By Carina Storrs HealthDay Reporter

MONDAY, Aug. 27 (HealthDay News) -- With the U.S. presidential campaign season heating up and Election Day drawing nearer, political science experts are saying that campaigns could one day benefit from having a deeper understanding of voters, all the way down to their DNA.

"Since about 2005, there has been a turning of the tide that genes can influence political traits," said Peter Hatemi, an associate professor of political science, microbiology and biochemistry at Pennsylvania State University.

"Most social scientists had viewed the world as a blank slate, whatever your family is, whatever you run into and your experiences, is how you develop your attitudes," he added.

Research into the genetic underpinnings of political views has grown significantly in the past eight years, Hatemi said. His comprehensive review of previous research on the role genes play in attitudes, ideologies and voting behavior, is co-authored by Rose McDermott, a professor of political science at Brown University, and appears online Aug. 27 in Trends in Genetics.

Political scientists have borrowed pages from the geneticists' book of techniques for studying medicine and psychology, but it may be how political scientists are using these approaches that will have the biggest impact on public health.

"The world revolves around politics, it doesn't revolve around schizophrenia. It's important to study because the biggest determinant of public health is going to be politics," Hatemi said.

One technique in particular involves studying identical and fraternal twins. Researchers can compare how often identical twins, who share all of their genes, and fraternal twins, who share half their genes on average, give the same answers to political questions to gauge how big of a role genes play in different categories.

Hatemi and McDermott reviewed previous twin studies and reported that about half of the variation in political traits could be explained by genetics, the other half by upbringing and environment.

Categories such as political knowledge and liberal versus conservative ideology were more likely to be influenced by genetics, whereas political party identification was strongly affected by upbringing, the researchers said.

More:
Could Your Genes Influence How You Vote?

A tiny resonating beam, just 10 millionths of a meter in length, can measure the mass of a molecule or nanoparticle in real time

By John Matson

WEIGHTY MATTERS: The diagonal beam in this image can detect the presence of single molecules and determine their mass. Image: Caltech/Scott Kelber and Michael Roukes

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Dieters and exercise buffs might feel better about their progress if they tracked their weight loss in daltons. Even a short jog can help you shed a few septillion daltons, a unit of mass often used in biochemistry that is equivalent to the atomic mass unit. (Of course, no weight-conscious individual would want to know their full weight in this unitthe average American male weighs approximately 5 X 1028 daltons.)

Even the megadalton, or one million daltons, is a tiny unit of measurea gold particle five nanometers across weighs in at just a few megadaltons. (One nanometer is a billionth of a meter.) But researchers at the California Institute of Technology and CEALeti, a government-funded research organization in Grenoble, France, have built a scale that weighs single objects even lighter than a megadalton, including nanoparticles and human antibody molecules. The device is the first of its kind to determine the masses of individual molecules and nanoparticles in real time, the researchers reported in a study published online August 26 in Nature Nanotechnology. (Scientific American is part of Nature Publishing Group.)

The heart of the device is a nanoelectromechanical resonatora tiny beam of silicon vibrating at two tones simultaneously. "It's like vibrating a guitar string at the fundamental and a harmonic," says study co-author Michael Roukes, a Caltech physicist. "We're continuously strumming it with an electrostatic excitation." The beam runs diagonally across the photo (above); it measures 10 microns long and 300 nanometers wide. (A micron is one millionth of a meter.)

Tiny arms connecting the ends of the beam to the rest of the device convert the resonator's vibrations into an electrical signal via a phenomenon known as the piezoresistive effect. "The smallest pieces there are flexed slightly, and when they're flexed their resistance changes," Roukes says. "And so we can read out the motion as a change in resistance." A single molecule landing on the beam shifts the frequency of the two tones downward, and from the accompanying change in resistance the researchers can deduce both the mass of the particle and where it landed along the beam.

