Monthly Archives: June 2012

Alternative Medicine Tyler TX – From Sissy’s Desk @ Integrative Medicine of East Texas.mp4 – Video

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01-06-2012 09:05 Integrative Medicine of East Texas is an alternative medicine and holistic healing clinic that specializes in affordable primary care, bio-identical hormone therapy, medical weight loss, prolotherapy pain management solutions and chelation therapy in Tyler, TX. Contact us today at 903-730-6727. Alternative Medicine Tyler TX Integrative Medicine of East Texas 967 Pruitt Place Tyler, TX 75703 (903) 730-6727

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Alternative Medicine Tyler TX - From Sissy's Desk @ Integrative Medicine of East Texas.mp4 - Video

Around Iowa State University: June 3

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ISU proposes department name

Pending approval by the Iowa Board of Regents, Iowa State Universitys Department of Biochemistry, Biophysics and Molecular Biology will be named in honor of the Roy J. Carver Charitable Trust, in recognition of gifts and commitments to the department totaling more than $12.3 million.

This support includes a $7.5 million commitment announced Thursday to support strategic research initiatives in biomolecular structure.

Also known as structural biology, this scientific field seeks to better understand basic biomolecular function, which can hold the key to unlocking important new discoveries in wide-ranging areas important to human, plant and animal life.

With the regents approval, the new name will be the Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology.

ISU grads give scholarships

Benches, plaques, art, fountains these are typical class gifts. Tangible things you can sit on, gaze upon, drink from.

Cognizant of the growing financial pressures on college students, ISUs class of 2012 opted to leave something different to the alma mater. The class set up an endowment that will fund scholarships for upperclassmen.

Thus far, more than 600 recent graduates have pledged $45,400 to the scholarship fund.

Thats an average of $74 per graduate, said Sarah Johnson, a program manager in the ISU Foundation. And we expect the endowment to grow in the next couple of weeks as student fundraisers finish making contacts with the graduating seniors.

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Around Iowa State University: June 3

Anatomy of a rescue: Great training, cooperation and good luck combined to save three people whose plane crashed into …

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A miracle cellphone signal.

The perfect app.

More than 50 people slogging through the snowy wilderness in rugged Owyhee County on Memorial Day weekend.

Great training, cooperation and good luck combined to save three people whose plane crashed late May 26 into the mountains near the Idaho-Oregon border.

12:08 a.m. Send a search party, please

Dispatcher: Owyhee County 911, what is your emergency?

Caller: Hi, Im in an airplane, and I crashed and Im in the mountains.

Dispatcher: Where are you at, hon?

Caller: 29 miles east, west of Mountain Home, Idaho. I need you to send a search party, please ...

The 911 call was made by pilot Brian Browns daughter, Heather, about three hours after the crash. Her mothers cellphone had been tossed about, and it wasnt until it rang amid the wreckage that the Browns realized it worked on the remote mountain.

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Anatomy of a rescue: Great training, cooperation and good luck combined to save three people whose plane crashed into ...

Stem cell therapy for cornea treatment

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Hyderabad, June 2:

Picking stem cells from a patients body, sending it to a sophisticated laboratory to culture a tissue and then implanting it are pass.

A team of doctors at L.V. Prasad Eye Institute has used the tea bag or sprinkler approach to regenerate stem cells. The organisation has developed a lab-free technique that could be available off-the-shelf. This allows eye surgeons with usual facilities to perform the procedure.

The team, led by Dr Virender Singh Sangwan, used this technique to treat those who suffered chemical injuries, resulting in bleeding in the cornea.

Instead of sending stem cells to the lab for culture, the doctor picked the required number of stem cells around the cornea and sprinkled on the damaged area and then put a contact lens. In 15 days, he sees development of a good layer in the place of injured area, Prof. Balasubramanian, Head of Research at LVPEI, said.

A winner of the prestigious Shanti Swarup Bhatnagar prize, Dr Sangwan said he had conducted the procedure on about 25 patients with good results. This had been published in international scientific magazines.

He is now in the process of developing tools to help doctors.

