UCI stem cell researcher to receive $4.8 million in state funding

Public release date: 24-May-2012 [ | E-mail | Share ]

Contact: Tom Vasich tmvasich@uci.edu 949-824-6455 University of California - Irvine

Irvine, Calif., May 24, 2012 A UC Irvine immunologist will receive $4.8 million to create a new line of neural stem cells that can be used to treat multiple sclerosis.

The California Institute for Regenerative Medicine awarded the grant Thursday, May 24, to Thomas Lane of the Sue & Bill Gross Stem Cell Research Center at UCI to support early-stage translational research.

CIRM's governing board gave 21 such grants worth $69 million to 11 institutions statewide. The funded projects are considered critical to the institute's mission of translating basic stem cell discoveries into clinical cures. They are expected to either result in candidate drugs or cell therapies or make significant strides toward such treatments, which can then be developed for submission to the Food & Drug Administration for clinical trial.

Lane's grant brings total CIRM funding for UCI to $76.65 million.

"I am delighted that CIRM has chosen to support our efforts to advance a novel stem cell-based therapy for multiple sclerosis," said Peter Donovan, director of the Sue & Bill Gross Stem Cell Research Center.

MS is a disease of the central nervous system caused by inflammation and loss of myelin, a fatty tissue that insulates and protects nerve cells. Current treatments are often unable to stop the progression of neurologic disability most likely due to irreversible nerve destruction resulting from myelin deficiencies. The limited ability of the body to repair damaged nerve tissue highlights a critically important and unmet need for MS patients.

In addressing this issue, Lane who also directs UCI's Multiple Sclerosis Research Center will target a stem cell treatment that will not only halt ongoing myelin loss but also encourage the growth of new myelin that can mend damaged nerves.

"Our preliminary data are very promising and suggest that this goal is possible," said Lane, a Chancellor's Fellow and professor of molecular biology & biochemistry. "Research efforts will concentrate on refining techniques for production and rigorous quality control of transplantable cells generated from high-quality human pluripotent stem cell lines, leading to the development of the most therapeutically beneficial cell type for eventual use in patients with MS."

Excerpt from:

UCI stem cell researcher to receive $4.8 million in state funding

Di'Anno Wants Former Iron Maiden Bandmate To Undergo Stem Cell Therapy

05/24/2012 . (Classic Rock) Former Iron Maiden singer Paul Di'Anno wants his ex-bandmate Clive Burr to undergo stem cell therapy, despite the costs and risks associated with the procedure.

Burr, the drummer with Maiden from 1979 until 1982, has been in a wheelchair as a result of multiple sclerosis, which has been attacking his nervous system since before he was diagnosed in 2002.

MS reduces the ability of the brain and spinal cord to communicate with each other, resulting in a wide range of potentially severe symptoms. The cause is unknown and there is no cure; but in 2009 researchers made the first breakthrough in reversing symptoms through stem cell therapy.

Di'Anno tells Talking Metal Pirate Radio Burr's condition is "not very good at all." He had a lot to say, read it here.

Classic Rock Magazine is an official news provider for antiMusic.com. Copyright Classic Rock Magazine- Excerpted here with permission.

antiMUSIC News featured on RockNews.info and Yahoo News

...end

Go here to see the original:

Di'Anno Wants Former Iron Maiden Bandmate To Undergo Stem Cell Therapy

His Holiness Paramahamsa Nithyananda Envisions Vedic Revival Through Madurai Aadheenam

Tanjavur, 22 May 2012: Paramahamsa Nithyananda today revealed his dream of an authentic Vedic revival in the new world. He observed that this would happen only if renowned spiritual organizations like the 1500-year-old Madurai Aadheenam played an active role in bringing about this cultural and spiritual renaissance. ...

See the original post here:

His Holiness Paramahamsa Nithyananda Envisions Vedic Revival Through Madurai Aadheenam

SpaceX Dragon capsule arrives at space station

SPACE The privately bankrolled Dragon capsule arrived at the International Space Station for a historic docking Friday, captured by astronauts wielding a giant robot arm.

It succeeded in making the first commercial delivery into the cosmos.

U.S. astronaut Donald Pettit used the space station's 58-foot robot arm to snare the gleaming white Dragon after a few hours of extra checks and maneuvers. The two vessels came together while sailing above Australia.

"Looks like we've got us a dragon by the tail," Pettit announced from 250 miles up once he locked onto Dragon's docking mechanism.

