Nanotechnology Now an Unseen Success

To battle tough performance gear competitors like The North Face, Dicks Sporting Goods

Consumers want more juice for the squeeze, explains Shian-Li McGuire, a brand manager at Dicks Sporting Goods. Hard-core sports enthusiasts, she adds, are especially pushing fabric innovation. So last year, the company hired a fabric specialist, who searches for new ways to manipulate fabrics.

Source: Micron

World's highest capacity NAND flash memory die, developed by Micron and Intel.

Across the country, Boise, Idaho-based chipmaker Micron

Without this technology, there would be no place for us, says Dean Klein, vice president of memory system development at Micron. We make the worlds most advanced chips.

Micron has spent billions of dollars creating fabrication rooms where chips are built.

Consumer goods companies have it easier than Micron. Some nanotechnology research labs and upstarts are supplying resins and chemicals that contain nanotechnology. For example Nano-Tex, which supplies Aquapel to Dicks Sporting Goods and other companies, sells chemicals that coat fabric.

Creating buzzworthy new products in crowded marketplaces is a must-do goal these days. So apparel makers like Eddie Bauer and Dockers, a unit of Levi Straus, count on nanotechnology to add strength, durability or other performance properties to their fabrics.

The tiny, powerhouse technology is also being harnessed in key industries like energy, building and construction, high-tech, paints and medical device industries.

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Nanotechnology Now an Unseen Success

New ISO Technical Report Guides Characterization of Nanomaterials in Toxicology

New ISO Technical Report Guides Characterization of Nanomaterials in Toxicology U.S. Leadership Supports Development of Newly Released International Guidelines New York May 29, 2012

ISO TR 13014:2012 was prepared by ISO TC 229, Nanotechnologies, Working Group (WG) 3, Health, Safety and Environment, under the project leadership of Dr. Richard Pleus of the United States. This group is U.S.-led, operating under the leadership of Dr. Laurie Locascio of the National Institute of Standards and Technology (NIST). Dr. Vladimir Murashov of the National Institutes of Occupational Safety and Health (NIOSH) serves as the WG 3 chair for the U.S. Technical Advisory Group (TAG) to ISO TC 229, which is accredited and administered by the American National Standards Institute (ANSI).

By understanding the chemical and physical characteristics of nano-objects, we are working to decrease toxicity of materials and promote the development of safer alternatives, said Dr. Pleus. The work done in this document has a fundamental importance in toxicology, as it tells scientists the material being tested needs to be understood: What does it look like? What is it made of? How does it interact with the surrounding environment?

Nanotechnology, which refers to the manipulation and control of matter in the nanoscale (approximately 1 to 100 nm), is revolutionizing virtually all industry sectors, from information technology to medicine to clean energy production. The ANSI-administered U.S. TAG to ISO TC 229 is responsible for formulating all U.S. positions and proposals with regard to ISO standardization in the field of nanotechnology.

The U.S. has been an active participant and effective leader within ISO TC 229 since the formation of the committee in 2005, playing a key role in influencing the strategic and technical direction of the committees standardization initiatives, said Fran Schrotter, senior vice president and chief operating officer at ANSI.

Participation on the U.S. TAG to ISO TC 229 is open to all materially affected U.S. national interested parties. For more information, visit http://www.ansi.org/isotc229tag or contact the TAG administrator, Heather Benko (hbenko@ansi.org).

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New ISO Technical Report Guides Characterization of Nanomaterials in Toxicology

Medical school cleaners secure London living wage

Medical school cleaners secure London living wage

7:40am Tuesday 29th May 2012 in News By Alexandra Rucki

Campaigning cleaners were celebrating after securing a pay increase up to the London living wage.

The cleaners for St George's Hospital Medical School, housed within St George's Hospital, Tooting, have been running a campaign for increased pay through posters, leafleting and petitions.

They will be paid a new hourly rate of 8.30 per hour from August 1, an increase from their current wage of 6.08 an hour after UNISON signed a deal with contractors Ocean Contract Cleaning Ltd.

However, trade union Industrial Workers for the World (IWW) have said the cleaners could face having their hours cut, which would make the pay rise futile.

UNISON have denied signing anything agreeing to cuts, with a spokesperson accusing IWW of being an anarchist group.

A protest to raise awareness of the issue was staged by IWW outside St George's Hospital last Friday, May 25.

Cleaners, medical students and families took part to raise awareness staff were being paid below the London wage.

A spokesperson for UNISON said: "We managed to secure the London living wage for hospital staff, but never for the teaching school.

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Medical school cleaners secure London living wage

Duke-NUS Medical School Marks Second Graduation

The second class of DukeNUS Graduate Medical School (Duke-NUS) students marked the completion of their fouryear Doctor of Medicine (M.D.) training today. Mr. Heng Swee Keat, Singapores Minister for Education, graced the schools pregraduation celebration held in the auditorium of the Yong Siew Toh Conservatory of Music at the National University of Singapore. The distinguished Professor Sydney Brenner, Nobel Laureate in Medicine 2002, was the event's keynote speaker.

This cohort of DukeNUS graduands will further receive training as postgraduate year one doctors who will provide clinical care as vital members of the healthcare team. They may be trained under the Residency Programmes in specialties such as Internal Medicine, Emergency Medicine, Family Medicine, Obstetrics and Gynaecology, Ophthalmology, Orthopaedic Surgery, Otorhinolaryngology, Paediatrics and Psychiatry, among other fields.

