Memory problems may increase after being hospitalized

Public release date: 21-Mar-2012 [ | E-mail | Share ]

Contact: Rachel Seroka rseroka@aan.com 651-695-2738 American Academy of Neurology

ST. PAUL, Minn. A new study suggests that older people may have an increased risk of problems with memory and thinking abilities after being in the hospital, according to research published in the March 21, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

"Our study is timely as the United States population continues to rapidly age and researchers try to identify factors that could reduce memory and thinking problems in the elderly," said study author Robert S. Wilson, PhD, of Rush University Medical Center in Chicago. "Understanding a possible link to something as common as hospital stays is extremely important."

The study involved 1,870 people over the age of 65 who lived in Chicago and were interviewed every three years for up to 12 years to test their memory and thinking skills. Of those, 1,335 people, or 71 percent, were hospitalized at least once during the study.

On average, elderly people's scores on tests of memory and thinking skills decline slightly as they age. In the study, researchers found that people's overall scores declined twice as fast after a first hospital stay, compared either to their previous rate before the hospital stay or to people who were not admitted to the hospital. On specific tests, the rate of decline after the first hospital stay was more than three times faster on a long-term memory test and 1.5 times faster on a complex attention test. The results stayed the same even after considering factors such as severe illness, longer hospital stay and older age.

"Further research may help to develop strategies to prevent medical problems in older people that lead to hospital stays. It could also lead to changes in hospital inpatient and discharge policies," said Wilson.

###

The study was supported by the National Institutes of Health and the National Institute on Aging.

To learn more about dementia, visit http://www.aan.com/patients.

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Memory problems may increase after being hospitalized

Nanotechnology for Drug Delivery: Global Market for Nanocrystals

NEW YORK, March 21, 2012 /PRNewswire/ --Reportlinker.com announces that a new market research report is available in its catalogue:

http://www.reportlinker.com/p0799333/Nanotechnology-for-Drug-Delivery-Global-Market-for-Nanocrystals.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology

Nanocrystals will account for 60% of a $136 billion nanotechnology-enabled drug delivery market by 2021. We forecast the total market size in 2021 to be US$136 billion, with a 60/40 split between nanocrystals and nanocarriers respectively.

Since we now understand that most (if not all) biological processes occur at the nanoscale, the application of life science principles studying the causes of biological phenomena at the molecular level means that medical and biomedical research is increasingly using a bottom-up (rather than the top-down) approach.

One of the biggest challenges researchers face when developing a new drug is how to maximise its solubility in the body. Poor solubility in water correlates with poor bioavailability, which in turn leads to poor delivery. Nanocrystals are ground in special mills producing nano-sized drugs, which are applicable intravenously as nanosuspensions. This procedure enhances the surface/volume-ratio and thus the solubility and bioavailability of most insoluble pharmaceuticals.

The low bioavailability resulting from traditional oral and intravenous drug delivery methods and the market forces at work in the pharmaceutical industry where patents expire after a relatively short period of time unless a novel form of drug delivery is developed that will extend the patent are two major forces that will fuel the growth of the nano tech enabled drug delivery market.

The healthcare market is changing. We are seeing a paradigm shift away from blockbusters and a 'one-size fits all' approach to a more personalised medicine based on an individual's unique genome and immune response. The more scientists learn about the molecular causes for disease the more targeted and effective nanotechnology-enabled drug delivery therapies will become.

EXECUTIVE SUMMARY 10

CHAPTER 1 - INTRODUCTION 15

REPORT SCOPE 15

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Nanotechnology for Drug Delivery: Global Market for Nanocrystals

Auburndale centenarian donates DNA to study

For Erna Rosenberg, it's a mystery what's led to her long life.

Now a group of scientists are hoping that Rosenberg's DNA, along with that of other centenerians, holds clues to solving that mystery.

Rosenberg, who turned 100 in July, is one of about 100 with at least a century of life experience including the oldest person in the world 115-year-old Besse Cooper - who have donated samples of their DNA to scientists competing in the $10 million Archon Genomics X prize competition by Medco, a New Jersey-based health care and research company.

I think its a family thing. But I have no one to ask now, Rosenberg said in her Lasell Village apartment in Auburndale. I dont really know, but Im here and thats amazing.

The New York City-born Rosenberg has never had cancer or fought off any other life-threatening diseases. She lived most of the ten decades of her life without suffering any serious illnesses, but was recently diagnosed with a heart valve problem and uses an oxygen tube to help with her breathing.

The curly white-haired lady suspects that her longevity is due to good genes on her mothers side of the family. Her mother lived into her late 80s, Rosenberg said. Her father died in his 70s of heart problems, she said.

My sister, the one who committed suicide, she wouldve had those genes too, Rosenberg said. Then I have a niece who is my sisters daughter. Shes 70 now and shes in perfect health and we laugh about it.

Grant Campany, senior director and prize lead of Archon Genomics, said when the 100 human genomes are sequenced the information will be provided to researchers around the world with the hope that it improves the practice of medicine.

Theres a lot of inefficiencies in how medicine is currently practiced, he said. Medicine is really practiced through trial and error. Basically, you get a physician asking you a series of questions. In most cases, when they do make a diagnosis, they prescribe you a medication and often times those arent effective.

But Campany said creating a genetic sequence could help change the future of medicine by helping patients understand the best course of treatment.

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Auburndale centenarian donates DNA to study

Families can enroll now in UB's free weight loss program for children and parents, one of the nation's most successful

News Release

"Because we simultaneously treat obese parents and children with the same program, the benefits extend to the rest of the family, too," says UB's Epstein.

Download JPEG

Release Date: March 14, 2012

BUFFALO, N.Y. Obesity in childhood can create serious compromises to physical and mental health and longevity, but parents who want to encourage healthier eating face significant challenges.

Now, a free, weight-loss program developed at the University at Buffalo, one of the nation's only programs proven to achieve and maintain long term (10 years) weight loss in children is enrolling Western New York families. The program is funded by the National Institutes of Health.

To be eligible, children must be overweight and between 8 and 12 years of age, considered the best age to intervene in creating healthy eating habits; they also must have at least one parent who is overweight.

