KYTHERA Biopharmaceuticals, Inc. Announces Positive Interim Results from Open-Label Phase IIIb Study of ATX-101 at the …

MONTE CARLO, Monaco--(BUSINESS WIRE)--

KYTHERA Biopharmaceuticals, Inc. (KYTH) today announced positive interim results from a Phase IIIb, multicenter, open-label study (ATX-101-11-26) of ATX-101 during the Innovations and Renewals session of the 11th Anti-Aging Medicine World Congress (AMWC), April 4-6, Monte Carlo, Monaco. The study, presented by investigator Susan Weinkle, MD, FAAD, evaluated the safety and efficacy of ATX-101, a potential first-in-class, non-surgical, injectable drug in Phase III trials for the reduction of unwanted submental fat (SMF), commonly known as double chin. The results found that ATX-101 is well tolerated and may be effective in reducing SMF by both clinician- and patient-reported outcome measures. AMWC is the worlds largest event for global aging management, and attracts aesthetic dermatologists, surgeons and clinicians in the regenerative, preventative and anti-aging medicine industry from more than 95 countries.

The positive interim results are consistent with previous ATX-101 studies, said Weinkle, a board certified dermatologist and affiliate clinical professor at the University of South Florida, Tampa, Fla., U.S. Worldwide, doctors are receiving requests from their patients for a non-surgical way to treat their double chin. The results of this study suggest that microinjections of ATX-101 have an acceptable safety profile and can reduce the appearance of a double chin with high patient satisfaction.

ATX-101 is a proprietary formulation of synthetically-derived deoxycholic acid (DCA), a molecule found in the body that helps break down dietary fat. In this open-label Phase IIIb study, interim results three months after the last ATX-101 treatment are outlined below. Observations were made using validated rating instruments for which one-grade changes are considered to be clinically meaningful:

As previously announced, 71.3 percent of subjects had at least a one-grade improvement on the CR-SMFRS / PR-SMFRS composite and 14.0 percent had at least a two-grade improvement on the same composite measure.

These results are based on a multicenter, 12-month, open-label, Phase IIIb study conducted at 21 sites across the U.S., evaluating 165 adults who received injections of ATX-101 for up to six treatments at four-week intervals. Patients received ATX-101 (2 mg/cm2) by subcutaneous microinjections directly into their SMF, and were evaluated three months after their last treatment. The study population includes females (77.6 percent) and males (22.4 percent) with a mean age of 47, who report at least moderate SMF and dissatisfaction with the appearance of their chin. All Fitzpatrick Skin Types are represented.

We are encouraged by the interim Phase IIIb results of ATX-101, said Frederick Beddingfield, III, M.D., Ph.D., KYTHERAs chief medical officer. The results, along with additional data from our ATX-101 clinical development program, support the potential for ATX-101 to enter the market as the only U.S. Food and Drug Administration (FDA)-approved drug for the reduction of double chin.

ATX-101 is the first pharmacological treatment for the reduction of submental fat to be investigated under a rigorous clinical development program with the goal of seeking regulatory approvals worldwide, specifically in the U.S., Canada and Europe. When injected, ATX-101 targets the fat cells, or adipocytes, and destroys and eliminates them.

The ATX-101 global clinical development program has enrolled more than 2,500 total patients, of which more than 1,500 have been treated with ATX-101.

About ATX-101

Link:
KYTHERA Biopharmaceuticals, Inc. Announces Positive Interim Results from Open-Label Phase IIIb Study of ATX-101 at the ...

Guy DaSilva, MD To Give Workshop On IV Nutrition At Anti – Aging Conference In Orlando, Florida

Guy DaSilva, MD, ABAARM, will be giving a pre-conference workshop on IV nutrition at the 21st Annual World Congress in Anti-Aging and Regenerative Medicine hosted by the American Academy of Anti-Aging Medicine (A4M) on April 11, 2013 in Orlando, Florida.

Sarasota, Florida (PRWEB) April 06, 2013

DaSilvas workshop, The Nuts and Bolts of Traditional IV Therapy, will teach attendees how to integrate and market IV therapies while acquiring specific protocols for chelation, nutrient depletion, fatigue, and other conditions. This will be DaSilvas third presentation of his IV nutrition workshop, which is growing in popularity since its introduction last year.

2012 attendee Dr. Burton Goldberg, an expert in alternative medicine and renowned author in alternative cancer therapies, described the workshop as vital and informative and something every doctor could utilize to become more efficient in the regeneration of the body by feeding the body what the body is screaming for.

