Chemistry professor remembered for dedication

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Benjamin Burtt will be remembered by his colleagues and students as a pleasant, organized professor with a passion for teaching and a great influence over those he taught.

The former Syracuse University professor emeritus died at age 91 on Feb. 23 in Columbus, Ohio. He taught chemistry at SU for 47 years.

"He was so professional. He was so sure of himself. He knew what he was going to do, and he developed that in his students' minds," said Sally Mitchell, a 1982 SU alumna. "He really loved what he did."

Mitchell, now a chemistry teacher at East Syracuse-Minoa High School, keeps a photo of Burtt from the 1940s in her classroom, and Burtt's son gave her Burtt's original "magic" chemistry demonstration book. She said she models her teaching style after the late professor.

Burtt was well known for his lecture on water in his freshman chemistry class toward the end of each semester. In that lecture, Burtt would perform various experiments that were both entertaining and informative.

"Everything he did was funny, and he kept a straight face the whole time," said Mitchell. "It was the most entertaining chemistry demo show that I've ever seen."

The water lecture will be recreated and performed June 21 in Stolkin Auditorium, Mitchell said, as a public event in honor of Burtt. She will be using flasks, test tubes and beakers that Burtt handed down to her during the experiments.

Mitchell attended Burtt's water lecture each year during her time at school, and she credits it as her inspiration to become a chemistry teacher. She said Burtt's son, Academy Award-winning sound designer Benjamin Burtt Jr., has put together tapes of the lecture on DVD to preserve it.

Aside from his love for teaching chemistry, Burtt is remembered for another passion: bird watching.

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Chemistry professor remembered for dedication

Angel Biotechnology – Appointment of acting CEO

05 March 2012

Angel Biotechnology Holdings plc

("Angel" or "the Company")

Appointment of Dr. Stewart White as Acting CEO

Angel Biotechnology Holdings plc, (AIM:ABH), the biopharmaceutical contract manufacturer, is about to enter what the Directors believe is an unprecedented period of growth. The Cramlington facilty will shortly come on line for non-GMP (KOSDAQ: 018290.KQ - news) activities and we are working on a number of other projects. This means that we must re-structure our staff around the needs of the business and we expect to make a number of new appointments to augment our existing senior team.

As part of this re-structuring activity the Board is pleased to announce the appointment of Dr. Stewart White as Acting CEO following the decision of the COO, Mr. Gordon Sherriff to leave the Company. Dr. White was recruited into his present position as Commercial Director with a view to his progression to becoming CEO in due course. Stewart has made a significant impact on the business since joining Angel in December 2011 and the Board has every confidence in Stewart's ability to fulfill this new role and for the appointment to be made permanent after a period of evaluation.

Dr. Paul Harper, Executive Chairman, said: "Stewart has made an excellent start in his role at Angel, bringing drive, focus and leadership in his current role and more broadly across the business. During Gordon Sherriff's period of absence, Stewart has assumed a broad range of responsibilities alongside Lorna Peers, our FD, and myself. The senior staff have responded magnificently to the new challenges and greater responsibility supported by a steady stream of new appointments at both Pentlands and Cramlington."

For further information:

Angel Biotechnology Holdings plc

Lorna Peers, Finance Director +44 (0) 131 445 6077

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Angel Biotechnology - Appointment of acting CEO

Plandai Biotechnology, Inc. Discusses Impact of Recent Study on Benefits of Green Tea Gallate Extract in Treating …

SEATTLE, WA--(Marketwire -03/05/12)- Planda Biotechnology, Inc. (OTC.BB: PLPL.OB - News) Chief Executive Officer Roger Duffield today discussed a recently published study that demonstrated improved function in the area of the pancreas responsible for insulin production in laboratory mice treated with chemicals found in green tea gallate extract.

The study, published in Nutrition & Metabolism, reported the results of diabetes susceptible mice that had received a clinical dose of EGCG (epigallocatechin gallate), one of the four primary catechins found in fresh tea leaves. The EGCG supplementation appeared to not only protect the islets of Langerhans in treated mice from the changes associated with onset diabetes, but were shown to have increased the number and size of the islets. Beta cells found in the islets of Langerhans, located in the pancreas, are responsible for insulin production in humans. The study concluded that dietary supplementation of purified ECGC could be a way to confer beta cell protection and encouraged randomized, placebo-controlled trials.

Mr. Duffield commented, "The anecdotal benefits of green tea have been known for centuries, with herbalists using it to benefit cardiovascular health and help treat certain cancers among a long list of other perceived benefits. It's exciting to now see medical science coming on board and supporting what we've always known. Planda's proprietary process for producing green tea gallate catechin extract in a manner that is more cost effective and with improved bioavailability sets us in the forefront of this rapidly expanding market."

According to the World Health Organization, diabetes affects more than 220 million people globally and the consequences of high blood sugar kills 3.4 million every year. The total costs associated with treating this condition are estimated at $174 billion annually, with $116 billion being direct costs for medication.

The full study is titled "Diet Supplementation With Green Tea Extract Epigallocatechin Gallate Prevents Progression To Glucose Intolerance In db/db Mice," was published February 14, 2012 in Nutrition & Metabolism, and is available at http://www.nutritionandmetabolism.com.