Nearly 1 in 3 children in the US are now overweight or obese, says Leonard H. Epstein, PhD, SUNY Distinguished Professor of Pediatrics in the UB School of Medicine and Biomedical Sciences and professor and director of the UB program. "The number has doubled in the last 20 years and it keeps increasing. At the same time, nearly 2 out of 3 adults are overweight and 1 of 3 adults in the US is also obese."

Clearly, engaging in behaviors that encourage healthy eating and more physical activity is a tougher challenge than it used to be, Epstein continues. "Children today are faced with many more opportunities for unhealthy eating than they were just twenty years ago. There are many more high-calorie foods available. Portion sizes in restaurants are larger now and children have more opportunities to be sedentary than they used to have."

In spite of these challenges, UB's Buffalo Childhood Weight Control program has shown consistent success. That's because the UB program is one of the nation's very few childhood obesity programs that is evidence-based -- that is, based on the best available evidence from peer-reviewed scientific data. Those data, generated by prominent obesity researchers at UB and elsewhere, have long shown that treatment programs like UB's, involving both parent and child, are the single most effective way to achieve healthy weight in children.

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Families can enroll now in UB's free weight loss program for children and parents, one of the nation's most successful

'Highlander' Director Views 'Immortality As A Curse'

In "Intruders," director Juan Carlos Fresnadillo explores the ideas of fear and losing control. For his next film potentially his next film, I should say he'll dive into another form of horror: the possibility of living forever.

Immortality sounds glamorous to most, sure, but not to Fresnadillo not in his vision of "Highlander," at least. The "28 Weeks Later" filmmaker is set to pick up the sword and bring "Highlander" back to the big screen for Summit Entertainment, and in his mind, it's the difficulties of everlasting life that's most interesting about the fantasy franchise.

"The idea about immortality as a curse, you know?" Fresnadillo answered when MTV News asked him about his attraction to "Highlander." "Immortality is a very difficult time in your life, if you become an immortal. If you think about that, it's impossible to be in love with anyone you're growing, you're getting old, as a human, but not as an immortal. I think immortality could be a very lonely feeling [worth exploring]."

Still, Fresnadillo isn't entirely sure that "Highlander" is the next film on his increasingly busy plate. "I'm working hard on that project," he offered. "We'll see if finally it's my next movie."

One thing he definitely won't be working on, however, is "The Crow." Fresnadillo was attached to direct a reboot of the James O'Barr graphic novel at one point in time, before ultimately bowing out in October. It's a shame; anyone who sees "Intruders" will agree that based on the opening scene alone, Fresnadillo would have been an inspired choice to breathe new life into "The Crow," if the legendary film even needs to be remade in the first place. (Hint: it doesn't.)

"It's difficult to explain to you," the director said of what his vision for "The Crow" would have been. "When you're working in this industry, you're dealing with many projects at the same time. 'The Crow' was one of them. It was a very cool concept to make some new approach and new refreshment of the idea, but I didn't have the time to explore it too much. I didn't have time to say, 'Here's the vision of what I think would be fantastic for that.'"

Are you looking forward to Fresnadillo's "Highlander" remake? Are you disappointed that he won't bring "The Crow" to life? Tell us what you think in the comments section or hit us up on Twitter!

Tags Highlander, intruders, Juan Carlos Fresnadillo, the crow

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'Highlander' Director Views 'Immortality As A Curse'

Survey shows Kanawha County parents want sex education in schools

Although a majority of Kanawha County parents with school-aged children say sexual education should be taught in schools, a quarter say they're not even sure they're child is learning anything about human reproduction.

The findings are a result of a Public Policy Polling survey conducted in July 2011. The poll surveyed 260 parents via telephone. Sixty-eight percent of respondents said sex education should be taught in West Virginia schools, while 25 percent said no and 7 percent said they weren't sure. Of those surveyed, 53 percent said sex education was taught in their school district while 21 percent said no and 25 percent said they weren't sure.

"Public support for sex education in public schools is very strong," said Kira Miskimmin, public affairs coordinator for Planned Parenthood Health Systems West Virginia. "we know that sexual health education is critical to our young people. It's critical to helping them lead healthy lives and critical to helping them make informed decisions that will allow them to chart the course of their livesto get an education, choose their careers, to plan a family, you name it."

Miskimmin pointed out that some people view sex education in schools as inappropriate or controversial. However, she pointed out that medical and evidence-based sexual education curriculum is informative and helps teens make better decisions about their sex lives.

"The fact is, the vast majority of Americans support teaching medically-accurate, age appropriate sexual health education to young people in schools," she said.

In addition to the Kanawha County poll, nationally-conducted polls also show that parents want their children to learn about sex in schools.

The poll comes at a time when West Virginia is experiencing the highest teen birth rate in the country. According to a Centers for Disease Control and Prevention study released last fall, West Virginia was the only state to see an increase in the teen birth rate. Between 2007 and 2009, the birth rate among 15 to 17-year-olds shot up 17 percent, according to that survey.

"Lack of access to health care information and services, high rates of teen and unplanned pregnancy and poor sexual health have very real and often long-term consequences for individuals and communities as well," Miskimmin said. "Unfortunately, West Virginia is not immune to these issues or the social and economic costs that go along with this issue."

Miskimmin called the CDC study "absolutely alarming," but pointed out that more people and groups, such as Planned Parenthood and West Virginia Free, are more tuned in to the issue and ready and willing to do something about it. The federal government has provided a new funding stream to provide sexual health education and programs to reduce teen pregnancy.

"When you think about all of that, we do have a lot of opportunity before us," she said. "We have the opportunity to come together, to educate our teens and give them the tools they need to really chart their futures."

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Survey shows Kanawha County parents want sex education in schools

Autism risk gene linked to differences in brain structure

ScienceDaily (Mar. 21, 2012) Healthy individuals who carry a gene variation linked to an increased risk of autism have structural differences in their brains that may help explain how the gene affects brain function and increases vulnerability for autism. The results of this innovative brain imaging study are described in an article in the groundbreaking neuroscience journal Brain Connectivity, a bimonthly peer-reviewed publication from Mary Ann Liebert, Inc. The article is available free online at the Brain Connectivity website.

