High Unmet Needs in Therapeutics to Spur Growth in the Market for Nanotechnology in Drug Delivery, According to New …

San Jose, California (PRWEB) January 20, 2014

Follow us on LinkedIn Pharmaceutical industry represents one of the early beneficiaries of advancements in nanotechnology. Nanotechnology holds the potential to dramatically alter the fields of drug delivery, drug discovery, in vivo imaging, in vitro diagnostics, tissue engineering and implants. Of all the areas of nanomedicine, drug delivery remains the most researched and commercialized areas for nanotechnology in medicine. Nanoscale delivery systems hold potential to reduce undesirable effects of medication while improving therapeutic efficacy. Advancements in this area is expected to result in re-investigation of molecules whose development was earlier shelved due to lower pharmaceutical activity but were known to be biologically active. Also, nanoscale delivery systems can help improve efficacy of certain drugs that are already on the market.

Business interests in the application of nanotechnology is fast rising, driven by rising intensity in research work in this area and growing competition within the general drug delivery technologies. The pharmaceutical industry is witnessing increasing demand for novel drug delivery technologies, as companies seek to minimize drug side effects, reduce quantity of costly active therapeutic agents, and endeavor to differentiate their products from competition as well as from commoditization. In this regard, nano-milled/nano-sized/nano-crystallized products and nanocarriers, such as liposomes, among other approaches are providing a new set of tools to address these issues. Nanomaterials provide novel functions and features that are not delivered by other drug delivery technologies. In addition to enhancing therapeutic efficacy and improving safety profile of existing drugs, nanotechnology has the potential to deliver an all important means of developing next generation drugs. The ability of dendrimers and micelles to act as imaging agents as well as therapeutic agents is a significant progress in this direction, assisting clinicians in imaging as well as treating tumors.

Nanotechnology-based drug delivery is being seen as a revolution in protein and gene therapy, for delivering biomolecules such as DNA and siRNA, enabling researchers to overcome several hurdles that are found in these therapies using conventional delivery systems. Given the harm caused by chemotherapeutic agents to healthy tissues alongside diseased cells, there is growing interest and efforts to deliver anti-cancer agents directly to tumors, using nanotechnology based delivery systems. In addition, efforts are underway to develop oral formulations of various therapeutic agents. While several drugs delivered orally breakdown in the stomach, nanotechnology-based drug delivery is being explored to ensure smooth passage of a medication through the stomach such that they enter the intestines and are absorbed by the intestinal walls and passed on to the blood stream.

As stated by the new market research report on Nanotechnology in Drug Delivery, the United States represents the largest market worldwide. Growth in the country is driven by various factors such as a strong pharmaceutical industry with robust expertise in related sciences, high focus on R&D, and narrowing drug pipelines of major pharmaceutical companies, among others. Asia-Pacific led by China is forecast to grow at the fastest CAGR of 70% over the analysis period. China is making rapid strides in the area of healthcare and pharmaceuticals. In recent years, the country has made healthcare improvement a domestic priority, with a special focus on introducing advanced medical technology. Nanocrystals dominate the market worldwide, supported by shorter development time and lower cost of production. Nanocarriers, such as liposomes, dendrimers and micelles are expected to witness strong growth in the coming years.

Major players covered in the report include Access Pharmaceuticals Inc., Alkermes PLC, Aquanova AG, Camurus AB, Capsulution Pharma AG, Celgene Inc., Flamel Technologies SA, Lena Nanoceutics Ltd., NanoBio Corporation, and NanoCarrier Co. Ltd., among others.

The research report titled Nanotechnology in Drug Delivery: A Global Strategic Business Report announced by Global Industry Analysts Inc., provides a comprehensive review of market trends, drivers, challenges and strategic industry activities of major companies worldwide. The report provides market estimates and projections in US dollars for all major geographic markets including the United States, Canada, Japan, Europe (France, Germany, Italy, UK, Spain, Russia and Rest of Europe), Asia-Pacific, Latin America and Rest of World. Product segments analyzed for the global market include Nanocrystals and Nanocarriers.

For more details about this comprehensive market research report, please visit http://www.strategyr.com/Nanotechnology_in_Drug_Delivery_Market_Report.asp

About Global Industry Analysts, Inc. Global Industry Analysts, Inc., (GIA) is a leading publisher of off-the-shelf market research. Founded in 1987, the company currently employs over 800 people worldwide. Annually, GIA publishes more than 1300 full-scale research reports and analyzes 40,000+ market and technology trends while monitoring more than 126,000 Companies worldwide. Serving over 9500 clients in 27 countries, GIA is recognized today, as one of the world's largest and reputed market research firms.