The device's sensitivity to single molecules allowed the researchers to perform mass spectroscopyidentifying the various particles in a mixture by their masseson collections of gold nanoparticles five and 10 nanometers in diameter, as well as on the antibody molecule immunoglobulin M, which weighs just under one megadalton. (The natural molecules proved much more consistent in their construction than did the man-made nanoparticles, whose masses fluctuated by a factor of five or so from particle to particle.)

Excerpt from:
Scaled-Down: New Nano Device Can Weigh Single Molecules

29.08.2012 - (idw) Ruhr-Universitt Bochum

First place in an EU competitive call on Unconventional Computing was awarded to a collaborative proposal coordinated by Prof. John McCaskill from the RUB Faculty of Chemistry and Biochemistry. The project MICREAgents plans to build autonomous self-assembling electronic microreagents that are almost as small as cells. They will exchange chemical and electronic information to jointly direct complex chemical reactions and analyses in the solutions they are poured into. The EU supports the project within the FP7 programme with 3.4 million Euros for three years. Turning chemistry inside-out Self-assembling smart microscopic reagents to pioneer pourable electronics 3.4 million Euros from EU programme for international research project

First place in an EU competitive call on Unconventional Computing was awarded to a collaborative proposal coordinated by Prof. John McCaskill from the RUB Faculty of Chemistry and Biochemistry. The project MICREAgents plans to build autonomous self-assembling electronic microreagents that are almost as small as cells. They will exchange chemical and electronic information to jointly direct complex chemical reactions and analyses in the solutions they are poured into. This is a form of embedded computation to compute is to construct in which for example the output is a particular catalyst or coating needed in the (input) local chemical environment. The EU supports the project within the FP7 programme with 3.4 million Euros for three years. Four research groups at RUB will join forces with top teams across Europe, from Israel and New Zealand.

Self-assembling electronic agents

In order to create this programmable microscale electronic chemistry, MICREAgents (Microscopic Chemically Reactive Electronic Agents) will contain electronic circuits on 3D microchips, called lablets. The lablets have a diameter of less than 100 m and self-assemble in pairs or like dominos to enclose transient reaction compartments. They can selectively concentrate, process, and release chemicals into the surrounding solution, under local electronic control, in a similar way to which the genetic information in cells controls local chemical processes. The reversible pairwise association allows the lablets to transfer information from one to another.

Translating electronic signals into chemical processes

The lablet devices will integrate transistors, supercapacitors, energy transducers, sensors and actuators, and will translate electronic signals into constructive chemical processing as well as record the results of this processing. Instead of making chemical reactors to contain chemicals, the smart MICREAgents will be poured into chemical mixtures, to organize the chemistry from within. Ultimately, such microreactors, like cells in the bloodstream, will open up the possibility of controlling complex chemistry from the inside out.

The self-assembling smart micro reactors can be programmed for molecular amplification and other chemical processing pathways that start from complex mixtures, concentrate and purify chemicals, perform reactions in programmed cascades, sense reaction completion, and transport and release products to defined locations. MICREAgents represent a novel form of computation intertwined with construction. By embracing self-assembly and evolution, they are a step towards a robust and evolvable realization of John von Neumanns universal construction machine vision. Although these nanoscale structures will soon be sufficiently complex to allow self-replication of their chemical and electronic information, they will not present a proliferative threat to the environment, because they depend for their function on the electronic circuit layer that is fabricated as part of their substrate.

RUB collaborators

For the project, Prof. Dr. John S. McCaskill (Microsystems Chemistry and Biological Information Technology) collaborates with Prof. Dr. Gnter von Kiedrowski (Bioorganic Chemistry), Prof. Dr. Jrgen Oehm (Analog Integrated Circuits) and Dr. Pierre Mayr (Integrated Digital Circuits). McCaskills and von Kiedrowskis labs at RUB have already joined forces in previous European Projects forging a path towards artificial cells. The ECCell project, for example, that finished in February this year, has laid the foundation for an electronic chemical cell. There, the electronics and microfluidics were exterior to the chemistry: in MICREAgents this is being turned inside out.

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Project MICREAgents: self-assembling smart microscopic reagents to pioneer pourable electronics