Leber Congenital Amaurosis

Children down with the rare ocular disorders that result in gradual loss of sight can hope for a cure. Doctors are working on a gene therapy to correct this problem caused by consanguineous marriages.

Though this therapy is in vogue abroad, LVPEI says it is the first centre to carry out research on this procedure. Technically called LCA or Leber Congenital Amaurosis, doctors would refer patients to a gene analysis after studying them for indications.

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Stem cell therapy for cornea treatment

Mogato: Never-ending lessons

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Mogato: Never-ending lessons

Back on Earth, SpaceX planning more private flights to space

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The Hawthorne firm, celebrating its mission to the International Space Station, now turns to sending astronauts as well as cargo, and to building a huge new rocket to launch U.S. security satellites. SpaceX, the upstart Hawthorne company that shot a capsule to the International Space Station and back this week, won't have much time to savor its first major success.

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Back on Earth, SpaceX planning more private flights to space

Space travel agent's creativity takes flight

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Craig Curran, an accredited travel agent for Virgin Galactic, the world's first space tourism business, has sold exactly two tickets since getting the job in early 2011. And one of those tickets was to himself.

To be fair, it's not easy selling $200,000 tickets (with a $20,000 deposit payable up front) for a suborbital day cruise in which the inaugural flight hasn't even been announced. It's basically selling a promise for something that will probably happen in the vague near future.

But as Curran prefers to think of it, his customers are "investing in the birth of an industry."

"They're not getting shares or a piece of the company," he clarified. "But they are trailblazers. They'll be among the first 500 civilians to leave the Earth's atmosphere."

Before Curran was picked to join Virgin Galactic's global sales team - he's one of 140 agents worldwide - the 30-year travel agent vet from Rochester, N.Y., had to prove that he has, as Tom Wolfe might say, the right stuff. In addition to marketing plans and a resume, he was asked to demonstrate an "enthusiasm for space travel."

And how does one demonstrate such a thing?

"I explained to them that I've been a passenger in fighter jets at air shows," Curran said. "I own a Ferrari. I've gone to high-speed driving schools. I like guns. I'm mechanically inclined and scientifically wired."

In other words, he represents the type of person who'd feasibly spend big money to be shot about 60 miles above the Earth's surface. Finding customers - gun-toting, science-loving, Ferrari-driving people like Curran - has been a unique challenge.

It's not like it was back in Curran's travel agent heyday in the '80s and '90s, when customers would actively seek him out. For space tourism, he's had to be creative.

"I do speaking engagements," he said. "I'll speak in front of anybody who'll have me."

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Space travel agent's creativity takes flight

Big week for commercial space flight, big week for Louisville-built Dream Chaser

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LOUISVILLE -- Images from space dominated the week and fired up imaginations all over again.

An unmanned capsule launched by a private company docked with the International Space Station 240 miles above Earth, exchanged cargo with the astronauts living there and then plummeted through the atmosphere into a picture-perfect splashdown in the Pacific Ocean on Thursday morning.

The accomplishment was a first for the burgeoning commercial space sector and California-based SpaceX, helmed by 40-year-old South Africa-born billionaire Elon Musk, was lauded worldwide for its success.

But just two days before the heralded return of SpaceX's Dragon capsule 560 miles off the coast of Baja California, a company much closer to home

Engineering Technician Richard Santos wipes down the surface on the Dream Chaser space vehicle at Sierra Nevada Space Systems in Louisville on May 31, 2012. ( MARK LEFFINGWELL )

Sierra Nevada Corporation Space Systems, headquartered on the Colorado Technology Center campus in Louisville, passed one of the most complex tests it has faced in its attempt to launch a seven-person orbital vehicle -- called the Dream Chaser -- into space by 2016. Known as a captive-carry test, the effort required the 40-foot-long and 25-foot-wide Dream Chaser to be lifted by an Erickson Air-Crane helicopter into the skies above Rocky Mountain Metropolitan Airport and put through a battery of tests measuring its aerodynamic flight performance.