2012 attendee Vernon Williams, MD said, The IV nutrition seminar was very helpful. It provided in-depth information on IV nutrition. We were able to incorporate it into our wellness/age management practice. The patients are very appreciative and have been getting us referrals. My office manager will be attending the seminar in Orlando.

Registration Information

Full details on the event, including registration, are available at http://www.a4m.com or by calling 888-997-0112.

About Guy DaSilva, MD, ABAARM

Dr. Guy DaSilva is the founder and medical director of the DaSilva Institute of Anti-Aging, Regenerative & Functional Medicine in Sarasota, Florida, specializing in therapies that naturally reverse disease, restore optimal health, and prevent the destructive process of aging, including nutritional IV therapies that treat a vast array of medical conditions. He is a respected authority in hematology, pathology, internal medicine, and molecular oncology. He is considered an expert in the field of IV nutrition, and has been asked to speak around the country on this topic.

Contact: Dr. Guy DaSilva

Excerpt from:
Guy DaSilva, MD To Give Workshop On IV Nutrition At Anti - Aging Conference In Orlando, Florida

Mad Men Season 6: Nine Things to Know

The Walking Dead Season 3 came to an end last week.

But there is a positive to this development: it means it’s time to go back to the 60s for AMC’s equally entertaining – albeit far less bloody – Mad Men.

I recently spent a day hanging out with the actors that fill the offices of Sterling, Cooper, Draper, Price to see if we could get any scoop out of their tight lips about the new season. Here are 11 things we found out that will get you ready for Sunday’s two-hour premiere...

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Don Draper’s duality: “We open with a man sitting in paradise reading about hell. And I think that's an interesting juxtaposition,” said Jon Hamm, who plays Don and does not utter a line for the first eight minutes of the season premiere. “We see it in the key art and as the season progresses you'll see a lot of dualities and two sides of this person.”

Season 6 Themes: To get a glimpse into what the new season is all about, creator Matthew Weiner broke down this poster: “There is a lot of meaning in it. It came from a dream…I had this dream and it was not Don, it was me. But a lot of stuff is like that. It could be, end up being expressed through Peggy or any of the characters but it was really about -- we don't wanna repeat ourselves on the show. But the fact is that you do repeat things in life. And coming back to a place where things are not so great and starting to realize that maybe you are the problem.”

He also said that one of the characters says in the first episode that 'people will do anything to alleviate their anxiety.’ That's what this season is about.” 

Joan as Partner: “We definitely are sort of exploring the fact that we have seen her all of a sudden become Partner and sort of what that means,” Christina Hendricks previewed. “Are people going to just all of a sudden turn around and, ‘Oh, Joan’s a partner. Let's treat her like a partner’…or is it a title and just everything same as usual?”

The fact that Joan slept with a client to help the business but also secure her partnership won’t be forgotten either, she teased: “It will always be something that she knows she did, but, I think, one of the things I really like about Joan is that she makes a decision, sticks with it, demands not to be judged for it in all sorts of things that she does throughout the show, and I think this is another one of those things.”

Roger, Don and Pete

Is Peggy Gone? Elisabeth Moss said Weiner told her that Peggy leaving the firm did not mean it was over for her. She explained that at season five’s episode 11, the show’s creator “called me and said ‘all this stuff's gonna happen and you're gonna leave.’ I literally was like, ‘that sounds amazing: Am I still on the show?’ He was actually a little bit offended and he was like, ‘Of course! Yes!’”

Moss feels having a main character separate from the rest of the pack, “that’s the beauty of this show, it's not afraid to take that risk, to kind of give the audience a little bit of maybe what they don't want.”

Moss also said she was wrong to assume that it might mean less Peggy Mad Men Season 6: “I was actually pleasantly surprised by how much I had to do in this season. I was kind of expecting not to be in it so much, because I thought well, I'm at a different agency. And I'm pleasantly surprised.”

Megan In The Spotlight: The acting career of Megan (Jessica Paré) goes to higher heights in the new season, but will Don be okay with that?  “We ended last season with Don walking out of the light and into the shadow," Hamm said. "We saw Don leaving Megan in the spotlight and retreating to the shadow. I think that's significant.

A Don and Joan Coupling? Hendricks admitted she loves that the audience wants something to happen between the two characters and isn’t totally ruling it out from ever actually happening: “If it made sense for the characters,” she said, “I am sure if that was something that happened, it would be for a very good reason that Matt would inform us of.”

