Monthly Archives: January 2013

Proteonomix Updates Status Of UMK-121 Testing

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PARAMUS, N.J., Jan. 8, 2013 /PRNewswire/ -- Proteonomix, Inc. (the "Company")(Symbol PROT), a biotechnology company (the "Company") focused on developing therapeutics based upon the use of human cells and their derivatives, announced today that the University of Medicine & Dentistry of New Jersey (UMDNJ) in conjunction with the Company has commenced enrollment of patients with End Stage Liver Disease (ESLD) in its clinical trial of UMK-121.

Michael Cohen, President and CEO of the Company, stated; "We have began to screen new patients for the UMK-121 trial and have enrolled our first candidate into the trial. We expect to enroll more patients in the upcoming months. The treatment of our first patient on the UMK-121 trial is a major step forward for the company and demonstrates the company's ability to move new therapies into therapeutic testing. Two additional trials of UMK-121 are presently being developed in cancer and heart diseasewhich we intendto initiate in 2013."

About Proteonomix, Inc.

Proteonomix is a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives. The Proteonomix family of companies includes Proteoderm, StromaCel, PRTMI and THOR Biopharma. Proteoderm is a wholly owned subsidiary that has developed an anti-aging line of skin care products. StromaCel develops therapeutic modalities for the treatment of cardiovascular disease and for treatment of patients who have suffered post-myocardial infarction. Proteonomix Regenerative Translational Medicine Institute, Inc. (PRTMI) intends to focus on the translation of promising research in stem cell biology and cellular therapy to clinical applications of regenerative medicine. Additional information is available at http://www.proteonomix.com and http://www.proteoderm.com.

Forward-looking statements:

Certain statements contained herein are "forward-looking statements" (as defined in the Private Securities Litigation Reform Act of 1995). Proteonomix, Inc. cautions that statements made in this press release constitute forward-looking statements and makes no guarantee of future performance. Actual results or developments may differ materially from projections. Forward-looking statements are based on estimates and opinions of management at the time statements are made.

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Proteonomix Updates Status Of UMK-121 Testing

The Fleshlettes

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Jonathan Payne Fleshlettes

Jonathan Payne Fleshlette Tonya
“This is Tonya, she’s the matriarch of the Fleshlette family.”

 

Jonathan Payne Fleshlette Toni
“This is Toni. She smells. None of the other girls pick her to be on their team. She can type 90 wpm.”

 

Jonathan Payne Eileen Fleshlette
“She is named Eileen (for obvious reasons).”

 

Jonathan Payne Richanda Fleshlette
“Here is Richanda, the 6th fleshlette. She is similar to the others except for one key difference: her singing voice.”

 

Jonathan Payne Fleshlette Gisele
Gisele

 

Are they making you slightly uncomfortable?  These little “tumorous balls of flesh”, called Fleshlettes, are the creation of California-based artist Jonathan Payne who specializes in creature and character design. Sculpted from materials like super sculpey, polymer clay, acrylic, and even human hair, each Fleshlette has a name and unique personality. They’re so grotesque they’re almost cute…

 

[spotted by Steven Trotta via Design Taxi]

 

Source:
http://feedproxy.google.com/~r/streetanatomy/OQuC/~3/mIDFg_Nziro/

Microwave chemistry – should we blame the tools?

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Microwaves - not magic

— Microwaves – not magic

In an essay article in Angewandte Chemie, Oliver Kappe from the University of Graz, Austria, is trying to lay to rest the idea that microwave reactors can accelerate chemical reaction by doing anything other than heating.

The main thrust of the argument is that it is essentially impossible to accurately measure the temperature of a reaction mixture without a direct, internal fibre-optic probe. Using the external infrared sensors fitted to most microwave reactors simply doesn’t cut it if you really want to work out whether what you’re seeing is really a special effect of microwave irradiation, or just an artefact of differences in heating.

To illustrate the point, Kappe and his team repeated experiments from two recent publications. The first came from Gregory Dudley at Florida State University in Tallahassee, US, and was covered in Chemistry World at the time.

Dudley and his team made great efforts to try and separate the bulk heating effect of microwaves from specific interactions with certain molecules in their reaction mixture, taking inspiration from Kappe’s own work in the experimental design. They compared reactions run in the microwave to reactions at the same temperature using conventional heating baths, and the results seemed to indicate that the microwave reactions were more efficient.

However, Kappe asserts that the external IR sensors employed by Dudley to monitor the reaction temperature were inadequate. When Kappe and his team repeated the experiment, using their internal fibre-optic probe, they found no difference between the microwave and conventionally heated reactions, and also that they needed less microwave power (on the same type of reactor) to maintain the reaction temperature, indicating that Dudley’s microwave reactions were probably running at a higher temperature, which is what was causing the rate enhancement.

Similarly in the second example, when Kappe’s team tried to reproduce experiments monitored using external IR sensors with their internal fibre-optic probe, the apparent non-thermal microwave effect disappeared.

So what is the message? Kappe is certainly not trying to discourage researchers from using microwaves – they are a great tool for speeding up chemistry, allowing reactions to proceed in superheated solvents at enhanced reaction rates.