Mr Heng Swee Keat, Minister for Education, said: With its intensive focus on research and its unique feature of taking in graduate-entry students from a variety of academic backgrounds, but who share a common passion of serving others, Duke-NUS produces doctors with a diversity of insights and perspectives, and brings together different strengths and expertise to continually innovate and improve on the healthcare provision for Singaporeans.

Professor Tan Chorh Chuan, NUS President, said: Today, we celebrate with pride the remarkable accomplishments of Duke-NUS Class of 2012. Over the last four years, these students have been immersed in the Duke-NUS culture of excellence, boldness and imagination; and they have benefitted greatly from the innovative clinical and research training. The rigorous training and exposure will enable our graduands to make a real difference to patients, our community and society. We are confident these graduands will become role models for future generations of clinicians and clinician-scientists who will transform medicine through research and innovation. My heartiest congratulations to the Class of 2012!

It is clear that the innovative approach to medical education, clinical and basic research embodied by Duke-NUS is producing an extraordinary calibre of clinician-scientists who are uniquely equipped to become the healthcare and research leaders of the future, said Dr. Victor J. Dzau. Never before has there been as great a need for clinician-scientists who can not only engage in discovery science, but can translate discoveries from the laboratory to the clinic and improve the health of patients and the community. I have great pride and expectations for the class of 2012. Dr. Victor J. Dzau, Chancellor for Health Affairs, Duke University, and CEO, Duke University Health System, was in Singapore to grace the hooding ceremony.

I am proud to see that our graduands are starting a new chapter in their lives. They will work as critical members of clinical healthcare teams, to bring hope and relief to patients and their families. We hope they will continue to let their passion for medicine and their spirit of inquiry and curiosity drive future discoveries in patient and disease management, said Professor Ranga Krishnan, Dean of the DukeNUS.

Duke-NUS had five annual intakes since its M.D. programme started in August 2007. Since then, the school has admitted more than 240 post-baccalaureate students into its Americanstyled, researchoriented, four-year medical school programme. These students come from a diverse range of local and international undergraduate institutions. These include: National University of Singapore, Nanyang Technological University, Fudan University, Shanghai Jiao Tong University, Peking University, Chinese University in Hong Kong, University of Mumbai, University of Philippines, University of Oxford, University of Cambridge, Johns Hopkins University, Yale University, Duke University, Harvard University, and others.

The DukeNUS graduands will receive a joint Duke and NUS M.D. degree at the NUSCommencement Ceremony on 7 July 2012.

In addition to its 240-strong M.D. cohort, the school has over 20 students in itsPhD programme track. This track enables research-oriented medical students to leverage on their biomedicine knowledge to spur translational research aimed at developing better patient treatment, strategies and technology.

Duke-NUS Class of 2012 - Graduation Celebration & Hooding Ceremony, May 26, 2012

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Duke-NUS Medical School Marks Second Graduation

Supervisors approve $35 million deal with Caribbean medical school

BY KELLIE SCHMITT Californian staff writer kschmitt@bakersfield.com Tuesday, May 29 2012 03:26 PM

Kern County supervisors unanimously approved a unique proposal to give Ross University in the Caribbean the vast majority of Kern Medical Center's student rotation slots in exchange for $35 million over 10 years.

"This provides KMC and Ross the ability to enhance their program offerings," said Supervisor Ray Watson. "In the long term, this will be good for the health of Kern County. I think it's a step forward both financially and in terms of the education we can provide."

The new arrangement will give Ross, which is located on the island of Dominica, about 100 medical school rotations. Medical students typically spend their first two years focusing on academics and their last two rotating through hospitals to learn clinical expertise under close supervision.

They are different from the residents at KMC, who study a specialty there after graduating from medical school.

While California-based medical schools have affiliations with nearby hospitals that allow free student rotations, Caribbean schools often pay to allow their students to train in the United States.

It's tough for offshore schools like Ross to secure rotations in U.S. hospitals, especially in California, the home of nearly 18 percent of its students. That's why officials were willing to dole out $35 million, the highest amount the school has ever offered a hospital for rotations, officials said.

"We thought we could provide something good for U.S. students and the community," said Ross Dean Joseph Flaherty.

While Caribbean schools have a reputation for attracting students who can't get in to U.S. schools, KMC CEO Paul Hensler said Ross' test scores and students are highly competitive; there just aren't enough medical school slots nationwide.

And, since there likely won't be a medical school in the Central Valley anytime soon, a close affiliation with a top Caribbean school is a good option for funneling physicians into Kern County, Hensler said.

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Supervisors approve $35 million deal with Caribbean medical school

Biostem U.S., Corporation Appoints Philip A. Lowry, MD as Chairman of Its Scientific and Medical Board of Advisors

CLEARWATER, FL--(Marketwire -05/29/12)- Biostem U.S., Corporation, (HAIR.PK) (HAIR.PK) (Biostem, the Company), a fully reporting public company in the stem cell regenerative medicine sciences sector, today announced that Philip A. Lowry, MD, has been appointed as the Chairman of its Scientific and Medical Board of Advisors (SAMBA).

According to Biostem CEO, Dwight Brunoehler, "As Chairman, Dr. Lowry will work with a team drawn from a cross-section of medical specialties. His combination of research, academic and community practice experience make him the perfect individual to coordinate and lead the outstanding group of physicians that makes up our SAMBA. As a group, The SAMBA will guide the company to maintain the highest ethical standards in every effort, while seeking and developing new cutting edge technology based on stem cell use. I am privileged to work with Dr. Lowry, once again."

Dr. Lowry stated, "Dwight is an innovative businessman with an eye on cutting-edge stem cell technology. His history in the industry speaks for itself. I like the plan at Biostem and look forward to working with everyone involved."

