUARY 12 Moonlight ForestLos Angeles County Arboretum 301 N. Baldwin Ave., ArcadiaThe lantern art festival features interactive displays and two new themes, Polar Dreams ,which features penguins and cuddly sled dogs, and Ocean Visions, which features exotic fish, giant sharks and undersea creatures. COST: $23 - $28; MORE INFO

Through TUESDAY, DECEMBER 10Key LargoGeffen Playhouse Theater 10886 Le Conte Ave., WestwoodDanny Pino, Andy Garcia and Joely Fisher star in Maxwell Anderson's Broadway play (made famous by the pairing of Humphrey Bogart and Lauren Bacall in the film noir). Returning from World War II, disillusioned vet Frank McCloud (Pino) travels to a hotel in Key Largo to pay his respects to the widow of a fallen friend. But now has to deal with the mobsters, led by the ruthless Johnny Rocco (Garcia), who have taken over the joint. COST: $30 - $155; MORE INFO

Through SUNDAY, JANUARY 5; 6 - 10 P.M.L.A. Zoo LightsLos Angeles Zoo 5333 Zoo Dr., Griffith ParkThe holiday season begins at the zoo with the return of its fantastical light display. The self-guided, 60 to 90 minute walk features wildlife-inspired displays, lights, projections and immersive interactive experiences.Treats and visits with Santa are also available.COST: $11.95 - $21.95; MORE INFO

Through SUNDAY, DECEMBER 29JitneyMark Taper Forum 135 N. Grand Ave., downtown L.A.Tony Award-winner Ruben Santiago-Hudson directs the Center Theatre Group's presentation of August Wilson's classic. Set in the 1970s, the play follows a group of men who drive unlicensed cabs aka jitneys. When the city threatens to board up the business and the boss's son returns from prison, tempers flare and secrets are revealed.COST: $25 - $125 ; MORE INFO

Through SUNDAY, DECEMBER 1Los Angeles Auto ShowConvention Center 1201 S Figueroa St., downtown L.A.Car enthusiasts can check out more than 1,000 vehicles including debuts, custom and exotic cars, test drives and activations for drivers and non-drivers alike. The show hosts its first-ever LEGO booth, which honors SoCal's car culture and also features a life-size LEGO Bugatti Chiron.COST: $6 - $35 admission; MORE INFO

Through SUNDAY, JANUARY 5Enchanted Forest of LightDescanso Gardens 1418 Descanso Dr., La Caada FlintridgeTake a one-mile nighttime stroll through the garden's foliage, which will be illuminated with interactive installations that allow guests to manipulate the lights and sounds. Tickets are timed and are rain-or-shine.COST: General admission tickets start at $28; MORE INFO

FRIDAY, NOVEMBER 22 - SUNDAY, JANUARY 5Santa's Village - A Nostalgic Christmas in the WoodsSkyPark at Santa's Village 28950 California 18, SkyforestThe outdoor adventure park near Lake Arrowhead plays host to Santa throughout the holiday season. There are activities and entertainment for all ages such as meet-and-greets with Mr. Claus, magic show, ice skating, parades and light shows. Day passes also include access to park attractions like ziplining, an archery range, an ax challenge and pedal cars.COST: $49 - $59; MORE INFO

Through SATURDAY, JANUARY 4Magic Lantern FestivalPomona Fairplex 1101 W. McKinley Ave., PomonaEvery Saturday through Jan. 4, the Chinese Lantern Festival returns for the holiday season. View illuminated displays with the theme "Blooming Seasons." Bask in the glow of lanterns strung up to 30 feet high and a 100-yard-long ceramic dragon. You'll also learn about the art of lantern-making in China, which dates back 2,000 years.COST: $15.50 - $27; MORE INFO

Through SUNDAY, DECEMBER 2229th Annual Winter FantasySawdust Art Festival 935 Laguna Canyon Rd., Laguna BeachWhile most people visit the Sawdust Festival grounds during the summer, the three-acre art village transforms into a snowy wonderland for five weekends during the winter. The festival features 180 artists and makers, three stages of music, art demonstrations, a petting zoo, holiday lights, trees and Santa. The community tree lighting takes place on Saturday at 5:30 p.m. COST: $4 - $12, and active or retired members of the military, and three members of their family get in for free.; MORE INFO

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31 Fabulous Things To Do In Southern California This Thanksgiving Week: Nov. 25-28 - LAist

Town Cuts Tree Lighting From Holiday Celebration To Appease Those ‘Offended’ By The Tradition – The MIX

The town of Durham, New Hampshire finally submitted to the politically correct police this year by agreeing to remove the tree lighting from their annual holiday celebration. The decision was announced after the town received complaints about the tree lighting tradition.