Jon Hamm, Director: The actor steps behind the camera again for an upcoming episode this season and he admitted it was a tougher challenge this time around: “I had a lot more to do in my episode this season as an actor,” he explained. “It was sort of a degree of difficulty more challenging in that respect. You are completely of two minds on set. It's a very, very difficult mindset to stay in. You're watching one thing as a director and especially if you're in the scene you're watching one thing as an actor.”

He credited watching Ben Affleck wear dual hats while shooting the film, The Town, for helping him take on the task.

Can Roger Keep It In His Pants? John Slattery (Roger) is directing the 10th episode of the season but also talked about whether Roger could ever be faithful to a woman.

“Faithful? I don't know, I don't know. I hope not. Because he really does appreciate people, I think. [His ex-wife] Mona, I think they have a great relationship. I think they sound like each other, Mona and Roger. And Mona and Joan sometimes. They sort of have a way of cutting through the bullshit and pointing something out.”

Sally Parenting Betty: One of the themes with Betty is how she connects with children better than adults yet has a strained relationship with her own kids. Why? “She is on the same emotional level,” explained January Jones, “and I think now Sally is even surpassing her emotional maturity in a way, and has become almost Betty’s parent.”

And while Betty’s second marriage to Henry continues in the new season, can Betty ever be happy? “I don’t think that she’s ever satisfied with her circumstances. It’s just a personality flaw.”

Source:
http://www.tvfanatic.com/2013/04/mad-men-season-6-nine-things-to-know/

Blue Bloods Review: Hate Breeds Hate

It wasn't so much the "Loss of Faith" that I found so sad in this episode of Blue Bloods - but the inability of the people in a beautiful young girl's life to accept that her faith had changed.

Kathleen DeMotto had discovered new love but her death was caused when friends and family reacted with intolerance and hate.  

Death In a Cemetery

Joe couldn't handle that his childhood sweetheart would find someone else, nevermind revert to the Muslim faith. Kathleen's new boyfriend's brother hated her because she wasn't traditional Muslim. She couldn't seem to win.

I felt for Moustafa because of the torture he received as a 12-year old boy after 9/11. It simply proved that hate breeds hate. Where does it end? 

But in the end it was Kathleen's own father who took her out of this world.  He couldn't live with the fact that his little girl could make decisions for herself that he didn't agree with. When she turned her back on their Catholic faith his hold on her literally became deadly. 

Instead of a living Muslim daughter, he has a dead good Catholic girl. I'm sure that in his mind she'll never change.

The Pedro Mendoza story was scary, not only because he was an ex-cop going after other cops but because he could have been almost any guy you passed on the street. 

I like that Jamie and his partner have bonded more. The two may be different but they make a good team. They make me hope that Jamie gets a meatier story line before the season ends. 

As usual the family dinner scene was one of the best of the hour.  I liked how Frank answered when Nicky asked how he would react if Erin was dating a Muslim man.  That his knee-jerk Irish Catholic reaction would be to fight it but his better sense would remind him of what's important. If that man loved his daughter and treated her well, I have no doubt he'd get Frank's blessing no matter what his faith.

Danny's son asking to be Jewish was typical of any child who has seen the fun parts of religious celebration. Bar Mitzvah parties with plenty of presents are awesome but Hebrew school and giving up bacon, less so. 

As Frank pointed out in this funny Blue Bloods quote

Bacon. The ultimate test of faith. | permalink

Truer words were never spoken. It's great to have Blue Bloods back.

Source:
http://www.tvfanatic.com/2013/04/blue-bloods-review-hate-breeds-hate/

Grimm Review: Dropping Toad

"One Angry Fuchsbau" was a rather modest episode for Grimm Season 2.

The callbacks, small moments and humor made for a fun, but mostly lighthearted installment. But that's about it.

On The Jury

The references to “La Llorona’s” spiritual grandma reminded us Juliette’s upcoming choice and further shed a little bit more on the type of decisions and world’s she’s about to enter: one filled with light or one filled with darkness.

Juliette isn’t sure what is real and what isn’t and the choice she’s going to make is going to lead her to a world with light or a world covered in darkness. I have a difficult time buying that Juliette’s dilemma has anything to do with the traditional good and evil archetypes because Grimm is never anything close to traditional and Juliette, for all her annoyances and faults, is a genuinely good character.

Juliette’s choice could end up being far simpler: a world filled with light is a world where she knows the truth, and a dark world is a world where she’s oblivious to what’s going on. The Grandma again reminds her that she has a choice to make, but, hypothetically, Juliette has already experienced a world filled with darkness. She’s currently living in it. She’s haunted by her reemerging memories of Nick; it’s literally a world where there’s a dark spot in her life.

