Smart Imaging Technologies adds archiving and storage of digital slides in Aperio SVS format

Logo_sitWith the latest version of Simagis Live server, administrators have an option to archive and store digital slides in a version of TIFF format also known as BigTiff or Aperio SVS file format. 

Advantage of this slide format, introduced to Digital Pathology by Aperio, is that it is open and supported by the latest version of public Libtiff library. It is also supported by free desktop software applications such as Aperio’s ImageScope slide viewer.

Simagis Live servers support various compression options for SVS files including both lossy JPEG compression and lossless options such as JPEG2000 or LZW that may be required by FDA in the future to preserve diagnostic image quality.

With Simagis Live servers, users already could upload, view, share and analyze digital slides from different scanners including Aperio, Hamamatsu, Mirax, Leica, Mikroscan, DigiPath, Huron and others. Now, with the option to store slides in SVS format, they get single unified digital slide archive interchangeable with other servers and desktop viewers. This feature is especially valuable for organizations that have several scanners from different vendors and need an integrated solution for viewing, sharing and analyzing digital slides.

This option is also valuable for scanner manufacturers who use Smart Imaging Technologies servers under their own brands to provide slide sharing and analysis solutions to end-users. They can assure users that slides are stored in an open format accessible by third-party software.

About Smart Imaging Technologies

Logo_im_solutionWe provide web servers and applications for viewing, sharing and analyzing whole slide images. Our servers support most digital slide formats, can be easily integrated with various scanners for a single click slide upload, and deployed on premises or on High Performance Computing Cloud.  For details about technology and solutions manufacturers and integrators may contact support@simagis.us .

End-users can learn more and sign-up for free web service at web-pathology.net.

 

Source:
http://feeds.feedburner.com/DigitalPathologyBlog

X-rays, digital pathology and iPads: The network healthcare evolution

PathCentralScreenShot-1_5-11-2012

 It is just a matter of time that pathologists too will recognize the value of wireless connectivity, coordinating care, analytical tools for diagnosis and management and closer follow up, all enabled through mobile computing and digital pathology.

Xray-ipadsAt the rate technology has changed everything else in our lives, by now we should have the equivalent of tricorders in our smartphones—instant access to our health statistics collected by sensors in our clothes and pulled into our individual health history in the cloud. We should be able to Skype our physician, text our pharmacist, and get both a blood sugar measurement and an MRI at Starbucks while waiting for a grande latte.

Except for the MRI part, all of that is doable today. Thanks to the big stick provided by the Affordable Care Act in the US, some healthcare organizations are pushing more aggressive use of network bandwidth and cloud technology:

  • Monitoring patients’ health more proactively with networked devices, ranging from wirelessly networked medicine bottle lids to worn or embedded sensors that report back on vital signs;
  • Coordinating care with the help of analytic tools in the cloud and a wealth of individual and collective patient data; and
  • Connecting physicians directly with patients over PCs or mobile devices for between-appointment follow-ups.

Those things can’t be pulled off without cloud technology, whether it’s hosted internally in a health organization’s data center or elsewhere. But ask any random sampling of physicians, technologists, and health industry observers. They’ll tell you technology isn't restraining the next big paradigm shift in health care. The bandwidth is willing.

“It’s less about the technology holding the industry back, and more about the reimbursement model for healthcare,” says Kenneth Kleinberg, senior director of research and insights at The Advisory Board Company, a global healthcare research, technology, and consulting firm. “Quality hasn't been rewarded, physicians don’t have incentives to share data, and patients are freaked out about privacy. Healthcare isn't a system—it’s a bunch of individual entities looking out for themselves. Just adding more bandwidth to a broken system doesn't work.”

Real technological change in health care requires changing the “work culture” of health organizations and people’s confidence in health IT systems, says Harry Kim, senior director of Hewlett-Packard’s healthcare group. But other complex (and heavily regulated) businesses have embraced change long ago. Citing ATMs, Kim says, “If we can trust our money to a machine, we can do it with healthcare.”

That’s why health organizations are looking outside of their industry for inspiration. “The companies bringing the biggest changes to medicine today are companies like Cisco, EMC, Apple, and Microsoft,” says Dr. Elliot Fishman, Director of Diagnostic Imaging and Body CT at Johns Hopkins Medical Center. Technology from the consumer sector (such as mobile devices and apps, cloud computing, and even gaming) is seeping into the healthcare field and being seized upon by care providers to improve the connection between physician, patient, and data.

To get an idea of how bandwidth can change medicine, we talked to people on the front lines of medical technology at two of the most well-known hospital systems in the US: Johns Hopkins and the University of Maryland Medical Center. We also caught up with technology and digital health service providers. What we got was a snapshot of organizations that are already working to transform medical care with networked technology, while trying to overcome organizational inertia to make it happen.