About Planda Biotechnology, Inc.

Planda Biotechnology, Inc., through its recent acquisition of Global Energy Solutions, Ltd. and its subsidiaries, focuses on the farming of whole fruits, vegetables and live plant material and the production of proprietary functional foods and botanical extracts for the health and wellness industry. Its principle holdings consist of land, farms and infrastructure in South Africa.

Safe Harbor Statement

The information provided may contain forward-looking statements and involve risks and uncertainties. Results, events and performances could vary from those contemplated. These statements involve risks and uncertainties which may cause actual results, expressed or implied, to differ from predicted outcomes. Risks and uncertainties include product demand, market competition, and Planda's ability to meet current or future plans. Investors should study and understand all risks before making an investment decision. Readers are recommended not to place undue reliance on forward-looking statements or information. Planda is not obliged to publicly release revisions to any forward-looking statement, to reflect events or circumstances afterward, or to disclose unanticipated occurrences, except as required under applicable laws.

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Plandai Biotechnology, Inc. Discusses Impact of Recent Study on Benefits of Green Tea Gallate Extract in Treating ...

Plandai Biotechnology, Inc. Discusses Advantages of Its Green Tea Extract Over Competing Technology

SEATTLE, WA--(Marketwire -03/05/12)- Planda Biotechnology, Inc. (OTC.BB: PLPL.OB - News) Chief Executive Officer Roger Duffield today addressed the science behind the company's green tea gallate catechin extract, explaining why Planda has a competitive advantage over other bioceutical extracts.

Medical research has long acknowledged the benefits of a diet rich in antioxidants for aiding in cardiovascular health and boosting the immune system. Antioxidants occur naturally within the human body, with the supplement market existing to increase antioxidant levels to their optimum. Antioxidants include Vitamin C found in fresh fruits and vegetables, carotenoids (including lycopene) also found in fruits and vegetable with a high concentration in tomatoes, and flavonoids which are found in tea, red wine, chocolate and cinnamon.

In human tissue, antioxidants are normally found in both cis and trans isomer compounds in a 50/50 ratio. The fruits, vegetables and other antioxidants we consume, however, typically have a 95/5 ratio. Even the extracts sold as supplements maintain this ratio. Synthetic supplements, which may be formulated to the ideal 50/50 ratio are often difficult for the body to absorb and may cause side effects.

Planda's Phytofare Green Tea Gallate Catechin Extract is processed to deliver a highly bioavailable, antioxidant-rich material to a level many times that of other green tea extracts through the creation of the desired ratio of cis/trans isomers. Mr. Duffield added, "Research has shown that green tea gallate catechins are extremely active antioxidants and in a bioavailable form, are able to protect the red and white blood cells against attack. Planda's Phytofare Green Tea Gallate Catechin Extract offers disease prevention and does not provide a cure. For patients suffering from a compromised immune system, including those undergoing chemotherapy or suffering from Malaria, HIV-1 and other immunosuppressant diseases, we believe our extract offers meaningful protection to the individuals compromised immune system."

About Planda Biotechnology, Inc.

Planda Biotechnology, Inc., through its recent acquisition of Global Energy Solutions, Ltd. and its subsidiaries, focuses on the farming of whole fruits, vegetables and live plant material and the production of proprietary functional foods and botanical extracts for the health and wellness industry. Its principle holdings consist of land, farms and infrastructure in South Africa.

Safe Harbor Statement

The information provided may contain forward-looking statements and involve risks and uncertainties. Results, events and performances could vary from those contemplated. These statements involve risks and uncertainties which may cause actual results, expressed or implied, to differ from predicted outcomes. Risks and uncertainties include product demand, market competition, and Planda's ability to meet current or future plans. Investors should study and understand all risks before making an investment decision. Readers are recommended not to place undue reliance on forward-looking statements or information. Planda is not obliged to publicly release revisions to any forward-looking statement, to reflect events or circumstances afterward, or to disclose unanticipated occurrences, except as required under applicable laws.

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Plandai Biotechnology, Inc. Discusses Advantages of Its Green Tea Extract Over Competing Technology

Smart, self-healing hydrogels open far-reaching possibilities in medicine, engineering

Public release date: 5-Mar-2012 [ | E-mail | Share ]

Contact: Catherine Hockmuth chockmuth@ucsd.edu 858-822-1359 University of California - San Diego

University of California, San Diego bioengineers have developed a self-healing hydrogel that binds in seconds, as easily as Velcro, and forms a bond strong enough to withstand repeated stretching. The material has numerous potential applications, including medical sutures, targeted drug delivery, industrial sealants and self-healing plastics, a team of UC San Diego Jacobs School of Engineering researchers reported March 5 in the online Early Edition of the Proceedings of the National Academy of Sciences.

Hydrogels are made of linked chains of polymer molecules that form a flexible, jello-like material similar to soft-tissues. Until now, researchers have been unable to develop hydrogels that can rapidly repair themselves when a cut was introduced, limiting their potential applications. The team, led by Shyni Varghese, overcame this challenge with the use of "dangling side chain" molecules that extend like fingers on a hand from the primary structure of the hydrogel network and enable them to grasp one another.