If Juliette chooses to embrace those memories of Nick and to believe what he told her about the trailer and him, she’s in a world of light or enlightenment. She just needs to find the mental courage and fortitude to take the leap.

The longer arcs for the season didn’t get much play time with Renard getting a whopping single scene to clue Nick and Hank in on who went after him and to remind us of the Verrat. I guess he was such a badass last week he needs to be relegated to a few sentences to make up for it.

A Few More Thoughts:

  • Mama Burkhardt is dropping Nick an email to check in. I hope this means we’ll get a return visit from her before the season is out.
  • Adalind already has the pregnancy glow and Eric is planning a trip to see Renard.
  • “Dropping toad” and Monroe’s entire scene trying to inject that frog is probably the most humorous Grimm has ever gone. I hope we can see Grimm’s sense of humor more often.

Source:
http://www.tvfanatic.com/2013/04/grimm-review-dropping-toad/

Vegas Review: Every Girl Deserves a Cowboy

"Little Fish" featured the Vegas girls leaving town and the cowboys on the losing end…or so it seemed.

Jack Attacks Savino

Apparently Frank Blackwell likes his hookers young, which turned out to be a problem for the Savoy. As I watched, I contemplated how things have changed. Would 17 still be legally considered a minor in most states if this case happened today?

I know Ralph wanted to help the girl but he was sure quick to turn on Catherine when she had to let Patricia go.  There's bending the rules and then there's not following the law at all.  Catherine had no legal right to hold Patricia, although perhaps someone should have asked the mom to show some ID. Not that it wouldn't have been easy enough to fake one in 1960.

Mia has turned out to be one of the strongest characters one the show.  She gave Patricia a new life in a way that no one else could and then made sure Frank understood exactly what would happen to him if he ever ratted on the details of the skim from her count room.  Frank should consider himself lucky. If his conversation had been with Savino it probably would have ended up under six feet of desert. 

It's good to know that Mia has her doubts about Vince. He never gave her a straight answer to her question about telling Rizzo she was a rat. Mia's smart enough to spot a dodge when she sees one.

I had no idea what Jack was thinking when he assaulted Savino in his own office.  It appeared reckless and foolish and he was lucky not to get arrested or killed. Then the other shoe dropped.

Jack planted a bug in Savino's phone. I wonder when wire tapping laws went into effect. My guess is it wasn't in 1960.

It was funny listening to Savino lament about his fish having scale rot. It seems big time mobsters have small time problems too.

Dixon was very cute as he couldn't take his clothes off fast enough to jump in the pool with Violet. They make a sweet couple but I don't know what he expects when he gets to Los Angeles. Violet likes him but I don't see her walking away from her life long dream of becoming a starlet just to be his girlfriend back in Vegas.

Yvonne was a surprise. The girl can definitely sing. I wouldn't mind seeing the look on her face when she has her first real pastrami sandwich either. She'll understand the need to have one delivered from 300 miles away.

Will Mia ever give Jack a second chance?  Will Yvonne or Violet make it big in Hollywood? Is there any hope for a relationship between Ralph and Catherine? 

After a hiatus of several weeks, are you happy to be back in Vegas?

Source:
http://www.tvfanatic.com/2013/04/vegas-review-every-girl-deserves-a-cowboy/

Nikita Review: Freedom or Death?

At first, "Tipping Point" appeared to be a Nikita episode about Michael getting a fully operational arm again. But turned into so much more. Wow. 

What a freaking twist! I didn't see it coming at all, did you? Even on my second viewing of the episode, I didn't find any glaring clues the Alex was behind the mutiny. It was obvious that Amanda did something to her, but the extent of Alex's shift in mind frame was utterly shocking. Kudos to the writers and to Lyndsy Fonseca for her outstanding performance.

Considering Prosthetic

In "Inevitability," Ryan and Nikita took back total control of Division and re-committed to bringing in the Dirty Thirty, shutting down Division, and getting everyone their freedom. They completely shut down Division's role in black operations for the US government. While the search for the Dirty Thirty may have been happening in the background, Michael set out on his own to find a better solution to replace his artificial arm.

Heidecker may have been trafficking in children, but his organization named "The Shop" by Birkhoff had the capability to replace Michael's arm and he wasn't going to ignore that option. He headed out on his own to get the data to find them. What started out as a simple mission for Michael and Nikita turned into something much more dangerous for them and unexpectedly for the safety of Division.

