Research and Markets: Gene Therapy – Technologies, Markets and Companies – Updated 2013 Report with 180 Company Profiles

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/g2hdqj/gene_therapy) has announced the addition of Jain PharmaBiotech's new report "Gene Therapy - Technologies, Markets and Companies" to their offering.

Gene therapy can be broadly defined as the transfer of defined genetic material to specific target cells of a patient for the ultimate purpose of preventing or altering a particular disease state. Genes and DNA are now being introduced without the use of vectors and various techniques are being used to modify the function of genes in vivo without gene transfer. If one adds to this the cell therapy particularly with use of genetically modified cells, the scope of gene therapy becomes much broader. Gene therapy can now combined with antisense techniques such as RNA interference (RNAi), further increasing the therapeutic applications. This report takes broad overview of gene therapy and is the most up-to-date presentation from the author on this topic built-up from a series of gene therapy report written by him during the past decade including a textbook of gene therapy and a book on gene therapy companies. This report describes the setbacks of gene therapy and renewed interest in the topic

Profiles of 180 companies involved in developing gene therapy are presented along with 202 collaborations. There were only 44 companies involved in this area in 1995. In spite of some failures and mergers, the number of companies has increased more than 4-fold within a decade. These companies have been followed up since they were the topic of a book on gene therapy companies by the author of this report. John Wiley & Sons published the book in 2000 and from 2001 to 2003, updated versions of these companies (approximately 160 at mid-2003) were available on Wiley's web site. Since that free service was discontinued and the rights reverted to the author, this report remains the only authorized continuously updated version on gene therapy companies.

Benefits of this report

- Up-to-date on-stop information on gene therapy with 73 tables and 15 figures

- Evaluation of gene therapy technologies

- 740 selected references from the literature

- Estimates of gene therapy markets from 2012-2022

- Profiles of 180 companies involved and collaborations in this area

Originally posted here:

Research and Markets: Gene Therapy - Technologies, Markets and Companies - Updated 2013 Report with 180 Company Profiles

Think with Google Brazil: Travel. Futurist Speaker Gerd Leonhard (complete version) – Video


Think with Google Brazil: Travel. Futurist Speaker Gerd Leonhard (complete version)
you can find the entire video on my Vimeo channel here: http://vimeo.com/73312594 This is the video of my talk at http://thinkbrazil.withgoogle.com/travel/ag...

By: Gerd Leonhard

Excerpt from:

Think with Google Brazil: Travel. Futurist Speaker Gerd Leonhard (complete version) - Video

Freedom Hold off Late Rally and Sweep

September 1, 2013 - Frontier League (FL) Florence Freedom Washington,PA-The Florence Freedom built an early 5-0 lead and had to hold off a late rally by the Washington Wild Things for a 7-5 win Sunday night at Consol Energy Park.

The Freedom posted a five run second off Washington starter Dayne Quist(8-4). Pablo Bermudez and Aljay Davis produced back to back RBI singles. Kyle Bluestein also hit a three run homerun. It was Bluestein's third homerun of the year and his second on the six game road trip.

Rookie right hander Casey Henn(5-0) stayed undefeated as he pitched seven innings allowing six hits on three runs with a career high eight strikeouts. Two of the three runs he allowed were solo homeruns.

Henn had a no hitter through the first four innings. Stewart Ijames hit his fifteenth homer of the year against Henn in the fifth breaking up the no hitter and shutout. Scott Kalamar also added an RBI single in the inning making it 5-2.

Jim Jacquot doubled to right center in the sixth scoring Byron Wiley who also doubled extending the Freedom lead to 6-2. David Harris launched his fourteenth homer of the year in the eighth giving the Freedom a 7-2 lead.

Washington chipped away late in the game. Mario Mercedes homered off Henn to lead off the bottom of the eighth brining the score to 7-3.

In the bottom of the ninth, Mark Samuelson recorded an infield RBI single against Freedom reliever Jordan Conley cutting the deficit to 7-4.

After the Wild Things loaded the bases with one out, the Freedom called for closer Jorge Marban. He struck out Kalamar and then walked AJ Nunziato on a 3-2 pitch forcing home Samuelson making it 7-5.

Marban though buckled down though and struck out Nick Boggan to end the game. The Wild Things left the bases loaded. Marban registered his twenty sixth save of the season.

The Freedom completed a 5-1 road trip and still lead the final wild card spot with just three games left in the season.

Originally posted here:

Freedom Hold off Late Rally and Sweep

Freedom's Tanis Named League's MVP

September 1, 2013 - Frontier League (FL) Florence Freedom FLORENCE, KY - The Florence Freedom are pleased to announce third baseman Jacob Tanis has been named as the Frontier League's Most Valuable Player.