"Self-healing is one of the most fundamental properties of living tissues that allows them to sustain repeated damage," says Varghese. "Being bioengineers, one question that repeatedly appeared before us was if one could mimic self-healing in synthetic, tissue-like materials such as hydrogels. The benefits of creating such an aqueous self-healing material would be far-reaching in medicine and engineering."

To design the side chain molecules of the hydrogel that would enable rapid self-healing, Varghese and her collaborators performed computer simulations of the hydrogel network. The simulations revealed that the ability of the hydrogel to self-heal depended critically on the length of the side chain molecules, or fingers, and that hydrogels having an optimal length of side chain molecules exhibited the strongest self-healing. When two cylindrical pieces of gels featuring these optimized fingers were placed together in an acidic solution, they stuck together instantly. Varghese's lab further found that by simply adjusting the solution's pH levels up or down, the pieces weld (low pH) and separate (high pH) very easily. The process was successfully repeated numerous times without any reduction in the weld strength.

Ameya Phadke, a fourth year PhD student in Varghese's lab said the hydrogel's strength and flexibility in an acidic environment similar to that of the stomach makes it ideal as an adhesive to heal stomach perforations or for controlled drug delivery to ulcers.

Such healing material could also be useful in the field of energy conservation and recycling where self-healing materials could help reduce industrial and consumer waste, according to Varghese. Additionally, the rapidity of self-healing in response to acids makes the material a promising candidate to seal leakages from containers containing corrosive acids. To test this theory, her lab cut a hole in the bottom of a plastic container, "healed" it by sealing the hole with the hydrogel and demonstrated that it prevented any leakage of acid through the hole.

Moving forward, Varghese and her lab hope to test the material in its envisioned applications on a larger scale. The team also hopes to engineer other varieties of hydrogels that self-heal at different pH values, thereby extending the applications of such hydrogels beyond acidic conditions.

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Smart, self-healing hydrogels open far-reaching possibilities in medicine, engineering

Penn Biochemist Receives Hodgkin Award from The Protein Society

PHILADELPHIA Mark A. Lemmon, PhD, chair of the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania, is the 2012 recipient of the Dorothy Crowfoot Hodgkin Award by The Protein Society. The award will be presented at the 26th Annual Symposium of The Protein Society in August, during the Plenary Awards Session.

The Dorothy Crowfoot Hodgkin Award, is given in recognition of exceptional contributions in protein science, which profoundly influence our understanding of biology. Dr. Lemmon is being recognized for major contributions to the field of signal transduction and transmembrane signaling mechanisms of receptor tyrosine kinases. Crystallographic, biochemical, and genetic studies from his laboratory have provided sophisticated understanding of EGFR cell signaling. His discoveries of the mechanisms for the epidermal growth factor receptor family offer new ideas for developing therapies targeting cancer and other human diseases.

"Of course, it's not really my work that this award honors, but really that of several fantastic Penn postdocs and students," says Lemmon. "First, I'd particularly like to single out Diego Alvarado, Daryl Klein, Sung Hee Choi, Jeannine Mendrola and Fumin Shi for the EGF receptor work that the award cites. They are all great examples of the superb scientists that Penn Medicine attracts and reasons why it's so great to be here.

"Second, Dorothy Crowfoot Hodgkin has always been a hero of mine. She did much of her secondary education in the part of England where I grew up and was already a legend at Oxford when I went there. Her crystallographic studies of insulin -- well after her 1964 Nobel Prize -- inspired much of our structural work in EGF signaling. I always found it interesting too given her politics - that Margaret Thatcher was one of Professor Hodgkin's most famous students."

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Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $4 billion enterprise.

Penn's Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools and among the top 10 schools for primary care. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $507.6 million awarded in the 2010 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top 10 hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2010, Penn Medicine provided $788 million to benefit our community.

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Penn Biochemist Receives Hodgkin Award from The Protein Society

Anatomy of a Government Phone, or, Can the NSA Build an Android?

The craziest thing about a typical "top secret" U.S. Government phone is that you can probably spot it from a football field away. If your mental picture of a Hollywood-style NSA agent drives a black AMC Ambassador, wears a polyester suit and Ray-Bans, and smokes Luckies, then his phone may either be Maxwell Smart's shoe or a General Dynamics Sectera Edge (pictured left). At any distance, it looks like one of the pocket football games my junior high school vice principal used to confiscate and collect in his back drawer.

The National Security Agency wants a real-world smartphone, not the one it has now - not the one you see here. Of course, it must fulfill the Dept. of Defense's requirements for session encryption and data retention. But beyond that fact, the NSA wonders why its secure phone can't have multitouch, apps, and speed just like the civilians have. Based on looks alone, you'd think the civilians are a couple of pegs ahead of the G-men. This is a story of looks being more deceptive than even a security agency could have anticipated.

The real face of the National Security Agency looks more like Margaret Salter. At the RSA Conference in San Francisco last Wednesday, Salter told attendees the story of the NSA's Secure Mobility Strategy. She leads a department called the Information Assurance Directorate. For the better part of four decades, IAD has been tasked with securing secret government communications, and building specifications for the tools to do it. The NSA contracts with private suppliers to build a class of devices it calls GOTS (government off-the-shelf). The gestation cycle for each of these devices - from the conceptual stage, to development, to deployment - typically consumes years. Perhaps the best-known GOTS product is still in wide use today - 1987's STU-III secure telephone, which looks about as home on an agent's desk today as an IBM PC.