Dr. Philip A. Lowry received his undergraduate degree from Harvard College before going on to the Yale University School of Medicine. His completed his internal medicine residency at the University of Virginia then pursued fellowship training in hematology and oncology there as well. During fellowship training and subsequently at the University of Massachusetts, he worked in the laboratory of Dr. Peter Quesenberry working on in vitro and in vivo studies of mouse and human stem cell biology.

Dr. Lowry twice served on the faculty at the University of Massachusetts Medical Center from 1992-1996 and from 2004-2009 as an assistant and then associate clinical professor of medicine establishing the bone marrow/stem cell transplantation program there, serving as medical director of the Cryopreservation Lab supporting the transplant program, helping to develop a cord blood banking program, and teaching and coordinating the second year medical school course in hematology and oncology. Dr. Lowry additionally has ten years experience in the community practice of hematology and oncology. In 2010, Dr. Lowry became chief of hematology/oncology for the Guthrie Health System, a three-hospital tertiary care system serving northern Pennsylvania and southern New York State. He is charged with developing a cutting-edge cancer program that can project into a traditionally rural health care delivery system.

Dr. Lowry has also maintained a career-long interest in regenerative medicine springing from his research and practice experience in stem cell biology. His new role positions him to foster further development of that field. As part of a horizontally and vertically integrated multi-specialty team, he is closely allied with colleagues in cardiology, neurology/neurosurgery, and orthopedics among others with whom he hopes to stimulate the expansion of regenerative techniques.

About Biostem U.S., Corporation

Biostem U.S., Corporation is a fully reporting Nevada corporation with offices in Clearwater, Florida. Biostem is a technology licensing company with proprietary technology centered on providing hair re-growth using human stem cells. The company also intends to train and license selected physicians to provide Regenerative Cellular Therapy treatments to assist the body's natural approach to healing tendons, ligaments, joints and muscle injuries by using the patient's own stem cells. Biostem U.S. is seeking to expand its operations worldwide through licensing of its proprietary technology and acquisition of existing stem cell-related facilities. The company's goal is to operate in the international biotech market, focusing on the rapidly growing regenerative medicine field, using ethically sourced adult stem cells to improve the quality and longevity of life for all mankind.

More information on Biostem U.S., Corporation can be obtained through http://www.biostemus.com, or by calling Fox Communications Group 310-974-6821.

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Biostem U.S., Corporation Appoints Philip A. Lowry, MD as Chairman of Its Scientific and Medical Board of Advisors

Personality Traits May Determine How Long A Person Lives

Editor's Choice Main Category: Psychology / Psychiatry Article Date: 29 May 2012 - 12:00 PDT

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After evaluating the personalities of 243 individuals aged 100+ (centenarians), the team found that the majority shared similar personality traits, such as being optimistic, easygoing, outgoing, staying engaged in activities and enjoying laugher. These findings indicate that these types of traits may contribute to longevity.

The study is published online in the journal Aging. The researchers findings derive from Einstein's Longevity Genes Project, which includes more than 500 Ashkenazi (Eastern European) Jews aged 95+ as well as 700 of their children. The team selected Ashkenazi Jews as they are genetically homogeneous, this making it easier for the researchers to detect genetic variations.

Results from earlier studies have suggest that personality comes from underlying genetic mechanisms that may directly impact health. In this study, the team developed a brief measure (the Personality Outlook Profile Scale [POPS]) of personality in centenarians, in order to identify genetically-based personality characteristics of 243 centenarians.

Nir Barzilai, M.D., the Ingeborg and Ira Leon Rennert Chair of Aging Research, director of Einstein's Institute for Aging Research and co-corresponding author of the study, explained:

Furthermore, the team found that the centenarians had higher scores for being conscientious and lower scores for displaying neurotic personality compared with a representative sample of the U.S. population.

Dr. Barzilai said:

Written By Grace Rattue Copyright: Medical News Today Not to be reproduced without permission of Medical News Today

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Personality Traits May Determine How Long A Person Lives

Extroverts live longer, study of centenarians suggests

ByJennifer Welsh LiveScience

The more outgoing and optimistic you are, the longer you may live, a new study suggests. Researchers have found that personality traits like being outgoing, optimistic, easygoing, and enjoying laughter as well as staying engaged in activities may be an important part of the longevity genes mix.

"When I started working with centenarians, I thought we'd find that they survived so long in part because they were mean and ornery," study researcher Nir Barzilai, of the Albert Einstein College of Medicine, said in a statement. "But when we assessed the personalities of these 243 centenarians, we found qualities that clearly reflect a positive attitude towards life."

The study is a part of the Albert Einstein College of Medicine's Longevity Genes Project, which includes more than 500 Ashkenazi Jews ages 95 and older, and 700 of their kids. This small subset of Eastern European Jews is genetically very similar to each other. In addition, some members of the population are extremely long-lived, so it's easy to compare their genes to the genetics of members of the population who don't fall into that category. [ 7 Ways the Mind & Body Change With Age ]

By analyzing the genes of these people, researchers are discovering why some of them live so long, and others don't.

Previous studies of this population have found other genetic reasons for their longevity, including genes related to cellular repair mechanisms. Another study found that these centenarians don't necessarily behave any better than the general population when it comes to health habits: They smoke, drink and eat just as badly as the rest of us.

So why look at personality? A person's level of shyness or how open they are to new experiences, say, arise from underlying genetic mechanisms, which may also affect health, the researchers said. So Barzilai and colleagues developed a brief measure of personality, which they gave to 243 of the centenarians in the study (average age 97.6 years, 75 percent women).