While it makes sense that Michael would want to get a working arm back, was the cost worth it? Jason died after he volunteered to help infiltrate the Chinese company and steal the prion in exchange for a new arm. He gave his life for Michael's arm. That alone was an enormous cost, but it had even farther reaching consequences.

After Alex revealed that the US government was willing to exterminate everyone at Division, a mutiny was formed. Rachel and others were working on a plan to escape from Division. Their initial plan to blow up the tracker data on the Division servers failed, but they were determined to come up with another way. After Jason died on a side mission for Nikita and Michael, the mutiny's recruitment expanded.

At first, I couldn't understand why they wouldn't trust Ryan and Nikita after they revealed everything. Though, after considering what I would do if I was in Rachel's position, it made more sense. Percy, Amanda, and even Ryan and Nikita lied to them. Why would they believe them now? After everything they have been through, why wouldn't they take matters into their own hands now that they can?

Only they don't understand the greater consequences of their actions. A mutiny could force the government to take final and complete action to get rid of Division. The mutineers are unwittingly putting them all in danger. In order to shut it down and protect everyone, Sean set up a trap and it caught Rachel. She was the one that hacked the computer system to allow access to the server room.

She may have claimed to be the leader, but she messed up. IT WAS ALEX! What?!?! That was such a shock. Even though it was clear that Alex hadn't been herself since South Ossetia, it never crossed anyone's mind that she was involved with the mutiny. Amanda manipulated Alex's memories about her time in the brothel and transferred her regrets over not saving the girls there to the operatives at Division.

Alex was determined to rewrite her history by being the savior of the souls at Division. And, she went as far as shooting Ryan and then convincing Rachel to take the fall. Alex may be somewhat delusional, but she still has her training. Going forward, will Alex be able to keep her true intentions a secret from those around her? Especially from Sean? 

It was disappointment to see Alex go through with the mutiny plans, shoot Ryan, and use Rachel to cover it up even after hearing Nikita's plan for dealing with the mutineers. Nikita gave Alex an out, but she wasn't able to overcome Amanda's programming to see the right path to take.

Nikita: We're going to march them out in front of everyone ... and we're going to forgive them. This isn't the old Division anymore. | permalink

There is some hope that Alex will reveal herself though. After Rachel was captured, Alex and Nikita had a discussion about her plan and the ultimate outcome. It provided insight into Alex's beliefs on the matter and if she continues to be that open, Nikita will see through her.

Nikita: So she wants us all dead.
Alex: She wants everyone to be free. | permalink

Or, perhaps, Nikita will get through to Alex that if the mutiny succeeds that it won't end in freedom, but in death for them all. Either way, it's a dangerous road that's ahead for everybody at Division. Plus, now there is a potential additional threat from "The Shop." And, of course, Amanda is still out there and determined to make Nikita pay.

Were you shocked when Alex was revealed as the leader of the mutiny? Should Michael have made the deal to get a new arm? Who is the biggest threat to Division right now? Mutiny? Amanda? The Shop?

Source:
http://www.tvfanatic.com/2013/04/nikita-review-tipping-point/

Happy Endings Review: Sister Act and Star Crossed Lovers

Never before has Dave's steak truck gotten so much attention in two consecutive Happy Endings episodes!

In "The Incident," Penny accidentally got the truck stolen when she borrowed it to move furniture. In the second installment, "Bros Before Bros," Dave went to war with a fellow steak truck owner known as "The Brazilian."

The Happy Endings happy hour was filled with sisterly fights, forbidden romances and a life sized Brad doll. Let's discuss.

Penny's Wedding Day

In the first half of the hour, Max's hairdresser died and he needed a replacement. After trusting Dave for some stupid reason, he ended up looking like his clone, highlighted goatee and all. Jane and Alex to the rescue! Besides better skills, Jane and Alex's hair dresser played by RuPaul had a major advantage: gossip. Max being Max, he was obviously enticed and went to town with his new information. He's a troublemaker, he couldn't resist!

Everybody knows there are just certain things that are better left unsaid, especially within families. I have four siblings all who are married so I technically now have 8. You gotta know when to pick and choose your battles. Sometimes airing your grievances can just make it all worse, especially when you're Jane and Alex. The girls fighting went all the way back to childhood when there was an all out cold war. 