"This is one of the first papers demonstrating a linkage between a particular gene variant and changes in brain structure and connectivity in carriers of that gene," says Christopher Pawela, PhD, Co-Editor-in-Chief and Assistant Professor, Medical College of Wisconsin. "This work could lead to the creation of an exciting new line of research investigating the impact of genetics on communication between brain regions."

Although carriers of the common gene variant CNTNAP2 -- identified as an autism risk gene -- may not develop autism, there is evidence of differences in brain structure that may affect connections and signaling between brain regions. These disruptions in brain connectivity can give rise to functional abnormalities characteristic of neuropsychological disorders such as autism.

Emily Dennis and coauthors from UCLA School of Medicine and UCLA (Los Angeles, CA) and University of Queensland and Queensland Institute of Medical Research (Brisbane, Australia), used a sophisticated imaging technique to study the brains of healthy young adults who are carriers of CNTNAP2.

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The above story is reprinted from materials provided by Mary Ann Liebert, Inc./Genetic Engineering News.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Autism risk gene linked to differences in brain structure

Europe Clinical Chemistry & Immunodiagnostics Markets Discussed in New Report Published at MarketPublishers.com

LONDON--(BUSINESS WIRE)--

Due to a number of factors like new and more stringent regulations; advances in diagnostic technologies, system engineering, automation, and IT; as well as intensifying competition, the clinical chemistry and immunodiagnostics markets are undergoing significant changes. Some segments, such as routine chemistry, start resembling commodity markets, where product positioning and cost per test are more critical than underlying technology. All these upcoming transformations in the marketplace are expected to provide amazing opportunities for a variety of new instruments and reagent systems, as well as auxiliary products, like specimen preparation devices, controls, calibrators.

New research report The 2012 European Clinical Chemistry and Immunodiagnostics Markets: France, Germany, Italy, Spain, UK - Emerging Opportunities and Business Expansion Strategies developed by Venture Planning Group (VPG) explores future marketing and technological trends in five major Europeancountries (France, Germany, Italy, Spain and the UK) and Japan; provides estimates of the specimen, test and sales volumes, as well as major suppliers' sales and market shares; compares features of leading analyzers; profiles top market players; and identifies specific product and marketing opportunities facing suppliers during the next five years.

Companies mentioned in the report include: Abbott Laboratories, AdnaGen, Ambrilia, AMDL, Beckman Coulter, Biomedical Diagnostics, BioMerieux, Bio-Rad, Canag Diagnostics, Dako, DiaSorin, Eiken, Fujirebio, Instrumentation Laboratory, J&J, Kyowa Medex, Matritech, Roche, Siemens, Sysmex, Thermo Fisher, Trinity Biotech, Tosoh, Wako, and Wallac.

Report Details:

Title: The 2012 European Clinical Chemistry and Immunodiagnostics Markets: France, Germany, Italy, Spain, UK - Emerging Opportunities and Business Expansion Strategies Published: March, 2012 Pages: 900 Price: US$ 18,500

http://marketpublishers.com/report/medicine_pharmaceuticals_biotechnology/drugs_biotechnology/2012_european_clinical_chemistry_n_immunodiagnostics_markets_france_germany_italy_spain_uk_emerging_opportunities_n_business_expansion_strategies.html

Report Contents:

INTRODUCTION

WORLDWIDE MARKET AND TECHNOLOGY OVERVIEW A. Major Routine Chemistry Tests 1. Albumin 2. Alkaline Phosphatase 3. ALT/SGPT 4. Ammonia 5. Amylase 6. AST/SGOT 7. Bilirubin 8. Blood Gases 9. Blood Urea Nitrogen (BUN) 10. Calcium 11. Cholesterol 12. Cholinesterase 13. Creatinine 14. Electrolytes a. Carbon Dioxide/Bicarbonate b. Chloride c. Potassium d. Sodium 15. Fructosamine 16. Gamma-Glutamyl Transpeptidase (GGT) 17. Glucose 18. High Density Lipoprotein (HDL) 19. Iron 20. Lactate Dehydrogenase (LDH) 21. Magnesium 22. Phosphorus 23. Protein 24. Triglycerides

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Europe Clinical Chemistry & Immunodiagnostics Markets Discussed in New Report Published at MarketPublishers.com

Proctor chemistry students participate in March Madness

Studentsin Mary Ann Mazzolas chemistry class at Proctor High School in Utica are among 10,000 high school students in the United States who are experiencing their own March Madness as they participate in local Chemistry Olympiad competitions the first step toward securing a spot on the U.S. Chemistry Olympiad team.

Later this summer, the team will go up against chemistry students from 70 other nations at the 44th International Chemistry Olympiad outside Washington, D.C.

Next month, Mazzolas top two chemistry students will go on to take the U.S. National Chemistry Olympiad national exam with the top two students from all other participating high schools in the country.

Selection for the national exam is based on scores in the local competition and teacher recommendations. The top 20 students from the national competition are then invited to a two-week intensive study camp held in June at the U.S. Air Force Academy in Colorado Springs.

At the camps conclusion, the final four students are chosen to represent the United States at the International Chemistry Olympiad, where they compete with the worlds most talented high school students for gold, silver and bronze medals.

The local examinations consist of 60 multiple-choice questions representing a fairly wide range of difficulty, usually completed in 110 minutes. The three-part, 4.5-hour national exam includes multiple-choice questions, problem solving and a lab.

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Proctor chemistry students participate in March Madness

Thomas Jessell Receives 2012 Gairdner Award for Groundbreaking Insights on Nervous System

Published: March 21, 2012

The Gairdner Foundation has announced the recipients of the 2012 Canada Gairdner Awards. Recognized for some of the most significant medical discoveries from around the world, this years winners showcase a broad range of new medical insights, from pioneering new ways to tackle childhood illness in developing countries to identifying how our biological clocks guide our everyday lives.