"Most were outgoing, optimistic and easygoing," Barzilai said of the centenarians. "They considered laughter an important part of life and had a large social network. They expressed emotions openly rather than bottling them up."

In addition, the centenarians had lower scores for displaying neurotic personality and higher scores for being conscientious compared with a representative sample of the U.S. population.

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Integrative Medicine Part IV – Preventive Aging

Does old age necessarily mean declining health and cognition or can one age gracefully with a high quality of life?

This was another topic discussed at the recent Health and Wellness conference organized by the University of Maryland Center for Integrative Medicine. Steven Gambert, MD, Professor of Medicine and Surgery and Director of Geriatric Medicine at the University of Maryland Medical Center described preventive aging. Here are my notes from his talk with some personal observations added in.

America has a rapidly aging population. In 1900 only 4% were over age 65 and 1% over 75 years. By 1950, it was 8% and 2.6% respectively and by 2000 it was 13% and 5% with these expected to grow to 21% and 8% by 2030. In absolute numbers, there are now about 12 million over the age of 80; a doubling since 1957. Older people run the full gamut from the very healthy, to those with a few health issues, to those with multiple problems to the very frail. Frail individuals (see my earlier post of frailty) have a high risk for poor outcomes of any illness, slower recovery and heightened mortality. So the agenda, of course, is to stay as healthy as possible throughout your later years. Can you do anything to prevent illness? Can you embark on a preventive aging program? The answer is definitively yes and it is never too late to get started. But just like saving up for retirement, its best to begin at an early age so that the value can compound through the years.

The first major element of the preventive aging program is to prevent an acceleration of the normal aging process. Most physiologic functions begin a slow but steady decline beginning at about age 30 to 35. This includes our bone density, kidney and lung function and cognitive skills. Some decline is inevitable but the process can be slowed. There are four basic steps.

In no particular order the first step is to avoid environmental risk. It is never too late to stop smoking and so reduce the risk of lung cancer and other cancers but also to slow the decline of general lung function. Noise is an environmental hazard. Hearing declines with age and noise rapidly accelerates that decline. Loud music and loud restaurants are best avoided despite our current cultural attractions to both.

The second step is proper nutrition. Eating foods with a wide mix of vitamins and minerals, high quality protein in sufficient quantity, good oils and fats and lots of fiber is of critical importance. Vitamin and mineral supplements are still valuable but they should be just that supplements not the prime source.

The third step is exercise. Our muscles were meant to be used and we need to do just that. A regular regimen of moderate aerobic exercise such as walking for 30 minutes each day cant be beat. Add to that some weight bearing exercise (probably at a gym or similar facility) three times each week to maintain and build strength. And remember to do both range of motion such as simple stretching or adding in yoga and balance exercises regularly.

The fourth and very critical step to prevent acceleration of normal aging is to exercise your brain. Do some activities that challenge your mind Sudoku or chess does that; watching TV definitely does not!

Following these four steps can dramatically slow the aging process but you next need to prevent age prevalent diseases. Here again the best time to do this begins when you are young. The leading causes of death in the elderly are heart disease, cancer and stroke no surprise here. Each of these are largely but not entirely preventable by attending to our lifestyles. Unfortunately most Americans eat a non-nutritious diet and too much of it, dont get enough exercise, are chronically stressed and 20% smoke. The result is a population which is obese, with high blood pressure, an actual developing epidemic of diabetes and over time a high incidence of heart disease, cancer and stroke. So it behooves us to address our lifestyles beginning at whatever age we may be today and following though over the years.

In addition older people should be sure that their immunizations are up-to-date such as annual influenza in addition to the pneumonia vaccine and shingles vaccine but also the less commonly paid attention ones such as tetanus and diphtheria. And as already suggested, avoid high noise environments, eat a good diet, get regular exercise and use your brain regularly.

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Integrative Medicine Part IV – Preventive Aging

Cynthia Rothschild: Oh, the Drama! The UN Human-Rights System Tackles Sexual Orientation and Gender Identity

The United Nations hosted its first-ever high-level panel on violence and discrimination based on sexual orientation and gender identity in early March. Convened by the government of South Africa, some, including me, would argue that this event is at least 10 years overdue. Nonetheless, seeing Ban Ki Moon, the Secretary General of the U.N., in an opening video statement uneqivocally offer his support in this struggle was extraordinary:

I've been doing LGBT human-rights work for two decades, and this was probably the "gayest," or certainly the most theatrical, U.N. moment I've encountered. As house lights lowered within the U.N. Human Rights Council in Geneva, strips of lighting on hundreds of desks in the room cast an eerie florescent glow. The ceiling, a three-dimensional, wildly colored, apocalyptic landscape, was set in emergency-lighting haze as a giant, onscreen Secretary General implored states to address and prevent violations. Pretty moving stuff, actually. With many LGBT- and sexual-rights activists attending from global south and north alike, the Council was duly queered and filled with intrigue.

This event was a landmark within the U.N. system, but it represents a particular win amidst a rollercoaster of to and fro in the political landscape of sexual rights, and specifically sexual orientation and gender identity ("SOGI," as we now call it), within the U.N. The backlash against any "progressive" or feminist focus on sexuality -- including claims for autonomous decision making about sex or reproduction, or sexuality education, or even freedom from discrimination -- is fierce and crosses continents with dizzying speed.