Last week's successful result paves the way for the sleek space plane to undergo autonomous approach and landing tests at Edwards Air Force Base in California this fall before finally heading skyward on an Atlas V rocket.

"We're really excited because after taking it on paper for many years, we're actually starting to fly the real thing that NASA is going to be taking to space," said Mark Sirangelo, who heads up Sierra Nevada's 230-employee space systems division in Louisville.

He doesn't begrudge SpaceX's day in the sun

In this image provided by NASA with clouds and land forming a backdrop, the SpaceX Dragon commercial cargo craft is grappled by the Canadarm2 robotic arm at the International Space Station on May 25. (AP Photo/NASA)

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Big week for commercial space flight, big week for Louisville-built Dream Chaser

Dixon heads pre-qualifying practice

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Scott Dixon provided a rare bit of sunshine for Ganassi, on a chilly Saturday morning in Detroit that proved not to many Honda-powered cars' liking ahead of qualifying at Belle Isle.

The session had barely got underway when there was a quick red flag for a spin by Ryan Briscoe on his out lap, and the 2.07-mile, 14-turn street course had only just reopened when Oriol Servia then spun and went into the wall at turn 14 with a heavy impact that badly damaged the right-front of the Panther/DRR car.

Emphasising how much everyone was really pushing things close to the limit on this unfamiliar circuit, Dario Franchitti was next to spin five minutes into the next green session just before the midpoint of the one hour practice session. He lost the #10 car at turn 5, but mercifully in his case kept the car off the barriers.

After Franchitti's mishap, there was a finally a decent period of green flag running for the remainder of the session, which survived a brief bit of off-roading for Helio Castroneves out of turn 12, Ed Carpenter taking to the run-off area at turn 8 with around six minutes remaining, and a harmless spin by Justin Wilson that he was able to deal with without assistance.

Off the track in pit lane, there was also some wheel-to-wheel contact between the two Ryans in the field when Ryan Hunter-Reay was ushered out of his pit box right into the path of Penske's Ryan Briscoe who was also exiting the pits and returning to the track. No serious harm was done, but Hunter-Reay was given a 60 second stop-and-hold penalty for the unsafe pit release.

During this time, Scott Dixon had gone top of the timesheets with a lap of 1:11.3913, over a quarter of a second faster than Will Power who had a similar margin over Hunter-Reay. Both drivers at the front would shave a little more time off with their last flying laps of the morning.

In total, there were seven Chevrolet cars in the top ten - including all three Penske cars - and just three Hondas, with Dixon joined by Justin Wilson and Simon Pagenaud. Graham Rahal briefly nudged his way into the top ten in the final minutes, but was summarily hustled out again by Tony Kanaan and JR Hildebrand before the chequered flag came out to end proceedings.

Qualifying for the Chevrolet Detroit Belle Isle Grand Prix takes place at 11.45am (4.45pm BST). After the unique format seen at Indianapolis, qualifying reverts to the usual road/street system with two groups having 15 minutes to set a time, and the top six from each group moving forward into a single ten minute Top 12 session. The top six from this round fight it out for pole in the Firestone Fast Six to complete the grid order.

The race itself is scheduled to take place on Sunday afternoon at 3.45pm (8.45pm BST) after a final early morning half-hour warm-up opportunity.

Full practice 3 times available.

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Dixon heads pre-qualifying practice

Queen heads to the races as Jubilee kicks off

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The Queen spent the first official day of her Diamond Jubilee celebrations indulging in one of her favorite passions - horses.

The 86-year-old monarch, who is celebrating six decades on the throne with four days of festivities, attended the Epsom Derby - considered one of the most exciting and prestigious horse races in the world.

She and her husband, the Duke of Edinburgh, 90, were given an affectionate welcome from a crowd of about 130,000 race-goers as the royal motorcade entered the stadium in Surrey, southeastern England, and took a quick spin along the course.

The Queen, wearing an elegant floral print dress and royal blue jacket and hat, joined a large party including the Duke of York and his daughters Princess Beatrice and Princess Eugenie, before visiting the paddock to inspect some of the horses running in the Diamond Jubilee Coronation Cup.