CBS reported that the event which was previously known as the Annual Tree Lighting Ceremony will now be called Frost Fest. And the tree lighting at the center of the celebration will no longer be part of it.

While Santa will attend the event, he will not be in a town firetruck as he has in the past. In addition, the wreaths that traditionally adorned lamp posts on Main Street will not be put up this year.

Town Council member Sally Tobias explained that these changes were made after someone complained that they are offended by the Christmas themes in the ceremony.

There was another private citizen that came forward and said that he had always had a problem with the Christmas tree, as he called it, Tobias said.

After a public meeting held by town officials, aworking committee was formed that went about making changes to the event.

There were a couple of people that did express some concerns about how they felt being included, Tobias said.

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Rabbi Berel Slavaticki of the University of New Hampshire and Seacoast Chabad Jewish Center praised the town for not doing the tree lighting this year, saying the Town Council is moving in the right direction.

To stop cultures and faiths from practicing publicly would be very un-American. I think thats the beauty of our country, the Rabbi said.

He added that last year, he had asked the town to display a Menorah during the eight days of Hanukkah, but his request was denied.

The Supreme Court ruled in 1989 that the Menorah and the Christmas tree both represent the holiday winter season, Slavaticki said.

Tobias herself admitted that she is not a huge fan of the changes that have been made, but she added that the town is open to feedback from others.

I will state that trees and Santas and wreaths are not Christian, Tobias said, And we would like to hear back from the community. Wed like to hear what they think about it, how they would like to see it evolve a little differently and how we can make it better.

This isnt the first time Durhams Annual Tree Lighting Ceremony has been at the center of controversy. Last year the Human Rights Council pressured the town to discontinue the tree lighting. This year, it would seem the Council finally caved.

Read the story: Town Fights Back Against Ban on Christmas Tree Lighting

Why is it that liberals who are obsessed with political correctness feel the need to ruin absolutely everything that is good and fun in the world?

What happened in Durham shows once again that there really is a war on Christmas, and that liberals will not be satisfied until all signs of the Christian holiday are erased forever.

We can only hope that town officials come to their senses and reinstate the annual tree lighting ceremony.

Its a shame that the entire town is going to be deprived of this Christmas event just because of a few Scrooges.

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Town Cuts Tree Lighting From Holiday Celebration To Appease Those 'Offended' By The Tradition - The MIX

The smashing and killing is ramped up a notch in War of the Worlds episode 2 – review – The Independent

A baffling amount of attention has been paid to the supposed wokeness of the BBCs adaptation ofTheWar of the Worlds. Several national publications have joked that it has all gone woke in Woking the Surrey town in which HG Wells1898 disaster novel, and this new three-part series, is set. The reason? One of the characters is female, and another vaguely hints at being gay. We must alert the church elders.

In last weeks first episode of this intriguing, if hardly pacy, adaptation, protagonist Georges biggest problem was that his ex-wife/cousin was refusing to divorce him, and thus he couldnt marry his new girlfriend Amy (Eleanor Tomlinson, sharing just enough chemistry with Rafe Spalls George to sell the relationship, but no more). Until, that is, a strange meteor crash landed in their sleepy village, cracked open, and revealed an arachnoid machine that proceeded to murder everyone in its path. The invaders, it was deduced, had come from Mars.

Sharing the full story, not just the headlines

The second episode begins a few years on. Amy is searching in vain for her lost partner, their son George Jr in tow. Gone is the lush greenery, the quaint villages and the smog-filled London cityscape. In its place is a vast, Tatooine-like desert bathed in red light. The Martians seem to be dead, killed shortly after arrival, but the chaos they unleashed remains. Food is scarce. Instead of crops, red glassy shards jut out of the ground. The survivors dont sing God Save the King, but God Save Us All. It is a bleak state of affairs. Well, as far as I can make out, squinting at the screen, it is. The BBC has a frustrating habit of hiding its action in the shadows, as if darkness equals drama.