While the SOGI panel was breaking new ground in Geneva, at literally the same time at the U.N. in New York, the Holy See (which functions as a state within the U.N.), conservative governments, and a handful of U.S. right-wing organizations were boldly doing damage at the Commission on the Status of Women, the U.N.'s annual meeting on rights of women. Their goals were tried and true: In government negotiations, promote a monolithic heterosexual notion of "the" family; block promotion of comprehensive sexuality education; weaken any language that could support women's access to abortion or reproductive-health services, and stifle references to "key populations" affected by the AIDS pandemic -- specifically men who have sex with men, or sex workers.

In these spaces of global governance, the resistance to women's and LGBT rights is profound and often revealed in side programming alongside the official negotiations. Back in Geneva, two days after the pioneering SOGI panel, the Holy See hosted a hastily put-together, somewhat veiled anti-gay, unofficial event at the Human Rights Council. Abortion-related rights provide the Holy See's other rallying point, with support of conservative governments and many U.S. right-wing groups. Some of the unofficial U.N. events these groups host are (this can't be said diplomatically) mindblowing: some promote the value of breastfeeding but maintain a main plot that links abortion to breast cancer. For the record, the World Health Organization debunked this connection years ago. These events come across as desperate attempts to roll back the clock or, in this case, the legacy of progressive social movements, scientific evidence-based study, and even international human-rights law. And they're painful to sit through, too.

OK, so that was March in the UN. Bring on April and the U.N. Commission on Population and Development (CPD), another annual, week-long, governmental meeting in New York attended by many sexual- and reproductive-rights and right-wing organizations. Fasten your seatbelts: Here's another swervy ride.

The CPD always has a theme related to health; this year's was "adolescents and youth." Remarkably, the CPD produced a resolution calling on governments to protect human rights of adolescents and youth "to have control over and decide freely and responsibly on matters related to their sexuality, including sexual and reproductive health," and to provide them with "evidence-based comprehensive education on human sexuality." These are big wins that fly in the face of conservative efforts to regulate sexuality of young people. But these gains came with compromises. Gender- and sexual-rights language became lightning rods, because they were seen as "covers" for sexual orientation and gender identity.

So even as an official human-rights panel on sexual orientation and gender identity takes place in one U.N. site, the ideas supporting that work become lynchpins in another U.N. venue 3,000 miles away. And even when allies try to focus on the daily violence and discrimination LGBT people face in all regions, what's heard by those in opposition is entirely different: They hear (because they want to) "demise of marriage," "the ruin of the family," and "the end of child bearing."

There was a not-very-interesting walkout by some governments as the official panel on sexual orientation and gender identity began at the Council. In fact, some of the same delegates who left the room were spotted in the overflow viewing gallery minutes later. Activism lesson: If you're going to stage a walkout, at least leave the building. Their opposition generally rested on weak and manipulated arguments about international law: "Homosexuality is a 'Western import,' is not mentioned in the Universal Declaration of Human Rights, and has no place being discussed in a context of international law," or, "This discussion is about affording 'special rights' to a specific group."

These arguments are, of course, paper-thin. The human-rights framework argues that all people should be able to enjoy all human rights, and that no one should be subjected to violence (including torture, extrajudicial killing, or violence in the home) or discrimination (including arbitrary arrest, or denial of education or health care).

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Cynthia Rothschild: Oh, the Drama! The UN Human-Rights System Tackles Sexual Orientation and Gender Identity

People's Geographic Origins Traceable With New Genetic Method

Featured Article Academic Journal Main Category: Genetics Also Included In: IT / Internet / E-mail;Medical Devices / Diagnostics Article Date: 29 May 2012 - 11:00 PDT

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The team, from the University of California - Los Angeles (UCLA) Henry Samueli School of Engineering and Applied Science, UCLA's Department of Ecology and Evolutionary Biology, and Tel Aviv University, write about their work in a paper published online in Nature Genetics on 20 May.

The researchers hope their method, which they call "spatial ancestry analysis" or SPA, will increase understanding of genetic diversity among populations, which in turn helps us better understand human disease and evolution.

Research areas that may benefit from the new method include finding links between genetic variants and disease and locating parts of genomes that have been subject to positive selection.

SPA is a software tool for analyzing spatial structure in genetic data. It models genotypes in two- and three-dimensional space.

With SPA researchers can model the spatial distributon of each genetic variant. And in this study, the team showed that particular frequency patterns of spatial distribution of gene variants are tied to particular geographic locations.

For genetic variants the team used SNPs ("snips", short for single-nucleotide polymorphisms) from various parts of the genome, including "the well-characterized LCT region, as well as at loci including FOXP2, OCA2 and LRP1B".

An SNP is a DNA sequence variation where there is a single nucleotide (A, T, C or G) difference in the "spelling" of the sequence.

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People's Geographic Origins Traceable With New Genetic Method

Chronic Inflammation Gene May Destroy Tumors

Editor's Choice Main Category: Cancer / Oncology Also Included In: Genetics Article Date: 28 May 2012 - 16:00 PDT

Current ratings for: 'Chronic Inflammation Gene May Destroy Tumors'

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Robert J. Schneider, PhD, the Albert Sabin Professor of Molecular Pathogenesis and associate director for translational research and co-director of the Breast Cancer Program at the NYU Langone Medical Center, who was the principal investigator of the study, declared:

Scientists have known for decades that accelerated ageing, inflammation and cancer are somehow related, yet exactly how these conditions are linked has so far been unknown. The little knowledge available has partly been obtained in Schneider's previous studies, mainly that a gene called AUF1 controls inflammation by switching off the inflammatory response to prevent the onset of septic shock, and although this finding is significant, it fails to shed light on the link to ageing and cancer. The team observed that accelerated ageing occurred when the AUF1 gene was deleted, which led them to investigate further. A decade later, they have finally discovered the link between inflammation, advanced aging and cancer.