Max and Brad did a little digging and found an article that talked about how the girls made up. Question posed by Max, what's creepier: the random anatomically correct doll of Brad or the fact that a local newspaper was super obsessed with Jane and Alex? At least the paper had some answers. Nana Kerkovich to the rescue and all was right in the world again! Also Dave found his truck and had to sanitize it after the guy who stole it, admitted to making love to the meat...literally.

On to the second episode: Steak Me Home Tonight got even more attention as Dave braced for opening day at Wrigley field when he'd have to face his steak truck rival: The Brazilian. With the girls off planning Penny's wedding, the boys helped Dave plot to win the steak-off. Sidenote, how timely was Alex's comment about North Korea:

You had Jane plan you a backup wedding in an underground bunker just in case North Korea quote grew a pair, but you never thought of who's gonna walk you down the aisle? | permalink

What's scary about that timely and relevant comment was that it was made my Alex. Did you see her 4th grade book report that Max found? "F, is this a joke?" Amazing. Enter Penny's long lost dad who abandoned her to be an actor at a young age. He had a hard road with having to impress Jane, but he managed to do so after buying Penny her dream dress and getting involved in the steak truck showdown.

That showdown may never have happened but of course Max had to make trouble once again and sleep with the competition's son. Oh Max, what are we going to do with you? If it weren't for the fact that your actions resulted in a Ladybugs reference, I might have been kinda mad at your for messing things up for Dave!

He's not lying. He once Ladybugs'd himself into a Jr. High girls soccer tournament, bet against the team, and threw the game. | permalink

Amazing and under-appreciated movie reference. This is why I love Happy Endings! I thought this week's back to back episodes were better than last weeks. How about you guys? Hit the comments! 

Source:
http://www.tvfanatic.com/2013/04/happy-endings-review-sister-act-and-star-crossed-lovers/

Space station detector gives first clues to ‘dark matter’

STORY HIGHLIGHTS

(CNN) -- Nearly two years after it was sent up to the International Space Station, a giant particle physics detector has provided its first results in the search for the mysterious "dark matter" believed to be a major component of the universe.

The international team running the Alpha Magnetic Spectrometer released its initial findings Wednesday at the European Organization for Nuclear Research, known as CERN, in Switzerland.

The scientists are studying flux in cosmic rays, the charged high-energy particles that permeate space, for evidence of the invisible dark matter particles colliding with each other, leading to what is termed "annihilation."

A result of this would be a higher presence of the charged particles known as positrons, the antimatter counterpart of electrons.

According to a CERN statement, the results announced Wednesday "are consistent with the positrons originating from the annihilation of dark matter particles in space, but not yet sufficiently conclusive to rule out other explanations."

How particle smasher and telescopes relate

Over the last few decades, scientists have come to the conclusion that the universe's composition is only about 5% atoms -- in other words, the stuff that we see and know around us. That means the rest is stuff we can't see. About 71% is something called "dark energy," and another 24% is "dark matter."

Research is ongoing to figure out precisely what these "dark" components are, because they do not interact with ordinary matter and have never been directly detected.

The Alpha Magnetic Spectrometer project is being jointly run by scientists from 16 countries, under the leadership of Prof. Samuel Ting of the Massachusetts Institute of Technology.

Original post:

Space station detector gives first clues to 'dark matter'

Cameras set for fall launch to space station and to start streaming by year-end

By Peter Rakobowchuk, The Canadian Press

MONTREAL - A Vancouver-based company says it should be ready to take videos of big outdoor events on Earth from the International Space Station and put them on the Internet by the end of the year.

Scott Larson, the CEO of Urthecast, says two space cameras one that shoots photos, the other video will be sent up to the station on Oct. 16 on board a Russian spacecraft.

The cameras will be installed on the outside of the football-field-sized station at the end of October and are expected to start rolling a few months later once tests are completed.

"Around the last couple of weeks of December or the first couple of weeks of January is when we'll be able to officially turn stuff on and start showing all the streaming images," Larson told The Canadian Press.

He said there will be about a one-hour delay before the images taken by the space station cameras show up on Urthecast's website, but there will be lots to feast on.

"Anything that's one metre big is what you'll be able to see," he said. "You'll see if there are 10 people together in white shirts in a green field.

"If we decide there's something over a downtown that we want to see, we can point the video camera, hold it for about 90 seconds and then it goes on to the next target."

The cameras will be able to show flash mobs, outdoor events, stadiums, boats and planes, but Larson added that images like people's faces and licence plates will be too small to be visible.

The Urthecast executive also said people will be able to find out in advance when the space station and its cameras will be flying over their area.