Global Industry Analysts, Inc. Telephone: 408-528-9966 Fax: 408-528-9977 Email: press(at)StrategyR(dot)com Web Site: http://www.StrategyR.com/

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High Unmet Needs in Therapeutics to Spur Growth in the Market for Nanotechnology in Drug Delivery, According to New ...

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(WFLA) When Judy Loar, 68, could not bear to walk any longer due to excruciating pain in both of her knees from degenerative joint disease, she did what most people in her condition do, she went in for a surgical knee replacement.

After being released, Loar found out her knee cap had been set incorrectly.

Going through surgery again to fix her other knee was not an option, so Loar started researching other alternatives to ease the agony of bone-on-bone friction caused by her condition.

"I really did my research, because I knew I could go through another major surgery," said Loar who became a patient of Dr. Dennis Lox.

Dr. Lox is the founder and medical director of Tampa-based Florida Spine and Sports Medicine Center, and one of the world's leading doctors specializing in using stem cell therapy as an alternative to successfully treat debilitating injuries or conditions.

Loar describes the procedure as painless, with no down time.

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The Practicing Parent: Pros & cons of stem cell banking

Umbilical cord stem cell banking can be expensive and controversial, but Jamie and Ben Page decided to bank their daughter, Harlow's stem cells just in case.

"We had heard about cord blood banking and talked about it a lot and thought let's just go for it and have it just as a backup," Jamie Page said.

They did need it. Harlow had cancer in her uterus.

"On the ultrasound they immediately saw that there was a mass in her abdomen about the size of a grapefruit," Page said.

After a year of chemo, the tumor was gone. Doctors wanted to keep it that way.

"So, when the doctors found out we actually had her own stem cells, they were very excited," Page said.

Oncologist Elaine Morgan says those stem cells helped Harlow.

"I think that her umbilical cord cells were used as a boost to her own cells when we harvested her to have adequate cells for reconstitution," Dr. Morgan said.

Dr. Morgan does not advocate private cord stem cell banking at birth to be saved for a healthy baby's later use, because it's not clinically useful and it's expensive.

The Pages paid almost $2,000 for the initial banking fee, plus an extra $125 per year.

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The Practicing Parent: Pros & cons of stem cell banking

Matt Wallaert, Behavioral Scientist for Bing Skypes with Westwood Students – Video


Matt Wallaert, Behavioral Scientist for Bing Skypes with Westwood Students
Matt Walleart Skypes with the 2nd period Intro to Computer Science class with teacher Vicki Davis @coolcatteacher and her students. They talk about behavior ...

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Matt Wallaert, Behavioral Scientist for Bing Skypes with Westwood Students - Video

Comets – Crystalinks

Comets

A comet is basically a ball of ice and dust that looks like a star with a tail. Some comets do not have tails, looking like hazy, round spots of light.

A comet is a small body in the solar system that orbits the Sun and (at least occasionally) exhibits a coma (or atmosphere) and/or a tail - both primarily from the effects of solar radiation upon the comet's nucleus, which itself is a minor body composed of rock, dust, and ice. Comets' orbits are constantly changing: their origins are in the outer solar system, and they have a propensity to be highly affected (or perturbed) by relatively close approaches to the major planets.

Some comets are moved into sun grazing orbits that destroy the comets when they near the Sun, while others are thrown out of the solar system forever. A new comet may be discovered photographically using a wide-field telescope or visually with binoculars. However, even without access to optical equipment, it is still possible for the amateur astronomer to discover a sun grazing comet online.

Most comets are believed to originate in a cloud (the Oort cloud) at large distances from the Sun consisting of debris left over from the condensation of the solar nebula; the outer edges of such nebulae are cool enough that water exists in a solid (rather than gaseous) state. Asteroids originate via a different process, but very old comets which have lost all their volatile materials may come to resemble asteroids.

Historically, comets were thought to be unlucky, harbingers of destruction by anthropomorphic gods, or aliens, against humans. People are programmed to fear the unknown, but through scientific discovery, as with everything else along the way to enlightenment, there is always a physical explanation.

While hundreds of tiny comets pass through the inner solar system every year, very few are noticed by the general public. About every decade or so, a comet will become bright enough to be noticed by a casual observer - such comets are often designated Great Comets. In times past, bright comets often inspired panic and hysteria in the general population, being thought of as bad omens. More recently, during the passage of Halley's Comet in 1910, the Earth passed through the comet's tail, and erroneous newspaper reports inspired a fear that cyanogen in the tail might poison millions, while the appearance of Comet Hale-Bopp in 1997 triggered the mass suicide of the Heaven's Gate cult. To most people, however, a great comet is simply a beautiful spectacle.