Still, as Salter told the RSA attendees, for the better part of half a century, the NSA explicitly defined its own market, a private universe of products made for its own exclusive consumption. "That was cool for us, for the longest time. We kinda had a monopoly on this from the very beginning," she remarked. "We were mostly building things like radios for combat, [and] big link encryptors to hook one site up to another site."

But their ease of use ranked right up there with a World War II cipher machine. "Once you get something in the hands of an individual user who's not a cleared COMSEC custodian, someone who knows what they're supposed to be doing with this stuff and understands all the details, ease of use became incredibly freakin' important. And it turned out that, although our stuff was incredibly secure, it was not incredibly easy to use."

Over time, it became more difficult over time for the agency to define "ease of use" on a comparative scale. In just the last five years, the consumer universe appeared to leave the NSA's secure market behind. "The world everyone wants is, I want to get what I want, when I want it, where I want it."

Salter's team considered whether it was feasible for NSA to utilize a real, commercial smartphone - one like all the kids are using nowadays - but with software that made the device perhaps more secure than the Sectera Edge. "The phones are so popular and exploding all over the place, because we can play Angry Birds on them, and do whatever you want. But we needed enterprise management - some control over it, because honestly, we didn't really want you to be able to go load Angry Birds on your TS [top secret] phone... That was not a business model that we could support, or even defend."

They launched Project Fishbowl, a pilot to produce a smartphone made of mostly commercial parts and infrastructure (more COTS than GOTS), capable of supporting classified voice and data, while remaining as easy to use as its civilian counterpart and staying inexpensive. The historical significance of the NSA embracing commercial crypto standards cannot be stressed enough. Anyone familiar with how RSA came to be in the first place will recall the fights its engineers faced keeping the government from classifying it, taking its power out of the public's hands. Perhaps the whole point of the RSA standard and the RSA conference is to promote the power of security for everyone through manageable encryption.

"So one of the things I harp on most is, why was that so hard?" remarked Salter.

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Anatomy of a Government Phone, or, Can the NSA Build an Android?

'Grey's Anatomy': Patrick Dempsey And Ellen Pompeo's Future In Question

"Grey's Anatomy" stars Patrick Dempsey and Ellen Pompeo's contracts are up at the end of Season 8. Though the two have spoken out about returning, series creator Shonda Rhimes said their future with the show is still in question. "I have my fingers crossed," Rhimes told TV Guide when asked if the two were returning. "What I think is really lovely is that everybody wants to come back."

After making some seemingly final comments regarding his future with the show, Dempsey hedged and said he'd be open to discussing signing a new contract.

"I have a family to support, and why not have a discussion about continuing?" he said. "The question is will I do a full season, a half season or come back at all?"

Meanwhile, Pompeo said she'd "never turn up my nose at 'Grey's.'"

"If I hear from the fans that they want us to keep going, then I would continue because we owe them everything," Pompeo told TV Guide in October.

Rhimes said she has a plan in place for the finale that will work regardless of who signs on for Season 9. "Our goal is to have Derek and Meredith move in to the completed dream house," she told TV Guide. "And our residents will be interviewing for jobs all around the country."

Pomepo and Dempsey aren't the only "Grey's" actors making headlines about their future with the show. While promoting her movie, former series star Katherine Heigl told multiple members of the press that she wants to return to "Grey's Anatomy" to check in on her character, Dr. Izzie Stevens.

"I just want to know what happened to her and where she went and what she's doing now," Heigl told E! Online. The "One For the Money" actress said she's even reached out to the show. "I've told them I want to," she said.

However, Pompeo told Chelsea Handler that having Heigl return to the ABC medical drama was unlikely. "I don't think that's happening," Pompeo said during an appearance on "Chelsea Lately."

As for Rhimes, the creator said it was nice to hear Heigl show some appreciation for the show, but "Grey's" is on a long-planned path and "the idea of changing that track is not something we are interested in right now."

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Anatomy class makes science pop at Pacheco High

As two high school girls sat down in their anatomy class last week, they could not wait to pick up a scalpel and dig into a cow's eye.

Pacheco High School, which has a junior class for the first time this year, added an anatomy class to its selection of science offerings for upperclassmen.

"We were going through the eye, looking at all the parts: the cornea, the retina and the iris," said junior Brianna Magana after the dissection.

Magana's lab partner Aleena Mathew said the idea was to compare the cow's eye to a human eye. She said the anatomy students have already sliced up a sheep's brain this year.

"That was pretty cool," Mathew said.

As a whole, American students lag in the fields of science and math. They scored 23rd in math, behind Lichtenstein and Singapore, and 31st in science, behind Estonia and Hungary, when compared with 65 other top industrial countries.

Anatomy teacher Jennifer Brock said those subjects have a stigma of being hard and are often intimidating to students. However, her class has a dozen students and most of them are headed into science or medical fields in college.

"In this school district, we push science and math as much as we can," Brock said.

