Free Weekly Clinic Run by Medical Students Helps Patients Get Essential Care

Students gain skills & understanding while serving uninsured patients under supervision of faculty doctors

Newswise ANN ARBOR, Mich. Uninsured residents of rural Livingston County, Mich. and surrounding areas who need health care have a new option to turn to every Saturday afternoon: a free medical clinic run entirely by University of Michigan Medical School students.

The students, and U-M faculty physicians, volunteer their time to provide free primary care each week at a storefront clinic in Pinckney.

The U-M Student Run Free Clinic, as it is called, uses the same location as the Faith Medical Clinic, a free-care site for patients without insurance that offers appointments on Thursday evenings and Saturday mornings. On the afternoon of Oct. 6, the team will hold an Open House to welcome the community.

For the U-M students, the free clinic is not just a chance to give back to the community its also a chance to get to learn more about opportunities to care for the uninsured and to know the administrative and business side of medicine.

Students plan for and handle all the details and challenges of running the clinic, and deal with everything from appointment scheduling and interviewing new arrivals, to entering information into a computerized medical record system. The U-M Medical School Deans office is providing funding, as is Michigan Central Student Government.

Already in the clinics pilot period, the students and their faculty supervisors have seen patients with everything from simple ailments to chronic conditions such as hypertension, diabetes and shoulder joint issues.

The students handle all aspects of the visit except for those that require a licensed physician -- a role filled by a faculty physician from the Medical School. Patients who need more advanced care receive a referral and help in finding low-cost or free options, including through the U-M Health Systems own charity care program.

The U-M Student Run Free Clinic gives our students a real sense of all the moving parts that must be aligned to create a well-run clinic, the issues facing the uninsured and the importance of caring for all in our communities, says Hari Conjeevaram, M.D., M.Sc., an associate professor of internal medicine who is the lead faculty advisor to the clinic team and medical director of the clinic. Although health care reform should give more uninsured Americans access to care over the next few years, services like the Faith Clinic and our student-run clinic provide a vital safety net for non-emergency and preventive care.

The experience of running the clinic and taking patients vital signs and medical histories is especially important for the first- and second-year medical students, whose classroom studies dont yet bring them into contact with patients.

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Free Weekly Clinic Run by Medical Students Helps Patients Get Essential Care

Opponents raise questions over proposed UT medical school

by MARK WIGGINS / KVUE News and photojournalist SCOTT MCKENNEY

kvue.com

Posted on September 24, 2012 at 6:25 PM

Updated yesterday at 6:41 PM

AUSTIN -- Posters popping up across town urge passers-by to "stop the bleeding." They are signs that opposition to a new University of Texas medical school and teaching hospital in Austin is organizing.

"We say that the way to keep Austin healthy is to 'stop the bleeding,'" said Don Zimmerman, founder and treasurer of the Travis County Taxpayers Union, a political action committee (PAC) dedicated to opposing a tax increase to fund the project. The committee is a counterpart to Keep Austin Healthy, a PAC created by supporters of the project.

Zimmerman argues a five-cent increase proposed by Central Health, equivalent to about $100 a year on a $200,000 home, is too much to ask of a community that has seen property taxes steadily rise.

"We're dying a death by a thousand cuts," said Zimmerman. "Each one of these taxes and each one of the tax increases by itself doesn't drive you out of your home, but when you add up all the property taxes and all the increases, people are literally being taxed out of their homes."

Along with investment from the University of Texas and Seton Healthcare Family, State Senator Kirk Watson (D-Austin) says the $35 million contributed by Austinites through a tax increase would be matched by more than $86 million in federal Medicaid funds.

Watson contracted TXP, Inc., an Austin-based consulting firm specializing in economic analysis, to study the impact of the project. Speaking with KVUE in August, president and founder Jon Hockenyos provided a detailed breakdown of economic data predicting a gain of 15,000 jobs and roughly $2 billion in economic activity as a result of the project.

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Opponents raise questions over proposed UT medical school

Scripps study on PTSD symptoms released

SAN DIEGO -

Symptoms of Post-Traumatic Stress Disorder are eased by a combination of guided imagery and a specific type of therapy called "Healing Touch," the Scripps Center for Integrative Medicine announced Monday.

Results of a study of 123 Marines who returned from deployment to Camp Pendleton between July 2008 and August 2010 were released in the September issue of the publication Military Medicine. Those selected were experiencing traumatic flashbacks, nightmares, emotional numbness, insomnia and other PTSD symptoms.

The 68 participants who went through six sessions over three weeks with Healing Touch and guided imagery fared much better than the 55 who received normal treatment, according to Scripps.

"Scores for PTSD symptoms decreased substantially, about 14 points and below the clinical cutoffs for PTSD," said Dr. Mimi Guarneri, a Center for Integrative Medicine founder. "This indicates that the intervention was not just statistically significant, but actually decreased symptoms below the threshold for PTSD diagnosis. It made a large difference in reducing PTSD symptoms."