Among the worlds most esteemed medical research prizes, the awards distinguish Canada as a leader in science and provide a $100,000 prize to scientists whose work holds important potential. The 2012 winners are as follows:

Thomas M. Jessell, Ph.D.

Thomas M. Jessell, Ph.D., Howard Hughes Medical Institute, Kavli Institute for Brain Science, Columbia University Medical Center, New York, NY

The challenge: Through communication between the sensory neuron and the motor neuron in our bodies nervous system, we acquire the ability to move and react to the world around us. But little was known about how these neurons communicate with each other.

The work: Dr. Jessells work reveals the basic principles of nervous system communication. By studying the assembly and organization of the circuit that controls movement in the spinal cord nervous system, Dr. Jessell identified the direct connection between the sensory neuron, which is responsible for allowing us to process what is happening in the world around us, and the motor neuron, which allows us to control how our muscles move to react to what we sense in that world.

Why it matters: As a result of this discovery, we have the potential to create interventional strategies to treat and cure neurodegenerative diseases such as Amyotrophic Lateral Sclerosis (ALS) and Spinal Muscular Atrophy (SMA), where a problem with the circuit connection between the sensory neuron and the motor neuron prevents our minds and bodies from reacting properly to what we sense around us. Similarly, we now have the potential to restore movement in patients with spinal cord injury or paralysis.

(To learn more about Dr. Jessell and his work, read The Promise of the Brain.)

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Thomas Jessell Receives 2012 Gairdner Award for Groundbreaking Insights on Nervous System

Anatomy of an ACA Lie – Health Stew – Boston.com

Most good lies have a kernel of truth in them, giving them undeserved credibility. Here's a great example of a lie intended to scare senior citizens into opposing both the Affordable Care Act (aka: ACA/ObamaCare) and President Obama as well.

Last week, I spoke to the GE Oldtimers Association, a luncheon group of about 50 older gents (and a few women) who are retired managers and engineers from the GE jet engine plant in Lynn, Massachusetts. They meet at Anjelica's Restaurant in Middleton, MA. They are nice, smart, informed, and attentive. They had lots of questions about the ACA, and we had a great discussion.

Near the end, some of them asked me about unsolicited emails they were getting claiming that the ACA, beginning in 2013, would impose on them a new Medicare tax of 3.8% when they sold their homes. Now, I knew that the ACA creates a new 3.8% Medicare tax on unearned income in excess of $200,000 for individuals and $250,000 for couples. But a tax on principal residences? It didn't sound right. Rather than guess, I asked them to send me the email and I would check it out.

So here's the email (addresses deleted -- but notice the date, really recent):

From: --- Sent: Sunday, March 11, 2012 10:30 PM To: --- Subject: If you own a home-- Sent from my iPhone Begin forwarded message:

sorry I hate passing this stuff on but its pretty good

Subject: If you own a home--

If you own a home, Please read this. THIS WILL BLOW YOU AWAY !!!!!

The National Association of REALTORS is all over this and working to get it repealed, before it takes effect. But, I am very pleased we aren't the only ones who know about this ploy to steal billions from unsuspecting homeowners. How many REALTORS do you think will vote Democratic in 2012?

Did you know that if you sell your house after 2012 you will pay a 3.8% sales tax on it? That's $3,800 on a $100,000 home, etc. When did this happen? It's in the health care bill and goes into effect in 2013.

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Anatomy of an ACA Lie - Health Stew - Boston.com

The Anatomy of Media Bias: Trayvon Martin, Mike Daisey, and the Press

Julian Sanchez -- Research Fellow, Cato Institute

Like many folks who had seen and been moved by Mike Daisey's powerful monologue "The Agony and the Ecstasy of Steve Jobs," I was profoundly disappointed by the recent revelation that he had not only fabricated some of the work's key scenes, but lied to the journalists and fact checkers at This American Life to prevent them from discovering the deception. There's no point, at this stage, in adding another condemnation to the chorus, but I do want to highlight a pair of sharp pieces by Slate's Daniel Engberger and The Economist's Erica Grieder, responding to the common claim that Daisey's narrative was, as the saying goes, "fake but accurate."

While most commentary on the story has rightly rejected Daisey's invocation of "artistic license" to excuse the use of falsified anecdotes in a work of purported nonfiction, much of it includes the obligatory caveat that Daisey's larger point, the essential picture he paints of labor practices at Chinese suppliers like Foxconn, is true. So, for instance, in his performance, Daisey recounts how in a few hours of interviews outside just a couple of Foxconn plants, he encountered numerous underage workers--girls as young as 12 and 13 years old. Under pressure, he retreated to the claim that he'd spoken (in English) with one girl who identified herself as being 13, and seen several others who "looked young." The translator who accompanied Daisey on these interviews--the one he'd lied to prevent journalists from contacting--denies that there was even the one, and insists that she'd remember if there had been. Now, you don't get a gig as an English translator in China without staying on the good side of the Chinese government, so she might have her own incentive to downplay anything that reflects badly on the labor situation there--but all things considered, I'm inclined to agree with Ira Glass that her account comes across as much more credible than Daisey's.

Suppose we think Daisey probably did just make up this encounter. It's still undeniably the case that there have been underage workers employed by Apple suppliers: The company itself reports identifying 91 in an audit conducted in 2010, the year Daisey visited China. Thus, some argue, even if Daisey lied, the more important thing is that his dramatization reflected the underlying truth in an emotionally resonant way.

I agree with Engberger and Grieder that this line of argument is wrong, and that Daisey's pseudo-anecdote is substantively misleading when you consider what it's really meant to show. Nobody disputes that the number of underaged workers employed by Apple suppliers is greater than zero. But in the context of Foxconn's 300,000-strong workforce, in a country where (as the report suggests) parents are willing to procure fake IDs to help children obtain a coveted factory job, it's also probably not realistic to expect that this would never happen. The real question is whether Apple is making a good faith effort to enforce some screening procedures, identify and correct failures in the process when they occur, and so on.