Brock said the anatomy class is always popular at Los Banos High, so it was an easy decision to bring it to Los Banos Unified School District's newest high school.

Grace Taylor, an assistant principal, sees upperclassmen in science classes as a victory.

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Anatomy class makes science pop at Pacheco High

Anatomy of a road closure

graphic

Ever wondered what goes on behind the scenes of a major road event?

As Sydney recovers from another Mardi Gras hangover, a group of traffic experts is already planning road closures and logistics for next year's event.

"We'll debrief from an event the next day, and then start planning the next year's event straight away," says Brendan McNally, senior major events planner at the Transport Management Centre.

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The centre is responsible for managing traffic flows at all major events in Sydney, from last week's parade to the Sydney Marathon and City2Surf.

It coordinates the efforts of all the interested parties in a big event, from the event organisers to NSW Police and emergency services, the State Transit Authority, RailCorp and Sydney Ferries.

"Beyond that, it's basically anyone who has an interest, and depending on the location the negotiations could include the City of Sydney council, Centennial Park, the Royal Botanical Gardens, or the Sydney Harbour Foreshore Authority,"Police Inspector Paul Carrett from the State Planning Unit says.

With this year's Mardi Gras attracting 9000 people in the actual parade, roughly 1000 volunteers, and an estimated 150,000 spectators, the potential for something to going pear-shaped is obvious.

The Mardi Gras Parade has followed the same route for decades, but the details of the road closures around the route are always up for consideration.

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Anatomy of a road closure

Is It the End for Grey's Anatomy's Owen and Cristina?

Sandra Oh

Uh oh! It looks like bad news for fans who hope that Grey's Anatomy docs Owen Hunt (Kevin McKidd) and Cristina Yang (Sandra Oh) can still save their marriage.

"It's just sad and hard right now," Oh told TV Guide Magazine at Sunday's L.A. benefit for Mariska Hargitay's Joyful Heart Foundation which supports survivors of sexual assault, domestic violence and child abuse. "If there's [hope], I can't see it right now."

In the episode that aired Feb. 23, Cristina started to suspect that Owen was having an affair, and those suspicions will continue in the March 15 episode, "One Step Too Far."

"What I really am happy with, is that a dissolution of a relationship if it is a dissolution takes a long time and is painful. We're spending time with them, seeing it happen," says Oh. "And not quickly, but painfully, day by day."

"It's real, it's messy and it's also why we root for them so much," adds costar Kim Raver. Though Raver's character, Teddy, has currently written off her friendship with Owen, there seems to be a glimmer of hope that the former best friends may reconcile. "In terms of Teddy and Owen, the rift is so dramatic that maybe that walk back home hopefully will be an interesting journey," Raver says. "That's what's interesting to me about the relationship now."

Oh also says that the subject of sexual assault will come up in an future episode, and the entire cast will be involved. "We're dealing with a very dramatic side of this issue," she says. "I really admire Mariska and her work, not only on her show and the influence and the impact that she has on the show for this work, but it translates also in our work on Grey's Anatomy."

"It touches all of us, even if we don't know that it does," adds Raver. "I think the fact that we're discussing it is the first step to aiding it."

Subscribe to TV Guide Magazine now!

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Keck's Exclusives: Grey's Anatomy Boss on Who'll Be Back – and Who Won't!

Shonda Rhimes

Grey's Anatomy/Private Practice creator Shonda Rhimes has plenty to sing about. Her new ABC series, Scandal, debuts April 5; she's got several pilots in the works; and most of the Grey's cast is taking part in the March 18 musical charity event (held at UCLA): "Grey's Anatomy: The Songs Beneath the Show," benefiting The Actors Fund. Even more exciting, she's confident all our favorites (yes, that includes Patrick Dempsey and Ellen Pompeo) want to return for Season 9.

TV Guide Magazine: How did "Grey's Anatomy: The Songs Beneath the Show" come about? Rhimes: When we did the musical episode last season, we discovered we had way more singing talent than we ever imagined. The entire cast with the exception of Patrick and Ellen and Jesse Williams, who has a prior commitment is on board and pretty excited.

TV Guide Magazine: Why no Patrick and Ellen? Rhimes: I'm not sure. I threw it out there "If you're free and available, this is what we're going to do." Sara Ramirez, Kevin McKidd, Justin Chambers, Chyler Leigh and Jessica Capshaw are all going to sing. Sandra Oh has stated she's not a singer, so she'll do a couple special things. [Eric Dane, Sarah Drew, James Pickens Jr., Kim Raver and Chandra Wilson will also take the stage.]

TV Guide Magazine: You must know by now if Patrick and Ellen will be back next season. Rhimes: I have no idea. I have my fingers crossed. What I think is really lovely is that everybody wants to come back. There's [money] stuff happening. I am [confident], but I have a plan in place for the finale that can occur regardless of who is staying. Our goal is to have Derek and Meredith move in to the completed dream house. [A real L.A. home will be used.] And our residents will be interviewing for jobs all around the country.

TV Guide Magazine: Katherine Heigl recently said she wants to come back to "see where Izzie is." Is she welcome? Rhimes: I think it was really nice to hear her appreciating the show. We are on a track we have been planning, and the idea of changing that track is not something we are interested in right now.