According to Scripps, Healing Touch is aimed at eliciting the participant's own healing response by restoring and balancing the human biofield -- or the energy created by the body. It helps patients to relax byreducing pain and anxiety.

Guided imagery uses visualization techniques, prompted by using a compact disc, to accomplish the same tasks, the study's authors said.

Dr. Wayne Jonas, president and chief executive officer of the Samueli Institute, an Alexandria, Va.-based organization that helped with data analysis, said returning troops are looking for alternative treatments that don't involve medications.

The study was funded by The Taylor Family Foundation.

Copyright 2012 by City News Service. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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Scripps study on PTSD symptoms released

New therapy helps Marines suffering combat stress

3:50 p.m. PDT, September 24, 2012

SAN DIEGO -- Symptoms of Post-Traumatic Stress Disorder are eased by a combination of guided imagery and a specific type of therapy called "Healing Touch,'' the Scripps Center for Integrative Medicine announced Monday.

Results of a study of 123 Marines who returned from deployment to Camp Pendleton between July 2008 and August 2010 were released in the September issue of the publication Military Medicine. Those selected were experiencing traumatic flashbacks, nightmares,emotional numbness, insomnia and other PTSD symptoms.

The 68 participants who went through six sessions over three weeks with Healing Touch and guided imagery fared much better than the 55 who received normal treatment, according to Scripps.

"Scores for PTSD symptoms decreased substantially, about 14 points and below the clinical cutoffs for PTSD,'' said Dr. Mimi Guarneri, a Center for Integrative Medicine founder. "This indicates that the intervention was not just statistically significant, but actually decreased symptoms below the threshold for PTSD diagnosis. It made a large difference in reducing PTSD symptoms.''

According to Scripps, Healing Touch is aimed at eliciting the participant's own healing response by restoring and balancing the human biofield -- or the energy created by the body. It helps patients to relax by reducing pain and anxiety.

Guided imagery uses visualization techniques, prompted by using a compact disc, to accomplish the same tasks, the study's authors said.

Dr. Wayne Jonas, president and chief executive officer of the Samueli Institute, an Alexandria, Va.-based organization that helped with data analysis, said returning troops are looking for alternative treatments that don't involve medications.

The study was funded by The Taylor Family Foundation.

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New therapy helps Marines suffering combat stress

New study shows PTSD symptoms reduced in combat-exposed military via integrative medicine

Public release date: 24-Sep-2012 [ | E-mail | Share ]

Contact: Keith Darce darce.keith@scrippshealth.org 858-678-7121 Scripps Health

SAN DIEGO (Sept. 24, 2012) Healing touch combined with guided imagery (HT+GI) provides significant clinical reductions in post-traumatic stress disorder (PTSD) symptoms for combat-exposed active duty military, according to a study released in the September issue of Military Medicine.

The report finds that patients receiving these complementary medicine interventions showed significant improvement in quality of life, as well as reduced depression and cynicism, compared to soldiers receiving treatment as usual alone.

The study, led by the Scripps Center for Integrative Medicine in San Diego, Calif., conducted a randomized controlled trial of returning active-duty Marines at Camp Pendleton, Calif. from July 2008 to August 2010. Participants were separated at random into two groups, one that received treatment as usual (TAU) for PTSD and another that received TAU as well as healing touch (HT), a practitioner-based treatment aimed at eliciting the participant's own healing response, with guided imagery (GI), a self-care therapy aimed at eliciting relaxation as well as enhancing trust and self-esteem.

Significant Improvements Reported

After six sessions within a three-week period with a Scripps practitioner, the HT+GI group reported a significant improvement in PTSD symptoms as a result of these combined complementary therapies.

The principal investigators and designers of the study are Dr. Mimi Guarneri and Rauni King, founders of the Scripps Center for Integrative Medicine. The Samueli Institute of Alexandria,Va., conducted blind data analysis and authored the manuscript.

"Scores for PTSD symptoms decreased substantially, about 14 points and below the clinical cutoffs for PTSD," said Dr. Guarneri. "This indicates that the intervention was not just statistically significant, but actually decreased symptoms below the threshold for PTSD diagnosis. It made a large difference in reducing PTSD symptoms."

Study Criteria

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New study shows PTSD symptoms reduced in combat-exposed military via integrative medicine

What is this thing called love? Mere chemical trickery

Kayt Sukel, contributor

In The Chemistry Between Us, neuroscientist Larry Young and journalist Brian Alexander examine the neurobiological roots of love

THERE is a reason most of us sigh into our drinks when Cole Porter croons, "What is this thing called love?" We understand his befuddlement all too well. (And let's face it: if a man about town like Porter couldn't figure out this whole love thing, what hope is there for the rest of us mere mortals?)