Daisey's anecdote implicitly makes the far stronger claim that Apple is egregiously, culpably negligent here: Child labor is so prevalent that you scarcely need audits to find cases. Rather, a visitor standing at the gates of any randomly selected factory for a few hours will readily encounter numerous 12- and 13-year old kids who don't seem the least bit concerned about openly acknowledging their ages. Under those circumstances, as Daisey suggests, it would be hard to believe Apple wasn't well aware of, and deliberately winking at, a systemic indifference to the law.

If the point of the monologue were just to provoke an emotional reaction in the audience, as an artistic end in itself, maybe this wouldn't matter. But the monologue is explicitly and forcefully pitched as a call to both consumer activism and political action. In that context, it actually matters what the magnitude of this problem is, relative to others we might focus our time and energy on, and whether Apple is being especially irresponsible, relative to any number of other companies I might give my money to instead.

Those of you who recall the headline are probably wondering what this could possibly have to do with the tragic case of Trayvon Martin. I'll outsource the full rundown to Mother Jones, but the quick version is this:

In itself, that's a matter of news judgment that could probably be defended. But I want to suggest that the disparity here may have something to do with whether one thinks institutional racism remains a serious problem in the United States. Conservatives often seem to think it isn't, and that if anything, the real problem is how often spurious charges of white racism are deployed by their political opponents, while liberals more often tend toward the opposite view. Maybe both groups are drawing justified inferences from the data they're seeing.

Like child labor, institutionalized racism -- in the form of quiet bias as opposed to overt proclamations of white supremacy -- can be hard to detect and quantify rigorously. In both cases, the people closest to the problem have strong incentives to obscure and deny it. So people tend to fall back on what psychologists call the Availability Heuristic, a rule of thumb that says the frequency of an event should correspond to how quickly you can think of examples of it. We automatically pluralize anecdotes into data. Like much of our cognitive toolkit, it often misfires in the age of modern media--it's why people tend to be irrationally concerned with extremely rare threats, like child abduction by strangers, that draw disproportionate media attention.

See the article here:
The Anatomy of Media Bias: Trayvon Martin, Mike Daisey, and the Press

Anatomy of a Media Bias: Trayvon Martin, Mike Daisey, and Us

Julian Sanchez -- Research Fellow, Cato Institute

Like many folks who had seen and been moved by Mike Daisey's powerful monologue "The Agony and the Ecstasy of Steve Jobs," I was profoundly disappointed by the recent revelation that he had not only fabricated some of the work's key scenes, but lied to the journalists and fact checkers at This American Life to prevent them from discovering the deception. There's no point, at this stage, in adding another condemnation to the chorus, but I do want to highlight a pair of sharp pieces by Slate's Daniel Engberger and The Economist's Erica Grieder, responding to the common claim that Daisey's narrative was, as the saying goes, "fake but accurate."

While most commentary on the story has rightly rejected Daisey's invocation of "artistic license" to excuse the use of falsified anecdotes in a work of purported nonfiction, much of it includes the obligatory caveat that Daisey's larger point, the essential picture he paints of labor practices at Chinese suppliers like Foxconn, is true. So, for instance, in his performance, Daisey recounts how in a few hours of interviews outside just a couple of Foxconn plants, he encountered numerous underage workers--girls as young as 12 and 13 years old. Under pressure, he retreated to the claim that he'd spoken (in English) with one girl who identified herself as being 13, and seen several others who "looked young." The translator who accompanied Daisey on these interviews--the one he'd lied to prevent journalists from contacting--denies that there was even the one, and insists that she'd remember if there had been. Now, you don't get a gig as an English translator in China without staying on the good side of the Chinese government, so she might have her own incentive to downplay anything that reflects badly on the labor situation there--but all things considered, I'm inclined to agree with Ira Glass that her account comes across as much more credible than Daisey's.

Suppose we think Daisey probably did just make up this encounter. It's still undeniably the case that there have been underage workers employed by Apple suppliers: The company itself reports identifying 91 in an audit conducted in 2010, the year Daisey visited China. Thus, some argue, even if Daisey lied, the more important thing is that his dramatization reflected the underlying truth in an emotionally resonant way.

I agree with Engberger and Grieder that this line of argument is wrong, and that Daisey's pseudo-anecdote is substantively misleading when you consider what it's really meant to show. Nobody disputes that the number of underaged workers employed by Apple suppliers is greater than zero. But in the context of Foxconn's 300,000-strong workforce, in a country where (as the report suggests) parents are willing to procure fake IDs to help children obtain a coveted factory job, it's also probably not realistic to expect that this would never happen. The real question is whether Apple is making a good faith effort to enforce some screening procedures, identify and correct failures in the process when they occur, and so on.

Daisey's anecdote implicitly makes the far stronger claim that Apple is egregiously, culpably negligent here: Child labor is so prevalent that you scarcely need audits to find cases. Rather, a visitor standing at the gates of any randomly selected factory for a few hours will readily encounter numerous 12- and 13-year old kids who don't seem the least bit concerned about openly acknowledging their ages. Under those circumstances, as Daisey suggests, it would be hard to believe Apple wasn't well aware of, and deliberately winking at, a systemic indifference to the law.

If the point of the monologue were just to provoke an emotional reaction in the audience, as an artistic end in itself, maybe this wouldn't matter. But the monologue is explicitly and forcefully pitched as a call to both consumer activism and political action. In that context, it actually matters what the magnitude of this problem is, relative to others we might focus our time and energy on, and whether Apple is being especially irresponsible, relative to any number of other companies I might give my money to instead.

Those of you who recall the headline are probably wondering what this could possibly have to do with the tragic case of Trayvon Martin. I'll outsource the full rundown to Mother Jones, but the quick version is this:

In itself, that's a matter of news judgment that could probably be defended. But I want to suggest that the disparity here may have something to do with whether one thinks institutional racism remains a serious problem in the United States. Conservatives often seem to think it isn't, and that if anything, the real problem is how often spurious charges of white racism are deployed by their political opponents, while liberals more often tend toward the opposite view. Maybe both groups are drawing justified inferences from the data they're seeing.