Tanis, 24, was elected the Morgan Burk Award winner as the MVP by managers, coaches, general managers and members of the league's media. Through 91 games this season, the Peachtree, Georgia native is fourth in the league with 17 home runs, and leads the league with 72 RBIs.

"We're so excited to honor Jacob as the MVP," Freedom manager Fran Riordan said. "He has been such a productive player for us both offensively and defensively. He's a great teammate and one of the most professional young men I've ever had the privilege to manage."

Tanis, in his first season with the Freedom, was also recognized on the league's post-season all-star team as the top third baseman. He wins these honors after not making the Frontier League's mid-season classic as an all-star.

"I think this speaks to how clutch he's been to our team down the stretch," Freedom General Manager Josh Anderson said. "He's proven that he's the guy you want at the plate when the chips are down."

The Freedom enter Sunday's action in Washington, Pennsylvania with a record of 51-41 and leading for the Frontier League's final wild card playoff spot by one game over the Gateway Grizzlies.

The Freedom are trying to make it back-to-back seasons with a post-season run. In 2012, the Freedom were league runners-up to the Southern Illinois Miners as the team fell 3-1 in the championship series.

Should Tanis and the Freedom clinch another playoff berth, the most likely scenario for the team to play it's first home game would be Tuesday, September 10 at 6:35pm at University of Cincinnati Medical Center Stadium.

The team will have the opportunity to clinch their playoff berth at home this week when the team returns home for it's final three regular season games Tuesday though Thursday against the Windy City Thunderbolts.

The Freedom are members of the independent professional Frontier League and play all home games at UCMC Stadium, located at 7950 Freedom Way in Florence, Kentucky. Playoff reserved ticket vouchers are currently on sale for only $8. The Freedom may be reached at 859-594-HITS (4487).

Read the original post:

Freedom's Tanis Named League's MVP

Freedom Park: Telling the real African story

Freedom Park: Telling the real African story

But this is not another apartheid museum. Nor is it the Hector Peterson Museum, or the Sharpville or Boipatong Monument. It is not Rhobben Island Museum, or the Kliptown Monument. It is much deeper. It goes back 3.6 billion years in history to tell an African story.//hapo attempts to tell an African story that has been distorted, suppressed and silenced. The story is divided into seven epochs.1.Earth - dealing with the creation of the universe. 2. Ancestors - exploring the concept of ancestors from physical to spiritual perspectives. 3. Peopling - showcasing Africa's pre-conquest societies from Timbuktu to Mapungubwe. 4. Resistance and Colonisation - recounting the major historical forces that gave birth to modern South Africa. 5. Industrialisation and Ubarnisation - dealing with exploration of minerals and its impacts on our lives. 6. Nationalisation and Struggle - stories from the tyrannical rule of colonisation and apartheid to a new South Africa.

Touring //hapo after a short welcome reception, which involves beating of drums and singing, and before a presentation on the first epoch, a quote from the opening of Thabo Mbeki's monumental speech, "I am an African," a speech which I think inspired Freedom Park, is plastered on the wall: "I owe my being to the hills and the valleys, the mountains and the glades, the rivers, the deserts, the trees, the flowers, the seas and the ever-changing seasons that define the face of our native land."

We are told that this speech actually informs all what //hapo is. I was there as a guest of South African Tourism, and I made a mental note to re-read the speech. We were then taken through the African story of creation of the universe. In the beginning, the story begins, there was uMvelingaqangi (the Creator). Then came the figure of uNomkhubulwane (the female water God). With uNomkhubulwane by his side, uMvelingaqangi became inspired and created first the rock, then fire, followed by water. Rock, fire and water mixed and crashed, and from the eruption was formed the endlessness universe. From the fire came the sun, and in a dark night sky, the moon and the stars. Earth came from the rock while water produced the oceans and the rivers. After Water and Earth, life began. Humans came later from the reeds and multiplied. There is no mention of Genesis or Adam and Eve in this account.

And this is how death came into being. uMvelingaqangi instructed the chameleon to send a message that the people would live on earth forever. But the chameleon stopped on the way to eat some berries and took long to arrive. This got the Creator angry. He then sent the lizard to tell people that they would instead die. The lithe lizard moved fast and delivered the message of death to the people before the chameleon, busy with berries, could reach the destination. It is said when chameleon finally arrived, people rejected his message of eternal life as they felt he had acted irresponsibly by putting personal appetite above duty. I am astonished that this story having been told to us innumerable times over, most people have stuck to the Bible version of death. I remember one outing with the boys in the bush when went on a killing spree of both chameleons and lizards after hearing this story.Said the curator of Freedom Park ,Sipho Mdanda: "We don't just state the previously distorted facts. //hapo is a living interpretive centre, one with which every South African will identify personally." But when we left //hapo for the next part of the park, my fascination was with its presentation of African (black) indigenous knowledge. There is a feeling that //hapo was meant to also crush the egos of those who claimed they were 'a superior God's chosen race'.