Excerpt from:

Cameras set for fall launch to space station and to start streaming by year-end

NASA Sees Curiosity Rover’s Parachute Flapping in Martian Wind (Video)

NASA's most powerful spacecraft orbiting Mars has captured amazing new images of the huge parachute used by the agency's Curiosity rover when it safely landed on the Red Planet last August.

A video of the NASA images of Curiosity's parachute shows it billowing in the Martian wind. The views were recorded by NASA's Mars Reconnaissance Orbiter currently circling the planet.

In all, the MRO spacecraft captured seven photos of Curiosity's huge parachute flapping on the surface of Mars. The images were taken between last Aug. 12 and Jan. 13 using the orbiter's powerful High Resolution Imaging Science Experiment camera, known as HiRISE.

"This sequence shows distinct changes in the parachute," NASA officials explained in an image description. "In the first four images, there are only subtle changes, perhaps explained by differences in viewing and illumination geometry." [See amazing Mars photos by Curiosity]

At some point between Sept. 8 and Nov. 5 (featured in MRO's fourth and fifth photos in the parachute sequence), the parachute underwent a major change in position, in which part of the parachute shifted inward. The move was accompanied by a change in the terrain around the parachute, possibly from dust being kicked up as the parachute moved.

Another movement occurred between Dec. 16 and Jan. 13, when the parachute shifted toward the southeast.

"This type of motion may kick off dust and keep parachutes on the surface bright, to help explain why the parachute from Viking 1 (landed in 1976) remains detectable," wrote planetary scientist Alfred McEwen, the principal investigator for MRO's HiRISE camera at the University of Arizona, in a statement.

NASA's Mars rover Curiosity landed on the Red Planet on Aug. 5. During its descent, the MRO spacecraft used its HiRISE camera to spot the rover descending under its parachute, just before dropping free to begin the risky "sky crane maneuver" that ultimately lowered it down to its Gale Crater landing site.

"Researchers have used HiRISE to study many types of changes on Mars," NASA officials said in a statement. "Its first image of Curiosity's parachute, not included in this series, caught the spacecraft suspended from the chute during descent through the Martian atmosphere."

Curiosity's main parachute was the largest parachute ever used for a Mars landing. When it was fully deployed, the parachute measured 51 feet (15.5 meters) across.

More:

NASA Sees Curiosity Rover's Parachute Flapping in Martian Wind (Video)

Sen. Bill Nelson unveils NASA plan to capture asteroid

NASA plans to lasso an asteroid and park it by the moon, and they say they can put astronauts on it by 2021.

An artist concept shows the Orion Capsule as it will appear in space for the Exploration Flight Test-1 attached to a Delta IV second stage. (Image credit: NASA)

Senator Bill Nelson of Florida announced Friday that Barack Obama and NASA have plans to send a robotic spaceship to capture a small asteroid and bring it closer to Earth. Astronauts would be able to explore the asteroid by 2021.

Nelson, chairman of the Senate Science and Space Subcommittee, said Friday that Obama is putting $100 million for the asteroid mission in the 2014 budget due out next week, reports Bay News.

This is part of what will be a much broader program, Nelson said in Orlando. The plan combines the science of mining an asteroid, along with developing ways to deflect one, along with providing a place to develop ways we can go to Mars.

Their jointly produced Asteroid Retrieval Feasibility Study suggests that bringing a 500-ton asteroid closer to Earth would give astronauts a unique, meaningful and affordable research destination for the next decade.

Astronauts aboard Americas Orion capsule will be sent into space on a massive new rocket called SLS, capable of lifting enormous payloads far beyond low-Earth orbit. The U.S. hasn't had a rocket capable of this since 1972. Nelson and former U.S. Sen. Kay Bailey secured approval for the SLS in 2010.

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Sen. Bill Nelson unveils NASA plan to capture asteroid

NASA to lasso asteroid, bring it closer

By Seth Borenstein

NASA is planning for a robotic spaceship to lasso a small asteroid and park it near the moon for astronauts to explore, a top senator said Friday.

The ship would capture the 500-ton, 25-foot asteroid in 2019. Then using an Orion space capsule, a crew of about four astronauts would nuzzle up next to the rock in 2021 for spacewalking exploration, according to a government document obtained by The Associated Press.

Senator Bill Nelson, Democrat-Florida, said the plan would speed up by four years the existing mission to land astronauts on an asteroid by bringing the space rock closer to Earth.