Driven by data

The first wave of change that healthcare organizations have dealt with (or are still dealing with) is what Kim calls the “digitization of sick care.” Nearly 80 percent of healthcare is dealing with chronic illness. To improve care for patients with chronic health problems, health providers need to be able to effectively monitor and capture the right data from them, pull it back into electronic medical records, and make it available to both patients and physicians to act upon.

The problem is that many health record systems weren't built to handle those tasks. Healthcare systems have had electronic health records for decades; the problem is the systems lack standardization. These carry with them the sorts of software and schema hangovers that plague every data integration project.

“At Hopkins, it started a long time ago with a longitudinal patient record that pulled in from all our systems,” says Stephanie L. Reel, Vice Provost of Johns Hopkins University, Vice President of Information Services at Johns Hopkins Medicine, and CIO for both the university and hospital. The system acts as a repository for information from all of the hospital systems’ various health systems.

“But in spite of the fact that I think we've done a good job over the last 25 years, we've now realized we didn't,” Reel says. The effort required to get all of the data normalized from each of the systems was “too expensive, cumbersome, and not always possible.”

So Hopkins is replacing its homegrown system with one from Epic, a hosted system with a single, patient-centric database. Reel says that when it’s implemented, the system will “give each patient control over his or her own records.” Patients finally gain complete access. Since it’s a single integrated system, all of an individual's data is there for each caregiver—their allergies, test results, medications, etc. Epic's portal can even be accessed through mobile apps for Apple iOS and Android devices.

Epic's Canto electronic medical record app for iPad.

But on top of that, the data will also be used to mine information on how well different courses of care worked for patients. This should help tailor care based on patients' own conditions and the outcomes of people with similar cases. “You can look at a population base that has benefited from treatment,” Reel said. “We can learn from our own cases, but also if done appropriately, can learn from interventions elsewhere. This gives us the opportunity to do personalized medicine—based on previous cases, we can be able to predict when patient will benefit from one type of intervention or another—or, from their genetic makeup, might be able to decide if treatment won’t help.”

BYOD medicine

Physicians aren’t waiting for their central IT departments to achieve the nirvana of centralized healthcare data. They’re finding their own ways to get access to the information they need, when they need it—pushing health providers to build Web portals and other applications that give them access to medical records anywhere. One of the most visible signs of change is the adoption of the iPad and other mobile devices by physicians.

Thanks to more reliable and more widely available wireless bandwidth, the iPad has become an essential tool for clinicians. Last October, the Department of Veterans Affairs moved to open up its network so that doctors could use their own mobile devices. While other health systems have been slow to officially adopt the iPad and other devices, John Kornak, Director of Telehealth at the University of Maryland Medical Center says, “A BYOD (bring your own device) mentality is starting to take shape among physicians, and more mobile apps are starting to find their way into use.”

Kornak says that there is a strong push from doctors to find mobile apps that make it easier and more seamless for them to connect to health data such as charts and radiology images. “Physicians are telling us if we don’t have [the apps they need], we need to have a development partner and build it ourselves. They're really urging us to not focus on what the standards are—we need to be open to any devices on market, and keep them in mind when building solutions.”

One of the most obvious applications for the high-resolution screen of the latest iPad is displaying medical imagery. By pulling up images from CT scans and MRI scans on their iPads, Hopkins’ Dr. Fishman says surgeons now use the iPad to explain procedures to patients more effectively. “Doctors can look at their cases in real time. Now my clinicians are looking at the information I generate as it’s created. They can pull down CT slices in 2 seconds. It’s very fast and interactive. They can bring the image to the bedside or in the office.”

That mobility and ease of access pays off in another way: time. “When you speak to surgeons at Hopkins,” says Fishman, “they say that they save about an hour of time each day from using the iPad. And that’s a big deal—instead of going home when their kids are asleep, they get home when their kids are awake.” Fishman says he’s been at the beach and on airplanes and has been able to look at radiology images for consults.

That power doesn’t just come from the digitization of raw information, though. It only works, Fishman says, when the networking piece becomes transparent. “The end-user experience has to be that it just happens," he says, "not typing 20 codes in for access and hoping that it works.”

Read more.

Sean Gallagher / Sean is Ars Technica's IT Editor. A former Navy officer, systems administrator, and network systems integrator with 20 years of IT journalism experience, he lives and works in Baltimore, Maryland.