TV Guide Magazine: Switching gears to Private Practice, tell me you're going to finally give Addison a baby? Rhimes: That journey is going to be completed by the time the season is over, and I think fans will be very satisfied.

Subscribe to TV Guide Magazine now!

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Keck's Exclusives: Grey's Anatomy Boss on Who'll Be Back – and Who Won't!

The Alliance for Regenerative Medicine Statement on Use of Cell Therapies Not Approved by the Federal Drug …

WASHINGTON, DC--(Marketwire -03/05/12)- The Alliance for Regenerative Medicine issued the following statement today: "An article about stem cell treatments taking place in Texas published by Nature last week is extremely troubling. The article suggests that patients are being administered stem cell treatments that have not been systematically demonstrated to be safe and effective therapies through the established FDA regulatory process.

"Cell therapy treatments, including those using adult stem cells, hold the promise of providing patients with treatments and cures for numerous diseases and disabilities. However, FDA regulation is key to ensuring that the treatments available to patients are safe and effective.

"The Alliance for Regenerative Medicine (ARM), a non-profit organization whose mission is to promote increased funding and development of regenerative medicine products, believes cell therapy and regenerative medicine products, including autologous cell therapy products, must go through the rigorous safety testing that is part of the FDA regulatory process before they can be marketed to the public. These regulations are designed to promote safe collection, manufacture, storage, and use of human cells, and cellular and tissue based products. ARM members comply with these rules because they know that FDA oversight helps to prevent patients from exposure to potentially unsafe products.

"We urge all companies developing stem cell treatments to follow FDA rules governing research and product development. ARM remains committed to working with all stakeholders to ensure that safe and effective products reach patients as soon as possible."

About The Alliance for Regenerative Medicine (ARM) The Alliance for Regenerative Medicine (ARM) is a Washington, DC-based non-profit organization that promotes legislative, regulatory, reimbursement, and financing initiatives necessary to facilitate access to life-giving advances in regenerative medicine. ARM also works to increase public understanding of the field and its potential to transform human healthcare, and provides services to support the growth of its member companies and organizations. To learn more about ARM or to become a member, visit http://www.alliancerm.org.

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The Alliance for Regenerative Medicine Statement on Use of Cell Therapies Not Approved by the Federal Drug ...

Nutrition Night gives Belding students insights to health

Students and parents in Belding will be able to become aware of just how important healthy habits are at this years Nutrition Night, which is scheduled for 5 p.m. Thursday.

The free event, geared toward middle school and high school students, will take place at Belding High School and feature a variety of activities, including speakers, vendors and informational seminars.

One of the speakers includes Mike Church, who is a musician, food columnist and chef at Calvin College. He said he will be promoting healthier eating habits, teaching attendees how to properly read food labels and know serving sizes, and discussing organic and natural food products.

Church said he decided to present at Nutrition Night because he wanted to spread awareness about healthy eating and because it will also be something he is not used to doing.

Im always looking for a challenge, and its a good way to give some great information to students, said Church. Im going to try to just make it fun and simple.

He said he will be demonstrating quick and easy ways to make smoothies that are not only pleasing to the palette, but provide a good source of protein.

Church added he realizes how tough it can be for students to get good sources of nutrition for personal brain fuel, and will give them a few new options to try in the morning besides sugary cereal.

It can make a world of difference, Church said.

Bodybuilders Dave Doolittle and Todd Davis will also be in attendance, speaking about how important nutrition is in terms of learning, brain function and physical activity. Both have been in the body building world for more than 15 years and have won multiple championships.

Doolittle said he will also discuss his drug free bodybuilding career, emphasizing that some, more unhealthy ways for achieving dreams can be harmful.

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Nutrition Night gives Belding students insights to health

Tips from the journal mBio

Public release date: 5-Mar-2012 [ | E-mail | Share ]

Contact: Jim Sliwa jsliwa@asmusa.org 202-942-9297 American Society for Microbiology

Life on a Dead Deep-Sea Vent

When a deep-sea thermal vent goes cold and dormant the microbial life around it does not just stop. Instead, it adjusts and picks up the slack according to researchers from University of Southern California (USC) in the current issue of mBio, the online open-access journal of the American Society for Microbiology.

A hydrothermal vent is a fissure in a planet's surface from which geothermally heated water issues. The area around deep-sea hydrothermal vents is relatively more biologically active than other areas on the ocean floor and scientists have been studying the microbial diversity around these vents since the 1970s. Katrina Edwards and her colleagues from USC and the University of Minnesota chose to study the microbial communities surrounding inactive vents and found some striking differences.

They found that the microbes that thrive on hot fluid methane and sulfur spewed by active hydrothermal vents are supplanted, once the vents go cold, by microbes that feed on the solid iron and sulfur that make up the vents themselves. Scientists have long known that active vents provided the heat and nutrients necessary to maintain microbes, but dormant vents were once thought to be devoid of life.

http://mbio.asm.org/content/3/1/e00279-11

New Genomic Data Could Aid Rapid Detection of Hospital Infections

Enterococci bacteria, and in particular vancomycin-resistant enterococci, have emerged as a leading cause of multidrug-resistant hospital-acquired infections. Key to treating and controlling these infections is rapid identification of the pathogen and treatment with the appropriate antibiotics to be effective.