That's why it is encouraging to know that in the past two decades social neuroscientists have been diligently working to unravel the mysteries of love - including the phenomena of attraction, monogamy and the parent-child bond - using techniques such as brain imaging, genome-wide association studies and transgenic animal models. In The Chemistry Between Us, Larry Young, the director of Emory University's Center for Translational Social Neuroscience, and journalist Brian Alexander offer a novel take on many of those findings.

A few recent books, including my own, Dirty Minds, have chronicled love and sex-related efforts in neuroscience. One of the criticisms of many of these tomes is that they fail to take on the functional "why" questions - why monogamy exists at all, for example, or why some people are more prone to infidelity. In The Chemistry Between Us, Young and Alexander do not shy away from proposing some strong hypotheses about the ways our neurobiology shapes our behaviour when it comes to the "L" word.

Drawing on real stories as well as research, the authors take the reader on a fascinating journey through strip clubs, Romanian orphanages and labs where rodents are regularly stimulated with lubed paintbrushes. These myriad adventures provide a great context for the science - and cleverly illustrate all the ways in which love and sex can make changes to our brain chemistry.

While those who closely follow the latest neurobiological research concerning love and sex might not find many new studies in this mix, they will find a rather unique interpretation of how they all fit together.

Young, who is arguably one of most prolific researchers in the social neuroscience field, plants his flag firmly: he argues that love is truly an addiction and one to which none of us are immune. He takes a reductionist approach, focusing on molecules like dopamine, oxytocin and vasopressin, and examining how these chemicals exploit ancient neurobiological circuits.

Some may feel uncomfortable when Young and Alexander claim that sex tricks women into "babysitting" the men they love - nurturing them as they would their own infants, thanks to the goodly amounts of oxytocin released during the sex act by men hitting the cervix with their large penises and playing with their breasts. Sceptics probably won't feel much better when Young and Alexander postulate that vasopressin helps men see their female partners as simply extensions of their territory.

Still, the authors don't back down. "Many would like to believe that such notions are outdated stereotypes," they write. "They're not. We can fake it, but nature gets the last word." Not overly concerned with political correctness, Young and Alexander even go so far as to extend these hypotheses to touch on modern issues like marriage equality and single motherhood.

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What is this thing called love? Mere chemical trickery

UCSB Professors Receive National Chemistry Awards

Two UC Santa Barbara professors have been named recipients of the American Chemical Societys 2013 national awards for professionaladvancement. Peter C. Ford, professor in the Department of Chemistry and Biochemistry, and Craig J. Hawker, also a professor in the Department of chemistry and Biochemistry,professor of materials, and director of the Materials Research Laboratory, have been named among the 64 award winners from across the country

In only one other year, 1996, did UCSB have more than one winner of theAmerican Chemical Society (ACS) awards. The awards will be presented at the nationalACS meeting in New Orleans in April.Ford is the recipient of the ACS Award for Distinguished Service in the Advancement of Inorganic Chemistry. This award recognizes individuals who haveadvanced inorganic chemistry by significant service, in addition to performingoutstanding research. It is sponsored by StremChemicals.

I am of course very pleased and honored to have received this award from my colleagues in the American Chemical Society, saidFord.

Since this is largely in recognition of the body of work generated by my graduate and postdoctoral students and collaborators over my tenure at UCSB, I consider it an award to my research group collectively as well as another testament to the high regard in which this campus is nowheld. I am proud to be aGaucho.

Hawker has been named recipient of the ACS Award in Polymer Chemistry. Thecitation states that Hawker was nominated for transforming the field of polymer chemistry through the clever adaptation of synthetic organic chemistry concepts and theadvancement of macromolecular engineering. ExxonMobil Chemical Company sponsored thisaward.

I am thrilled with the award and the recognition that it brings to my students, collaborators, and co-workers, as well as to the unique research environment at UCSB, said Hawker. The sustained success of cross-disciplinary research has been a key driver in reinforcing UCSBs international standing in the materials chemistry arena. I am grateful for the enormous benefits that this proud tradition has bought to myresearch.

Ford joined the faculty at UCSB in 1967 after earning his Ph.D. at Yale and completing a National Science Foundation postdoctoral fellowship with Nobel laureateHenry Taube at Stanford University. He is a Fellow of the American Association for theAdvancement of Science and was a Senior Fulbright Fellow. His awards include a Dreyfus Foundation Teacher-Scholar Award in 1972; the Alexander von Humboldt Foundation Senior U.S. Scientist Award in 1992; the Richard C. Tolman Medal of theACS in 1993; and the Inter-American Photochemical Society Award in Photochemistry in2008.

Hawker received his Ph.D. from the University of Cambridge, and then completeda postdoctoral fellowship with Jean M. J. Frchet at Cornell. In 2004, he moved from theIBM Almaden Research Center to join the faculty at UCSB. Some of his recent awardsinclude the 2012 Centenary prize from the Royal Society of Chemistry; the 2011 Arthur C. Cope Scholar from the American Chemical Society; and the 2008 DSM PerformanceMaterials Award from the International Union of Pure and Applied Chemistry. In 2010,he was named a Fellow of the RoyalSociety.