"You've made a lot of folks happy down here over in Hawthorne and right here in Houston," radioed NASA's Mission Control. "Great job guys."

NASA controllers clapped as their counterparts at SpaceX's control center in Hawthorne, Calif. -- including SpaceX's billionaire maestro, Elon Musk, of PayPal fame -- lifted their arms in triumph and jumped out of their seats to exchange high fives.

This is the first time a private company has attempted to send a vessel to the space station, an achievement previously reserved for a small, elite group of government agencies. And it's the first U.S. craft to visit the station since the final shuttle flight last July.

The astronauts wasted no time getting the Dragon capsule into position for actual docking to the space station. The unmanned capsule is carrying 1,000 pounds of supplies on this unprecedented test flight.

On Thursday, the capsule came within 1 1/2 miles of the space station in a practice fly-by. It returned to the neighborhood early Friday so Pettit, along with Dutch astronaut Andre Kuipers could capture it with a robot arm. First, the capsule went through a series of stop-and-go demonstrations to prove it was under good operating control.

NASA ordered extra checks of the Dragon's imaging systems as the capsule drew ever closer to the space station, putting the entire operation slightly behind schedule. At one point, SpaceX controllers ordered a retreat because of a problem with on-board tracking sensors.

Read the original post:

SpaceX Dragon capsule arrives at space station

SpaceX Dragon capsule docks with space station

CAPE CANAVERAL, Florida (Reuters) - Astronauts aboard the International Space Station captured Space Exploration Technologies' Dragon cargo ship and guided it into a berth on Friday, docking the first privately owned vehicle to reach the orbital outpost. Using the station's 58-foot long (17.7-meter) robotic crane, NASA astronaut Don Pettit snared Dragon at 9:56 a.m. EDT (1356 GMT) as the two ...

Go here to read the rest:

SpaceX Dragon capsule docks with space station

Space Station astronauts capture Dragon capsule, make history

SpaceX, the upstart California rocket maker, launched a new era in spaceflight this morning when its Dragon capsule was captured by the International Space Station, concluding a cargo delivery trip previously made only by NASA space shuttles and other governments' spacecraft.

At 9:56 a.m. EDT, space station flight engineer Don Pettit reached out with a 58-foot robotic arm and grabbed the unmanned capsule, which was "free drifting" beneath the $100-billion station at 17,000 miles an hour, roughly 250 miles above northwest Australia.

"Houston, it looks like we got us a Dragon by the tail," Pettit declared. "We're thinking this went really well."

The capture came quickly, after two hours of delay and as NASA, the space station astronauts and SpaceX, the 10-year-old rocket company founded by billionaire Elon Musk, were contemplating another delay.

They had intended to wait until the station and Dragon were on the day-side of Earth, to make the grab in full sunlight. But shortly before 10 a.m., they decided to settle for dawn, which lit up the Dragon and the robotic arm while the Earth below remained dark.

Minutes later, NASA TV showed the robotic arm carrying Dragon across a bright Earth backdrop.

"Once again SpaceX has done it. They have become the first private company to successfully launch their own spacecraft and get it captured by the International Space Station's robotic arm," said NASA commentator Josh Byerly.

NASA TV then turned to the celebrations: hugs all around at SpaceX's Mission Control room in Hawthorne, Calif., and handshakes at NASA's Mission Control room at Johnson Space Center in Houston.

Over the next several hours, U.S. astronauts Pettit and Joe Abaca, as well as flight engineer Andres Kuipers of The Netherlands, will use the robotic arm to slowly reel in the 7,300-pound spacecraft and its half-ton of supplies and mate it to a portal in the space station's Harmony module. Then the astronauts will connect power and communication cables. They hope to be done by 5 p.m.

Hatches, though, won't be opened until Saturday morning. At that time, the ISS astronauts, who also include three Russians, will unload 1,146 pounds of food, clothing, supplies and science experiment kits delivered by SpaceX. Then they will reload Dragon with about 1,455 pounds of science experiment kits, trash and personal items to go back to Earth.

View post:

Space Station astronauts capture Dragon capsule, make history

Success! Space station snags SpaceX Dragon capsule

An astronaut using the International Space Station's robot arm successfully plucks a commercial cargo ship out of open space to complete a dramatic rendezvous.

Gotcha! The robotic arm of the International Space Station captures the Dragon capsule.