Her Majesty's love of all things equine is well known - she is a racehorse owner, breeder and trainer, and her horses have competed at the highest level. While one of her animals has yet to win the Epsom Derby, in 1953 her horse Aureole came a close second. This year, she had no runner in the race.

With the jubilee party officially kicking off Saturday across Britain, thousands of miles of bunting was festooned over England and Wales, and almost 9500 road closure applications were granted for street parties.

Heathrow Airport rehearsed worst-case baggage-handling situations to prepare for the arrival of nearly 800,000 overseas travelers and well-wishers, and supermarket chain Tesco expects to sell 200,000 bottles of champagne.

Despite the countrywide excitement, there was a dark cloud hanging over the celebrations, literally - but although the day started out bleak for parts of England, the weather began to clear in several places by the afternoon.

The extended public holiday weekend began with a bang Friday night in Portsmouth, on the southern coast of England, where the HMS Diamond fired a 21-gun salute in honour of the queen.

On Sunday, Her Majesty will board a royal barge on the River Thames and lead a flotilla of 1000 vessels in a grand maritime pageant. More than a million people are expected to gather along the river to witness the spectacular event.

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Queen heads to the races as Jubilee kicks off

SpaceX's Success Should Lead to NASA Being Cut to the Bone

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SpaceX?s Dragon capsule is now safely down from the ISS, showing that private enterprise can do at least some of this space stuff at vastly lower cost than a creaking governmental bureaucracy like NASA. Bloomberg then makes the entirely incredible argument that this means that NASA should aim to think big and bump up its ...

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SpaceX's Success Should Lead to NASA Being Cut to the Bone

Nasa sets sights on U-tapao for study base

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SINGAPORE : Nasa has asked the Thai government and army for permission to use U-Tapao airport in Rayong as a base to conduct atmospheric studies, a military source says.

The source said Nasa aims to begin its studies at the airport next month.

"Nasa will work in an open and transparent way and will welcome Thai officers to join them in their studies and to transfer knowledge to local scientists. This involves Nasa and is unrelated to military or security concerns," the source said.

US Defence Secretary Leon Panetta lays out the new US Asia-Pacific strategy at the International Institute for Strategic Studies (IISS) 11th Asia Security Summit in Singapore on Saturday. (Reuters photo)

Defence Minister Sukumpol Suwanatat added that the US was also interested in setting up a regional humanitarian and disaster relief centre at the airport.

He said he agreed with the idea of the centre on humanitarian grounds.

But the decision would be made by the Thai government, ACM Sukumpol said during his trip to Singapore to attend the Shangri-La Dialogue, an intergovernmental security forum, which will conclude today.

ACM Sukumpol also met US Secretary of Defence Leon Panetta at the event.

"Do not fear that the US will set up a military base in U-Tapao," ACM Sukumpol said after a 15-minute talk with the US secretary of defence on Friday.

"It has not been like that in the past. As we are friends, we need to support each other," he said. "The US can under normal circumstances use U-Tapao in accordance with our agreement."

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Nasa sets sights on U-tapao for study base

NASA expects quick start to SpaceX cargo contract

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The top NASA manager in charge of the agency's commercial cargo transportation program hailed SpaceX's demonstration flight to the International Space Station as a success and indicated approval for continued resupply missions under a $1.6 billion contract would be a mere formality.

Dragon spent six days at the International Space Station. Credit: NASA The Dragon spacecraft made an on-target splashdown in the Pacific Ocean on Thursday, ending a nine-day mission that set out to prove the capsule's ability to safely reach the space station, deliver supplies, and return equipment to Earth.

The SpaceX-owned spacecraft will be the only vehicle in the space station's fleet of resupply freighters able to return to Earth intact with cargo. Other robotic cargo spacecraft built in Russia, Europe and Japan dispose of trash and burn up in the atmosphere.

Alan Lindenmoyer, manager of NASA's commercial cargo development program, said the flight looked to be 100 percent successful.

"We'll get a quick-look report from SpaceX next week, and then we'll await a final post-flight report several weeks later," Lindenmoyer said.