Researchers from Harvard Medical School and The Broad Institute report new genomic sequencing data that can help aid in the advance detection of pathogenic enterococci. They report their findings in the current issue of mBio, the online open-access journal of the American Society for Microbiology.

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Tips from the journal mBio

VCU study: Bad environment augments genetic risk for drug abuse

Public release date: 5-Mar-2012 [ | E-mail | Share ]

Contact: Sathya Achia Abraham sbachia@vcu.edu 804-827-0890 Virginia Commonwealth University

RICHMOND, Va. (March 5, 2012) The risk of abusing drugs is greater even for adopted children if the family environment in which they are raised is dysfunctional, according to a new study conducted by a collaborative team from Virginia Commonwealth University and Lund University in Sweden.

Previous research suggests that drug abuse is strongly influenced by a mix of genetic factors and the environment, including influences of family and peers. That research is primarily based on twin studies and typically involves families that are intact. Relatives that share genes and environment make it difficult to determine if the family dysfunction is linked to the drug abuse or if it is genetics at play. There have been no large-scale adoption studies performed to verify the findings, until now.

In the study, published online March 5 in the journal Archives of General Psychiatry, researchers examined how genetic and environmental factors contribute to the risk for drug abuse in adoptees. Using a large and representative adoption sample from Sweden, they demonstrate that genetic factors played a moderate role in the liability to drug abuse.

"For an adoptee, having a biological parent with drug abuse who did not raise you doubles your risk for drug abuse," said first author Kenneth Kendler, M.D., director of the VCU Virginia Institute for Psychiatric and Behavioral Genetics.

"But we also found an important role for environmental factors. If you have an adoptive sibling - with whom you have no genetic relationship - develop drug abuse, that also doubles your risk for drug abuse,"

More importantly, according to Kendler, the team showed that the impact of your genes on risk for drug abuse is much stronger if you are raised in a high-risk rather than a low-risk environment.

"A bad environment can augment the effect of genetic risk on drug abuse," he said.

Kendler, professor of psychiatry, and human and molecular genetics in the VCU School of Medicine, and a team of researchers from Lund University led by Jan Sundquist, M.D., Ph.D., professor and director of the Center for Primary Health Care Research, and Kristina Sundquist, M.D., Ph.D., professor of family medicine at the Center for Primary Health Care Research, analyzed nine public registry data sets compiled between 1961 and 2009 of adoptees and their biological and adoptive relatives from Sweden.

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VCU study: Bad environment augments genetic risk for drug abuse

DNA found on shotgun belonged to murder victims

Posted at: 03/05/2012 5:51 PM By: Mark Mulholland

FORT EDWARD -Testimony in the Matthew Slocum murder trial onMonday revolved mostly around blood and DNA recovered from evidence.

State Police DNA expert Daniel Myers testified about the presence of DNA on Loretta Colegrove's blood spattered tank top. Myers told the jury that the blood belonged to murder victim, Lisa Harrington.

Myers was also asked about the presence of DNA on the suspected murder weapon, a 12-gauge shotgun. He testified that it had Lisa and Dan Harrington's DNA, and someone else's, but tests couldn't determine whose it was.

According to Myers, only one piece of evidence had Slocum's genetic material: a cellphone that belonged to murder victim Josh O'Brien.

The phone was found under the porch in New Hampshire where Slocum was allegedly hiding out after the July 13th murders and arson.

A New Hampshire state trooper testified to finding the phone and other items, including several knives, prosecutors say were taken from the Turnpike Road home by Slocum.

A New York State Police investigator testified about the location along Massachusetts State Route 2 where some of Dan and Lisa Harrington's guns were found.

Inv. Tim Northrup identified nine weapons that were recovered from the woods in the Town of Florida, allegedly dumped there by Slocum and Colegrove.

Testimony ended when a CPS caseworker told the jury that Slocum told her Colegrove had nothing to do with the murders.

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DNA found on shotgun belonged to murder victims

Posted in DNA

Biology Lab Project: Dissecting Maestro Roger Federer's Forehand

Roger Federer's game can be described in many ways, but one word comes to my mind: classy.

I've been a Federita since I started tennis and have been so fortunate to see pretty much every single one of his matches.

Every part of his game is so technically sound that it is unreal.

First, and foremost, let us uncover the Federer forehand to see what secrets it holds.

We will see the old and new class of tennis within just a single one of his strokes.

The grip

Roger plays with a modified version of the Eastern grip.

Everyone these days is taught to play with a semi-Western grip: I was taught it by my third year of playing.

It was a shock at first, but now I absolutely love it because I can easily flatten it out or put even more spin on the ball whenever I like.

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Biology Lab Project: Dissecting Maestro Roger Federer's Forehand

Penn Biochemist Receives Hodgkin Award from The Protein Society

PHILADELPHIA Mark A. Lemmon, PhD, chair of the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania, is the 2012 recipient of the Dorothy Crowfoot Hodgkin Award by The Protein Society. The award will be presented at the 26th Annual Symposium of The Protein Society in August, during the Plenary Awards Session.