Like child labor, institutionalized racism -- in the form of quiet bias as opposed to overt proclamations of white supremacy -- can be hard to detect and quantify rigorously. In both cases, the people closest to the problem have strong incentives to obscure and deny it. So people tend to fall back on what psychologists call the Availability Heuristic, a rule of thumb that says the frequency of an event should correspond to how quickly you can think of examples of it. We automatically pluralize anecdotes into data. Like much of our cognitive toolkit, it often misfires in the age of modern media--it's why people tend to be irrationally concerned with extremely rare threats, like child abduction by strangers, that draw disproportionate media attention.

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Anatomy of a Media Bias: Trayvon Martin, Mike Daisey, and Us

Third Aesthetic Plastic Surgery / Anti Aging Medicine: The Next Generation Symposium Brings Industry Leading Courses …

New York, March 21, 2012 /PRNewswire/ --The third Aesthetic Plastic Surgery / Anti Aging Medicine: The Next Generation Symposium will be held on July 20-22, 2012 at the Conrad New York, a new luxury complex overlooking the Hudson River in lower Manhattan. This interactive, multidisciplinary conference brings together world-class faculty from around the globe who will share ground-breaking research and practical advancements in aesthetic surgery, cosmetic medicine and anti-aging therapy.

The Next Generation Symposium combines the best of continuing medical education, state-of-the-art information that is presented in a manner that encourages forward thinking among the core specialties of Plastic Surgery, Facial Plastic Surgery, Dermatology and Oculoplastic Surgery. Now in its third year, The Next Generation Symposium is distinguished for providing attendees a multitude of practical hands-on instruction, expert insights and pearls from world renowned experts in the field.

As Course Chairman Z. Paul Lorenc, M.D., F.A.C.S states, "We are focused on what is happening now, what is coming next and what the future will bring."

NEW for 2012:

The meeting encourages excellent interaction and discussion among the international core specialty faculty, fostering an atmosphere of different points of view, which creates a positive learning experience. "The Next Generation Symposium will continue to deliver both in the quality of the presentations and the scope of the program," states Executive Co-Chairman,Brian M. Kinney, M.D., F.A.C.S.

About Aesthetic Plastic Surgery & Anti-Aging Medicine: The Next Generation An interdisciplinary approach to disseminating, teaching and promoting the most advanced information and developments in the fields of aesthetic plastic surgery and anti-aging medicine. In view of the rapid pace in development of new technology and techniques employed in these fields, collectively we feel that it is critical that new information is shared in an efficient, unbiased, forward looking manner with the focus of enhancing patient's safety and level of care.

For information about sponsorship opportunities and early bird registration, visit http://www.nextgenmtg.org

Like us on http://www.facebook.com/apssny and follow us on http://www.twitter.com/nextgenmtg for daily updates and additional workshops

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Third Aesthetic Plastic Surgery / Anti Aging Medicine: The Next Generation Symposium Brings Industry Leading Courses ...

VistaGen Therapeutics Enters Strategic Drug Screening Collaboration With Vala Sciences

SOUTH SAN FRANCISCO, CA--(Marketwire -03/21/12)- VistaGen Therapeutics, Inc. (OTC.BB: VSTA.OB - News) (OTCQB: VSTA.OB - News), a biotechnology company applying stem cell technology for drug rescue and cell therapy, and Vala Sciences, Inc., a biotechnology company developing and selling next-generation cell image-based instruments, reagents and analysis software tools, have entered into a strategic collaboration. Their goal is to advance drug safety screening methodologies in the most clinically relevant human in vitro bioassay systems available to researchers today.

Cardiomyocytes are the muscle cells of the heart that provide the force necessary to pump blood throughout the body, and as such are the targets of most of the drug toxicities that directly affect the heart. Many of these drug toxicities result in either arrhythmia (irregular, often fatal, beating of the heart) or reduced ability of the heart to pump the blood necessary to maintain normal health and vigor.

"Our collaboration with Vala directly supports the core drug rescue applications of our Human Clinical Trials in a Test Tube platform," said Shawn K. Singh, JD, VistaGen's Chief Executive Officer. "Our high quality human cardiomyocytes combined with Vala's high throughput electrophysiological assessment capabilities is yet another example of how we are applying our stem cell technology platform within a strategic ecosystem of complementary leading-edge companies and technologies. We seek to drive our drug rescue programs forward and generate a pipeline of new, cardiosafe drug candidates."

Through the collaboration, Vala will use its Kinetic Image Cytometer platform to demonstrate both the suitability and utility of VistaGen's human pluripotent stem cell derived-cardiomyocytes for screening new drug candidates for potential cardiotoxicity over conventional in vitro screening systems and animal models. VistaGen's validated human cardiomyocyte-based bioassay system, CardioSafe 3D, will permit Vala to demonstrate the quality, resolution, applicability and ease of use of its new instrumentation and analysis software to make information-rich, high throughput measurements and generate fundamentally new insights into heart cell drug responses. Accurate, sensitive and reproducible measurement of electrophysiological responses of stem cell-derived cardiomyocytes to new drug candidates is a key element of VistaGen's CardioSafe 3D drug rescue programs. VistaGen's strategic collaboration with Vala is directed towards this goal.

About VistaGen Therapeutics

VistaGen is a biotechnology company applying human pluripotent stem cell technology for drug rescue and cell therapy. VistaGen's drug rescue activities combine its human pluripotent stem cell technology platform, Human Clinical Trials in a Test Tube, with modern medicinal chemistry to generate new chemical variants (Drug Rescue Variants) of once-promising small-molecule drug candidates. These are drug candidates discontinued due to heart toxicity after substantial development by pharmaceutical companies, the U.S. National Institutes of Health (NIH) or university laboratories. VistaGen uses its pluripotent stem cell technology to generate early indications, or predictions, of how humans will ultimately respond to new drug candidates before they are ever tested in humans, bringing human biology to the front end of the drug development process.

