Blutgerinnung: Forschung mittels Computersimulation und medizinisch angewandter Nanotechnologie

Wissenschaftler des Heidelberger Instituts fuer Theoretische Studien (HITS) und Aerzte der Universitaetsmedizin Mannheim sind an einer neuen Forschergruppe der Deutschen Forschungsgemeinschaft zur Blutgerinnung beteiligt. Langfristiges Ziel der Zusammenarbeit von Wissenschaftlern ist es, die Diagnostik und Therapie von Blutgerinnungsstoerungen, Thrombosen und Schlaganfaellen zu verbessern.

New cloaking material hides objects otherwise visible to the human eye

Exotic artificial composite materials called metamaterials can be engineered with certain electromagnetic properties that allows them to act as invisibility cloaks. These materials bend all light or other electromagnetic waves around an object hidden inside a metamaterial cloak, to emerge on the other side as if they had passed through an empty volume of space. Researchers have already been experimenting with cloaking devices for various, usually longer wavelengths such as microwave or infrared waves. Recently, even graphene has been added to the family of cloaking materials. Now, for the first time, a team of scientists at UC Berkeley have devised an invisibility cloak material that hides objects from detection using light that is visible to humans.

NSF award to develop neural implants using graphene

Mark Ming-Cheng Cheng, Ph.D., assistant professor of electrical and computer engineering at Wayne State University, recently received a five-year, $475,000 Faculty Early Career Development (CAREER) grant from the National Science Foundation to study the potential of graphene, a novel carbon material, in the development of a reliable, high-performance, long-term implantable electrode system to improve quality of life using nanotechnology.

Autopsy rates declining

There are a number of reasons for this, namely, ubiqutous pre-mortem imaging with improved techniques and detection of disease pre-mortem, lack of payment/reimbursement, more out of hosptial deaths and decreased number of physicians trying to obtain consent.  I have seen the autopsy rate at some hospitals in my career as low as 8%.  What is not clear to me is why/how JCAHO does not cite for these kinds of findings and why more is not done in clinical medicine to obtain consent for what is still widely considered the "gold standard" in medicine for clinicopathologic correlation and assessing effects of therapy and natural history of disease.

It is said the Virchow himself performed over 50,000 autopsies.  I can't imagine doing that many, but these numbers are paltry.

The Wall Street Journal (8/4, Hobson) "Health Blog" reported that CDC statistics show that in 2007, autopsies were performed on 8.5% of deaths, compared with 19.3% of deaths in 1972. CDC scientist Donna Hoyert says this may be due to medical professionals believing that autopsies are unnecessary due to modern technology. However, doctors point out that autopsies can contradict imaging findings, and alert families to genetic conditions. The report also notes that the Joint Commission has removed a rule that hospitals must perform autopsies on 20% to 25% of deaths. 

HealthDay (8/4, Preidt) reported that "in 1972, deaths due to disease accounted for 79 percent of autopsies, while deaths due to external causes such as injury or murder accounted for 19 percent. By 2007, the respective percentages were 46 percent and 50 percent, the investigators found. External causes of death -- including murder, accidental injury, suicide or undetermined cause -- accounted for nine of the 10 most frequently autopsied causes of death in 2007." The report also showed that "while the number of deaths among older people increased from 1972 to 2007, autopsied deaths were increasingly concentrated in the one to 34 and 35 to 64 age groups." WebMD (8/4, Hendrick) also covered the study.

 

http://blogs.wsj.com/health/2011/08/04/the-incredible-shrinking-autopsy/?mod=WSJBlog&mod=WSJ_health

 

PathXL BioBank Launched at SMi’s Biobanking Conference

Last month i-Path attended SMi’s Biobanking Conference in London and launched a new product, PathXL BioBank.  During the two-day conference a number of thought leaders from around the world made presentations highlighting the exciting work of the biobanking industry.

A biobank is a facility to store and archive biological samples primarily for use in research. With each biobank taking their own approach to set up and operations, it is a dynamic and fast paced environment.  Path XL BioBank allows users to store, track and check in / out tissue samples using a sophisticated web-based interface. Customers have the flexibility to use their own biobanking software whilst incorporating the PathXL image viewer or to use PathXL BioBank as their database and management software with virtual images integrated.

“Moving into the biobanking sector is an exciting step for i-Path, and we were delighted to see PathXL BioBank so well received at the Biobanking Conference.”
Phil Murray, i-Path Executive VP & Sales Director

Key benefits
•    Immediate access to virtual slides, eliminating the inefficiency of physically retrieving slide
•    Slide scanning conducted by i-Path experts who will guide you through the scanning options and QC all scans
•    All virtual slides are hosted on a secure, high performance image server environment providing a fast reliable service
•    Securely log in anytime from anywhere in the world to manage your tissue research project
•    Share digital slides with collaborators anywhere in the world

“We integrated PathXL with our NI Biobank database to enable researchers to view our catalogue of samples online, from anywhere in the world. When a sample is added to the NI Biobank it immediately appears in our online catalogue. Researchers will then be able to select and order samples from the NI Biobank in full confidence that all the samples they receive will be useable in their research.”
Dr. Jacqueline James, Northern Ireland Biobank Scientific Lead

Earn CME at Pathology Visions – NEW this year

New this year -- CME will be offered to physicians attending the meeting.  I know from personal involvement this was a team effort with a couple of pathologists involved with the Digital Pathology Association (DPA) and the DPA staff.  

My sense from years past is that more pathologists would attend if CME were offered.  Now it is.

Earn up to 13 hours at this meeting.  The talks, combined with the exhibits and networking opportunities should place Pathology Visions high on your list of the many Fall meetings to attend.

I use to say that the Visions conference was a greet meeting in a great venue but now add on the CME and will only add to the meeting program and offerings.

My personal thanks to DPA staff -- in particular Lindsey M. and Michael W. for making this a reality.

Please see attached announcement.

Download Dpa_blogCME_01_ACT.

Webinar from Aperio — August 23 — Select Topics in Image Analysis Series

Select Topics in Image Analysis:
Algorithm Tuning for IHC Analysis and An Introduction to Genie

August 23, 2011

8:00 am Pacific Time, 11:00 am Eastern Time
(4:00 pm London GMT / 10:00 am Mexico City Standard Time)
and
 
4:00 pm Pacific Time, 7:00 pm Eastern Time
(8:00 am Japan Time / 9:00 am Australia EST August 24)

  

Presenter:
Marc Friedman, Ph.D, 
Imaging Scientist and Digital Pathology Consultant, Aperio

In this 60-minute complimentary webinar, Dr. Friedman will present an overview of algorithm tuning for IHC probes, as well as an introduction to Genie and how it is used as a pre-processor for other image analysis algorithms.  

To register for the 8 am PDT session, click here.

https://aperio.webex.com/aperio/onstage/g.php?d=768917066&t=a

To register for the 4 pm PDT session, click here.

https://aperio.webex.com/aperio/onstage/g.php?d=765740143&t=a

You may also register by visiting the Aperio Events page.

You will receive a confirmation email upon registration with a web link that will lead you to the online event. Simply visit the link at the assigned time. The session is secure and easy to access. If you have any questions or would like additional information, please contact the Aperio Events Team at events@aperio.comor 760.539.1192.