In a moment of high drama on the high frontier, flight engineer Donald Pettit, operating the International Space Station's robot arm, this morning reached out and locked onto SpaceX's Dragon capsule.

That capture of the commercial cargo ship came after a complex rendezvous, a final sequence of approach-and-retreat test maneuvers and quick work to adjust critical sensors that were getting fooled by reflections from a Japanese research module.

The last-minute hiccups were just that, relatively minor adjustments to correct for the real-world performance of complex laser and infrared imagers used to compute the Dragon cargo ship's velocity and distance from the station.

The SpaceX Dragon cargo ship as seen from the International Space Station Friday, poised just below the lab complex awaiting capture by the station's robot arm.

But like everything in the world of manned spaceflight, where the stakes are high and the margins for error small, flight controllers in Houston and at SpaceX's Hawthorne, Calif., control center took their time, inserting additional checks to make sure everything was working properly.

Now running well behind schedule, flight controllers left it up to Pettit as to whether he felt comfortable grappling the spacecraft in orbital darkness or would prefer delaying to the next daylight pass depending on lighting conditions. When all was said and done, the crew was about two hours behind schedule when the Dragon completed its approach, halting at a designated capture point 30 feet directly below the lab complex.

As the huge space station and the diminutive cargo craft flew in tandem at 5 miles per second, Pettit, working inside the lab's multi-window cupola module, decided to press ahead in orbital darkness, guiding the arm's latching end effector onto a grapple fixture on the side of the cargo ship at 9:56 a.m. EDT (GMT-4). Internal snares were tightened to secure the spacecraft to the arm, completing a rendezvous that began with Dragon's launch Tuesday from the Cape Canaveral Air Force Station.

Like a bird swooping to its perch, the Dragon cargo ship moves into position for capture at the International Space Station.

See original here:

Success! Space station snags SpaceX Dragon capsule

NASA | Incandescent Sun – Video

23-05-2012 13:34 This video takes SDO images and applies additional processing to enhance the structures visible. While there is no scientific value to this processing, it does result in a beautiful, new way of looking at the sun. The original frames are in the 171 Angstrom wavelength of extreme ultraviolet. This wavelength shows plasma in the solar atmosphere, called the corona, that is around 600000 Kelvin. The loops represent plasma held in place by magnetic fields. They are concentrated in "active regions" where the magnetic fields are the strongest. These active regions usually appear in visible light as sunspots. The events in this video represent 24 hours of activity on September 25, 2011. This video is public domain and can be downloaded at: Like our videos? Subscribe to NASA's Goddard Shorts HD podcast: Or find NASA Goddard Space Flight Center on Facebook: Or find us on Twitter:

Continued here:

NASA | Incandescent Sun - Video

Pioneering U.S. commercial spaceflight quiets critics

CAPE CANAVERAL, Florida (Reuters) - A pioneering commercial spaceship closed in on the International Space Station on Wednesday, a key test in a controversial program to reduce the U.S. government's role in human space flight. Space Exploration Technologies, or SpaceX, launched its Dragon cargo capsule into orbit on Tuesday from Cape Canaveral Air Force Station in Florida for a test run to the ...

Link:

Pioneering U.S. commercial spaceflight quiets critics

Liquid Oxygen Piston Pump Ready for Reusable Space Flight

MOJAVE, Calif., May 24, 2012 /PRNewswire/ -- XCOR announced today that it has achieved a key technical milestone with its flight weight rocket piston pump hardware. XCOR engineers have successfully and repeatedly pumped liquid oxygen (LOX) at flow rates required to supply the Lynx suborbital vehicle main engines. Combined with earlier demonstrated kerosene pumps and fully characterized engines, XCOR is now poised for main propulsion integration into the Lynx flight weight fuselage.

(Photo: http://photos.prnewswire.com/prnh/20120524/LA13236)

XCOR's family of rocket piston pumps and engines now includes and is suitable for: kerosene, LOX, liquid hydrogen (LH2), and liquid methane. These piston pumps are a critical component for safe, cost-effective, sustainable, reliable and highly reusable rocket engines for XCOR's Lynx and other launchers including upper stage liquid hydrogen engines suitable for the Atlas V, Delta IV, and the planned NASA Space Launch System (SLS).