Its generally accepted that Wellsnovel, about the invasion of Earth by Martians, is an allegory though for what, nobody can quite agree. Is it a prescient environmentalist warning? A fable about the hubris of humanity? A critique of imperialism? Im surprised that in all the scandalised chatter about political correctness, nobody has questioned the timing of reviving a story such as this: a foreign species arrives in Great Britain and destroys the natural order of things. It seems that something has arrived in England, announces Nicholas Le Prevosts Chamberlain. It has completely destroyed Weybridge railway station and massacred an entire battalion. Another character declares: Unless we think of some way to stop this, this will not be our planet anymore. Is this not uncomfortably evocative of xenophobic Brexit rhetoric? Hey ho. Maybe I should just enjoy the smashing and killing.

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As a slightly cheesy reminder of what we love about Doctor Who i.e. the fact it gives us an intergalactic eccentric in a big flappy overcoat shouting at Daleks this is a New Year treat that more than delivers

BBC

Billy Connolly: Made in Scotland is a meandering look back over his life, career, and national identity a Proustian wander through Scotland. Theres a lot of mordant chat about the weather, illustrated with shots of dark grey clouds above even darker grey lochs.

BBC/7Wonder/Jaimie Gramston

From the outset the production is elevated by its sensitive handling of the men and the Paratroopers remain exclusively male involved. These kinds of programmes have a tendency to fetishise toughness, lingering on assault courses and weaponry.

Jonny Ashton/ITV

Despite what some feared, the casting of Cumberbatch doesnt simply flatter Cummings the A-lister is too good a chameleon for that. But, inevitably, as he scrawls out his campaigning brainwaves on a whiteboard, there is a touch of that deductive maverick Sherlock in his portrayal of this scruffy, balding political saboteur.

Nick Wall

The programme-makers must have done much to win the confidence of so many friends and families, as they went through unspeakable personal pain; but they repay that confidence with an understated and powerful film.

Channel 4

This documentary goes behind the shrubbery to show off these animals and their guardians. The humans are a pretty exotic bunch too, judging by some of the lines they come out with.

Channel 4

You see, saint or sinner, prince or pauper, we are all part of one race, the brotherhood of man. And the saintly and regal Danny Dyer stands as its finest ambassador.

BBC

West believes Valjean to be the greatest hero in all literature, and he plays the part with all the care and intricacy such a character deserves.

BBC/Lookout Point/Laurence Cendrowicz

For anyone whos not altogether sure how British politics turned so suddenly into a rolling dumpster fire from which all exits are blocked then Inside Europe: Ten Years of Turmoil is a necessary public service to explain exactly, and exactly how needlessly, we all came to be here.

BBC/European Council Newsroom

Theres really been nothing quite like Catastrophe on our screens before, and it deserves its cult status for the quality of everything the production team do, not least the stunning cinematography in this finale. Thanks, all. Im glad Catastrophe died happy."

Channel 4

Yet again the Williams have woven a brilliantly tangled web, helped in no small part by Karyos quietly arresting central turn

PA

It is both a revisionist and frequently batty take on the caped milieu and a winningly knotty mystery. And it surely is the first big-budget superhero tale more indebted to Wes Anderson than to Stan Lee.

Netflix

Like all the best detective dramas, Shetland engages the audience in the very process of detection. That way we grow intrigued, and we care. And so we find ourselves sitting next to Henshall in his (prominently featured) Volvo V70 estate, sharing his thoughts, intercepting suspects and being driven off the road by unidentified enemies.

BBC/ITV Studios

"This Time with Alan Partridge is such a consistently strong creative achievement that fears for the future of Alan Gordon Partridge, may, once again, be allayed. Or Alayned, perhaps.

BBC

"Michael Jackson has long looked like a burning tire yard. There were the allegations, the out-of-court settlements, the arrest, the trial and not-guilty verdict. But there has been nothing like Leaving Neverland

AFP/Getty

"Home is a rather gentle, unobtrusive variation on the sitcom theme but one that is built on a quite a bizarre premise. The twist is that a family who returns to Surrey from a holiday touring around France discover a Syrian refugee stuffed in the back of their SUV. Not only that, but, after a few moments of blind terrified panic about a suicide bombing, they eventually adopt him like hes stray cat thats just wandered in."

Channel 4

"A tremendously sad, strange story then, and just as unfathomable today. Dandos friends, family and the producer and director of the film have made a fitting and balanced tribute to her, something she deserves. I cant really add anything to that."