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UCSB Professors Receive National Chemistry Awards

BIO Announces Therapeutic Workshops for 11th Annual BIO Investor Forum

WASHINGTON--(BUSINESS WIRE)--

The Biotechnology Industry Organization (BIO) announces Therapeutic Workshops on Cancer stem cell therapy, kinase drugs, and ultra rare diseases planned for the upcoming BIO Investor Forum. Hosted by BIO, the 11th annual event will take place at the Palace Hotel on October 9-10 in San Francisco, Calif.

This years Therapeutic Workshops will address some of the most exciting therapeutic advances for the biotech industry. We have worked very closely with this years esteemed Advisory Committee to identify topics that will engage investors and industry alike, said Alan Eisenberg, executive vice president, Emerging Companies & Business Developmentat BIO.

Therapeutic Workshops will feature senior-level industry executives, scientific officers and leading clinical experts that represent innovative investment opportunities in the biotech industry.

Therapeutic Workshops include:

The BIO Investor Forum features public and venture-stage company presentations, expert-led, business roundtables, one-on-one investor meetings and networking opportunities.

To learn more about the BIO Investor Forum, including registration and program information, please visit here. Advance media registration is available here. Registration is complimentary for credentialed members of the media and qualified investors.

BIO is pleased to recognize the leadership provided by the BIO Investor Forum Conference sponsors including Supporting Bank Stifel, Nicolaus & Company. BIO Double Helix and Helix Sponsors include Abbott Biotech Ventures, Amgen Ventures, Baxter Ventures, J&J Development Corporation, MedImmune Ventures, GlaxoSmithKline, Merck and Pfizer.

About BIO

BIO represents more than 1,100 biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 other nations. BIO members are involved in the research and development of innovative healthcare, agricultural, industrial and environmental biotechnology products. BIO also produces the BIO International Convention, the worlds largest gathering of the biotechnology industry, along with industry-leading investor and partnering meetings held around the world. BIO produces BIOtechNOW, an online portal and monthly newsletter chronicling innovations transforming our world. Subscribe to BIOtechNOW.

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BIO Announces Therapeutic Workshops for 11th Annual BIO Investor Forum

Ovizio And Applikon Biotechnology Sign Long Term Marketing And Distribution Agreement

Ovizio Imaging Systems and Applikon Biotechnology jointly announce today the signing of a long term worldwide marketing and distribution agreement for an innovative device using a proprietary imaging technology in microscopy.

Applikon will market worldwide an innovative and integrated solution, developed by Ovizio, that combines 4D microscopic imaging with the Applikon bioreactor systems. This new device will offer automated on-line information on cell density, cell viability and morphologic state of the cells.

Applikon and Ovizio have a common vision of the potential of optical image analysis in bioprocessing said Erik Kakes, commercial director of Applikon Biotechnology. "We feel that using optical 4D image analysis for determination of biomass concentration and viability is only the first step in applying this revolutionary technology to the bioprocess industry", he added.

We are absolutely delighted to partner with a company having such an in-depth knowledge of the market and strong reputation within the Bioprocess industry, said Philip Mathuis, CEO of Ovizio. We believe that quantitative imaging as a new Process Analytical Technology (PAT) applied to on-line bioreactor monitoring will allow Biopharma customers to improve process knowledge, quality and productivity in their R&D, Pilot and Production environments.

The new device will be jointly presented at the next Het Instrument Amsterdam, exhibition on 26 September 2012.

About Ovizio Imaging Systems NV/SA Ovizio is a spin-off company of the Universit Libre de Bruxelles (ULB). The company designs, develops and markets 4-D quantitative imaging systems and sensors based on patented Digital Holographic Microscopy with a primary focus on the Life Science Research, Biotechnology and Bioprocessing industry..

Ovizios platform technology unifies real-time quantitative imaging with speed and a label-free, non-invasive approach. Our advanced devices generate high quality holographic images ideal for studying dynamic phenomena, breaking the barriers between the traditional speed of flow cytometry and the resolution of classical microscopy.

Ovizio is a privately held company situated in Brussels, Belgium. For more information, visit http://www.ovizio.com.

SOURCE: Applikon Biotechnology

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Ovizio And Applikon Biotechnology Sign Long Term Marketing And Distribution Agreement

Research of alligator blood could one day help humans

Researchers at McNeese State University believe alligators could hold thekey to healing humans.

At the helm of the study is Dr. Mark Merchant, professor of biochemistry.

Merchant saidhis interest with gators began at an early age.

"I grew up in the marshes of Southwest Louisiana and Southeast Texas hunting and fishing and I am still in the marsh a lot pursuing those activities. I've been around alligators most of my life," Merchant said.

Merchant said he realized a long time ago that there was something special about the immune systems of theseprehistoric animals.