Predicting whether a comet will become a great comet is notoriously difficult, as many factors may cause a comet's brightness to depart drastically from predictions. Broadly speaking, if a comet has a large and active nucleus, will pass close to the Sun, and is not obscured by the Sun as seen from the Earth when at its brightest, it will have a chance of becoming a great comet. However, Comet Kohoutek in 1973 fulfilled all the criteria and was expected to become spectacular, but failed to do so. Comet West, which appeared three years later, had much lower expectations (perhaps because scientists were much warier of glowing predictions after the Kohoutek fiasco), but became an extremely impressive comet.

The late 20th century saw a lengthy gap without the appearance of any great comets, followed by the arrival of two in quick succession - Comet Hyakutake in 1996, followed by Hale-Bopp, which reached maximum brightness in 1997 having been discovered two years earlier. The first great comet of the 21st century was Comet McNaught, which became visible to naked eye observers in January 2007. It was the brightest in over 40 years.

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Comets - Crystalinks

Comets end slide

January 19, 2014 - American Hockey League (AHL) Utica Comets The Utica Comets finally made their way back to the win column as they ended a six game losing streak with a 3-1 victory over the Hamilton Bulldogs. With the win, Utica claimed the season series from Hamilton, with five points over the quartet of games, as opposed to four points for the Bulldogs.

Joe Cannata bounced back in a big way after a rough two game stretch with 32 saves on 33 shots, en route to a first star nomination. Benn Ferriero scored twice for the Comets, while Pascal Pelletier netted assists on all three Utica goals. Winger Alexandre Grenier also scored for Utica, which moved to 12-20-2-3 on the season.

Ferriero got Utica on the board first, as he redirected a shot home to open the scoring. Peter Andersson's wrist shot from the point found its way through heavy traffic, off Pascal Pelletier's stick and onto Ferriero's stick, which jolted past Dustin Tokarski to make it 1-0 Comets. Ferriero's goal extended his point streak to five games.

The Comets doubled their margin 13:43 into the first as Grenier tipped a rocket of a slapshot from Henrik Tommernes past Tokarski, for the games only power-play goal. Pascal Pelletier and Henrik Tommernes picked up points for the Comets, which extended Ferriero's point streak to five games. Grenier leads all Utica skaters with three goals against their divisional rivals this season.

Hamilton peppered Cannata with 12 shots during the middle stanza, but was only able to beat the Wakefield, MA native once, as Maxime Macenauer scored 2:07 into the period. The Bulldog winger came straight out of the penalty box and found himself in alone on Cannata shorthanded and finished shortside to cut the Utica lead in half.

A tightly contested third period went back and forth with few whistles for much of the frame. With Tokarski on the bench, winger Benn Ferriero found loads of open ice off of a pass from Pelletier and buried it into the gaping net to ice the game. Brandon DeFazio also picked up an assist on the play.

With the victory, the Comets once again move into a tie with the Hartford Wolf Pack in an effort to get out of the league's basement. Both teams now sit with 29 points. Cannata earned his fourth victory of the season and moved to 1-0-0-1 against Hamilton. Ferriero finished as the leading scorer during the four game series between Utica and Hamilton, as his two goals gave him a total of seven points (2-5-7).

The Comets have two days off, before they return to the ice on Tuesday with the Chicago Wolves coming to the Mohawk Valley for the first ever meeting between the two teams. Puck drop is set for 7:00 p.m.

Tuesday is both College Night and Winning Tuesday at The AUD! College students can get a $12 dollar ticket with a valid student ID and fans can enjoy beer specials at all concession stands. If the Comets defeat the Wolves, all fans in attendance will also receive a free ticket to the following Tuesday's game against Lake Erie.

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L.A. Times Travel Show: 5 travel tips for music festival fans

Music insiders offered insights and travel tips about the world of music festivals at a Saturday panel at the L.A. Times Travel Show called "On the Road: Traveling for Music & Festivals." The panel returns noon Sunday.

Times staff writer Jessica Gelt led the discussion with Betto Arcos, host of KPFKs Global Village; Rick Farman, creator of the Bonnaroo Music and Arts Festival and Outside Lands; and Nigel Dick, filmmaker.

Secrets to tickets

If tickets sell out quickly, Farman recommended companies that sell packages, noting most are VIP packages. Bottom line: Be prepared to spend more if you really want in to a particular festival.

If you miss out on buying tickets to the multi-day Glastonbury Festival of Contemporary Performing Arts in England or other big festivals, Nigel Dick suggests checking out smaller festivals in Europe, even if there are no big acts. It's still a chance to have a cool cultural experience.

Navigating a festival

Do not get overwhelmed by all there is to see and do. "Festivals are not programmed for people to see everything. Theyre for people to have lots of different experiences, Farman said.

Arcos said to spend some time looking at the program, highlight those shows you have to see and then if you feel youve seen enough you can leave and go see another act.

Farman recommends that you budget more than half of your time for just wandering around. That is how you learn about new artists and acts, he said.

Split time between city and festival

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L.A. Times Travel Show: 5 travel tips for music festival fans