PUBLIC RELEASE DATE:

13-Jun-2014

Contact: Peter Kent pkent@clemson.edu 864-723-0491 Clemson University

GREENWOOD, S.C. Seven research projects from Greenwood Genetic Center and Clemson University faculty were selected to receive the first round of funding provided by Self Regional Healthcare (SRHC).

In February, SRHC announced a partnership with Clemson and GGC to serve as the lead hospital partner in the collaborative. As part of that commitment, the hospital pledged a total of $5.6 million toward the project, including $1.2 million per year for three years to fund genetic research.

Fourteen projects were submitted from faculty at both Greenwood Genetic Center and Clemson University. Each project was evaluated by an independent team, and final selections were announced this week by Dr. Steve Skinner, director of the Greenwood Genetic Center, and Steve Kresovich, the Robert and Lois Coker Trustees Chair of Genetics/SmartState Chair of Genomics at Clemson.

Five of the funded projects focus on the understanding and treatment of autism spectrum disorders, while two proposals were combined to study improved diagnostics for hereditary cancers.

"The blending of research teams from both Clemson and GGC will allow our institutions to build on the strengths of one another," said Skinner. "Self Regional's commitment to supporting these endeavors is a vital part of understanding, and ultimately treating, disorders like autism and cancer that impact so many families."

Each selected project includes team members from both Clemson and Greenwood Genetic Center. The following proposals were funded:

Modi Wetzler from Clemson's department of chemistry will work on developing a therapy for autism patients who have a specific known mutation.

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Clemson, Greenwood Genetic Center research into autism, cancer funded by Self Healthcare

PUBLIC RELEASE DATE:

11-Jun-2014

Contact: Bill Schappert bschappert@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle, NY, June 11, 2014Men who have sex with men (MSM) account for more than 60% of HIV infections in the U.S. and 78% of new infections in men. Antiretroviral therapy can control HIV infection and suppress viral load, but mental health and substance abuse problems common among MSM can interfere with medication adherence. How conditions such as depression and alcohol and drug abuse can affect anti-HIV therapy and the success of various interventions are explored in an article published in LGBT Health, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the LGBT Health website.

Jaclyn White, MPH, Janna Gordon, and Matthew Mimiaga, ScD, MPH, Fenway Health, Massachusetts General Hospital/Harvard Medical School, and Harvard School of Public Health, Boston, MA, review the mental health problems and specific substances that pose the greatest threat to medication adherence among MSM. Targeted interventions can improve MSM's psychosocial problems while also helping them adhere to their antiretroviral drug regimens. Effective strategies identified through rigorous clinical trials must be translated into clinical practice, suggest the authors in the article "The Role of Substance Use and Mental Health Problems in Medication Adherence among HIV-Infected MSM."

"For people living with HIV, the importance of adherence to antiretroviral therapy cannot be over-emphasized," says Editor-in-Chief William Byne, MD, PhD, Icahn School of Medicine at Mount Sinai, New York, NY. "It is essential to preventing both the manifestations of infection in the individual and the sexual transmission of the virus to others. In this article, White and colleagues show the importance of addressing mental health and substance use in antiretroviral adherence interventions for MSM."

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About the Journal

Spanning a broad array of disciplines LGBT Health, published quarterly online with Open Access options and in print, brings together the LGBT research, health care, and advocacy communities to address current challenges and improve the health, well-being, and clinical outcomes of LGBT persons. The Journal publishes original research, review articles, clinical reports, case studies, legal and policy perspectives, and much more. Complete tables of content and a sample issue may be viewed on the LGBT Health website.

About the Publisher

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Harvard study finds substance abuse & mental health problems in MSM interfere with HIV medication adherence