"Alligators and crocodiles are very territorial and they fight andat times, inflict great injury on one another butthe fact is it seems they heal rather rapidly despite the fact they live in an environment wherethere are lots of potentially infectious microbes such asbacteria and fungi and things that can infect these massive wounds," Merchant said.

When his research began 11 years ago, Merchantwas able to prove the blood of alligators could kill pathogens. Since then, he has learned more howalligator blood kills bacteria, fungi and viruses, specifically white blood cells.

"What we have found in the last four or five years is that the white blood cells from alligators can and other crocodilians around the world make these tiny peptides that have tremendous antibacterial and antifungal activity," explained Merchant. "We have just recently isolated the small peptides or proteins and are working to determine the exact structure. So we think we potentially may have not only a new antibiotic, but a whole new class of antibiotics for human and veterinary use."

Merchantsaid there is still a lot of researchbeforethe antibioticcan be produced inlabs.

"It could be tomorrow. It could be next month or it could be in 10 years. I hope it is sooner rather than later," he said.

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Research of alligator blood could one day help humans

School nutrition law takes bite out of portion sizes

The new federal law governing school nutrition means smaller slices of pizza and possibly higher prices for students in the Central Bucks School District.

To comply with the Healthy, Hunger-Free Kids Act of 2010, pizza slices are now 2 inches smaller, said Alicia Kent, senior director at Aramark, which provides food service to the districts schools.

Aramark officials reviewed the new law and its impact during a school board meeting on Monday evening.

The 14-inch pizza slices are necessary, Kent said, to comply with the maximum calorie and grain restrictions in the new law, which went into effect this year and will be fully phased in over three years.

In addition, she said, if a student fails to select a fruit or vegetable as part of his or her meal, the cost will be higher than a student who does make that part of the meal. Thus, a student selecting a slice of pizza and milk will pay more than a student purchasing pizza, an apple and milk.

If they dont take a fruit or vegetable they are charged a la cart pricing, Kent said. Theres a little bit of sticker shock when they are coming through the line and learning what the new requirements are.

There may be a monetary impact on the district as well, she said, noting that the district will not receive reimbursement for student meals that do not meet the new U.S. Department of Agriculture requirements.

These are really significant changes of what the students are allowed to eat, she said.

Among the changes required are the use of only fat-free flavored milk, decreased sodium levels and at least half the grains offered must be whole grain. It also requires different nutrient levels for different age groups.

The new rules will be challenging for students, she said, and require education of students and parents.

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School nutrition law takes bite out of portion sizes

Tufts University Offers Master's In Nutrition For Distance Learners

Newswise The Friedman School of Nutrition Science and Policy at Tufts University today announced a Master of Nutrition in Science and Policy (MNSP) degree program that combines intensive on-campus residencies in Boston with online learning. The blended learning program will enroll its first cohort of students in the fall of 2013. The Friedman Schools blended learning degree is the only masters degree in nutrition in the United States that combines week-long residencies on campus with online learning.

The blended learning format will allow students from around the world to continue living and working where they choose while they study at one of the premier research universities in the United States, said Robin Kanarek Ph.D., interim dean of the Friedman School of Nutrition Science and Policy. Nutrition is a vitally important field, and the Friedman School is committed to educating and training future leaders who can create new knowledge and apply and disseminate evidence-based information.

For approximately one week each semester, students and Tufts faculty will meet at the Friedman School in Boston for a residency period that includes interactive coursework, lectures, seminars and collaboration among students of diverse backgrounds. These on-campus residencies will facilitate hands-on learning and in-person meetings among students and between students and faculty. Following each residency session, the coursework continues in a highly facilitated online environment, building on the knowledge and relationships developed on campus. Students may attend the program full-time or part-time.

The combination of online and on-campus learning was first developed by the Friedman School to bring graduate-level nutrition education to students in the United Arab Emirates and surrounding countries. The experience our faculty members have acquired in blended learning has given us a unique ability to educate students wherever they live and advance the schools mission of improving the wellbeing of persons, communities and populations worldwide, said Lynne Ausman, D.Sc., R.D., MSNP program director and Saqr Bin Mohammed Al Qasimi Professor in International Nutrition at the Friedman School.

The Master of Nutrition Science degree is part of the Friedman Schools fully accredited academic offerings and is taught by faculty from the schools campus in Boston, Massachusetts. Admissions, curriculum, and tuition information, as well as a video and downloadable brochure, are available online at http://nutrition.tufts.edu/mnsp.

The Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University is the only independent school of nutrition in the United States. The schools centers, which focus on questions relating to famine, hunger, poverty, and communications, are renowned for the application of scientific research to national and international policy. The Schools web site is http://nutrition.tufts.edu

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Tufts University Offers Master's In Nutrition For Distance Learners

New online, open access journal focuses on microbial genome announcements

Public release date: 24-Sep-2012 [ | E-mail | Share ]

Contact: Jim Sliwa jsliwa@asmusa.org 202-942-9297 American Society for Microbiology

The American Society for Microbiology is launching a new online-only, open access journal, Genome Announcements, which will focus on reports of microbial genome sequences. Genome Announcements will begin publishing in January 2013.