Additionally, VistaGen's small molecule drug candidate, AV-101, is in Phase 1b development for treatment of neuropathic pain. Neuropathic pain, a serious and chronic condition causing pain after an injury or disease of the peripheral or central nervous system, affects approximately 1.8 million people in the U.S. alone. VistaGen is also exploring opportunities to leverage its current Phase 1 clinical program to enable additional Phase 2 clinical studies of AV-101 for epilepsy, Parkinson's disease and depression. To date, VistaGen has been awarded over $8.5 million from the NIH for development of AV-101.

About Vala Sciences

Vala Sciences is a San Diego-based biotechnology company that develops and sells cell-image-based instrumentation, reagents and analysis software tools to academic, pharmaceutical and biotechnology scientists. Vala's IC 200 class of instrumentation, and CyteSeer Automated Image Cytometry software convert labor-intensive qualitative observations of biological changes that can take from days to months, into accurate measurements delivered automatically in minutes.

Cautionary Statement Regarding Forward Looking Statements

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VistaGen Therapeutics Enters Strategic Drug Screening Collaboration With Vala Sciences

Nemours researchers uncover new evidence of cancer-causing agent present in gaseous phase of cigarette smoke

Public release date: 21-Mar-2012 [ | E-mail | Share ]

Contact: Karen Bengston kbengsto@nemours.org 302-298-7319 Nemours

Wilmington, DE A team of researchers led by A. K. Rajasekaran, PhD, Director of the Nemours Center for Childhood Cancer Research, has shown that a key protein involved in cell function and regulation is stopped by a substance present in cigarette smoke. Their work is published online in the American Journal of Physiology - Lung Cell and Molecular Physiology.

Cigarette smoke is well recognized as a cause of lung cancer and is associated with many other forms of cancer in adults. Cigarette smoke has more than 4,000 components, many of which are linked to the development and progression of lung cancer. Evidence has shown secondhand smoke to be as dangerous as primary smoke due to its impact on the cells of the body.

In the study, the authors found a cancer-causing agent called reactive oxygen species (ROS) present in the gaseous phase of cigarette smoke that has the ability to inhibit normal cell function. Exposure to the secondhand smoke produced by as little as two cigarettes was found to almost completely stop the function of a cell's sodium pump within a few hours. In normal cells, the sodium pump plays a critical role transporting potassium into the cell and sodium out of the cell. The competence of the cell's sodium pump, i.e., its inability to regulate sodium, is predictive of cell damage, disease progression and ultimately, survival.

"This is critical information with regard to secondhand smoke," said Dr. Rajasekaran. "We now know that one need not inhale the particulate matter present in secondhand smoke to suffer the consequence of smoking. Exposure to the gaseous substance alone, which you breathe while standing near a smoker, is sufficient to cause harm." Dr. Lee Goodglick, Associate Professor in the Department of Pathology and Laboratory Medicine, UCLA, and co-senior author of the study, noted, "Few reliable lung cancer biomarkers that could predict survival, treatment options or response to therapy exist today. Even fewer have been recognized where the function of the biomarker is known, yielding important information about the mechanism of action. This study really accomplishes both."

This research is the latest finding in the compendium of evidence that supports protecting children from exposure to cigarette smoke. Excessive exposure to cigarette smoke during childhood can facilitate lung cancer development as children grow into adults. While more research is needed to understand the consequences of sodium pump inhibition by cigarette smoke, this study reveals that secondhand smoke is even more dangerous than previously thought.

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About the Nemours Center for Childhood Cancer Research

The Nemours Center for Childhood Cancer Research, part of Nemours Biomedical Research at the Alfred I. duPont Hospital for Children, is located in a fully renovated laboratory space on Rockland Road in Wilmington, DE. The goal of the center is to evolve into a leader in research focusing on the discovery of new drugs and biomarkers for childhood cancers and reduced side effects arising due to cancer treatment in children. The NCCCR works closely with the University of Delaware, Christiana Care - Helen F. Graham Cancer Center, the Delaware Biotechnology Institute and Thomas Jefferson University. For more information, visit http://www.nemours.org/link/ncccr.

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Nemours researchers uncover new evidence of cancer-causing agent present in gaseous phase of cigarette smoke

Wolters Kluwer Health Releases First Medical Journal iPad(r) App in Pathology

Newswise LONDON (March 21, 2012) Wolters Kluwer Health announced today the release of an iPad app for the medical journal, Pathology. The app provides health care professionals with full mobile accessibility to the latest research into all aspects of pathology. Pathology is published by Lippincott Williams & Wilkins (LWW), part of Wolters Kluwer Health on behalf of the Royal College of Pathologists of Australasia (RCPA).

Pathology for the iPad uses optimized digital technology to provide a fully portable and enhanced print-like reading experience. It is the first iPad app available that offers access to the very latest original scientific research and reviews into pathology.

The RCPA is delighted that the cutting edge research and review topics published in Pathology will now be available via an iPad app said Professor Brett Delahunt, Editor of Pathology. Such convenient and user-friendly access will allow pathologists to fit journal reading more easily into their busy schedules. This, in turn will help them in applying advancements in medicine into their important daily work, ensuring patients receive the best of care.

Were delighted to partner with the Royal College of Pathologists of Australasia to bring the Pathology journal iPad app to members offering a dynamic, integrated experience with their journal, added Karen Abramson, President and CEO of Wolters Kluwer Health Medical Research.

Along with full-text downloads of each issue, the new app allows the user to: Share articles via email or social media Adjust text sizing with "pinch and zoom" View multimedia videos, images, and supplements Store or delete downloaded issues Browse issues via Quick View Scroll quickly through abstract summaries Receive notifications about new issues Link to the journal website (www.rcpa-pathologyjournal.com) for additional reading and searching archives, etc.

The Pathology iPad app is available free of charge from the App StoreSM. The April 2012 issue is also free for users to experience the app. Once access controls are applied, future issues will only be available to subscribers and RCPA fellows.

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About Pathology Pathology Official Journal of the Royal College of Pathologists of Australasia (RCPA) is committed to publishing peer-reviewed, original articles related to the science of pathology in its broadest sense, including anatomical pathology, chemical pathology and biochemistry, cytopathology, experimental pathology, forensic pathology and morbid anatomy, genetics, haematology, immunology and immunopathology, microbiology and molecular pathology.