Nelson, who is chairman of the Senate science and space subcommittee, said Friday that US President Barack Obama is putting US$100 million in planning money for the accelerated asteroid mission in the 2014 budget that comes out next week. The money would be used to find the right small asteroid.

"It really is a clever concept," Nelson said in a press conference in Orlando. "Go find your ideal candidate for an asteroid. Go get it robotically and bring it back."

This would be the first time ever humanity has manipulated a space object in such a grand scale, like what it does on Earth, said Robert Braun, a Georgia Institute of Technology aerospace engineering professor who used to be NASA's chief technology officer.

"It's a great combination of our robotic and human capabilities to do the kind of thing that NASA should be doing in this century," Braun said.

Last year, the Keck Institute for Space Studies proposed a similar mission for NASA with a price tag of US$2.6 billion. There is no cost estimate for the space agency's version. NASA's plans were first reported by Aviation Week.

While there are thousands of asteroids around 25-feet, finding the right one that comes by Earth at just the right time to be captured will not be easy, said Donald Yeomans, who heads NASA's Near Earth Object programme that monitors close-by asteroids. He said once a suitable rock is found it would be captured with the space equivalent of "a baggie with a drawstring. You bag it. You attach the solar propulsion module to de-spin it and bring it back to where you want it."

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NASA to lasso asteroid, bring it closer

NASA to get $100 million for asteroid mission, senator says

Rick Sternbach / Keck Institute for Space Studies

An artist's illustration of an asteroid retrieval spacecraft capturing a 500-ton asteroid that's 7 meters wide.

By Mike WallSpace.com

NASA will likely get $100 million next year to jump-start an audacious program to drag an asteroid into orbit around the moon for research and exploration purposes, U.S. Sen. Bill Nelson, D-Fla.,says.

The $100 million will probably be part of President Barack Obama's federal budget request for 2014, which is expected to be released next week, Nelson said. The money is intended to get the ball rolling on the asteroid-retrieval project, which also aims to send astronauts out to the captured space rock in 2021.

"This is part of what will be a much broader program," Nelson said Friday during a visit to Orlando. "The plan combines the science of mining an asteroid along with developing ways to deflect one, along with providing a place to develop ways we can go to Mars."

NASA's plan involves catching a near-Earth asteroid (NEA) with a robotic spacecraft, then towing the space rock to a stable lunar orbit, Nelson said. Astronauts would then be sent to the asteroid in 2021 using NASA's Orion capsule and Space Launch System rocket, both of which are in development.

The idea is similar to one proposed last year by researchers based at Caltech's Keck Institute for Space Studies in Pasadena.

"Experience gained via human expeditions to the small returned NEA would transfer directly to follow-on international expeditions beyond the Earth-moon system: to other near-Earth asteroids, (the Mars moons) Phobos and Deimos, Mars and potentially someday to the main asteroid belt," the Keck team wrote in a feasibility study of their plan.

NASA will need much more than this initial $100 million to make the asteroid-retrieval mission happen. The Keck study estimated that it would cost about $2.6 billion to drag a 500-ton space rock back near the moon.

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NASA to get $100 million for asteroid mission, senator says

NASA puts Mars rover on a month-long hiatus

NASA halts communication with Curiosity to avoid any interference during a period when the sun is blocking Earth-to-Mars transmission signals.

NASA's Mars Science Laboratory rover -- Curiosity -- explores the surface of the red planet in this artist's concept.

For the first time since its descent onto the red planet, the Mars rover Curiosity is getting a little alone time.

The rover and NASA scientists are having a communication breakdown, of sorts. But, not to worry, no hurt feelings are involved. The issue is that the sun has got in the way.

Once every 26 months, as the Earth and Mars rotate around the sun, the two planets end up on opposite sides of the star in an event called the Mars solar conjunction. Because of the sun's massive size, any communication sent between the two planets can be easily disrupted.

"We have plenty of useful experience dealing with them, though each conjunction is a little different," Chris Potts, NASA's mission manager for the Mars Odyssey rover, said in a statement. "The biggest difference for this 2013 conjunction is having Curiosity on Mars."

To prepare for the month off, NASA scientists give the rovers directions of what to do beforehand, which keeps the rovers busy working during those weeks. According to NASA, Curiosity may have up to 12 GB of data accumulated by the time it can make contact with NASA again.

Communication with Curiosity was suspended today and is expected to be back up again around May 1.

Here's a video from NASA's Jet Propulsion Lab explaining the signal breakdown between NASA and the rovers during a Mars solar conjunction:

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NASA puts Mars rover on a month-long hiatus