The next part is the Mveladzo, a Tshivenda word meaning spiral paths. The paths link all the park elements and are meant to take visitors on a "contemplative and painstaking hike symbolising the tough journey that South Africa went through". Visitors are then allowed rest at Uistpanplek, an Afrikaans word meaning resting place. The main memorial is named S'khumbuto (siSwati for memorial) and is a testimony to eight conflicts that have shaped the South Africa of today. These are Pre-Colonial Wars, Slavery, Genocide, Wars of Resistance, the South African War (formerly known as Anglo-Boer War), The First and the Second World War and the Struggle for Liberation. Skhumbuto comprises eight elements, each one with its own symbolism and meaning, namely, Wall of Names (with over 75,000 names of peopled that died in all South African conflicts), Amphitheatre, Sanctuary, Eternal Flame (that pays tribute to the unsung heroes and heroines who died without their names being recorded in history), Reeds, President's Tree (fittingly planted by Thabo Mbeki), Moshate (VIP suite) and Gallery of Leaders.

The Gallery of Leaders is said to showcase those leaders whose contributions stand out in human memory and history. It aims to inspire visitors to emulate the sacrificial and heroic lives of these commemorated leaders. The leaders that Freedom Park urges us to emulate as role models are Argentina's Che Guavara, Angola 's Argostinho Neto, Ghana's Kwame Nkurumah, Tanzania's Julius Nyerere and South Africans, O. R. Tambo, Robert Sobukwe, Steve Biko, Lillian Ngoyi and Helen Joseph, the latter two being the only women in the gallery.The fifth major element of Freedom Park is Isivivane (Nguni word for scared space). This is the spiritual resting place for those who played a part in the freedom and liberation of South Africa. Isivivane has four key components; Lesaka and its boulders, Lekgotla, water and trees called Umlahlankosi.

Prior to the opening of the park, cleansing and healing and Return of Spirits ceremonies were performed throughout the areas of conflict in South Africa and internationally. We hear that soil from these conflict areas was brought to Lesaka as part of laying the spirits to rest. Each of the nine South African provinces provided a boulder from a place of importance to construct Lesaka. These nine boulders plus two others representing South Africa's national government and the international community form the circular face of Lesaka.I removed my shoes, in accordance with the requirement for visitors who enter Isivivane to pay homage to thousands of 'my people' who perished in these conflicts. I circled around Lesaka touching each boulder and silently uttering salutations to the thousands of spirits resting here.And this is how we do it in Africa. Mbeki observed in 1996: "Today, as a country, we keep an audible silence about these ancestors of the generations that live, fearful to admit the horror of a former deed, seeking to obliterate from our memories a cruel occurrence which, in its remembering, should teach us not and never to be inhuman again." Like the water bowels that our society keeps at the entrance of homesteads during funerals, water points are stationed at the exit of Isivivane for visitors to wash their hands when leaving this sacred place. I obliged accordingly and felt good to be African, now that there is a place where an African story is told by an African voice.

Originally posted here:

Freedom Park: Telling the real African story

City freedom plans for Van Morrison

3 September 2013 Last updated at 03:27 ET

Plans to give singer Van Morrison the freedom of Belfast have moved a step closer.

A proposal to grant the honour to the 68-year-old passed without comment during a meeting of the city council.

Members are expected to approve the move during a specially-convened sitting later this month.

Speaking afterwards, the DUP's Gavin Robinson said the east Belfast musician had made an outstanding contribution to civic life.

He said: "Van Morrison has projected a positive image for the city of Belfast through difficult decades with outstanding musical creativity."

I can think of no better individual, who poetically paints a majestic vision of the area I live, love and have the privilege to represent, to receive the honour of freedom

Mr Robinson nominated Morrison for the accolade - the highest a council can bestow.

In his nomination letter, Mr Robinson said: "I can think of no better individual, who poetically paints a majestic vision of the area I live, love and have the privilege to represent, to receive the honour of freedom.

"From humble beginnings, living just behind 'the bright side of the road', Van has rightly achieved international acclaim."

See the original post here:

City freedom plans for Van Morrison