About the Royal College of Pathologists of Australasia The Royal College of Pathologists of Australasia (RCPA) has been responsible for the training and professional development of pathologists for more than fifty years. It is also responsible for the promotion of the science and practice of Pathology. The principal object of the College is: to promote the study of the science and practice of Pathology in relation to medicine; to encourage research in pathology and ancillary sciences, to bring together pathologists for their common benefit and for scientific discussions and demonstrations; and to disseminate knowledge of the principles and practice of pathology in relation to medicine by such means as may be thought fit.

About Lippincott Williams & Wilkins Lippincott Williams & Wilkins (LWW) is a leading international publisher of trusted content delivered in innovative ways to practitioners, professionals and students to learn new skills, stay current on their practice, and make important decisions to improve patient care and clinical outcomes.

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Wolters Kluwer Health Releases First Medical Journal iPad(r) App in Pathology

State pension to be simplified

The Chancellor has pledged to combine the two state pensions into one simplified pension, as well as increasing the state pension age automatically in line with rises in longevity.

In Wedneday's Budget, as part of wider plans to simplify the UK's complicated tax system, George Osborne announced that the second state pension will be scrapped and a new single-tier pension will be launched for future pensioners.

It is estimated that it will be about 140 a week. The full basic state pension is currently 102.15 a week, rising to 107.45 next month.

In his speech, Osborne joked about the complexity of the second state pension: "Such is the complexity of this means-tested system, only someone like our pensions minister can work out exactly what someone's entitled to - and what they need to save.

"So I can confirm that we will introduce a new single-tier pension for future pensioners, set above the means test."

The new pension will be based on contributions and will cost no more than the current system. The government will publish further details in the next few months.

"A single, generous, basic state pension for those who have worked and saved hard all their lives," the Chancellor declared.

He also announced that to tackle the long-term challenges of an ageing population, there will be an automatic review of further increases to the state pension age to ensure it keeps pace with increases in longevity. Further details on this will be published this summer.

Baroness Greengross, chief executive of the International Longevity Centre-UK (ILC-UK), welcomed the automatic link: "The government is right to consider how the state pension age needs to increase in line with longevity. It is simply not sustainable for the state to adequately support us for the increasing number of years we are spending in retirement."

She added: "Whilst many of us can expect to live 15 or 20 years after state pension age, parts of the country see much lower life expectancy. Further increases in state pension age must go alongside initiatives to tackle inequalities in health and healthy life expectancy."

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State pension to be simplified

DNA test determines kidnapped baby's father

HOUSTON -

A DNA test has proved with 99 percent certainty that the man claiming to be the father of a child kidnapped eight years ago is the biological father.

The test results were revealed in court on Wednesday.

Miguel Morin, 8, was kidnapped in November 2004. He was 8 months old when he disappeared.

Miguel was found earlier this month after a woman turned in her sister, Krystle Rochelle Tanner. Tanner has been charged with felony kidnapping.

Fernando Morin has been proven to be Miguel's father, it has not been determined who Miguel's mother is. Auboni Champion-Morin has submitted her DNA for testing and results were expected to be returned on Thursday.

Champion-Morin said she left her son with Tanner, a friend whom she considered the child's godmother. When she went to pick up Miguel the next day, both Tanner and the child were gone.

According to Children's Protective Services workers, Miguel was given a new name and a new birth date and, when shown a picture of Tanner, he identified her as his mother. Officials said he thinks he is 6 years old.

A psychologist said Miguel is frightened, shy and behind emotionally and psychologically. He does not attend school, officials said.

"The child doesn't really know what's going on," Morin said. "He's been lied to his whole life."

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DNA test determines kidnapped baby's father

Posted in DNA

TMJ: Stem cell biology and engineering toward clinical translation

Public release date: 21-Mar-2012 [ | E-mail | Share ]

Contact: Ingrid L. Thomas ithomas@aadronline.org 703-299-8084 International & American Associations for Dental Research

Tampa, Fla., USA On March 23, during the 41st Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 36th Annual Meeting of the Canadian Association for Dental Research, a symposium titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" will provide a rare forum for multidisciplinary discussion of the biology, engineering and clinical translation of fundamental discoveries towards novel clinical therapy. The symposium is co-sponsored by the Craniofacial Biology, Mineralized Tissue and Neuroscience Scientific Research Groups of the International Association for Dental Research. The presentations in this multidisciplinary symposium will represent broad and yet comprehensive approaches toward the understanding of the origin, homeostasis, differentiation, hormonal regulation and bioengineering of temporomandibular joint (TMJ) tissues.

TMJ disorders are a poorly understood cluster of diseases, ranging from neuromuscular pain to severe forms of arthritis. Recently, stem/progenitor cells have been identified in TMJ disc and condyle, with potential origin from neural crest cells in development. Putative TMJ stem/progenitor cells are subjected to local, hormonal and other systemic factors in homeostasis in multiple processes that warrant better elucidation. In parallel, there is an acute demand in the clinical community for the regeneration of various TMJ components, including the disc, condyle, synovium and the mandible.

This symposium will not only provide new aspects of a timely and under-studied subject of TMJ biology and therapeutics, but also use TMJ as a model for the study of other dental and craniofacial structures and diseases.

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This is a summary of sequence #87 titled "TMJ: Stem Cell Biology and Engineering toward Clinical Translation" which will feature abstracts to be presented by M. Embree, M. Detamore, A. Le and S. Kapila at the Annual Meeting of the American Association for Dental Research. This symposium will take place at 8 a.m. on Friday, March 23, 2012, in room 10 of the Tampa Convention Center.

About the American Association for Dental Research

The American Association for Dental Research (AADR), headquartered in Alexandria, Va., is a nonprofit organization with nearly 4,000 members in the United States. Its mission is: (1) to advance research and increase knowledge for the improvement of oral health; (2) to support and represent the oral health research community; and (3) to facilitate the communication and application of research findings. AADR is the largest Division of the International Association for Dental Research (IADR).

To learn more about the AADR, visit http://www.aadronline.org.

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TMJ: Stem cell biology and engineering toward clinical translation