"For propulsion from 50 to 75,000 lbf thrust, XCOR's proprietary combined thermodynamic cycle for piston pumps is ideal," said XCOR CEO Jeff Greason. "Unlike a turbo pump used in traditional rocket engines, the development cost of a piston pump is much lower and the useful range of thrust is much higher without modification. Manufacturability is easier, and reliability is considerably higher. The maintenance cycle is closer to that of an automotive engine rather than 'disassemble and inspect after every flight' required with conventional turbo fed systems. This technology is integrated into the LOX/kerosene propulsion system on our Lynx suborbital launch vehicle, and will be applied to future main propulsion 30,000 lbf thrust LOX/LH2 engines currently under development."

"The ability to ensure low cost and easy, repeatable manufacturing of critical pump technology over a 30 to 40 year product lifecycle is a major factor in why we chose this piston pump technology," said Andrew Nelson, XCOR Chief Operating Officer. "This technology is also tightly coupled with certain design decisions regarding manufacturability of our rocket engine chambers and nozzles. Other rocket engines, nozzles and turbo pumps require time consuming, exotic manufacturing processes, specialty equipment and large cadres of artisan technicians and engineers to assemble and maintain them. XCOR rocket engines, nozzles and piston pumps can be manufactured by a skilled industrial machine shop and may be assembled by a streamlined workforce and tested with mobile equipment, eliminating fixed test hardware, facilities, and personnel. Our customers recognize in our technology the ability to contain the costs of developing, extending and maintaining a propulsion system over several decades."

"At these thrust classes, the weight is comparable to and potentially lighter than a turbo pump system when the entire propulsion package is taken into account," said XCOR chief engineer Dan DeLong. "The fuel and oxidizer pump also enables a variety of other innovations, such as our lightweight, highly manufacturable aluminum nozzles. Our pumps are fabricated using readily available automotive manufacturing techniques developed over the past 120 years. This allows us to competitively procure high quality components while avoiding the overhead of maintaining a specialized industrial base. This is our fifth generation piston pump; the first generation was internally funded, DARPA helped on the second. XCOR developed internally the pump that eventually went on the X-Racer which was the first designed and optimized for low manufacturing cost. This latest generation is almost 20 times more powerful than the X-Racer pump, but it's only twice the weight. After more than ten years work, I think we're getting good at this."

"The fielding of the LOX pump is a major milestone for XCOR, the Lynx, our wet lease customers and our engine customers," said Nelson, "I can't wait to see it powering our engines later this summer!"

XCOR Aerospace is a California corporation located in Mojave, California. The company is in the business of developing and producing safe, reliable and reusable rocket powered vehicles, propulsion systems, advanced non-flammable composites and other enabling technologies like rocket piston pumps that enable full reusability. XCOR is working with aerospace prime contractors and government customers on major propulsion systems, and concurrently building the Lynx, a piloted, two-seat, fully reusable, liquid rocket powered vehicle that takes off and lands horizontally. The Lynx-family of vehicles serves three primary missions depending on their specific type including: research & scientific missions, private spaceflight, and micro satellite launch (only on the Lynx Mark III). The Lynx production models (designated Lynx Mark II) are designed to be robust, multi-mission (research / scientific or private spaceflight) commercial vehicles capable of flying to 100+ km in altitude up to four times per day and are being offered globally on a wet lease basis. (www.xcor.com).

Read the original here:

Liquid Oxygen Piston Pump Ready for Reusable Space Flight

Space X craft makes historic connection with space station

A private spacecraft docked with the International Space Station on Friday, a milestone in a new era of commercial space flight.

The docking happened just before 10 a.m. ET, almost two hours later than planned, when the station's robotic arm captured the unmanned SpaceX Dragon spacecraft.

"Looks like we caught a Dragon by the tail," astronaut Don Pettit said after capturing the capsule with the robotic arm, according to NASA.

The Dragon capsule launched Tuesday from Cape Canaveral, Florida, carrying food, clothing, 22 pounds of computer equipment, 46 pounds of supplies for science experiments, and other cargo.

NASA said it authorized the flight after Dragon successfully completed all tests in preparation for docking and the space station mission management team completed a thorough review of its progress.

Connecting to the space station required NASA's approval in a staged approach that SpaceX called "the most difficult aspects of the mission."

The mission, hailed by NASA Administrator Charles Bolden as a step toward a new future of private innovation in the space industry, comes as government funding of the space program decreases in an era of fiscal austerity.