They found out that aside from controlling inflammation, AUF1, which belongs to a family of four related genes, also maintains the integrity of chromosomes. It activates telomerase, an enzyme, to repair the ends of chromosomes, and by doing so, it simultaneously reduces inflammation, prevents rapid aging and cancer from developing. Dr. Schneider explained: "AUF1 is a medical and scientific trinity. Nature has designed a way to simultaneously turn off harmful inflammation and repair our chromosomes, thereby suppressing aging at the cellular level and in the whole animal."

Armed with this new discovery, Dr. Schneider and his team are currently researching how the alterations manifest and present themselves clinically. They are examining human populations for specific types of genetic changes in the AUF1 gene, which are associated with rapid ageing, higher risk of cancer and co-developments of certain immune diseases.

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WAYNE COUNTY: Wayne State chemistry department among top 100 worldwide

Wayne State University's Department of Chemistry is among the top 100 in the world, according to the latest ranking by the Academic Ranking of World Universities (ARWU). More than 1,000 universities were ranked in 2011, and the best 500 are published at http://www.shanghairanking.com/.

The ARWU uses six indicators to determine rankings. WSU received high marks in three: highly cited researchers, papers in the Science Citation Index, and percentage of papers published in the top 20 percent of journals.

"The chemistry department is excited to learn that we have been ranked among the elite chemistry departments in the world.Our inclusion among the best in the world is a welcome recognition of our efforts over the last several years to make Wayne State chemistrytruly first-rate in both teaching and research.With the recent opening of the newly renovated A. Paul Schaap Chemistry Building, we are well-positioned to move to the next level of excellence," said Jim Rigby, chemistry department chair.

The only other Michigan university receiving top 100 honors in chemistry was the University of Michigan-Ann Arbor.

The ARWU uses six indicators to determine rankings. WSU received high marks in three: highly cited researchers, papers in the Science Citation Index, and percentage of papers published in the top 20 percent of journals.

"The chemistry department is excited to learn that we have been ranked among the elite chemistry departments in the world.Our inclusion among the best in the world is a welcome recognition of our efforts over the last several years to make Wayne State chemistrytruly first-rate in both teaching and research.With the recent opening of the newly renovated A. Paul Schaap Chemistry Building, we are well-positioned to move to the next level of excellence," said Jim Rigby, chemistry department chair.

The only other Michigan university receiving top 100 honors in chemistry was the University of Michigan-Ann Arbor.

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DGAP-News: Cytos Biotechnology Ltd Nominates Dr. Christian Itin, former President and CEO of Micromet Inc., as a Non …

Cytos Biotechnology Ltd Nominates Dr. Christian Itin, former President and CEO of Micromet Inc., as a Non-executive Director

Schlieren (Zurich), Switzerland, May 29, 2012 - Cytos Biotechnology Ltd (Cytos or the Company), a Swiss biotech company developing a new class of biopharmaceutical products called Immunodrugs(TM), announced today the nomination of Dr. Christian Itin to its Board as a Non-executive Director and that the Board of Directors will propose to the Companys shareholders the election of Dr. Itin as member of the Board at the Companys next general meeting.

Dr. Itin (age 48 yrs) is the former President and Chief Executive Officer of Micromet Inc., a formerly Nasdaq-listed biopharmaceutical company, with headquarters in Rockville, MD and a R&D center in Munich, Germany, which was acquired in March 2012 by Amgen, Inc. for USD 1.16 billion in cash. He spent 13 years with Micromet in a number of senior management roles, becoming CEO in 2004. Prior to joining Micromet in 1999, Dr. Itin co-founded Zyomyx, Inc., a protein chip company based in Hayward, CA, USA.

Dr. Itin received a diploma in biology and a Ph.D. in cell biology from the University of Basel. In addition, he performed post-doctoral research at the Biocenter of Basel University and at the Stanford University School of Medicine.

Thomas Hecht, Chairman of Cytos, said: Christian is an experienced biotech entrepreneur with significant expertise and a strong track record in areas such as R&D strategy, corporate, business and product development. These attributes are extremely important to Cytos as Cytos is looking to build significant value from its Immunodrug(TM) platform following its recent CHF 33.5 million (USD 36.2 million) financing round. We are looking forward to Christians contributions to Cytos growth and future success.

Christian Itin, commented: Over recent months, Cytos has established a strong foundation on which to build an exciting company based on CYT003, a novel potentially disease-modifying approach to asthma and also on its unique Immunodrug(TM) platform. I believe the Company has a promising future and I am very pleased to have the opportunity to support its growth and development.

For further information please contact:

Cytos Biotechnology Ltd Harry Welten Chief Financial Officer Tel.: +41 44 733 46 46 e-Mail: harry.welten@cytos.com Website: http://www.cytos.com

About Cytos Biotechnology Ltd Cytos Biotechnology Ltd is a Swiss public biotechnology company that specializes in the development and commercialization of a new class of biopharmaceutical products - the Immunodrugs(TM). Immunodrugs(TM) are intended for use in the treatment and prevention of common chronic diseases, which afflict millions of people worldwide. Immunodrugs(TM) are designed to instruct the patients immune system to produce the desired therapeutic antibody or T cell responses that modulate chronic disease processes. Cytos Immunodrug(TM) candidates are being developed both in-house and together with Novartis, Pfizer and Pfizer Animal Health. Founded in 1995 as a spinoff from the Swiss Federal Institute of Technology (ETH) in Zurich, the Company is located in Schlieren (Zurich). Cytos Biotechnology Ltd is listed according to the Main Standard on the SIX Swiss Exchange Ltd under the symbol CYTN.