"The revolution in high-speed, low-cost, and high-throughput parallel sequencing technology has changed the way we think about whole-genome sequencing and sequences. Identification of novel bacteria and viruses by sequencing entire genomes of isolates from normal and diseased tissue or the environment is now routine," says Tom Shenk of Princeton University, Chair of the ASM Publications Board.

Although sequence data typically are deposited in GenBank or other shared databases, the rationale for sequencing a particular organism and the detailed methodologies and protocols used often are not readily available.

Since 2007, the ASM's Journal of Bacteriology has published Genome Announcements, brief reports stating that the genome of a particular organism has been sequenced and deposited which provide a citable record of the corresponding GenBank submission. Two other ASM journals, the Journal of Virology and Eukaryotic Cell, joined the Journal of Bacteriology in accepting Genome Announcements in 2011 as a simple, rapid way for authors to inform their communities about completion of new sequencing projects.

"The exponential increase in submissions and the usage of Genome Announcements has confirmed the value and service they bring to the scientific community. As a result, ASM will now publish all Genome Announcements in a single, dedicated, online-only, open-access journal starting January 2013," says Phil Matsumura of the University of Illinois at Chicago, editor of the new journal.

Eukaryotic Cell, Journal of Bacteriology, and Journal of Virology will cease publishing Genome Announcements with the last issues of the 2012 volume year.

Any Genome Announcement manuscript accepted for publication in these three journals by 30 September 2012 will be published in 2012. Authors whose submissions are accepted on or after 1 October 2012 will have the option to transfer their submission to Genome Announcements.

Manuscripts submitted to Genome Announcements must include an abstract, an acknowledgments section indicating the source of support for the work, and a nucleotide sequence accession number. Manuscripts are limited to 500 words (exclusive of the abstract and acknowledgments), and no text headings should be used except for "References." Sequences must be made publicly available before a submission will be considered for publication, and the nucleotide sequence accession number(s) must be provided in a separate paragraph at the end of the text. Manuscripts may not include figures, tables, or supplemental material used to present data or analysis. However, multiple related sequences and their accompanying accession numbers and URL may be presented in tabular form. Publication of Sequence Read Archives (SRAs) is not permitted.

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New online, open access journal focuses on microbial genome announcements

Could viruses be used to treat acne?

Public release date: 25-Sep-2012 [ | E-mail | Share ]

Contact: Jim Sliwa jsliwa@asmusa.org 202-942-9297 American Society for Microbiology

Scientists have isolated and studied the genomes of 11 viruses, known as phage, that can infect and kill the acne-causing bacterium Propionibacterium acnes, potentially paving the way for topical therapies that use viruses or viral products to treat this vexing skin condition. Their results are reported in the September 25 issue of mBio, the online open-access journal of the American Society for Microbiology.

"There are two fairly obvious potential directions that could exploit this kind of research," says Graham Hatfull of the University of Pittsburgh, an author of the study. "The first is the possibility of using the phages directly as a therapy for acne. The second is the opportunity to use phage-derived components for their activities."

P. acnes is a normal resident on human skin, but its numbers increase substantially at puberty, eliciting an inflammatory response that can lead to acne. Although antibiotics can be effective in treating acne, antibiotic-resistant strains of P. acnes have emerged, highlighting the need for better therapies.

Hatfull and his colleagues at the University of Pittsburgh along with scientists from the University of California, Los Angeles, isolated phages and P. acnes bacteria from human volunteers with and without acne, then sequenced the phages' genomes. What they found in those genomes was surprising. The phages were all remarkably similar, sharing more than 85% of their DNA, an unheard of level of similarity among viruses, which usually exhibit a great deal of diversity. This lack of genetic diversity suggests that resistance to phage-based antimicrobial therapy is less likely to develop, they say.

All of the phages carry a gene that makes a protein called endolysin, an enzyme that is thought to break down bacterial cell walls and kill the bacteria. Enzymes like this are used in other applications, says Hatfull, suggesting that endolysin from these phages might also be useful as a topical anti-acne therapeutic. "This work has given us very useful information about the diversity of that set of enzymes and helps pave the way for thinking about potential applications," he says.

From here, Hatfull says, research with these phages will explore how they might be used therapeutically, but phages like these can also provide useful tools, like genes and enzymes, that can be used to manipulate and understand the bacteria they infect. "The information derived from these phages helps contribute toward those kinds of genetic tools," says Hatfull.

###

mBio is an open access online journal published by the American Society for Microbiology to make microbiology research broadly accessible. The focus of the journal is on rapid publication of cutting-edge research spanning the entire spectrum of microbiology and related fields. It can be found online at http://mBio.asm.org.

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Defense claims new DNA evidence in Dechaine case

1:00 AM

By Ann S. Kim akim@mainetoday.com Staff Writer

PORTLAND -- Further testing of items from the 1988 murder of 12-year-old Sarah Cherry has yielded new DNA, but it's too early to know what the implications are for her convicted killer, Dennis Dechaine.