Dragon was carried into orbit by the Falcon 9 rocket. Dragon then orbited the Earth on Tuesday and Wednesday, "firing its thrusters to catch up to the space station," SpaceX said.

The space station crew plans to open Dragon's hatch Saturday, it said.

Under the mission plan, Dragon will remain attached to the space station for two weeks before it plummets back into the atmosphere and splashes into the Pacific Ocean off the California coast, according to SpaceX.

See the article here:

Space X craft makes historic connection with space station

Private spacecraft SpaceX Dragon docks with space station

SpaceX Dragon berths with ISS

STORY HIGHLIGHTS

(CNN) -- A private spacecraft connected to the International Space Station on Friday, a milestone in a new era of commercial space flight.

It happened just before 10 a.m. ET when the station's robotic arm captured the unmanned SpaceX Dragon spacecraft. The process of attaching the Dragon to the space station was completed at 12:02 p.m. ET.

The process began almost two hours later than planned while engineers fixed part of the radar system aboard the Dragon that measured distance to the space station, NASA said.

"Looks like we caught a Dragon by the tail," astronaut Don Pettit said after capturing the capsule with the robotic arm, according to NASA.

Ashes of 'Star Trek' actor on private rocket

The next step is for the Dragon capsule to unload its cargo, which includes food, clothing, 22 pounds of computer equipment and 46 pounds of supplies for science experiments.

"There's so much that could've gone wrong and it went right," said SpaceX founder Elon Musk, the founder of PayPal, who earlier called the successful capture "awesome."

NASA's space station program manager Mike Suffredini said the spacecraft performed "nearly flawlessly." He said SpaceX did a "fantastic job" in designing and operating the Dragon.

Follow this link:

Private spacecraft SpaceX Dragon docks with space station

Mission a step toward future of private innovation in space industry

LIVE: Private spacecraft docks with space station

A private spacecraft connected to the International Space Station on Friday, a milestone in a new era of commercial space flight.

It happened just before 10 a.m. ET when the station's robotic arm captured the unmanned SpaceX Dragon spacecraft. The process of attaching the Dragon to the space station was completed at 12:02 p.m. ET.

The process began almost two hours later than planned while engineers fixed part of the radar system aboard the Dragon that measured distance to the space station, NASA said.

"Looks like we caught a Dragon by the tail," astronaut Don Pettit said after capturing the capsule with the robotic arm, according to NASA.

The next step is for the Dragon capsule to unload its cargo, which includes food, clothing, 22 pounds of computer equipment and 46 pounds of supplies for science experiments.

"There's so much that could've gone wrong and it went right," said SpaceX founder Elon Musk, the founder of PayPal, who earlier called the successful capture "awesome."

NASA's space station program manager Mike Suffredini said the spacecraft performed "nearly flawlessly." He said SpaceX did a "fantastic job" in designing and operating the Dragon.

The Dragon capsule launched Tuesday from Cape Canaveral, Florida. NASA said it authorized the flight after Dragon completed all tests in preparation for reaching the space station and the station mission management team completed a thorough review of its progress.

Connecting to the space station required NASA's approval in a staged approach that SpaceX called "the most difficult aspect of the mission."

Visit link:

Mission a step toward future of private innovation in space industry

Space station catches 'a Dragon'

SpaceX Dragon berths with ISS

STORY HIGHLIGHTS

(CNN) -- A private spacecraft connected to the International Space Station on Friday, a milestone in a new era of commercial space flight.

It happened just before 10 a.m. ET when the station's robotic arm captured the unmanned SpaceX Dragon spacecraft. The process of attaching the Dragon to the space station was completed at 12:02 p.m. ET.

The process began almost two hours later than planned while engineers fixed part of the radar system aboard the Dragon that measured distance to the space station, NASA said.

"Looks like we caught a Dragon by the tail," astronaut Don Pettit said after capturing the capsule with the robotic arm, according to NASA.

Ashes of 'Star Trek' actor on private rocket

The next step is for the Dragon capsule to unload its cargo, which includes food, clothing, 22 pounds of computer equipment and 46 pounds of supplies for science experiments.

"There's so much that could've gone wrong and it went right," said SpaceX founder Elon Musk, the founder of PayPal, who earlier called the successful capture "awesome."

NASA's space station program manager Mike Suffredini said the spacecraft performed "nearly flawlessly." He said SpaceX did a "fantastic job" in designing and operating the Dragon.

Original post:

Space station catches 'a Dragon'