PA

"It is sometimes remarked that the Troubles in Northern Ireland make for an unpromising backdrop for a sitcom about adolescent kids. Well, yer mans wrong, as they might say. Derry Girls, returning for a triumphant and exuberant second run, proves that humour, dark or otherwise, can be quarried from even the most unlikely of locations."

Peter Marley

"While there are plenty of well-turned one-liners, the deeper attraction of Fleabag is schadenfreude. The character is as old as Daisy Buchanan or Lydia Bennett or Scarlett OHara. The best compliment to Waller-Bridge and her cast is that they find fresh clothes in which to dress these ancient monsters."

BBC/Two Brothers/Luke Varley

"The Road to Brexit is easily the best thing to emerge from the whole brexit imbroglio. OK, not much competition, but still... Despite the po-faced title, you realise very quickly that its not yet another drama starring Benedict Cumberbatch or yet another attempt by Laura Kuenssberg to explain the inexplicable, or yet another show with the public arguing about stuff they dont understand. Rather, its a very clever, very funny, very 'different' parcel of bollocks to Brexit."

BBC

"The footage is glorious, especially the side-on tracking shots of the birds and the hunting, where it is as if the cameramen were able to set up a rail along the ocean. Most spectacular of all is the sequence of a glacier collapsing into the ocean, where 75m tons of ice being sloughed off in less than 20-minutes. But at times Our Planet feels a little unfocused. Attenboroughs last big BBC series, Dynasties, won almost unbearable amount of emotional resonance through its focus on animal families. Our Planet is more of a greatest-hits parade, with overblown orchestral soundtrack and ponderous intonation. You cant buy love, even if you pay for David Attenborough."

Netflix

"Plausibility is a spectrum; Bodyguard became ridiculous but Line of Duty stays just the right side, and as usual there is more plot in an hour than in whole series of other programmes. As well as being gripping entertainment, Line of Duty has become an effective examination of the relationship between the state and the individual. The shadowy government forces are elected; the organised crime gangs are fuelled by the drug trade. The police are there to save us from ourselves but can only do it if they are subjected to constant scrutiny. Its exhausting work, policing the police."

BBC

"Joseph is almost never out of shot, whether seen from afar, contemplating a bottle of strong cider in a playground, or in visceral close-up, clutching his doner to his face. There are few actors you could trust with so much screen time, especially with such a pared back and naturalistic script. The fact any of it is remotely watchable is testament to Stephen Grahams abilities. No man working in Britain today can drink a pint with more pathos."

Dean Rogers/Channel 4

'Good Omens is a hugely enjoyable, imaginative premiere, as close to Pratchetts vision as anyone could have dared dream. And while the melancholy tone may not be for everyone, fans of the book will surely be sated.'

Amazon Prime

"Years and Years, then, is favoured by some wit, a cornucopia of fab talent and promising characters. The dominant one as we continue our quest into the 2030s and beyond, will be Vivienne, or Viv, Rook, played brilliantly by Emma Thompson. As a bit of a long-term Emma-sceptic I was actually startled by how good she is in the role of the epitome of everything she has spent her life hating and campaigning against, for Viv is a horrifically nasty businessperson turned populist politician with the most terrifying of views. Viv Rook makes Ann Widdecombe look like, well, Emma Thompson at an Extinction Rebellion sit-in."

BBC

"As the series develops, its clearer than ever that Eve and Villanelle are more similar than they are different. Villanelles new vulnerability invites us to question what it is exactly she wants from Polastri. First time around she was toying with a more worthy adversary, but why now? Polastri, by contrast, is frayed around the edges, a terrible wife to her husband Nico (Owen McDonnell) and an even worse intelligence agent to her boss Carolyn Martens (Fiona Shaw). The script is still tight and the jokes are still there, as are Villanelles accents, outfits and abrupt killings, but without the will-they/wont-they energy of the initial plot, it is harder to care."

BBC/BBC America

"Timely, bleak, intelligent and compelling, Chernobyl is a triumph of a disaster."

HBO

"Season three's knuckle-whitening finale is far less disappointing than the last."

Hulu

"The writing is sharp and well observed, probing the fault lines between small talk and real problems."

Channel 4

"A touching tribute to a flawed reality TV star."

Channel 4

"Despite the strength of its ensemble cast, Succession is a feat of writing above all. Although it is ostensibly a business show, you wont learn much about the minutiae of media deals by watching it. Its key dynamic, between father and children, means that it is limited in the amount that can actually happen without risking the magic. The writers, led by the creator Jesse Armstrong, who also gave us Peep Show, weave just-about-plausible and sympathetic characters from a web of insults and backstabbing, and tight editing and camerawork ratchets up tension from a slow-moving plot."