Dechaine is in the midst of a long-running attempt to win a new trial. To do so, he must convince a judge that a jury would not have convicted him had they known about DNA evidence found on Cherry's thumbnail.

The latest development in Dechaine's bid is the discovery of male DNA on the scarf that was used to strangle the girl, as well as her T-shirt and bra. The items had been tested previously in the case but were retested this summer using a scraping method that had not been employed. That DNA came from the same male, according to a report by Orchard Cellmark, the Dallas-based firm that performed the analysis.

The DNA has not yet been compared to any others samples, including DNA from Dechaine, individuals who worked on the investigation or the felons in a state database. A fresh blood sample was recently taken from Dechaine for comparison purposes.

"The thing we're hoping for -- of course, we could have it backfire on us -- is that this could prove it's not Dennis Dechaine," said Steve Peterson, Dechaine's court-appointed lawyer.

Dechaine, 54, is serving a life sentence for the murder of Cherry, a Bowdoin Central School student who was kidnapped while babysitting on July 6, 1988. He maintains he did not commit the crime. His defense contends the unidentified male DNA from a nail clipped from Sarah Cherry during her autopsy points to another suspect.

The prosecutor, Deputy Attorney General William Stokes, has argued that the state and jurors who convicted Dechaine already know who killed Cherry. He has described the thumbnail DNA as meaningless.

"We don't know what it means," he said Monday of the latest DNA testing.

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Defense claims new DNA evidence in Dechaine case

Posted in DNA

DNA in 1980 Maine murder case shown to match defendant

Posted: 10:50 PM Updated: 12:44 AM Samples from the body of Rita St. Peter match the DNA profile of Jay Mercier, an expert says.

By DOUG HARLOW/Morning Sentinel

SKOWHEGAN DNA samples taken from the body of Rita St. Peter in 1980 match the DNA profile of Jay Mercier of Industry, the man who is charged with sexually assaulting and killing her, a state witness said in court Monday.

click image to enlarge

Murder defendant Jay Mercier looks around the courtroom on Thursday, Sept. 20, 2012 during his trial in Somerset County Superior Court for the death of Rita St. Peter 32 years ago..

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Rita St. Peter in an undated file photo. She was 20 at the time of her death when her body was found off the Campground Road in Anson on July 5, 1980.

"Unless you have an identical twin, there is no one else in the world with your DNA," Kathy MacMillan, a forensic DNA analyst with the state police crime lab, told the jury in Somerset County Superior Court.

MacMillan said the possibility that DNA samples taken from St. Peter's body didn't come from Mercier is one in a trillion.

MacMillan's testimony came on the third day of the murder trial for Mercier, who was 25 when St. Peter's body was found off Campground Road in Anson on July 5, 1980.

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DNA in 1980 Maine murder case shown to match defendant

Posted in DNA

Former Alabama professor gets life in prison

Former Alabama biology professorAmy Bishop avoided a death sentence by pleaded guilty to killing three colleagues and wounding three others in a 2010 shooting rampage at the University of Alabama at Huntsville.

A former Alabama biology professor who pleaded guilty to killing three colleagues and wounding three others in a 2010 shooting rampage was sentenced to life in prison without parole on Monday after a jury convicted her in a shortened trial.

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Amy Bishop, avoided a death sentence by admitting earlier this month to gunning down her colleagues during a biology department staff meeting at the University of Alabama at Huntsville.

Alabama law requires a jury to decide the punishment and confirm a guilty plea for a capital murder charge.

Bishop's defense attorneys did not contest the facts of the case during the abbreviated proceedings on Monday.

"She has admitted she did these terrible things," defense attorney Robert Tuten said in his opening statement.

Bishop, a Harvard-trained biologist and mother of four, was accused of shooting her colleagues execution-style in February 2010. Colleagues believed Bishop was angry that the school had denied her tenure.

The trial on Monday took less than two hours and featured only two witnesses. One was Bishop's former colleague Debra Moriarity, who recalled how she tried to take Bishop down after the woman started firing during the meeting.

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Former Alabama professor gets life in prison

The Cancer Genome Atlas (TCGA) Study Supports Power of Subtyping Breast Cancer by PAM50

SEATTLE--(BUSINESS WIRE)--

On September 23, researchers published online in the journal Nature a study of the molecular biology of breast cancer, using the intrinsic subtypes as defined by the PAM50 gene signature as an organizing framework for analyzing genomic and proteomic aberrations. This landmark study both underscores the emergence of the intrinsic subtypes as a powerful taxonomy of breast cancer in research, and PAM50s role as the gold standard for categorizing breast cancer by subtype.