However, when it comes to claims that these rate enhancements are due to anything other than thermal effects, he is simply saying that extraordinary claims require extraordinary evidence, and that means you really need to be able to measure temperature accurately. Kappe suggests that the best way to do this is to combine internal fibre optic probes with external IR measurements, and any paper in which measurements are not made with internal fibre optic probes should be treated with scepticism.

This technology is already available on the latest generation reactors, but they are expensive pieces of kit, so how many labs are likely to upgrade? In industrial labs, where simply being able to make a compound for testing is often of greater importance than the exact conditions used, this may be less of an issue. And how many academic researchers can afford it?

Phillip Broadwith

 

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Source:
http://prospect.rsc.org/blogs/cw/2013/01/09/microwave-chemistry-should-we-blame-the-tools/

This Thursday Night at Observatory: "Natural Histories: Extraordinary ?Rare Book Selections from the American Museum of Natural History Library"? with Tom Baione of AMNH

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This Thursday, January 10, I am so very excited to be hosting my former colleague at the American Museum of Natural History--library director Tom Baione--at Observatory. He will be talking about--and showing scores of amazing illustrations from!--a variety of rarely seen illustrated books residing in the museum's research library special collections as explored in his new book Natural Histories: Extraordinary ?Rare Book Selections from the American Museum of Natural History Library?. We will also have twenty copies of this gorgeous book--which  features forty suitable-for-framing art prints of images from the book--available for sale and signing by Mr. Baione!

Full details follow. Hope very much to see you there!

Natural Histories: Extraordinary ?Rare Book Selections from the American Museum of Natural History Library: Illustrated lecture and Book Release Party with Tom Baione of New York’s American Museum of Natural History
Date: Thursday, January 10
Time: 8:00 PM
Admission: $5
Presented by Morbid Anatomy
*** Copies of the book will be available for sale and signing

Most people are well acquainted with the front-stage wonders of New York's American Museum of Natural History--the world class habitat group dioramas, the highly stylized hall of biodiversity, the epic dinosaur skeletons; what is less well known is the equally astounding back-stage collection, which includes an world-renowned collection of exquisite, rare, and beautifully illustrated books on the natural sciences held by museum's research library. The new book Natural Histories: Extraordinary ?Rare Book Selections from the American Museum of Natural History Library?, edited by AMNH's Tom Baione, brings these hidden works to the fore, showcasing forty extraordinary works created between the 16th and 20th centuries, covering all seven continents, and spanning such diverse scientific fields as anthropology, astronomy, earth science,? paleontology, and zoology. The book also features essays about each work by Museum curators, scientists, and librarians, as well as forty extraordinary, suitable-for-framing art prints of images from the book.

In tonight's highly illustrated lecture, join American Museum of Natural History's Boeschenstein Director of? Library Services and volume editor Tom Baione for a look inside the Natural Histories... and a virtual trip behind the scenes of the Library's Rare Book Room. Attendees will also have the opportunity to purchase--and have signed!--their own copy of this gorgeous new volume.

Tom Baione, a Brooklyn native, started working in the Museum's Library in 1995 ?after attending Pratt Institute's School of Library and Information? Science. After years in the Library's Special Collections and Reference ?Services units, Tom became the Library's Director in 2010. He is an active? member of New York's Grolier Club and lives in midtown with his high?school sweetheart. The Museum was his favorite childhood destination and he still reports a thrill upon entering the museum each day.

More here.Source:
http://morbidanatomy.blogspot.com/2013/01/this-thursday-night-at-observatory.html

Things Explained: Nigel Holmes explains how nanotechnology works and what you can do with it – Video

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Things Explained: Nigel Holmes explains how nanotechnology works and what you can do with it
Nigel Holmes is co-author (with Steven Abbott) of Nano Coatings - Principle and Practice. In this clip, he talks about: what nano particles are; what applications nano particles have; its uses for electronics and coatings; the financial scale of the nano-coatings industry; and the use of silicon dioxide nano particles in screen coatings.

By: SmartMonkeyTV

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Things Explained: Nigel Holmes explains how nanotechnology works and what you can do with it - Video

Nigel Holmes on the size of the nanotechnology industry, the big players and problems of scaling up – Video

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Nigel Holmes on the size of the nanotechnology industry, the big players and problems of scaling up
Nigel Holmes is co-author (with Steven Abbott) of Nano Coatings - Principle and Practice. In this clip he talks about: the size of the nano coatings industry; which companies are big in nanotechnology and which countries are strong in nanotechnology; where the academic research expertise is currently found; and the problems of scaling up for industrial production.

By: SmartMonkeyTV

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Nigel Holmes on the size of the nanotechnology industry, the big players and problems of scaling up - Video

Nigel Holmes on the health and safety implications of nanotechnology – Video

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Nigel Holmes on the health and safety implications of nanotechnology
Nigel Holmes is co-author (with Steven Abbott) of Nano Coatings - Principle and Practice. In this clip, he talks about: the fears about the safety of nanotechnology products; the existence of nano particles in everyday life already; the concerns about certain types of nano particles; the industry #39;s awareness of these problems and the research being done to look at them.

By: SmartMonkeyTV

See the article here:
Nigel Holmes on the health and safety implications of nanotechnology - Video