HBO

"In Kathy Burkes All Women on Channel 4, the unapologetic, effing-and-blinding, salt-of-the-earth actor meets lots of different women from nuns to reality stars to understand what it means to be a member of the fairer sex, so to speak, in 2019."

Channel 4

"So here we have an intriguing, but rather flawed sort of Big Brother thriller set in our contemporary world of digital snooping, near constant surveillance and (a topical touch) widespread use of facial recognition technology."

BBC/Heyday Films/Nick Wall

"Top Boy can be bleak and violent, with dialogue so naturalistic that it verges on the impenetrable, but in telling stories that rarely get heard, it asks us to think differently about the city we live in."

Netflix

"Criminal uses its small canvas to ask big questions. The focus on these intricate dances means that after a while we begin to question the idea of objective truth, as well as the facts at hand. I have no idea if it is a realistic depiction of detective work, but it makes for gripping drama."

Netflix

"After an hour of Tories at War (Channel 4), I felt I had to get out into the fresh air and go for a walk. The foul language; the visceral hatred; the unbearable tensions; the violence being inflicted on ancient institutions and this poor old knackered country by the Tories, as if with chainsaws and zombie knives it was like watching my first Saw movie."

Pro Co

"In a TV world where too often we are encouraged to see the Nazis as warm and cuddly real people with emotions, its refreshing that they are here relegated back to pure baddies, strafing cafes, shooting surrendering fathers and generally being Nazi-ish about things."

BBC/Mammoth Screen

"At last, an answer to the question, what could be more fabulous than Helen Mirren playing The Queen? Helen Mirren playing an empress, altogether madder, badder and more dangerous to shag. Better costumes, too."

Sky Atlantic

"Sarah Phelpss adaptation of crime writer Tana Frenchs novels finds two detectives trying to solve the murder of a young girl, with plenty of twists and turns."

BBC

"Romance is complicated, cathartic and messy, regardless of age or circumstance. But such uncomfortable realities are swept beneath the rug in John Carneys rigorously whimsical new Amazon series. Modern Love is adapted from a New York Times column (it also spawned a hit podcast) and is as much a valentine to a fantasia vision of Manhattan as it is a dissection of the human heart."

Amazon Studios

"Damon Lindelofs version of the beloved graphic novel is a compelling demonstration of what can happen when source material is treated with sensitivity and imagination."

HBO

"Arriving in the wake of Marvels Black Panther, the film highlights the links between the saga of the real-life Agoji women, who fought in the former Kingdom of Dahomey (located in modern-day Benin), and the all-women comic-book world protectors known as Dora Milaje."

Channel 4

"The writer Jack Thorne says his latest four-part drama, which explores the aftermath of a disaster on a small community, was shaped by the Grenfell Tower fire. Rather than overcrowded west London, his takes place in Glyngolau, a fictional run-down town in Wales. A new building project, The Light, is being built on the outskirts. Its unclear what The Light is, exactly, which is deliberate. The point is not what it is, exactly, but what it represents: 1,000 new jobs and a rare moment of economic optimism for families who have forgotten what hope feels like."

Channel 4/ Warren Orchard

"Watching Seven Worlds, One Planet, its hard to know what to worry about most: the future of wildlife catastrophically imperilled by our fondness for fossil fuels, long-haul travel and convenience food or Attenborough himself, now 93 and one of the few people that the world will listen to about the impending apocalypse. Like the species on whose behalf he speaks, his continued existence is vital for us all."

PA

"Hailee Steinfeld is perfectly cast. She has a face and a set of elastic expressions that feels both well-suited to a period piece (as first displayed in her Oscar-nominated role in True Grit in 2010), and resolutely out of place in it. Just as Emily Dickinson was. Steinfeld crackles with charm and impropriety."

Apple/Virginia McMillian

This is a beautiful, brooding vision of Pullmans universe, which retains the mix of childish wonder and darkness that make his books so beguiling to young adults.

BBC/Bad Wolf/HBO

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As a slightly cheesy reminder of what we love about Doctor Who i.e. the fact it gives us an intergalactic eccentric in a big flappy overcoat shouting at Daleks this is a New Year treat that more than delivers

See the original post here:

The smashing and killing is ramped up a notch in War of the Worlds episode 2 - review - The Independent