 

 

Source:
http://feeds.feedburner.com/DigitalPathologyBlog

AccelPath, Inc. Letter to Shareholders

05/29/2012 | 08:35am 

Accelpath_top

AccelPath, Inc. (OTCBB: ACLP) ("AccelPath" or the "Company") issued the following Letter to Shareholders today outlining the Company's overall business strategy and operational highlights and achievements since the beginning of calendar year 2011.

The Company's overall business strategy is to expand its core business of providing a unique, viable and efficient solution for enabling digital telepathology, while capitalizing on its 3D imaging technology. The proven 3D technology has several direct applications in digital telemedicine and will continue to be developed by AccelPath. Other related and significant applications for the 3D technology, such as security and engineering, will be developed through joint ventures both domestically and internationally.

During 2011, the Company developed its core workflow technology while negotiating client and provider agreements and establishing regional business "pods." The Company's regional presence provides a basis for its eventual national footprint. A portion of this activity enabled developing the "loop" of complete automation and digital transfer of pathology information from laboratories to skilled pathologists and back to awaiting physicians. These physicians require fast, reliable pathology reports for their patients requiring immediate diagnoses and treatment of significant diseases. The Company began generating revenues towards the end of 2010.

Selected highlights and achievements include:

  • Completed base level portion of workflow IT technology. AccelPath has developed a unique and proprietary suite of HIPAA compliant software tools to enable creation, submission, and reporting of pathology cases and to provide secure online access to reports. AccelPath works with pathologists, laboratory staff and clinical office managers to design and further develop and advance the toolset. This solution is unique in its capability of handling both glass and digital slides, hence, providing an automated solution for all pathology cases. Also, the Company's technology is novel in its ability to be customized for any pathology laboratory practice or interpretation center based upon the software's modular configuration and universal interfacing with existing disparate software toolsets.
  • On-going discussions with leading slide scanner manufacturing companies to enter into strategic partnerships. AccelPath is in discussions with leading slide scanner manufacturers to provide clinics and hospitals with worksite planning, technical services including software interfaces and scanner operations, network engineering, professional pathology services and post-implementation support. Scanner deployments will allow the Company to further digitize its product offerings, allowing advancement of its strategy of providing efficient, timely, fully automated, digital pathology services using existing electronic information technologies.

AccelPath is collaborating with these scanner manufacturers to facilitate any near-term regulatory approvals for scanners use in pathology interpretations. Regulatory approval for scanners will complete the pathology digitalization "loop," allowing the Company to be a leader with a complete work flow solution and transmission solution for the pathology market.

  • Developing inter-site telepathology network. The Company is working with a significant, expanding hospital system in Massachusetts. AccelPath has been approached to develop, implement and manage an intersite telepathology network for optimization of resources across multiple hospital locations.
  • Completed administrative components of merger. In May 2011, the Company changed its name from Technest Holdings, Inc. to AccelPath, Inc., which reflects its current business focus. Commensurate with its name change, the Company changed its trading symbol to "ACLP."
  • Increase customer base and branding. This will allow the Company to continue expanding its footprint nationwide as a recognized reliable, efficient and high-quality provider of digital pathology technology.

Since AccelPath was formed, the Company has been able to achieve its growth and infrastructure development objectives. Management believes the remainder of 2012 should be another exciting period for AccelPath, particularly as the Company expects to further implement its digital pathology workflow solution, continue to expand its services and increase customer penetration while forming strategic alliances. In addition, the Company will take advantage of the 3D technology as it relates directly to digital telemedicine, while developing the non-core 3D imaging technology applications with strategic partners. With its experienced management team, AccelPath expects to meet these established objectives for 2012.

(Added links and graphic above not part of original letter)

 

Source:
http://feeds.feedburner.com/DigitalPathologyBlog

Annoucing MikroScan Qumulus, New Cloud-based Digital Pathology Communications Service for Viewing, Management, Sharing, and Analysis of Whole Slide Images

MikroScan Qumulus service offers the fastest, easiest, and most affordable path to step into the future with cloud-based digital pathology communications.

Vista, CA:  Whole slide imaging (WSI) systems manufacturer, MikroScan Technologies, adds a product to its digital pathology communications toolset. MikroScan Qumulus is a monthly service that provides an easy means for hospitals, researchers, or pathologists to store, manage, view, and instantly share whole slide images from anywhere with an Internet connection. MikroScan offers a free 90-day trial account, which takes only minutes to set up and includes 50 gigabytes of storage space.

The new cloud-based service works hand-in-hand with MikroScan’s desktop whole slide scanner, MikroScan D2, and image acquisition software, Q-Skan. The latter can automatically upload the scanned image to your Qumulus account as it saves, providing near-instant remote access to pathologists anywhere in the world.