This foregoing press release may contain forward-looking statements that include words or phrases such as are intended for, are designed to, or other similar expressions. These forward-looking statements are subject to a variety of significant uncertainties, including scientific, business, economic and financial factors, and therefore actual results may differ significantly from those presented. There can be no assurance that any further therapeutic entities will enter clinical trials, that clinical trial results will be predictive for future results, that therapeutic entities will be the subject of filings for regulatory approval, that any drug candidates will receive marketing approval from the U.S. Food and Drug Administration or equivalent regulatory authorities, or that drugs will be marketed successfully. Against the background of these uncertainties readers should not rely on forward-looking statements. The Company assumes no responsibility to update forward-looking statements or adapt them to future events or developments.

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DGAP-News: Cytos Biotechnology Ltd Nominates Dr. Christian Itin, former President and CEO of Micromet Inc., as a Non ...

Beike Earns AABB Accreditation for Cord Blood and Cord Tissue Banking

SHENZHEN, China, May 29, 2012 /PRNewswire-Asia/ --Beike Biotechnology Co., Ltd ("Beike") announced that it has been awarded AABB accreditation for cord blood and cord tissue banking. This accreditation has been granted following an intensive on-site assessment by AABB assessors and establishes that the level of medical, technical and administrative performance within the facility is in accordance with the AABB standards or exceeds those set by AABB. With this achievement, Beike becomes China's first and only AABB-accredited stem cell bank for both cord blood and cord tissue banking.

Ying Song, MD, PhD, Medical Director of Beike, stated, "It is a proud moment for us that Beike is the first and the only stem cell bank in China to possess AABB accreditation for both cord blood and cord tissue and this reflects our commitment to quality. It is also noteworthy to mention that Beike is among the first stem cell banks in the world to receive AABB accreditation for cord tissue banking which positions Beike as a leader in stem cell preservation."

Beike began the comprehensive AABB accreditation process in March 2010 and completed the on-site assessment in September 2011. The accreditation assessment included stem cell processing, records, document control, inspection and testing, technician training, sample identification, traceability and validations. During this audit, it was determined that Beike's medical, technical and administrative performance met the standards set by the AABB. Beike was issued its AABB certificate in January 2012.

Dr. Shengqin Ye, President of Beike, commented, "We are extremely pleased to have been granted this accreditation. With this, Beike has once again demonstrated a commitment to advanced learning, continuous improvement and innovation to sustain the highest possible level of quality and safety."

To meet AABB standards, Beike adopted new technology for stem cell processing (AXP AutoXpress system), storage (BioArchive Systems), and testing (Beckman hematology analyzer LH750 and Tecan Freedom EVOlyzer). Additionally, the company optimized its information technology platform and software systems, adding an advanced bar code management system, real-time monitoring capabilities, and an advanced enterprise resource planning (ERP) system to its call center.

About Beike Biotechnology Company:

Shenzhen Beike Biotechnology Co., Ltd. is China's leading biotechnology company focusing on banking adult stem cells and developing new cell based medicinal products. Headquartered in Shenzhen (near Hong Kong) with a flagship regenerative medicine facility at the China Medical City in Jiangsu province, Beike produces a full line of stem cell products derived from umbilical cord, cord blood and autologous bone marrow.

About AABB:

AABB (formerly the American Association of Blood Banks) is an international non-profit body dedicated to developing the highest standards in blood and cord blood banking, transfusion medicine and cellular therapy. The association is committed to improving health by developing and delivering standards, accreditation and educational programs that focus on optimizing patient and donor care and safety.

Based in the United States, AABB represents more than 2,000 institutions and 8,000 individuals in 80 countries, involved in collecting, processing, testing, distributing, or transfusing blood, blood components, or cellular therapy products.

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Beike Earns AABB Accreditation for Cord Blood and Cord Tissue Banking

Anatomy of a double bagel: Maria Sharapova wins 6-0, 6-0

(Getty Images)

Maria Sharapova took the court Tuesday at 11 a.m. in Paris to begin her 2012 French Open against Alexandra Cadantu. She walked off 48 minutes later, dropping a double bagel on the young Romanian. It was the fourth such scoreline of Sharapova's career. Interestingly, the previous three had all come against American players, including that famous 2005 drubbing of world No. 1 Lindsay Davenport at Indian Wells.

What does the stats from a 6-0, 6-0 match look like? Not that much different than a 6-2, 6-2 match, to be honest.

(Roland Garros 2012)

Those are the first four stats listed on the official Roland Garros site and they provide no indication of the drubbing that took place. It takes a little longer to get to those numbers.

(Roland Garros 2012)

What's most amazing about those numbers aren't Cadantu's zero winners. It's that she actually had three break-point chances against the dominant Sharapova.

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Anatomy of a double bagel: Maria Sharapova wins 6-0, 6-0

Study of the Day: A Diet Loaded With Sugar Makes Rats Dumber

New research in the Journal of Physiology suggests that fructose disrupts learning and memory, but omega-3 fatty acids can help.

PROBLEM: The average American consumes roughly 47 pounds of cane sugar and 35 pounds of high-fructose corn syrup per year, mostly through processed foods like soft drinks, condiments, and desserts. Though previous studies have shown how these sweeteners harm the body through its role in diabetes, obesity, and fatty liver, it was unclear if they had impact on mental processes.