This study, titled Comprehensive molecular portraits of human breast tumours, represents the most complete description of breast cancer biology to date. The study was an outcome of The Cancer Genome Atlas (TCGA) Initiative, a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies. The study involved the analysis of tissue from 800 breast cancer tumors by a total of six technology platforms, covering genomics, epigenetics, and proteomics.

Intrinsic subtype by PAM50 was used as a primary organizing framework for the analysis and presentation of the data. The research concluded that diverse genetic and epigenetic alterations converge phenotypically into the four main breast cancer subtypes defined by PAM50 Luminal A, Luminal B, HER2-enriched, and Basal-like.

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and developer of molecular diagnostics, is developing a PAM50-based in vitro diagnostic test for breast cancer. NanoString announced in December 2010 that it had secured an exclusive worldwide license for the PAM50 gene signature from Bioclassifier, LLC to develop in vitro diagnostic and research products for breast cancer on its nCounter Analysis System.

This research advances our understanding of the molecular architecture of breast cancer, and reinforces the emergence of intrinsic subtypes by PAM50 as a powerful description of breast cancer biology, said NanoString President & CEO Brad Gray. We congratulate the authors on this seminal contribution to our understanding of breast cancer, and look forward to the day when analysis of breast cancer tumors by PAM50 will be available to patients worldwide.

The nCounter Analysis System is a fully automated, multi-application digital detection and counting system with a very simple workflow currently intended for research use only. The nCounter system has been employed in basic and translational research since it was first introduced in 2008. NanoString provides assays for gene expression, miRNA analysis and copy number variation.

About NanoString Technologies, Inc.

NanoString Technologies is a privately held provider of life science tools for translational research and developer of molecular diagnostics. The companys nCounter Analysis System is the first and only technology platform to deliver highly multiplexed, direct profiling of individual molecules in a single reaction without amplification. The nCounter Analysis System offers a cost-effective way to easily profile hundreds of gene transcripts, copy number variations, or miRNAs simultaneously with high sensitivity and precision. The companys technology enables a wide variety of basic research and translational medicine applications, including biomarker discovery and validation. NanoString is also developing the technology for use in molecular diagnostics.

The NanoString Technologies design logo, NanoString, NanoString Technologies and nCounter are registered trademarks of NanoString Technologies, Inc. All other trademarks are property of their respective owners.

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The Cancer Genome Atlas (TCGA) Study Supports Power of Subtyping Breast Cancer by PAM50

Research of alligator blood could one day help humans

Researchers at McNeese State University believe alligators could hold thekey to healing humans.

At the helm of the study is Dr. Mark Merchant, professor of biochemistry.

Merchant saidhis interest with gators began at an early age.

"I grew up in the marshes of Southwest Louisiana and Southeast Texas hunting and fishing and I am still in the marsh a lot pursuing those activities. I've been around alligators most of my life," Merchant said.

Merchant said he realized a long time ago that there was something special about the immune systems of theseprehistoric animals.

"Alligators and crocodiles are very territorial and they fight andat times, inflict great injury on one another butthe fact is it seems they heal rather rapidly despite the fact they live in an environment wherethere are lots of potentially infectious microbes such asbacteria and fungi and things that can infect these massive wounds," Merchant said.

When his research began 11 years ago, Merchantwas able to prove the blood of alligators could kill pathogens. Since then, he has learned more howalligator blood kills bacteria, fungi and viruses, specifically white blood cells.

"What we have found in the last four or five years is that the white blood cells from alligators can and other crocodilians around the world make these tiny peptides that have tremendous antibacterial and antifungal activity," explained Merchant. "We have just recently isolated the small peptides or proteins and are working to determine the exact structure. So we think we potentially may have not only a new antibiotic, but a whole new class of antibiotics for human and veterinary use."

Merchantsaid there is still a lot of researchbeforethe antibioticcan be produced inlabs.

"It could be tomorrow. It could be next month or it could be in 10 years. I hope it is sooner rather than later," he said.

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Research of alligator blood could one day help humans

Stem cells revolutionizing veterinary medicine

(WGBA/NBC) - It is a story that gives hope to pet owners all over the country stem cell therapy for animals suffering from problems like arthritis or hip displaysia.

Stem cells are taken out of the dog's fatty tissue are harvested then injected into problem areas leaving the dogs completely healed.

"We couldn't take him on walks, he just laid around a lot," said Keith Nosowiak, Deniro's owner.

"We'd hear whimpering overnight, she'd take a few steps and she would sit down," said Luther Kortbein, Shadow's owner.

Until two months ago, Deniro suffered from severe arthritis, Shadow from hip displaysia.

Deniro's owner thought he may even have to put his German shepherd down.

"We felt we had a decision to make with his quality of life and being in pain we didn't want him to be in pain," Noskowiak said.

Shadow's owner was willing to try anything to cure her.

"Whatever the cost needed to get this done we were willing to do," Kortbein said.

Then Packerland Veterinary Center offered them stem cell therapy by using the dogs own stem cells and then injecting them back into the bloodstream joints.

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Stem cells revolutionizing veterinary medicine