“We are ecstatic about Qumulus. Its remote Web access features makes pathology communications a breeze and will save our customers thousands of dollars annually in travel and slide transport costs.” Said Bob Goerlitz, president and founder of MikroScan Technologies, Inc. “With our D2 scanner’s low price point and now our Qumulus cloud service low rates, we have effectively removed all economic barriers to entering digital pathology. And with our new leasing options, even the capital expenditure is no longer a speed bump. If you are a pathologist, now there is no reason not to have a MikroScan on your desk.”

“With its immediate remote sharing capability Qumulus is especially useful for consults, research, tumor boards, and educational applications,” said Victor Casas, chief technical officer and applications specialist.

MikroScan Qumulus is Web-based so pathologists can use a Web browser (i.e. Internet Explorer) to access their cases from virtually anywhere. There is no software or hardware investment required, and no need for technical expertise or I.T. personnel to install or maintain.

MikroScan Qumulus is the most affordable service of its kind and costs a fraction of what competing solutions charge. The monthly service includes all cloud software and hardware upgrades as well as automatic backups. There are no storage limits, and no data transfer charges.

MikroScan offers 20-40 minute online product demonstrations of both its scanner and Qumulus viewer. Go to http://www.mikroscan.com or call (760) 736-2180 to request a demo.

About MikroScan Technologies, Inc.

MikroScan Technologies, Inc. founders have been engaged in the design, sales, and marketing of high quality laboratory instruments for more than 26 years. The company specializes in the development of cutting edge whole-slide imaging (WSI) systems and communication tools designed for pathology, biology and research applications. With game changing technology and pricing, MikroScan products represent a leap in advancement and convenience in the evolution of WSI and digital pathology. MikroScan centers its product development on speed of slide image acquisition, exceptional imaging quality, and unmatched affordability that breaks through traditional barriers to digital pathology. For further information visit: http://www.MikroScan.com

Source:
http://feeds.feedburner.com/DigitalPathologyBlog

"St. Dennistoun Mortuary" Coin-Operated Automaton LIVE AND IN ACTION!!!

Regular readers of Morbid Anatomy might remember a recent post on this blog about an amazing 1920/30s era coin-operated automaton depictingthe St. Dennistoun Mortuary (yes, really!) that will be going to auction this Saturday. Skinner Auction House just sent along a video of this magnificent machine in action.

Press play above and enjoy. WOW.

The piece is estimated to go for between $4,000-$6,000 as part of an upcoming Science, Technology & Clocks auction taking place Saturday, June 2 at 10:00AM. Full lot description from the Skinner Auctioneers website follows:

Lot 207
"St. Dennistoun Mortuary" Coin-Operated Automaton, attributed to Leonard Lee, c. 1900, the mahogany cabinet and glazed viewing area displays a Greek Revival mortuary building with double doors and grieving mourners out front, when a coin is inserted, doors open and the room is lighted revealing four morticians and four poor souls on embalming tables, the morticians move as if busily at work on their grisly task and mourners standing outside bob their heads as if sobbing in grief, ht. 30 1/2, wd. 24, dp. 17 1/4 in.

Estimate $4,000-6,000

Brass coin plate stamped J. Dennison Leeds NO. 80

As I said before, whoever buys this, please (please!!!) let me come over to meet it! You can find out more about it here.

Source:
http://morbidanatomy.blogspot.com/feeds/posts/default?alt=rss

Seeking adventure and profit on Travel Channel's treasure hunt

Everyone loves adventure with the chance of monetary reward.

On Sunday, the Travel Channel lets people live such excitement vicariously with "Gem Hunt." The one-hour special takes viewers along with veteran gem dealer Ron LeBlanc, geologist Bernie Gadboury and jewelry expert Diane Robinson, as they search remote regions of Madagascar for rare pink sapphires, premium blue sapphires and the country's best aquamarines.

Quests like these involve more than the ability to spot the prettiest jewels.

"You have to know your geology, your mineralogy, your topography, your politics, your economics," says Richard Houck, CEO of the Sterling Hill Mining Museum in Ogdensburg. "If you want to have a successful effort, you cannot go underprepared. Someone going down there without proper preparation and planning can find themselves in a very difficult and unproductive [situation]. You gotta do your homework."

Years ago, Houck went on expeditions at mining locations in Brazil, Peru, England, Sweden and Canada. He says that while such expeditions have gotten even more difficult now as so much of the planet has been explored and overmined the basic motivations remain the same.

"First is monetary compensation," says Houck. "You hope you are going to make some money, maybe some big money. [Second is] the adventure.

"There's also the Easter Egg Hunt Syndrome. We all like to seek, explore and discover."

Or watch others seek, explore and discover.