NASA invested $396 million into SpaceX under a public-private partnership agreement signed in 2006. The space agency released payments to the California-based company as it met design, testing and flight milestones.

Following the announcement of the space shuttle's retirement, NASA started investigating new ways to transport critical spare parts, food, experiments, and other geat to the space station. But no companies had the ability to do the job, and NASA wished to set its sights on more ambitious expeditions into the solar system.

After surveying the market, NASA established the Commercial Orbital Transportation Services program to help fund private development of rockets and spacecraft to resupply the space station.

"You have turned those hopes into a reality today," Lindenmoyer said to Elon Musk, SpaceX's CEO and chief designer, following Thursday's splashdown.

SpaceX and Orbital Sciences Corp. won agreements with the COTS program. Orbital's first flight to the space station could launch as soon as October.

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NASA expects quick start to SpaceX cargo contract

NASA ISS On-Orbit Status 02 June 2012

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ISS On-Orbit Status 06/02/12

All ISS systems continue to function nominally, except those noted previously or below. Saturday - Crew off duty.

After wakeup, CDR Kononenko performed the routine inspection of the SM (Service Module) PSS Caution & Warning panel as part of regular Daily Morning Inspection.

The six Exp-31 crewmembers joined in conducting the regular weekly three-hour task of thorough cleaning of their home, including COL (Columbus Orbital Laboratory) and Kibo JPM (JEM Pressurized Module). ["Uborka", usually done on Saturdays, includes removal of food waste products, cleaning of compartments with vacuum cleaner, damp cleaning of the SM dining table, other frequently touched surfaces and surfaces where trash is collected, as well as the sleep stations with a standard cleaning solution; also, fan screens and grilles are cleaned to avoid temperature rises. Special cleaning is also done every 90 days on the HEPA (high-efficiency particulate air) bacteria filters in the Lab.]

As part of Uborka house cleaning, Oleg, Gennady & Sergei completed regular weekly maintenance inspection & cleaning of fan screens in the FGB (TsV2), Group E fan grilles in the SM (VPkhO, FS5, FS6, VP), and the weekly checkup on the Russian POTOK-150MK (150 micron) air filter unit of the SM's & FGB's SOGS air revitalization subsystem.

FE-2 Revin also handled the routine daily servicing of the SOZh system (Environment Control & Life Support System, ECLSS) in the SM. [Regular daily SOZh maintenance consists, among else, of checking the ASU toilet facilities, replacement of the KTO & KBO solid waste containers, replacement of EDV-SV waste water and EDV-U urine containers and filling EDV-SV, KOV (for Elektron), EDV-ZV & EDV on RP flow regulator.]

FE-6 Pettit conducted the regular (~weekly) inspection & maintenance, as required, of the CGBA-4 (Commercial Generic Bioprocessing Apparatus 4) and CGBA-5 payloads in their ERs (EXPRESS Racks) at Lab O2 & O1, focusing on cleaning the muffler air intakes.

Kononenko, with Padalka attending for "knowledge handover", completed the periodic maintenance of the active Russian BMP (Harmful Impurities Removal System) by starting the "bake-out" cycle to vacuum on absorbent bed #1 of the regenerable dual-channel filtration system. The process will be terminated at ~4:55pm EDT. Bed #2 regeneration will be done tomorrow. [Regeneration of each of the two cartridges takes about 12 hours and is conducted only during crew awake periods. The BMP's regeneration cycle, normally done every 20 days, is currently performed four times more frequently (last time: 5/14 & 5/15).]

FE-3 Acaba sequentially initiated and monitored charging of four Makita batteries for use with the Cardiopres blood pressure device during the next 24-hr ESA ICV (Integrated Cardiovascular) Ambulatory Monitoring session.

Don Pettit closed the protective shutters of the JAXA Kibo laboratory window to avoid its heating during the upcoming high Beta angle regime. [Shutter closure should be verified 12 hrs (as a margin) before the Betas reach more than +60 deg.]