METHODOLOGY: University of California, Los Angeles, researchers Rahul Agrawal and Fernando Gomez-Pinilla trained two groups of rats on a maze twice daily for five days before serving them a fructose solution as drinking water for six weeks. The second group also received omega-3 fatty acids, which protect against damage to the synapses or the chemical connections between brain cells that enable memory and learning. After this experimental diet period, the researchers tested the rats' ability to recall the visual landmarks the scientists installed to help them escape the maze.

RESULTS: The second group of rats remembered the correct route and were able to exit much faster than the rats that did not receive omega-3 fatty acids in the form of docosahexaenoic acid (DHA) and flaxseed oil. A closer look at the brains of the DHA-deprived mammals showed a decline in synaptic activity and signs of resistance to insulin, a hormone that controls blood sugar and regulates synaptic function.

CONCLUSION: A high-fructose diet sabotages learning and memory, but omega-3 fatty acids can partially offset the damage.

IMPLICATION: Gomez-Pinilla says consuming one gram of DHA per day through foods rich in omega-3 fatty acids like salmon, walnuts, and flaxseeds can protect the brain against fructose's dumbing effects. "It's like saving money in the bank," he says in a statement. "You want to build a reserve for your brain to tap when it requires extra fuel to fight off future diseases."

SOURCE: The full study, "Metabolic Syndrome' in the Brain: Deficiency in Omega-3 Fatty Acid Exacerbates Dysfunctions in Insulin Receptor Signalling and Cognition," is published in the Journal of Physiology.

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Study of the Day: A Diet Loaded With Sugar Makes Rats Dumber

Nutrition program offers breakfast, lunch to kids

WEATHERFORD Weatherford ISD is making it easier on parents this summer, by offering their annual Summer Meals program, beginning June 4.

Funded through a grant and paid for by the state, the program offers free breakfast and lunch to kids and youth up to the age of 18.

Some kids may not get the nutritional meals they need in the summer, especially if the parents are at work, Jerolyn Goodman, a registered dietitian and director of the WISD child nutrition services, said. The neat thing is that they dont even have to be Weatherford students or live in town. Anyone up to 18 can come and eat for free.

The program will be held at Ikard Elementary, 100 Ikard Lane, and runs through Aug. 10. Services will not be available July 4.

Breakfast will be served Monday through Friday, from 8 to 9 a.m., and lunch from 11 a.m. to 12:30 p.m.

For the longest time, we were the only place in Parker County that offered it, but there really hasnt been a big turnout, Goodman said. We really want people to come out.

Breakfast is available for accompanying adults for $2, and lunch for $3.25.

Its a good way, if youre out and about, to just stop by and feed your kids a nutritious lunch for free, Goodman said.

With a variety of meals, Goodman said that pizza and hot dogs are the top favorites, noting that kids can count on pizza every Thursday.

In addition to the meals, Kids Unite programs will also be going on, with anyone welcome to attend.

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Nutrition program offers breakfast, lunch to kids

Foods, nutrition professor named to UGA Foundation Professorship

Richard D. Lewis, professor of foods and nutrition in the University College of Family and Consumer Sciences, has been named to the UGA Foundation Professorship in Family and Consumer Sciences.

Since joining the College of Family and Consumer Sciences in 1986, Dr. Lewis has excelled in teaching, research and outreach, said FACS Dean Linda K. Fox. His research on topics related to bone strength have been on the cutting edge, and he has incorporated the newest research findings into the courses he regularly teaches on life-cycle nutrition and medical nutrition therapyas well as seeking opportunities for students to engage in service-learning projects.

Richard D. Lewis, professor of foods and nutrition was named to the UGA Foundation Professorship in Family and Consumer Sciences.

Lewis spent his first five years at UGA as a nutrition and health specialist with UGA Cooperative Extension, working specifically on programs related to weight control for adults and healthy lifestyles for children. In 1992, his focus shifted to teaching and research, and he began exploring the impact of gymnastics on female bone strength.

Soon after I joined the university, I began providing nutritional guidance to our athletes on a volunteer basis, Lewis said. When we decided to explore this research question (of gymnastics and bone strength), it was generally thought that the excessive exercise and food restriction that is often found in gymnastics would have a negative impact on bone strength. On the contrary, our research showed that college gymnasts had very dense bones.

Lewiss research was one of only two projects on the topic published nationally in 1995, putting him at the forefront of the field. Among the unique aspects of the study was the use of non-gymnast controls.

We made sure that every gymnast was matched with regard to their age, height, weight and other factors to ensure that we could relate the difference in bone strength to gymnastics rather than other factors, he said.

Lewis has gone on to measure bone strength in retired competitive gymnasts at the ages of 35 and 45. He is now beginning to look at 55-year-old former gymnasts to gauge whether higher bone strength continues into their menopausal years. He also has looked at children as young as four to determine when bone strength differences begin.

His other research includes pioneering a federally funded study into the role of vitamin D in developing bone strength in children, a topic he will lecture on at a conference in Switzerland, and examining the use of soy isoflavones to counteract menopause-related bone loss in women.

His current research focuses on the role a common virus may play in bone strength among obese children. He also is working with colleagues on additional projects related to UGAs obesity initiative.

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Foods, nutrition professor named to UGA Foundation Professorship

Updated Academy of Nutrition and Dietetics Position Paper Confirms Safety and Benefits of Low-Calorie Sweeteners

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Updated Academy of Nutrition and Dietetics Position Paper Confirms Safety and Benefits of Low-Calorie Sweeteners