With cameras in tow, LeBlanc, Gadboury and Robinson travel to remote regions of the island nation off the coast of Africa. From them, viewers get a unique look into the gem industry, its risks and dangers and the obstacles faced getting a gem from a mine to the jewelry store.

It might even inspire a few to set off on adventures of their own.

Go here to read the rest:

Seeking adventure and profit on Travel Channel's treasure hunt

Travel Snaps

Jack and Judy Stransky, Marge Welch and Rita Foral, all of Omaha, spent 24 days in February traveling in Italy. The four of them first met at Eppley Airport, where they found they were traveling to Italy on the same tour. This picture shows them in Rome in front of the Arch of Constantine. They got to see Rome as few people do in the snow!

Share your photos

Share your travel pictures with us. Just include a copy of The World-Herald in some photos you snap while traveling.

Use our easy online Travel Snaps submission form, and well publish the photos on Omaha.com. From there, readers can vote for their favorites.

We print the overall readers choice for a particular time period in the Living section on Sundays.

Find details, submit entries and vote for your favorites at Omaha.com/contests. Click on the Travel Snaps box.

Copyright 2012 Omaha World-Herald. All rights reserved. This material may not be published, broadcast, rewritten, displayed or redistributed for any purpose without permission from the Omaha World-Herald.

See the article here:

Travel Snaps

Children to be quizzed on happiness and spirituality … from the age of two

Sunday 3 June 2012

THE psychological wellbeing of children as young as two will be assessed as part of a project to regularly monitor the mental health of youngsters in Scotland for the first time.

Pre-school children could be monitored under proposals to assess mental health

Custom byline text:

New project measures psychological wellbeing of Scottish youngsters By Judith Duffy

A new set of "indicators" has been developed which will enable researchers to build up a detailed nationwide profile of the mental health of Scots aged under 17.

The first survey is due to be published towards the end of 2013 and it will subsequently be updated every four years.

Read the original post:

Children to be quizzed on happiness and spirituality ... from the age of two

David Hnyda: Attending Space Camp solidified his dream of space flight

HUNTSVILLE, Alabama -- Here is an Army experimental test pilot, an aspiring astronaut. He has wanted to be in space since childhood.

His childhood goal was to fly - to experience the weightlessness that came with being in space.

"Going to Space Camp, I realized what was going on," he said. "It was going into space. I still want to do it."

So that is how Maj. David Hnyda, now 35, latched even tighter to his childhood ambition, never letting go of it after first attending Space Camp when he was in the sixth grade.

"I am still pursuing," he said.

Last year, NASA announced it was seeking astronauts. Hnyda applied, and he's scheduled to find out this summer if he made the initial round of cuts.

At Space Camp, he said, he learned how much was required to travel and be in space.

"Absolutely, you would say it impacted my choice in majoring in college," he said. "It confirmed that, yes, I do want to try to be an astronaut. It solidified the dream."

The dream flourished at Space Camp in the late 1980s. Growing up in Lilburn, Ga., east of Atlanta, he learned about Space Camp.

"When I went the first time, I did the whole thing," he said. "I had to work a deal with my parents and grandfather. If I could earn half of the money, they would match that, and they would pay the other half."

View post:

David Hnyda: Attending Space Camp solidified his dream of space flight

Kerri-Anne turns heads in red undies

KERRI-Anne Kennerley sure is making the most of her post Dancing With The Stars bod - and is not too keen to hang up her dancing shoes just yet, either.

The TV veteran has stripped off - kind of - for a campaign for Red Undies Week, which raises awareness for kidney disease.

Some 1.3 million Australians are walking around with the "silent killer" and don't know it, so make sure you get checked.

Read more:

Kerri-Anne turns heads in red undies

Computer-designed proteins programmed to disarm variety of flu viruses

ScienceDaily (June 1, 2012) Computer-designed proteins are under construction to fight the flu. Researchers are demonstrating that proteins found in nature, but that do not normally bind the flu, can be engineered to act as broad-spectrum antiviral agents against a variety of flu virus strains, including H1N1 pandemic influenza.

"One of these engineered proteins has a flu-fighting potency that rivals that of several human monoclonal antibodies," said Dr. David Baker, professor of biochemistry at the University of Washington, in a report in Nature Biotechnology.

Baker's research team is making major inroads in optimizing the function of computer-designed influenza inhibitors. These proteins are constructed via computer modeling to fit exquisitely into a specific nano-sized target on flu viruses. By binding the target region like a key into a lock, they keep the virus from changing shape, a tactic that the virus uses to infect living cells. The research efforts, akin to docking a space station but on a molecular level, are made possible by computers that can describe the landscapes of forces involved on the submicroscopic scale.