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NASA ISS On-Orbit Status 02 June 2012

ASCO Presentations Highlight Clinical Utility of Caris Target Now™ in Molecular Profiling of Breast and Head and Neck …

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CHICAGO, June 2, 2012 /PRNewswire/ --

--TLE3 Biomarker Over-expressed in HER2-positive, Hormone Receptor-positive, and Triple-negative Breast Cancers --

-- EGFR status May Facilitate Therapeutic Decision-making in Head and Neck Cancer --

Caris Life Sciences announced today the utility of the company's Caris Target Now evidence-based molecular profiling service in the characterization of breast and head and neck cancers. These data were presented today at the 2012 annual meeting of the American Society of Clinical Oncology (ASCO).

"By combining state-of-the-art genomic sequencing technology with a rigorous review of the clinical literature, Caris Target Now provides tumor-specific biomarker information, enabling physicians to make more informed, individualized treatment decisions for their patients," said Sandeep Reddy, MD, clinical professor of medicine at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Loapracticing oncologist and clinical advisor to Caris Life Sciences. "The data presented today have potentially important predictive implications for patients with breast and head and neck cancers, as the molecular profiling information may point the way toward personalizing therapy based on tumor genetics."

Breast Cancer Data

In a poster presentation today, Gargi Basu, Ph.D., and colleagues at Caris Life Sciences, presented results from the first study providing a comprehensive review of transducin-like enhancer of split 3 (TLE3) expression in breast cancer subtypes. They described TLE3 as a transcriptional repressor that influences tumor growth and microtubule stability; its expression in epithelial tumor cells may reflect that these cells require the expression of TL3 to maintain their undifferentiated state. The expression of TLE3 is also associated with response to taxane therapy in patients with breast cancer.

Working with tumor cells collected from 978 breast cancer patients, the investigators employed two different technological platforms used in Caris Target Now -immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) - to gather information on four biomarkers: TLE3 (M-201), ER(1D5), PR(PgR636), and human epidermal growth factor receptor 2 (HER2)/neu (Polyclonal). IHC analysis of the four biomarkers was conducted at the protein level, and FISH was used to determine amplification of HER2/neu. Samples were then sub-classified as hormone receptor (HR)-positive (i.e., estrogen receptor [ER]-positive and/or progesterone receptor [PR]- positive), HER2-positive (either at the protein level or amplified by FISH), or triple-negative (i.e., lacking in ER, PR, and HER2/neu).

Overall, 351 (36%) of the patients were HR-positive, 150 (15%) were HER2-positive, and 477 (49%) were triple-negative. TLE3 was expressed in 82% of the HR-positive patients, 73% of the HER2-positive patients, and 61% of the triple-negative patients. To further investigate TLE3 expression in the patient subtypes, Dr. Basu and colleagues performed a pairwise Fisher's Exact Test between the various pairs; this analysis revealed that for all pairs, the ratios of TLE3-expressing individuals were significantly different. The largest difference was observed between the HR-positives and the triple-negatives (82% vs. 61%, respectively; p=2.509e-10), suggesting that the HR-positives have a higher likelihood of responding to taxane therapy. The HER2-positives, at 73%, had a ratio that was significantly higher than the triple-negatives and significantly lower than the HR-positives.

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ASCO Presentations Highlight Clinical Utility of Caris Target Now™ in Molecular Profiling of Breast and Head and Neck ...

Holly Valance – State Of Mind Official Music Video © 2003 – Video

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01-06-2012 10:51 Holly Valance - State Of Mind Official Music Video. ? & © 2003 London Records 90 Limited. Tecnical data before the upload: Original Video Format: MP4 (Codec H.264 - 7000Kbs Variable Bitrate - 2 Pass Encoding) Original Video Size: 179.638Kb; 1280x720 (16.9 WideScreen High Definition Upscaled - De-Interlaced) Frame Rate 25ps - Zoom 100% Original Audio Codec: MPEG-4 AAC 320Kbs Variable Bitrate NOTE: All the comments are not strictly related to this video will be removed.

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Holly Valance - State Of Mind Official Music Video © 2003 - Video