The Dorothy Crowfoot Hodgkin Award, is given in recognition of exceptional contributions in protein science, which profoundly influence our understanding of biology. Dr. Lemmon is being recognized for major contributions to the field of signal transduction and transmembrane signaling mechanisms of receptor tyrosine kinases. Crystallographic, biochemical, and genetic studies from his laboratory have provided sophisticated understanding of EGFR cell signaling. His discoveries of the mechanisms for the epidermal growth factor receptor family offer new ideas for developing therapies targeting cancer and other human diseases.

"Of course, it's not really my work that this award honors, but really that of several fantastic Penn postdocs and students," says Lemmon. "First, I'd particularly like to single out Diego Alvarado, Daryl Klein, Sung Hee Choi, Jeannine Mendrola and Fumin Shi for the EGF receptor work that the award cites. They are all great examples of the superb scientists that Penn Medicine attracts and reasons why it's so great to be here.

"Second, Dorothy Crowfoot Hodgkin has always been a hero of mine. She did much of her secondary education in the part of England where I grew up and was already a legend at Oxford when I went there. Her crystallographic studies of insulin -- well after her 1964 Nobel Prize -- inspired much of our structural work in EGF signaling. I always found it interesting too given her politics - that Margaret Thatcher was one of Professor Hodgkin's most famous students."

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Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $4 billion enterprise.

Penn's Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools and among the top 10 schools for primary care. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $507.6 million awarded in the 2010 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top 10 hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2010, Penn Medicine provided $788 million to benefit our community.

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Penn Biochemist Receives Hodgkin Award from The Protein Society

Anatomy of a Government Phone, or, Can the NSA Build an Android?

The craziest thing about a typical "top secret" U.S. Government phone is that you can probably spot it from a football field away. If your mental picture of a Hollywood-style NSA agent drives a black AMC Ambassador, wears a polyester suit and Ray-Bans, and smokes Luckies, then his phone may either be Maxwell Smart's shoe or a General Dynamics Sectera Edge (pictured left). At any distance, it looks like one of the pocket football games my junior high school vice principal used to confiscate and collect in his back drawer.

The National Security Agency wants a real-world smartphone, not the one it has now - not the one you see here. Of course, it must fulfill the Dept. of Defense's requirements for session encryption and data retention. But beyond that fact, the NSA wonders why its secure phone can't have multitouch, apps, and speed just like the civilians have. Based on looks alone, you'd think the civilians are a couple of pegs ahead of the G-men. This is a story of looks being more deceptive than even a security agency could have anticipated.

The real face of the National Security Agency looks more like Margaret Salter. At the RSA Conference in San Francisco last Wednesday, Salter told attendees the story of the NSA's Secure Mobility Strategy. She leads a department called the Information Assurance Directorate. For the better part of four decades, IAD has been tasked with securing secret government communications, and building specifications for the tools to do it. The NSA contracts with private suppliers to build a class of devices it calls GOTS (government off-the-shelf). The gestation cycle for each of these devices - from the conceptual stage, to development, to deployment - typically consumes years. Perhaps the best-known GOTS product is still in wide use today - 1987's STU-III secure telephone, which looks about as home on an agent's desk today as an IBM PC.

Still, as Salter told the RSA attendees, for the better part of half a century, the NSA explicitly defined its own market, a private universe of products made for its own exclusive consumption. "That was cool for us, for the longest time. We kinda had a monopoly on this from the very beginning," she remarked. "We were mostly building things like radios for combat, [and] big link encryptors to hook one site up to another site."

But their ease of use ranked right up there with a World War II cipher machine. "Once you get something in the hands of an individual user who's not a cleared COMSEC custodian, someone who knows what they're supposed to be doing with this stuff and understands all the details, ease of use became incredibly freakin' important. And it turned out that, although our stuff was incredibly secure, it was not incredibly easy to use."

Over time, it became more difficult over time for the agency to define "ease of use" on a comparative scale. In just the last five years, the consumer universe appeared to leave the NSA's secure market behind. "The world everyone wants is, I want to get what I want, when I want it, where I want it."

Salter's team considered whether it was feasible for NSA to utilize a real, commercial smartphone - one like all the kids are using nowadays - but with software that made the device perhaps more secure than the Sectera Edge. "The phones are so popular and exploding all over the place, because we can play Angry Birds on them, and do whatever you want. But we needed enterprise management - some control over it, because honestly, we didn't really want you to be able to go load Angry Birds on your TS [top secret] phone... That was not a business model that we could support, or even defend."

They launched Project Fishbowl, a pilot to produce a smartphone made of mostly commercial parts and infrastructure (more COTS than GOTS), capable of supporting classified voice and data, while remaining as easy to use as its civilian counterpart and staying inexpensive. The historical significance of the NSA embracing commercial crypto standards cannot be stressed enough. Anyone familiar with how RSA came to be in the first place will recall the fights its engineers faced keeping the government from classifying it, taking its power out of the public's hands. Perhaps the whole point of the RSA standard and the RSA conference is to promote the power of security for everyone through manageable encryption.

"So one of the things I harp on most is, why was that so hard?" remarked Salter.

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Anatomy of a Government Phone, or, Can the NSA Build an Android?