Baker heads the new Institute for Protein Design Center at the University of Washington. Biochemists, computer scientists, engineers and medical specialists at the center are engineering novel proteins with new functions for specific purposes in medicine, environmental protection and other fields. Proteins underlie all normal activities and structures of living cells, and also regulate disease actions of pathogens like viruses. Abnormal protein formation and interactions are also implicated in many inherited and later-life chronic disorders.

Because influenza is a serious worldwide public health concern due to its genetic shifts and drifts that periodically become more virulent, the flu is one of the key interests of the Institutes for Protein Design and its collaborators in the United States and abroad. Researchers are trying to meet the urgent need for better therapeutics to protect against this very adaptable and extremely infective virus. Vaccines for new strains of influenza take months to develop, test and manufacture, and are not helpful for those already sick. The long response time for vaccine creation and distribution is unnerving when a more deadly strain suddenly emerges and spreads quickly. The speed of transmission is accelerated by the lack of widespread immunity in the general population to the latest form of the virus.

Flu trackers refer to strains by their H and N subtypes. H stands for hemagglutinins, which are the molecules on the flu virus that enable it to invade the cells of respiratory passages. The virus's hemagglutinin molecules attach to the surface of cells lining the respiratory tract. When the cell tries to engulf the virus, it makes the mistake of drawing it into a more acidic location. The drop in pH changes the shape of the viral hemagglutinin, thereby allowing the virus to fuse to the cell and open an entry for the virus' RNA to come in and start making fresh viruses. It is hypothesized that the Baker Lab protein inhibits this shape change by binding the hemagglutinin in a very specific orientation and thus keeps the virus from invading cells.

Baker and his team wanted to create antivirals that could react against a wide variety of H subtypes, as this versatility could lead to a comprehensive therapy for influenza. Specifically, viruses that have hemagglutinins of the H2 subtype are responsible for the deadly pandemic of 1957 and continued to circulate until 1968. People born after that date haven't been exposed to H2 viruses. The recent avian flu has a new version of H1 hemagglutinin. Data suggests that Baker's proteins bind to all types of the Group I Hemagglutinin, a group that includes not just H1 but the pandemic H2 and avian H5 strains.

Recognizing the importance of new flu therapies to national and international security, the Defense Advanced Research Projects Agency and the Defense Threat Reduction Agency funded this work, along with the National Institutes of Health's National Institute for Allergy and Infectious Diseases. The researchers also used the Advanced Photon Source at Argonne National Laboratories in Illinois, with support from the Department of Energy, Basic Energy Sciences.

The methods developed for the influenza inhibitor protein design, Baker said, could be "a powerful route to inhibitors or binders for any surface patch on any desired target of interest." For example, if a new disease pathogen arises, scientists could figure out how it interacts with human cells or other hosts on a molecular level. Scientists could then use protein interface design to generate a diversity of small proteins that they predict would block the pathogen's interaction surface.

Genes for large numbers of the most promising, computer-designed proteins could be tested using yeast cells. After further molecular chemistry studies to find the best binding among those proteins, those could be re-programmed in the lab to undergo mutations, and all the mutated forms could be stored in a "library" for an in-depth analysis of their amino acids, molecular architecture and energy bonds. Advanced technologies would allow the scientists to quickly thumb through the library to pick out those tiny proteins that clung to the pathogen surface target with pinpoint accuracy. The finalists would be selected from this pool for excelling at stopping the pathogen from attaching to, entering and infecting human or animal cells.

Continued here:

Computer-designed proteins programmed to disarm variety of flu viruses

'Nano technology' [program can pay off big for IRSC students

FORT PIERCE A new partnership at Indian River State College's Brown Center for Innovation and Entrepreneurship between its nanotechnology lab and NanoProfessor will take the college to the cutting edge of tomorrow's technology.

So said Kevin Cooper, director of advanced technology at the newly named NanoProfessor Advanced Materials Lab, which officially will be teaching about new-age nano technology studies starting in the fall.

What is nano technology? Nano technology is extremely small scale, said Dean Hart, chief commercial officer of NanoInk Inc. and the NanoProfessor and Nano Science education program in Skokie, Ill.

"Nano-scale is one billionth of a meter, so when you talk about nano technology applications, it's looking at normal biology, physics and material science it's how those sciences work on a very, very small scale," Hart said.

That's 80,000 times smaller than a human hair, according to an IRSC brochure.

IRSC is the first college in the Southeastern United States to offer students access to a fully nano-instrumentation equipped laboratory with an expert-driven curriculum, and student-teacher support materials.

Cooper said IRSC will be offering technician certificates starting in the spring of 2013 that will qualify graduates to seek four-year degrees in fields such as materials science, biology, physics and medicine at large universities.

Cooper said there already is ongoing undergraduate nano research at the Fort Pierce lab where student researchers have been working in partnership with industry clients; they are expecting to have their first publication in the fall.

The new nano program will not only introduce new degrees, but provide real-world research opportunities for students while fostering partnerships with universities and industry. It will provide lab space for scientists and those promoting economic growth in the nano fields.

What is nano research at IRSC looking at now?

Go here to see the original:

'Nano technology' [program can pay off big for IRSC students

Wii U Getting Achievements And Cloud Saves [Rumor]

E3 doesnt start officially until Tuesday, but many publishers will be pushing out news and game reveals starting tomorrow. Nintendo may even get the ball rolling later today with its Nintendo Direct presentation. While we dont expect Nintendo to reveal anything mind blowing during the presentation, a recent rumor suggests that Nintendo will have even more exciting news to share during its proper E3 press conference on Tuesday.

Speaking to anonymous developers working on multiple Wii U projects, Wii U Daily learned that the Wii U will be getting achievements, cloud storage and deep social networking integration. The developers suggest that Nintendo will be showing off these features during its E3 press conference. If true, these rumors suggest a Nintendo that is doing some exciting and innovative things in fields that we have taken for granted thus far.

The first rumor says that the Wii U will be getting achievements called Nintendo Points. They will be similar to Xbox 360 achievements and PlayStation 3 trophies in that players will earn them for completing objectives in game. Unlike the other console manufacturers, however, Nintendo will be bringing a much needed change to the achievement system. As of now, players will only receive points in exchange for completing in-game objectives. Its all kind of superficial and only appeals to the base instinct of wanting to see a number rise. Nintendo Points will offer in-game rewards for completing objectives and getting achievements. Think of a Mario game that unlocks new levels as you earn achievements. Thats what the developers are suggesting.

The second rumor points to Nintendo getting a cloud saving feature just like what Sony and Microsoft offer. Comparably, the Nintendo cloud storage solution will allow players to save their game saves and profiles on the cloud for easy transfer between consoles. The difference between Nintendos and the competitions solution is that Nintendos cloud storage will be free. Sony and Microsoft require that players pay for either PlayStation Plus or Xbox Live Gold respectively to gain access to cloud saves.

The third and most exciting feature is the integration of social media into the Wii Us operating system. The developers specifically point out that Facebook, Twitter and YouTube will be the first services to be integrated. Unlike the other consoles integration, Nintendo is apparently going for a deeper integration that has yet to be seen on a console. The developers say that players will be able to pause a game at any moment to share a screenshot of the game on Facebook or Twitter. The YouTube feature is the most exciting as it would allow players to record and upload gameplay videos to YouTube directly from the console.

A few other details from the developers include a new Mii creation system that relies on a camera API that transfers a persons face onto the Mii proper. The 3DS has this feature as well, but the camera is so low-res that it cant really capture a persons face that well.

The other rumor is a bit more unfortunate. The developers say that porting current projects to the Wii U is harder than originally thought. Fortunately, porting from the Xbox 360 to the Wii U isnt that bad since they have similar architecture. Just like the Xbox 360 before it, porting from the PlayStation 3 is an all-together different beast. It should be expected as the Wii U is rumored to have a quad-core processor similar to the processor on the Xbox 360. The cell processor in the PS3, while powerful, does not make it easy to port to the more traditional CPU architectures.

A lot of the rumors that you see here are entirely plausible and will probably show up at Nintendos E3 press conference or the Nintendo Direct later tonight. The achievements and cloud storage are the most likely, but I wouldnt count out the social networking features either. Nintendo needs to wow us at E3 and some of these features alone are enough to cause a stir. Heres hoping that Nintendo has the games to back up these admittedly exciting rumors.

Here is the original post:

Wii U Getting Achievements And Cloud Saves [Rumor]

WNBA: Catchings, Fever cruise by winless Liberty

INDIANAPOLIS (AP) -- Tamika Catchings scored 16 points to help the Indiana Fever defeat the New York Liberty 91-68 on Saturday night.

Roneeka Hodges scored 15 points, Jeanette Pohlen added 12 and Katie Douglas had 11 for Indiana (4-0). The Fever made 13 of 26 3-pointers while New York made 5 of 17. The Fever made 22 of 27 free throws and committed just 12 turnovers.

Indiana's reserves outscored New York's 52-18.

Plenette Pierson scored 24 points on 10-for-13 shooting for the Liberty (0-5). Cappie Pondexter, New York's leading scorer, finished with 13 points on 4-for-15 shooting. Pierson and Pondexter were the only Liberty players to score in double figures.

New York's past four losses have all been by double digits, by a combined 82 points. The teams play again Sunday at New York.

Indiana, which entered the game as the No. 2 scoring team in the league, shot 47 percent from the field.

The Fever shot just 6-for-19 from the field in the first quarter but made enough free throws to tie the score at 20 by the end of the period.

Indiana heated up in the second quarter making 10 of its 16 shots to take a 49-36 halftime lead. Catchings scored 14 points in the first half and Hodges scored eight off the bench in the second quarter. The Fever made 6-of-13 three-pointers in the first half.

New York cut Indiana's lead to nine points early in the third quarter before the Fever took control. A three-pointer by Shavonte Zellous pushed Indiana's lead to 60-45 and forced the Liberty to call a timeout.

Catchings disagreed with a foul call, then made contact with an official and was issued a technical foul. New York made all three free throws to cut Indiana's lead to 12.

See more here:

WNBA: Catchings, Fever cruise by winless Liberty

Warner to Mount 'Liberty,' Show of Firsts

By RICKY CAMPBELL Register Citizen Staff

TORRINGTON Liberty, an upcoming musical at the Warner Theatre premiering on June 30, is a production of firsts and everyone involved isnt just content with that, but theyre rather excited.

Liberty will showcase the story of an immigrant girl coming from Paris, gathering outside influences ideals of what liberty is to them, and integrating their multiple thoughts into her own development. Its the first time the musical will see the light of day in its entirety, the first time its lead actress will be the focal point in her young career and its the first time Liberty will have the opportunity to push its cast and crew to their ultimate goal: a New York City stage.

On Thursday, cast and crew members of Liberty introduced themselves to Warner staffers, city officials and the public. After explaining the musicals premise, fine details and an opening, teasing number from its lead actress, Liberty cast members hit the stage for their first weekend of rehearsals.

The crew will spend their Thursdays through Saturdays leading up to the June 30 world premiere on the Torrington Main Street theatres stage, practicing their lines and developing their characters. When the show leaves the Warner Theatre after its final performance on July 12, the production, aiming for brighter lights and bigger venues, can look to Torrington as its jumping off point.

For some, it could be the initial catapult to a career under the lights.

For a first gig, this isnt too shabby, lead actress Madeline Brewer said with a smile Thursday following the warm welcome. Brewer, 20, graduated from the American Musical and Dramatic Academy in New York a week ago. Outside of her hometown theater in Pitman, New Jersey, Brewer said shes never landed the lead role.

On June 30, 2012, that will change for Brewer as she becomes the first actress to ever don the copper-turned-green wardrobe of Liberty an immigrant girl from France trying to make a life in 19th century America.

Liberty will hit the stage for the first time, creating a new draw, officials believe, for the different demographics of show-goers.

Youre building a relationship here and that relationship is with the Warner family, Warner Theatre Executive Director John Bonanni said to the group. When you leave, youre going to find yourself missing this place.

Read more from the original source:

Warner to Mount 'Liberty,' Show of Firsts

Fever-Liberty Preview

The Indiana Fever have matched the best start in franchise history.

The New York Liberty are off to their worst start, thanks in part to the Fever.

Indiana looks to set a club record by capitalizing on another matchup with the last-place Liberty and completing a sweep of a home-and-home set Sunday night at Prudential Center.

The Fever (4-0) are trying to prove they're contenders for a WNBA championship after falling to Atlanta in last season's Eastern Conference finals. They're certainly playing like contenders so far in 2012.

Indiana has tied its longest winning streak to open a season, achieved in both 2006 and 2007. Another meeting with New York (0-5) may be just what the Fever need to win a fifth straight.

They had little trouble with the Liberty on Saturday, rolling to a 91-68 home victory. Indiana made 13 of 26 3-pointers and nearly tripled New York in bench points, holding a 52-18 edge.

Indiana has lost its last two road games against the Liberty, including an 87-72 defeat Sept. 17 in Game 2 of the East semifinals. The Fever clinched the series with a victory at home two days later.

Tamika Catchings has totaled 11 points while shooting just 3 of 16 from the field the last two times the Fever have visited the Liberty, including a two-point effort in the playoff matchup.

The reigning WNBA MVP was much better at home against the Liberty on Saturday, scoring 14 of her 16 points in the first half. However, she was issued a technical after making contact with an official while arguing a foul call.

Averaging 19.8 points on the season, Catchings may be in for another strong performance since New York is being outscored by an average of 17.4 points during the worst start to a season in its franchise history.

Read more from the original source:

Fever-Liberty Preview